CINXE.COM

<!DOCTYPE html> <html lang="en"> <head>  <meta http-equiv="X-UA-Compatible" content="IE=edge" /> <meta name="format-detection" content="telephone=no" /> <meta name="viewport" content="width=device-width, initial-scale=1.0, maximum-scale=1.0, user-scalable=0" /> <script> function callIfOrWhenWindowLoaded(func) { if (func != undefined) { if (document.readyState == 'complete' && typeof ($m) !== 'undefined') { func(); } else { if (window.attachEvent) { window.attachEvent('onload', func); } else if (window.addEventListener) { window.addEventListener('load', func, false); } else { document.addEventListener('load', func, false); } } } } </script> <script type="text/javascript"> if (!window.console) console = {log: function() {}, info: function() {}}; </script>  <title> CD11b Monoclonal Antibody (M1/70), PE-Cyanine5 (15-0112-82) </title> <link rel="preload stylesheet" type="text/css" as="style" href="/order/genome-database/assets/js/angular/dist/gsh/gsh-header-v2.css?version=Local&time=20240917&build-time=2024-11-22T02:34:20+0000"/> <link rel="preload stylesheet" type="text/css" as="style" href="/order/genome-database/assets/css/font-common.css?version=Local&time=20240917&build-time=2024-11-22T02:34:20+0000"/> <link rel="canonical" href="https://www.thermofisher.com/antibody/product/CD11b-Antibody-clone-M1-70-Monoclonal/15-0112-82"/> <link rel="alternate" href="https://www.thermofisher.com/antibody/product/CD11b-Antibody-clone-M1-70-Monoclonal/15-0112-82" hreflang="en-us"/> <link rel="alternate" href="https://www.thermofisher.cn/cn/zh/antibody/product/CD11b-Antibody-clone-M1-70-Monoclonal/15-0112-82" hreflang="zh-cn"/> <link rel="alternate" href="https://www.thermofisher.cn/cn/en/antibody/product/CD11b-Antibody-clone-M1-70-Monoclonal/15-0112-82" hreflang="en-cn"/> <link rel="alternate" href="https://www.thermofisher.com/antibody/product/CD11b-Antibody-clone-M1-70-Monoclonal/15-0112-82" hreflang="x-default"/>          <meta name="description" content="Invitrogen Anti-CD11b Monoclonal (M1/70), eBioscience™, Catalog # 15-0112-82. Tested in Flow Cytometry (Flow) applications. This antibody reacts with Mouse samples. Supplied as 100 µg purified antibody (0.2 mg/mL)." /> <link rel="dns-prefetch" href="//tools.thermofisher.com" /> <link rel="dns-prefetch" href="//downloads.thermofisher.com" /> <link rel="dns-prefetch" href="//assets.thermofisher.com" /> <link rel="preconnect" href="//assets.adobedtm.com" /> <link rel="dns-prefetch" href="//assets.adobedtm.com" />  <meta charset="utf-8" /> <meta http-equiv="X-UA-Compatible" content="IE=edge" /> <meta name="author" content="" /> <meta http-equiv="cache-control" content="no-cache, must-revalidate" /> <meta http-equiv="expires" content="0" /> <meta http-equiv="pragma" content="no-cache" />  <link rel="preload" as="script" href="/etc/designs/lifetech/clientlibs/base-jquery.min.js?version=Local&time=20240917&build-time=2024-11-22T02:34:20+0000"/> <link rel="preload" as="script" href="/etc/designs/lifetech/clientlibs/base-bootstrap.min.js?version=Local&time=20240917&build-time=2024-11-22T02:34:20+0000"/> <link rel="preload" as="script" href="/shared-static/scripts/global-variables.js"> <link rel="preload" as="script" href="/shared-static/scripts/global-functions.js">    </head> <body> <script> if (typeof $m === 'undefined' || !$m) { var $m = {}; } $m.basepath = "//" + window.location.host + "/order/genome-database/"; $m.pageName = 'PDP'; $m.curSym = ''; $m.currencyDisplay = ''; $m.lt_rev='VLocal', // Used to defeat caching $m.domainName = 'LT'; $m.portalBaseURL = 'https://www.thermofisher.com/'; $m.keywordTypeaheadBaseURL = 'https://magellan.tfcom-eks-na-magellanprod.magellanprod.thermofisher.net/solr/lt-magellan-search-core/select'; $m.inventoryLocationCountryLists = 'UK-AT-BE-BG-HR-CZ-DK-EE-FI-FR-DE-GB-GR-HU-IS-IE-IL-IT-LT-LU-MT-NL-NO-PL-PT-RO-SK-ES-SE-CH-TR'; $m.isLeadTimeEnabled = false; $m.mapDataServer = 'https://www.thermofisher.com/api/magellan/alignmap/map-server'; $m.CID = ''; $m.ICID = ''; $m.isLoggedIn = false; $m.pluginURLParm = ''; $m.isoLanguage = 'en'; $m.translationEnabledProducts = 'antibody;immunoassay'; $m.buildNumber = 'Local'; $m.buildTimestamp = '2024-11-22T02:34:20+0000'; //TO-DO Update this whenever there is change in strategy for Apple $m.apple = '-apple'; $m.useFisherSciMfgPart = 'false'; $m.useAdobeLaunch = 'true'; </script> <header class="header"> <div class="globalHeader" id="hfGlobalHeader" data-orig="tfpt-header-footer" data-app-env="prod" data-site="tf" data-hostname="www.thermofisher.com" data-x-host="www.thermofisher.com" data-env="prod" data-hash="468bd07150dbbf" data-version="4.03.29" data-analytics-section="header" data-aem-syndication-info="(sg:en-sg:anonymous:https-tf)" data-aem-syndication-timestamp="globalHeader: Wed, 27 Nov 2024 23:24:21 GMT" data-optional-selectors="inlineCss,globalRoute">          <script type="text/javascript"> // define the console object if it is not available as a temporary fix for console.log issues on IE 8 if(!(window.console && console.log)) { console = { log: function(){}, debug: function(){}, info: function(){}, warn: function(){}, error: function(){} }; } </script>  <script type="text/javascript"> window.performance && window.performance.mark && window.performance.mark("globalHeader:renderBegin"); </script>  <script data-inline-file-name='trust-arc.min.js' data-inline-site='tf'>/* Hash: 468bd07150dbbf Source: /tf/js/dist/trust-arc.min.js */ window.hfSite="tf",window.trustArc={consentInsights:{api_key:"",secret:""},init:function(e,t,n,r){if(window.trustArc.countryCode=e,window.trustArc.languageCode=t,window.trustArc.ut=window.trustArc.preferences()?"RETURNING":"NEW",window.trustArc.privacyURL=document.location.origin+"/"+e+"/"+t+"/home/global/privacy-policy.html",window.trustArc.cookieURL=document.location.origin+"/"+e+"/"+t+"/home/global/how-cookies-are-used.html","uk"===e&&(e="gb"),"ic"===e&&(e="es"),"br"===e&&"pt"===t&&(t="pt_br"),"zh"===t&&(t="zh_hans"),"zt"===t&&(t="zh_cn"),window.trustArc.CMurl="//consent.truste.com/notice?c=teconsent&pcookie=true&js=nj&gtm=true&noticeType=bb&text=true&domain="+n+"&country="+e+"&language="+t+"&privacypolicylink=",window.trustArc.tagManagerURL=r,window.trustArc.injectCM(),r.indexOf("development")>-1||r.indexOf("staging")>-1?(window.trustArc.consentInsights.api_key="CI-7153680989",window.trustArc.consentInsights.secret="791102116598381495740862696243996077676903892648153044076559127326113493625826883438963034185582914868990705664"):(window.trustArc.consentInsights.api_key="CI-3929813243",window.trustArc.consentInsights.secret="810274278902470721624405905887912991104270295366493143855663183685375235160482241511078341257235422202822656000"),!window.sessionStorage.ciVisitId&&!window.localStorage.consentInsightsVisitRecorded){var s=URL.createObjectURL(new Blob);window.sessionStorage.ciVisitId=s.substring(s.lastIndexOf("/")+1),window.trustArc.sendMetric("visit")}document.body.addEventListener("truste-consent",function(){var e=getCookie("notice_gdpr_prefs");if(window.localStorage.consentInsightsConsentRecorded||window.trustArc.sendMetric("consent"),window.trustArc.tagManagerURL&&!document.querySelector("#tagmanager")&&(e.includes("1")||e.includes("2"))){var t=document.createElement("script");t.id="tagmanager",t.src=window.trustArc.tagManagerURL,t.type="text/javascript",document.head.appendChild(t)}}),setTimeout(function(){var e=document.querySelector("#truste-consent-track");e&&"block"===e.style.display&&window.trustArc.sendMetric("impression")},1e3),window.addEventListener("message",function(e){try{"cm_loading"!==JSON.parse(e.data).message||window.localStorage.consentInsightsImpressionRecorded||window.trustArc.sendMetric("impression")}catch(e){"SyntaxError"!=e.name&&console.log(e)}},!1)},injectCM:function(){var e=document.createElement("script");e.async=!0,e.src=window.trustArc.CMurl+window.trustArc.privacyURL+"&cookieLink="+window.trustArc.cookieURL,e.setAttribute("crossorigin",!0),document.head.appendChild(e)},preferences:function(){return getCookie("notice_gdpr_prefs")},requiredReady:function(){return!0},functionalReady:function(){return window.trustArc.preferences().includes("1")},advertisementReady:function(){return window.trustArc.preferences().includes("2")},enable:function(e){return e||!e&&window.location.href.includes("eta=true")},sendMetric:function(e){var t=new URL("https://consent-insights-3c23a978f31a.herokuapp.com/api/v1/visits/capture"),n=new URL("https://consent-insights-3c23a978f31a.herokuapp.com/api/v1/impressions/capture"),r=new URL("https://consent-insights-3c23a978f31a.herokuapp.com/api/v1/consents/capture"),s="";switch(e){case"visit":s=t;break;case"impression":s=n;break;case"consent":s=r}s.searchParams.append("api_key",window.trustArc.consentInsights.api_key),s.searchParams.append("secret",window.trustArc.consentInsights.secret),s.searchParams.append("country",window.trustArc.countryCode),s.searchParams.append("language",window.trustArc.languageCode),s.searchParams.append("visit_id",window.sessionStorage.ciVisitId),s.searchParams.append("ut",window.trustArc.ut),window.trustArc.preferences()&&s.searchParams.append("preferences",window.trustArc.preferences()),s.searchParams.append("ua",navigator.userAgent),s.searchParams.append("title",document.title),s.searchParams.append("url",window.location.href);var i=document.createElement("img");i.src=s,i.alt="1x1 image pixel for data collection",document.body.appendChild(i),"visit"===e&&(window.localStorage.consentInsightsVisitRecorded=!0),"impression"===e&&(window.localStorage.consentInsightsImpressionRecorded=!0),"consent"===e&&(window.localStorage.consentInsightsConsentRecorded=!0)}};</script> <script type="text/javascript"> document.addEventListener("DOMContentLoaded", function(){ if (window.trustArc.enable(true) && !(/how-cookies-are-used|privacy-policy/i.test(window.location.href))) { window.trustArc.init("sg", "en", "thermofisher.com", "https://assets.adobedtm.com/launch-ENeecb77f1160a4928a492ff040f7110c7.min.js"); } }) </script> <script id="inlineHFJavascriptConfig" type="text/javascript"> if ( !window.globalHeaderConfig ) { var globalHeaderConfig = {}; } globalHeaderConfig.logoImagePath = '/content/dam/LifeTech/Images/Header/logo-color.png' globalHeaderConfig.scmsEuLogoLinkHref = 'https://commerce.thermofisher.com/customersite/schome.cfm'; globalHeaderConfig.scmsEuLogoImageIe6Path = '/content/dam/LifeTech/Images/Header/supply-centre.png'; globalHeaderConfig.scmsEuLogoImagePath = '/content/dam/LifeTech/Images/Header/supply-center.png'; globalHeaderConfig.scmsEuLogoImagePrintPath = '/content/dam/LifeTech/Images/Header/supply-centre.png'; globalHeaderConfig.scmsShipToLabLogoLinkHref = 'https://commerce.thermofisher.com/customersite/schome.cfm'; globalHeaderConfig.scmsShipToLabLogoImageIe6Path = '/content/dam/LifeTech/Images/Header/logo-color.png'; globalHeaderConfig.scmsShipToLabLogoImagePath = '/content/dam/LifeTech/Images/Header/logo-color.png'; globalHeaderConfig.scmsShipToLabLogoImagePrintPath = '/content/dam/LifeTech/Images/Header/logo-black.png'; globalHeaderConfig.scmsEuShipToLabLogoLinkHref = 'https://commerce.thermofisher.com/customersite/schome.cfm'; globalHeaderConfig.scmsEuShipToLabLogoImageIe6Path = '/content/dam/LifeTech/Images/Header/logo-color.png'; globalHeaderConfig.scmsEuShipToLabLogoImagePath = '/content/dam/LifeTech/Images/Header/logo-color.png'; globalHeaderConfig.scmsEuShipToLabLogoImagePrintPath = '/content/dam/LifeTech/Images/Header/logo-black.png'; globalHeaderConfig.scmsNavLinkTextForEU = 'Supply Centre Settings'; globalHeaderConfig.scmsNavUnlockLinkTextForEU = ''; globalHeaderConfig.scmsNavChangeLocationLinkTextForEU = 'Change My Location'; globalHeaderConfig.scmsNavSetStartPageLinkTextForEU = 'Set My Start Page'; globalHeaderConfig.scmsNavSupplyCenterHomeLinkTextForEU = 'Supply Centre Home'; globalHeaderConfig.scmsNavSupplyCenterHomeForLabLinkTextForEU = 'Supply Centre Home'; globalHeaderConfig.utilityBarSignInForwardLinkHref = '/auth/initiate'; </script> <script data-inline-file-name="https://www.thermofisher.com/dm-offers/preload.min.js"> if(!window.preloadOffers){window.preloadOffers={version:"2024.4.0"};function preLoadOffer(e,t,r,o,f){var n=document.querySelector("#"+e+" , ."+e),d,l;if(!n){if(r<25){r++;setTimeout((function(){preLoadOffer(e,t,r,o,f)}),t);return}return}if(o&&preloadVerifyHtmlOffer(o)){try{n.innerHTML=o;l=n.querySelectorAll("script");for(d=0;d<l.length;d++){preloadOffers.scriptNode.push(l[d])}n.setAttribute("preloaded","true");n.setAttribute("offerUrl",f);dispatchPreloadOffersEvent("requestPostEvents")}catch(e){console.error("could not execute script : "+e)}if(!!f&&f.length>1){try{n.querySelector("a").href=f;console.log("in preload added offerUrl",f,"to",e)}catch(t){console.warn("in preload failed to add offerUrl",f,"to",e)}}}else{showDefaultOfferContent(n);n.setAttribute("preloaded-default","true")}}function preloadVerifyHtmlOffer(e){var t=false,r,o;if(typeof e!=="undefined"&&e.length>0){if(e.indexOf("<head")===-1){t=true}else{r=(new DOMParser).parseFromString(e,"text/html");o=r.querySelector("head");if(o.childElementCount===0){t=true}}}return t}function showDefaultOfferContent(e){try{e.setAttribute("preloaded","false");var t=e.querySelector(" .loading-wheel-block"),r=e.querySelector(" .loading-wheel-block .loading-wheel"),o=e.querySelector(" .loading-wheel-block .defaultOffer");t.style.padding="0px";r.remove();o.removeAttribute("style")}catch(t){console.log("Preload offers - no default offer for div :: "+e.getAttribute("id"))}}function processOfferResp(e){if(e){var t=JSON.parse(e),r,o,f;window.preloadOffers.response=t;window.preloadOffers.scriptNode=[];if(t&&t.hasOwnProperty("offerPlacementMap")){r=t["offerPlacementMap"];for(o in r){f=r[o];preLoadOffer(o,100,1,f.offerHTML,f.offerUrl)}}}}function dispatchPreloadOffersEvent(e){if(document.createEvent){var t=document.createEvent("Event");t.initEvent(e,true,true);document.dispatchEvent(t)}else if(document.createEventObject){if(!!document.documentElement[e]){document.documentElement[e]=1}document.documentElement[e]++}}function getCookie(e){var t=e+"=",r=document.cookie,o=r.indexOf(t),f=null,n;if(o!==-1){n=r.indexOf("; ",o);if(n===-1){n=r.length}f=r.slice(o+t.length,n);f=unescape(f)}return f}if(getCookie("cq-authoring-mode")===null){var preloadUrl="/event/offer/preload",xhttp=new XMLHttpRequest;xhttp.onreadystatechange=function(){if(this.readyState===4){if(!window.preloadOffers){window.preloadOffers={}}if(this.status===200){window.preloadOffers.succeed=true;processOfferResp(this.responseText)}else{window.preloadOffers.succeed=false}dispatchPreloadOffersEvent("preloadOffers");window.preloadOffers.status=this.status;window.preloadOffers.statusText=this.statusText}};xhttp.ontimeout=function(){window.preloadOffers.succeed=false;dispatchPreloadOffersEvent("preloadOffers")};xhttp.open("POST",preloadUrl,true);xhttp.setRequestHeader("Content-Type","application/json;charset=UTF-8");xhttp.timeout=4e3;xhttp.send()}} </script>  <script type="text/javascript"> window.performance && window.performance.mark && window.performance.mark("header_0"); </script>  <style data-inline-file-name='header.min.css' data-inline-site='tf'>/* Hash: 468bd07150dbbf Source: /tf/css/dist/header.min.css */ @charset "UTF-8";@font-face{font-family:HelveticaNeue;src:url(/designsystem-cdn/fonts/HelveticaNeueLTW01-35Thin.eot?#iefix);src:url(/designsystem-cdn/fonts/HelveticaNeueLTW01-35Thin.eot?#iefix) format("eot"),url(/designsystem-cdn/fonts/HelveticaNeueLTW01-35Thin.woff2) format("woff2");font-weight:lighter;font-style:normal;font-display:swap}@font-face{font-family:HelveticaNeue;src:url(/designsystem-cdn/fonts/HelveticaNeueLTW01-35Thin.eot?#iefix);src:url(/designsystem-cdn/fonts/HelveticaNeueLTW01-35Thin.eot?#iefix) format("eot"),url(/designsystem-cdn/fonts/HelveticaNeueLTW01-35Thin.woff2) format("woff2");font-weight:100;font-style:normal;font-display:swap}@font-face{font-family:HelveticaNeue;src:url(/designsystem-cdn/fonts/HelveticaNeueLTW01-45Light.eot?#iefix);src:url(/designsystem-cdn/fonts/HelveticaNeueLTW01-45Light.eot?#iefix) format("eot"),url(/designsystem-cdn/fonts/HelveticaNeueLTW01-45Light.woff2) format("woff2");font-weight:200;font-style:normal;font-display:swap}@font-face{font-family:HelveticaNeue;src:url(/designsystem-cdn/fonts/HelveticaNeueLTW01-45Light.eot?#iefix);src:url(/designsystem-cdn/fonts/HelveticaNeueLTW01-45Light.eot?#iefix) format("eot"),url(/designsystem-cdn/fonts/HelveticaNeueLTW01-45Light.woff2) format("woff2");font-weight:300;font-style:normal;font-display:swap}@font-face{font-family:HelveticaNeue;src:url(/designsystem-cdn/fonts/HelveticaNeueLTW01-55Roman.eot?#iefix);src:url(/designsystem-cdn/fonts/HelveticaNeueLTW01-55Roman.eot?#iefix) format("eot"),url(/designsystem-cdn/fonts/HelveticaNeueLTW01-55Roman.woff2) format("woff2");font-style:normal;font-display:swap}@font-face{font-family:HelveticaNeue;src:url(/designsystem-cdn/fonts/HelveticaNeueLTW01-55Roman.eot?#iefix);src:url(/designsystem-cdn/fonts/HelveticaNeueLTW01-55Roman.eot?#iefix) format("eot"),url(/designsystem-cdn/fonts/HelveticaNeueLTW01-55Roman.woff2) format("woff2");font-weight:400;font-style:normal;font-display:swap}@font-face{font-family:HelveticaNeue;src:url(/designsystem-cdn/fonts/HelveticaNeueLTW01-56Italic.eot?#iefix);src:url(/designsystem-cdn/fonts/HelveticaNeueLTW01-56Italic.eot?#iefix) format("eot"),url(/designsystem-cdn/fonts/HelveticaNeueLTW01-56Italic.woff2) format("woff2");font-weight:400;font-style:italic;font-display:swap}@font-face{font-family:HelveticaNeue;src:url(/designsystem-cdn/fonts/HelveticaNeueLTW01-65Medium.eot?#iefix);src:url(/designsystem-cdn/fonts/HelveticaNeueLTW01-65Medium.eot?#iefix) format("eot"),url(/designsystem-cdn/fonts/HelveticaNeueLTW01-65Medium.woff2) format("woff2");font-weight:500;font-style:normal;font-display:swap}@font-face{font-family:HelveticaNeue;src:url(/designsystem-cdn/fonts/HelveticaNeueLTW01-65Medium.eot?#iefix);src:url(/designsystem-cdn/fonts/HelveticaNeueLTW01-65Medium.eot?#iefix) format("eot"),url(/designsystem-cdn/fonts/HelveticaNeueLTW01-65Medium.woff2) format("woff2");font-weight:600;font-style:normal;font-display:swap}@font-face{font-family:HelveticaNeue;src:url(/designsystem-cdn/fonts/HelveticaNeueLTW01-75Bold.eot?#iefix);src:url(/designsystem-cdn/fonts/HelveticaNeueLTW01-75Bold.eot?#iefix) format("eot"),url(/designsystem-cdn/fonts/HelveticaNeueLTW01-75Bold.woff2) format("woff2");font-weight:700;font-style:normal;font-display:swap}@font-face{font-family:HelveticaNeue;src:url(/designsystem-cdn/fonts/HelveticaNeueLTW01-75Bold.eot?#iefix);src:url(/designsystem-cdn/fonts/HelveticaNeueLTW01-75Bold.eot?#iefix) format("eot"),url(/designsystem-cdn/fonts/HelveticaNeueLTW01-75Bold.woff2) format("woff2");font-weight:800;font-style:normal;font-display:swap}@font-face{font-family:HelveticaNeue;src:url(/designsystem-cdn/fonts/HelveticaNeueLTW01-75Bold.eot?#iefix);src:url(/designsystem-cdn/fonts/HelveticaNeueLTW01-75Bold.eot?#iefix) format("eot"),url(/designsystem-cdn/fonts/HelveticaNeueLTW01-75Bold.woff2) format("woff2");font-weight:900;font-style:normal;font-display:swap}@font-face{font-family:HelveticaNeue;src:url(/designsystem-cdn/fonts/HelveticaNeueLTW01-75Bold.eot?#iefix);src:url(/designsystem-cdn/fonts/HelveticaNeueLTW01-75Bold.eot?#iefix) format("eot"),url(/designsystem-cdn/fonts/HelveticaNeueLTW01-75Bold.woff2) format("woff2");font-weight:700;font-style:normal;font-display:swap}body.overflow-hidden{overflow:hidden;position:fixed;width:100%}#recommendation-overlay-content{margin-top:16px}.border-bottom{border-bottom:1px solid #dcdcdc}.hidden{display:none}.loading-wheel-sm.hidden{display:none}.contents{margin:0 auto}.pdp-alert .pdp-banners{z-index:9004}.pdp-main{padding-top:10px}.pdp-main .c-section{margin-top:0}.headerMiddleContent{width:100%;flex-grow:3;flex-shrink:1;flex-basis:100%}#header-offer-bar{position:relative;background:#fff;z-index:81}header .dm-dynamic-offer.dm-img-bkg.cmp-teaser{border:none;position:inherit}header .main-header-container .info-container ul li.account .create-account .loyalty-text{font-weight:700}header .main-header-container .info-container ul li.account .create-account .loyalty-text a{color:#222;font-size:14px;line-height:22px}header .info-container #notification-dd .c-loader{margin:125px 200px}header .info-container #cart-sidebar .c-loader{margin:300px 200px}body.has-messaging-bar header{top:35px}.header-separator{height:0}header{width:100%;border-bottom:1px solid #dcdcdc;position:fixed;background-color:#fff;font-size:14px;line-height:22px;top:0;left:0;right:0;z-index:80}header #dr-activity-banner{background:#fff;color:red;background-color:#ff0;font-weight:600;width:100%;font-size:12px;text-align:center;z-index:80;border-bottom:1px solid #ccc;top:0;left:0;right:0}header #dr-activity-banner .dr-activity-message{display:inline-block;padding:0 2px}header #messagingBar{background:#fff;color:#666;width:100%;line-height:35px;height:35px;font-size:15px;text-align:left;z-index:80;border-bottom:1px solid #ccc;top:0;left:0;right:0;position:fixed}header #messagingBar .messaging-bar-snippet{overflow:auto;display:inline-block;padding:0 2px}header #messagingBar .messaging-bar-snippet img{height:24px;width:auto;margin-top:-2px}header #messagingBar .container{width:1408px}header .main-header-container{max-width:1440px;margin:auto;padding:0 24px;display:flex;align-items:center;justify-content:center;height:60px;position:relative}header .scms-container{max-width:1440px;margin:auto;padding:8px 24px 0;line-height:26px;color:#70707a}header .scms-container span{padding-right:12px;margin-right:6px;border-right:#222 solid 1px}header .nav-container{margin-left:auto;display:flex;align-self:center;min-width:186px;flex-grow:1;flex-shrink:1;flex-basis:0;transition:min-width .2s ease;padding:0;background:#fff}header .nav-container span:focus-visible{outline:2px solid #802eff}header .nav-container .hamburger-btn{position:relative;width:32px;height:32px;margin-right:18px;margin-top:12px;border:3px solid #fff}header .nav-container .hamburger-btn .icon{position:absolute;height:3px;width:24px;top:12px;left:1px;background-color:#222;display:inline-block}header .nav-container .hamburger-btn .icon:before{transition-duration:.5s;position:absolute;width:24px;height:3px;background-color:#222;content:"";top:-8px}header .nav-container .hamburger-btn .icon:after{transition-duration:.5s;position:absolute;width:24px;height:3px;background-color:#222;content:"";top:8px}header .nav-container .hamburger-btn:hover{cursor:pointer}header .nav-container .hamburger-btn:focus-visible{outline:2px solid #802eff}header .nav-container .logo{width:fit-content;height:fit-content}header .nav-container .logo:focus-visible{outline:2px solid #802eff}header .nav-container .logo svg{width:114px;margin-top:-2px}header .nav-container .logo img{max-width:117px;width:100%;max-height:42px;height:auto;margin-top:12px;margin-left:-8px}header .nav-container .mega-nav{background-color:#fff;padding:0 54px;position:fixed;top:0;left:0;bottom:0;visibility:hidden;transform:translate(-110%);z-index:998;transition:.5s;max-width:380px;overflow:auto;width:100%}header .nav-container .mega-nav.open .account-dd{display:none}header .nav-container .mega-nav.open .sign-out{display:none}header .nav-container .mega-nav .main-nav,header .nav-container .mega-nav .sign-out,header .nav-container .mega-nav .support{display:block}header .nav-container .mega-nav .create-account .display-4{display:inline-block}header .nav-container .mega-nav.account-open .main-nav,header .nav-container .mega-nav.account-open .sign-out,header .nav-container .mega-nav.account-open .support{display:none}header .nav-container .mega-nav.account-open .create-account .display-4{display:none}header .nav-container .mega-nav.account-open .account-dd #sidenav-account-details{display:inline-block}header .nav-container .mega-nav.account-open .account-dd #sidenav-account-details ul{padding-inline-start:0}header .nav-container .mega-nav.account-open .account-dd #sidenav-account-details ul li a{padding-top:16px;font-weight:400;font-size:16px;line-height:26px;color:#1b1b1d}header .nav-container .mega-nav.account-open .account .create-account .sidenav-myaccount a{font-weight:500;font-size:22px;line-height:28px;color:#222;position:relative}header .nav-container .mega-nav.account-open .account .create-account .sidenav-myaccount .arrow{width:16px;position:absolute;left:-32px;top:12px;display:inline-block;height:2px;background-color:#222}header .nav-container .mega-nav.account-open .account .create-account .sidenav-myaccount .arrow::after,header .nav-container .mega-nav.account-open .account .create-account .sidenav-myaccount .arrow::before{content:"";position:absolute;width:12px;height:2px;left:-1px;background-color:#222;z-index:-1}header .nav-container .mega-nav.account-open .account .create-account .sidenav-myaccount .arrow::after{top:-4px;transform:rotate(-45deg)}header .nav-container .mega-nav.account-open .account .create-account .sidenav-myaccount .arrow::before{top:4px;transform:rotate(45deg)}header .nav-container .mega-nav .close{top:24px;right:24px}header .nav-container .mega-nav .close:hover{cursor:pointer}header .nav-container .mega-nav a{text-decoration:none;color:#222;display:block}header .nav-container .mega-nav a:active,header .nav-container .mega-nav a:hover{text-decoration:underline;cursor:pointer}header .nav-container .mega-nav .account{margin-top:36px}header .nav-container .mega-nav .account .user-name{font-weight:100;font-size:30px;line-height:38px;color:#2b2b30;margin-bottom:29px}header .nav-container .mega-nav .account .my-account{font-weight:400;font-size:16px;line-height:26px;padding-bottom:12px;color:#1b1b1d}header .nav-container .mega-nav .account .create-account{padding:14px 0}header .nav-container .mega-nav .account .create-account li{padding-bottom:16px}header .nav-container .mega-nav .account .create-account .sidenav-myaccount a{font-weight:400;font-size:16px;color:#1b1b1d}header .nav-container .mega-nav .account .create-account a{font-weight:400;font-size:14px;line-height:26px;padding-bottom:16px;display:inline;color:#0071d0}header .nav-container .mega-nav .account .create-account ul{list-style:none;margin:0}header .nav-container .mega-nav .account .create-account.open .my-account-text{font-weight:500;font-size:22px;line-height:28px}header .nav-container .mega-nav .main-nav{font-weight:500;font-size:22px;line-height:28px;list-style-type:none;margin-left:0;padding-inline-start:0;margin-block-start:0;margin-top:0}header .nav-container .mega-nav .main-nav-item{padding:16px 0;line-height:22px}header .nav-container .mega-nav .main-nav-item.create-account{margin-top:-45px}header .nav-container .mega-nav .main-nav-item.create-account .arrow{display:none}header .nav-container .mega-nav .main-nav-item.create-account .title{font-weight:400;font-size:16px;line-height:26px}header .nav-container .mega-nav .main-nav-item a:active,header .nav-container .mega-nav .main-nav-item a:visited{color:#54545c}header .nav-container .mega-nav .main-nav-item:hover{cursor:pointer}header .nav-container .mega-nav .main-nav-item.open{padding:0 36px;margin-left:-36px;margin-top:24px;padding-right:0;padding-bottom:14px}header .nav-container .mega-nav .main-nav-item.open .arrow{width:16px;position:absolute;left:16px;top:90px;display:inline-block;height:2px;background-color:#222}header .nav-container .mega-nav .main-nav-item.open .arrow::after,header .nav-container .mega-nav .main-nav-item.open .arrow::before{content:"";position:absolute;width:12px;height:2px;left:-1px;background-color:#222;z-index:-1}header .nav-container .mega-nav .main-nav-item.open .arrow::after{top:-4px;transform:rotate(-45deg)}header .nav-container .mega-nav .main-nav-item.open .arrow::before{top:4px;transform:rotate(45deg)}header .nav-container .mega-nav .sub-nav{transform:translate(0,0);animation:delayedFadeIn .4s;visibility:hidden;display:none;font-weight:400;font-size:16px;line-height:42px;list-style-type:none;padding-inline-start:0;position:absolute;background-color:#fff;margin:24px 24px 24px 0;padding-right:24px;z-index:-1;padding-bottom:42px}header .nav-container .mega-nav .sub-nav li a{line-height:22px;padding:10px 0}header .nav-container .mega-nav .sub-nav .popular-image{height:74px;width:112px;object-fit:cover;display:inline-block}header .nav-container .mega-nav .sub-nav .see-all{margin-bottom:36px;position:absolute;color:#0071d0!important;max-width:290px}header .nav-container .mega-nav .sub-nav .see-all a{color:inherit}header .nav-container .mega-nav .sub-nav .see-all .right-arrow{position:absolute;height:3px;width:16px;bottom:18px;margin-left:15px;background-color:#0071d0}header .nav-container .mega-nav .sub-nav .see-all .right-arrow::after,header .nav-container .mega-nav .sub-nav .see-all .right-arrow::before{content:"";position:absolute;width:11px;height:3px;right:-4px;background-color:#0071d0}header .nav-container .mega-nav .sub-nav .see-all .right-arrow::after{top:-3px;transform:rotate(45deg)}header .nav-container .mega-nav .sub-nav .see-all .right-arrow::before{top:3px;transform:rotate(-45deg)}header .nav-container .mega-nav .sign-out{margin-bottom:142px;margin-top:24px}header .nav-container .mega-nav .sign-out a{color:#0071d0}header .nav-container .mega-nav.open .account{overflow:hidden;animation:fadeIn .5s}header .nav-container .mega-nav.open li{display:none}header .nav-container .mega-nav.open li.open{display:block}header .nav-container .mega-nav.open li.open .sub-nav{visibility:visible;display:block;animation:delayedFadeIn 1.2s ease-in}header .nav-container .mega-nav.open li.open .sub-nav li{display:block}header .nav-container .mega-nav.open li.open .sub-nav li.popular{display:flex;align-items:center}header .nav-container .mega-nav.open .main-nav{border-bottom:1px solid #dcdcdc;padding-left:36px;margin-left:-36px}header .nav-container .mega-nav .support{font-weight:400;font-size:16px;line-height:26px;list-style-type:none;margin-left:0;margin-top:0;padding-inline-start:0;margin-block-end:0;max-width:280px}header .nav-container .mega-nav .support li{margin-top:16px}header .nav-container.open .mega-nav{transform:translate(0);visibility:visible;box-shadow:0 18px 18px rgba(0,0,0,.3)}header .search-container{align-self:center;padding:16px;display:flex;position:relative;width:100%}header .search-container .search-layout{padding:16px 36px;width:100%;display:none}header .search-container .search .search-button{border-radius:0 3px 3px 0;margin:0;text-align:center;filter:none;outline:0;border:none;height:50px;width:100px;background:#4a4a4a}header .search-container .search .search-button:hover{cursor:pointer}header .search-container .search-icon{width:30px;position:absolute;right:12px;top:4px}header .search-container .search-icon:hover{cursor:pointer}header .search-container .search-icon .cls-1{fill:#54545c}header .search-container.open .search{display:block;visibility:visible;opacity:1;position:fixed;z-index:1000;top:0;left:0;height:100%;width:100%;background-color:#fff;animation:fadeIn .5s}header .search-container.open .search-layout{padding:16px 36px;display:block}header .search-container .close{display:none}header .info-container{position:relative;width:auto;opacity:1;flex-grow:1;flex-shrink:1;flex-basis:0}header .info-container a{color:#222;cursor:pointer}header .info-container ul{list-style-type:none;display:flex;padding-inline-start:0;align-items:center;justify-content:center;margin:0}header .info-container ul li{display:inline-block;padding:0 12px;width:max-content}header .info-container ul li.order-status{display:none}header .info-container ul li.quick-order{display:none}header .info-container ul li.cart{margin-right:-16px}header .info-container ul li.cart a{height:42px;width:42px;display:inline-block;margin-left:-2px}header .info-container ul li.cart a svg{height:32px;width:32px;display:inline-block}header .info-container ul li.bell,header .info-container ul li.cart{width:52px;margin-bottom:-10px;position:relative}header .info-container ul li.bell:hover,header .info-container ul li.cart:hover{cursor:pointer}header .info-container ul li.bell.active,header .info-container ul li.cart.active{border-bottom:3px solid #e71316;margin-bottom:-13px}header .info-container ul li.bell a:focus,header .info-container ul li.cart a:focus{outline:0}header .info-container ul li.bell .cls-1,header .info-container ul li.cart .cls-1{fill:#54545c}header .info-container ul li.bell .alert,header .info-container ul li.cart .alert{border-radius:50%;background-color:#e71316;border:#fff solid 1px;position:absolute;display:inline-block;height:12px;width:12px;right:12px;padding:0}header .info-container ul li.bell .count,header .info-container ul li.cart .count{color:#e71316;font-size:11px;font-weight:700;position:absolute;display:inline-block;right:19px;top:-11px}header .info-container ul li.bell{margin-bottom:-8px}header .info-container ul li.account{display:none;position:relative;margin-bottom:-2px}header .info-container ul li.account:hover{cursor:pointer}header .info-container ul li.account.open::after{content:" ";position:absolute;bottom:-3px;height:3px;background-color:#e71316;width:100%;left:0;z-index:83}header .info-container ul span#logged-in-toggle::after,header .info-container ul span#sign-in-toggle::after{content:"▼";font-size:8px;margin-left:6px;display:inline-block;color:#54545c}header .info-container .cart-dd{transform:translate(110%);transition:.5s;visibility:hidden;position:fixed;z-index:1000;background-color:#fff;right:0;top:0;width:100%;height:100%;max-width:440px;overflow-y:scroll;padding:32px 24px;overscroll-behavior:contain}header .info-container .cart-dd-header{font-weight:500;font-size:22px;line-height:28px;color:#1b1b1d}header .info-container .cart-dd-header .close{right:16px;top:24px}header .info-container .cart-dd-body .lable{margin-top:32px;font-weight:500;font-size:18px;line-height:22px}header .info-container .cart-dd-body .product{font-weight:400;margin-top:24px}header .info-container .cart-dd-body .product .image{height:50px;width:50px;background-color:#a2a2a2;display:inline-block;float:left}header .info-container .cart-dd-body .product .info{width:100%;padding-left:66px;font-weight:400}header .info-container .cart-dd-body .product .info .title a{font-weight:400;font-size:14px;line-height:20px;color:#0071d0}header .info-container .cart-dd-body .product .info .bold{font-weight:600}header .info-container .cart-dd-body .product .info .contactUsLink{color:#0071d0}header .info-container .cart-dd-body .product .info .special-offer-wrapper{margin-top:8px}header .info-container .cart-dd-body .product .info .special-offer-wrapper .finalPrice{font-size:16px;font-weight:500}header .info-container .cart-dd-body .product .info .special-offer-wrapper .strikeThroughPrice{margin-left:5px;color:#70707a}header .info-container .cart-dd-body .product .info .special-offer-wrapper .absoluteSave{color:#01891e;font-weight:500;font-size:12px}header .info-container .cart-dd-body .product .info .special-offer-wrapper .specialOfferEndDate{color:#70707a;font-weight:500;font-size:12px}header .info-container .cart-dd-body .product .info .special-offer-wrapper .tooltip{position:relative;display:inline-block}header .info-container .cart-dd-body .product .info .special-offer-wrapper .tooltip .icon-wrapper{display:inline-block;margin-left:5px}header .info-container .cart-dd-body .product .info .special-offer-wrapper .tooltip .tooltiptext{display:block;visibility:hidden;position:absolute;top:100%;left:50%;transform:translate(-50%,10px);width:max-content;max-width:220px;background-color:#fff;border:1px solid #ddd;border-radius:3px;color:#000;padding:10px;text-align:center;z-index:1;opacity:0;transition:opacity .3s;box-shadow:0 6px 8px 0 rgba(13,13,13,.1)}header .info-container .cart-dd-body .product .info .special-offer-wrapper .tooltip .tooltiptext::before{content:"";position:absolute;top:-9px;left:calc(50% - 5px);border-left:1px solid #ddd;border-top:1px solid #ddd;transform:rotate(45deg);width:16px;height:16px;background:#fff}header .info-container .cart-dd-body .product .info .special-offer-wrapper .tooltip .tooltiptext .signInLink{color:#0071d0}header .info-container .cart-dd-body .product .info .special-offer-wrapper .tooltip:hover .tooltiptext{visibility:visible;opacity:1}header .info-container .cart-dd-footer .subtotal{font-weight:500;font-size:18px;line-height:28px}header .info-container .cart-dd-footer .price{font-weight:200;font-size:22px}header .info-container .cart-dd-footer a{display:inline-block;color:#0071d0}header .info-container .cart-dd-footer .offer{box-shadow:0 2px 4px rgba(34,34,34,.1)}header .info-container .cart-dd-footer .offer #recommendation-overlay{position:fixed;display:none;background:#fff;top:0;padding:16px;right:0;left:0;z-index:1;height:100vh;min-height:1200px}header .info-container .cart-dd-footer .offer #recommendation-overlay.open{display:block}header .info-container .cart-dd-footer .offer #recommendation-overlay .back{font-weight:500;font-size:14px;line-height:22px;color:#0071d0;margin-bottom:24px;padding-left:18px}header .info-container .cart-dd-footer .offer #recommendation-overlay .back .arrow{width:12px;position:absolute;left:16px;top:26px;display:inline-block;height:2px;background-color:#0071d0}header .info-container .cart-dd-footer .offer #recommendation-overlay .back .arrow::after,header .info-container .cart-dd-footer .offer #recommendation-overlay .back .arrow::before{content:"";position:absolute;width:9px;height:2px;left:-1px;background-color:#0071d0;z-index:-1}header .info-container .cart-dd-footer .offer #recommendation-overlay .back .arrow::before{top:3px;transform:rotate(45deg)}header .info-container .cart-dd-footer .offer #recommendation-overlay .back .arrow::after{top:-3px;transform:rotate(-45deg)}header .info-container .cart-dd-footer .offer #recommendation-overlay .back:hover{cursor:pointer}header .info-container .cart-dd-footer .offer #recommendation-overlay a.button.btn-featured{color:#fff;line-height:40px;padding:0 16px;background-color:#e71316;border:1px solid #e71316;border-radius:3px}header .info-container .cart-dd-footer .suggested-products{background-color:#f7f7f7;padding:24px;margin:0 -24px}header .info-container .cart-dd-footer .suggested-products .title{font-weight:400;font-size:16px;line-height:20px;margin-bottom:16px}header .info-container .cart-dd-footer .suggested-products .product{background:#fff;border:1px solid #e5e5e5;border-radius:3px;padding:16px}header .info-container .cart-dd-footer .suggested-products .product .line{display:flex;align-items:center;justify-content:space-between;flex-direction:row}header .info-container .cart-dd-footer .suggested-products .product .line .image{width:50px;height:auto}header .info-container .cart-dd-footer .suggested-products .product .line .image img{max-width:100%;max-height:100%}header .info-container .cart-dd-footer .suggested-products .product .line .label{padding:0 16px;font-weight:700;font-size:14px;line-height:22px;color:#008ceb;width:100%;white-space:inherit;background-color:#fff}header .info-container .cart-dd-footer .suggested-products .product .line .qty{min-width:80px;text-align:right}header .info-container .cart-dd-footer .suggested-products .product .line .qty span{font-weight:400;font-size:14px;line-height:12px;text-align:center;color:#54545c;padding-right:8px}header .info-container .cart-dd-footer .suggested-products .product .line .qty input{background:#fff;border:1px solid #dcdcdc;border-radius:3px;width:34px;height:34px}header .info-container .cart-dd-footer .suggested-products .product .description{font-weight:400;font-size:12px;line-height:15px;color:#61616b;padding:4px 0}header .info-container .cart-dd-footer .suggested-products .product .info{display:flex;justify-content:space-between}header .info-container .cart-dd-footer .suggested-products .product .info .price{font-weight:200;font-size:14px;line-height:22px}header .info-container .cart-dd-footer .suggested-products .product .info .cmp-p-ctaitem{margin-top:-12px}header .info-container .cart-dd-footer .suggested-products .product .info .cmp-p-ctaitem.m--small .cmp-ctaitem{padding:0 16px}header .info-container .cart-dd-footer .cmp-p-ctaitem.m--block .cmp-ctaitem .shopping--btn{color:#0071d0;width:100%;display:block}header .info-container .cart-dd-footer .cmp-p-ctaitem.m--block .cmp-ctaitem__anchor{width:100%}header .info-container .cart-dd-footer .cmp-p-ctaitem.m--block .cmp-ctaitem{padding:0}header .info-container .cart-dd .float-right{float:right}header .info-container .cart-dd .no-product{text-align:center;color:#000;padding:72px 0}header .info-container .cart-dd.open{transform:translate(0);visibility:visible}header .info-container .bell-dd{overflow-y:scroll;box-shadow:0 4px 6px rgba(0,0,0,.1);background-color:#fff;overscroll-behavior:contain}header .info-container .bell-dd a{color:#0071d0}header .info-container .bell-dd-header{font-weight:500;font-size:22px;line-height:28px;padding:63px 36px 16px;border-bottom:1px solid #dcdcdc;background-color:#fff}header .info-container .bell-dd-header a{font-weight:400;font-size:14px;line-height:22px;display:inline;float:right;padding-top:4px}header .info-container .bell-dd-body .notification{padding:36px 36px 36px;font-weight:200;font-size:14px;line-height:22px;border-bottom:1px solid #dcdcdc;background-color:#fff}header .info-container .bell-dd-body .notification .body{position:relative}header .info-container .bell-dd-body .notification.new{background-color:#f7f7f7}header .info-container .bell-dd-body .notification .label{font-weight:700;font-size:12px;line-height:22px;color:#81828c;padding:0 0 6px 0;display:block;background-color:transparent}header .info-container .bell-dd-body .notification .time{font-weight:400;font-size:12px;line-height:22px;float:right}header .info-container .bell-dd-body .notification a{display:inline}header .info-container .bell-dd-body .notification a .label:hover{text-decoration:none}header .info-container .bell-dd-body .notification a .body{padding-right:30px;position:relative;color:#1b1b1d}header .info-container .bell-dd-body .notification a .body:hover{color:#0071d0;text-decoration:underline;cursor:pointer}header .info-container .bell-dd-body .notification .bin{width:20px;position:absolute;top:0;right:0;fill:#92929e}header .info-container .bell-dd-footer{font-weight:500;font-size:14px;line-height:22px}header .info-container .bell-dd.open{display:block;visibility:visible;opacity:1;position:fixed;z-index:1000;height:100%;width:100%;top:0;left:0;right:0;animation:fadeIn .5s}header .bell-dd,header .search{display:none;visibility:hidden;opacity:0}header .account-dd #sidenav-account-details{display:none}header .account-dd .open #sidenav-account-details{display:inline-block}header .close{position:absolute;right:36px;top:20px;width:42px;height:42px;opacity:1}header .close:hover{opacity:.5}header .close:before{transform:rotate(45deg)}header .close:after{transform:rotate(-45deg)}header .close:after,header .close:before{position:absolute;left:20px;content:" ";height:24px;width:3px;background-color:#1b1b1d;transition:visibility 0s,opacity .5s linear}header.open .full-bg{opacity:1;visibility:visible;display:block}header .full-bg{opacity:0;visibility:hidden;display:none;position:fixed;content:"";z-index:81;top:0;left:0;width:100%;height:100%;background-color:rgba(0,0,0,.5);transition:visibility 0s,opacity .5s linear}header .full-bg.open{opacity:1;visibility:visible;display:block}header .full-bg.open-top{top:112px}header .search-bg{opacity:0;visibility:hidden;display:none;position:fixed;content:"";z-index:81;left:0;width:100%;height:100%;background-color:rgba(0,0,0,.5);transition:visibility 0s,opacity .5s linear}header .search-bg.open{opacity:1;visibility:visible;display:block}header .c-alert{position:relative;display:inline-block;padding:24px 16px 24px 42px;color:#222;border:1px solid #dcdcdc;margin-top:32px}header .c-alert--warning{border-left:8px solid #f76c1f}header .c-alert__title{font-size:16px;padding-right:6px;font-weight:900}header .c-alert__desc{font-size:16px}header .c-alert__icon{width:24px;height:24px;position:absolute;left:12px}header a:hover{text-decoration:underline}@media (min-width:576px){header .info-container .bell-dd-header{padding:63px 76px 16px}header .info-container .bell-dd-body .notification{padding:36px 76px 36px}}@media (min-width:768px){header .info-container .bell-dd-header{padding:63px 146px 16px}header .info-container .bell-dd-body .notification{padding:36px 146px 36px}}@media (min-width:992px){header.project-header{z-index:0}header .main-header-container{height:76px}header .main-header-container .nav-container .mega-nav .close{top:24px;right:24px}header .main-header-container .search-container .search-layout{margin-right:0}header .main-header-container .info-container{width:100%}header .main-header-container .info-container ul li.order-status{display:inline-block}header .main-header-container .info-container ul li.quick-order{display:inline-block}header .main-header-container .info-container ul li.account{display:inline-block}header .main-header-container .info-container ul li.account .sing-out a{color:#0071d0}header .main-header-container .info-container ul li.account .create-account .loyalty-text{font-weight:700}header .main-header-container .info-container ul li.account .create-account .loyalty-text a{color:#222;font-size:14px;line-height:22px}header .main-header-container .info-container ul li.account .create-account a{display:inline;color:#0071d0}header .main-header-container .info-container ul li.account .create-account ul li a{color:#1b1b1d}header .main-header-container .info-container ul li.account .create-account .sing-out a{color:#0071d0}header .main-header-container .info-container ul li.account .create-account .points{margin-top:-10px}header .main-header-container .info-container ul li.account .create-account .points a{color:#70707a;font-size:14px;line-height:22px}header .main-header-container .info-container ul li.account.open .account-dd{display:inline-block;padding:36px;top:27px;right:-2px;height:auto;overflow-y:scroll;max-height:80vh;overflow-x:hidden;overscroll-behavior:contain}header .main-header-container .info-container ul li.account.open .account-dd ul{display:block;padding-left:0;font-size:16px;line-height:26px;margin-left:-10px}header .main-header-container .info-container ul li.account.open .account-dd ul li{padding-top:8px;display:block;width:auto}header .main-header-container .info-container ul li.account.active{border-bottom:3px solid #e71316;margin-bottom:-7px}header .main-header-container .info-container ul li.cart{margin-right:-16px}header .main-header-container .search .close{opacity:0}header .main-header-container.open .info-container{width:0;opacity:0;flex-grow:0}header .main-header-container.open .info-container ul{pointer-events:none}header .main-header-container.open .nav-container{min-width:152px;transition:min-width .2s ease}header .main-header-container.open .nav-container .menu{width:0}header .main-header-container.open .nav-container .menu .icon{display:none}header .main-header-container.open .search-container{width:100%;margin-right:48px}header .main-header-container.open .search-layout{margin-right:32px}header .main-header-container.open .close{display:inline-block;position:absolute;right:0;animation:delayedFadeIn .7s;opacity:1;z-index:1001;padding:10px;margin-left:5px}header .main-header-container.open .close:hover{opacity:.5;cursor:pointer}header .main-header-container.open .close:focus-visible{outline:2px solid #802eff}header .nav-container .logo svg{width:136px;height:76px;margin-top:-8px}header .nav-container .logo svg .tf-logo-cls-1{fill:#e71316}header .nav-container .logo svg .tf-logo-cls-2{fill:#fff}header .nav-container .logo img{max-width:140px;width:100%;max-height:46px;height:auto;margin-top:12px;margin-left:0}header .nav-container .logo .scms{margin-top:10px;width:150px;margin-left:-8px}header .nav-container .hamburger-btn{margin-top:20px}header .nav-container .mega-nav{padding:0 74px 0 74px;overflow-x:hidden;min-width:380px}header .nav-container .mega-nav span:focus-visible{outline:2px solid #802eff}header .nav-container .mega-nav .main-nav{margin-top:24px}header .nav-container .mega-nav .main-nav-item{display:block;width:308px}header .nav-container .mega-nav .main-nav-item:hover{color:#005daa}header .nav-container .mega-nav .main-nav-item.open{border-bottom:1px solid #dcdcdc;border-top:1px solid #dcdcdc;background-color:#fff;display:block;padding:15px 0;margin-left:0;margin-top:0;padding-right:16px;padding-bottom:14px}header .nav-container .mega-nav .main-nav-item.open::after{content:"";display:block!important;position:absolute;top:0;right:0;border-right:2px solid #fff;height:100%}header .nav-container .mega-nav .main-nav-item.open .sub-nav{left:380px;top:36px;background-color:#fff;padding:0 42px;border-left:1px solid #dcdcdc;visibility:visible;transform:translate(0);display:block;margin-left:0;padding-bottom:42px}header .nav-container .mega-nav .main-nav-item.open .sub-nav li{display:block}header .nav-container .mega-nav .main-nav-item.open .arrow,header .nav-container .mega-nav .main-nav-item.open::after,header .nav-container .mega-nav .main-nav-item.open::before{display:none}header .nav-container .mega-nav .main-nav-item.open .main-nav{border-bottom:none;padding-left:0;margin-left:0}header .nav-container .mega-nav.open{min-width:760px}header .nav-container .mega-nav.open li{display:block}header .nav-container .mega-nav.open .account{max-height:0;transition:max-height .15s ease-out;overflow:hidden;animation:fadeIn .5s}header .nav-container .mega-nav.open .main-nav{border-bottom:none;width:340px}header .nav-container .mega-nav.close .pragma-toggle:hover{cursor:pointer}header .nav-container .mega-nav.close:hover{cursor:pointer}header .nav-container .mega-nav .account{display:none}header .nav-container .mega-nav .support .dt-hide{display:none}header .nav-container .mega-nav .sign-out{border-top:none}header .nav-container .mega-nav .sign-out a{display:none}header .nav-container .mega-nav .logo img{margin-top:32px;max-width:142px;margin-left:0}header .info-container .bell-dd{border:1px solid #d8d8d8;border-radius:4px;background-color:#fff}header .info-container .bell-dd-header{padding:18px 26px 16px 28px;color:#1b1b1d}header .info-container .bell-dd-header .close{display:none}header .info-container .bell-dd-body .notification{padding:24px;font-size:14px;line-height:22px;font-weight:400}header .info-container .bell-dd-body .notification .label{color:#54545c}header .info-container .bell-dd-body .notification .body{color:#1b1b1d;position:relative}header .info-container .bell-dd-body .notification.new:hover .body{color:#0071d0;text-decoration:underline;cursor:pointer}header .info-container .bell-dd-footer{padding:24px}header .info-container .bell-dd.open{position:absolute;top:36px;left:auto;right:32px;height:auto;max-height:calc(100vh - 140px);width:420px}header .info-container .account-dd{position:absolute;width:330px;background:#fff;border:1px solid #d8d8d8;box-sizing:border-box;box-shadow:0 4px 6px rgba(0,0,0,.1);border-radius:4px;display:none;z-index:999}header .info-container .account-dd .account{padding-left:0;padding-right:0;text-align:left}header .info-container .account-dd .create-account .display-4{word-break:break-all;border-bottom:1px solid #dcdcdc}header .search-container{align-self:center;position:relative;transition:1s}header .search-container .search{display:block;visibility:visible;opacity:1;width:100%;padding:0;height:50px}header .search-container .search-layout{display:flex;padding:0}header .search-container .search-icon{display:none}header .account-dd #sidenav-account-details{display:inline-block}header .search-bg{top:96px}header body.has-messaging-bar{top:112px}}@media (prefers-reduced-motion){.hamburger-btn{animation:none!important}.logo{animation:none!important}}.mega-nav{animation:none!important}@keyframes fadeIn{0%{opacity:0;display:none}100%{opacity:1;display:block}}@keyframes fadeOut{0%{opacity:1}100%{opacity:0}}@keyframes delayedFadeIn{0%{display:none;opacity:0}80%{display:block;opacity:1}}.sr-only{display:none}#notification-body .body{position:relative}#notification-body .content{padding:0 20px 0 0!important;display:inline-block}footer,header{font-family:HelveticaNeue,sans-serif;-ms-text-size-adjust:100%;-webkit-text-size-adjust:100%;max-width:100%;scroll-behavior:smooth;color:#1b1b1d;margin:0}footer *,header *{-webkit-box-sizing:border-box;-moz-box-sizing:border-box;box-sizing:border-box}footer :after,footer :before,header :after,header :before{-webkit-box-sizing:border-box;-moz-box-sizing:border-box;box-sizing:border-box}footer :focus-visible,header :focus-visible{outline:2px solid #802eff}footer input:focus-visible,header input:focus-visible{outline:0}footer .bold-label,header .bold-label{font-weight:700}footer .h1,footer .h2,footer .h3,footer .h4,footer .h5,footer .h6,footer body,footer h1,footer h2,footer h3,footer h4,footer h5,footer h6,header .h1,header .h2,header .h3,header .h4,header .h5,header .h6,header body,header h1,header h2,header h3,header h4,header h5,header h6{color:#222}footer .text-light,footer .text-light .display-1,footer .text-light .display-2,footer .text-light .display-3,footer .text-light .display-4,footer .text-light .h1,footer .text-light .h2,footer .text-light .h3,footer .text-light .h4,footer .text-light .h5,footer .text-light .h6,footer .text-light body,footer .text-light h1,footer .text-light h2,footer .text-light h3,footer .text-light h4,footer .text-light h5,footer .text-light h6,header .text-light,header .text-light .display-1,header .text-light .display-2,header .text-light .display-3,header .text-light .display-4,header .text-light .h1,header .text-light .h2,header .text-light .h3,header .text-light .h4,header .text-light .h5,header .text-light .h6,header .text-light body,header .text-light h1,header .text-light h2,header .text-light h3,header .text-light h4,header .text-light h5,header .text-light h6{color:#fff}footer body,header body{margin:0;font-size:16px;line-height:26px}footer p,header p{margin-top:0;margin-bottom:0;font-size:16px;line-height:26px}footer .p-grey,header .p-grey{color:#54545c}footer .text-center,header .text-center{text-align:center}footer .alt,header .alt{font-size:16px;line-height:26px}footer .text-size-14,header .text-size-14{font-size:14px;line-height:22px}footer a,header a{text-decoration:none;color:#1b1b1d}footer a:hover,header a:hover{text-decoration:none;color:#1b1b1d}footer a:visited,header a:visited{text-decoration:none;color:#1b1b1d}footer .disabled,header .disabled{color:#a2a2a2}footer .label-medium,header .label-medium{color:#222;font-size:16px;line-height:26px;font-weight:400}footer .label-bold,header .label-bold{color:#222;font-size:16px;line-height:26px;font-weight:bolder}footer .hint,header .hint{font-size:14px;line-height:30.727268px}footer .blockquote,header .blockquote{color:#222;font-size:20.571424px;line-height:33.090902px;margin-bottom:0}footer .alt-color,header .alt-color{color:#54545c}footer .success,header .success{color:#3bad2f}footer .warning,header .warning{color:#ed7700}footer .error,header .error{color:#e71316}footer .thin,header .thin{font-weight:lighter}footer .light,header .light{font-weight:300}footer .italic,header .italic{font-style:italic}footer .medium,header .medium{font-weight:700}footer .bold,header .bold{font-weight:bolder}footer .h1,footer .h2,footer .h3,footer .h5,footer h1,footer h2,footer h3,footer h5,header .h1,header .h2,header .h3,header .h5,header h1,header h2,header h3,header h5{font-weight:400;margin:0;padding-bottom:10px}footer .h4,footer h4,header .h4,header h4{font-weight:600;margin:0;padding-bottom:10px}footer .h6,footer h6,header .h6,header h6{font-weight:400;margin:0;padding-bottom:10px}footer .display-1,footer .display-2,footer .display-3,footer .display-4,header .display-1,header .display-2,header .display-3,header .display-4{font-family:HelveticaNeueLight,Helvetica,Roboto,"Segoe UI",Arial,sans-serif;font-weight:lighter}footer .h1,footer h1,header .h1,header h1{font-size:32px;line-height:40px}footer .h2,footer h2,header .h2,header h2{font-size:26px;line-height:33px}footer .h3,footer h3,header .h3,header h3{font-size:22px;line-height:28px}footer .h4,footer h4,header .h4,header h4{font-size:20px;line-height:25px}footer .h5,footer h5,header .h5,header h5{font-size:18px;line-height:23px}footer .h6,footer h6,header .h6,header h6{font-size:16px;line-height:20px}footer .display-1,header .display-1{font-size:40px;line-height:50px}footer .display-2,header .display-2{font-size:32px;line-height:40px}footer .display-3,header .display-3{font-size:24px;line-height:30px}footer .display-4,header .display-4{font-weight:300;font-size:30px;line-height:38px}@media (max-width:768px){footer .h1,footer h1,header .h1,header h1{font-size:26px;line-height:33px}footer .h2,footer h2,header .h2,header h2{font-size:21px;line-height:26px}footer .h3,footer h3,header .h3,header h3{font-size:18px;line-height:23px}footer .h4,footer h4,header .h4,header h4{font-size:16px;line-height:20px}footer .h5,footer h5,header .h5,header h5{font-size:16px;line-height:20px}footer .h6,footer h6,header .h6,header h6{font-size:16px;line-height:20px}footer .display-1,header .display-1{font-size:40px;line-height:50px}footer .display-2,header .display-2{font-size:32px;line-height:40px}footer .display-3,header .display-3{font-size:24px;line-height:30px}footer .display-4,header .display-4{font-weight:300;font-size:30px;line-height:38px}}footer .font-size-14,header .font-size-14{font-size:14px}footer .font-size-16,header .font-size-16{font-size:16px}footer .font-size-18,header .font-size-18{font-size:18px}footer .font-size-20,header .font-size-20{font-size:20px}footer .font-size-22,header .font-size-22{font-size:22px}footer .font-size-24,header .font-size-24{font-size:24px}footer .font-size-26,header .font-size-26{font-size:26px}footer fieldset,header fieldset{display:block;margin-inline-start:0;margin-inline-end:0;padding-block-start:0;padding-inline-start:0;padding-inline-end:0;padding-block-end:0;border-width:0;border-style:none}@media print{footer .cmp-p-pageheadinghero,header .cmp-p-pageheadinghero{display:none}footer .cmp-p-manualnav,header .cmp-p-manualnav{display:none}footer .header-cmp,header .header-cmp{display:none}footer .cmp-p-anchorlist,header .cmp-p-anchorlist{display:none}footer .cmp-p-ctaitem,header .cmp-p-ctaitem{display:none}footer .footer,header .footer{display:none}footer .cmp-p-testimonial,header .cmp-p-testimonial{display:none}footer td,footer th,header td,header th{padding-top:4px;padding-bottom:4px;height:30px}}.cmp-ctaitem{margin-top:16px}.cmp-ctaitem__anchor{display:block;color:#0071d0;font-weight:700;font-size:18px}.cmp-ctaitem__anchor:hover{color:#005daa}.cmp-ctaitem__anchor:visited{color:#0071d0}.cmp-ctaitem__icon{float:right;width:24px}.cmp-ctaitem .modal-toggle{cursor:pointer}.cmp-p-ctaitem:hover{cursor:pointer}.cmp-p-ctaitem.m--center{text-align:center}.cmp-p-ctaitem.m--resource{border:1px solid #c9c8c8;border-radius:4px;padding:24px;display:block;font-weight:400;font-size:14px}.cmp-p-ctaitem.m--resource__anchor{display:block;text-decoration:none;color:#0071d0}.cmp-p-ctaitem.m--resource .cmp-ctaitem__icon{top:0;color:#c9c8c8}.cmp-p-ctaitem.m--video .cmp-ctaitem{display:inline-block;text-align:center;margin:0;height:40px;padding:0 24px 0 24px;margin-top:8px;width:auto}.cmp-p-ctaitem.m--video .cmp-ctaitem__anchor{color:#0071d0;font-weight:400}.cmp-p-ctaitem.m--video .cmp-ctaitem .cmp-ctaitem__icon{height:32px;width:32px;margin-top:-3px;border-radius:50%;background-color:#e71316;margin-left:18px;padding-top:5px;color:#fff}.cmp-p-ctaitem.m--btn-primary .cmp-ctaitem{display:inline-block;text-align:center;margin:0;border-radius:3px;font-weight:700;font-size:14px;height:40px;padding:0 24px 0 24px;box-sizing:border-box;line-height:40px;color:#222;width:auto;background-color:#e71316;border:solid 1px #e71316}.cmp-p-ctaitem.m--btn-primary .cmp-ctaitem__anchor{color:#fff;font-size:14px}.cmp-p-ctaitem.m--btn-primary .cmp-ctaitem:hover{background-color:#d01013;border:solid 1px #d01013;cursor:pointer}.cmp-p-ctaitem.m--btn-primary .cmp-ctaitem:active{box-shadow:inset 0 2px 5px 2px #d01013;background-color:#e71316}.cmp-p-ctaitem.m--btn-primary .cmp-ctaitem__icon{margin-top:8px;margin-left:8px}.cmp-p-ctaitem.m--btn-secondary .cmp-ctaitem{display:inline-block;text-align:center;margin:0;border-radius:3px;font-weight:700;font-size:14px;height:40px;padding:0 24px 0 24px;box-sizing:border-box;line-height:40px;color:#222;width:auto;background-color:#555759;border:solid 1px #555759}.cmp-p-ctaitem.m--btn-secondary .cmp-ctaitem__anchor{color:#fff;font-size:14px}.cmp-p-ctaitem.m--btn-secondary .cmp-ctaitem:hover{background-color:#222;border:solid 1px #222}.cmp-p-ctaitem.m--btn-secondary .cmp-ctaitem:active{box-shadow:inset 0 2px 5px 2px #222;background-color:#555759}.cmp-p-ctaitem.m--btn-secondary .cmp-ctaitem__icon{margin-top:8px;margin-left:8px}.cmp-p-ctaitem.m--btn-outline .cmp-ctaitem{display:inline-block;text-align:center;margin:0;border-radius:3px;font-weight:700;font-size:14px;height:40px;padding:0 24px 0 24px;box-sizing:border-box;line-height:40px;color:#222;width:auto;background-color:#fff;border:solid 1px #dcdcdc}.cmp-p-ctaitem.m--btn-outline .cmp-ctaitem__anchor{color:#0071d0;font-size:14px}.cmp-p-ctaitem.m--btn-outline .cmp-ctaitem:hover{background-color:#fff;border:solid 1px #0071d0}.cmp-p-ctaitem.m--btn-outline .cmp-ctaitem:active{box-shadow:inset 0 2px 5px 2px #dcdcdc}.cmp-p-ctaitem.m--btn-outline .cmp-ctaitem__icon{margin-top:8px;margin-left:8px}.cmp-p-ctaitem.m--btn-info .cmp-ctaitem{display:inline-block;text-align:center;margin:0;border-radius:3px;font-weight:700;font-size:14px;height:40px;padding:0 24px 0 24px;box-sizing:border-box;line-height:40px;color:#222;width:auto;color:#555759;background-color:#fff;border:solid 1px #dcdcdc}.cmp-p-ctaitem.m--btn-info .cmp-ctaitem__anchor{color:#555759;font-size:14px}.cmp-p-ctaitem.m--btn-info .cmp-ctaitem:hover{border:solid 1px #555759}.cmp-p-ctaitem.m--btn-info .cmp-ctaitem:active{box-shadow:inset 0 2px 5px 2px #dcdcdc}.cmp-p-ctaitem.m--btn-info .cmp-ctaitem__icon{margin-top:8px;margin-left:8px}.cmp-p-ctaitem.m--btn-white .cmp-ctaitem{display:inline-block;text-align:center;margin:0;border-radius:3px;font-weight:700;font-size:14px;height:40px;padding:0 24px 0 24px;box-sizing:border-box;line-height:40px;color:#222;width:auto;background:0 0;border:solid 1px #fff}.cmp-p-ctaitem.m--btn-white .cmp-ctaitem__anchor{color:#fff;font-size:14px}.cmp-p-ctaitem.m--btn-white .cmp-ctaitem__anchor:hover{color:#222}.cmp-p-ctaitem.m--btn-white .cmp-ctaitem:hover{color:#222;background-color:#fff;border:solid 1px #fff}.cmp-p-ctaitem.m--btn-white .cmp-ctaitem:active{box-shadow:inset 0 2px 5px 2px #dcdcdc}.cmp-p-ctaitem.m--btn-white .cmp-ctaitem__icon{margin-top:8px;margin-left:8px}.cmp-p-ctaitem.m--btn-link .cmp-ctaitem{display:inline-block;text-align:left;margin:0;border-radius:3px;font-weight:700;font-size:14px;height:40px;box-sizing:border-box;line-height:40px;width:auto;border:none;background:0 0;color:#0071d0;padding:0;align-items:center}.cmp-p-ctaitem.m--btn-link .cmp-ctaitem:hover{border:none;color:#005daa}.cmp-p-ctaitem.m--btn-link .cmp-ctaitem:hover .cmp-ctaitem__icon{color:#005daa}.cmp-p-ctaitem.m--btn-link .cmp-ctaitem:active{border:none;background:0 0;color:#262262}.cmp-p-ctaitem.m--btn-link .cmp-ctaitem:active .cmp-ctaitem__icon{color:#262262}.cmp-p-ctaitem.m--btn-link .cmp-ctaitem__anchor{font-size:14px}.cmp-p-ctaitem.m--btn-link .cmp-ctaitem__icon{float:left;display:inline-block;padding-top:8px;margin-right:8px;color:#0071d0}.cmp-p-ctaitem.m--mini .cmp-ctaitem{height:30px;line-height:30px;padding:0 16px 0 16px}.cmp-p-ctaitem.m--mini .cmp-ctaitem__icon{margin-top:2px}.cmp-p-ctaitem.m--small .cmp-ctaitem{height:34px;line-height:34px;padding:0 16px 0 16px}.cmp-p-ctaitem.m--small .cmp-ctaitem__icon{margin-top:5px}.cmp-p-ctaitem.m--large .cmp-ctaitem{height:50px;line-height:50px;padding:0 24px 0 24px}.cmp-p-ctaitem.m--large .cmp-ctaitem__icon{margin-top:12px}.cmp-p-ctaitem.m--block .cmp-ctaitem{width:100%}.cmp-p-ctaitem.m--left-icon .cmp-ctaitem__icon{display:inline-block;float:left;width:24px;margin-right:10px;margin-left:0}.cmp-p-ctaitem.m--lc-cta .cmp-ctaitem{width:fit-content}.cmp-p-ctaitem.m--lc-cta .cmp-ctaitem__icon{left:0;float:right;margin-right:10px;margin-left:10px}.cmp-p-ctaitem.m--lc-cta-left{margin-top:24px}.cmp-p-ctaitem.m--lc-cta-left .cmp-ctaitem__icon{float:left;margin-right:10px;margin-left:10px;transform:rotate(179deg)}@media (min-width:1200px){.cmp-p-ctaitem.m--sticky-lc{position:fixed;top:155px;max-width:245px}}.m-l1{margin:16px}.m-l2{margin:24px}.m-l3{margin:32px}.m-l4{margin:48px}.m-l5{margin:64px}.m-l0{margin:0!important}.mx-l1{margin:0 16px}.mx-l2{margin:0 24px}.mx-l3{margin:0 32px}.mx-l4{margin:0 48px}.mx-l5{margin:0 64px}.mx-l1{margin:16px 0}.mx-l2{margin:24px 0}.mx-l3{margin:32px 0}.mx-l4{margin:48px 0}.mx-l5{margin:64px 0}.mt-l1{margin-top:16px}.mt-l2{margin-top:24px}.mt-l3{margin-top:32px}.mt-l4{margin-top:48px}.mt-l5{margin-top:64px}.mb-l1{margin-bottom:16px}.mb-l2{margin-bottom:24px}.mb-l3{margin-bottom:32px}.mb-l4{margin-bottom:48px}.mb-l5{margin-bottom:64px}.ml-l1{margin-left:16px}.ml-l2{margin-left:24px}.ml-l3{margin-left:32px}.ml-l4{margin-left:48px}.ml-l5{margin-left:64px}.mr-l1{margin-right:16px}.mr-l2{margin-right:24px}.mr-l3{margin-right:32px}.mr-l4{margin-right:48px}.mr-l5{margin-right:64px}.p-l1{padding:16px}.p-l2{padding:24px}.p-l3{padding:32px}.p-l4{padding:48px}.p-l5{padding:64px}.p-l0{padding:0!important}.px-l1{padding:0 16px}.px-l2{padding:0 24px}.px-l3{padding:0 32px}.px-l4{padding:0 48px}.px-l5{padding:0 64px}.px-l1{padding:16px 0}.px-l2{padding:24px 0}.px-l3{padding:32px 0}.px-l4{padding:48px 0}.px-l5{padding:64px 0}.pt-l1{padding-top:16px}.pt-l2{padding-top:24px}.pt-l3{padding-top:32px}.pt-l4{padding-top:48px}.pt-l5{padding-top:64px}.pb-l1{padding-bottom:16px}.pb-l2{padding-bottom:24px}.pb-l3{padding-bottom:32px}.pb-l4{padding-bottom:48px}.pb-l5{padding-bottom:64px}.pl-l1{padding-left:16px}.pl-l2{padding-left:24px}.pl-l3{padding-left:32px}.pl-l4{padding-left:48px}.pl-l5{padding-left:64px}.pr-l1{padding-right:16px}.pr-l2{padding-right:24px}.pr-l3{padding-right:32px}.pr-l4{padding-right:48px}.pr-l5{padding-right:64px}.mt-s0{margin-top:0}.mt-s1{margin-top:2px}.mt-s2{margin-top:4px}.mt-s3{margin-top:8px}.mt-s4{margin-top:12px}.mt-s5{margin-top:16px}.mt-s6{margin-top:24px}.mt-s7{margin-top:32px}.mt-s8{margin-top:40px}.mt-s9{margin-top:48px}.mb-s0{margin-bottom:0}.mb-s1{margin-bottom:2px}.mb-s2{margin-bottom:4px}.mb-s3{margin-bottom:8px}.mb-s4{margin-bottom:12px}.mb-s5{margin-bottom:16px}.mb-s6{margin-bottom:24px}.mb-s7{margin-bottom:32px}.mb-s8{margin-bottom:40px}.mb-s9{margin-bottom:48px}.ml-s0{margin-left:0}.ml-s1{margin-left:2px}.ml-s2{margin-left:4px}.ml-s3{margin-left:8px}.ml-s4{margin-left:12px}.ml-s5{margin-left:16px}.ml-s6{margin-left:24px}.ml-s7{margin-left:32px}.ml-s8{margin-left:40px}.ml-s9{margin-left:48px}.mr-s0{margin-right:0}.mr-s1{margin-right:2px}.mr-s2{margin-right:4px}.mr-s3{margin-right:8px}.mr-s4{margin-right:12px}.mr-s5{margin-right:16px}.mr-s6{margin-right:24px}.mr-s7{margin-right:32px}.mr-s8{margin-right:40px}.mr-s9{margin-right:48px}.pt-s0{padding-top:0}.pt-s1{padding-top:2px}.pt-s2{padding-top:4px}.pt-s3{padding-top:8px}.pt-s4{padding-top:12px}.pt-s5{padding-top:16px}.pt-s6{padding-top:24px}.pt-s7{padding-top:32px}.pt-s8{padding-top:40px}.pt-s9{padding-top:48px}.pb-s0{padding-bottom:0}.pb-s1{padding-bottom:2px}.pb-s2{padding-bottom:4px}.pb-s3{padding-bottom:8px}.pb-s4{padding-bottom:12px}.pb-s5{padding-bottom:16px}.pb-s6{padding-bottom:24px}.pb-s7{padding-bottom:32px}.pb-s8{padding-bottom:40px}.pb-s9{padding-bottom:48px}.pl-s0{padding-left:0}.pl-s1{padding-left:2px}.pl-s2{padding-left:4px}.pl-s3{padding-left:8px}.pl-s4{padding-left:12px}.pl-s5{padding-left:16px}.pl-s6{padding-left:24px}.pl-s7{padding-left:32px}.pl-s8{padding-left:40px}.pl-s9{padding-left:48px}.pr-s0{padding-right:0}.pr-s1{padding-right:2px}.pr-s2{padding-right:4px}.pr-s3{padding-right:8px}.pr-s4{padding-right:12px}.pr-s5{padding-right:16px}.pr-s6{padding-right:24px}.pr-s7{padding-right:32px}.pr-s8{padding-right:40px}.pr-s9{padding-right:48px}.search{position:relative;padding:0;background:#f3f3f3}.search button,.search input{font-size:14px;margin-bottom:0;box-shadow:none}.search input{text-transform:none;letter-spacing:1px;background:0 0;border:1px solid #f3f3f3;padding:0 8px;width:190px;height:28px;line-height:28px;margin:0;outline:0;color:#333;position:relative;z-index:1;color:#333}.search input.selector-input-adjust{width:190px}.search input.suggested{color:#c9c8c8}.search input::-ms-clear{display:none;width:0;height:0}.search .search-button{background:0 0;border:none;float:right;height:30px;margin:0;text-align:center;padding:0;width:40px;filter:none;outline:0!important;border-bottom:4px solid transparent}.search .search-button span{display:inline-block;vertical-align:middle;background:url(../images/white/icons-utility.png);width:22px;height:26px;background-position:-4px -267px;text-indent:-9999px}.search .search-button.active{border-color:#ee3134}.search form.active input{width:330px}.search form.active input.selector-input-adjust{width:190px}.search form .searchAutoCompleteProviderSelector{position:relative;top:1px;width:160px;height:28px;background-color:#c9c8c8;border-radius:0;border:0;outline:1px solid #d8d8d8;margin:0;float:left}.search form .searchAutoCompleteProviderSelector:focus optgroup,.search form .searchAutoCompleteProviderSelector:focus option{background-color:#fff}.search form .searchAutoCompleteProviderSelector optgroup,.search form .searchAutoCompleteProviderSelector option{background-color:#e5e5e5}.search form.providers-enabled input{width:190px}.search li,.search ul{margin:0}.clearable{display:inline-block;position:absolute;cursor:pointer;right:.85rem;top:.85rem;font-size:1.2rem;z-index:54;width:18px;height:28px}.searchRemoveHide{display:none!important}div.search{padding:0}#search-mobile-button{display:none;position:fixed;left:35px;margin-top:-32px}#header-typeahead-suggested{display:none;color:#aaa;-webkit-text-fill-color:#aaa;position:absolute;top:0;right:1px;left:0;bottom:1px;background:0 0;z-index:0;width:100%}#header-typeahead-suggested.active{display:block}.ac_results{box-shadow:0 1px 2px rgba(0,0,0,.1);background:#fff;border:1px solid #d8d8d8;padding:10px;z-index:1;right:50px!important;top:34px!important}.ac_results li{color:#555;cursor:pointer;padding:2px 5px}.ac_results li.ac_over,.ac_results li:hover{background:#f8f8f8;color:#007ed5;cursor:pointer;text-decoration:none}.ac_results li.ac_skip,.ac_results li.ac_skip:hover{background:#fff;border-bottom:1px solid #d8d8d8;color:#1a2155;cursor:text;display:block;font-weight:700;padding:0 5px 5px 5px;margin-bottom:5px;text-decoration:none}.ac_results li.ac_skip em{font-style:normal}#header-typeahead{left:2px;z-index:500;overflow:hidden;width:663px;background:#fff;position:absolute;box-shadow:0 2px 2px rgba(0,0,0,.1);display:none;margin-top:2px;margin-left:-2px;outline:0}#header-typeahead a{cursor:pointer}#header-typeahead .typeahead-terms{float:left;width:70%;position:relative;z-index:508;overflow:hidden;font-size:12px}#header-typeahead .typeahead-group{background:#f7f7f7;border-radius:2px;padding:5px 20px!important}#header-typeahead .typeahead-span strong{font-weight:400;color:gray}#header-typeahead .typeahead-flyout{float:left;width:442px;height:300px;background:#f8f8f8;border-left:1px solid #d8d8d8;padding:10px;position:relative;left:-1px;z-index:501;overflow:hidden}#header-typeahead ul{list-style:none}#header-typeahead .typeahead-term-list li{display:block;line-height:22px;padding:5px 10px;width:100%!important}#header-typeahead .typeahead-term-list li.typeahead-ignore{padding:0;margin:0}#header-typeahead .typeahead-term-list li a{display:block;width:100%!important}#header-typeahead .typeahead-term-list li a.typeahead-term{display:inline-block;color:#333;text-overflow:ellipsis;overflow:hidden;white-space:nowrap;vertical-align:middle;border-bottom:2px solid transparent}#header-typeahead .typeahead-term-list li.highlighted{background:#ebf2fa!important}#header-typeahead span.typeahead-hr{display:block;border-bottom:1px solid #d8d8d8;margin-top:10px;margin-bottom:10px}#header-typeahead .typeahead-term-list a.typeahead-term.active span{border-bottom:0}#header-typeahead .typeahead-term-list a.typeahead-term.active span .title-text{border-bottom:0}#header-typeahead .title-text{color:#1e8ae7}#header-typeahead .search-suggestions{padding:10px;margin-bottom:5px;font-weight:700;cursor:default;background-color:#e5e5e5}.flyout-recent-searches,.flyout-typeahead{display:none}.flyout-recent-searches li{display:block;line-height:22px;padding:0 10px}.flyout-recent-searches li.term a{display:inline-block;color:#333;text-overflow:ellipsis;overflow:hidden;white-space:nowrap;border-bottom:2px solid transparent;width:100%!important}.flyout-recent-searches li.term a.active span{border-bottom:2px solid #ee3134}.flyout-recent-searches li.term a:hover{background-color:#ebf2fa}.flyout-recent-searches li.recent-searches{padding:10px;margin-bottom:5px;font-weight:700;cursor:default;background-color:#f9f9f9;font-weight:700}.flyout-recent-searches li.recent-searches em{font-style:normal}.flyout-search-shortcut .search-shortcut-list{border-top:1px solid #d8d8d8}.flyout-search-shortcut .search-shortcut-list li{display:block;line-height:22px;padding:0 10px}.flyout-search-shortcut .search-shortcut-list li.quickLinks a{display:inline-block;color:#1e8ae7;text-overflow:ellipsis;overflow:hidden;white-space:nowrap;border-bottom:2px solid transparent;width:100%!important}.flyout-search-shortcut_right{width:30%;float:right}.searchAutoCompleteProviderSelectorIE78{padding-top:4px;padding-bottom:3px;width:180px;height:30px;position:absolute;left:4px;top:4px;border:1px solid #d8d8d8;background-color:#e5e5e5;z-index:2}.searchAutoCompleteProviderSelectorIE78:focus{width:auto;background-color:#fff}.msie78Search{width:190px}.ie8 .header_row_1.layout_cont_middle{clear:both!important}.ie8 .header_row_2.layout_cont_middle{margin-left:285px!important}.ie8 #meganav-content{display:block!important}.ie8 .hide-meganav #meganav-content{display:none!important}@media (max-width:979px){.typeahead-group{padding:5px 30px!important}.general_search.layout_cont_middle{margin-right:0}.header_row_2.layout_cont_left{width:95%;float:none;margin:auto}.header_row_2.layout_cont_middle{width:95%;margin:auto}.header_row_2.layout_cont_left,.header_row_2.layout_cont_middle{padding:0 15px 0 15px!important}.layout_cont_right{float:none;width:100%}#mobile-search-button-container{float:right;width:50px;height:60px;border-left:1px solid #eee;border-right:1px solid #eee}#search-mobile-button{display:block;height:60px;width:50px;border:none;background:0 0;background-image:url(/etc/designs/lifetech/clientlibs/base/img/icon-search-black.svg);background-repeat:no-repeat;background-position:center;position:relative;left:0;margin-top:0}#search-mobile-button.active{border-bottom:3px solid #ee3134;background-image:url(/etc/designs/lifetech/clientlibs/base/img/icon-cross-black.svg);background-repeat:no-repeat;background-size:18px 18px}#focusAreaSelector{width:100%!important;margin:auto}.container-modifier{padding:0!important}#search-main.in{display:block;overflow:auto;overflow-x:hidden;overflow-y:auto;position:fixed;z-index:200;bottom:0;top:61px;left:0;right:0;background:#fff}#search-main.in .searchHeading{display:block!important;padding:40px 0 24px 0;font-size:25.35px;color:#a2a2a2;text-align:center;font-weight:400}#search-main.in .searchHeading span{color:#333;font-weight:700}.global-commerce-bar .logo img{height:28px}.search form{background:#fff;height:auto;border:none!important;margin-top:0;margin:auto;width:100%}.search form input{box-sizing:border-box;line-height:40px;height:60px;width:100%!important;-webkit-appearance:none;-moz-appearance:none;appearance:none;border:1px solid #dcdcdc}.search form input.active input{height:60px!important}.search form input.selector-input-adjust{width:100%}.search form .search-button{display:none;position:absolute;top:273px;width:100%!important;height:46px;padding-top:0;color:#fff;line-height:46px;border-radius:3px 3px!important;margin:auto;left:0;right:0}.search form .search-button img{display:none}.search form .search-button .search-text{display:inline-block}.search form .searchAutoCompleteProviderSelector{top:0;width:100%!important;line-height:40px;height:40px;float:none}#header-typeahead-input-container{width:100%;height:60px;left:0;right:0;margin:auto;padding:16px 0 16px 0;background:#fff}#header-typeahead{width:100%;top:77px;margin:auto;left:0;right:0}}@media only screen and (max-device-width:320px){.global-commerce-bar{height:60px;position:fixed;top:0;left:0;width:100%;margin:0;background:#fff;z-index:80;font-size:14px;border-bottom:1px solid #eee}.global-commerce-bar .logo{margin:0 0 0 54px!important;text-align:left;padding:15px 0 15px 0}.global-commerce-bar .user-utility{padding:0;margin:0}#header-nav-container #header-nav-button{width:50px;padding-left:15px}.search form{height:60px}.search form .search-button{display:block;position:absolute;top:229px;height:46px;padding-top:0;color:#fff;line-height:46px;border-radius:4px;margin:auto}.search form .search-button img{display:none}.search form .search-button .search-text{display:inline-block}.search form .searchAutoCompleteProviderSelector{height:60px}#mobile-search-button-container,#search-mobile-button{width:40px}#search-main.in{min-height:568px}#search-main.in .searchHeading{padding:16px 0 13px 0}#search-main.in .searchHeading p{font-size:16.25px}}@media (max-width:767px){.search-button{display:none}.clearable{top:2.25rem;right:2.85rem}.typeahead-group{padding:5px 10px!important}}@media (max-width:979px){.search form.active input{height:60px!important}.clearable{top:2.25rem!important;right:2.85rem!important}}.search{padding:0;background:0 0}.search .largeSearchBar .loading-wheel-sm{margin:16px 16px}.search button,.search input{font-size:14px;margin-bottom:0;box-shadow:none}.search input{height:50px;width:100%;box-sizing:border-box;background:0 0;letter-spacing:0;font-size:13px;padding-left:22px;border:none;border-top:1px solid #d8d8d8;border-bottom:1px solid #d8d8d8;line-height:28px;margin:0;outline:0;position:relative;z-index:1;color:#000}.search input.selector-input-adjust{width:100%}.search input::-ms-clear{display:none}.search input:-moz-placeholder,.search input:-ms-input-placeholder,.search input::-moz-placeholder,.search input::-webkit-input-placeholder,.search input::placeholder{color:#a2a2a2}.search .search-button span{display:inline-block;vertical-align:middle}.search .search-button.active{border-color:#ee3134}.search form{margin:0}.search form .search-button{border-radius:0 3px 3px 0!important;margin:0;text-align:center;filter:none;outline:0!important;border:none;height:50px;width:100px;background:#4a4a4a}.search form .search-button .search-text{display:none}.search form.active input{height:100%}.search form.active input.selector-input-adjust{width:100%}.search form .searchAutoCompleteProviderSelector{position:relative;width:285px;height:50px;background-color:#f9f9f9;border:0;margin:0;line-height:normal}.search form .searchAutoCompleteProviderSelector:focus optgroup,.search form .searchAutoCompleteProviderSelector:focus option{background-color:#fff}.search form .searchAutoCompleteProviderSelector optgroup,.search form .searchAutoCompleteProviderSelector option{background-color:#e5e5e5}.search li,.search ul{margin:0}.clearable{background:transparent url(/search/searchbar/resources/images/icon_16_close_mono@1_5x.svg) no-repeat right -20px center}.clearable.x{background-position:right 20px center}.clearable.onX{cursor:pointer}.clearable::-ms-clear{display:none;width:0;height:0}div.search{padding:0}#header-typeahead-input-container{width:100%;height:50px}#header-typeahead{width:100%;z-index:500;background:#fff;position:absolute;box-shadow:0 2px 2px rgba(0,0,0,.1);display:none;margin-top:0;outline:0}#header-typeahead a{cursor:pointer}#header-typeahead .typeahead-terms{float:left;width:70%;position:relative;z-index:508;overflow-y:auto;overflow-x:hidden;max-height:510px;font-size:12px}#header-typeahead .typeahead-term-list li a.typeahead-term{font-weight:500}.searchAutoCompleteProviderSelectorIE78{width:203px;height:52px;background-color:#f9f9f9;border:solid 0 #cdcccc;position:relative;top:0;outline:1px solid #d8d8d8;margin:0;float:left;padding-top:4px;line-height:normal;z-index:2}.searchAutoCompleteProviderSelectorIE78:focus{width:auto;background-color:#fff}.search-btn-icon{width:28px;height:28px}.chosen-container{position:relative;display:inline-block;vertical-align:middle;font-size:14px;-webkit-user-select:none;-moz-user-select:none;-ms-user-select:none;user-select:none}.chosen-container *{-webkit-box-sizing:border-box;box-sizing:border-box}.chosen-container .chosen-drop{position:absolute;top:100%;z-index:1010;width:100%;border:1px solid #aaa;border-top:0;background:#fff;-webkit-box-shadow:0 4px 5px rgba(0,0,0,.15);box-shadow:0 4px 5px rgba(0,0,0,.15);clip:rect(0,0,0,0);-webkit-clip-path:inset(100% 100%);clip-path:inset(100% 100%)}.chosen-container a{cursor:pointer}.chosen-container .chosen-single .group-name{margin-right:4px;overflow:hidden;white-space:nowrap;text-overflow:ellipsis;font-weight:400;color:#999}.chosen-container .chosen-single .group-name:after{content:":";padding-left:2px;vertical-align:top}.chosen-container .search-choice .group-name{margin-right:4px;overflow:hidden;white-space:nowrap;text-overflow:ellipsis;font-weight:400;color:#999}.chosen-container .search-choice .group-name:after{content:":";padding-left:2px;vertical-align:top}.chosen-container .chosen-results{color:#444;position:relative;overflow-x:hidden;overflow-y:auto;margin:0 4px 4px 0;padding:0 0 0 4px;max-height:350px;-webkit-overflow-scrolling:touch}.chosen-container .chosen-results li{display:none;margin:0;padding:5px 6px;list-style:none;line-height:15px;word-wrap:break-word;-webkit-touch-callout:none}.chosen-container .chosen-results li em{font-style:normal;text-decoration:underline}.chosen-container .chosen-results li.active-result{display:list-item;cursor:pointer}.chosen-container .chosen-results li.disabled-result{display:list-item;color:#ccc;cursor:default}.chosen-container .chosen-results li.highlighted{background-color:#3875d7;background-image:-webkit-gradient(linear,left top,left bottom,color-stop(20%,#3875d7),color-stop(90%,#2a62bc));background-image:linear-gradient(#3875d7 20%,#2a62bc 90%);color:#fff}.chosen-container .chosen-results li.no-results{color:#777;display:list-item;background:#f4f4f4}.chosen-container .chosen-results li.group-result{display:list-item;font-weight:700;cursor:default}.chosen-container .chosen-results li.group-option{padding-left:15px}.chosen-container.chosen-with-drop .chosen-drop{clip:auto;-webkit-clip-path:none;clip-path:none}.chosen-container-single .chosen-single{position:relative;display:block;overflow:hidden;padding:0 0 0 8px;height:25px;border:1px solid #aaa;border-radius:5px;background-color:#fff;background:-webkit-gradient(linear,left top,left bottom,color-stop(20%,#fff),color-stop(50%,#f6f6f6),color-stop(52%,#eee),to(#f4f4f4));background:linear-gradient(#fff 20%,#f6f6f6 50%,#eee 52%,#f4f4f4 100%);background-clip:padding-box;-webkit-box-shadow:0 0 3px #fff inset,0 1px 1px rgba(0,0,0,.1);box-shadow:0 0 3px #fff inset,0 1px 1px rgba(0,0,0,.1);color:#444;text-decoration:none;white-space:nowrap;line-height:24px}.chosen-container-single .chosen-single span{display:block;overflow:hidden;margin-right:26px;text-overflow:ellipsis;white-space:nowrap}.chosen-container-single .chosen-single abbr{position:absolute;top:6px;right:26px;display:block;width:12px;height:12px;background:url(/search/searchbar/resources/images/chosen-sprite.png) -42px 1px no-repeat;font-size:1px}.chosen-container-single .chosen-single abbr:hover{background-position:-42px -10px}.chosen-container-single .chosen-single div{position:absolute;top:0;right:0;display:block;width:18px;height:100%}.chosen-container-single .chosen-single div b{display:block;width:100%;height:100%;background:url(/search/searchbar/resources/images/chosen-sprite.png) no-repeat 0 2px}.chosen-container-single .chosen-default{color:#999}.chosen-container-single .chosen-single-with-deselect span{margin-right:38px}.chosen-container-single .chosen-search{position:relative;z-index:1010;margin:0;padding:3px 4px;white-space:nowrap}.chosen-container-single .chosen-search input[type=text]{margin:1px 0;padding:4px 20px 4px 5px;width:100%;height:auto;outline:0;border:1px solid #aaa;background:url(/search/searchbar/resources/images/chosen-sprite.png) no-repeat 100% -20px;font-size:1em;font-family:sans-serif;line-height:normal;border-radius:0}.chosen-container-single .chosen-drop{margin-top:-1px;border-radius:0 0 4px 4px;background-clip:padding-box}.chosen-container-single.chosen-disabled .chosen-single abbr:hover{background-position:-42px -10px}.chosen-container-single.chosen-container-single-nosearch .chosen-search{position:absolute;clip:rect(0,0,0,0);-webkit-clip-path:inset(100% 100%);clip-path:inset(100% 100%)}.chosen-container-multi .chosen-choices{position:relative;overflow:hidden;margin:0;padding:0 5px;width:100%;height:auto;border:1px solid #aaa;background-color:#fff;background-image:-webkit-gradient(linear,left top,left bottom,color-stop(1%,#eee),color-stop(15%,#fff));background-image:linear-gradient(#eee 1%,#fff 15%);cursor:text}.chosen-container-multi .chosen-choices li{float:left;list-style:none}.chosen-container-multi .chosen-choices li.search-field{margin:0;padding:0;white-space:nowrap}.chosen-container-multi .chosen-choices li.search-field input[type=text]{margin:1px 0;padding:0;height:25px;outline:0;border:0!important;background:0 0!important;-webkit-box-shadow:none;box-shadow:none;color:#999;font-size:100%;font-family:sans-serif;line-height:normal;border-radius:0;width:25px}.chosen-container-multi .chosen-choices li.search-choice{position:relative;margin:3px 5px 3px 0;padding:3px 20px 3px 5px;border:1px solid #aaa;max-width:100%;border-radius:3px;background-color:#eee;background-image:-webkit-gradient(linear,left top,left bottom,color-stop(20%,#f4f4f4),color-stop(50%,#f0f0f0),color-stop(52%,#e8e8e8),to(#eee));background-image:linear-gradient(#f4f4f4 20%,#f0f0f0 50%,#e8e8e8 52%,#eee 100%);background-size:100% 19px;background-repeat:repeat-x;background-clip:padding-box;-webkit-box-shadow:0 0 2px #fff inset,0 1px 0 rgba(0,0,0,.05);box-shadow:0 0 2px #fff inset,0 1px 0 rgba(0,0,0,.05);color:#333;line-height:13px;cursor:default}.chosen-container-multi .chosen-choices li.search-choice span{word-wrap:break-word}.chosen-container-multi .chosen-choices li.search-choice .search-choice-close{position:absolute;top:4px;right:3px;display:block;width:12px;height:12px;background:url(/search/searchbar/resources/images/chosen-sprite.png) -42px 1px no-repeat;font-size:1px}.chosen-container-multi .chosen-choices li.search-choice .search-choice-close:hover{background-position:-42px -10px}.chosen-container-multi .chosen-choices li.search-choice-disabled{padding-right:5px;border:1px solid #ccc;background-color:#e4e4e4;background-image:-webkit-gradient(linear,left top,left bottom,color-stop(20%,#f4f4f4),color-stop(50%,#f0f0f0),color-stop(52%,#e8e8e8),to(#eee));background-image:linear-gradient(#f4f4f4 20%,#f0f0f0 50%,#e8e8e8 52%,#eee 100%);color:#666}.chosen-container-multi .chosen-choices li.search-choice-focus{background:#d4d4d4}.chosen-container-multi .chosen-choices li.search-choice-focus .search-choice-close{background-position:-42px -10px}.chosen-container-multi .chosen-results{margin:0;padding:0}.chosen-container-multi .chosen-drop .result-selected{display:list-item;color:#ccc;cursor:default}.chosen-container-active .chosen-single{border:1px solid #5897fb;-webkit-box-shadow:0 0 5px rgba(0,0,0,.3);box-shadow:0 0 5px rgba(0,0,0,.3)}.chosen-container-active .chosen-choices{border:1px solid #5897fb;-webkit-box-shadow:0 0 5px rgba(0,0,0,.3);box-shadow:0 0 5px rgba(0,0,0,.3)}.chosen-container-active .chosen-choices li.search-field input[type=text]{color:#222!important}.chosen-container-active.chosen-with-drop .chosen-single{border:1px solid #aaa;border-bottom-right-radius:0;border-bottom-left-radius:0;background-image:-webkit-gradient(linear,left top,left bottom,color-stop(20%,#eee),color-stop(80%,#fff));background-image:linear-gradient(#eee 20%,#fff 80%);-webkit-box-shadow:0 1px 0 #fff inset;box-shadow:0 1px 0 #fff inset}.chosen-container-active.chosen-with-drop .chosen-single div{border-left:none;background:0 0}.chosen-container-active.chosen-with-drop .chosen-single div b{background-position:-18px 2px}.chosen-disabled{opacity:.5!important;cursor:default}.chosen-disabled .chosen-single{cursor:default}.chosen-disabled .chosen-choices .search-choice .search-choice-close{cursor:default}.chosen-rtl{text-align:right}.chosen-rtl .chosen-single{overflow:visible;padding:0 8px 0 0}.chosen-rtl .chosen-single span{margin-right:0;margin-left:26px;direction:rtl}.chosen-rtl .chosen-single div{right:auto;left:3px}.chosen-rtl .chosen-single abbr{right:auto;left:26px}.chosen-rtl .chosen-single-with-deselect span{margin-left:38px}.chosen-rtl .chosen-choices li{float:right}.chosen-rtl .chosen-choices li.search-field input[type=text]{direction:rtl}.chosen-rtl .chosen-choices li.search-choice{margin:3px 5px 3px 0;padding:3px 5px 3px 19px}.chosen-rtl .chosen-choices li.search-choice .search-choice-close{right:auto;left:4px}.chosen-rtl .chosen-results li.group-option{padding-right:15px;padding-left:0}.chosen-rtl .chosen-search input[type=text]{padding:4px 5px 4px 20px;background:url(/search/searchbar/resources/resources/images/chosen-sprite.png) no-repeat -30px -20px;direction:rtl}.chosen-rtl.chosen-container-single .chosen-results{margin:0 0 4px 4px;padding:0 4px 0 0}.chosen-rtl.chosen-container-single .chosen-single div b{background-position:6px 2px}.chosen-rtl.chosen-container-active.chosen-with-drop .chosen-single div{border-right:none}.chosen-rtl.chosen-container-single.chosen-with-drop .chosen-single div b{background-position:-12px 2px}@media only screen and (-webkit-min-device-pixel-ratio:1.5){.chosen-container .chosen-results-scroll-down span{background-image:url(/search/searchbar/resources/images/chosen-sprite@2x.png)!important;background-size:52px 37px!important;background-repeat:no-repeat!important}.chosen-container .chosen-results-scroll-up span{background-image:url(/search/searchbar/resources/images/chosen-sprite@2x.png)!important;background-size:52px 37px!important;background-repeat:no-repeat!important}.chosen-container-multi .chosen-choices .search-choice .search-choice-close{background-image:url(/search/searchbar/resources/images/chosen-sprite@2x.png)!important;background-size:52px 37px!important;background-repeat:no-repeat!important}.chosen-container-single .chosen-search input[type=text]{background-image:url(/search/searchbar/resources/images/chosen-sprite@2x.png)!important;background-size:52px 37px!important;background-repeat:no-repeat!important}.chosen-container-single .chosen-single abbr{background-image:url(/search/searchbar/resources/images/chosen-sprite@2x.png)!important;background-size:52px 37px!important;background-repeat:no-repeat!important}.chosen-container-single .chosen-single div b{background-image:url(/search/searchbar/resources/images/chosen-sprite@2x.png)!important;background-size:52px 37px!important;background-repeat:no-repeat!important}.chosen-rtl .chosen-search input[type=text]{background-image:url(/search/searchbar/resources/images/chosen-sprite@2x.png)!important;background-size:52px 37px!important;background-repeat:no-repeat!important}}@media only screen and (min-resolution:144dpi){.chosen-container .chosen-results-scroll-down span{background-image:url(/search/searchbar/resources/images/chosen-sprite@2x.png)!important;background-size:52px 37px!important;background-repeat:no-repeat!important}.chosen-container .chosen-results-scroll-up span{background-image:url(/search/searchbar/resources/images/chosen-sprite@2x.png)!important;background-size:52px 37px!important;background-repeat:no-repeat!important}.chosen-container-multi .chosen-choices .search-choice .search-choice-close{background-image:url(/search/searchbar/resources/images/chosen-sprite@2x.png)!important;background-size:52px 37px!important;background-repeat:no-repeat!important}.chosen-container-single .chosen-search input[type=text]{background-image:url(/search/searchbar/resources/images/chosen-sprite@2x.png)!important;background-size:52px 37px!important;background-repeat:no-repeat!important}.chosen-container-single .chosen-single abbr{background-image:url(/search/searchbar/resources/images/chosen-sprite@2x.png)!important;background-size:52px 37px!important;background-repeat:no-repeat!important}.chosen-container-single .chosen-single div b{background-image:url(/search/searchbar/resources/images/chosen-sprite@2x.png)!important;background-size:52px 37px!important;background-repeat:no-repeat!important}.chosen-rtl .chosen-search input[type=text]{background-image:url(/search/searchbar/resources/images/chosen-sprite@2x.png)!important;background-size:52px 37px!important;background-repeat:no-repeat!important}}@media only screen and (min-resolution:1.5dppx){.chosen-container .chosen-results-scroll-down span{background-image:url(/search/searchbar/resources/images/chosen-sprite@2x.png)!important;background-size:52px 37px!important;background-repeat:no-repeat!important}.chosen-container .chosen-results-scroll-up span{background-image:url(/search/searchbar/resources/images/chosen-sprite@2x.png)!important;background-size:52px 37px!important;background-repeat:no-repeat!important}.chosen-container-multi .chosen-choices .search-choice .search-choice-close{background-image:url(/search/searchbar/resources/images/chosen-sprite@2x.png)!important;background-size:52px 37px!important;background-repeat:no-repeat!important}.chosen-container-single .chosen-search input[type=text]{background-image:url(/search/searchbar/resources/images/chosen-sprite@2x.png)!important;background-size:52px 37px!important;background-repeat:no-repeat!important}.chosen-container-single .chosen-single abbr{background-image:url(/search/searchbar/resources/images/chosen-sprite@2x.png)!important;background-size:52px 37px!important;background-repeat:no-repeat!important}.chosen-container-single .chosen-single div b{background-image:url(/search/searchbar/resources/images/chosen-sprite@2x.png)!important;background-size:52px 37px!important;background-repeat:no-repeat!important}.chosen-rtl .chosen-search input[type=text]{background-image:url(/search/searchbar/resources/images/chosen-sprite@2x.png)!important;background-size:52px 37px!important;background-repeat:no-repeat!important}}.chosen-container-single .chosen-single{height:50px!important;border-radius:0!important;border-radius:3px 0 0 3px!important;background-color:#f9f9f9!important;border:1px solid #d8d8d8!important;outline:0!important;background-image:none!important;padding:0 20px 0 16px;box-shadow:none!important}.chosen-container-single .chosen-single>span{line-height:50px}.chosen-container-single .chosen-single div{right:20px}.chosen-container-single .chosen-single div b{background:0 0!important;border-color:#222 transparent transparent transparent;border-style:solid;border-width:5px 4px 0 4px;height:0!important;left:50%;margin-left:-4px;margin-top:-2px;position:absolute;top:50%;width:0!important}.chosen-drop{border-top:1px solid #d8d8d8}.chosen-drop .chosen-results{margin:0!important;padding:0!important;border-top:1px solid #dcdcdc}.chosen-drop .chosen-results .active-result.result-selected,.chosen-drop .chosen-results .active-result.result-selected.highlighted{background-repeat:no-repeat;background-size:10% 100%;background-position:left;color:#fff!important;background-color:#007fff!important;background-image:none!important}.chosen-drop .chosen-results .group-result{border-top:1px solid #dcdcdc;color:#a2a2a2}.chosen-drop .chosen-results li.group-option{padding-left:1.5rem;color:#000;padding-top:5px;padding-bottom:5px;font-size:13px}.chosen-drop .chosen-results li.group-option.highlighted{color:#000!important;background:#ebf2fa!important}.chosen-drop .chosen-results .active-result.highlighted{color:#000!important;background:#ebf2fa!important}@media screen and (max-width:767px){.flyout-typeahead .typeahead-terms{width:100%}.flyout-typeahead .flyout-search-shortcut_right{width:100%;display:flex}.flyout-typeahead .flyout-search-shortcut_right ul{width:100%}.flyout-typeahead .flyout-search-shortcut_right ul .search-suggestions{font-size:100%;font-weight:500!important}}@media (min-width:768px) and (max-width:991px){#header-typeahead{height:calc(100vh - 412px)!important}.flyout-typeahead .typeahead-terms{width:70%!important;float:left!important;border-right:1px solid #e5e5e5}.flyout-typeahead .flyout-search-shortcut_right{width:30%;float:right;border-left:1px solid #e5e5e5}.flyout-typeahead .flyout-search-shortcut_right ul .search-suggestions{font-size:100%;font-weight:500!important}.flyout-typeahead .typeahead-terms .typeahead-term-list{border-bottom:unset!important}}@media (min-width:992px) and (max-width:1023px){.flyout-typeahead .typeahead-terms{width:100%}.flyout-typeahead .flyout-search-shortcut_right{width:100%;display:flex}.flyout-typeahead .flyout-search-shortcut_right ul{width:100%}#header-typeahead .search-shortcut-list{border:unset!important}.flyout-typeahead .flyout-search-shortcut_right ul .search-suggestions{font-size:100%;font-weight:500!important}}@media (min-width:1024px) and (max-width:2560px){.flyout-typeahead .typeahead-terms{width:70%!important;float:left!important;border-right:1px solid #e5e5e5}.flyout-typeahead .flyout-search-shortcut_right{width:30%;float:right;border-left:1px solid #e5e5e5}.flyout-typeahead .flyout-search-shortcut_right ul .search-suggestions{font-size:100%;font-weight:500!important}.flyout-typeahead .typeahead-terms .typeahead-term-list{border-bottom:unset!important}}.layout_cont_middle #autoComplete_list_1{padding-inline-start:0}.layout_cont_middle #autoComplete_list_1 li{list-style:none;cursor:default}.layout_cont_middle .typeahead-term-list-ul{width:100%;z-index:500;background:#fff;position:absolute;box-shadow:0 2px 2px rgba(0,0,0,.1);margin-top:0;outline:0;font-size:12px}.layout_cont_middle .typeahead-term-list-ul .typeahead-list-space{line-height:22px;padding:5px 20px!important;width:70%}.layout_cont_middle .typeahead-term-list-ul .typeahead-list-space:hover{background:#ebf2fa!important}.layout_cont_middle .typeahead-term-list-ul a.typeahead-term{display:inline-block;color:#333!important;text-overflow:ellipsis;overflow:hidden;white-space:nowrap;vertical-align:middle;border-bottom:2px solid transparent;font-weight:500;text-decoration:none!important;width:100%!important;cursor:pointer}.layout_cont_middle .typeahead-term-list-ul a.typeahead-term .typeahead-span mark{font-weight:400;color:gray;background-color:unset}.layout_cont_middle .typeahead-term-list-ul .product-title{font-family:HelveticaNeue,Helvetica,Arial,sans-serif;line-height:22px;padding:5px 20px!important;font-weight:500;cursor:default;background-color:#f7f7f7;font-size:12px;pointer-events:none;color:#1b1b1d;margin-bottom:5px}.layout_cont_middle .typeahead-term-list-ul .result-item-label{width:70%;font-family:HelveticaNeue,Helvetica,Arial,sans-serif}.layout_cont_middle .typeahead-term-list-ul .result-item-label a{padding:5px 20px!important;font-size:12px;font-weight:400}.layout_cont_middle .typeahead-term-list-ul .result-item-label a:hover{background:#ebf2fa!important;width:100%}.layout_cont_middle .typeahead-term-list-ul .search-shortcuts-list{border-top:1px solid #dcdcdc;cursor:pointer;font-size:14px;width:70%}.layout_cont_middle .typeahead-term-list-ul .search-shortcuts-list div{line-height:22px}.layout_cont_middle .typeahead-term-list-ul .search-shortcuts-list a.quickLinks{display:block;color:#0071d0;padding:10px 20px 6px;width:100%;cursor:pointer;text-decoration:none;font-weight:500}.layout_cont_middle .typeahead-term-list-ul .search-shortcuts-list .search-shortcuts-list-header{font-size:14px;line-height:18px;font-family:HelveticaNeue,Helvetica,Arial,sans-serif;padding:5px 20px;cursor:default;font-weight:500;line-height:22px;background:#f7f7f7;margin-bottom:5px}.layout_cont_middle .typeahead-term-list-ul .search-shortcut-list-no-data{border-top:1px solid #dcdcdc;cursor:pointer;font-size:14px;width:100%}.layout_cont_middle .typeahead-term-list-ul .search-shortcut-list-no-data div{line-height:22px}.layout_cont_middle .typeahead-term-list-ul .search-shortcut-list-no-data a.quickLinks{display:block;color:#0071d0;padding:10px 20px 6px;width:100%;cursor:pointer;text-decoration:none;font-weight:500}.layout_cont_middle .typeahead-term-list-ul .search-shortcut-list-no-data .recent-search-term{padding:5px 20px}.layout_cont_middle .typeahead-term-list-ul .search-shortcut-list-no-data .recent-search-term:hover{background-color:#ebf2fa}.layout_cont_middle .typeahead-term-list-ul .search-shortcut-list-no-data .recent-search-term a:hover{border-bottom:2px solid #ee3134}.layout_cont_middle .typeahead-term-list-ul .search-shortcut-list-no-data .search-shortcuts-list-header{font-size:14px;line-height:18px;font-family:HelveticaNeue,Helvetica,Arial,sans-serif;padding:5px 20px;cursor:default;font-weight:500;line-height:22px;background:#f7f7f7;margin-bottom:5px}.layout_cont_middle .typeahead-term-list-ul .typeahead__container__shortcuts_right{position:absolute;min-width:30%;width:fit-content;left:70%;height:100%;background:inherit;border:inherit;border-left:1px solid #e5e5e5;box-sizing:content-box;white-space:nowrap}.layout_cont_middle .search-suggestions{margin-bottom:5px;font-weight:700;cursor:default;background-color:#e5e5e5;font-size:12px}.layout_cont_middle .recent-search-shortcuts-list a.quickLinks{display:block;color:#1e8ae7;padding:10px 0 6px;width:100%;cursor:pointer;text-decoration:none}.layout_cont_middle #searchMagnifyMobile{z-index:1!important;position:absolute!important;right:0!important;top:0!important}.layout_cont_middle #generalSearchInput #clearable{height:22px!important;width:16px!important}.layout_cont_middle [hidden]{display:none!important}@media screen and (max-width:767px){.layout_cont_middle #autoComplete_list_1{padding-inline-start:0;overflow-y:scroll}.layout_cont_middle .typeahead-term-list-ul{width:100%}.layout_cont_middle .typeahead-term-list-ul .typeahead-list-space{width:100%}.layout_cont_middle .typeahead-term-list-ul .result-item-label{width:100%}.layout_cont_middle .typeahead-term-list-ul .search-shortcuts-list{width:100%}.layout_cont_middle .typeahead-term-list-ul .typeahead__container__shortcuts_right{width:100%;left:0;border-top:1px solid #e5e5e5}}@media (min-width:768px) and (max-width:991px){.layout_cont_middle #autoComplete_list_1{padding-inline-start:0;display:flex;flex-direction:column}}@media (min-width:992px) and (max-width:1023px){.layout_cont_middle #autoComplete_list_1{padding-inline-start:0}.layout_cont_middle .typeahead-term-list-ul .typeahead__container__shortcuts_right{width:100%;left:0;border-top:1px solid #e5e5e5}}@media (min-width:1024px) and (max-width:2560px){.layout_cont_middle #autoComplete_list_1{padding-inline-start:0;display:flex;flex-direction:column;min-height:143px}}header .search-container .close{position:absolute;right:36px;width:42px;height:42px;opacity:1;z-index:1001}header .search-container.open{position:inherit}header .search-container.open .close{display:inline-block}header input::-webkit-input-placeholder{font-weight:400;font-size:12px;color:#a2a2a2;text-overflow:ellipsis}#focusAreaSelector{width:auto}.search li,.search ul{margin:0}.search input{font-size:14px;box-shadow:none;height:50px;width:100%;box-sizing:border-box;background:0 0;border-top:1px solid #d8d8d8;border-bottom:1px solid #d8d8d8;border-left:1px solid #f3f3f3;border-right:1px solid #f3f3f3;line-height:28px;margin:0;outline:0;position:relative;z-index:1;text-transform:none;padding:0 48px 0 22px;color:#333}.search input::-ms-clear{display:none;width:0;height:0}.search input:-moz-placeholder,.search input:-ms-input-placeholder,.search input::-moz-placeholder,.search input::-webkit-input-placeholder,.search input::input-placeholder,.search input::placeholder{font-weight:400;font-size:14px;line-height:22px;color:#a2a2a2;text-overflow:ellipsis}.search input .selector-input-adjust{width:100%}.search input.suggested{color:#c9c8c8}.search .search-btn-icon{height:32px;width:32px;margin-top:4px}.search form{margin:0;position:relative;display:inherit}.search form input{height:50px}.search form.active input{height:50px}.search form.active input.selector-input-adjust{width:100%}.search form .searchAutoCompleteProviderSelector{position:relative;width:285px;height:50px;background-color:#f9f9f9;border:0;margin:0;line-height:normal;top:1px;border-radius:0;outline:1px solid #d8d8d8;float:left}.search form .searchAutoCompleteProviderSelector optgroup,.search form .searchAutoCompleteProviderSelector option{background-color:#e5e5e5}.search form .searchAutoCompleteProviderSelector:focus optgroup,.search form .searchAutoCompleteProviderSelector:focus option{background-color:#fff}.search form.providers-enabled input{width:100%}.search button,.search input{font-size:14px;margin-bottom:0;box-shadow:none}.global-commerce-bar{height:60px;position:fixed;top:0;left:0;width:100%;margin:0;background:#fff;z-index:80;font-size:14px;border-bottom:1px solid #eee}.global-commerce-bar .logo{margin:0 0 0 54px!important;text-align:left;padding:15px 0 15px 0}.global-commerce-bar .user-utility{padding:0;margin:0}.global-commerce-bar-spacing{height:0;border-bottom:none}#header-nav-container #header-nav-button{width:50px;padding-left:15px}#search-mobile-button{display:none;position:fixed;width:40px;left:35px;margin-top:-32px}#search-mobile-button-container{width:40px}#search-main.in{min-height:568px}#search-main.in .searchHeading{padding:16px 0 13px 0}#search-main.in .searchHeading p{font-size:16.25px}.clearable{position:absolute;cursor:pointer;top:32px;right:58px;width:16px;z-index:1}.clearable::-ms-clear{display:none;width:0;height:0}.clearable.x{background-position:right 20px center}.clearable.onX{cursor:pointer}.typeahead-group{padding:5px 10px!important}.chosen-container{position:relative;display:inline-block;vertical-align:middle;font-size:14px;-webkit-user-select:none;-moz-user-select:none;-ms-user-select:none;user-select:none}.chosen-container *{-webkit-box-sizing:border-box;box-sizing:border-box}.chosen-container .chosen-drop{position:absolute;top:100%;z-index:1010;width:100%;border:1px solid #aaa;border-top:0;background:#fff;-webkit-box-shadow:0 4px 5px rgba(0,0,0,.15);box-shadow:0 4px 5px rgba(0,0,0,.15);clip:rect(0,0,0,0);clip-path:inset(100% 100%);border-top:0}.chosen-container .chosen-with-drop .chosen-drop{clip:auto;clip-path:none}.chosen-container a{cursor:pointer}.chosen-container .chosen-single .group-name{margin-right:4px;overflow:hidden;white-space:nowrap;text-overflow:ellipsis;font-weight:400;color:#999}.chosen-container .chosen-single .group-name:after{content:":";padding-left:2px;vertical-align:top}.chosen-container .chosen-single.chosen-disabled .chosen-single abbr:hover{background-position:-42px -10px}.chosen-container .chosen-single.chosen-disabled-nosearch .chosen-search{position:absolute;clip:rect(0,0,0,0);clip-path:inset(100% 100%)}.chosen-container .search-choice .group-name{margin-right:4px;overflow:hidden;white-space:nowrap;text-overflow:ellipsis;font-weight:400;color:#999}.chosen-container .search-choice .group-name:after{content:":";padding-left:2px;vertical-align:top}.chosen-container .chosen-results{color:#444;position:relative;overflow-x:hidden;overflow-y:auto;margin:0 4px 4px 0;padding:0 0 0 4px;max-height:350px;-webkit-overflow-scrolling:touch}.chosen-container .chosen-results li{display:none;margin:0;padding:5px 6px;list-style:none;line-height:15px;word-wrap:break-word;-webkit-touch-callout:none}.chosen-container .chosen-results li em{font-style:normal;text-decoration:underline}.chosen-container .chosen-results li.active-result{display:list-item;cursor:pointer}.chosen-container .chosen-results li.disabled-result{display:list-item;color:#ccc;cursor:pointer}.chosen-container .chosen-results li.highlighted{background-color:#3875d7;background-image:-webkit-gradient(linear,left top,left bottom,color-stop(20%,#3875d7),color-stop(90%,#2a62bc));background-image:linear-gradient(#3875d7 20%,#2a62bc 90%);color:#fff}.chosen-container .chosen-results li.no-results{color:#777;display:list-item;background:#f4f4f4}.chosen-container .chosen-results li.group-result{display:list-item;font-weight:700;cursor:default}.chosen-container .chosen-results li.group-option{padding-left:15px}.chosen-container.chosen-with-drop .chosen-drop{clip:auto;-webkit-clip-path:none;clip-path:none}.chosen-container-single .chosen-single{position:relative;display:block;overflow:hidden;text-decoration:none;white-space:nowrap;line-height:24px;height:50px;border-radius:3px 0 0 3px;background-color:#f9f9f9;border:1px solid #d8d8d8;outline:0;padding:0 20px 0 16px;box-shadow:none}.chosen-container-single .chosen-single span{display:block;overflow:hidden;margin-right:26px;text-overflow:ellipsis;white-space:nowrap}.chosen-container-single .chosen-single abbr{position:absolute;top:6px;right:26px;display:block;width:12px;height:12px;background:url(/search/searchbar/resources/images/chosen-sprite.png) -42px 1px no-repeat;font-size:1px}.chosen-container-single .chosen-single abbr:hover{background-position:-42px -10px}.chosen-container-single .chosen-single div{position:absolute;top:0;right:0;display:block;width:18px;height:100%;right:20px}.chosen-container-single .chosen-single div b{display:block;background:url(/search/searchbar/resources/images/chosen-sprite.png) no-repeat 0 2px;background:0 0!important;border-color:#222 transparent transparent transparent;border-style:solid;border-width:5px 4px 0 4px;height:0;left:50%;margin-left:-4px;margin-top:-2px;position:absolute;top:50%;width:0;background:0 0!important}.chosen-container-single .chosen-single>span{line-height:50px}.chosen-container-single .chosen-single-with-deselect span{margin-right:38px}.chosen-container-single .chosen-default{color:#999}.chosen-container-single .chosen-search{position:relative;z-index:1010;margin:0;padding:3px 4px;white-space:nowrap}.chosen-container-single .chosen-search input[type=text]{margin:1px 0;padding:4px 20px 4px 5px;width:100%;height:auto;outline:0;border:1px solid #aaa;background:url(/search/searchbar/resources/images/chosen-sprite.png) no-repeat 100% -20px;font-size:1em;font-family:sans-serif;line-height:normal;border-radius:0}.chosen-container-single .chosen-drop{margin-top:-1px;border-radius:0 0 4px 4px;background-clip:padding-box}.chosen-container-single .chosen-drop{margin-top:-1px;border-radius:0 0 4px 4px;background-clip:padding-box}.chosen-container-single.chosen-disabled .chosen-single abbr:hover{background-position:-42px -10px}.chosen-container-single.chosen-container-single-nosearch .chosen-search{position:absolute;clip:rect(0,0,0,0);-webkit-clip-path:inset(100% 100%);clip-path:inset(100% 100%)}.chosen-container-multi .chosen-choices{position:relative;overflow:hidden;margin:0;padding:0 5px;width:100%;height:auto;border:1px solid #aaa;background-color:#fff;background-image:-webkit-gradient(linear,left top,left bottom,color-stop(1%,#eee),color-stop(15%,#fff));background-image:linear-gradient(#eee 1%,#fff 15%);cursor:text}.chosen-container-multi .chosen-choices li{float:left;list-style:none}.chosen-container-multi .chosen-choices li.search-field{margin:0;padding:0;white-space:nowrap}.chosen-container-multi .chosen-choices li.search-field input[type=text]{margin:1px 0;padding:0;height:25px;outline:0;border:0!important;background:0 0!important;-webkit-box-shadow:none;box-shadow:none;color:#999;font-size:100%;font-family:sans-serif;line-height:normal;border-radius:0;width:25px}.chosen-container-multi .chosen-choices li.search-choice{position:relative;margin:3px 5px 3px 0;padding:3px 20px 3px 5px;border:1px solid #aaa;max-width:100%;border-radius:3px;background-color:#eee;background-image:-webkit-gradient(linear,left top,left bottom,color-stop(20%,#f4f4f4),color-stop(50%,#f0f0f0),color-stop(52%,#e8e8e8),to(#eee));background-image:linear-gradient(#f4f4f4 20%,#f0f0f0 50%,#e8e8e8 52%,#eee 100%);background-size:100% 19px;background-repeat:repeat-x;background-clip:padding-box;-webkit-box-shadow:0 0 2px #fff inset,0 1px 0 rgba(0,0,0,.05);box-shadow:0 0 2px #fff inset,0 1px 0 rgba(0,0,0,.05);color:#333;line-height:13px;cursor:default}.chosen-container-multi .chosen-choices li.search-choice span{word-wrap:break-word}.chosen-container-multi .chosen-choices li.search-choice .search-choice-close{position:absolute;top:4px;right:3px;display:block;width:12px;height:12px;background:url(/search/searchbar/resources/images/chosen-sprite.png) -42px 1px no-repeat;font-size:1px}.chosen-container-multi .chosen-choices li.search-choice .search-choice-close:hover{background-position:-42px -10px}.chosen-container-multi .chosen-choices li.search-choice-disabled{padding-right:5px;border:1px solid #ccc;background-color:#e4e4e4;background-image:-webkit-gradient(linear,left top,left bottom,color-stop(20%,#f4f4f4),color-stop(50%,#f0f0f0),color-stop(52%,#e8e8e8),to(#eee));background-image:linear-gradient(#f4f4f4 20%,#f0f0f0 50%,#e8e8e8 52%,#eee 100%);color:#666}.chosen-container-multi .chosen-choices li.search-choice-focus{background:#d4d4d4}.chosen-container-multi .chosen-choices li.search-choice-focus .search-choice-close{background-position:-42px -10px}.chosen-container-multi .chosen-results{margin:0;padding:0}.chosen-container-multi .chosen-drop .result-selected{display:list-item;color:#ccc;cursor:default}.chosen-container-multi li .search-field{margin:0;padding:0;white-space:nowrap}.chosen-container-multi li .search-field input[type=text]{margin:1px 0;padding:0;height:25px;outline:0;border:0!important;background:0 0!important;-webkit-box-shadow:none;box-shadow:none;color:#999;font-size:100%;font-family:sans-serif;line-height:normal;border-radius:0;width:25px}.chosen-container-multi li.search-choice{position:relative;margin:3px 5px 3px 0;padding:3px 20px 3px 5px;border:1px solid #aaa;max-width:100%;border-radius:3px;background-color:#eee;background-image:-webkit-gradient(linear,left top,left bottom,color-stop(20%,#f4f4f4),color-stop(50%,#f0f0f0),color-stop(52%,#e8e8e8),to(#eee));background-image:linear-gradient(#f4f4f4 20%,#f0f0f0 50%,#e8e8e8 52%,#eee 100%);background-size:100% 19px;background-repeat:repeat-x;background-clip:padding-box;-webkit-box-shadow:0 0 2px #fff inset,0 1px 0 rgba(0,0,0,.05);box-shadow:0 0 2px #fff inset,0 1px 0 rgba(0,0,0,.05);color:#333;line-height:13px;cursor:default}.chosen-container-multi li.search-choice span{word-wrap:break-word}.chosen-container-multi li.search-choice .search-choice-close{position:absolute;top:4px;right:3px;display:block;width:12px;height:12px;background:url(/search/searchbar/resources/images/chosen-sprite.png) -42px 1px no-repeat;font-size:1px}.chosen-container-multi li.search-choice .search-choice-close:hover{background-position:-42px -10px}.chosen-container-multi li.search-choice-disabled{padding-right:5px;border:1px solid #ccc;background-color:#e4e4e4;background-image:-webkit-gradient(linear,left top,left bottom,color-stop(20%,#f4f4f4),color-stop(50%,#f0f0f0),color-stop(52%,#e8e8e8),to(#eee));background-image:linear-gradient(#f4f4f4 20%,#f0f0f0 50%,#e8e8e8 52%,#eee 100%);color:#666}.chosen-container-multi li.search-choice-focus{background:#d4d4d4}.chosen-container-multi li.search-choice-focus .search-choice-close{background-position:-42px -10px}.chosen-container-multi .chosen-results{margin:0;padding:0}.chosen-container-active .chosen-choices{border:1px solid #5897fb;-webkit-box-shadow:0 0 5px rgba(0,0,0,.3);box-shadow:0 0 5px rgba(0,0,0,.3)}.chosen-container-active .chosen-choices li.search-field input[type=text]{color:#222!important}.chosen-container-active .chosen-choices{border:1px solid #5897fb;-webkit-box-shadow:0 0 5px rgba(0,0,0,.3);box-shadow:0 0 5px rgba(0,0,0,.3)}.chosen-container-active .chosen-choices li.search-field input[type=text]{color:#222!important}.chosen-container-active.chosen-with-drop .chosen-single{border:1px solid #aaa;border-bottom-right-radius:0;border-bottom-left-radius:0;box-shadow:0 1px 0 #fff inset}.chosen-container-active.chosen-with-drop .chosen-single div{border-left:none;background:0 0}.chosen-container-active.chosen-with-drop .chosen-single div b{background-position:-18px 2px}.chosen-container-active.chosen-with-drop .chosen-single{border:1px solid #aaa;border-bottom-right-radius:0;border-bottom-left-radius:0;box-shadow:0 1px 0 #fff inset}.chosen-container-active.chosen-with-drop .chosen-single div{border-left:none;background:0 0}.chosen-container-active.chosen-with-drop .chosen-single div b{background-position:-18px 2px}.chosen-disabled{opacity:.5!important;cursor:default}.chosen-disabled .chosen-single{cursor:default}.chosen-disabled .chosen-choices .search-choice .search-choice-close{cursor:default}.chosen-rtl{text-align:right}.chosen-rtl .chosen-single{overflow:visible;padding:0 8px 0 0}.chosen-rtl .chosen-single span{margin-right:0;margin-left:26px;direction:rtl}.chosen-rtl .chosen-single div{right:auto;left:3px}.chosen-rtl .chosen-single abbr{right:auto;left:26px}.chosen-rtl .chosen-single-with-deselect span{margin-left:38px}.chosen-rtl .chosen-choices li{float:right}.chosen-rtl .chosen-choices li.search-choice{margin:3px 5px 3px 0;padding:3px 5px 3px 19px}.chosen-rtl .chosen-choices li.search-field input[type=text]{direction:rtl}.chosen-rtl .chosen-choices li.search-choice{margin:3px 5px 3px 0;padding:3px 5px 3px 19px}.chosen-rtl .chosen-choices li.search-choice .search-choice-close{right:auto;left:4px}.chosen-rtl .chosen-results li.group-option{padding-right:15px;padding-left:0}.chosen-rtl .chosen-search input[type=text]{padding:4px 5px 4px 20px;background:url(/search/searchbar/resources/resources/images/chosen-sprite.png) no-repeat -30px -20px;direction:rtl}.chosen-rtl.chosen-container-single .chosen-results{margin:0 0 4px 4px;padding:0 4px 0 0}.chosen-rtl.chosen-container-single .chosen-single div b{background-position:6px 2px}.chosen-rtl.chosen-container-active.chosen-with-drop .chosen-single div{border-right:none}.chosen-rtl.chosen-container-single.chosen-with-drop .chosen-single div b{background-position:-12px 2px}.chosen-drop{border-top:1px solid #d8d8d8}.chosen-drop .chosen-results{margin:0!important;padding:0!important;border-top:1px solid #dcdcdc}.chosen-drop .chosen-results .active-result.result-selected,.chosen-drop .chosen-results .active-result.result-selected.highlighted{background-repeat:no-repeat;background-size:10% 100%;background-position:left;color:#fff!important;background-color:#007fff!important;background-image:none!important}.chosen-drop .chosen-results .group-result{border-top:1px solid #dcdcdc;color:#a2a2a2}.chosen-drop .chosen-results li.group-option{padding-left:1.5rem;color:#000;padding-top:5px;padding-bottom:5px;font-size:13px}.chosen-drop .chosen-results li.group-option.highlighted{color:#000!important;background:#ebf2fa!important}.chosen-drop .chosen-results .active-result.highlighted{color:#000!important;background:#ebf2fa!important}.searchRemoveHide{display:none!important}.typeahead-span{margin-left:0!important}.typeahead-term-list{border-bottom:1px solid #dcdcdc}.header-typeahead{left:2px;z-index:500;overflow:hidden;position:absolute;box-shadow:0 2px 2px rgba(0,0,0,.1);display:none;margin-left:-2px;outline:0;width:100%;background:#fff;margin-top:0}.header-typeahead a{cursor:pointer}.header-typeahead .typeahead-terms{float:left;position:relative;z-index:508;overflow:hidden;font-size:12px;width:100%;overflow-y:auto;max-height:510px}.header-typeahead .typeahead-group{background:#f7f7f7;border-radius:2px;padding:5px 20px!important}.header-typeahead .typeahead-span{margin-left:0}.header-typeahead .typeahead-span strong{font-weight:400;color:gray}.header-typeahead .typeahead-flyout{float:left;width:442px;height:300px;background:#f8f8f8;border-left:1px solid #d8d8d8;padding:10px;position:relative;left:-1px;z-index:501;overflow:hidden}.header-typeahead ul{list-style:none}.header-typeahead .typeahead-term-list{border-bottom:1px solid #dcdcdc}.header-typeahead .typeahead-term-list li{display:block;line-height:22px;padding:5px 20px;width:100%!important}.header-typeahead .typeahead-term-list li a{display:block;width:100%!important}.header-typeahead .typeahead-term-list li a.typeahead-term{display:inline-block;color:#333;text-overflow:ellipsis;overflow:hidden;white-space:nowrap;vertical-align:middle;border-bottom:2px solid transparent;font-weight:500}.header-typeahead .typeahead-term-list li.typeahead-ignore{padding:0;margin:0}.header-typeahead .typeahead-term-list li.highlighted{background:#ebf2fa!important}.header-typeahead .typeahead-term-list a.typeahead-term.active span{border-bottom:0}.header-typeahead .typeahead-term-list a.typeahead-term.active span .title-text{border-bottom:0}.header-typeahead span.typeahead-hr{display:block;border-bottom:1px solid #d8d8d8;margin-top:10px;margin-bottom:10px}.header-typeahead .title-text{color:#0071d0}.header-typeahead .search-suggestions{padding:10px;margin-bottom:5px;font-weight:700;cursor:default;background-color:#e5e5e5}#header-typeahead{overflow-x:hidden;z-index:500;overflow-y:scroll;width:100%;background:#fff;position:absolute;box-shadow:0 2px 2px rgba(0,0,0,.1);display:none;outline:0;max-height:calc(100vh - 120px)}#header-typeahead a{cursor:pointer}#header-typeahead ul{list-style:none;padding-inline-start:0}#header-typeahead span.typeahead-hr{display:block;border-bottom:1px solid #d8d8d8;margin-top:10px;margin-bottom:10px}#header-typeahead .title-text{color:#0071d0}#header-typeahead .search-shortcut-list li a.quickLinks,#header-typeahead .typeahead-term-list li a.typeahead-term{display:inline-block;color:#333;text-overflow:ellipsis;overflow:hidden;white-space:nowrap;vertical-align:middle;border-bottom:2px solid transparent;font-weight:500}#header-typeahead .search-suggestions{padding:10px;margin-bottom:5px;font-weight:700;cursor:default;background-color:#e5e5e5}#header-typeahead .search-shortcut-list{border-top:1px solid #dcdcdc}#header-typeahead .search-shortcut-list li{display:block;line-height:22px;width:100%!important}#header-typeahead .search-shortcut-list li.highlighted{background:#ebf2fa!important}#header-typeahead .search-shortcut-list li.typeahead-ignore{padding:0;margin:0}#header-typeahead .search-shortcut-list li a{display:block;width:100%!important}#header-typeahead .search-shortcut-list li a.quickLinks{color:#0071d0;padding:10px 20px 6px}#header-typeahead .typeahead-terms{float:left;width:200px;position:relative;z-index:508;overflow:hidden;font-size:12px}#header-typeahead .typeahead-group{background:#f7f7f7;border-radius:2px;padding:5px 20px!important}#header-typeahead .typeahead-span strong{font-weight:400;color:gray}#header-typeahead .typeahead-flyout{float:left;width:442px;height:300px;background:#f8f8f8;border-left:1px solid #d8d8d8;padding:10px;position:relative;left:-1px;z-index:501;overflow:hidden}#header-typeahead .typeahead-term-list li{display:block;line-height:22px;padding:5px 20px;width:100%!important}#header-typeahead .typeahead-term-list li.highlighted{background:#ebf2fa!important}#header-typeahead .typeahead-term-list li.typeahead-ignore{padding:0;margin:0}#header-typeahead .typeahead-term-list li a{display:block;width:100%!important}#header-typeahead .typeahead-term-list li a.quickLinks{color:#0071d0}#header-typeahead .typeahead-term-list a.typeahead-term.active span{border-bottom:0}#header-typeahead .typeahead-term-list a.typeahead-term.active span .title-text{border-bottom:0}#header-typeahead-suggested{display:none;color:#aaa;-webkit-text-fill-color:#aaa;position:absolute;top:0;right:1px;left:0;bottom:1px;background:0 0;z-index:0;width:100%}#header-typeahead-suggested.active{display:block}#header-typeahead-input-container{width:100%;height:50px}.ac_results{box-shadow:0 1px 2px rgba(0,0,0,.1);background:#fff;border:1px solid #d8d8d8;padding:10px;z-index:1;right:50px!important;top:34px!important}.ac_results li{color:#555;cursor:pointer;padding:2px 5px}.ac_results li:hover{background:#f8f8f8;color:#007ed5;cursor:pointer;text-decoration:none}.ac_results li.ac_over{background:#f8f8f8;color:#007ed5;cursor:pointer;text-decoration:none}.ac_results li.ac_skip{background:#fff;border-bottom:1px solid #d8d8d8;color:#1a2155;cursor:text;display:block;font-weight:700;padding:0 5px 5px 5px;margin-bottom:5px;text-decoration:none}.ac_results li.ac_skip:hover{background:#fff;border-bottom:1px solid #d8d8d8;color:#1a2155;cursor:text;display:block;font-weight:700;padding:0 5px 5px 5px;margin-bottom:5px;text-decoration:none}.ac_results li.ac_skip em{font-style:normal}.flyout-recent-searches{display:none}.flyout-recent-searches li{display:block;line-height:22px;padding:0 20px}.flyout-recent-searches li.term a{display:inline-block;color:#333;text-overflow:ellipsis;overflow:hidden;white-space:nowrap;border-bottom:2px solid transparent;width:100%!important}.flyout-recent-searches li.term a:hover{background-color:#ebf2fa}.flyout-recent-searches li.recent-searches{padding:20px;margin-bottom:5px;cursor:default;background-color:#f9f9f9;font-weight:700}.flyout-recent-searches li.recent-searches em{font-style:normal}.flyout-typeahead{display:none}.searchAutoCompleteProviderSelectorIE78{width:203px;height:52px;background-color:#f9f9f9;border:solid 0 #cdcccc;outline:1px solid #d8d8d8;margin:0;float:left;padding-top:4px;line-height:normal;z-index:2;left:4px;padding-bottom:3px;position:absolute;top:4px}.searchAutoCompleteProviderSelectorIE78:focus{width:auto;background-color:#fff}.msie78Search{width:190px}.ie8 .header_row_1.layout_cont_middle{clear:both!important}.ie8 .header_row_2.layout_cont_middle{margin-left:285px!important}.ie8 #meganav-content{display:block!important}.ie8 .hide-meganav #meganav-content{display:none!important}@media only screen and (-webkit-min-device-pixel-ratio:1.5){.chosen-container .chosen-results-scroll-down span{background-image:url(/search/searchbar/resources/images/chosen-sprite@2x.png)!important;background-size:52px 37px!important;background-repeat:no-repeat!important}.chosen-container .chosen-results-scroll-up span{background-image:url(/search/searchbar/resources/images/chosen-sprite@2x.png)!important;background-size:52px 37px!important;background-repeat:no-repeat!important}.chosen-container-multi .chosen-choices .search-choice .search-choice-close{background-image:url(/search/searchbar/resources/images/chosen-sprite@2x.png)!important;background-size:52px 37px!important;background-repeat:no-repeat!important}.chosen-container-single .chosen-search input[type=text]{background-image:url(/search/searchbar/resources/images/chosen-sprite@2x.png)!important;background-size:52px 37px!important;background-repeat:no-repeat!important}.chosen-container-single .chosen-single abbr{background-image:url(/search/searchbar/resources/images/chosen-sprite@2x.png)!important;background-size:52px 37px!important;background-repeat:no-repeat!important}.chosen-container-single .chosen-single div b{background-image:url(/search/searchbar/resources/images/chosen-sprite@2x.png)!important;background-size:52px 37px!important;background-repeat:no-repeat!important}.chosen-rtl .chosen-search input[type=text]{background-image:url(/search/searchbar/resources/images/chosen-sprite@2x.png)!important;background-size:52px 37px!important;background-repeat:no-repeat!important}}@media only screen and (min-resolution:144dpi){.chosen-container .chosen-results-scroll-down span{background-image:url(/search/searchbar/resources/images/chosen-sprite@2x.png)!important;background-size:52px 37px!important;background-repeat:no-repeat!important}.chosen-container .chosen-results-scroll-up span{background-image:url(/search/searchbar/resources/images/chosen-sprite@2x.png)!important;background-size:52px 37px!important;background-repeat:no-repeat!important}.chosen-container-multi .chosen-choices .search-choice .search-choice-close{background-image:url(/search/searchbar/resources/images/chosen-sprite@2x.png)!important;background-size:52px 37px!important;background-repeat:no-repeat!important}.chosen-container-single .chosen-search input[type=text]{background-image:url(/search/searchbar/resources/images/chosen-sprite@2x.png)!important;background-size:52px 37px!important;background-repeat:no-repeat!important}.chosen-container-single .chosen-single abbr{background-image:url(/search/searchbar/resources/images/chosen-sprite@2x.png)!important;background-size:52px 37px!important;background-repeat:no-repeat!important}.chosen-container-single .chosen-single div b{background-image:url(/search/searchbar/resources/images/chosen-sprite@2x.png)!important;background-size:52px 37px!important;background-repeat:no-repeat!important}.chosen-rtl .chosen-search input[type=text]{background-image:url(/search/searchbar/resources/images/chosen-sprite@2x.png)!important;background-size:52px 37px!important;background-repeat:no-repeat!important}}@media only screen and (min-resolution:1.5dppx){.chosen-container .chosen-results-scroll-down span{background-image:url(/search/searchbar/resources/images/chosen-sprite@2x.png)!important;background-size:52px 37px!important;background-repeat:no-repeat!important}.chosen-container .chosen-results-scroll-up span{background-image:url(/search/searchbar/resources/images/chosen-sprite@2x.png)!important;background-size:52px 37px!important;background-repeat:no-repeat!important}.chosen-container-multi .chosen-choices .search-choice .search-choice-close{background-image:url(/search/searchbar/resources/images/chosen-sprite@2x.png)!important;background-size:52px 37px!important;background-repeat:no-repeat!important}.chosen-container-single .chosen-search input[type=text]{background-image:url(/search/searchbar/resources/images/chosen-sprite@2x.png)!important;background-size:52px 37px!important;background-repeat:no-repeat!important}.chosen-container-single .chosen-single abbr{background-image:url(/search/searchbar/resources/images/chosen-sprite@2x.png)!important;background-size:52px 37px!important;background-repeat:no-repeat!important}.chosen-container-single .chosen-single div b{background-image:url(/search/searchbar/resources/images/chosen-sprite@2x.png)!important;background-size:52px 37px!important;background-repeat:no-repeat!important}.chosen-rtl .chosen-search input[type=text]{background-image:url(/search/searchbar/resources/images/chosen-sprite@2x.png)!important;background-size:52px 37px!important;background-repeat:no-repeat!important}}@media (max-width:979px){.search form{background:#fff;height:auto;border:none!important;margin-top:0;margin:auto;width:100%}.search form input{box-sizing:border-box;line-height:40px;height:50px;width:100%!important;-webkit-appearance:none;-moz-appearance:none;appearance:none;border:1px solid #dcdcdc}.search form input.active input{height:50px}.search form input.selector-input-adjust{width:100%}.search form .search-button{display:none;position:absolute;top:273px;width:100%!important;height:46px;padding-top:0;color:#fff;line-height:46px;border-radius:3px 3px!important;margin:auto;left:0;right:0}.search form .search-button:hover{cursor:pointer}.search form .search-button img{display:none}.search form .search-btn-icon{right:14px;position:absolute;top:24px}.search form .searchAutoCompleteProviderSelector{top:0;width:100%!important;line-height:40px;height:40px;float:none}.search-container .search{display:none}.search-container.open .search{display:block;visibility:visible;opacity:1;position:fixed;z-index:1000;top:0;left:0;height:100%;width:100%;background-color:#fff;animation:fadeIn .5s}.container-modifier{padding:0!important}.typeahead-group{padding:5px 30px!important}.general_search.layout_cont_middle{margin-right:0}.header_row_2.layout_cont_left{width:95%;float:none;margin:auto;padding:0 15px 0 15px!important}.header_row_2.layout_cont_middle{width:95%;margin:auto;padding:0 15px 0 15px!important}.layout_cont_right{float:none;width:100%}#mobile-search-button-container{float:right;width:50px;height:60px;border-left:1px solid #eee;border-right:1px solid #eee}#search-mobile-button{display:block;height:60px;width:50px;border:none;background:0 0;background-image:url(/etc/designs/lifetech/clientlibs/base/img/icon-search-black.svg);background-repeat:no-repeat;background-position:center;position:relative;left:0;margin-top:0}#search-mobile-button.active{border-bottom:3px solid #ee3134;background-image:url(/etc/designs/lifetech/clientlibs/base/img/icon-cross-black.svg);background-repeat:no-repeat;background-size:18px 18px}#focusAreaSelector{width:100%!important;margin:auto}#search-main.in{display:block;overflow:auto;overflow-x:hidden;position:fixed;z-index:200;bottom:0;top:61px;left:0;right:0;background:#fff}#search-main.in .searchHeading{display:block!important;padding:40px 0 24px 0;font-size:25.35px;color:#a2a2a2;text-align:center;font-weight:400}#search-main.in .searchHeading span{color:#333;font-weight:700}.global-commerce-bar .logo img{height:28px}#header-typeahead-input-container{width:100%;height:60px;left:0;right:0;margin:auto;padding:16px 0 16px 0;background:#fff}#header-typeahead{height:calc(100vh - 280px);width:100%;top:66px;margin:auto;left:0;right:0}}@media (min-width:992px){.header_row_2.layout_cont_wrapper{display:flex;flex-direction:row}.header_row_2.layout_cont_left,.header_row_2.layout_cont_middle{min-width:200px;padding:0!important}.header_row_2.layout_cont_middle{margin-left:0;width:100%}.search form{display:flex;width:100%}.searchHeading{display:none}.searchMagnifyMobile{display:none}header .search-container .search .search-button .search-text{display:none}.clearable{top:15px;right:24px}}.searchHeading p{padding:72px 36px 24px;font-size:22px;font-weight:500;line-height:28px;color:#92929e}.searchHeading p span{color:#000}.general_search.layout_cont_middle{order:-1;width:100%;margin-right:0;position:relative}header .search-layout .close{z-index:1001}.gsh-global-search-form-container .type-ahead-ctnr .keyword-container .dropdown-menu.ng-hide{display:none}.gsh-global-search-form-container .tf-filter-condensed-ctnr .tf-filter-box{height:48px!important}header .gsh-global-search-form-container .tf-filter-condensed-ctnr .filter-drop-down-ctnr{min-width:210px;margin-top:0;width:100%}#header-offer-bar{height:0;display:none}body{margin-top:60px}body .main-top-spacing{margin-top:60px}body .search-bg{top:60px}body.hide-header{margin-top:0}body.hide-header header{display:none}body.has-messaging-bar{margin-top:106px}body.has-messaging-bar .main-top-spacing{margin-top:106px}body.has-messaging-bar .search-bg{top:106px}body.spectraviewer{margin-top:60px}body.bootstrap-noconflict{padding-top:10px}@media (min-width:576px){#header-offer-bar{height:35px;display:block}body{margin-top:96px}body .main-top-spacing{margin-top:96px}body .search-bg{top:96px}body.has-messaging-bar{margin-top:141px}body.has-messaging-bar .main-top-spacing{margin-top:141px}body.has-messaging-bar .search-bg{top:141px}}@media (min-width:992px){body{margin-top:112px}body .main-top-spacing{margin-top:112px}body .search-bg{top:112px}body.has-messaging-bar{margin-top:157px}body.has-messaging-bar .main-top-spacing{margin-top:157px}body.has-messaging-bar .search-bg{top:157px}body.spectraviewer{margin-top:76px}}.clear:after,.clear:before,.clearfix:after,.clearfix:before,.group:after,.group:before,.result:after,.result:before{display:table;content:"";line-height:0}.clear:after,.clearfix:after,.group:after,.result:after{clear:both}.hide-text{font:0/0 a;color:transparent;text-shadow:none;background-color:transparent;border:0}.input-block-level{-webkit-box-sizing:border-box;-moz-box-sizing:border-box;box-sizing:border-box;display:block;width:100%;min-height:36px}#promoBar .promo-bar-snippet{background:#f3f3f3;line-height:35px;height:35px;font-size:15px;text-align:center;vertical-align:middle;display:block}#promoBar .promo-bar-snippet strong{color:#ee3134}#promoBar .promo-bar-snippet em{font-style:inherit;color:#c8c8c8;font-family:Arial,sans-serif;font-size:28px;vertical-align:bottom}#promoBar a.promo-bar-snippet{color:#000}#promoBar a.promo-bar-snippet:hover{color:#fff;background:#c8c8c8}#promoBar a.promo-bar-snippet:hover a,#promoBar a.promo-bar-snippet:hover em,#promoBar a.promo-bar-snippet:hover strong{color:#fff}#promoBar .promo-bar-snippet{overflow-x:auto;overflow-y:hidden;white-space:nowrap;padding:0 10px}#promoBar .promo-bar-snippet #promoBarContainer{padding:0 10px}#promoBar .promo-bar-snippet::-webkit-scrollbar{display:none}@media (max-width:767px){#promoBar .promo-bar-snippet{margin:0 -10px}}@media (max-width:479px){#promoBar{display:none!important}}#landscapeBanner{position:fixed;bottom:0;width:100%;z-index:9999}#landscapeBanner.author{position:relative;bottom:unset}#landscapeBanner #landscapeBannerContainer{background:#f3f3f3;border:1px solid #dcdcdc;height:60px;display:block}#landscapeBanner #landscapeBannerContainer #landscapeBannerContent{margin:auto}#landscapeBanner #landscapeBannerContainer #landscapeBannerContent .landscape-banner-snippet{color:#222;font-size:22px;font-weight:500;line-height:60px;text-align:center;vertical-align:middle;display:block;font-family:HelveticaNeue,Helvetica,Roboto,"Segoe UI",Arial,sans-serif}#landscapeBanner #landscapeBannerContainer #landscapeBannerContent .landscape-banner-snippet #lb-button{margin-left:30px;font-size:14px;margin-bottom:5px;border-radius:3px!important}#landscapeBanner #landscapeBannerContainer #landscapeBannerContent .landscape-banner-snippet #lb-button.btn-lb-light-gray{color:#1e8ae7}#landscapeBanner #landscapeBannerContainer #landscapeBannerContent .landscape-banner-snippet #lb-button.btn-lb-light-gray:hover{background-color:#fff;border:1px solid #1e8ae7}#landscapeBanner #landscapeBannerContainer #landscapeBannerContent .landscape-banner-button{background:#f3f3f3;position:absolute;top:1px;right:40px;width:60px;height:62px;border:none}@media only screen and (max-width:979px) and (min-width:480px){#landscapeBanner{left:0}#landscapeBanner #landscapeBannerContainer #landscapeBannerContent{margin-top:11px}#landscapeBanner #landscapeBannerContainer #landscapeBannerContent .landscape-banner-snippet{overflow-wrap:break-word;margin-left:1rem;line-height:normal;font-size:18px;width:85%}#landscapeBanner #landscapeBannerContainer #landscapeBannerContent .landscape-banner-snippet #lb-button{margin-left:20px}}@media only screen and (max-width:479px){#landscapeBanner{left:0}#landscapeBanner #landscapeBannerContainer{height:60px}#landscapeBanner #landscapeBannerContainer #landscapeBannerContent{width:auto;margin-top:14px;margin-left:1rem}#landscapeBanner #landscapeBannerContainer #landscapeBannerContent .landscape-banner-snippet{overflow-wrap:break-word;margin-left:.5rem;line-height:normal;font-size:14px;text-align:left;width:80%}#landscapeBanner #landscapeBannerContainer #landscapeBannerContent .landscape-banner-snippet #lb-button{display:initial;padding:unset;border:none;background:unset;margin-left:8px}#landscapeBanner #landscapeBannerContainer #landscapeBannerContent .landscape-banner-snippet #lb-button::after{content:"\203A"}#landscapeBanner #landscapeBannerContainer #landscapeBannerContent .landscape-banner-button{right:1px;border:none}}@media only screen and (min-width:980px){#pdpOfferContainer{height:192px;border-style:solid;border-width:thin;border-color:#dcdcdc}#pdpOfferContainer.author{position:relative;bottom:unset}#pdpOfferContainer #pdpOffer-Content #pdp-image{width:164px;height:132px;padding:5px 5px 8px 7px;float:right}#pdpOfferContainer button{width:auto;height:30px;white-space:nowrap;border-radius:3px;background-color:#555759;font-family:"Helvetica Neue",Helvetica,Roboto,"Segoe UI",Arial,sans-serif;font-size:11px;font-weight:700;font-style:normal;font-stretch:normal;line-height:normal;letter-spacing:normal;text-align:center;color:#fff;margin-left:13px;margin-bottom:24px;position:relative;margin-right:90%;text-decoration:none}#pdpOfferContainer .close{width:12px;height:22px;opacity:.5;color:#000;background-color:#fff;float:right;font-size:20px;font-weight:700;line-height:22px;margin-right:15px}}@media only screen and (min-width:480px) and (max-width:767px){#pdpOfferContainer{height:192px;border-style:solid;border-width:thin;border-color:#dcdcdc}#pdpOfferContainer.author{position:relative;bottom:unset}#pdpOfferContainer #pdpOffer-Content #pdp-image{width:164px;height:132px;padding:5px 5px 8px 7px;float:right}#pdpOfferContainer button{width:auto;height:30px;white-space:nowrap;border-radius:3px;background-color:#555759;font-family:"Helvetica Neue",Helvetica,Roboto,"Segoe UI",Arial,sans-serif;font-size:11px;font-weight:700;font-style:normal;font-stretch:normal;line-height:normal;letter-spacing:normal;text-align:center;color:#fff;margin-left:13px;margin-bottom:24px;position:relative;margin-right:90%;text-decoration:none}#pdpOfferContainer .close{width:12px;height:22px;opacity:.5;color:#000;background-color:#fff;float:right;font-size:20px;font-weight:700;line-height:22px;margin-right:15px}}@media only screen and (min-width:767px) and (max-width:979px){#pdpOfferContainer{height:192px;border-style:solid;border-width:thin;border-color:#dcdcdc}#pdpOfferContainer.author{position:relative;bottom:unset}#pdpOfferContainer #pdpOffer-Content #pdp-image{visibility:hidden;width:0;height:0;display:none}#pdpOfferContainer button{width:auto;height:30px;white-space:nowrap;border-radius:3px;background-color:#555759;font-family:"Helvetica Neue",Helvetica,Roboto,"Segoe UI",Arial,sans-serif;font-size:11px;font-weight:700;font-style:normal;font-stretch:normal;line-height:normal;letter-spacing:normal;text-align:center;color:#fff;margin-left:13px;margin-bottom:24px;position:relative;margin-right:90%;text-decoration:none}#pdpOfferContainer .close{width:12px;height:22px;opacity:.5;color:#000;background-color:#fff;float:right;font-size:20px;font-weight:700;line-height:22px;margin-right:15px}}@media only screen and (max-width:479px){#pdpOfferContainer{height:192px;border-style:solid;border-width:thin;border-color:#dcdcdc}#pdpOfferContainer.author{position:relative;bottom:unset}#pdpOfferContainer #pdpOffer-Content #pdp-image{visibility:hidden;width:0;height:0;display:none}#pdpOfferContainer button{width:auto;height:30px;white-space:nowrap;border-radius:3px;background-color:#555759;font-family:"Helvetica Neue",Helvetica,Roboto,"Segoe UI",Arial,sans-serif;font-size:11px;font-weight:700;font-style:normal;font-stretch:normal;line-height:normal;letter-spacing:normal;text-align:center;color:#fff;margin-left:13px;margin-bottom:24px;position:relative;margin-right:90%;text-decoration:none}#pdpOfferContainer .close{width:12px;height:22px;opacity:.5;color:#000;background-color:#fff;float:right;font-size:20px;font-weight:700;line-height:22px;margin-right:15px}}#searchOffer-container{background-color:#ebf2fa;padding:10px 10px 1px 10px;position:relative;margin-bottom:10px}#searchOffer-container.author{position:relative;bottom:unset}#searchOffer-container #searchOffer-title{display:inline-block;margin:0 0 8px 0;line-height:19px;font-family:"Helvetica Neue-Medium",Helvetica,Arial,sans-serif;text-decoration:none;font-size:16px;color:#1e8ae7}#searchOffer-container #searchOffer-title a:hover{color:#005daa}#searchOffer-container #search-subtitle{display:inline-block;font-family:"Helvetica Neue-Medium",Helvetica,Arial,sans-serif;font-size:14px;line-height:17px;margin-bottom:12px}.overlay-modal-body{max-width:950px;margin:0 auto;display:inline-block;padding-left:10px;display:none}@media only screen and (max-width:767px){#tf-cart-overlay-1 p#cart-text{padding-top:14px;padding-left:13px;float:left;text-align:left}#tf-cart-overlay-1 .chevroncont{margin-top:0;padding-top:0;float:left;padding-left:13px}.overlay-modal-body img{max-width:90%;height:auto}}@media only screen and (max-width:479px){#tf-cart-overlay-1{padding-right:10%}} /*# sourceMappingURL=header.min.css.map */ </style>  <script type="text/javascript"> window.performance && window.performance.mark && window.performance.mark("header_1"); </script> <script type="text/javascript" src="/store/global-header-footer-static/tf/js/utilities.min.468bd07150dbbf.js" async></script>  <script type="text/javascript"> window.performance && window.performance.mark && window.performance.mark("header_2"); </script>  <script data-inline-file-name='globalFunctions.js' data-inline-site='tf'>/* Hash: 468bd07150dbbf Source: /tf/js/dist/globalFunctions.js */ function getCookie(key) { var result = ""; var cookies = document.cookie ? document.cookie.split('; ') : []; for (var i = 0, l = cookies.length; i < l; i++) { var parts = cookies[i].split('='); var name = decodeURIComponent(parts.shift()); var cookie = parts.join('='); // Prevent storing or parsing of a cookie that we couldn't decode. if ( cookie && key === name ) { // removes surrounding quotes if ( cookie.indexOf('"') === 0) { // This is a quoted cookie as according to RFC2068, unescape... cookie = cookie.slice(1, -1).replace(/\\"/g, '"').replace(/\\\\/g, '\\'); } // parse utf8 characters // cannot use decode_utf8 because it will escape the value try { cookie = decodeURIComponent(cookie); } catch (e){ } result = cookie; // we found it, don't bother looking at other cookies break; } } return result; }; var setCookie = function(name, value, numDays){ if ( !numDays ) numDays = 31; var expires = new Date(); expires.setTime(expires.getTime() + (1000 * 60 * 60 * 24 * numDays)); document.cookie = name+ '=' + escape(value) + '; path=/; expires=' + expires.toGMTString() + '; domain=.' + this.getMasterDomain() + ';'; }; /** * get the domain based on a set of rules */ var getMasterDomain = function () { // default the domain var masterDomain = 'thermofisher.com'; // check for alternate domain. Upon match, the match[1] = domain_name, match[2] = domain_suffix var regexMatch = document.location.hostname.match(/\.(thermofisher)\.(cn)/i); if (regexMatch !== null) { // add the parts of the match. (match[1] = domain_name) + (match[2] = domain_suffix) masterDomain = regexMatch[1] + '.' + regexMatch[2]; } return masterDomain; }; var decode_utf8 = function ( s ){ try { s= decodeURIComponent( escape( s ) ); } catch ( err ) {} return s; }; var isResponsive = function() { // Even if we have viewport tag, IE8 wont support. // This can go away.. eventually // Lazy IE8 check var isIE8 = window.attachEvent && !window.addEventListener; return !isIE8 && document.querySelectorAll('meta[name="viewport"]').length > 0; }; var getCurrentViewportSize = function() { var which = 'lg'; if ( isResponsive() ) { which = 'xl'; var breakpoints = { lg: 1200, md: 980, sm: 768, xs: 480 }; var width = window.innerWidth; for ( var w in breakpoints ) { if ( width < breakpoints[w] ) which = w; } } return which; }; function getQueryParam (param) { var index, key, value, hash; var hashes = window.location.href.slice(window.location.href.indexOf('?') + 1).split('&'); for (index = 0; index < hashes.length; index++) { hash = hashes[index].split('='); key = hash[0]; value = hash[1]; if (key.toUpperCase() === param.toUpperCase()) return value; } return ''; };</script>  <script type="text/javascript"> window.performance && window.performance.mark && window.performance.mark("header_3"); </script>  <script type="text/javascript"> window.performance && window.performance.mark && window.performance.mark("header_4"); </script>  <div id="header-offer-bar"> <div class="interactoffers"> <div class="dynamic-offer" id="tf-headerfooter-hb" data-placement-type="headerfooter" data-placement-code="hb" data-default-snippet=""> </div> </div> </div>  <script type="text/javascript"> window.performance && window.performance.mark && window.performance.mark("header_5"); </script> <script type="text/javascript"> var globalProviderConfig = { countryCode:'sg', langCode:'en', focusAreaPath:'/etc/thermo/endeca/focusAreas/default.html', items: [ { "group": null, "id": "all-categories", "title": "Search All", "searchURL": "/search/results?query={keyword}&focusarea={focusAreaName}", "typeAheadURL": "/search/service/typeaheadSuggestions?query={keyword}", "include": null, "exclude": null, "activation": null }, { "group": null, "id": "trial-catalog", "title": "Aspire Free Products", "searchURL": "/store/aspire/trials/searchTerm/{keyword}", "typeAheadURL": "/search/loyalty/service/typeahead?keyword={keyword}", "include": null, "exclude": null, "activation": ".*\/store\/aspire\/trials.*|.*LoyaltyDashboardDisplay.*|.*\/store\/aspire.*|.*LoyaltyRewardsDisplay.*" }, { "group": "Popular Product Areas", "id": "taqman-assays", "title": "TaqMan Assays", "searchURL": "/order/genome-database/searchResults?productTypeSelect=taqman&keyword={keyword}", "typeAheadURL": "/order/genome-database/keywordTypeAhead?query={keyword}&wt=json&indent=on&version=2.2&start=0&rows=15&fl=value%2Ctype&qt=standard&filters=filter1%3A(\"TAQMAN\")", "include": null, "exclude": ".*persona.DocSupport.*", "activation": ".*\/genome-database\/.*productTypeSelect.taqman.keyword.*|.*\/genome-database\/.*taqman*" }, { "group": "Popular Product Areas", "id": "gene-exp-assays", "title": "Gene Expression", "searchURL": "/order/genome-database/?pearUXVerSuffix=pearUX2&elcanoForm=true#!/ge/assays/ge_all/?keyword={keyword}", "typeAheadURL": "/order/genome-database/keywordTypeAhead?query={keyword}&wt=json&indent=on&version=2.2&start=0&rows=15&fl=value%2Ctype&qt=standard&filters=filter1%3A(%22GE%22)", "include": ".*\/order\/genome.*|.*\/taqman-gene-expression\/product\/.*|.*\/taqman-gene-expression\/query\/.*", "exclude": ".*persona.DocSupport.*", "activation": ".*\/genome-database\/browse\/gene-expression\/.*|.*\/genome-database\/details\/gene-expression\/.*|.*\/genome-database\/.*ge_all.*|.*\/genome-database\/.*plate_all.*|.*\/taqman-gene-expression\/product\/.*|.*\/taqman-gene-expression\/query\/.*" }, { "group": "Popular Product Areas", "id": "microbe-abr-detection", "title": "Microbe & ABR Detection", "searchURL": "/order/genome-database/?pearUXVerSuffix=pearUX2&elcanoForm=true#!/taqman/?keyword={keyword}&productSearch=microbe", "typeAheadURL": "/order/genome-database/keywordTypeAhead?query={keyword}&wt=json&indent=on&version=2.2&start=0&rows=15&fl=value%2Ctype&qt=standard&filters=filter1%3A(%22MCRB%22)", "include": ".*\/order\/genome.*|.*\/microbe-detection\/taqman\/query\/.*|.*\/antibiotic-resistance\/taqman\/query\/.*|.*\/microbe-detection\/taqman\/target-list\/.*|.*\/home\/clinical\/clinical-genomics\/pathogen-detection-solutions.*", "exclude": ".*persona.DocSupport.*", "activation": null }, { "group": "Popular Product Areas", "id": "microbe-detection", "title": "Microbe Detection", "searchURL": "/microbe-detection/taqman/query/{keyword}", "typeAheadURL": "/order/genome-database/keywordTypeAhead?query={keyword}&wt=json&indent=on&version=2.2&start=0&rows=15&fl=value%2Ctype&qt=standard&filters=filter1%3A(%22MCRB%22)", "include": ".*\/microbe-detection\/taqman\/query\/.*", "exclude": ".*persona.DocSupport.*", "activation": ".*\/microbe-detection\/taqman\/query\/.*" }, { "group": "Popular Product Areas", "id": "antibiotic-resistance", "title": "Antibiotic Resistance", "searchURL": "/antibiotic-resistance/taqman/query/{keyword}", "typeAheadURL": "/order/genome-database/keywordTypeAhead?query={keyword}&wt=json&indent=on&version=2.2&start=0&rows=15&fl=value%2Ctype&qt=standard&filters=filter1%3A(%22MCRB%22)", "include": ".*\/antibiotic-resistance\/taqman\/query\/.*", "exclude": ".*persona.DocSupport.*", "activation": ".*\/antibiotic-resistance\/taqman\/query\/.*" }, { "group": "Popular Product Areas", "id": "crispr-guide-rna", "title": "CRISPR Guide RNA", "searchURL": "/crispr/invitrogen/query/{keyword}", "typeAheadURL": "/order/genome-database/keywordTypeAhead?query={keyword}&start=0&rows=15&fl=value%2Ctype&qt=standard&filters=filter1%3A(%22CRSPR%22)", "include": ".*\/crispr\/.*|.*\/geneart.crispr\/.*|.*\/genome.editing\/geneart.crispr\/crispr.libraries\/lentiarray.crispr.libraries\/lentiarray.grnas.*|.*\/genome.database\/browse\/trueguide\/.*|.*\/genome.database\/browse\/lentiviral.*|.*productTypeSelect.crspr.targetTypeSelect.crspr.lentiviral.*|.*productTypeSelect.crspr.targetTypeSelect.crspr.true.guide.sgrna.*", "exclude": ".*persona.DocSupport.*", "activation": ".*\/crispr\/.*|.*\/geneart.crispr\/.*|.*\/genome.editing\/geneart.crispr\/crispr.libraries\/lentiarray.crispr.libraries\/lentiarray.grnas.*|.*\/genome.editing\/geneart.crispr\/crispr.grna.*|.*\/genome.database\/browse\/trueguide\/.*|.*\/genome.database\/browse\/lentiviral.*|.*productTypeSelect.crspr.targetTypeSelect.crspr.lentiviral.*|.*productTypeSelect.crspr.targetTypeSelect.crspr.true.guide.sgrna.*" }, { "group": "Popular Product Areas", "id": "copy-number-variation", "title": "Copy Number Variation", "searchURL": "/order/genome-database/?pearUXVerSuffix=pearUX2&elcanoForm=true#!/cnv/assays/cnv_all/?keyword={keyword}", "typeAheadURL": "/order/genome-database/keywordTypeAhead?query={keyword}&wt=json&indent=on&version=2.2&start=0&rows=15&fl=value%2Ctype&qt=standard&filters=%E2%80%9C&filters=filter1%3A(%22CNV%22)%E2%80%9D", "include": ".*\/order\/genome.*|.*\/taqman-gene-expression\/product\/.*|.*\/taqman-gene-expression\/query\/.*", "exclude": ".*persona.DocSupport.*", "activation": ".*\/genome-database\/browse\/cnv\/.*|.*\/genome-database\/details\/cnv\/.*|.*\/genome-database\/.*cnv_all.*" }, { "group": "Popular Product Areas", "id": "mutation-detection", "title": "Mutation Detection", "searchURL": "/order/genome-database/?pearUXVerSuffix=pearUX2&elcanoForm=true#!/mutation/assays/mutation_castPCR/?keyword={keyword}", "typeAheadURL": "/order/genome-database/keywordTypeAhead?query={keyword}&wt=json&indent=on&version=2.2&start=0&rows=15&fl=value%2Ctype&qt=standard&filters=%E2%80%9C&filters=filter1%3A(%22CPCR%22)%E2%80%9D", "include": ".*\/order\/genome.*|.*\/taqman-gene-expression\/product\/.*|.*\/taqman-gene-expression\/query\/.*", "exclude": ".*persona.DocSupport.*", "activation": ".*\/genome-database\/browse\/mutation-detection\/.*|.*\/genome-database\/details\/DPCR\/.*|.*\/genome-database\/.*mutation_digitalPCR.*" }, { "group": "Popular Product Areas", "id": "mirna", "title": "miRNA", "searchURL": "/order/genome-database/?pearUXVerSuffix=pearUX2&elcanoForm=true#!/microrna/assays/microrna_mature/?keyword={keyword}", "typeAheadURL": "/order/genome-database/keywordTypeAhead?query={keyword}&wt=json&indent=on&version=2.2&start=0&rows=15&fl=value%2Ctype&qt=standard&filters=filters=filter1%3A(%22MIRNA%22)%E2%80%9D", "include": ".*\/order\/genome.*|.*\/taqman-gene-expression\/product\/.*|.*\/taqman-gene-expression\/query\/.*", "exclude": ".*persona.DocSupport.*", "activation": ".*\/genome-database\/.*microrna_mature.*|.*\/genome-database\/.*microrna_advanced.*|.*\/genome-database\/.*microrna_all.*" }, { "group": "Popular Product Areas", "id": "snp-genotyping", "title": "SNP Genotyping", "searchURL": "/order/genome-database/?pearUXVerSuffix=pearUX2&elcanoForm=true#!/genotyping/assays/genotyping_all/?keyword={keyword}", "typeAheadURL": "/order/genome-database/keywordTypeAhead?query={keyword}&wt=json&indent=on&version=2.2&start=0&rows=15&fl=value%2Ctype&qt=standard&filters=%E2%80%9C&filters=filter1%3A(%22GT%22)%E2%80%9D", "include": ".*\/order\/genome.*|.*\/taqman-gene-expression\/product\/.*|.*\/taqman-gene-expression\/query\/.*", "exclude": ".*persona.DocSupport.*", "activation": ".*\/genome-database\/browse\/genotyping\/.*|.*\/genome-database\/details\/genotyping\/.*|.*\/genome-database\/.*genotyping_all.*|.*\/genome-database\/.*productTypeSelect=genotyping.*" }, { "group": "Popular Product Areas", "id": "primary-antibodies", "title": "Primary Antibodies", "searchURL": "/antibody/primary/query/{keyword}", "typeAheadURL": "/order/genome-database/keywordTypeAhead?query={keyword}&wt=json&indent=on&version=2.2&start=0&rows=15&fl=value%2Ctype&qt=standard&filters=filter1%3A(%22PRANT%22)+AND+filter3%3A(%22Pri-Anti%22)", "include": null, "exclude": ".*persona.DocSupport.*", "activation": ".*\/home\/life-science\/antibodies.html|.*\/home\/life-science\/antibodies\/primary.*|.*\/home\/life-science\/antibodies\/invitrogen-antibody-validation.*|.*\/antibody\/primary.*|.*\/antibody\/product\/.*-.ntibody.*|.*\/home\/life-science\/cell-analysis\/flow-cytometry\/antibodies-for-flow-cytometry.*|.*\/home\/order\/antibodies-immunoassays.html|.*\/antibody\/sitemap\/Primary-Antibodies-.*|.*\/antibody\/target\/.*|.*\/antibody\/gene\/.*|.*\/home\/life-science\/protein-biology\/protein-assays-analysis\/western-blotting\/detect-proteins-western-blot\/western-blot-detection-reagents\/western-blot-antibodies.*|.*\/home\/life-science\/antibodies\/primary-antibodies\/control-antibodies\/loading-control-antibodies.*" }, { "group": "Popular Product Areas", "id": "secondary-antibodies", "title": "Secondary Antibodies", "searchURL": "/antibody/secondary/query/{keyword}", "typeAheadURL": null, "include": null, "exclude": ".*persona.DocSupport.*", "activation": ".*\/home\/life-science\/antibodies\/secondary.*|.*\/antibody\/secondary.*|.*\/antibody\/product\/.*-.econdary-.ntibody.*|.*\/antibody\/sitemap\/Secondary-Antibodies-.*" }, { "group": "Popular Product Areas", "id": "isotype-controls", "title": "Isotype Controls", "searchURL": "/antibody/control/query/{keyword}", "typeAheadURL": null, "include": ".*\/antibody\/.*|.*\/elisa\/product\/.*|\/order\/genome.*|.*-.ntibody.*|.*-.rotein.*|.*-.eptide.*|.*-.ontrol.*|.*\/home\/order\/antibodies-immunoassays.html|.*\/proteins\/.*|.*\/immunoassays\/.*|.*\/elisa\/product\/.*", "exclude": ".*persona.DocSupport.*", "activation": ".*\/home\/life-science\/antibodies\/primary-antibodies\/control-antibodies.*|.*\/antibody\/product\/.*-.ontrol\/.*|.*\/antibody\/control\/.*|.*\/antibody\/sitemap\/Control-Antibodies-.*" }, { "group": "Popular Product Areas", "id": "proteins-and-peptides", "title": "Proteins & Peptides", "searchURL": "/proteins/query/{keyword}", "typeAheadURL": "/order/genome-database/keywordTypeAhead?query={keyword}&wt=json&indent=on&version=2.2&start=0&rows=15&fl=value%2Ctype&qt=standard&filters=filter1%3A(%22PRANT%22)+AND+filter3%3A(%22Sec-Anti%22)", "include": ".*\/proteins\/.*|.*\/antibody\/.*|.*\/elisa\/product\/.*|.*\/order\/genome.*|.*-.ntibody.*|.*-.rotein.*|.*-.eptide.*|.*-.ontrol.*|.*\/home\/order\/antibodies-immunoassays.html|.*\/immunoassays\/.*|.*\/elisa\/product\/.*", "exclude": ".*persona.DocSupport.*", "activation": ".*\/proteins\/.*|.*\/query\/.*-.ecombinant-.rotein\/.*|.*\/proteins\/query\/.*-.ynthetic-.eptide\/.*|.*\/proteins\/query\/.*-.ative-.rotein\/.*" }, { "group": "Popular Product Areas", "id": "elisa-kits", "title": "ELISA Kits", "searchURL": "/immunoassays/elisa/query/{keyword}", "typeAheadURL": "/order/genome-database/typeAheadSearch?keyword={keyword}&productSubType=elisa", "include": null, "exclude": ".*persona.DocSupport.*", "activation": ".*\/home\/life-science\/antibodies\/immunoassays\/elisa-kits.*|.*\/elisa\/product\/.*|.*\/immunoassays\/elisa\/query\/.*|.*\/immunoassays\/elisa\/target\/.*|.*\/immunoassays\/target\/.*" }, { "group": null, "id": "all-documents-support", "title": "All Documents & Support", "searchURL": "/search/results?query={keyword}&persona=DocSupport", "typeAheadURL": "n/a", "include": null, "exclude": ".*persona.DocSupport.*", "activation": ".*\/search\/results.query.*persona.DocSupport.*" }, { "group": null, "id": "certificates", "title": "Certificates", "searchURL": "/search/results?query={keyword}&persona=DocSupport&refinementAction=true&filter=document.result_type_s%3ACertificates", "typeAheadURL": null, "include": null, "exclude": null, "activation": ".*4294837200.*|.*docTypes=COA.*|.*filter.document.result.type.*Certificates.*" }, { "group": null, "id": "sds", "title": "SDS", "searchURL": "/search/results?query={keyword}&persona=DocSupport&filter=document.result_type_s%3ASDS&refinementAction=true", "typeAheadURL": null, "include": null, "exclude": null, "activation": ".*4294837192.*|.*docTypes=SDS.*|.*filter.document.result.type.*SDS.*" }, { "group": null, "id": "manuals-and-protocols", "title": "Manuals & Protocols", "searchURL": "/search/results?query={keyword}&persona=DocSupport&refinementAction=true&filter=document.result_type_s%3AManuals%20%26%20Protocols", "typeAheadURL": null, "include": null, "exclude": null, "activation": ".*4294837203.*|.*docTypes.Manuals.*|.*filter.document.result.type.*Manuals.*Protocols.*" }, { "group": null, "id": "support-files", "title": "Support Files", "searchURL": "/search/results?query={keyword}&persona=DocSupport&refinementAction=true&filter=document.result_type_s%3ASupport%20Files", "typeAheadURL": null, "include": ".*persona.DocSupport.*", "exclude": null, "activation": ".*4294837196.*|.*docTypes.SupportFiles.*|.*filter.document.result.type.*Support.*Files.*" }, { "group": null, "id": "product-literature", "title": "Product Literature", "searchURL": "/search/results?query={keyword}&persona=DocSupport&refinementAction=true&filter=document.result_type_s%3AProduct%20Literature", "typeAheadURL": null, "include": ".*persona.DocSupport.*", "exclude": null, "activation": ".*4294837193.*|.*docTypes.Brochures.*|.*filter.document.result.type.*Product.*Literature.*" }, { "group": null, "id": "citations-and-references", "title": "Citations & References", "searchURL": "/search/results?query={keyword}&persona=DocSupport&refinementAction=true&filter=document.result_type_s%3ACitations%20%26%20References", "typeAheadURL": null, "include": ".*persona.DocSupport.*", "exclude": null, "activation": ".*4294845218.*|.*docTypes.Citations.*|.*filter.document.result.type.*Citations.*References.*" }, { "group": null, "id": "product-faqs", "title": "Product FAQs", "searchURL": "/search/results?query={keyword}&persona=DocSupport&refinementAction=true&filter=document.result_type_s%3AProduct%20FAQs", "typeAheadURL": null, "include": null, "exclude": null, "activation": ".*4294837268.*|.*docTypes.FAQ.*|.*filter.document.result.type.*Product.*FAQs.*" }, { "group": null, "id": "ordering-and-web-faqs", "title": "Ordering & Web FAQs", "searchURL": "/search/results?query={keyword}&persona=DocSupport&filter=document.result_type_s%3AOrdering%20%26%20Web%20FAQs&refinementAction=true", "typeAheadURL": null, "include": ".*persona.DocSupport.*", "exclude": null, "activation": ".*navId.4294837259.*|.*filter.document.result.type.*Ordering.*Web.*FAQs.*" }, { "group": null, "id": "media-formulations", "title": "Media Formulations", "searchURL": "/search/results?query={keyword}&persona=DocSupport&filter=document.result_type_s%3AMedia%20Formulations&refinementAction=true", "typeAheadURL": null, "include": ".*persona.DocSupport.*", "exclude": null, "activation": ".*4294837198.*|.*docTypes.MediaFormulation.*|.*filter.document.result.type.*Media.*Formulations.*" }, { "group": null, "id": "molecular-probes-handbook", "title": "Molecular Probes Handbook", "searchURL": "/search/results?query={keyword}&persona=DocSupport&refinementAction=true&filter=document.result_type_s%3AMolecular%20Probes%20Handbook", "typeAheadURL": null, "include": ".*persona.DocSupport.*", "exclude": null, "activation": ".*4294837201.*|.*docTypes.Probes.*Handbook.*|.*filter.document.result.type.*Molecular.*Probes.*Handbook.*" }, { "group": null, "id": "spectra-data", "title": "Spectra Data", "searchURL": "/search/results?query={keyword}&persona=DocSupport&filter=document.result_type_s%3ASpectra%20Data&refinementAction=true", "typeAheadURL": null, "include": ".*persona.DocSupport.*", "exclude": null, "activation": ".*4294837270.*|.*docTypes.Probes.*Spectra.*|.*filter.document.result.type.*Spectra.*Data.*" }, { "group": null, "id": "vector-data", "title": "Vector Data", "searchURL": "/search/results?query={keyword}&persona=DocSupport&refinementAction=true&filter=document.result_type_s%3AVector%20Data", "typeAheadURL": null, "include": ".*persona.DocSupport.*", "exclude": null, "activation": ".*4294837191.*|.*docTypes.Vectors.*|.*filter.document.result.type.*Vector.*Data.*" } ] }; </script> <div class="main-header-container">  <script type="text/javascript"> window.performance && window.performance.mark && window.performance.mark("header_6"); </script>  <div id="nav-container" class="nav-container pragma-toggle-component"> <span class="sr-only">Hamburger Menu Button</span> <div id="hamburger-btn" class="menu hamburger-btn pragma-toggle" data-toggle="#nav-container,#full-bg" data-toggle-classes="open" tabindex="0"> <span class="icon"></span> </div> <nav id="mega-nav" class="mega-nav"> <span class="close pragma-toggle" data-toggle="#nav-container,#full-bg" data-toggle-classes="open"></span>  <span class="logo"> <a rel="home" href="/sg/en/home.html" id="hfLifetechLogoLinkSideNav"> <svg id="Layer_1" data-name="Layer 1" aria-labelledby="logo-alt" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 485.52 223.55"> <title id="logo-alt">Thermo Fisher Scientific Logo</title> <defs> <style> .tf-logo-cls-1 { fill: #E71316; } .tf-logo-cls-2 { fill: #fff; } </style> </defs> <rect class="tf-logo-cls-1" width="485.52" height="223.55" /> <path class="tf-logo-cls-2" d="M108.27,83.11V76h-32v7.13h11v31h9.92v-31Zm123.5,31c-.26-2.53-.42-4.49-.42-5.81V95.46c0-5.33-3.91-8.65-9.08-8.65a10.21,10.21,0,0,0-8.82,4.69c-1.11-3-4.38-4.54-7.44-4.54-3.7,0-6.81,1.22-8.55,4.54l-.22-4h-9.07V114.1h9.39v-16c0-.84-.37-5.38,4-5.38,2.91,0,3.59,2.59,3.59,5.12V114.1h9.34v-16c0-.84-.37-5.38,4-5.38,2.91,0,3.6,2.59,3.6,5.12V114.1ZM186,95.35V87.28c-4.07,0-7.18,1.27-8.39,5.33l-.22-5.07H168c.21,2.17.21,5.07.21,6.82V114.1h9.4V102.48c0-4.38,1.26-7.07,6.44-7.17.63,0,1.26,0,1.95,0m62-8.54c-8.66,0-14.31,4.8-14.31,13.93,0,9.4,5.71,14.1,14.31,14.1s14.31-4.7,14.31-14.1c0-9.13-5.65-13.93-14.31-13.93m0,5.59c4,0,4.7,4.06,4.7,8.23,0,4.86-.85,8.66-4.7,8.66s-4.7-3.8-4.7-8.66c0-4.22.74-8.28,4.7-8.28ZM137.21,114.1a57.55,57.55,0,0,1-.37-5.81V95.46c0-5.33-4-8.65-9.13-8.65a11.12,11.12,0,0,0-4.44.84,9.58,9.58,0,0,0-3.38,2.69V76H110.5V114.1h9.39v-16c0-.84-.36-5.38,4-5.38,3,0,3.59,2.59,3.59,5.12V114.1Zm28.72-11.46c0-9.55-2.8-15.83-13.41-15.83-8.39,0-13.41,5.17-13.41,13.25,0,9.92,3.54,14.78,13.88,14.78a14.49,14.49,0,0,0,8.24-2.22,9.58,9.58,0,0,0,4.49-7.29h-8.87a4.15,4.15,0,0,1-4.49,4.07c-3.59,0-4.32-3.43-4.27-6.76Zm-9-5.12h-8.71c.21-2.8.84-5.65,4.32-5.8a3.49,3.49,0,0,1,3.33,1.84,7.36,7.36,0,0,1,1.06,4Z" /> <path class="tf-logo-cls-2" d="M409.29,94.88V86.81c-4.06-.06-7.18,1.26-8.39,5.33l-.21-4.6H391.3c.2,2.17.2,5.07.2,6.81v19.74h9.4V102.48c0-4.38,1.27-7.54,6.44-7.65.63,0,1.26,0,2,0m-48.87,19.21a54.56,54.56,0,0,1-.37-5.8V95.47c0-5.34-4-8.66-9.13-8.66a10.52,10.52,0,0,0-4.33.84,9.73,9.73,0,0,0-3.49,2.69V76h-9.39v38.11h9.39v-16c0-.84-.37-5.38,4-5.38,2.95,0,3.59,2.58,3.59,5.12v16.25Zm-29-7.91c0-4.12-2.16-6.12-5.17-7.23-5.65-2-9.88-2.11-9.88-4.23a2.24,2.24,0,0,1,2.44-2.48,3.34,3.34,0,0,1,2.52.85,3.7,3.7,0,0,1,.69,2.53h8.92c-.21-7-5.7-8.81-11.72-8.81-5.12,0-11.76,1.79-11.76,8.18,0,9.29,15,6.86,15,11.82,0,1.75-1.43,2.53-3.28,2.53a2.92,2.92,0,0,1-2.42-1.26,3.36,3.36,0,0,1-.58-2.59h-9c-.16,7.92,5.7,9.35,12.19,9.35,6.08,0,12-2.22,12-8.66m57.78-3.54c.06-9.55-2.79-15.83-13.41-15.83-8.39,0-13.41,5.17-13.41,13.25,0,9.92,3.54,14.78,13.89,14.78a14.56,14.56,0,0,0,8.23-2.22,9.52,9.52,0,0,0,4.49-7.29H380.1a4.14,4.14,0,0,1-4.48,4.07c-3.59,0-4.33-3.43-4.28-6.76Zm-9-5.12H371.5c.21-2.8.84-5.65,4.33-5.8a3.51,3.51,0,0,1,3.33,1.85,7.38,7.38,0,0,1,1,4Zm-75.39-10h-9.39V114.1h9.39ZM292.5,83l2.22-7H269.47v38.11h9.92v-15h8l2.21-7H279.39V83Zm12.32,0,2.23-7h-9.29l-2.22,7Z" /> <path class="tf-logo-cls-2" d="M162.45,125.26h3.44v21.61h-3.44Zm232,22c-7.21,0-12.59-4-12.59-11s6-11.42,12.81-11.42a13.4,13.4,0,0,1,6.78,1.9l-1.77,2.09a10.44,10.44,0,0,0-5-1.41,9,9,0,0,0-6.85,2.64,8.89,8.89,0,0,0-2.18,6.33,7.9,7.9,0,0,0,2.56,6.3c1.65,1.63,4.18,2.08,6.66,2.08a12.1,12.1,0,0,0,5.46-1.55l1.68,2a14.64,14.64,0,0,1-7.59,2m-36.24-22h3.44v21.61h-3.44Zm-77.92,2.58h-8.05v19h-3.36v-19h-8v-2.58h19.77ZM100.78,146.1a13.66,13.66,0,0,1-6.09,1.22A20.13,20.13,0,0,1,86,145.37l1.43-2.45a16.3,16.3,0,0,0,7.54,1.82,7.65,7.65,0,0,0,3.93-.88,3.14,3.14,0,0,0,1.9-2.79c0-1.81-1.39-2.93-4.73-3.71l-3.51-.82c-3.5-.82-5.7-3-5.7-5.56,0-3.68,3.62-6.29,8.78-6.29a16.39,16.39,0,0,1,8.29,2.06L102.33,129a13.46,13.46,0,0,0-6.55-1.73c-3.07,0-5.2,1.19-5.2,3.22,0,1.56,1.3,2.49,4.31,3.22l3.25.78a11.33,11.33,0,0,1,4.78,2.18,5.38,5.38,0,0,1,1.68,3.86,6.4,6.4,0,0,1-3.82,5.57m138.41.77-8.58-11.52c-1.61-2.16-4.33-6.38-4.33-6.38s.3,3.65.32,6.85l.09,11.05h-3.43V125.26h4.09L236,137c1.69,2.29,4,5.92,4,5.92s-.52-4-.54-6.84l-.08-10.85h3.4v21.61Zm59.2-21.61h3.45v21.61h-3.45Zm41,2.54H327.56v6.4h10v2.54h-10v10.13h-3.45V125.26h15.76ZM188.17,146.87V125.26H204.1l-.46,2.58h-12v6.44h10.24v2.58h-10.2v7.3h12.86v2.71Zm-52.36.37c-7.2,0-12.58-4-12.58-11s6-11.42,12.8-11.42a13.4,13.4,0,0,1,6.78,1.9l-1.76,2.09a10.44,10.44,0,0,0-5-1.41,9,9,0,0,0-6.86,2.64,8.89,8.89,0,0,0-2.18,6.33,7.9,7.9,0,0,0,2.57,6.3c1.65,1.63,4.17,2.08,6.65,2.08a12.1,12.1,0,0,0,5.46-1.55l1.68,2a14.59,14.59,0,0,1-7.59,2" /> </svg> </a> </span> <div class="account-dd"> <div class="account"> <div class="cmp-p-ctaitem m--btn-primary m--block"> <div class="cmp-ctaitem"> <a class="cmp-ctaitem__anchor" href="/auth/initiate"> <span class="cmp-ctaitem__text">Sign in</span> </a> </div> </div> <div class="create-account pt-l1 pb-l1 border-bottom">Don't have an account ? <a href="/auth/create-account">Create Account</a> </div> <div class="create-account"> </div> </div> </div> <ul id='primary-nav' class='main-nav' data-analytics-section='top'> <li id='primary-link-1' class='main-nav-item pragma-toggle' data-toggle='#primary-link-1,nav' data-toggle-classes='open' data-analytics-section='top' data-analytics-parent='Products' tabindex='0'> <span class='arrow'></span>Products <ul id='secondary-nav-1' class='sub-nav'> <li id='secondary-link-1-1' > <a href='/sg/en/home/life-science/antibodies.html' data-analytics-section='top' data-analytics-parent='Products' data-analytics-text='Antibodies'> Antibodies </a> </li> <li id='secondary-link-1-2' > <a href='/search/browse/category/us/en/90217060' data-analytics-section='top' data-analytics-parent='Products' data-analytics-text='Cell Culture Media'> Cell Culture Media </a> </li> <li id='secondary-link-1-3' > <a href='/sg/en/home/chemicals.html' data-analytics-section='top' data-analytics-parent='Products' data-analytics-text='Chemicals'> Chemicals </a> </li> <li id='secondary-link-1-4' > <a href='/search/browse/category/us/en/90155038' data-analytics-section='top' data-analytics-parent='Products' data-analytics-text='Western Blot Products'> Western Blot Products </a> </li> <li id='secondary-link-1-5' > <a href='/search/browse/category/us/en/90126197' data-analytics-section='top' data-analytics-parent='Products' data-analytics-text='Chromatography Columns and Cartridges'> Chromatography Columns and Cartridges </a> </li> <li id='secondary-link-1-6' > <a href='/sg/en/home/life-science/lab-equipment.html' data-analytics-section='top' data-analytics-parent='Products' data-analytics-text='Lab Equipment'> Lab Equipment </a> </li> <li id='secondary-link-1-7' > <a href='/sg/en/home/life-science/lab-plasticware-supplies.html' data-analytics-section='top' data-analytics-parent='Products' data-analytics-text='Lab Plasticware and Supplies'> Lab Plasticware and Supplies </a> </li> <li id='secondary-link-1-8' > <a href='/search/browse/category/us/en/90111007' data-analytics-section='top' data-analytics-parent='Products' data-analytics-text='Microplates'> Microplates </a> </li> <li id='secondary-link-1-9' > <a href='/sg/en/home/life-science/oligonucleotides-primers-probes-genes.html' data-analytics-section='top' data-analytics-parent='Products' data-analytics-text='Oligos, Primers, Probes and Genes'> Oligos, Primers, Probes and Genes </a> </li> <li id='secondary-link-1-10' > <a href='/sg/en/home/life-science/pcr/real-time-pcr/real-time-pcr-assays.html' data-analytics-section='top' data-analytics-parent='Products' data-analytics-text='TaqMan Real-Time PCR Assays'> TaqMan Real-Time PCR Assays </a> </li> <li id='secondary-link-1-11' > <a href='/sg/en/home/sustainable-design' data-analytics-section='top' data-analytics-parent='Products' data-analytics-text='Greener Products'> Greener Products </a> </li> <li> <span class='see-all'> <a href='/sg/en/home/order.html' data-analytics-section='top' data-analytics-parent='Products' data-analytics-text='See all product categories'> See all product categories <span class='right-arrow'></span> </a> </span> </li> </ul> </li> <li id='primary-link-2' class='main-nav-item pragma-toggle' data-toggle='#primary-link-2,nav' data-toggle-classes='open' data-analytics-section='top' data-analytics-parent='Applications' tabindex='0'> <span class='arrow'></span>Applications <ul id='secondary-nav-2' class='sub-nav'> <li id='secondary-link-2-1' > <a href='/sg/en/home/life-science/bioproduction.html' data-analytics-section='top' data-analytics-parent='Applications' data-analytics-text='Bioprocessing'> Bioprocessing </a> </li> <li id='secondary-link-2-2' > <a href='/sg/en/home/life-science/cell-culture.html' data-analytics-section='top' data-analytics-parent='Applications' data-analytics-text='Cell Culture and Transfection'> Cell Culture and Transfection </a> </li> <li id='secondary-link-2-3' > <a href='/content/lifetech/global/en/home/industrial/food-beverage.html' data-analytics-section='top' data-analytics-parent='Applications' data-analytics-text='Food and Beverage'> Food and Beverage </a> </li> <li id='secondary-link-2-4' > <a href='/content/lifetech/global/en/home/lab-solutions.html' data-analytics-section='top' data-analytics-parent='Applications' data-analytics-text='Lab Solutions'> Lab Solutions </a> </li> <li id='secondary-link-2-5' > <a href='/content/lifetech/global/en/home/industrial/pharma-biopharma.html' data-analytics-section='top' data-analytics-parent='Applications' data-analytics-text='Pharma and Biopharma'> Pharma and Biopharma </a> </li> <li id='secondary-link-2-6' > <a href='/content/lifetech/global/en/home/life-science/pcr/real-time-pcr.html' data-analytics-section='top' data-analytics-parent='Applications' data-analytics-text='Real-Time PCR'> Real-Time PCR </a> </li> <li id='secondary-link-2-7' > <a href='/sg/en/home/semiconductors.html' data-analytics-section='top' data-analytics-parent='Applications' data-analytics-text='Semiconductor Analysis'> Semiconductor Analysis </a> </li> <li id='secondary-link-2-8' > <a href='/content/lifetech/global/en/home/clinical.html' data-analytics-section='top' data-analytics-parent='Applications' data-analytics-text='Clinical and Diagnostics'> Clinical and Diagnostics </a> </li> <li id='secondary-link-2-9' > <a href='/sg/en/home/digital-solutions.html' data-analytics-section='top' data-analytics-parent='Applications' data-analytics-text='Digital Solutions'> Digital Solutions </a> </li> <li id='secondary-link-2-10' > <a href='/sg/en/home/industrial/spectroscopy-elemental-isotope-analysis.html' data-analytics-section='top' data-analytics-parent='Applications' data-analytics-text='Spectroscopy, Elemental and Isotope Analysis'> Spectroscopy, Elemental and Isotope Analysis </a> </li> <li> <span class='see-all'> <a href='/sg/en/home/applications-techniques.html' data-analytics-section='top' data-analytics-parent='Applications' data-analytics-text='See all applications and techniques'> See all applications and techniques <span class='right-arrow'></span> </a> </span> </li> </ul> </li> <li id='primary-link-3' class='main-nav-item pragma-toggle' data-toggle='#primary-link-3,nav' data-toggle-classes='open' data-analytics-section='top' data-analytics-parent='Services' tabindex='0'> <span class='arrow'></span>Services <ul id='secondary-nav-3' class='sub-nav'> <li id='secondary-link-3-1' > <a href='/sg/en/home/products-and-services/services/crdmo.html' data-analytics-section='top' data-analytics-parent='Services' data-analytics-text='Integrated CDMO-CRO Services'> Integrated CDMO-CRO Services </a> </li> <li id='secondary-link-3-2' > <a href='/sg/en/home/brands/patheon.html' data-analytics-section='top' data-analytics-parent='Services' data-analytics-text='CDMO Services'> CDMO Services </a> </li> <li id='secondary-link-3-3' > <a href='https://www.ppd.com/' data-analytics-section='top' data-analytics-parent='Services' data-analytics-text='CRO Services'> CRO Services </a> </li> <li id='secondary-link-3-4' > <a href='/sg/en/home/products-and-services/services/custom-services.html' data-analytics-section='top' data-analytics-parent='Services' data-analytics-text='Custom Services'> Custom Services </a> </li> <li id='secondary-link-3-5' > <a href='/sg/en/home/products-and-services/services/enterprise-services.html' data-analytics-section='top' data-analytics-parent='Services' data-analytics-text='Enterprise Services'> Enterprise Services </a> </li> <li id='secondary-link-3-6' > <a href='/sg/en/home/products-and-services/services/financial-leasing-services.html' data-analytics-section='top' data-analytics-parent='Services' data-analytics-text='Financial and Leasing Services'> Financial and Leasing Services </a> </li> <li id='secondary-link-3-7' > <a href='/sg/en/home/products-and-services/services/instrument-qualification-services.html' data-analytics-section='top' data-analytics-parent='Services' data-analytics-text='Instrument Services'> Instrument Services </a> </li> <li id='secondary-link-3-8' > <a href='/sg/en/home/digital-solutions/lab-informatics.html' data-analytics-section='top' data-analytics-parent='Services' data-analytics-text='Lab Informatics'> Lab Informatics </a> </li> <li id='secondary-link-3-9' > <a href='/sg/en/home/about-us/partnering-licensing/oem-commercial-supply.html' data-analytics-section='top' data-analytics-parent='Services' data-analytics-text='OEM and Commercial Supply'> OEM and Commercial Supply </a> </li> <li id='secondary-link-3-10' > <a href='/sg/en/home/products-and-services/services/training-services.html' data-analytics-section='top' data-analytics-parent='Services' data-analytics-text='Training Services'> Training Services </a> </li> <li> <span class='see-all'> <a href='/sg/en/home/products-and-services/services.html' data-analytics-section='top' data-analytics-parent='Services' data-analytics-text='See all services'> See all services <span class='right-arrow'></span> </a> </span> </li> </ul> </li> <li id='primary-link-4' class='main-nav-item pragma-toggle' data-toggle='#primary-link-4,nav' data-toggle-classes='open' data-analytics-section='top' data-analytics-parent='Help and Support' tabindex='0'> <span class='arrow'></span>Help and Support <ul id='secondary-nav-4' class='sub-nav'> <li id='secondary-link-4-1' > <a href='/sg/en/home/support/how-to-register-for-account.html' data-analytics-section='top' data-analytics-parent='Help and Support' data-analytics-text='Order Help'> Order Help </a> </li> <li id='secondary-link-4-2' > <a href='/sg/en/home/digital-solutions.html' data-analytics-section='top' data-analytics-parent='Help and Support' data-analytics-text='Digital Solutions'> Digital Solutions </a> </li> <li id='secondary-link-4-3' > <a href='/sg/en/home/technical-resources/instrument-support.html' data-analytics-section='top' data-analytics-parent='Help and Support' data-analytics-text='Product Support'> Product Support </a> </li> <li id='secondary-link-4-4' > <a href='/sg/en/home/technical-resources/technical-reference-library.html' data-analytics-section='top' data-analytics-parent='Help and Support' data-analytics-text='Technical Information'> Technical Information </a> </li> <li id='secondary-link-4-5' > <a href='/sg/en/home/technical-resources/learning-centers.html' data-analytics-section='top' data-analytics-parent='Help and Support' data-analytics-text='Training and Education'> Training and Education </a> </li> <li> <span class='see-all'> <a href='/sg/en/home/support.html' data-analytics-section='top' data-analytics-parent='Help and Support' data-analytics-text='See all help and support topics'> See all help and support topics <span class='right-arrow'></span> </a> </span> </li> </ul> </li> <li id='primary-link-5' class='main-nav-item pragma-toggle' data-toggle='#primary-link-5,nav' data-toggle-classes='open' data-analytics-section='top' data-analytics-parent='Popular' tabindex='0'> <span class='arrow'></span>Popular <ul id='secondary-nav-5' class='sub-nav'> <li id='secondary-link-5-1' class='popular' > <a href='/sg/en/home/life-science/pcr/real-time-pcr/real-time-pcr-assays.html' data-analytics-section='top' data-analytics-parent='Popular' data-analytics-text='TaqMan Real-Time PCR Assays'> <div> <img src='/content/dam/LifeTech/global/home-page/2019/taqman-hr-meganav.jpg' class='popular-image' loading='lazy' alt='TaqMan Real-Time PCR Assays'/> </div> <div class='pl-12'>TaqMan Real-Time PCR Assays</div> </a> </li> <li id='secondary-link-5-2' class='popular' > <a href='/sg/en/home/life-science/antibodies.html' data-analytics-section='top' data-analytics-parent='Popular' data-analytics-text='Antibodies'> <div> <img src='/content/dam/LifeTech/global/promotions/meganav/2017/01-Jan/popular2-175x115.gif' class='popular-image' loading='lazy' alt='Antibodies'/> </div> <div class='pl-12'>Antibodies</div> </a> </li> <li id='secondary-link-5-3' class='popular' > <a href='/sg/en/home/life-science/oligonucleotides-primers-probes-genes' data-analytics-section='top' data-analytics-parent='Popular' data-analytics-text='Oligos, Primers & Probes'> <div> <img src='/content/dam/LifeTech/global/home-page/images/oligos-main-popular.jpg' class='popular-image' loading='lazy' alt='Oligos, Primers & Probes'/> </div> <div class='pl-12'>Oligos, Primers & Probes</div> </a> </li> <li id='secondary-link-5-4' class='popular' > <a href='/sg/en/home/life-science/cloning/gene-synthesis/geneart-gene-synthesis.html' data-analytics-section='top' data-analytics-parent='Popular' data-analytics-text='GeneArt Gene Synthesis'> <div> <img src='/content/dam/LifeTech/global/promotions/meganav/2017/01-Jan/popular4-175x115.jpg' class='popular-image' loading='lazy' alt='GeneArt Gene Synthesis'/> </div> <div class='pl-12'>GeneArt Gene Synthesis</div> </a> </li> <li id='secondary-link-5-5' class='popular' > <a href='/sg/en/home/life-science/cell-culture/cell-culture-plastics.html' data-analytics-section='top' data-analytics-parent='Popular' data-analytics-text='Cell Culture Plastics'> <div> <img src='/content/dam/LifeTech/global/promotions/meganav/2017/01-Jan/popular5-175x115.jpg' class='popular-image' loading='lazy' alt='Cell Culture Plastics'/> </div> <div class='pl-12'>Cell Culture Plastics</div> </a> </li> </ul> </li> </ul> <ul class='support'> <li id='support-links-1'> <a href='/sg/en/home/technical-resources/contact-us.html' data-analytics-section='top' data-analytics-parent='mega-nav' data-analytics-text='Contact Us'>Contact Us</a> </li> <li id='support-links-2'> <a href='/store/v2/quick-order' data-analytics-section='top' data-analytics-parent='mega-nav' data-analytics-text='Quick Order'>Quick Order</a> </li> <li id='support-links-3'> <a href='/store/orders/solu' data-analytics-section='top' data-analytics-parent='mega-nav' data-analytics-text='Order Status and Tracking'>Order Status and Tracking</a> </li> <li id='support-links-4'> <a href='/sg/en/home/support/documents-certificates.html' data-analytics-section='top' data-analytics-parent='mega-nav' data-analytics-text='Documents and Certificates'>Documents and Certificates</a> </li> </ul>  </nav>  <span class="logo"> <a rel="home" href="/sg/en/home.html" id="hfLifetechLogoLink"> <svg id="Layer_1" data-name="Layer 1" aria-labelledby="logo-alt" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 485.52 223.55"> <title id="logo-alt">Thermo Fisher Scientific Logo</title> <defs> <style> .tf-logo-cls-1 { fill: #E71316; } .tf-logo-cls-2 { fill: #fff; } </style> </defs> <rect class="tf-logo-cls-1" width="485.52" height="223.55" /> <path class="tf-logo-cls-2" d="M108.27,83.11V76h-32v7.13h11v31h9.92v-31Zm123.5,31c-.26-2.53-.42-4.49-.42-5.81V95.46c0-5.33-3.91-8.65-9.08-8.65a10.21,10.21,0,0,0-8.82,4.69c-1.11-3-4.38-4.54-7.44-4.54-3.7,0-6.81,1.22-8.55,4.54l-.22-4h-9.07V114.1h9.39v-16c0-.84-.37-5.38,4-5.38,2.91,0,3.59,2.59,3.59,5.12V114.1h9.34v-16c0-.84-.37-5.38,4-5.38,2.91,0,3.6,2.59,3.6,5.12V114.1ZM186,95.35V87.28c-4.07,0-7.18,1.27-8.39,5.33l-.22-5.07H168c.21,2.17.21,5.07.21,6.82V114.1h9.4V102.48c0-4.38,1.26-7.07,6.44-7.17.63,0,1.26,0,1.95,0m62-8.54c-8.66,0-14.31,4.8-14.31,13.93,0,9.4,5.71,14.1,14.31,14.1s14.31-4.7,14.31-14.1c0-9.13-5.65-13.93-14.31-13.93m0,5.59c4,0,4.7,4.06,4.7,8.23,0,4.86-.85,8.66-4.7,8.66s-4.7-3.8-4.7-8.66c0-4.22.74-8.28,4.7-8.28ZM137.21,114.1a57.55,57.55,0,0,1-.37-5.81V95.46c0-5.33-4-8.65-9.13-8.65a11.12,11.12,0,0,0-4.44.84,9.58,9.58,0,0,0-3.38,2.69V76H110.5V114.1h9.39v-16c0-.84-.36-5.38,4-5.38,3,0,3.59,2.59,3.59,5.12V114.1Zm28.72-11.46c0-9.55-2.8-15.83-13.41-15.83-8.39,0-13.41,5.17-13.41,13.25,0,9.92,3.54,14.78,13.88,14.78a14.49,14.49,0,0,0,8.24-2.22,9.58,9.58,0,0,0,4.49-7.29h-8.87a4.15,4.15,0,0,1-4.49,4.07c-3.59,0-4.32-3.43-4.27-6.76Zm-9-5.12h-8.71c.21-2.8.84-5.65,4.32-5.8a3.49,3.49,0,0,1,3.33,1.84,7.36,7.36,0,0,1,1.06,4Z" /> <path class="tf-logo-cls-2" d="M409.29,94.88V86.81c-4.06-.06-7.18,1.26-8.39,5.33l-.21-4.6H391.3c.2,2.17.2,5.07.2,6.81v19.74h9.4V102.48c0-4.38,1.27-7.54,6.44-7.65.63,0,1.26,0,2,0m-48.87,19.21a54.56,54.56,0,0,1-.37-5.8V95.47c0-5.34-4-8.66-9.13-8.66a10.52,10.52,0,0,0-4.33.84,9.73,9.73,0,0,0-3.49,2.69V76h-9.39v38.11h9.39v-16c0-.84-.37-5.38,4-5.38,2.95,0,3.59,2.58,3.59,5.12v16.25Zm-29-7.91c0-4.12-2.16-6.12-5.17-7.23-5.65-2-9.88-2.11-9.88-4.23a2.24,2.24,0,0,1,2.44-2.48,3.34,3.34,0,0,1,2.52.85,3.7,3.7,0,0,1,.69,2.53h8.92c-.21-7-5.7-8.81-11.72-8.81-5.12,0-11.76,1.79-11.76,8.18,0,9.29,15,6.86,15,11.82,0,1.75-1.43,2.53-3.28,2.53a2.92,2.92,0,0,1-2.42-1.26,3.36,3.36,0,0,1-.58-2.59h-9c-.16,7.92,5.7,9.35,12.19,9.35,6.08,0,12-2.22,12-8.66m57.78-3.54c.06-9.55-2.79-15.83-13.41-15.83-8.39,0-13.41,5.17-13.41,13.25,0,9.92,3.54,14.78,13.89,14.78a14.56,14.56,0,0,0,8.23-2.22,9.52,9.52,0,0,0,4.49-7.29H380.1a4.14,4.14,0,0,1-4.48,4.07c-3.59,0-4.33-3.43-4.28-6.76Zm-9-5.12H371.5c.21-2.8.84-5.65,4.33-5.8a3.51,3.51,0,0,1,3.33,1.85,7.38,7.38,0,0,1,1,4Zm-75.39-10h-9.39V114.1h9.39ZM292.5,83l2.22-7H269.47v38.11h9.92v-15h8l2.21-7H279.39V83Zm12.32,0,2.23-7h-9.29l-2.22,7Z" /> <path class="tf-logo-cls-2" d="M162.45,125.26h3.44v21.61h-3.44Zm232,22c-7.21,0-12.59-4-12.59-11s6-11.42,12.81-11.42a13.4,13.4,0,0,1,6.78,1.9l-1.77,2.09a10.44,10.44,0,0,0-5-1.41,9,9,0,0,0-6.85,2.64,8.89,8.89,0,0,0-2.18,6.33,7.9,7.9,0,0,0,2.56,6.3c1.65,1.63,4.18,2.08,6.66,2.08a12.1,12.1,0,0,0,5.46-1.55l1.68,2a14.64,14.64,0,0,1-7.59,2m-36.24-22h3.44v21.61h-3.44Zm-77.92,2.58h-8.05v19h-3.36v-19h-8v-2.58h19.77ZM100.78,146.1a13.66,13.66,0,0,1-6.09,1.22A20.13,20.13,0,0,1,86,145.37l1.43-2.45a16.3,16.3,0,0,0,7.54,1.82,7.65,7.65,0,0,0,3.93-.88,3.14,3.14,0,0,0,1.9-2.79c0-1.81-1.39-2.93-4.73-3.71l-3.51-.82c-3.5-.82-5.7-3-5.7-5.56,0-3.68,3.62-6.29,8.78-6.29a16.39,16.39,0,0,1,8.29,2.06L102.33,129a13.46,13.46,0,0,0-6.55-1.73c-3.07,0-5.2,1.19-5.2,3.22,0,1.56,1.3,2.49,4.31,3.22l3.25.78a11.33,11.33,0,0,1,4.78,2.18,5.38,5.38,0,0,1,1.68,3.86,6.4,6.4,0,0,1-3.82,5.57m138.41.77-8.58-11.52c-1.61-2.16-4.33-6.38-4.33-6.38s.3,3.65.32,6.85l.09,11.05h-3.43V125.26h4.09L236,137c1.69,2.29,4,5.92,4,5.92s-.52-4-.54-6.84l-.08-10.85h3.4v21.61Zm59.2-21.61h3.45v21.61h-3.45Zm41,2.54H327.56v6.4h10v2.54h-10v10.13h-3.45V125.26h15.76ZM188.17,146.87V125.26H204.1l-.46,2.58h-12v6.44h10.24v2.58h-10.2v7.3h12.86v2.71Zm-52.36.37c-7.2,0-12.58-4-12.58-11s6-11.42,12.8-11.42a13.4,13.4,0,0,1,6.78,1.9l-1.76,2.09a10.44,10.44,0,0,0-5-1.41,9,9,0,0,0-6.86,2.64,8.89,8.89,0,0,0-2.18,6.33,7.9,7.9,0,0,0,2.57,6.3c1.65,1.63,4.17,2.08,6.65,2.08a12.1,12.1,0,0,0,5.46-1.55l1.68,2a14.59,14.59,0,0,1-7.59,2" /> </svg> </a> </span> </div>  <script type="text/javascript"> window.performance && window.performance.mark && window.performance.mark("header_7"); </script> <div class="search-container"> <div class="search-layout">  <script type="text/javascript"> window.performance && window.performance.mark && window.performance.mark("header_8"); </script> <script src="/search/static/resources/js/signals.min.js" async></script> <script> var translations = {}; if ("prod" === "qa1" || "prod" === "qa4") { useV2Script = true; if (getCookie('enableSsi') === 'false') { useV2Script = false; } } else { useV2Script = "true" === "true"; if (getCookie('enableSsi') === 'false') { useV2Script = false; } else if (getCookie('enableSsi') === 'true') { useV2Script = true; } } var host = ''; if ("false" === true || "false" === 'true') { host = "//www.thermofisher.com"; } var searchEndpoint = '' if (useV2Script) { searchEndpoint = host + "/search/searchbar/resources/js/searchbarv2.js"; } else { searchEndpoint = host + "/search/searchbar/resources/js/searchbar.min.js"; } var script = document.createElement('script'); script.setAttribute('src', searchEndpoint); script.setAttribute('async', ''); var searchLayout = document.getElementsByClassName('search-layout'); if (searchLayout.length > 0) { searchLayout[0].appendChild(script); } else { document.body.appendChild(script); } </script> <script> var translations = { search: "Search by catalog number, product name, keyword, application", searchAll: "Search All", searchButton: "Search", searchIn: "Search within ", recentSearch: "Recent searches", moreWaysToSearch: "More ways to search", }; </script> <div class="search"> <div class="largeSearchBar" id="search-main"> <div class="searchHeading"> <p>Search <span>Thermo Fisher Scientific</span> </p> </div> <div id="searchModalBody" class="header_row_2 layout_cont_wrapper"> <div class="header_row_2 layout_cont_left" tabindex="0"> <div id="focusAreaSelector"> <div class="chosen-container chosen-container-single chosen-container-single-nosearch" style="width: 100%;" title="" id="chosenselector_chosen"><a class="chosen-single" tabindex="-1"><span>Search All </span> <div><b></b></div> </a></div> </div> </div> <div class="header_row_2 layout_cont_right"> </div> <div class="header_row_2 layout_cont_middle"> <div id="generalSearch" class="general_search layout_cont_wrapper"> <form id="smartsearch" method="get" autocomplete="off"> <input type="hidden" value="1" name="resultPage"> <input type="hidden" value="15" name="resultsPerPage"> <div class="general_search layout_cont_left"> </div> <div class="general_search layout_cont_right"> <button id="searchButton" type="submit" class="search-button" formaction="/search/results" tabindex="-1"> <p class="search-text">Search</p> <svg class="search-btn-icon" role="img" version="1.1" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink" xml:space="preserve"><defs><style>.cls-1-white{fill:#FFFFFF;}</style></defs><title>Search button</title><g id="Layer_462" data-name="Layer 462"><path class="cls-1-white" d="M27.49,26.45l-6.34-6.34a9.71,9.71,0,0,0-.31-13.42,9.76,9.76,0,0,0-13.77,0A9.73,9.73,0,0,0,19.66,21.45l6.41,6.42ZM8.48,19A7.73,7.73,0,1,1,14,21.31,7.68,7.68,0,0,1,8.48,19Z"/></g></svg> </button> </div> <div class="general_search layout_cont_middle"> <div id="generalSearchInput"> <div id="header-typeahead-input-container"> <input type="text" class="data-hj-whitelist" id="suggest1" name="query" accesskey="s" value="" role="search" autocomplete="off" placeholder="Search by catalog number, product name, keyword, application" tabindex="0"> <input type="text" id="header-typeahead-suggested" autocomplete="off" /> </div> <i id="searchMagnifyMobile" class="searchMagnifyMobile"> <svg class="search-btn-icon" role="img" version="1.1" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink" xml:space="preserve"><defs><style>.cls-1-grey{fill:#70707A;}</style></defs><title>Search button</title><g id="Layer_462" data-name="Layer 462"><path class="cls-1-grey" d="M27.49,26.45l-6.34-6.34a9.71,9.71,0,0,0-.31-13.42,9.76,9.76,0,0,0-13.77,0A9.73,9.73,0,0,0,19.66,21.45l6.41,6.42ZM8.48,19A7.73,7.73,0,1,1,14,21.31,7.68,7.68,0,0,1,8.48,19Z"/></g></svg> </i> <i id="searchRemove" class="clearable searchRemoveHide"> <svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 28 18"><defs><style>.cls-1-grey{fill:#54545C;}</style></defs><title>Close</title><g id="Layer_154" data-name="Layer 154"><path class="cls-1-grey" d="M9.40199 0L0.148438 8.82L9.40199 17.64H27.8147V0H9.40199ZM25.7164 15.64H10.2623L3.10706 8.82L10.2623 2H25.7164V15.64ZM12.0773 12.09L15.5081 8.82L12.0773 5.63L13.5567 4.22L16.9454 7.45L20.3342 4.22L21.824 5.63L18.4772 8.82L21.866 12.05L20.3762 13.47L16.9874 10.24L13.5986 13.47L12.0773 12.09Z"/></g></svg> </i> <div id="header-typeahead"> <input type="hidden" id="typeahead-autocomplete" name="autocomplete" /> <div> <ul class="flyout-recent-searches hide"></ul> </div> <div class="flyout-typeahead"> <div class="typeahead-terms"><ul class="typeahead-term-list"></ul></div> <div class="flyout-search-shortcut_right"> <ul class="search-shortcut-list"></ul> </div> </div> <div class="flyout-search-shortcut"> <ul class="search-shortcut-list"></ul> </div> </div> </div> </div> </form> </div> <span class="loading-wheel-sm hidden"></span> <div id="primarySearch"> </div> </div> <div class="clear"></div> </div> </div> <div class="global-commerce-bar-spacing"></div> </div> <input type="hidden" id="clientTranslations" value='{"search":"Search by catalog number, product name, keyword, application","searchAll":"Search All","searchButton":"Search","searchIn":"Search within ","recentSearch":"Recent searches","moreWaysToSearch":"More ways to search"}'/>  <script data-inline-file-name='searchbar.min.js' data-inline-site='tf'>/* Hash: 468bd07150dbbf Source: /tf/js/dist/searchbar.min.js */ window.searchbar={init:function(){performance.mark("enter_initSearchbar()");try{console.log("searchbar_init - attempting to initialize globalProviderConfig...");var e=window.globalProviderConfig;console.log("searchbar_init - globalProviderConfig: {\n\t focusAreaPath: "+e.focusAreaPath+",\n\t countryCode: "+e.countryCode+",\n\t langCode: "+e.langCode+",\n\t items: "+e.items.length+"\n}")}catch(e){console.error("ERROR: searchbar_init ",e)}try{console.info("searchbar_init - attempting to load translations..."),translations=JSON.parse(document.getElementById("clientTranslations").value),console.info("searchbar_init - translations load complete!")}catch(e){console.error("ERROR: searchbar_init ",e)}try{console.info("searchbar_init - attempting to load searchSelector..."),thermofisher.search.searchSelector.init(),console.info("searchbar_init - searchSelector load complete!")}catch(e){console.error("ERROR: searchbar_init ",e)}if(!1===useV2Script)try{console.info("searchbar_init - attempting to load searchFocusArea..."),thermofisher.search.searchFocusArea.init(),console.info("searchbar_init - searchFocusArea load complete!")}catch(e){console.error("ERROR: searchbar_init ",e)}try{console.info("searchbar_init - attempting to load searchProvider..."),thermofisher.search.searchProvider.init(),console.info("searchbar_init - searchProvider load complete!")}catch(e){console.error("ERROR: searchbar_init ",e)}try{console.info("searchbar_init - attempting to load SignalsStatic..."),thermofisher.search.SignalsStatic.init(),console.info("searchbar_init - SignalsStatic load complete!")}catch(e){console.error("ERROR: searchbar_init ",e)}console.info("searchbar_init - all loading complete!"),performance.mark("exit_initSearchbar()"),performance.mark("exit_initSearchBarAfterEvent()"),performance.measure("searchbar_init__initSearchBarAfterEvent()","enter_initSearchBarAfterEvent()","exit_initSearchBarAfterEvent()"),performance.measure("searchbar_init__initSearchbar()","enter_initSearchbar()","exit_initSearchbar()")}};</script> <script type="text/javascript"> var whenJqueryReadyInterval = null; // used to "break" the jquery check loop document.addEventListener('DOMContentLoaded', function initSearchBarAfterEvent() { // load searchbar resources after page finishes loading performance.mark('enter_initSearchBarAfterEvent()'); var whenJqueryReadyInterval = setInterval(function initSearchBarAfterJqueryLoad() { // load searchbar resources only after jQuery is ready // performance.mark('enter_initSearchBarAfterJqueryLoad()'); if (window.useV2Script) { console.log("[Searchbar]Using V2 Script"); if (!window.thermofisher || !window.thermofisher.search || !window.thermofisher.search.searchSelector || !window.thermofisher.search.searchProvider || !window.thermofisher.search.SignalsStatic){ return; } console.info('searchbar_init - Using v2 - no jQuery needed!'); window.searchbar.init(); clearInterval(whenJqueryReadyInterval); whenJqueryReadyInterval = null; } else { console.log("[Searchbar]Using jQuery"); if (window.jQuery && (!window.thermofisher || !window.thermofisher.search || !window.thermofisher.search.searchSelector || !window.thermofisher.search.searchProvider || !window.thermofisher.search.SignalsStatic || !window.thermofisher.search.searchFocusArea)){ return; } console.info('searchbar_init - jQuery loaded!'); window.searchbar.init(); clearInterval(whenJqueryReadyInterval); whenJqueryReadyInterval = null; } }, 100); }); </script>  <script type="text/javascript"> window.performance && window.performance.mark && window.performance.mark("header_9"); </script> </div> <span class="close" tabindex="0"></span> <span class="search-icon"> <svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 24 24"><path class="cls-1" d="M20.79,19.66l-4.58-4.58a7.53,7.53,0,1,0-1.49,1.34l4.66,4.66ZM6.54,14.11a5.56,5.56,0,1,1,3.93,1.62A5.52,5.52,0,0,1,6.54,14.11Z"/> </svg> </span> </div>  <script type="text/javascript"> window.performance && window.performance.mark && window.performance.mark("header_10"); </script> <div class="info-container" id="commerce-bar"> <ul>  <script type="text/javascript"> window.performance && window.performance.mark && window.performance.mark("header_11"); </script> <li id="order-status-1" class="order-status" data-util-index="1" data-analytics-text="Order Status"> <a class="user-utility-link cloud-button" href="/store/orders/solu">Order Status</a> </li>  <script type="text/javascript"> window.performance && window.performance.mark && window.performance.mark("header_12"); </script>  <script type="text/javascript"> window.performance && window.performance.mark && window.performance.mark("header_13"); </script> <li id="quick-order" class="quick-order" data-util-index="4" data-analytics-text="Quick Order"> <a href="/store/v2/quick-order"> Quick Order </a> </li>  <script type="text/javascript"> window.performance && window.performance.mark && window.performance.mark("header_14"); </script>  <script type="text/javascript"> window.performance && window.performance.mark && window.performance.mark("header_15"); </script> <li id="sign-in" class="account pragma-toggle-component" data-util-index="3" data-analytics-text="Sign in"> <span id="sign-in-toggle" class="down-caret-icon pragma-toggle" data-toggle="#sign-in,#full-bg" data-toggle-classes="open"> Sign in </span>  <script type="text/javascript"> window.performance && window.performance.mark && window.performance.mark("header_16"); </script> <div class="account-dd"> <div class="account"> <div class="cmp-p-ctaitem m--btn-primary m--block"> <div class="cmp-ctaitem"> <a class="cmp-ctaitem__anchor" href="/auth/initiate"> <span class="cmp-ctaitem__text">Sign in</span> </a> </div> </div> <div class="create-account pt-l1 pb-l1 border-bottom">Don't have an account ? <a href="/auth/create-account">Create Account</a> </div> <div class="create-account"> <ul> <li class="loyalty-text"><a href="#"></a></li> <li class="points"><a href="#"></a></li> <li> <a href="/auth/initiate">Account</a> </li> <li> <a href="/store/orders/solu">Check Order Status</a> </li> <li> <a href="https://apps.thermofisher.com ">Connect: Lab, Data, Apps</a> </li> <li> <a href="/auth/initiate">Custom Products & Projects</a> </li> <li> <a href="/auth/initiate">Instrument Management</a> </li> </ul>  </div> </div> </div>  <script type="text/javascript"> window.performance && window.performance.mark && window.performance.mark("header_17"); </script> </li>  <script type="text/javascript"> window.performance && window.performance.mark && window.performance.mark("header_18"); </script>  <script type="text/javascript"> window.performance && window.performance.mark && window.performance.mark("header_19"); </script> <li class="cart" data-util-index="5"> <a class = "pragma-remote-request" id="cart-link" href ="javascript:void(0)" data-remote-url = "/store/v2/minicart" data-remote-container ="#cart-sidebar" data-remote-failure-url="/store/cart"> <span class="count"></span> <svg data-toggle="#cart-sidebar,#full-bg" data-toggle-classes="open" class="pragma-toggle pragma-toggle-component" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 32 32"> <path class="cls-1" d="M11,25.55A1.76,1.76,0,1,1,9.27,23.8,1.76,1.76,0,0,1,11,25.55ZM24.65,23.8a1.76,1.76,0,1,0,1.76,1.75A1.75,1.75,0,0,0,24.65,23.8Zm1.46-2L29.46,9.64H10.24l.61,2.16H26.63l-2.16,7.81H9.76L5.59,4.94h-4l.62,2.15H4L8.14,21.77Z"/> </svg> </a> </li> </ul>  <script type="text/javascript"> window.performance && window.performance.mark && window.performance.mark("header_20"); </script> <div id="cart-sidebar" class="cart-dd pragma-toggle-component"> </div>  <script type="text/javascript"> window.performance && window.performance.mark && window.performance.mark("header_21"); </script> </div>  <script type="text/javascript"> window.performance && window.performance.mark && window.performance.mark("header_22"); </script>  <script data-inline-file-name='utilitybarbase.min.js' data-inline-site='tf'>/* Hash: 468bd07150dbbf Source: /tf/js/dist/utilitybarbase.min.js */ var utilitybarBase=function(e){return e.$utilityBar=document.getElementById("user-utility-bar"),e.$quickOrder=document.getElementById("hfBarQuickOrder"),e.$cloudLink=document.getElementById("hfCloud"),e.$accountDropdown=document.querySelectorAll("#hfGreetAnonymous,#hfGreetByName")[0],e.$partnerDashboard=document.querySelectorAll("#hfGreetDashboard")[0],e.$miniCart=document.getElementById("miniCartButton"),e.$viewNotifications=document.getElementById("notification-link"),e.$drawer1=document.getElementById("mobile-nav-drawer-1"),e.$drawer2=document.getElementById("mobile-nav-drawer-2"),e.Large=function(){e.$partnerDashboard&&e.$utilityBar.appendChild(e.$partnerDashboard),e.$cloudLink&&e.$utilityBar.appendChild(e.$cloudLink),e.$quickOrder&&e.$utilityBar.appendChild(e.$quickOrder),e.$miniCart&&e.$utilityBar.appendChild(e.$miniCart),e.$viewNotifications&&!document.documentMode&&e.$utilityBar.appendChild(e.$viewNotifications),e.$accountDropdown&&e.$utilityBar.appendChild(e.$accountDropdown)},e.Medium=function(){e.$accountDropdown&&e.$drawer2.appendChild(e.$accountDropdown),e.$partnerDashboard&&e.$drawer2.appendChild(e.$partnerDashboard),e.$quickOrder&&e.$utilityBar.appendChild(e.$quickOrder),e.$miniCart&&e.$utilityBar.appendChild(e.$miniCart),e.$viewNotifications&&!document.documentMode&&e.$utilityBar.appendChild(e.$viewNotifications)},e.Small=function(){e.$accountDropdown&&e.$drawer2.appendChild(e.$accountDropdown),e.$partnerDashboard&&e.$drawer2.appendChild(e.$partnerDashboard),e.$miniCart&&e.$utilityBar.appendChild(e.$miniCart),e.$viewNotifications&&!document.documentMode&&e.$utilityBar.appendChild(e.$viewNotifications),e.$quickOrder&&e.$drawer1.appendChild(e.$quickOrder)},e.init=function(){switch(currentBreakpoint=getCurrentViewportSize(),currentBreakpoint){case"xl":case"lg":e.Large();break;case"md":case"sm":e.Medium();break;case"xs":e.Small()}},e.initMiniCartCount=function(){var e=".minicart-number-holder-"+(window.innerWidth<=979?"mobile":"desktop"),i=document.querySelector(e),t=null!=i?i.parentNode.querySelector(".icon"):null,r=getCookie("MiniCartTotalItems");r&&r>0&&t&&(t.classList.remove("cart-icon-empty"),i.classList.remove("hidden"),i.classList.add("cart-items-number"),r>9999?(i.innerHTML=9999,t.classList.add("cart-icon-full"),i.classList.add("cart-items-number"),i.classList.remove("hidden")):(i.innerHTML=r,t.classList.remove("cart-icon-full")))},e.init(),e.initMiniCartCount(),e}(utilitybarBase||{});</script>  <script type="text/javascript"> window.performance && window.performance.mark && window.performance.mark("header_23"); </script> </div>  <script type="text/javascript"> window.performance && window.performance.mark && window.performance.mark("header_24"); </script>  <script data-inline-file-name='digitaldata.js' data-inline-site='tf'>/* Hash: 468bd07150dbbf Source: /tf/js/dist/digitaldata.js */ (function () { "use strict"; /** * Invoking a Function as a Method * define function as object methods * @type {Object} */ window.digitalData = { user: {}, page: {}, merchandising: {}, getQueryParam : function (param) { var index, key, value, hash; var hashes = window.location.href.slice(window.location.href.indexOf('?') + 1).split('&'); for (index = 0; index < hashes.length; index++) { hash = hashes[index].split('='); key = hash[0]; value = hash[1]; if (key.toUpperCase() === param.toUpperCase()) return value; } return ''; }, getValOnce: function (value, cookieName, expiry, timeUnit) { var currentDate = new Date; var currentCookieValue; // timeUnit of 'm' is minutes represented in milliseconds // thus 86400000 = 24 hours = 1 day var interval = timeUnit == 'm' ? 60000 : 86400000; cookieName = cookieName ? cookieName : 'digitaldata_gvo'; value = value ? value : ''; expiry = expiry ? expiry : 0; currentCookieValue = this.getCookie(cookieName); if (value) { currentDate.setTime(currentDate.getTime() + expiry * interval); this.setCookie(cookieName, value, expiry == 0 ? 0 : currentDate); } return value == currentCookieValue ? '' : value; }, getCookie: function (key) { var result = ""; var cookies = document.cookie ? document.cookie.split('; ') : []; for (var i = 0; i < cookies.length; i++) { var parts = cookies[i].split('='); var name = decodeURIComponent(parts.shift()); var cookie = parts ? parts.join('=') : []; // Prevent storing or parsing of a cookie that we couldn't decode. if (cookie && key === name) { // removes surrounding quotes if (cookie.indexOf('"') === 0) { // This is a quoted cookie as according to RFC2068, unescape... cookie = cookie.slice(1, -1).replace(/\\"/g, '"').replace(/\\\\/g, '\\'); } // parse utf8 characters try { cookie = decodeURIComponent(cookie); } catch (e) {} result = cookie; // we found it, don't bother looking at other cookies break; } } return result; }, setCookie : function(name, value, numDays){ if ( !numDays ) numDays = 31; var expires = new Date(); expires.setTime(expires.getTime() + (1000 * 60 * 60 * 24 * numDays)); document.cookie = name+ '=' + escape(value) + '; path=/; expires=' + expires.toGMTString() + '; domain=.' + this.getMasterDomain() + ';'; }, /** * get the master domain based on business rules */ getMasterDomain : function () { // default the master domain var masterDomain = 'thermofisher.com'; // check for alternate domain portion of URL var regexMatch = document.location.hostname.match(/\.(thermofisher)\.(cn)/i); if (regexMatch !== null) { masterDomain = regexMatch[1] + '.' + regexMatch[2]; } return masterDomain; }, /** * Check if init has been initiated once * @type {Boolean} */ initted: false, /** * @return {Array} method returns an array of a given object's key properties */ init: function () { this.page.country = this.getCookie("CK_ISO_CODE") || 'us'; this.page.language = this.getCookie('CK_LANG_CODE') || 'en'; this.page.siteName = 'thermo'; //hard coded this.initMerchandisingData(); this.initUserData(); this.displayDigitalData(); this.formSubmitEvent(); }, //specific function to set type of the page // need specific function to keep page type separate from other page attributes setPageType: function (type) { this.setPageAttribute('type', type); }, // generic function to set page attributes setPageAttribute: function (key, value) { this.page[key] = value; }, // display digitalData object displayDigitalData: function () { }, // specific function to add an object to digitalData addDigitDataObject: function (key, object) { this[key] = object; }, addChildObjectAttribute: function(child, key, value){ this[child][key] = value; }, initUserData: function(){ var gigyaCookie = this.getCookie("identity_uid"); this.user.gigyaId = ""; this.user.loginStatus = "anonymous"; if( gigyaCookie != ""){ this.user.gigyaId = gigyaCookie; this.user.loginStatus = "logged in"; } }, /** * Check if init has been initiated once * @type {Boolean} */ merchandisingDataInitted: false, initMerchandisingData: function () { // read cid and icid value from session cookie this.merchandising.icid = this.getCookie('s_ev21_tc'); this.merchandising.cid = this.getCookie('s_cmp_tc'); // EMID value this.merchandising.emid = this.getQueryParam("emid"); // referrer by domain if (typeof document.referrer !== 'undefined' && document.referrer.length > 0) { var masterDomain = this.getMasterDomain(); var refReg = document.referrer; var referrerDomain = refReg.match(/:\/\/([^/]+)\//); if (referrerDomain !== null && referrerDomain[1].indexOf(masterDomain) == -1) { this.merchandising.referrer = referrerDomain; } } document.addEventListener('registerMerchandisingData', function (event) { for (var key in event.detail) { console.log("Listener data copied", key, event.detail[key] ); digitalData.merchandising[key] = event.detail[key]; } // Map some analytics attributes to merchandising session attributes digitalData.merchandising.sessionId = digitalData.merchandising.analyticsVisitorID; digitalData.merchandising.s_vi_low = digitalData.merchandising.analyticsVisitorIDLow; digitalData.merchandising.s_vi_high = digitalData.merchandising.analyticsVisitorIDHigh; console.log("digitalData: Captured registerMerchandisingData event"); digitalData.merchandisingDataInitted = true; // Call emailCampaignRecord if the digitalDataAnalyticsListener object is loaded if (typeof digitalDataAnalyticsListener != "undefined") { console.log("digitalData: Calling email campaign record"); digitalDataAnalyticsListener.emailCampaignRecord(); } }); }, formSubmitEvent: function () { var formId = this.getQueryParam("form-submit-id"); if ((formId) && formId !== "" && formId !== null) { var eventDetail = { detail: { form: { id: formId } } }; var formSubmitEvent = new CustomEvent('formSubmit', eventDetail); console.log('form submit event started'); document.dispatchEvent(formSubmitEvent); console.log('form submit event fired', eventDetail); //flush grepToken from Session Storage sessionStorage.removeItem('grepTokenSO'); } }, modalVideoEvent: function (videoId) { if (((videoId) && videoId !== "" && videoId !== null)) { var eventDetail = { detail: { video: { playerId: videoId } } }; var modalVideoEvent = new CustomEvent('videoPlayerLoaded', eventDetail); document.dispatchEvent(modalVideoEvent); } }, customClickEvent: function (clickDetail) { if (((clickDetail) && clickDetail !== "" && clickDetail !== null)) { var eventDetail = { detail: { CustomLink: { linkName: clickDetail } } } var customClickEvent = new CustomEvent('customLinkClicks', eventDetail); document.dispatchEvent(customClickEvent); } } } })(); window.digitalData.init(); </script>  <script type="text/javascript"> window.performance && window.performance.mark && window.performance.mark("header_25"); </script> <script type="text/javascript"> var localizedStrings = { "ACCEPTANCE": "Acceptance of Terms of Use", "BTN_AGREE": "Agree", "BTN_DISAGREE": "Disagree", "PROCESSING_MESSAGE" :"processing ... please wait ...", "ADD_TO_CART_QUANTITY_ERROR":"You must provide a quantity to add an item to the cart", "ADD_TO_CART_VALID_QUANTITY_ERROR":"You must provide a valid quantity to add an item to the cart", "VIEW_CART" :"View cart & checkout", "VIEW_CONTACT_DETAIL" :"View Contact Details", "ADD_TO_CART_NOTIFICATION":"Add to Cart Notification", "UPDATE_CART" :"Update Cart", "PRINCIPAL_INVESTIGATOR":"Principal Investigator", "PRINCIPAL_INVESTIGATOR_TEAM_LEADER":"Principal Investigator or Team Leader", "PRINCIPAL_INVESTIGATOR_CHIEF":"Principal Investigator or Chief", "EMAIL_ERROR_1" :"Please Provide Collegues Email", "EMAIL_ERROR_2" :"Please enter a valid colleague email address", "EMAIL_ERROR_3" :"Please Provide Your Email", "EMAIL_ERROR_4" :"Please enter a valid email address", "ERROR_OCCURED_MESSAGE" :"The following errors occured", "NEXT" :"Next", "PREVIOUS" :"Prev", "IMAGE" :"Image", "SAVE_TO_LIST_ERROR_1" :"Please enter a list name.", "SAVE_TO_LIST_ERROR_2" :"Please enter a different list name that does not include the following: ?,/,\\,%,^,!", "MINICART_ERROR_1" :"Unable to connect to eCommerce system. Please try again later.", "MINICART_ERROR_2" :"Please enter a quantity in the range of 1 to 999.", "MINICART_ERROR_3" :"Could not add item(s) to cart.", "MINICART_ERROR_4" :"Could not remove item from cart.", "MINICART_ERROR_5" :"Could not create/restore cart.", "MINICART_ERROR_6" :"Unable to retrieve cart details. Please try again later.", "MINICART_MESSAGE_1" :"Adding item(s) to cart...", "MINICART_MESSAGE_2" :"Removing item(s) from cart...", "MINICART_CART_NAME_LABEL_1" :"Recently added to the", "MINICART_NOTE_1" : "Your total price and product details can be viewed in the cart.", MINICART_SUMMARY : "Cart summary", MINICART_PRICE : "Price", MINICART_PRODUCT : "Product", LIST_PRICE : "Price", YOUR_PRICE : "Your price", WEB_PRICE: "Online offer", PRICE_ENDS: "ends", SIGN_IN: "Sign in", //New mini cart CATALOG_NUMBER: "Catalog number:", CONTACT_US: "Contact us", RFQ: "Request quote", LEARN_WHERE_TO_BUY: "Learn where to buy", CURRENCY: "USD", //End new mini cart "CHANGE_CART" :"Change cart", "VIEW_ALL" :"View All", "ITEM" :"item", "ITEMS" :"items", "CLOSE" :"Close", "SUBTOTAL" :"Subtotal", "TOTAL" :"Total", "MANAGE_CART" :"Manage Cart", "FIELD" :"field", "GLOBAL_ERROR_1" :"Please choose one or both of the options for", "GLOBAL_ERROR_2" :"is not a valid e-mail address.", "GLOBAL_ERROR_3" :"Unsupported character(s) were found in field", "GLOBAL_ERROR_4" :"and will be replaced with plain text equivalents (where available). Please review the changes and try again.", "GLOBAL_ERROR_5" :"Please fill in the", "GLOBAL_ERROR_6" :"Quantities must be whole numbers greater than or equal to zero.", "GLOBAL_ERROR_7" :"is either not a number or a number less than zero, please provide a numerical quantity", "GLOBAL_ERROR_8" :"Reserved character | not allowed. Please remove and try again.", "required" : "One or more required fields are missing", "requireOneOfMany" : "At least one field in the group must be filled out", "password" : "Password does not conform to the password policy", "passwordConfirm" : "Password and Confirm Password do not match", "emailConfirm" : "Email and Confirm Email do not match", "secretConfirm" : "Secret Answer and Confirm Secret Answer do not match", "alphanumeric" : "Value must be alphanumeric", "phone" : "Phone number or Fax number provided were non-numeric values", "email" : "Email address provided is in an invalid format", "date" : "Date is in an invalid format (ex. MM/DD/YYYY)", "expirationDate" : "Expiration date provided is invalid", "currency" : "Currency is in an invalid format", "creditCard" : "Credit card number is invalid", "quantity" : "Quantity must in the range of 1 - 999", "acceptance" : "The terms and conditions must be accepted to continue", "checkboxes" : "At least one item must be selected", "twoOrMorecheckboxes" : "Merging carts requires multiple carts to be selected", "file" : "A file must be selected to upload", "NEW_USER" :"New user", "REGISTER_NOW" :"Register Now", "LOGIN_WIDGET_MESSAGE1" :"View your contract prices and real-time product availability.", "WELCOME" :"Welcome", "MY_ACCOUNT" :"My Account", "FAVORITES" :"Favorites", "SAVED_LISTS" :"Saved Lists", "ORDER_STATUS" :"Order Status", "LOGOUT" :"Logout", "APPROVALS" :"Approvals", "REMOVE" :"Remove", "QUANTITY" :"Qty", "EDIT" :"Edit", "SEARCH_BOX_TEXT" :"",//"Search by catalog number or keyword", "SELECT_LANGUAGE" :"Select a Language", "MY_MESSAGES" :"My Messages", "MESSAGE_ALERTS" :"Message Alerts", "B2B_NEW_WINDOW_ALERT" :"You are about to open a new browser window. \nClicking an external link on our site causes a new window to open. However, your shopping session will remain active in this window.Simply return here to continue shopping. \n Would you like to proceed?", "GREETING" :"", "SCMS_SHIP_TO_LAB" :"Ship To Lab", "SCMS_SHIP_TO_SC" :"Supply Center Order", "SCMS_SHIP_TO_SC_FOR_EU":"Supply Centre Order", "SUBMIT" :"Submit", "SUBMIT_ERROR_VALIDATE_EMAIL":"Sorry - we could not validate your email address. Please try again. ", "SUBMIT_ERROR_SERVER" :"We had an issue handling your request - please try again later.", "RECENT_SEARCHES" :"Recent searches", "inText" :"in", "searchSuggestions" :"Search suggestions", "RECENTLYVIEWED_TITLE" : "Recently Viewed Items", "RECENTLYVIEWED_DELETE" : "Remove", "RECENTLYVIEWED_TODAY" : "Today", "RECENTLYVIEWED_PAGINATE": "{C} of {T}", DF_MONTH_0:"January", DF_MONTH_1:"February", DF_MONTH_2:"March", DF_MONTH_3:"April", DF_MONTH_4:"May", DF_MONTH_5:"June", DF_MONTH_6:"July", DF_MONTH_7:"August", DF_MONTH_8:"September", DF_MONTH_9:"October", DF_MONTH_10:"November", DF_MONTH_11:"December", DF_WEEKDAY_0:"Sun", DF_WEEKDAY_1:"Mon", DF_WEEKDAY_2:"Tue", DF_WEEKDAY_3:"Wed", DF_WEEKDAY_4:"Thu", DF_WEEKDAY_5:"Fri", DF_WEEKDAY_6:"Sat", DF_FORMAT:"{0}, {2} {1}" }; var localizedImage = { "LOGIN_WIDGET_EXPAND":"/shared-static/images/buttons/loginWidgetExpand.gif", "LOGIN_WIDGET_MY_ACCOUNT_EXPAND":"/shared-static/images/buttons/loginWidgetMyAccountExpand.gif", "LOGIN_WIDGET_CONTRACT":"/shared-static/images/buttons/loginWidgetContract.gif", "LOGIN_WIDGET_MY_ACCOUNT_CONTRACT":"/shared-static/images/buttons/loginWidgetMyAccountContract.gif", "LOGOUT_BUTTON":"/shared-static/images/login/useraccount.gif", "CLOSE_SESSION_COOL":"/shared-static/images/login/Close-Session-Cool.JPG", "ICON_CLOSE":"/shared-static/images/login/icon_close.GIF" }; var localizedLink = { "B2B_CHECK_OUT_LINK":"/en/US/procurement/lt?cmd=ViewCart&ShoppingCartKey=", "B2B_MANAGE_CART_LINK":"/en/US/procurement/lt?cmd=OILDataDisplay&ShoppingCartKey=", "B2B_VIEW_ALL_LINK":"/en/US/procurement/lt?cmd=ViewCart&ShoppingCartKey=", "LIGGED_IN_CHECKOUT_LINK":"/en/US/direct/lt?cmd=ViewCart&ShoppingCartKey=", "LOGGED_IN_MANAGE_CART_LINK":"/en/US/direct/lt?cmd=OILDataDisplay&ShoppingCartKey=", "LOGGED_IN_VIEW_ALL_LINK":"/en/US/direct/lt?cmd=ViewCart&ShoppingCartKey=", "ANONYMOUS_CHECKOUT_LINK":"/en/US/adirect/lt?cmd=ViewCart&ShoppingCartKey=", "ANONYMOUS_MANAGE_CART_LINK":"/en/US/adirect/lt?cmd=OILDataDisplay&ShoppingCartKey=", "ANONYMOUS_VIEW_ALL_LINK":"/en/US/adirect/lt?cmd=ViewCart&ShoppingCartKey=", "PRODUCT_DETAIL_URL_B2B":"/en/US/procurement/lt?cmd=catProductDetail&productID=", "PRODUCT_DETAIL_URL_ANONYMOUS":"/en/US/adirect/lt?cmd=catProductDetail&productID=", "PRODUCT_DETAIL_URL_LOGGED_IN":"/en/US/direct/lt?cmd=catProductDetail&productID=", "MY_ACCOUNT_LINK_CSR":"/en/US/enterpriseMgr/lt?cmd=HomeDataDisplay", "QUICK_ORDER_ANONYMOUS":"/en/US/adirect/lt?cmd=IVGNQuickOrderLanding", "MY_ACCOUNT_LINK_B2B":"/en/US/procurement/lt?cmd=PartnerSysUserMyAccount", "ORDER_STATUS_LINK_B2B":"/en/US/procurement/lt?cmd=WorkspaceDataDisplay&_Tab=Ordered", "MY_ACCOUNT_LINK":"/en/US/direct/lt?cmd=PartnerSysUserMyAccount", "ORDER_STATUS_LINK":"/en/US/direct/lt?cmd=WorkspaceDataDisplay&_Tab=Ordered", "COMERGENT_CLOSE_SESSION_LINK":"/en/US/procurement/lt?cmd=PunchInOrder&mode=Cancel", "REGISTRATION_URL":"/en/US/adirect/lt?cmd=FullRegistrationData&GroupKey=103&Command=updateExecute&anonymousHomePageMsg=OnlineOrderingPageDisplay", "LIGGED_IN_CHECKOUT_LINK_SCMS":"/en/US/direct/lt?cmd=ViewCart&ShoppingCartKey=", "SCMS_CHECKOUT_SC":"/en/US/procurement/lt?cmd=SetSCMSAddress", "SCMS_CHECKOUT":"/en/US/procurement/lt?cmd=ViewCart&ShoppingCartKey=", "PSCMS_CHECKOUT_SC":"/en/US/procurement/lt?cmd=PSCMSCheckout", "GUEST_USER_AUTH_REDIRECT":"/en/US/procurement/lt?cmd=B2BMasterUserRegistration&operation=identifyUser", "GUEST_USER_AJAX_AUTH":"/en/US/procurement/lt?cmd=B2BMasterUserRegistration&operation=validateNLogin", "GUEST_USER_AJAX_AUTH_UNIQUE_EXPRESS":"/en/US/procurement/lt?cmd=ExpressUniqueUserEmailUpdate", "GUEST_USER_SEARCH_TOOL":"/en/US/direct/lt?cmd=WorkspaceDataDisplay&_Tab=Ordered" }; var localizedMasterUserPopoverSettings = { title:'', content_template: '<div><span class="master-user-popover-close-button">x</span><p class="content_fill">Please enter your email address to use this feature.</p>'+ '<form class="masterUserEmailSubmit form-inline" action="" method="post" onsubmit="return false;">'+ '<div class="auth-error-messaging">'+ '<small class="text-error error-form error-required hide">'+localizedStrings.EMAIL_ERROR_4+'</small>'+ '<small class="text-error error-form error-invalid hide">'+localizedStrings.EMAIL_ERROR_4+'</small>'+ '<small class="text-error error-form error-register hide">'+localizedStrings.SUBMIT_ERROR_SERVER+'</small>'+ '<small class="text-error error-form error-communicate hide">'+localizedStrings.SUBMIT_ERROR_VALIDATE_EMAIL+'</small>'+ '</div>'+ '<span class="control-group">'+ '<input type="text" name="masterUserEmailAddress" class="masterUserEmailAddress input-medium" />'+ '</span> '+ '<input type="button" class="btn btn-primary button primary-button" value="'+localizedStrings.SUBMIT+'" />'+ '<input type="hidden" name="return-url" class="return-url" />'+ '<input type="hidden" name="return-url-is-function-call" class="return-url-is-function-call" />'+ '</form>', content_ordering: '<p class="content_fill content_ordering_fill">Please enter your email address to see order history. Or, you can <a href="#" class="link_search_tool">use the search tool</a> to look for individual orders.</p>', html:true, trigger:'manual', template: '<div class="popover" style="width: 300px; max-width: none;"><div class="arrow"></div><div class="popover-inner"><h3 class="popover-title"></h3><div class="popover-content"><p></p></div></div></div>' }; </script>  <script type="text/javascript"> window.performance && window.performance.mark && window.performance.mark("header_26"); </script>   <script type="text/javascript"> window.performance && window.performance.mark && window.performance.mark("globalHeader:renderEnd"); </script> <div class="full-bg" id="full-bg"></div> <div class="search-bg" id="search-bg"></div> </div> </header>  <script>var useNewJquery = 'PatternLibrary';</script> <link href="/etc/designs/lifetech/clientlibs/base.min.css" rel="stylesheet" rel="preload" as="style" /> <link href="/etc/designs/lifetech/clientlibs/base-responsive.css" rel="stylesheet" rel="preload" as="style" /> <script type="text/javascript" src="/etc/designs/lifetech/clientlibs/base-jquery.min.js?version=Local&time=20240917&build-time=2024-11-22T02:34:20+0000"></script> <script type="text/javascript" src="/etc/designs/lifetech/clientlibs/base-bootstrap.min.js?version=Local&time=20240917&build-time=2024-11-22T02:34:20+0000"></script> <script src="/shared-static/scripts/global-variables.js"></script> <script src="/shared-static/scripts/global-functions.js"></script> <script src="/shared-static/scripts/environmenturl.js"></script> <script src="/etc/designs/komodo/clientlibs/s_code.js"></script> <script src="/shared-static/scripts/jquery.ivgnModal.js"></script>  <div class="genomic-product-search genomic-product-search-contents content group container page-PDP"> <div class="contents row-fluid"> <div class="span12">    <script type="text/javascript"> if (typeof window.$m === 'undefined' || !window.$m) { window.$m = {}; } window.$m.productName ='CD11b Monoclonal Antibody (M1\/70), PE-Cyanine5, eBioscience\u2122'; if (typeof window.$mangular === 'undefined' || !window.$mangular) { window.$mangular = {}; } window.$mangular.productCategory = 'Antibody'; window.$mangular.productType = 'antibody'; window.$mangular.productSubType = 'Antibody'; window.$mangular.antibodyAspireLink = '/us/en/home/products-and-services/aspire-member-program.html?cid=bid_asp_sbu_r02_co_cp1438_pjt7721_col015466_0wm_tfs_df_awa_at_s00_PCAAntibodyPDP2021'; window.$mangular.ComergentHost = 'www.thermofisher.com' window.$mangular.contryCode = 'sg'; window.$mangular.languageCode = 'en'; window.$mangular.allowShowMoreShowLess = 'false'; window.$mangular.newImageGalleryElisa ='true'; window.$mangular.videoInImageGallery = 'true'; window.$mangular.relatedProducstWidgetV2 ='true'; window.$mangular.brightcoveAccountId = '3663210762001'; window.$mangular.referenceSortByFilterRemoved = 'true'; window.$mangular.techSupportModalEmailFormUrl = 'https://www.thermofisher.com/sg/en/home/technical-resources/contact-us/ext-antibody-technical-support.15-0112-82.html'; window.$mangular.referenceFilterEnabled = 'true'; window.$mangular.galleryFilterEnabled = 'true'; window.$mangular.isB2BUser = 'false'; window.$mangular.isFullSizeImageEnabled = 'true'; window.$mangular.productWebName = 'CD11b Monoclonal Antibody (M1\/70), PE-Cyanine5, eBioscience\u2122'; window.$mangular.chatBaseApiUrl = 'https://chat-api.thermofisher.com'; window.$mangular.newChatGateWayEnabled = 'false'; window.$mangular.countryCode = 'sg'; window.$mangular.promoAdEnabled = 'true'; </script> <link rel="stylesheet" type="text/css" href="/order/genome-database/assets/css/font-common.css?version=Local&time=20240917&build-time=2024-11-22T02:34:20+0000"/> <link rel="stylesheet" type="text/css" href="/order/genome-database/assets/js/angular/dist/pdp/antibody.pdp.dist.css?version=Local&time=20240917&build-time=2024-11-22T02:34:20+0000"/> <link rel="stylesheet" type="text/css" href="/order/genome-database/assets/core/dist/angular/gallery-module/gallery-module.css?version=Local&time=20240917&build-time=2024-11-22T02:34:20+0000"/> <svg xmlns="http://www.w3.org/2000/svg" display="none"> <style> .fill-color { fill:var(--fill-svg-path); } </style> <symbol id="icon-data-sheet" viewBox="0 0 21 17"> <g stroke="none" stroke-width="1" fill="none" fill-rule="evenodd"> <g transform="translate(-116.000000, -584.000000)"> <g transform="translate(116.000000, 584.000000)"> <path class="fill-color" d="M0,16.5249711 L5.00100002,16.5249711 L5.00100002,3.30482752 L0,3.30482752 L0,16.5249711 Z M1.66700001,14.8571376 L3.33400002,14.8571376 L3.33400002,4.97182752 L1.66700001,4.97182752 L1.66700001,14.8571376 Z" ></path> <path class="fill-color" d="M7.50150003,16.5249711 L12.5025001,16.5249711 L12.5025001,8.26248554 L7.50150003,8.26248554 L7.50150003,16.5249711 Z M9.16850004,14.8571376 L10.8355,14.8571376 L10.8355,9.92865205 L9.16850004,9.92865205 L9.16850004,14.8571376 Z" ></path> <path class="fill-color" d="M15.0030001,16.5249711 L20.0040001,16.5249711 L20.0040001,0 L15.0030001,0 L15.0030001,16.5249711 Z M16.6700001,14.8579711 L18.3370001,14.8579711 L18.3370001,1.66700001 L16.6700001,1.66700001 L16.6700001,14.8579711 Z" ></path> </g> </g> </g> </symbol> <symbol id="icon-protocols" viewBox="0 0 22 20"> <g stroke="none" stroke-width="1" fill="none" fill-rule="evenodd"> <g transform="translate(-1.000000, -2.000000)"> <path class="fill-color" d="M17.8,2.5l3.8,3.8c0.5,0.5,0.5,1.4,0,1.9l-5.4,5.4c-0.5,0.5-1.4,0.5-1.9,0L13,12.3l-1.1,1.1 l1.2,1.2c0.5,0.5,0.5,1.4,0,1.9l-5.4,5.4c-0.5,0.5-1.4,0.5-1.9,0l-3.8-3.8c-0.5-0.5-0.5-1.4,0-1.9l5.4-5.4c0.5-0.5,1.4-0.5,1.9,0 l1.1,1.1l1.1-1.1l-1.1-1.1c-0.5-0.5-0.5-1.4,0-1.9l5.4-5.4C16.4,1.9,17.3,1.9,17.8,2.5z M8.4,12.8L4,17.2l2.8,2.8l4.5-4.5 l-0.8-0.8L9.3,16l-1.4-1.4L9,13.4L8.4,12.8z M16.8,4.3l-4.5,4.5L13,9.4l1.1-1.1l1.4,1.4l-1.1,1.1l0.8,0.8l4.5-4.5L16.8,4.3z" /> </g> </g> </symbol> <symbol id="icon-create-citation" viewBox="0 0 23 21"> <g stroke="none" stroke-width="1" fill="none" fill-rule="evenodd"> <g transform="translate(-260.000000, -582.000000)"> <path class="fill-color" d="M272.324583,582 L262.476833,593.568087 L261.673833,598.68327 L260,600.221115 L260,602 L282,602 L282,600.221115 L262.672083,600.221115 L262.858167,600.047674 L268.246333,598.191408 L278.095917,586.624211 L272.324583,582 Z M264.041583,594.345459 L272.57025,584.505559 L275.51275,586.862581 L266.983167,596.701592 L264.041583,594.345459 Z M263.96,596.402739 L265.097583,597.314418 L263.71525,597.813395 L263.96,596.402739 Z" id="Page-1" transform="translate(271.000000, 592.000000) rotate(-1.000000) translate(-271.000000, -592.000000) "></path> </g> </g> </symbol> <symbol id="icon-qna" viewBox="0 0 19 22"> <path class="fill-color" d="M8,11.34h2v2H8ZM6,7.21a3.06,3.06,0,0,1,.23-1.15,2.56,2.56,0,0,1,1.52-1.5A3.14,3.14,0,0,1,9,4.34a4,4,0,0,1,1.45.23,2.87,2.87,0,0,1,.93.56,1.94,1.94,0,0,1,.51.73,2,2,0,0,1,.15.72,2.42,2.42,0,0,1-.15.92,2.18,2.18,0,0,1-.38.61,2.59,2.59,0,0,1-.5.44l-.52.36a2.09,2.09,0,0,0-.43.41,1.09,1.09,0,0,0-.24.58v.44H8.13V9.82A2.46,2.46,0,0,1,8.34,9a2.36,2.36,0,0,1,.38-.57A2.88,2.88,0,0,1,9.18,8c.17-.12.32-.24.45-.35A2,2,0,0,0,10,7.27a1.07,1.07,0,0,0,.12-.53A1.05,1.05,0,0,0,9.81,6a1.07,1.07,0,0,0-.76-.25,1.26,1.26,0,0,0-.57.12,1,1,0,0,0-.39.33,1.2,1.2,0,0,0-.22.47,2.21,2.21,0,0,0-.08.59Z"/> <g> <path class="fill-color" d="M4.1,22V16.55H0V0H19V16.55H11.43ZM2,14.55H6.1V18l4.67-3.46H17V2H2Z"/> </g> </symbol> <symbol id="icon-tech-support" viewBox="0 0 25 20"> <g stroke="none" stroke-width="1" fill="none" fill-rule="evenodd"> <g transform="translate(-424.000000, -582.000000)" fill-rule="nonzero"> <g transform="translate(424.000000, 582.000000)"> <g> <path class="fill-color" d="M19.8028437,4.49241085 L20.6158492,4.49241085 L23,4.49241085 L23,2 L16,2 L16,4.49241085 L19.0144231,4.49241085 L19.0144231,5.26028879 L19.8028437,4.49241085 Z M20.6158492,6.49241085 L17.0144231,10 L17.0144231,6.49241085 L14,6.49241085 L14,0 L25,0 L25,6.49241085 L20.6158492,6.49241085 Z" id="Combined-Shape"></path> <path class="fill-color" d="M8.5,14 C6.01471863,14 4,11.9852814 4,9.5 C4,7.01471863 6.01471863,5 8.5,5 C10.9852814,5 13,7.01471863 13,9.5 C13,11.9852814 10.9852814,14 8.5,14 Z M8.5,12 C9.88071187,12 11,10.8807119 11,9.5 C11,8.11928813 9.88071187,7 8.5,7 C7.11928813,7 6,8.11928813 6,9.5 C6,10.8807119 7.11928813,12 8.5,12 Z" id="Oval-2"></path> <path class="fill-color" d="M0.613568084,20 L1.0511019,18.6844174 C2.50568865,14.3107461 5.04750487,12 8.5999882,12 C12.1640717,12 14.6451209,14.3259794 15.9580242,18.7133126 L16.3430636,20 L0.613568084,20 Z M13.5943938,18 C12.4931866,15.2747206 10.8472364,14 8.5999882,14 C6.34912378,14 4.64995118,15.278916 3.45203497,18 L13.5943938,18 Z" id="Path-7"></path> </g> </g> </g> </g> </symbol> <symbol id="icon-published-figures" viewBox="0 0 14 17"> <g stroke="none" stroke-width="1" fill="none" fill-rule="evenodd"> <g transform="translate(-119.000000, -363.000000)" fill="#222222"> <path d="M131.133333,378.111122 L121.8,378.111122 C121.338,378.111122 120.969333,377.763568 120.896533,377.315904 L129.442133,377.315904 L130.375467,377.315904 L130.375467,376.371465 L130.375467,366.678685 L131.133333,366.678685 L131.133333,378.111122 Z M121.8,364.888973 L128.507867,364.888973 L128.507867,375.427025 L120.866667,375.427025 L120.866667,365.833412 C120.866667,365.312082 121.285733,364.888973 121.8,364.888973 Z M130.375467,364.789807 L130.375467,363.944534 L130.375467,363.000094 L129.442133,363.000094 L121.8,363.000094 C120.320667,363.000094 119.122267,364.163644 119.0196,365.63508 C119.015867,365.66908 119,365.698357 119,365.734246 L119,365.833412 L119,376.371465 L119,377.166682 L119,377.315904 L119.014933,377.315904 C119.093333,378.810007 120.303867,380 121.8,380 L133,380 L133,364.789807 L130.375467,364.789807 Z" id="Page-1"></path> </g> </g> </symbol> <symbol id="icon-references" viewBox="0 0 13 19"> <g stroke="none" stroke-width="1" fill="none" fill-rule="evenodd"> <g transform="translate(-375.000000, -465.000000)" fill="#333333" fill-rule="nonzero"> <path d="M386,466.999459 C385.999749,466.999679 383.000669,466.999859 377.00276,467 C377.001684,467 377.000764,471.346542 377,480.039626 L381.5,476.720461 L386,480.039626 L386,466.999459 Z M375,466.997422 C375,465.894276 375.893543,465 377.00276,465 L385.99724,465 C387.103334,465 388,465.890925 388,466.997422 L388,484 L381.5,479.205651 L375,484 L375,466.997422 Z" id="Rectangle-11"></path> </g> </g> </symbol> <symbol id="icon-performance-guarantee" viewBox="0 0 17 20"> <defs> <style>.cls-1{fill:#1e8ae7;}.cls-2{fill:#fff;}</style> </defs> <polygon class="cls-1" points="0 0 0 15.63 8.55 20 17 15.63 17 0 0 0"/> <g> <g> <g> <polygon class="cls-2" points="7.38 12.66 3.34 9.07 4.66 7.58 7.38 9.98 12.34 5.58 13.66 7.07 7.38 12.66"/> </g> </g> </g> </symbol> <symbol id="icon-advanced-verification" viewBox="0 0 14 14"> <g stroke="none" stroke-width="1" fill="none" fill-rule="evenodd"> <g transform="translate(-143.000000, -531.000000)" fill="#E71316"> <g transform="translate(135.000000, 526.000000)"> <g transform="translate(8.000000, 5.000000)"> <g id="advanced-verification-icon"> <polygon id="Path-8" fill-rule="nonzero" points="9.82562882 4.6077322 10.8059501 5.70805727 6.18058487 9.82897051 3.19404987 7.16815328 4.17437118 6.0678282 6.18058487 7.85524002"></polygon> <path d="M7,12.5263158 C10.0520999,12.5263158 12.5263158,10.0520999 12.5263158,7 C12.5263158,3.94790007 10.0520999,1.47368421 7,1.47368421 C3.94790007,1.47368421 1.47368421,3.94790007 1.47368421,7 C1.47368421,10.0520999 3.94790007,12.5263158 7,12.5263158 Z M7,14 C3.13400675,14 0,10.8659932 0,7 C0,3.13400675 3.13400675,0 7,0 C10.8659932,0 14,3.13400675 14,7 C14,10.8659932 10.8659932,14 7,14 Z" id="Oval-3-Copy" fill-rule="nonzero"></path> </g> </g> </g> </g> </g> </symbol> <symbol id="icon-select" viewBox="0 0 32 32"> <path d="M16 22.976l-15.68-13.952h31.36z"></path> </symbol> <symbol id="icon-technical-guide-and-protocol" viewBox="0 0 24 24"> <path class="fill-color" d="M13.9,1.1c0.6,0,1.2,0.3,1.4,0.9l0.6,1.1H20v19.6H3.7V3.1h4.1l0.6-1.1 c0.3-0.5,0.8-0.9,1.4-0.9H13.9z M6.9,5.1l-1.2,0v15.6H18V5.1l-1.2,0c0.1,0.9-0.6,1.7-1.6,1.7H8.5C7.5,6.8,6.8,6,6.9,5.1z M14.8,13.3v2H7.9v-2H14.8z M15.8,10v2H7.9v-2H15.8z M13.7,3.1h-3.6L9.2,4.8h5.3L13.7,3.1z"/> </symbol> <symbol id="icon-sale-tag" viewBox="0 0 17 17"> <path d="M6.85,1H1V6.85L10.17,16,16,10.17ZM4.69,4.69a.88.88,0,1,1,0-1.24A.86.86,0,0,1,4.69,4.69Z"/> </symbol> <symbol id="tooltip-info-icon" viewBox="0 0 16 16" fill="none"> <path d="M8 3C10.76 3 13 5.24 13 8C13 10.76 10.76 13 8 13C5.24 13 3 10.76 3 8C3 5.24 5.24 3 8 3ZM8 1C4.13 1 1 4.13 1 8C1 11.87 4.13 15 8 15C11.87 15 15 11.87 15 8C15 4.13 11.87 1 8 1Z" fill="#0071D0"/> <path d="M7 7V12H9V7H7Z" fill="#0071D0"/> <path d="M7 4V6H9V4H7Z" fill="#0071D0"/> </symbol> <symbol id="tooltip-icon-new" width="16" height="16" viewBox="0 0 16 16" fill="none" xmlns="http://www.w3.org/2000/svg"> <path d="M8 3C10.76 3 13 5.24 13 8C13 10.76 10.76 13 8 13C5.24 13 3 10.76 3 8C3 5.24 5.24 3 8 3ZM8 1C4.13 1 1 4.13 1 8C1 11.87 4.13 15 8 15C11.87 15 15 11.87 15 8C15 4.13 11.87 1 8 1Z" fill="#70707A"></path> <path d="M7 7V12H9V7H7Z" fill="#70707A"></path> <path d="M7 4V6H9V4H7Z" fill="#70707A"></path> </symbol> <symbol id="supply-center-icon" viewBox="0 0 14 14" fill="none"> <path d="M13.6352 4.98228H12.4043C12.2237 4.98228 12.0763 4.83405 12.0763 4.65247C12.0763 4.47089 12.2237 4.32267 12.4043 4.32267H13.8894C13.9042 4.32267 13.9189 4.32267 13.9337 4.32637C13.9374 4.32637 13.9374 4.32637 13.941 4.32637C13.9558 4.33008 13.9668 4.33008 13.9816 4.33378C13.9926 4.27079 14 4.20779 14 4.14479V3.70752H12.1021C11.9216 3.70752 11.7742 3.55929 11.7742 3.37771C11.7742 3.19613 11.9216 3.04791 12.1021 3.04791H14V2.43276H11.7999C11.6194 2.43276 11.472 2.28453 11.472 2.10295C11.472 1.92137 11.6194 1.77315 11.7999 1.77315H14V1.25805C14 0.628086 13.4914 0.116699 12.865 0.116699H9.98684C9.36036 0.116699 8.8518 0.628086 8.8518 1.25805V4.1522C8.8518 4.78217 9.36036 5.29356 9.98684 5.29356H12.865C13.1635 5.28985 13.4325 5.17127 13.6352 4.98228ZM2.1374 9.58476C0.958147 9.58476 0 10.5445 0 11.7341C0 12.9236 0.958147 13.8834 2.1374 13.8834C3.31666 13.8834 4.27481 12.9236 4.27481 11.7341C4.27481 10.5445 3.32035 9.58476 2.1374 9.58476ZM11.4351 9.58476C10.2522 9.58476 9.29402 10.5445 9.29402 11.7341C9.29402 12.9236 10.2522 13.8834 11.4351 13.8834C12.6181 13.8834 13.5762 12.9236 13.5762 11.7341C13.5762 10.5445 12.6181 9.58476 11.4351 9.58476Z" fill="#E71316"/> <path fill-rule="evenodd" clip-rule="evenodd" d="M3.96989 9.2373L2.16784 11.483L1.70897 11.1106L3.51102 8.86497L3.96989 9.2373Z" fill="#E71316"/> <path d="M1.60305 8.52493C3.41616 8.19883 5.20347 9.39947 5.31772 11.5488C5.3214 11.6488 5.40616 11.7304 5.50566 11.7304H8.04475C8.15162 11.7304 8.23638 11.6414 8.23638 11.534C8.19953 10.3889 8.83706 7.94684 13.1008 7.75044C13.1708 7.74673 13.1966 7.65409 13.134 7.61703C8.59384 4.85629 6.51908 7.4688 6.46012 7.26128C6.15794 6.2311 3.46775 5.90129 1.69887 7.56886C1.63991 7.56886 1.61779 7.76896 1.57357 8.49899C1.57357 8.51752 1.58831 8.52863 1.60305 8.52493Z" fill="#E71316"/> <path fill-rule="evenodd" clip-rule="evenodd" d="M8.04335 6.19454C9.22408 5.88996 10.9582 5.94786 13.2854 7.36267C13.6173 7.56116 13.4544 8.02859 13.1163 8.04648L13.1153 8.04654L13.1143 8.04658C11.0382 8.14221 9.89727 8.78067 9.27624 9.48338C8.65091 10.1909 8.51438 11.0068 8.53104 11.5244L8.53119 11.5292V11.534C8.53119 11.7977 8.3217 12.0268 8.04475 12.0268H5.50566C5.24976 12.0268 5.03437 11.8219 5.02322 11.5628C4.91822 9.60551 3.3074 8.52267 1.66058 8.81575C1.44688 8.86034 1.27876 8.68563 1.27876 8.49899V8.48997L1.2793 8.48096C1.30123 8.11892 1.31835 7.87521 1.33838 7.72161C1.3479 7.64863 1.36074 7.57251 1.38401 7.50902C1.39546 7.47776 1.41772 7.42574 1.46177 7.37776C1.48144 7.35635 1.5054 7.336 1.53324 7.319C2.47317 6.45193 3.64586 6.10402 4.63038 6.10696C5.12861 6.10845 5.59219 6.19975 5.96108 6.3711C6.21127 6.48732 6.43559 6.64957 6.5867 6.86018C6.63313 6.82917 6.68372 6.79591 6.73271 6.76502C7.02301 6.58198 7.45814 6.3455 8.04335 6.19454ZM6.17724 7.34478C6.13481 7.20068 5.99437 7.03969 5.71381 6.90936C5.43802 6.78125 5.06183 6.70116 4.62863 6.69987C3.77278 6.69732 2.74721 7.00218 1.92874 7.75877C1.927 7.76968 1.92507 7.78289 1.923 7.79871C1.91194 7.88353 1.90121 8.00831 1.88882 8.18848C3.71762 8.03347 5.44218 9.28953 5.6057 11.4339H7.94013C7.94191 10.8059 8.12772 9.89038 8.8355 9.08952C9.50117 8.3363 10.5991 7.7177 12.3509 7.51331C10.467 6.52491 9.09774 6.53466 8.18987 6.76886C7.6815 6.89999 7.30313 7.10519 7.04595 7.26735C6.95868 7.32237 6.89955 7.36272 6.84528 7.39974C6.80942 7.42421 6.77567 7.44723 6.73734 7.47208C6.70477 7.4932 6.65044 7.52796 6.5946 7.54814C6.5711 7.55663 6.49901 7.5815 6.4108 7.56282C6.35949 7.55195 6.30402 7.52647 6.25706 7.47976C6.21225 7.4352 6.18898 7.38508 6.17724 7.34478ZM1.55587 8.23226C1.55319 8.2327 1.55051 8.23318 1.54782 8.2337L1.55115 8.2331C1.55272 8.23282 1.55429 8.23254 1.55587 8.23226Z" fill="#E71316"/> <path fill-rule="evenodd" clip-rule="evenodd" d="M4.49592 4.76364C4.4496 4.47087 4.44944 4.4709 4.44927 4.47092L4.44887 4.47099L4.44785 4.47115L4.44497 4.47163C4.44268 4.47202 4.43965 4.47254 4.4359 4.4732C4.42841 4.47453 4.41806 4.47644 4.40503 4.47899C4.37898 4.48408 4.3422 4.49178 4.29627 4.50266C4.2045 4.52439 4.07568 4.55892 3.92252 4.611C3.61719 4.71483 3.20952 4.89027 2.80491 5.17732C1.98407 5.75966 1.19256 6.79295 1.2754 8.54641C1.28313 8.70995 1.42124 8.83623 1.58388 8.82846C1.74652 8.82069 1.8721 8.68181 1.86437 8.51827C1.79244 6.99589 2.46395 6.14483 3.14482 5.66179C3.49106 5.41615 3.84392 5.26363 4.1114 5.17267C4.24465 5.12736 4.35531 5.0978 4.43142 5.07978C4.46942 5.07078 4.49869 5.06469 4.51769 5.06097C4.52719 5.05911 4.53411 5.05785 4.53827 5.05711C4.54035 5.05674 4.54174 5.05651 4.54241 5.05639C4.5426 5.05636 4.54273 5.05634 4.5428 5.05633C4.7033 5.03034 4.81263 4.87857 4.78707 4.71707C4.76149 4.55537 4.6104 4.44515 4.4496 4.47087L4.49592 4.76364Z" fill="#E71316"/> </symbol> <symbol id="external-link" viewBox="0 0 14 14" fill="none"> <path d="M10 10V12H2V4H4V2H0V14H12V10H10Z" fill="#0071D0"/> <path fill-rule="evenodd" clip-rule="evenodd" d="M7.00002 0V2H10.59L4.02002 8.57L5.44002 9.98L12 3.41V7H14V0H7.00002Z" fill="#0071D0"/> </symbol> </svg> <svg xmlns="http://www.w3.org/2000/svg" display="none"> <symbol id="filters-icon-caret-down" viewBox="0 0 32 32"> <path d="M16 22.976l-15.68-13.952h31.36z"/> </symbol> <symbol id="filters-icon-close" viewBox="0 0 10 10"> <line x1="1" y1="1" x2="9" y2="9"/> <line x1="1" y1="9" x2="9" y2="1"/> </symbol> <symbol id="filters-icon-caret-right" viewBox="0 0 32 32"> <path d="m16,22.976l-15.68,-13.952l31.36,0l-15.68,13.952z" transform="rotate(-90 16,16) "/> </symbol> <symbol id="filters-icon-back" viewBox="0 0 20 20"> <g stroke-width="2"> <line x1="2" y1="10" x2="9" y2="3"/> <line x1="1" y1="10" x2="18" y2="10"/> <line x1="2" y1="10" x2="9" y2="17"/> </g> </symbol> </svg> <div class="antibody-new-pdp"> <div class="magellan-grid pdp non-touch"> <div class="pdp-modals"> <div id="benchsciDisclaimerModal" class="modal fade benchsciDisclaimer-Modal" role="dialog" aria-labelledby="benchsci-DisclaimerModal-title">  <div class="modal-content" role="document"> <div class="modal-header-disclaimer"> <h2 class="pdp-sub-heading modal-title disclaimer-modal-title" id="benchsci-DisclaimerModal-title">Disclaimer</h2> <img class="disclaimer-close-cross" data-toggle="modal" data-target="#benchsciDisclaimerModal" src="/order/genome-database/assets/img/x_close.svg"/> </div> <div class="modal-body"> <p> Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented. </p> </div> </div> </div> </div> <div class="pdp-components"> <div id="pdp-components" ng-controller="pdpMainController as $ctrl">  <div block-ui="main" class="block-ui-main"></div> <div class="hero hero-loading-height" ng-class="{'is-loaded':$ctrl.isLoaded, 'with-banner': 'false' == 'true'}"> <div class="container"> <div class="hero-content"> <div class="brand-breadcrumb to-hide-on-mobile row"> <div class="large-span-12 medium-span-12 target_page_breadcrumbs"> <div class="breadcrumb breadcrumb-hide-restricted-only"> <ul class="breadcrumb breadcrumb-hide-restricted-only hero-breadcrumbs"> <li class="active"> <a href="/us/en/home/life-science/antibodies/primary-antibodies.html" target="_self"> Primary Antibodies </a> <span class="divider">&rsaquo;</span> </li> <li class="active"> <a href="/antibody/primary/target/cd11b" target="_self" class="targetLink"> CD11b Antibodies</a> </li> </ul> </div> </div> </div> <svg xmlns="http://www.w3.org/2000/svg" display="none"> <symbol id="close-drawer-icon" viewBox="0 0 22.74 22.74"> <line x1="1.67" y1="1.67" x2="21.33" y2="21.33" style="fill:none;stroke:#555759;stroke-linecap:square;stroke-width:2px"/> <line x1="21.07" y1="1.41" x2="1.41" y2="21.07" style="fill:none;stroke:#555759;stroke-linecap:square;stroke-width:2px"/> </symbol> <symbol id="info-icon" viewBox="0 0 32 32"> <path fill="#1e8ae7" d="M16 10.688c-1.152 0-2.048-0.896-2.048-2.048s0.896-2.048 2.048-2.048c1.152 0 2.048 0.896 2.048 2.048 0 1.088-0.96 2.048-2.048 2.048zM17.792 22.976c0 0.768-0.064 1.152-0.256 1.536-0.256 0.576-0.832 0.896-1.6 0.896-0.704 0-1.28-0.32-1.6-0.896-0.192-0.384-0.256-0.768-0.256-1.536v-8.256c0-0.768 0.064-1.152 0.256-1.536 0.256-0.576 0.832-0.896 1.6-0.896 0.704 0 1.28 0.32 1.6 0.896 0.192 0.384 0.256 0.768 0.256 1.536v8.256zM16 0.64c-8.512 0-15.36 6.848-15.36 15.36s6.848 15.36 15.36 15.36c8.512 0 15.36-6.848 15.36-15.36s-6.848-15.36-15.36-15.36z"></path> </symbol> <symbol id="info-orange-icon" viewBox="0 0 32 32"> <path fill="#ed7700" d="M16 10.688c-1.152 0-2.048-0.896-2.048-2.048s0.896-2.048 2.048-2.048c1.152 0 2.048 0.896 2.048 2.048 0 1.088-0.96 2.048-2.048 2.048zM17.792 22.976c0 0.768-0.064 1.152-0.256 1.536-0.256 0.576-0.832 0.896-1.6 0.896-0.704 0-1.28-0.32-1.6-0.896-0.192-0.384-0.256-0.768-0.256-1.536v-8.256c0-0.768 0.064-1.152 0.256-1.536 0.256-0.576 0.832-0.896 1.6-0.896 0.704 0 1.28 0.32 1.6 0.896 0.192 0.384 0.256 0.768 0.256 1.536v8.256zM16 0.64c-8.512 0-15.36 6.848-15.36 15.36s6.848 15.36 15.36 15.36c8.512 0 15.36-6.848 15.36-15.36s-6.848-15.36-15.36-15.36z"></path> </symbol> </svg> <div class="brand-info"> <p class="brand-name" itemprop="brand">Invitrogen</p> </div> <h1 class="product-name">CD11b Monoclonal Antibody (M1/70), PE-Cyanine5, eBioscience™</h1> <div class="details-hero" onclick="window.THERMO_FISHER.pdp.inp.toggleImagesAdvVerificationPublishedFigures(event, this)"> <a class="link published-link animated-scroll " href="#image-gallery" onclick="window.THERMO_FISHER.pdp.inp.publishedFiguresHero(event, this)"> <svg class="svg-icon published-figures-icon"> <use href="#icon-published-figures"></use> </svg> 98 Published Figures </a> </div> <div class="details-hero"> <a class="link references-link animated-scroll " href="#references-component-id" onclick="window.THERMO_FISHER.pdp.inp.referencesHero(event, this)"> <svg class="svg-icon references-icon"> <use href="#icon-references"></use> </svg> 289 References </a> </div> <div class="details-hero"> <a class="btn hero-btn hero-view-other" href="/antibody/primary/target/cd11b"> View all (192) CD11b antibodies </a> </div> </div> <div class="links-ab to-show-links-in-sm"> <div class="container"> <div class="link-container"> <a class="link-antibody" href="/order/genome-database/dataSheetPdf?producttype=antibody&productsubtype=antibody_primary&productId=15-0112-82&version=Local" target="_blank" rel="nofollow"> <span> <svg class="svg-icon data-sheet-icon"> <use href="#icon-data-sheet"></use> </svg> </span> Datasheet </a> </div> <div class="link-container"> <a href="https://www.thermofisher.com/global/en/home/life-science/antibodies/antibodies-learning-center/antibody-protocols.html?icid=antibody-pdp-protocols" target="_blank" class="link-antibody"> <span> <svg class="svg-icon protocols-icon"> <use href="#icon-protocols"></use> </svg> </span> Protocols </a> </div> <div class="link-container"> <a href="/us/en/home/technical-resources/contact-us.15-0112-82.html?supportType=TS" class="link-antibody"> <span> <svg class="svg-icon tech-support-icon"> <use href="#icon-tech-support"></use> </svg> </span> Tech Support </a> </div> </div> </div> <div class="cmrc-card-cnt" id="antibody_primary"> <div class="price-card-alignmnet" tf-product-order> <aside class="sidecard"> <div ng-switch on="$productOrderCtrl.isMultiPack()"> <div ng-switch-when="true"> <div ng-include="$productOrderCtrl.getTemplatePath()+'product-order-multipack.template.html'"></div> </div> <div ng-switch-default> <div ng-include="$productOrderCtrl.getTemplatePath()+'product-order-singlepack.template.html'"></div> </div> </div> </aside> </div> </div> </div> <div id="createCitationModal" class="modal fade citation-modal" role="dialog" aria-labelledby="createCitationModal-title">  <div class="modal-content" role="document"> <div class="modal-header"> <button type="button" class="close" data-dismiss="modal">×</button> <h4 class="modal-title" id="createCitationModal-title">Cite CD11b Monoclonal Antibody (M1/70), PE-Cyanine5, eBioscience™</h4> </div> <div class="modal-body"> <textarea id="citationTextArea" rows="5">The following product was used in this experiment: CD11b Monoclonal Antibody (M1/70), PE-Cyanine5, eBioscience™ from Thermo Fisher Scientific, catalog # 15-0112-82, RRID AB_468714.</textarea> </div> <div class="modal-footer">  <button type="button" class="well-red btn btn-danger pull-left" data-dismiss="modal" onclick="copyToClipboard();" > Click to Copy </button>  </div> </div> </div> <script type="application/ld+json"> { "@context": "https://schema.org/", "@type": "BreadcrumbList", "itemListElement": [{ "@type": "ListItem", "position": 1, "name": "Home", "item":"https://www.thermofisher.com" },{ "@type": "ListItem", "position": 2, "name": "Antibodies", "item": "https://www.thermofisher.com/us/en/home/life-science/antibodies.html" },{ "@type": "ListItem", "position": 3, "name": "CD11b", "item": "https://www.thermofisher.com/antibody/primary/target/cd11b" }] } </script> </div> <div class="links-ab to-hide-links-in-sm"> <div class="container"> <div class="link-container"> <a class="link-antibody" href="/order/genome-database/dataSheetPdf?producttype=antibody&productsubtype=antibody_primary&productId=15-0112-82&version=Local" target="_blank" rel="nofollow"> <span> <svg class="svg-icon data-sheet-icon"> <use href="#icon-data-sheet"></use> </svg> </span> Datasheet </a> </div> <div class="link-container"> <a href="https://www.thermofisher.com/global/en/home/life-science/antibodies/antibodies-learning-center/antibody-protocols.html?icid=antibody-pdp-protocols" target="_blank" class="link-antibody"> <span> <svg class="svg-icon protocols-icon"> <use href="#icon-protocols"></use> </svg> </span> Protocols </a> </div> <div class="link-container"> <a href="/us/en/home/technical-resources/contact-us.15-0112-82.html?supportType=TS" class="link-antibody"> <span> <svg class="svg-icon tech-support-icon"> <use href="#icon-tech-support"></use> </svg> </span> Tech Support </a> </div> </div> </div> <div id="image-gallery" class="scrollClass image-gallery-loading-height" ng-class="{'is-loaded':$ctrl.isLoaded}"> <div id="tabName" tab-name-value="changeTabValue"></div> <div id="originalProductLink" product-link-value="originalProductLinkValue"></div> <div class="gal-cntr container" tfs-media-gallery sku="'15-0112-82'" media-items="{'Antibody Testing Data':[{'sku':'15-0112-82','imageId':'90781','imageUrl':'https://www.thermofisher.com/antibody/images/650/15-0112-82_CD11b_Flow_1-20170119083539.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/15-0112-82_CD11b_Flow_1-20170119083539.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/15-0112-82_CD11b_Flow_1-20170119083539.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/15-0112-82_CD11b_Flow_1-20170119083539.jpg?time\u003d20240507','sortOrder':'1','description':'Staining of mouse bone marrow cells with 0.06 µg of Rat IgG2b K Isotype Control PE-Cyanine5 (Product # 15-4031-82) (blue histogram) or 0.06 µg of Anti-Mouse CD11b PE-Cyanine5 (purple histogram).Cells in the large scatter population were used for analysis.','shortDescription':'Staining of mouse bone marrow cells with 0.06 µg of Rat IgG2b K Isotype Control PE-Cyanine5 (Product # 15-4031-82) (blue histogram) or 0.06 µg of Anti-Mouse CD11b PE-Cyanine5 (purple histogram).Cells in the large scatter population were used for analysis.','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','appName':'Flow Cytometry','type':'Antibody Testing Data','journalText':'','sourceType':'1','benchsci':false,'imageName':'15-0112-82_CD11b_Flow_1-20170119083539.jpg','benchSciPubmedId':'0'}],'Published Figures':[{'sku':'15-0112-82','imageId':'1111088','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_29097_gr3.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_29097_gr3.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_29097_gr3.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_29097_gr3.jpg?time\u003d20240507','sortOrder':'2','description':'Effects of ACSL4 deficiency on PQ-induced lung inflammation. (A) mRNA expression levels of inflammatory cytokines (IL-6 and IL-1beta), COX-2, GPx4, and chemokines (CXCL1, CXCL2, CXCL5, and CXCR2) in lung tissues of untreated or PQ-administered WT (blue columns) and ACSL4-KO mice (red columns); n \u003d 4/group. * p \u003c 0.05 and ** p \u003c 0.01, untreated WT vs PQ-administered WT mice; # p \u003c 0.05 and ## p \u003c 0.01, PQ-administered WT vs ACSL4 KO mice. (B) Representative Gr-1 staining images of lung tissue of untreated or PQ-administered WT and ACSL4-KO mice. The scale bars represent 100 mum. (C) Flow cytometry analysis of CD11b + Ly6G/6C + neutrophils (upper) and CD11 + F4/80+ macrophages (lower) in the BAL fluid cells of untreated or PQ-administered WT and ACSL4-KO mice; cell samples were pooled from 5 mice per group. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.) Fig. 3','shortDescription':'Effects of ACSL4 deficiency on PQ-induced lung inflammation. (A) mRNA expression levels of inflammatory cytokines (IL-6 and IL-1beta), COX-2, GPx4, and chemokines (CXCL1, CXCL2, CXCL5, and CXCR2) in lung tissues of untreated or PQ-administered WT (blue columns) and ACSL4-KO mice (red columns); n \u003d 4/group. * p \u003c 0.05 and ** p \u003c 0.01, untreated WT vs PQ-administered WT mice; # p \u003c 0.05 and ## p \u003c 0.01, PQ-ad... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Oct 1, 2023, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Redox biology','journalText':'Redox biology 2023 - ','sourceType':'3','benchsci':true,'imageName':'tfs_29097_gr3.jpg','benchSciPubmedId':'37586249'},{'sku':'15-0112-82','imageId':'1017991','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_24742_biology-11-01609-g004.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_24742_biology-11-01609-g004.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_24742_biology-11-01609-g004.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_24742_biology-11-01609-g004.jpg?time\u003d20240507','sortOrder':'3','description':'Figure 4 TIM3-positive macrophages were recruited to ATC xenograft tumors. ( A ) I. Upper panel: TIM3 mRNA expression in RAW264.7 cells and in ATC xenografts. Total RNA was isolated, and the mRNA expression of TIM3 was examined by RT-PCR analysis. Lane 1, RAW264.7 cells; lanes 2-4, 8505C xenograft tumors ( n \u003d 3); lanes 5-7, C643 xenograft tumors ( n \u003d 3). The lower panel represents the expression of actin. II. TIM3 mRNA expression was normalized by beta-actin. Densitometry analysis of TIM3 is shown. Representative results of 3 independent experiments. ( B - D ) 20X and 63X images of 5 um thick 8505C xenograft tumor sections immunostained with TIM3-PE antibody (red). Nuclei were counterstained with DAPI. Representative immunofluorescence images of 3 independent experiments. ( E - G ) Representative FACS analysis of 2 independent experiments of macrophages (CD11b + F4/80 + TIM3 + ) out of all CD45 + cells in the 8505c xenograft tumors ( E ) and C643 xenograft tumors ( F ). ( G ) Quantification of the percentage of TIM3 + cells ( n \u003d 6-8).','shortDescription':'Figure 4 TIM3-positive macrophages were recruited to ATC xenograft tumors. ( A ) I. Upper panel: TIM3 mRNA expression in RAW264.7 cells and in ATC xenografts. Total RNA was isolated, and the mRNA expression of TIM3 was examined by RT-PCR analysis. Lane 1, RAW264.7 cells; lanes 2-4, 8505C xenograft tumors ( n \u003d 3); lanes 5-7, C643 xenograft tumors ( n \u003d 3). The lower panel represents the expression of actin.... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Nov 3, 2022, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Biology','journalText':'Biology 2022 - ','sourceType':'3','benchsci':true,'imageName':'tfs_24742_biology-11-01609-g004.jpg','benchSciPubmedId':'36358310'},{'sku':'15-0112-82','imageId':'1018040','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_24742_biology-11-01609-g003.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_24742_biology-11-01609-g003.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_24742_biology-11-01609-g003.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_24742_biology-11-01609-g003.jpg?time\u003d20240507','sortOrder':'4','description':'Figure 3 M2-like macrophages were recruited to ATC xenograft tumors. ( A , B ) Representative FACS analysis of macrophages (CD11b + F4/80 + ) out of all CD45 + cells infiltrating 8505C xenograft tumors ( A ) and C643 xenograft tumors ( B ). ( C ) Quantification of the percentage of CD11b + F4/80 + cells ( n \u003d 8-10). ( D , F ) Representative FACS analysis of M2-macrophages (CD11b + F4/80 + CD206 + ) out of all CD45 + cells infiltrating 8505C xenograft tumors ( D ) and C643 xenograft tumors ( E ). ( F ) Quantification of the percentage of CD11b + F4/80 + CD206 + cells ( n \u003d 3-5). ( G , H ) Representative histograms of Arg1 ( G ) and iNOS ( H ) expression in CD206 low/int (blue histograms) and CD206 high (pink histograms) populations in total cells from C643 xenograft tumors. ( I ) Mean fluorescence intensity (MFI) of Arg1/iNOS ratio in the CD206 high group and in the CD206 low/int group ( n \u003d 8-10). Data are expressed as mean +- SEM of 3 independent experiments. ** p \u003c 0.005.','shortDescription':'Figure 3 M2-like macrophages were recruited to ATC xenograft tumors. ( A , B ) Representative FACS analysis of macrophages (CD11b + F4/80 + ) out of all CD45 + cells infiltrating 8505C xenograft tumors ( A ) and C643 xenograft tumors ( B ). ( C ) Quantification of the percentage of CD11b + F4/80 + cells ( n \u003d 8-10). ( D , F ) Representative FACS analysis of M2-macrophages (CD11b + F4/80 + CD206 + ) out of a... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Nov 3, 2022, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Biology','journalText':'Biology 2022 - ','sourceType':'3','benchsci':true,'imageName':'tfs_24742_biology-11-01609-g003.jpg','benchSciPubmedId':'36358310'},{'sku':'15-0112-82','imageId':'1139536','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_29101_gr8.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_29101_gr8.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_29101_gr8.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_29101_gr8.jpg?time\u003d20240507','sortOrder':'5','description':'Adrenergic signaling regulates CD11b expression in myeloid cells and controls migration into the liver after alphaGC treatment (A-E) C57BL/6J WT and Adra2ac -/- mice were treated with alphaGC (2mug/animal), and liver leukocytes were analyzed by flow cytometry after 3 h. Graphs represent the total number of liver leukocytes (CD45 +) (A), neutrophils (CD11b + Ly6G +) (B) and CD11b + F4/80 + cells (C), as well as the CD11b MFI in neutrophils (D) and CD11b + F4/80 + cells (E). (F-J) C57BL6/J WT animals were pre-treated with Yoh (5 mg/kg) or Phe (10 mg/kg) and then treated with alphaGC (2mug/animal). Liver leukocytes were analyzed by flow cytometry after 3 h, and graphs represent the total number of liver leukocytes (CD45 +) (F), neutrophils (CD11b + Ly6G +) (G) and CD11b + F4/80 + cells (H), as well as the CD11b MFI in neutrophils (I) and CD11b + F4/80 + cells (J). Data represent the mean +- SD from a single set of two independent experiments (n \u003d 5). *p \u003c 0.05, **p \u003c 0.01, ***p \u003c 0.001, ****p \u003c 0.0001.','shortDescription':'Adrenergic signaling regulates CD11b expression in myeloid cells and controls migration into the liver after alphaGC treatment (A-E) C57BL/6J WT and Adra2ac -/- mice were treated with alphaGC (2mug/animal), and liver leukocytes were analyzed by flow cytometry after 3 h. Graphs represent the total number of liver leukocytes (CD45 +) (A), neutrophils (CD11b + Ly6G +) (B) and CD11b + F4/80 + cells (C), as well... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Oct 20, 2023, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'iScience','journalText':'iScience 2023 - ','sourceType':'3','benchsci':true,'imageName':'tfs_29101_gr8.jpg','benchSciPubmedId':'37841583'},{'sku':'15-0112-82','imageId':'1139534','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_29102_41467_2023_42182_Fig4_HTML.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_29102_41467_2023_42182_Fig4_HTML.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_29102_41467_2023_42182_Fig4_HTML.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_29102_41467_2023_42182_Fig4_HTML.jpg?time\u003d20240507','sortOrder':'6','description':'Terminal maturation of NK cells is associated with the downregulation of Eomes. a - c Newborn C57BL/6 mice were intraperitoneally infected with 200 PFU of MCMV or mock-infected 24-36 h after birth. a On day 21 after infection, expression of Eomes and T-bet was determined by flow cytometry. b Eomes expression was analyzed on CD27 + CD11b - , CD27 - CD11b + , KLRG1 + and KLRG1 - NK cells from MCMV and mock-infected mice, representative histograms are shown. c Quantification of Eomes expressing CD27 + CD11b - , CD27 - CD11b + , KLRG1 + and KLRG1 - NK cells ( n \u003d 9 mice per group, Mann-Whitney two-tailed test). Mean values +- SD are shown. d Newborn BALB/c and 129/SvJ mice were intraperitoneally infected with 200 PFU of MCMV or mock-infected 24-36 h after birth. On day 21 after infection, mice were euthanized and the frequency of terminally differentiated, KLRG1 and Eomes expressing splenic NK cells was determined ( n \u003d 4 Mock BALB/C, n \u003d 5 MCMV BALB/C, n \u003d 6 Mock 129/SvJ, n \u003d 3 MCMV 129/SvJ, Mann-Whitney two-tailed test). Mean values +- SD are shown. e Newborn C57BL/6 mice were intraperitoneally infected with 200 PFU of MCMV or mock-infected 24-36 h after birth. On days 60 and 90 after infection, mice were euthanized and the expression of KLRG1 and Eomes on NK cells was analyzed ( n \u003d 3 Mock 60 d.p.i., n \u003d 4 MCMV 60 d.p.i., n \u003d 4 Mock 90 d.p.i., n \u003d 6 MCMV 90 d.p.i., Mann-Whitney two-tailed test). Mean values +- SD are shown. f - h Adult C56BL/6 mice were infected with 2 x 10 5','shortDescription':'Terminal maturation of NK cells is associated with the downregulation of Eomes. a - c Newborn C57BL/6 mice were intraperitoneally infected with 200 PFU of MCMV or mock-infected 24-36 h after birth. a On day 21 after infection, expression of Eomes and T-bet was determined by flow cytometry. b Eomes expression was analyzed on CD27 + CD11b - , CD27 - CD11b + , KLRG1 + and KLRG1 - NK cells from MCMV and mock-in... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Oct 12, 2023, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Nature communications','journalText':'Nature communications 2023 - ','sourceType':'3','benchsci':true,'imageName':'tfs_29102_41467_2023_42182_Fig4_HTML.jpg','benchSciPubmedId':'37828009'},{'sku':'15-0112-82','imageId':'1139535','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_29102_41467_2023_42182_Fig6_HTML.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_29102_41467_2023_42182_Fig6_HTML.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_29102_41467_2023_42182_Fig6_HTML.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_29102_41467_2023_42182_Fig6_HTML.jpg?time\u003d20240507','sortOrder':'7','description':'Conventional NK cells downregulate Eomes upon perinatal MCMV infection. Newborn mice were intraperitoneally infected with 200 PFU of MCMV or mock-infected 24-36 h after birth. a, b On day 21 post-infection of C56BL/6 mice, spleens and livers were harvested. a Expression of CD49b and CD49a was analyzed on NK1.1 + cells, N \u003d 2. b Expression of CD27, CD11b and KLRG1 by ILC1s (CD49b - CD49a + ) was determined by flow cytometry in the liver, N \u003d 2. c On day 21 post-infection of Ncr1 iCre Eomes f/f (KO) or Eomes f/f mice (WT), CD27, CD11b and KLRG1 expression by splenic NK1.1 + cells were determined by flow cytometry. Numbers of terminally differentiated and KLRG1 expressing NK1.1 + cells are shown ( n \u003d 8 WT, n \u003d 6 KO, Mann-Whitney two-tailed test). Mean values +- SD are shown. d On day 21 post-infection of C56BL/6 mice, spleens and bone marrow were harvested. Representative histograms of Eomes expression by NK cells is shown ( N \u003d 3). Statistically significant differences are indicated ( P values). Source data are provided as a Source Data file.','shortDescription':'Conventional NK cells downregulate Eomes upon perinatal MCMV infection. Newborn mice were intraperitoneally infected with 200 PFU of MCMV or mock-infected 24-36 h after birth. a, b On day 21 post-infection of C56BL/6 mice, spleens and livers were harvested. a Expression of CD49b and CD49a was analyzed on NK1.1 + cells, N \u003d 2. b Expression of CD27, CD11b and KLRG1 by ILC1s (CD49b - CD49a + ) was determined b... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Oct 12, 2023, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Nature communications','journalText':'Nature communications 2023 - ','sourceType':'3','benchsci':true,'imageName':'tfs_29102_41467_2023_42182_Fig6_HTML.jpg','benchSciPubmedId':'37828009'},{'sku':'15-0112-82','imageId':'1139533','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_29100_IJN-18-5495-g0006.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_29100_IJN-18-5495-g0006.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_29100_IJN-18-5495-g0006.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_29100_IJN-18-5495-g0006.jpg?time\u003d20240507','sortOrder':'8','description':'Intranasal delivery of EVs in the hydrogel inhibited inflammation. ( A ) Representative flow cytometry plots showing Ly6C high monocyte and Ly6C low monocytes/macrophages (CD45 + CD11b + ) in peripheral blood. and quantification of monocytes/macrophages (Ly6C high or low ) in peripheral blood. (n\u003d5) ( B and C ). ( D ) Representative flow cytometry plots showing neutrophils (CD45 + CD11b + Ly6G + ) in peripheral blood and quantification of neutrophils in peripheral blood. n\u003d5. ( E ). ( F ) Representative images of ventricles staining CD68 (green) showing the infiltration status of macrophages and quantification of CD68 + Cells. (n\u003d5) ( G ). ELISA analysis of inflammatory factors IL-1 ( H ), IL-6 ( I ) and TNF-alpha ( J ) in peripheral blood. (n\u003d5). (*P \u003c 0.05, **P \u003c 0.01, ***P \u003c 0.001). Abbreviation : ns, not significant.','shortDescription':'Intranasal delivery of EVs in the hydrogel inhibited inflammation. ( A ) Representative flow cytometry plots showing Ly6C high monocyte and Ly6C low monocytes/macrophages (CD45 + CD11b + ) in peripheral blood. and quantification of monocytes/macrophages (Ly6C high or low ) in peripheral blood. (n\u003d5) ( B and C ). ( D ) Representative flow cytometry plots showing neutrophils (CD45 + CD11b + Ly6G + ) in periph... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Oct 5, 2023, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'International journal of nanomedicine','journalText':'International journal of nanomedicine 2023 - ','sourceType':'3','benchsci':true,'imageName':'tfs_29100_IJN-18-5495-g0006.jpg','benchSciPubmedId':'37791323'},{'sku':'15-0112-82','imageId':'1139532','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_29099_fimmu-14-1230681-g003.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_29099_fimmu-14-1230681-g003.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_29099_fimmu-14-1230681-g003.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_29099_fimmu-14-1230681-g003.jpg?time\u003d20240507','sortOrder':'9','description':'Figure 3 P. anaerobius promoted oxaliplatin resistance by recruiting MDSCs into the CRC microenvironment. (A) Viability of MC-38 cells co-cultured with P. anaerobius or in conditioned medium supplemented with PA supernatant (CCK-8 assay, p \u003e 0.05, PA indicated by red arrow). (B) MDSCs (Gr-1 + CD11B + ) from bone marrow of CRC mice detected by multicolor flow cytometry. (C, D) MDSCs infiltrated into the tumor microenvironment detected by fluorescein isothiocyanate (FITC) with anti-mouse CD11b antibody (green), allophycocyanin (APC), anti-mouse Gr-1 antibody (red), and DAPI (blue). (E) Morphological feature of MDSCs collected by FCM (Giemsa staining, purple-blue leaf-shaped or round-type nucleus and almost colorless cytoplasm). (F) Chemotaxis ability of MDSCs treated with PA -CM, MC-38-CM, and PA +MC-38-CM (co-culture medium of PA and MC-38), respectively. (A-F) Data were presented as mean +- SD, p- values were determined by one-way analysis of variance. Three independent experiments were performed with consistent results.','shortDescription':'Figure 3 P. anaerobius promoted oxaliplatin resistance by recruiting MDSCs into the CRC microenvironment. (A) Viability of MC-38 cells co-cultured with P. anaerobius or in conditioned medium supplemented with PA supernatant (CCK-8 assay, p \u003e 0.05, PA indicated by red arrow). (B) MDSCs (Gr-1 + CD11B + ) from bone marrow of CRC mice detected by multicolor flow cytometry. (C, D) MDSCs infiltrated into the tumo... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Oct 3, 2023, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Frontiers in immunology','journalText':'Frontiers in immunology 2023 - ','sourceType':'3','benchsci':true,'imageName':'tfs_29099_fimmu-14-1230681-g003.jpg','benchSciPubmedId':'37781363'},{'sku':'15-0112-82','imageId':'1139529','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_29098_fimmu-14-1147695-g001.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_29098_fimmu-14-1147695-g001.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_29098_fimmu-14-1147695-g001.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_29098_fimmu-14-1147695-g001.jpg?time\u003d20240507','sortOrder':'10','description':'Gastric G-MDSCs are characterized by a specific transcriptional signature and can be identified by calprotectin (S100a8 and/or S100a9) expression. (A) Representative FACS plots of gastric MDSC versus non-MDSC myeloid cell populations using CD11b and Ly6G cell-surface protein markers, of dissociated gastric cells from uninfected versus 6mo H felis -infected WT mouse stomachs. Red font \'\'1\'\' annotates gastric non-myeloid and Ly6G-negative cells. Green font \'\'2\'\' annotates CD11b + Ly6G - non-G-MDSC myeloid cells. Black font \'\'3\'\' annotates gastric CD11b + Ly6G + G-MDSC myeloid cells. Blue font \'\'4\'\' annotates gastric CD11b - Ly6G + non-myeloid cells. (B) Microarray heatmap showing the highest expressed genes that are specifically enriched in gastric CD11b + Ly6G - non-G-MDSC myeloid cells (annotated as green font \'\'2\'\'), versus those specifically enriched in gastric CD11b + Ly6G + G-MDSC myeloid cells (annotated as black font \'\'3\'\'), and those specifically enriched in non-myeloid gastric CD11b - Ly6G + control cells (annotated as blue font \'\'4\'\'). The gene names for the calprotectin subunits S100a8 and S100a9, Il1b, Slfn4, and Cxcr2 are listed (S100a8 and Cxcr2 are annotated in red font because they will later be used in the study for Cre/Flox generation). (C) Representative image of the immunohistochemical staining of calprotectin (brown) in 6mo H felis -infected mouse gastric mucosa relative to uninfected.','shortDescription':'Gastric G-MDSCs are characterized by a specific transcriptional signature and can be identified by calprotectin (S100a8 and/or S100a9) expression. (A) Representative FACS plots of gastric MDSC versus non-MDSC myeloid cell populations using CD11b and Ly6G cell-surface protein markers, of dissociated gastric cells from uninfected versus 6mo H felis -infected WT mouse stomachs. Red font \'\'1\'\' annotates gastric... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Sep 29, 2023, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Frontiers in immunology','journalText':'Frontiers in immunology 2023 - ','sourceType':'3','benchsci':true,'imageName':'tfs_29098_fimmu-14-1147695-g001.jpg','benchSciPubmedId':'37744359'},{'sku':'15-0112-82','imageId':'1139531','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_29098_fimmu-14-1147695-g006.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_29098_fimmu-14-1147695-g006.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_29098_fimmu-14-1147695-g006.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_29098_fimmu-14-1147695-g006.jpg?time\u003d20240507','sortOrder':'11','description':'Cxcr2-deficient S100a8-expressing cells exhibit an altered expression of several genes associated with lipid metabolism, and an increase in the production of the lipid peroxidation product, 4-hydroxynonenal (4-HNE), within gastric epithelial lesions, following 6mo H felis infection. (A) Representative FACS plots of CD11b + Ly6G + G-MDSCs from H felis -infected S100a8 Cre/+ Cxcr2 flox/flox versus Cxcr2 flox/flox stomachs, which were used for sorting gastric G-MDSCs for microarray analyses. (B) Microarray heatmap of the MDSC-specific genes that exhibited altered expression patterns in G-MDSCs in response to Cre/Flox-mediated Cxcr2 ablation. Fabp5 is directly involved in lipid peroxidation and is annotated by a red arrow. (C) Immunohistochemical staining of 4-HNE staining (brown), within gastric epithelial lesions, in 6mo H felis -infected S100a8 Cre/+ Cxcr2 flox/flox versus Cxcr2 flox/flox stomachs. (D) Quantitative morphometry of 4-HNE staining. (E) Representative immunohistochemical staining of calprotectin (brown) in 6mo H felis -infected S100a8 Cre/+ Cxcr2 flox/flox versus Cxcr2 flox/flox stomachs. **P \u003c 0.01.','shortDescription':'Cxcr2-deficient S100a8-expressing cells exhibit an altered expression of several genes associated with lipid metabolism, and an increase in the production of the lipid peroxidation product, 4-hydroxynonenal (4-HNE), within gastric epithelial lesions, following 6mo H felis infection. (A) Representative FACS plots of CD11b + Ly6G + G-MDSCs from H felis -infected S100a8 Cre/+ Cxcr2 flox/flox versus Cxcr2 flox/... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Sep 29, 2023, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Frontiers in immunology','journalText':'Frontiers in immunology 2023 - ','sourceType':'3','benchsci':true,'imageName':'tfs_29098_fimmu-14-1147695-g006.jpg','benchSciPubmedId':'37744359'},{'sku':'15-0112-82','imageId':'1139530','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_29098_fimmu-14-1147695-g002.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_29098_fimmu-14-1147695-g002.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_29098_fimmu-14-1147695-g002.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_29098_fimmu-14-1147695-g002.jpg?time\u003d20240507','sortOrder':'12','description':'Figure 2 S100a8 and S100a9 are enriched in gastric G-MDSCs but not in acutely recruited gut neutrophils. (A) Representative FACS plots of gastric G-MDSCs versus cecal neutrophils in 6-month H felis -infected stomachs versus 2-day C difficile infected ceca respectively. (B) Microarray heatmap showing the highest expressed genes that are specifically enriched in gastric CD11b + Ly6G + G-MDSCs relative to CD11b + Ly6G + cecal neutrophils in 6-month H felis -infected stomachs versus 2-day C difficile infected ceca respectively. The black arrows annotate the genes that are highly expressed in G-MDSCs of 6 month H felis -infected stomachs but not in neutrophils of 2-day C difficile infected ceca.','shortDescription':'Figure 2 S100a8 and S100a9 are enriched in gastric G-MDSCs but not in acutely recruited gut neutrophils. (A) Representative FACS plots of gastric G-MDSCs versus cecal neutrophils in 6-month H felis -infected stomachs versus 2-day C difficile infected ceca respectively. (B) Microarray heatmap showing the highest expressed genes that are specifically enriched in gastric CD11b + Ly6G + G-MDSCs relative to CD11... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Sep 29, 2023, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Frontiers in immunology','journalText':'Frontiers in immunology 2023 - ','sourceType':'3','benchsci':true,'imageName':'tfs_29098_fimmu-14-1147695-g002.jpg','benchSciPubmedId':'37744359'},{'sku':'15-0112-82','imageId':'1139528','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_29079_urn-x-wiley-0260437X-media-jat4496-jat4496-fig-0002.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_29079_urn-x-wiley-0260437X-media-jat4496-jat4496-fig-0002.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_29079_urn-x-wiley-0260437X-media-jat4496-jat4496-fig-0002.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_29079_urn-x-wiley-0260437X-media-jat4496-jat4496-fig-0002.jpg?time\u003d20240507','sortOrder':'13','description':'2 FIGURE Flow cytometric analysis of peritoneal macrophages using CD11b-PerCPCy5.5, CD86-PE, and CD206-FITC antibodies after single or dual blocking of toll-like receptor 4 (TLR4) and tumor necrosis factor receptor 1 (TNFR1) and posttreatment with recombinant interleukin 10 (IL-10). Dot plot images of M1/M2 macrophage population analysis. Graphical representation of the CD86 + M1 population and graphical representation of the CD206 + M2 population in 11 different groups were shown. Data were represented as mean +- SD from three independent experiments. \'\'*\'\' indicates a significant difference in comparison with control in the non-IL-10-treated groups, \'\'#\'\' indicates a significant difference in comparison with lipopolysaccharide (LPS), \'\'*\'\' indicates a significant difference with respect to LPS + DEX, \'\'^\'\' indicates a significant difference with respect to TLR4Ab + LPS, \'\'EUR\'\' indicates significant difference with respect to TNFR1Ab + LPS, \'\'epsilon\'\' indicates significant difference with respect to control in the IL-10-treated group, \'\'delta\'\' indicates a significant difference in comparison with LPS + IL-10, \'\'$\'\' indicates significant difference with respect to LPS + DEX + IL-10, \'\'alpha\'\' indicates significant difference with respect to TLR4Ab + LPS + IL-10, and \'\'U\'\' indicates significant difference with respect to TNFR1Ab + LPS + IL-10. All the differences were statistically significant at p \u003c 0.05 level.','shortDescription':'2 FIGURE Flow cytometric analysis of peritoneal macrophages using CD11b-PerCPCy5.5, CD86-PE, and CD206-FITC antibodies after single or dual blocking of toll-like receptor 4 (TLR4) and tumor necrosis factor receptor 1 (TNFR1) and posttreatment with recombinant interleukin 10 (IL-10). Dot plot images of M1/M2 macrophage population analysis. Graphical representation of the CD86 + M1 population and graphical re... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Oct 1, 2023, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Journal of applied toxicology : JAT','journalText':'Journal of applied toxicology : JAT 2023 - ','sourceType':'3','benchsci':true,'imageName':'tfs_29079_urn-x-wiley-0260437X-media-jat4496-jat4496-fig-0002.jpg','benchSciPubmedId':'37177863'},{'sku':'15-0112-82','imageId':'1019346','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_24743_fphar-13-1095757-g002.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_24743_fphar-13-1095757-g002.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_24743_fphar-13-1095757-g002.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_24743_fphar-13-1095757-g002.jpg?time\u003d20240507','sortOrder':'14','description':'FIGURE 2 Alteration of cellular composition in the diseased status of mice and humans. (A,B) Fractions of major cells types in aneurysmal aorta vs. the corresponding normal aorta of humans (A) and mice (B) . (C) Immunofluorescence analysis for SMMHC (red), alphaSMA (green), and overlays with DAPI-labeled nuclei (blue) showing smooth muscle cells in the human vascular media (scale bars: 100 mum). Lu means the lumen side of the vascular wall, and A means the adventitia side of the vascular wall. (D,E) Immunofluorescence analysis for vimentin (white) (D) and CD45 (purple) (E) and overlays with DAPI-labeled nuclei (blue) showing fibroblasts and immune cells in the human aorta (scale bars: 100 mum). (F) Immunostaining for calponin (red), alphaSMA (green), and overlays with DAPI-labeled nuclei (blue) showing smooth muscle cells in the mouse aortic media (scale bars: 100 mum). (G) Immunostaining for vimentin (white) and DAPI overlay in the thoracic and abdominal aorta form mice subjected to 4 weeks of Ang II induction (scale bars: 500 mum). (H) Immunostaining for CD45 (red), CD68 (green), and overlays with DAPI-labeled nuclei (blue) showing macrophages in the mouse aorta (scale bars: 100 mum). (I) Flow cytometry of the proportion of macrophages (F4/80 + CD11B + ), monocytes (LY6C + CD11B + ), and T cells (CD3 + ) in CD45 + immune cells among three groups (n \u003d 3-4, per group).','shortDescription':'FIGURE 2 Alteration of cellular composition in the diseased status of mice and humans. (A,B) Fractions of major cells types in aneurysmal aorta vs. the corresponding normal aorta of humans (A) and mice (B) . (C) Immunofluorescence analysis for SMMHC (red), alphaSMA (green), and overlays with DAPI-labeled nuclei (blue) showing smooth muscle cells in the human vascular media (scale bars: 100 mum). Lu means th... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Feb 2, 2023, 5:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Frontiers in pharmacology','journalText':'Frontiers in pharmacology 2023 - ','sourceType':'3','benchsci':true,'imageName':'tfs_24743_fphar-13-1095757-g002.jpg','benchSciPubmedId':'36703732'},{'sku':'15-0112-82','imageId':'1019326','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_24741_12276_2022_851_Fig3_HTML.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_24741_12276_2022_851_Fig3_HTML.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_24741_12276_2022_851_Fig3_HTML.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_24741_12276_2022_851_Fig3_HTML.jpg?time\u003d20240507','sortOrder':'15','description':'Deletion of Cxxc5 ameliorates NASH progression. a - m Cxxc5 +/+ and Cxxc5 -/- mice were fed a HFD for 12 weeks and injected with CCl 4 twice a week for the final 4 weeks to induce NASH ( n \u003d 7 per group). a Representative IHC images of F4/80- and Cd11b-stained liver tissues (left panel). Quantification of hCLS formation and F4/80- and Cd11b-positive areas (right panel). Scale bars, 100 um. b Flow cytometry analyses of the expression of F4/80 and Cd11b (left panel). Percentage of F4/80 + Cd11b + cells ( n \u003d 3) (right panel). c Inflammation score. d Relative mRNA expression levels of genes involved in pro-inflammation ( n \u003d 3). e The NAFLD score. f Representative images of DHE-stained cells (left panel). Quantification of ROS formation by measuring DHE-positive cells in liver tissues (right panel). Scale bar, 100 um. g TUNEL staining of the liver (top panel). Quantification of TUNEL-positive cells (bottom panel). Scale bar, 100 um. h Relative mRNA expression of genes involved in cell death pathways (n \u003d 3). i Representative IHC images for alpha-Sma, collagen I, desmin, and Sirius red staining of liver tissues. Scale bars, 100 um. j Relative mRNA expression of genes involved in fibrogenesis ( n \u003d 3). k The fibrosis score. l , m Plasma concentrations of FFAs ( l ), AST and ALT ( m ). Data represent the mean +- SD. * P \u003c 0.05; ** P \u003c 0.01; *** P \u003c 0.001 determined by Student\u0026apos;s t test.','shortDescription':'Deletion of Cxxc5 ameliorates NASH progression. a - m Cxxc5 +/+ and Cxxc5 -/- mice were fed a HFD for 12 weeks and injected with CCl 4 twice a week for the final 4 weeks to induce NASH ( n \u003d 7 per group). a Representative IHC images of F4/80- and Cd11b-stained liver tissues (left panel). Quantification of hCLS formation and F4/80- and Cd11b-positive areas (right panel). Scale bars, 100 um. b Flow cytometry ... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Sep 1, 2022, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Experimental \u0026 molecular medicine','journalText':'Experimental \u0026 molecular medicine 2022 - ','sourceType':'3','benchsci':true,'imageName':'tfs_24741_12276_2022_851_Fig3_HTML.jpg','benchSciPubmedId':'36114279'},{'sku':'15-0112-82','imageId':'1019226','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_24737_urn-x-wiley-08941491-media-glia24255-glia24255-fig-0001.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_24737_urn-x-wiley-08941491-media-glia24255-glia24255-fig-0001.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_24737_urn-x-wiley-08941491-media-glia24255-glia24255-fig-0001.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_24737_urn-x-wiley-08941491-media-glia24255-glia24255-fig-0001.jpg?time\u003d20240507','sortOrder':'16','description':'1 FIGURE Flow cytometry analysis of the CD11b+ cells. Cells isolated from non-perfused [(a)-(e)] and perfused [(f)-(j)] brains did not show significant differences. [(a), (f)] Histograms showing two CD45-expressing cell populations: CD45 low (microglia) and CD 45 high (possible macrophages). [(b), (g)] Microglia, identified as CD11b+ and CD45 low (Q3), comprised the highest proportion of cells (91.7%-94.5%), whereas a low percentage of potential macrophages (CD11b+/CD45 high, Q2) were observed. [(c), (h)] Forward scatter (FSC) analysis showing a slight smaller size of the CD45 low cells (red) respect to CD45 high (blue) cells. [(d), (i)] CD11b analysis showed a slight lower expression within CD45 low cells (red) respect to CD45 high (blue) cells. [(e), (j)] Forward scatter (FSC) and side scatter (SSC) characteristics of CD11b+/CD45 low (red) and CD11b+/CD45 high (blue) are shown','shortDescription':'1 FIGURE Flow cytometry analysis of the CD11b+ cells. Cells isolated from non-perfused [(a)-(e)] and perfused [(f)-(j)] brains did not show significant differences. [(a), (f)] Histograms showing two CD45-expressing cell populations: CD45 low (microglia) and CD 45 high (possible macrophages). [(b), (g)] Microglia, identified as CD11b+ and CD45 low (Q3), comprised the highest proportion of cells (91.7%-94.5%)... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Dec 1, 2022, 5:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Glia','journalText':'Glia 2022 - ','sourceType':'3','benchsci':true,'imageName':'tfs_24737_urn-x-wiley-08941491-media-glia24255-glia24255-fig-0001.jpg','benchSciPubmedId':'35943203'},{'sku':'15-0112-82','imageId':'952239','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_20559_41467_2022_29730_Fig4_HTML.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_20559_41467_2022_29730_Fig4_HTML.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_20559_41467_2022_29730_Fig4_HTML.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_20559_41467_2022_29730_Fig4_HTML.jpg?time\u003d20240507','sortOrder':'17','description':'Fig. 4 CAF-1 depletion induces myeloid differentiation in vivo and a mixed-lineage transcriptional signature in HSPCs. a Schematic of polyI:C (polyinosinic:polycytidylic acid) inducible Mx1-Cre/LoxP system in mice. Flow cytometric analysis of BM MNCs is performed 72 hrs post-induction of mice bearing homozygous Chaf1b floxed alleles and Mx1-Cre ( Chaf1b fl /fl ; Mx1-Cre) and littermate controls ( Chaf1b +/+ ; Mx1-Cre). b Flow cytometric analysis of myeloid differentiation markers (CD11b and Gr1) showing overlaid density plots and histograms of wild-type (Chaf1b +/+ ) and Chaf1b-deleted (Chaf1b Delta/ Delta ) BM MNCs. c Quantification of gated populations in b showing mean and standard deviation of CD11b and Gr1 double-positive and double negative % populations from live BM MNCs isolated from n \u003d 2 wild-type and n \u003d 3 knockout littermates. d Schematic of Chaf1b depletion in primary HSPCs. HSPCs isolated from homozygous floxed mice ( Chaf1b fl /fl ) are transduced with retroviral vectors, either empty control (MIGR1-CTRL) or overexpressing Cre recombinase (MIGR1-Cre) and analyzed by RNA-seq 48 h following expansion in myeloid media conditions. e RNA-seq analysis showing percentages and numbers of upregulated or downregulated genes in CAF-1 OFF iGMPs, HOXA9 OFF iGMPs, and Chaf1b Delta/ Delta HSPCs. DEGs are filtered based on fold change \u003e\u003d 1.5 and FDR \u003c 0.05. f Venn diagrams of unique and common DEGs between CAF-1 OFF iGMPs, HOXA9 OFF iGMPs, and Chaf1b Delta/ Delta HSPCs shown i','shortDescription':'Fig. 4 CAF-1 depletion induces myeloid differentiation in vivo and a mixed-lineage transcriptional signature in HSPCs. a Schematic of polyI:C (polyinosinic:polycytidylic acid) inducible Mx1-Cre/LoxP system in mice. Flow cytometric analysis of BM MNCs is performed 72 hrs post-induction of mice bearing homozygous Chaf1b floxed alleles and Mx1-Cre ( Chaf1b fl /fl ; Mx1-Cre) and littermate controls ( Chaf1b +/+... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Apr 29, 2022, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Nature communications','journalText':'Nature communications 2022 - ','sourceType':'3','benchsci':true,'imageName':'tfs_20559_41467_2022_29730_Fig4_HTML.jpg','benchSciPubmedId':'35487911'},{'sku':'15-0112-82','imageId':'952219','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_20557_gr5.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_20557_gr5.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_20557_gr5.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_20557_gr5.jpg?time\u003d20240507','sortOrder':'18','description':'The GOG stimulated BMSCs promoted the osteoclastogenesis of HSCs and the inhibited PERK pathway blocked the promotive effects of GOG on osteoblastic/osteoclastic differentiations. (a) The schematic diagram showed the designed induction procedure and scheduled detections at different timepoints. The HSCs were co-cultured with BMSCs in the transwell system for evaluation on the effects of GOG on osteoblastic and osteoclastic differentiations. The HSCs were cultured in the low chamber with 4 days of M-CSF (50 ng/mL) stimulus for inducing BMMs differentiation of HSCs. After 4 days M-CSF induction, the Flow cytometry analysis was conducted to evaluate the proportion of BMMs in total HSCs and the ALP staining was performed to evaluate the osteoblastic differentiation of BMSCs. The osteoclast differentiation medium containing 50 ng/mL M-CSF and 100 ng/mL RANKL was replaced at day 5 in the lower chamber for further analysis on osteoclastic differentiation of BMMs. In the subsequent induction of BMMs, the M1/M2 polarization was detected by M1/M2 specific markers (iNOS and arginase) immunofluorescent staining after 2 days of M-CSF + RANKL induction, and the calcium oscillation of BMMs was also detected after 2 days of M-CSF + RANKL induction. After 6 days of M-CSF + RANKL induction, the mature osteoclast differentiation from BMMs was verified by TRAP staining and the osteoblastic differentiation of BMSCs was evaluated by ARS staining. (b) The FACS analysis on the BMMs differentiation o','shortDescription':'The GOG stimulated BMSCs promoted the osteoclastogenesis of HSCs and the inhibited PERK pathway blocked the promotive effects of GOG on osteoblastic/osteoclastic differentiations. (a) The schematic diagram showed the designed induction procedure and scheduled detections at different timepoints. The HSCs were co-cultured with BMSCs in the transwell system for evaluation on the effects of GOG on osteoblastic ... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Sep 1, 2022, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Bioactive materials','journalText':'Bioactive materials 2022 - ','sourceType':'3','benchsci':true,'imageName':'tfs_20557_gr5.jpg','benchSciPubmedId':'35386350'},{'sku':'15-0112-82','imageId':'1019306','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_24740_41467_2022_29471_Fig9_HTML.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_24740_41467_2022_29471_Fig9_HTML.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_24740_41467_2022_29471_Fig9_HTML.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_24740_41467_2022_29471_Fig9_HTML.jpg?time\u003d20240507','sortOrder':'19','description':'Pharmacological inhibitor of MLCK MW01-022AZ suppressed tumor inflammation and growth. a Schematic of LLC lung tumor implantation in C57Bl6 mice and MW01-022AZ treatment. b-d Effect of MW01-022AZ on LLC b gross tumor morphology ( n \u003d tumors from 6 mice) c tumor volume ( n \u003d 9 mice and d tumor weight at endpoint (21 days) ( n \u003d 9 mice). *p \u003c 0.0001 for vehicle vs MW01-022AZ treatment, determined by t -test. e FACS profiles and f quantification of Gr1-CD11b+ ( p \u003d 0.1146) Gr1loCD11b+ (* p \u003d 0.0402), Gr1hiCD11b+ (* p \u003d 0.0146) myeloid cells in representative MW01-022AZ vs vehicle-treated tumors at endpoint (21 days) ( n \u003d 3 mice), determined by t -test. For Facs gating scheme, see Supplementary Fig. 7b . g Quantification and h representative histographs of F4/80+ macrophages ( n \u003d sections from 6 mice) *p \u003c 0.0001 for vehicle or MW01-022AZ by t -test, CD31+ blood vessels ( n \u003d sections from 7 mice) *p \u003c 0.0001 for vehicle or MW01-022AZ by t -test, CD8+ T cells ( n \u003d sections from 9 mice) *p \u003d 0.0244 for vehicle vs MW01-022AZ by Mann-Whitney test in tissues from mice treated with vehicle or MW01-022AZ . i Model of integrin activation demonstrating that cytokine stimulation activates a pathway whereby PI3Kgamma induces MLCK210 and myosin activation and colocalization with Rap1, resulting in Rap1-mediated integrin alpha4 conformation changes and interaction of the integrin with the actin cytoskeleton. Data are presented as mean values +- SEM. Statistical significance determined by','shortDescription':'Pharmacological inhibitor of MLCK MW01-022AZ suppressed tumor inflammation and growth. a Schematic of LLC lung tumor implantation in C57Bl6 mice and MW01-022AZ treatment. b-d Effect of MW01-022AZ on LLC b gross tumor morphology ( n \u003d tumors from 6 mice) c tumor volume ( n \u003d 9 mice and d tumor weight at endpoint (21 days) ( n \u003d 9 mice). *p \u003c 0.0001 for vehicle vs MW01-022AZ treatment, determined by t -test. ... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Apr 1, 2022, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Nature communications','journalText':'Nature communications 2022 - ','sourceType':'3','benchsci':true,'imageName':'tfs_24740_41467_2022_29471_Fig9_HTML.jpg','benchSciPubmedId':'35365657'},{'sku':'15-0112-82','imageId':'1019286','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_24740_41467_2022_29471_Fig7_HTML.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_24740_41467_2022_29471_Fig7_HTML.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_24740_41467_2022_29471_Fig7_HTML.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_24740_41467_2022_29471_Fig7_HTML.jpg?time\u003d20240507','sortOrder':'20','description':'Deletion of bone marrow cell MLCK210 inhibits tumor growth. a Schematic of bone marrow transplantation and tumor implantation. b Genomic PCR to detect Mlck 210 gene in peripheral blood cells from BMT transplanted mice ( n \u003d 2 mice). c - e Tumor volumes ( c ), weights at endpoint (15 days) (*p \u003c 0.0001 WT vs Mlck210 -/- BM) ( d ) and images of gross tumor morphology ( e ) from LLC tumors in WT mice transplanted with bone marrow from WT ( n \u003d 10 mice) or Mlck210 -/- mice ( n \u003d 10 mice). f Representative FACS profiles and g quantification of Gr1-CD11b+ ( p \u003d 0.9724) Gr1loCD11b+ (*p \u003d 0.0280), Gr1hiCD11b+ ( p \u003d 0.8641) myeloid cells in representative WT vs Mlck210 -/- BM transplanted tumors harvested at endpoint (15 days) ( n \u003d 3 mice). For Facs gating scheme, see Supplementary Fig. 7b . h Representative histographs and i quantification of F4/80+ macrophages/field ( n \u003d sections from 5 WT mice and 5 Mlck210 -/- ) *p \u003d 0.0009, CD31+ blood vessels/field ( n \u003d sections from 5 WT and 3 Mlck210 -/- mice) *p \u003d 0.001, CD8+ T cells/field ( n \u003d sections from 5 WT and 4 Mlck210 -/- mice) *p \u003d 0.019 in tumor sections and 100X H\u0026E-stained tumor sections to detect percent necrosis/field ( n \u003d sections from 5 mice) *p \u003d 0.0004 from mice transplanted with WT vs Mlck210 -/- bone marrow. Data are presented as mean values +- SEM. Significance testing was performed by Student\u0026apos;s t -test. Experiments were performed twice. Source data are provided with this article as a Source Data file.','shortDescription':'Deletion of bone marrow cell MLCK210 inhibits tumor growth. a Schematic of bone marrow transplantation and tumor implantation. b Genomic PCR to detect Mlck 210 gene in peripheral blood cells from BMT transplanted mice ( n \u003d 2 mice). c - e Tumor volumes ( c ), weights at endpoint (15 days) (*p \u003c 0.0001 WT vs Mlck210 -/- BM) ( d ) and images of gross tumor morphology ( e ) from LLC tumors in WT mice transplan... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Apr 1, 2022, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Nature communications','journalText':'Nature communications 2022 - ','sourceType':'3','benchsci':true,'imageName':'tfs_24740_41467_2022_29471_Fig7_HTML.jpg','benchSciPubmedId':'35365657'},{'sku':'15-0112-82','imageId':'952198','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_20556_pntd.0010224.g002.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_20556_pntd.0010224.g002.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_20556_pntd.0010224.g002.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_20556_pntd.0010224.g002.jpg?time\u003d20240507','sortOrder':'21','description':'10.1371/journal.pntd.0010224.g002 Fig 2 During LdCen -/- ID infection, neutrophil derived increased CCL3 recruits significantly higher number of dendritic cells attributed with proinflammatory phenotype in the ear dLN compared to LdWT infection. (A) Parasitized neutrophils (Cd11b + Ly6G + Ly6c int RFP/mCherry + ) were flow sorted from the ear dLN 5d post infection and mRNA expression levels of CCL3 from sorted neutrophils in the ear dLN were estimated by qPCR as described in Materials and Methods and expressed as fold change from uninfected naive mice. The experiment was repeated three times with pooled digests from five to six ear dLNs per experiment. The data represent the mean values +- SD of results from three independent experiments that all yielded similar results (n \u003d 5). ** p \u003c 0.005 between the groups. (B) The gating strategy and individual flow plots for DCs (CD11b + Ly6G - Ly6C - CD11c + MHCII hi ) recruitment in ear dLNs 5d post infection is shown under CCL3 non-depleted or depleted condition. (C ) Total number of Cd11b + cells recruited in ear dLN 5 days post infection in mice depleted or not of CCL3 has been shown. (D) Changes in the total number of DCs per ear dLN. Values shown are the mean numbers of cells per ear dLN +- SD of results. 6-8 ear dLN, pooled data from 3 independent experiments that all yielded similar results (n \u003d 6). *p\u003c 0.05; ** p \u003c 0.005, *** p \u003c 0.0005 between the groups. ( E) Parasitized DCs (CD11b + CD11c + MHCII hi RFP/mCherry + ) were flo','shortDescription':'10.1371/journal.pntd.0010224.g002 Fig 2 During LdCen -/- ID infection, neutrophil derived increased CCL3 recruits significantly higher number of dendritic cells attributed with proinflammatory phenotype in the ear dLN compared to LdWT infection. (A) Parasitized neutrophils (Cd11b + Ly6G + Ly6c int RFP/mCherry + ) were flow sorted from the ear dLN 5d post infection and mRNA expression levels of CCL3 from sor... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Feb 1, 2022, 5:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'PLoS neglected tropical diseases','journalText':'PLoS neglected tropical diseases 2022 - ','sourceType':'3','benchsci':true,'imageName':'tfs_20556_pntd.0010224.g002.jpg','benchSciPubmedId':'35192633'},{'sku':'15-0112-82','imageId':'1019266','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_19070_41467_2021_27683_Fig9_HTML.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_19070_41467_2021_27683_Fig9_HTML.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_19070_41467_2021_27683_Fig9_HTML.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_19070_41467_2021_27683_Fig9_HTML.jpg?time\u003d20240507','sortOrder':'22','description':'Fig. 9 OPN induces lysosomal-dependent lipid metabolism in BMDMs. a Representative western blots (left) and quantification (right, n \u003d 3 biologically independent samples) of OPN receptor alphav and beta3 expression in BMDMs and metabolically activated macrophages (MMes) after culture for 4 days in vitro. b Schematic diagram illustrating the co-culture system as indicated below ( c ). c , d Representative images ( c ) and quantification ( n \u003d 5 biologically independent samples) ( d ) of crystal violet staining of BMDMs (ctrl) and MMes treated with or without rOPN for 24 h in a Transwell system. Scale bar: 50 mum. e Immunofluorescence images of buoyant BMDMs (F4/80) containing lipid vesicles (Perilipin 1) isolated from bone marrow supernatant at week 12. Scale bar: 15 mum. f FACS analysis of FC + (F4/80+ and CD11b+ , top) and Perilipin1+ (bottom) BMDMs from NFD- (left) and HFD-fed (right) mice. P9, FC + and Perilipin1+ BMDM population from Q2. g Percentage of FC + and Perilipin1+ BMDMs ( n \u003d 5 biologically independent samples). h Lactate concentration in bone marrow supernatant ( n \u003d 5 biologically independent samples). i Schematic diagram illustrating the co-culture system as described below ( j ). j Immunofluorescence staining of the co-cultured BMDMs for 4 days in vitro; the eWAT from mice fed the HFD for 8 weeks was placed in the upper chamber; Neu Ab (2.0 mug/ml) was added into the lower chamber. Scale bar: 50 mum. The right-most image is an enlarged view of the field in t','shortDescription':'Fig. 9 OPN induces lysosomal-dependent lipid metabolism in BMDMs. a Representative western blots (left) and quantification (right, n \u003d 3 biologically independent samples) of OPN receptor alphav and beta3 expression in BMDMs and metabolically activated macrophages (MMes) after culture for 4 days in vitro. b Schematic diagram illustrating the co-culture system as indicated below ( c ). c , d Representative im... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Jan 20, 2022, 5:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Nature communications','journalText':'Nature communications 2022 - ','sourceType':'3','benchsci':true,'imageName':'tfs_19070_41467_2021_27683_Fig9_HTML.jpg','benchSciPubmedId':'35058428'},{'sku':'15-0112-82','imageId':'926410','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_19070_41467_2021_27683_Fig5_HTML.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_19070_41467_2021_27683_Fig5_HTML.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_19070_41467_2021_27683_Fig5_HTML.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_19070_41467_2021_27683_Fig5_HTML.jpg?time\u003d20240507','sortOrder':'23','description':'Fig. 5 OPN is primarily secreted by F4/80 + and CD11b+ macrophages in eWAT. a Representative images of immunofluorescence staining of OPN in eWAT from NFD- and HFD-fed mice at weeks 8, 12, and 16. Scale bar: 100 mum. b Quantification of the F4/80-positive or OPN-positive stained area percentage in eWAT from a ( n \u003d 4 biologically independent samples). c Relative expression of Spp1 in the adipocyte fraction (AF) and stromal vascular fraction (SVF) from eWAT or iWAT of HFD-fed mice at week 12 ( n \u003d 3 biologically independent samples). d ATMs gated by FACS for F4/80 and CD11b expression from eWAT at week 12 of NFD (left) or HFD feeding (right). Q2 represents the F4/80 + CD11b + (FC + ) ATM population, and Q3 represents the F4/80-CD11b- (FC-) ATM population. e Percentage of FC + ATMs from NFD- and HFD-fed mice at week 12 ( n \u003d 4 biologically independent samples). f Relative expression of Spp1 in FC+ and FC- ATMs from HFD-fed mice at week 12 ( n \u003d 3 biologically independent samples). Images are representative of 3 independent experiments. All data are presented as mean +- SD. Two-way ANOVA with Sidak\u0027s post-hoc test ( b ) and two-tailed Welch\u0027s t -test ( c , e , f ) were used. Source data are provided as a Source Data file.','shortDescription':'Fig. 5 OPN is primarily secreted by F4/80 + and CD11b+ macrophages in eWAT. a Representative images of immunofluorescence staining of OPN in eWAT from NFD- and HFD-fed mice at weeks 8, 12, and 16. Scale bar: 100 mum. b Quantification of the F4/80-positive or OPN-positive stained area percentage in eWAT from a ( n \u003d 4 biologically independent samples). c Relative expression of Spp1 in the adipocyte fraction ... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Jan 20, 2022, 5:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Nature communications','journalText':'Nature communications 2022 - ','sourceType':'3','benchsci':true,'imageName':'tfs_19070_41467_2021_27683_Fig5_HTML.jpg','benchSciPubmedId':'35058428'},{'sku':'15-0112-82','imageId':'926374','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_19068_cells-10-03181-g003.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_19068_cells-10-03181-g003.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_19068_cells-10-03181-g003.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_19068_cells-10-03181-g003.jpg?time\u003d20240507','sortOrder':'24','description':'Figure 3 Flavivirus infection resulted in peripheral immune cell infiltration and inflammatory activation in the brain. In DENV-, JEV-, and ZIKV-infected hippocampi, hematoxylin \u0026 eosin staining (H\u0026E) showed cell infiltration ( A ). ( B ) Immunofluorescent staining of Iba1 (green) indicated macrophage expression. DAPI (blue) was stained for nuclei. ( C ) The gating strategy in specific regions (R1-3) used to identify resident macrophages or microglia (RM, CD45 low CD11b + ) and infiltrated macrophages (IM, CD45 high CD11b + ). ( D ) The quantitative number of RMs and IMs in DENV-, JEV-, and ZIKV-infected brains ( n \u003d 3). ( E ) Immunoprofile of macrophage polarization toward type 1 (CD80 and CD86) or type 2 (CD163 and CD206) in the RM and IM of infected mice ( n \u003d 3). * p \u003c 0.05, ** p \u003c 0.01, and *** p \u003c 0.001; ns, not significant. ( F ) Gene ontology enrichment analysis showed the changed gene count involving the inflammatory activation pathway. ( G ) Venn diagrams showed the commonality of inflammatory gene expression in three flavivirus infections. Scale bar \u003d 400 mum.','shortDescription':'Figure 3 Flavivirus infection resulted in peripheral immune cell infiltration and inflammatory activation in the brain. In DENV-, JEV-, and ZIKV-infected hippocampi, hematoxylin \u0026 eosin staining (H\u0026E) showed cell infiltration ( A ). ( B ) Immunofluorescent staining of Iba1 (green) indicated macrophage expression. DAPI (blue) was stained for nuclei. ( C ) The gating strategy in specific regions (R1-3) used t... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Nov 15, 2021, 5:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Cells','journalText':'Cells 2021 - ','sourceType':'3','benchsci':true,'imageName':'tfs_19068_cells-10-03181-g003.jpg','benchSciPubmedId':'34831405'},{'sku':'15-0112-82','imageId':'926354','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_19067_fimmu-12-686769-g003.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_19067_fimmu-12-686769-g003.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_19067_fimmu-12-686769-g003.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_19067_fimmu-12-686769-g003.jpg?time\u003d20240507','sortOrder':'25','description':'Figure 3 ADRbeta3+ cells express several macrophage markers, but lack expression of CD11b and F4/80. Macrophage surface markers were quantified on ADRbeta3+ macrophages, bone-marrow-derived macrophages(BMDM), and microglia. Comparisons were made between these cell types to determine commonality. Significant differences (p\u003c0.5) were calculated using an ANOVA with Tukey correction. Symbols represent sample data points, and horizontal lines depict the mean. Standard error of the mean (SEM) is shown by the capped vertical line. *p \u003c 0.05, ***p \u003c 0.001. Flow cytometry was used to quantitate all types of macrophages in both the Figure 3 legend as well as in the test in the Results. Adrb3+ macrophages, BMDM, and microglia were compared for percent positivity to (A) Adrb3; (B) Csf1r; (C) Mrc1; (D) Cd45; (E) Cd68; (F) Cd11b; (G) F4/80; (H) Ccr2; and (I) , Tmem119.','shortDescription':'Figure 3 ADRbeta3+ cells express several macrophage markers, but lack expression of CD11b and F4/80. Macrophage surface markers were quantified on ADRbeta3+ macrophages, bone-marrow-derived macrophages(BMDM), and microglia. Comparisons were made between these cell types to determine commonality. Significant differences (p\u003c0.5) were calculated using an ANOVA with Tukey correction. Symbols represent sample da... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Dec 13, 2021, 5:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Frontiers in immunology','journalText':'Frontiers in immunology 2021 - ','sourceType':'3','benchsci':true,'imageName':'tfs_19067_fimmu-12-686769-g003.jpg','benchSciPubmedId':'34712222'},{'sku':'15-0112-82','imageId':'1019246','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_19067_fimmu-12-686769-g004.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_19067_fimmu-12-686769-g004.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_19067_fimmu-12-686769-g004.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_19067_fimmu-12-686769-g004.jpg?time\u003d20240507','sortOrder':'26','description':'ADRbeta3+ macrophages show sensitivity to clodronate liposomes. (A) Quantitation of ADRbeta3+ cells or (B) Cd11b+ macrophages by flow cytometry in tissues isolated 4 days after induction of HO in mice in the presence of clodronate or saline liposomes. (C) Analysis of bone volume in tissues isolated 2 weeks after induction of HO in mice in the presence of clodronate or saline liposomes using microCT. Significant differences (p\u003c0.5) were calculated using an ANOVA with Tukey correction. Symbols represent sample data points, and horizontal lines depict the mean. Standard error of the mean (SEM) is shown by the capped vertical line. *p \u003c 0.05, **p \u003c 0.01. (D) Individual slices of both saline- and clodronate-treated samples were compared. Also shown for comparison is the mineral density of heterotopic bone.','shortDescription':'ADRbeta3+ macrophages show sensitivity to clodronate liposomes. (A) Quantitation of ADRbeta3+ cells or (B) Cd11b+ macrophages by flow cytometry in tissues isolated 4 days after induction of HO in mice in the presence of clodronate or saline liposomes. (C) Analysis of bone volume in tissues isolated 2 weeks after induction of HO in mice in the presence of clodronate or saline liposomes using microCT. Signifi... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Dec 13, 2021, 5:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Frontiers in immunology','journalText':'Frontiers in immunology 2021 - ','sourceType':'3','benchsci':true,'imageName':'tfs_19067_fimmu-12-686769-g004.jpg','benchSciPubmedId':'34712222'},{'sku':'15-0112-82','imageId':'926273','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_14986_fphar-12-726586-g003.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_14986_fphar-12-726586-g003.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_14986_fphar-12-726586-g003.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_14986_fphar-12-726586-g003.jpg?time\u003d20240507','sortOrder':'27','description':'FIGURE 3 E-cigarette increases macrophage numbers in lungs. (A,C) FACS analysis of cell population of CD45 + F4/80 + macrophages and CD11b + Ly6G + neutrophils in lung tissues of betaENaC mice with or without ENDS exposure ( n \u003d 3 per group). (B,D) Quantification of FCAS analysis of macrophage and neutrophil population as in (A) and (C) , respectively. All data presented at mean +- SEM.','shortDescription':'FIGURE 3 E-cigarette increases macrophage numbers in lungs. (A,C) FACS analysis of cell population of CD45 + F4/80 + macrophages and CD11b + Ly6G + neutrophils in lung tissues of betaENaC mice with or without ENDS exposure ( n \u003d 3 per group). (B,D) Quantification of FCAS analysis of macrophage and neutrophil population as in (A) and (C) , respectively. All data presented at mean +- SEM.','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Apr 2, 2022, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Frontiers in pharmacology','journalText':'Frontiers in pharmacology 2022 - ','sourceType':'3','benchsci':true,'imageName':'tfs_14986_fphar-12-726586-g003.jpg','benchSciPubmedId':'34393802'},{'sku':'15-0112-82','imageId':'926173','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_14981_fimmu-12-701415-g001.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_14981_fimmu-12-701415-g001.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_14981_fimmu-12-701415-g001.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_14981_fimmu-12-701415-g001.jpg?time\u003d20240507','sortOrder':'28','description':'Figure 1 Desiccation stress recruits monocytes into the conjunctiva in a CCR2 dependent manner. The gating strategy used for these experiments is provided in Supplementary Figure 1A . (A) Single cell suspensions prepared from conjunctivae of C57BL/6 (B6) and Ccr2 -/- strains were stained with anti-CD45, CD11b, MHCII, CD64, Ly6c and MerTK. Squares within the representative plots show frequency of CD45 + CD11b + MHCII - CD64 + Ly6C high (classical monocytes) and CD45 + CD11b + MerTK + (tissue resident macrophages) cells (n \u003d 6/group); (B) Experimental design, bone marrow cells from Pepc/BoyJ (2x10^6) were adoptively transfer via intra-orbital injection at 2 day time intervals and the recipient mice either remained in normal environmental conditions (NS) or were exposed to desiccating stress for 5 days (DS5) (n \u003d 6/group); (C) relative fold change in CCL2 mRNA after desiccating stress for 1 day (DS1) (n \u003d 6/group); (D) Adoptively transferred cells were tracked by gating on CD45.1 + , squares within the representative plots showing frequency of classical monocytes (top) and CD45 + CD11b + MHCII + cells (bottom). The bar graphs on the right side indicate the percentages of these cells with each dot representing one animal (n \u003d 6/group); (E) Ccr2 -/- /Ccr2 +/+ bone marrow chimera. Bone marrow ablation in Pepc/BoyJ mice was accomplished with 137 Cs irradiation with 1300 cGy, followed by intraorbitally injection of 2x10^6 bone marrow cells from Ccr2 -/- /CD45.2 (2x10^6) or wild type','shortDescription':'Figure 1 Desiccation stress recruits monocytes into the conjunctiva in a CCR2 dependent manner. The gating strategy used for these experiments is provided in Supplementary Figure 1A . (A) Single cell suspensions prepared from conjunctivae of C57BL/6 (B6) and Ccr2 -/- strains were stained with anti-CD45, CD11b, MHCII, CD64, Ly6c and MerTK. Squares within the representative plots show frequency of CD45 + CD11... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Dec 10, 2021, 5:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Frontiers in immunology','journalText':'Frontiers in immunology 2021 - ','sourceType':'3','benchsci':true,'imageName':'tfs_14981_fimmu-12-701415-g001.jpg','benchSciPubmedId':'34305940'},{'sku':'15-0112-82','imageId':'926193','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_14981_fimmu-12-701415-g002.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_14981_fimmu-12-701415-g002.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_14981_fimmu-12-701415-g002.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_14981_fimmu-12-701415-g002.jpg?time\u003d20240507','sortOrder':'29','description':'Figure 2 Immune cells phenotype in the conjunctiva of B6 mice following desiccation stress. The gating strategy used for these experiments is provided in Supplementary Figure 1A . (A) Single cell suspensions prepared from conjunctivae of C57BL/6 (B6) mice housed in normal humidity (NS) or exposed to desiccating stress for 3 (DS3) or 5 (DS5) days were stained with anti-CD45, CD11b, MHCII, CD64, Ly6c and CD11c. A dump channel (anti-NK1.1/Ly6G/CD3e/CD45R/B220) was included to remove NK cell, granulocyte, T cell and B cells lineages. The four quadrants of the representative plots show percentages of the selected population. (B) Flow cytometry data from each group are visually presented in the bar graphs (n\u003d6, dots are individual samples). The non-stressed (NS) group was statistically compared with the DS3 or DS5 groups using the Student T-test; (C) Representative flow plots of Ly6C and MHCII in the NS, DS3 and DS5 groups (left) with histograms of mean fluorescence intensities (MFI) (right); (D) MFI of CD64 + cells among MHCII - Ly6c high and MHCII + Ly6c low population. *p \u003c 0.01, **p \u003c 0.001, ***p \u003c 0.0001.','shortDescription':'Figure 2 Immune cells phenotype in the conjunctiva of B6 mice following desiccation stress. The gating strategy used for these experiments is provided in Supplementary Figure 1A . (A) Single cell suspensions prepared from conjunctivae of C57BL/6 (B6) mice housed in normal humidity (NS) or exposed to desiccating stress for 3 (DS3) or 5 (DS5) days were stained with anti-CD45, CD11b, MHCII, CD64, Ly6c and CD11... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Dec 10, 2021, 5:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Frontiers in immunology','journalText':'Frontiers in immunology 2021 - ','sourceType':'3','benchsci':true,'imageName':'tfs_14981_fimmu-12-701415-g002.jpg','benchSciPubmedId':'34305940'},{'sku':'15-0112-82','imageId':'926213','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_14981_Image_1.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_14981_Image_1.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_14981_Image_1.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_14981_Image_1.jpg?time\u003d20240507','sortOrder':'30','description':'Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry','shortDescription':'Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Dec 10, 2021, 5:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Frontiers in immunology','journalText':'Frontiers in immunology 2021 - ','sourceType':'3','benchsci':true,'imageName':'tfs_14981_Image_1.jpg','benchSciPubmedId':'34305940'},{'sku':'15-0112-82','imageId':'926253','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_14984_aging-13-203340-g006.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_14984_aging-13-203340-g006.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_14984_aging-13-203340-g006.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_14984_aging-13-203340-g006.jpg?time\u003d20240507','sortOrder':'31','description':'Figure 6 Myeloid DJ-1 deficiency attenuates APAP induced hepatic inflammatory reaction via less ROS production and chemokines induction. Fasted DJ-1 fl/fl and Lysm-DJ-1 -/- mice were intraperitoneal injected with a single dose of 300 mg/kg of APAP. Quantification of Ly6G + CD11b + neutrophils ( A ) and Ly6C + CD11b + macrophages ( B ) by flow cytometry ( n \u003d 4). ( C ) Quantification of CXCL1 and CXCL2 expression in liver tissue 24 h after APAP challenge ( n \u003d 5-8). ( D ) Quantification of cellular ROS levels by oxidized DCFDA and flow cytometry in neutrophils and macrophages isolated from DJ-1 fl/fl and Lysm-DJ-1 -/- mice ( n \u003d 4). Data are shown as the means +- SD, * P \u003c 0.05; ** P \u003c 0.01; *** P \u003c 0.001; **** P \u003c 0.0001.','shortDescription':'Figure 6 Myeloid DJ-1 deficiency attenuates APAP induced hepatic inflammatory reaction via less ROS production and chemokines induction. Fasted DJ-1 fl/fl and Lysm-DJ-1 -/- mice were intraperitoneal injected with a single dose of 300 mg/kg of APAP. Quantification of Ly6G + CD11b + neutrophils ( A ) and Ly6C + CD11b + macrophages ( B ) by flow cytometry ( n \u003d 4). ( C ) Quantification of CXCL1 and CXCL2 expre... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Jul 21, 2021, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Aging','journalText':'Aging 2021 - ','sourceType':'3','benchsci':true,'imageName':'tfs_14984_aging-13-203340-g006.jpg','benchSciPubmedId':'34289451'},{'sku':'15-0112-82','imageId':'926334','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_14993_gr8.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_14993_gr8.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_14993_gr8.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_14993_gr8.jpg?time\u003d20240507','sortOrder':'32','description':'Figure 8 Combination of chemotherapy and immune activation within intratumoral TLSs is necessary for antitumor activity. ( A ) Schema of short-term administration of gemcitabine in combination or not with intratumoral injection of lymphoid chemokines CXCL13 and CCL21 in orthotopic mice. ( B ) TLS density after coinjection of gemcitabine and chemokine (C+G) compared with appropriate controls (PBS [S], chemokine [C], or gemcitabine [G] alone. ( C ) Flow cytometric analysis of CD45 + immune cells in PBS-treated (S) (n \u003d 7) gemcitabine-treated (G) (n \u003d 9) mice, chemokine-treated (C) (n \u003d 6), and C+G-treated (n \u003d 8) mice. Flow cytometric analysis of lymphoid and myeloid immune cells per gram of tumor tissue after chemokine and/or chemotherapy injection. ( D ) B cells (CD19 + ), ( E ) CD3 + T cells, ( F ) CD8 + T cells, ( G ) CD4 + T cells, ( H ) dendritic cells (CD11c + ), ( I ) myeloid cells (CD11b + ), ( J ) MDSC Ly6GC + subset, ( K ) macrophages (F4/80 + , MHC-II + ). ( L ) Tumor volume in C+G-coinjected mice and appropriate controls (chemokines [C], or gemcitabine [G] alone). Each data point represents 1 mouse (S n \u003d 7, C n \u003d 6, G n \u003d 9, C+G n \u003d 9). Kolmogorov-Smirnov test. * P \u003c .05, ** P \u003c .01, *** P \u003c .001.','shortDescription':'Figure 8 Combination of chemotherapy and immune activation within intratumoral TLSs is necessary for antitumor activity. ( A ) Schema of short-term administration of gemcitabine in combination or not with intratumoral injection of lymphoid chemokines CXCL13 and CCL21 in orthotopic mice. ( B ) TLS density after coinjection of gemcitabine and chemokine (C+G) compared with appropriate controls (PBS [S], chemok... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Mar 28, 2022, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Cellular and molecular gastroenterology and hepatology','journalText':'Cellular and molecular gastroenterology and hepatology 2022 - ','sourceType':'3','benchsci':true,'imageName':'tfs_14993_gr8.jpg','benchSciPubmedId':'34252585'},{'sku':'15-0112-82','imageId':'926314','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_14993_gr7.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_14993_gr7.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_14993_gr7.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_14993_gr7.jpg?time\u003d20240507','sortOrder':'33','description':'Figure 7 Differential immune cell infiltration after chemokine injection in orthotopic murine tumors. Flow cytometric analysis, in lymphoid aggregate negative tumors from PBS-treated (n \u003d 6) and TLS + CXCL13/CCL21-treated (n \u003d 6) mice, of ( A ) CD19 + B cells out of CD45 + cells, ( B ) CD3 + T cells out of CD45 + cells, ( C ) CD8 + cytotoxic T cells out of CD3 + T cells, ( D ) CD4 + helper T cells out of CD3 + T cells, ( E ) FOXP3 + regulatory T cells out of CD4+CD3 + T cells, ( F ) CD11b + myeloid cells out of CD45 + cells, and ( G ) tumor weight in LA - tumors from PBS-treated (n \u003d 6) and TLS + CXCL13/CCL21-treated (n \u003d 6) mice. Each data point represents 1 mouse. Two-sample Kolmogorov-Smirnov test: * P \u003c .05 and ** P \u003c .01. ns, not significant.','shortDescription':'Figure 7 Differential immune cell infiltration after chemokine injection in orthotopic murine tumors. Flow cytometric analysis, in lymphoid aggregate negative tumors from PBS-treated (n \u003d 6) and TLS + CXCL13/CCL21-treated (n \u003d 6) mice, of ( A ) CD19 + B cells out of CD45 + cells, ( B ) CD3 + T cells out of CD45 + cells, ( C ) CD8 + cytotoxic T cells out of CD3 + T cells, ( D ) CD4 + helper T cells out of CD... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Mar 28, 2022, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Cellular and molecular gastroenterology and hepatology','journalText':'Cellular and molecular gastroenterology and hepatology 2022 - ','sourceType':'3','benchsci':true,'imageName':'tfs_14993_gr7.jpg','benchSciPubmedId':'34252585'},{'sku':'15-0112-82','imageId':'926293','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_14992_jrd-67-257-g006.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_14992_jrd-67-257-g006.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_14992_jrd-67-257-g006.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_14992_jrd-67-257-g006.jpg?time\u003d20240507','sortOrder':'34','description':'Fig. 6. Effects of maternal aging on immune cell populations in the placenta and spleen. The placenta and spleen were collected from young, middle, and aged pregnant mice. Percentages of immune cells (CD45 + cells), neutrophils (CD45 + /Ly6G + cells or CD45 + /CD11b + cells), macrophages (CD45 + /F4/80 cells) in the placenta and spleen were analyzed by flow cytometry (A-H). Significant differences were detected using nonparametric analysis of variance; * P \u003c 0.05.','shortDescription':'Fig. 6. Effects of maternal aging on immune cell populations in the placenta and spleen. The placenta and spleen were collected from young, middle, and aged pregnant mice. Percentages of immune cells (CD45 + cells), neutrophils (CD45 + /Ly6G + cells or CD45 + /CD11b + cells), macrophages (CD45 + /F4/80 cells) in the placenta and spleen were analyzed by flow cytometry (A-H). Significant differences were dete... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Aug 27, 2021, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'The Journal of reproduction and development','journalText':'The Journal of reproduction and development 2021 - ','sourceType':'3','benchsci':true,'imageName':'tfs_14992_jrd-67-257-g006.jpg','benchSciPubmedId':'34176822'},{'sku':'15-0112-82','imageId':'926152','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_14980_40820_2020_540_Fig2_HTML.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_14980_40820_2020_540_Fig2_HTML.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_14980_40820_2020_540_Fig2_HTML.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_14980_40820_2020_540_Fig2_HTML.jpg?time\u003d20240507','sortOrder':'35','description':'Fig. 2 a Schematic diagram of biomaterial-mediated macrophage polarization and MSC osteogenesis. b FACS of all macrophages (F4/80 + , CD11b +), M2 macrophages (F4/80 + , CD11b + , CD206 high , MHC II low ) and M1 macrophages (F4/80 + , CD11b + , CD206 low , MHC II high ) recruitment at 2 weeks after biomaterials implantation in vivo. c Semiquantification of gating strategy cells in (B). n \u003d 6, **** P \u003c 0.0001, ns: not significant. d IHC staining of F4/80--macrophage marker, Arg1--M2 macrophage marker and iNOS--M1 macrophage marker at 4 weeks after biomaterials implantation in vivo. Red arrow, positive cell. Scale bar \u003d 100 mum. M, material. e Semiquantification of positively stained cells in ( d ). n \u003d 5, *** P \u003c 0.001, **** P \u003c 0.0001, ns: not significant. f Immunofluorescent (IF) staining of Arg1 (red), iNOS (green) and nuclei (blue) after macrophages seeded on the BCP or beta -TCP for 24 h. Scale bar \u003d 5 mum. g Semiquantification of positively stained cells in ( f ). n \u003d 5, **** P \u003c 0.0001. h Relative mRNA expressions of macrophage polarization-related genes. M2 macrophage polarization-related anti-inflammatory genes (Arg1, IL-10) and the M1 macrophage-related pro-inflammatory gene (TNF-alpha, iNOS). n \u003d 3, ** P \u003c 0.01, *** P \u003c 0.001, **** P \u003c 0.0001. i, j ARS staining of MSCs on day 21 and semiquantification of mineralized nodules. n \u003d 3, ** P \u003c 0.01, *** P \u003c 0.001, **** P \u003c 0.0001','shortDescription':'Fig. 2 a Schematic diagram of biomaterial-mediated macrophage polarization and MSC osteogenesis. b FACS of all macrophages (F4/80 + , CD11b +), M2 macrophages (F4/80 + , CD11b + , CD206 high , MHC II low ) and M1 macrophages (F4/80 + , CD11b + , CD206 low , MHC II high ) recruitment at 2 weeks after biomaterials implantation in vivo. c Semiquantification of gating strategy cells in (B). n \u003d 6, **** P \u003c 0.00... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Nov 21, 2020, 5:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Nano-micro letters','journalText':'Nano-micro letters 2020 - ','sourceType':'3','benchsci':true,'imageName':'tfs_14980_40820_2020_540_Fig2_HTML.jpg','benchSciPubmedId':'34138183'},{'sku':'15-0112-82','imageId':'926233','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_14983_ADVS-8-2100787-g006.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_14983_ADVS-8-2100787-g006.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_14983_ADVS-8-2100787-g006.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_14983_ADVS-8-2100787-g006.jpg?time\u003d20240507','sortOrder':'36','description':'Figure 5 Biodistribution and targeting specificity of PLM-miRs in vivo. A) Circulation profiles of miRs, MSN-miRs, LM-miRs, and PLM-miRs in healthy mice after intravenous injection ( n \u003d 6). B) RFI of heart tissue homogenate after treated with DiD (on liposome) labeled LM-miRs or PLM-miRs at 24 or 48 h post injury ( n \u003d 6). C) IVIS images of three timepoints (1, 3, 24 h) of LM-miRs or PLM-miRs accumulated in the hearts after i.v. injected in MI/R mice and D) were further quantified the data of the first time point ( n \u003d 6). E) Flow cytometry analysis of the binding ability of PLM-miRs to Ly6C+ monocytes in the blood circulation after intravenous injection at 72 h post-MI and G) was further quantified ( n \u003d 6). F) Flow cytometry and statistical analysis of H) CD11b+, I) CD11b+DiD+, and J) CD11b+DiD- cells isolated from MI/R induced murine hearts after exposure to either LM-miRs or PLM-miRs injected at 24 or 72 h post-MI ( n \u003d 6). K) CLSM images of heart sections showing the accumulation of LM-miRs and PLM-miRs after immuno-stained with cardiac troponin T (cTnT). Red, DiD (on liposome) labeled nanoparticles; Green, TnT. Scalar bar, 50 um. L) CLSM images of heart sections showing the colocalization between monocytes/macrophages and LM-miRs or PLM-miRs after immuno-stained with CD11b. Red, DiD (on liposome) labeled nanoparticles; Green, CD11b. Scalar bar, 20 um. Results are presented as mean +- SD. NS P \u003e 0.05, * P \u003c 0.05, ** P \u003c 0.01, *** P \u003c 0.001.','shortDescription':'Figure 5 Biodistribution and targeting specificity of PLM-miRs in vivo. A) Circulation profiles of miRs, MSN-miRs, LM-miRs, and PLM-miRs in healthy mice after intravenous injection ( n \u003d 6). B) RFI of heart tissue homogenate after treated with DiD (on liposome) labeled LM-miRs or PLM-miRs at 24 or 48 h post injury ( n \u003d 6). C) IVIS images of three timepoints (1, 3, 24 h) of LM-miRs or PLM-miRs accumulated i... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Aug 1, 2021, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Advanced science (Weinheim, Baden-Wurttemberg, Germany)','journalText':'Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2021 - ','sourceType':'3','benchsci':true,'imageName':'tfs_14983_ADVS-8-2100787-g006.jpg','benchSciPubmedId':'34137511'},{'sku':'15-0112-82','imageId':'926132','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_14979_41467_2021_23832_Fig1_HTML.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_14979_41467_2021_23832_Fig1_HTML.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_14979_41467_2021_23832_Fig1_HTML.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_14979_41467_2021_23832_Fig1_HTML.jpg?time\u003d20240507','sortOrder':'37','description':'Fig. 1 Genetic ablation of IL-6 reverses GBM immunosuppression. GBM was induced by RCAS-mediated genetic engineering in Ntv-a ; Ink4a-Arf -/- ; Pten fl/fl ; LSL-Luc donor mice, followed by orthotopic tumor implantation into Cdh5-Cre ERT2 ; Il6 fl/fl recipient mice that were pretreated with (IL-6-DeltaEC) or without (Control) tamoxifen. Two weeks after tumor implantation, tumors were excised. a Schematic approach. b , c Tumor-derived single-cell suspensions were analyzed by CyTOF. b Representative CyTOF sorting. c Quantitative results (mean +- SEM, n \u003d 4 mice). Statistical analysis by two-tailed Student\u0027s t -test. d - f Tumor-derived single-cell suspensions were analyzed by flow cytometry. d Analysis for CD3 + T cells. Left, representative cell sortings. Right, quantified results ( n \u003d 6 mice, mean +- SEM). Statistical analysis by two-tailed Student\u0027s t -test. e , f Analysis for e CD4 + /CD8 + T cells or f myeloid cells ( n \u003d 6 mice, mean +- SEM). Statistical analysis by two-tailed Student\u0027s t -test. g , h Tissue lysates from normal brains and tumors were subjected to ELISA analysis for g IL-10 and h TGF-beta expression (mean +- SEM, n \u003d 4 mice for IL-6-DeltaEC GBM group and n \u003d 3 mice for other groups). Statistical analysis by two-way ANOVA with Sidak\u0027s test. Source data are provided as a Source data file.','shortDescription':'Fig. 1 Genetic ablation of IL-6 reverses GBM immunosuppression. GBM was induced by RCAS-mediated genetic engineering in Ntv-a ; Ink4a-Arf -/- ; Pten fl/fl ; LSL-Luc donor mice, followed by orthotopic tumor implantation into Cdh5-Cre ERT2 ; Il6 fl/fl recipient mice that were pretreated with (IL-6-DeltaEC) or without (Control) tamoxifen. Two weeks after tumor implantation, tumors were excised. a Schematic app... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Jun 8, 2021, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Nature communications','journalText':'Nature communications 2021 - ','sourceType':'3','benchsci':true,'imageName':'tfs_14979_41467_2021_23832_Fig1_HTML.jpg','benchSciPubmedId':'34103524'},{'sku':'15-0112-82','imageId':'926112','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_14978_10020_2021_325_Fig4_HTML.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_14978_10020_2021_325_Fig4_HTML.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_14978_10020_2021_325_Fig4_HTML.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_14978_10020_2021_325_Fig4_HTML.jpg?time\u003d20240507','sortOrder':'38','description':'Fig.4 Infiltrating monocytes and neutrophils were deceased in CD36 -/- mice. LMNCs were purified from APAP treated mice and stained with CD11b, Ly6C and Ly6G antibodies. Infiltrating monocytes (CD11b + Ly6C + ) and neutrophils (CD11b + Ly6G + ) were analyzed by FACS. *P \u003c 0.05. N \u003d 6 mice per group','shortDescription':'Fig.4 Infiltrating monocytes and neutrophils were deceased in CD36 -/- mice. LMNCs were purified from APAP treated mice and stained with CD11b, Ly6C and Ly6G antibodies. Infiltrating monocytes (CD11b + Ly6C + ) and neutrophils (CD11b + Ly6G + ) were analyzed by FACS. *P \u003c 0.05. N \u003d 6 mice per group','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Jun 6, 2021, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Molecular medicine (Cambridge, Mass.)','journalText':'Molecular medicine (Cambridge, Mass.) 2021 - ','sourceType':'3','benchsci':true,'imageName':'tfs_14978_10020_2021_325_Fig4_HTML.jpg','benchSciPubmedId':'34092215'},{'sku':'15-0112-82','imageId':'926092','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_14990_pone.0252642.g005.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_14990_pone.0252642.g005.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_14990_pone.0252642.g005.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_14990_pone.0252642.g005.jpg?time\u003d20240507','sortOrder':'39','description':'10.1371/journal.pone.0252642.g005 Fig 5 Innate immune responses at PN25 compared with PN12 in Wt offspring from dams exposed to LPS at a dose of 90 ug/kg (LPS90) late in gestation. LPS administered i.p. to pregnant Wt dams at E15.5. Expression of splenic innate immune cells and intracellular HO-1 in Wt offspring were determined at PN25 by flow cytometry (Wt LPS90 PN12, n \u003d 4; Wt LPS90 PN25, n \u003d 4). CD45 + common leukocyte antigen. CD11b + Ly6G + neutrophils. CD11b + CD11c + DCs. CD11b + Ly6C + (mononuclear cells). Intracellular HO-1 expression in neutrophils, DCs, and monocytes. Cell populations are shown as percentages of CD45 + cells and intracellular HO-1 expression as median fluorescent intensities (MFIs). Values are expressed as mean +- SD, p \u003c 0.05, Student\u0027s t-test with Welch correction.','shortDescription':'10.1371/journal.pone.0252642.g005 Fig 5 Innate immune responses at PN25 compared with PN12 in Wt offspring from dams exposed to LPS at a dose of 90 ug/kg (LPS90) late in gestation. LPS administered i.p. to pregnant Wt dams at E15.5. Expression of splenic innate immune cells and intracellular HO-1 in Wt offspring were determined at PN25 by flow cytometry (Wt LPS90 PN12, n \u003d 4; Wt LPS90 PN25, n \u003d 4). CD45 + c... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Nov 17, 2021, 5:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'PloS one','journalText':'PloS one 2021 - ','sourceType':'3','benchsci':true,'imageName':'tfs_14990_pone.0252642.g005.jpg','benchSciPubmedId':'34086785'},{'sku':'15-0112-82','imageId':'926072','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_14977_41467_2021_23197_Fig5_HTML.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_14977_41467_2021_23197_Fig5_HTML.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_14977_41467_2021_23197_Fig5_HTML.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_14977_41467_2021_23197_Fig5_HTML.jpg?time\u003d20240507','sortOrder':'40','description':'Fig. 5 Gata6 deletion in cavity macrophages did not affect injury repair in the liver. a Schematic figure showing the experimental design. b Flow cytometric and quantification analysis of the percentage CD11b + F4/80 + macrophages expressing tdTomato from the pleural and peritoneal cavity. Data are the mean +- SD; n \u003d 5 mice per group; **** P \u003c 0.0001. c Schemati c figure showing the experimental design. d Immunostaining for tdTomato and F4/80 on dissociated cells from peritoneal cavity at 9 weeks and 13 weeks after TAM. Data are the mean +- SD; n \u003d 5 mice per group. **** P \u003c 0.0001. Each image is representative of five individual biological samples. e , f Flow cytometric analysis and quantification of the percentage of CD11b + F4/80 + macrophages expressing tdTomato. Data are the mean +- SD; n \u003d 5 mice per group; **** P \u003c 0.0001. g Schematic figure showing the experimental design. HI heat injury. h Whole-mount bright-field and fluorescence images of livers collected at 7 days after heart injury. Boxed regions are magnified; circles, heat injury site. Each image is representative of eight individual biological samples. i Quantification of injury size at 4 h and 7 days post HI. Data are the mean +- SD; n \u003d 8 mice per group; ns nonsignificant. j Schematic figure showing the experimental design. k Whole-mount bright-field and fluorescence images of livers collected at 5 days after injury. Each image is representative of five individual biological samples. l Quantification of bod','shortDescription':'Fig. 5 Gata6 deletion in cavity macrophages did not affect injury repair in the liver. a Schematic figure showing the experimental design. b Flow cytometric and quantification analysis of the percentage CD11b + F4/80 + macrophages expressing tdTomato from the pleural and peritoneal cavity. Data are the mean +- SD; n \u003d 5 mice per group; **** P \u003c 0.0001. c Schemati c figure showing the experimental design. d ... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'May 17, 2021, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Nature communications','journalText':'Nature communications 2021 - ','sourceType':'3','benchsci':true,'imageName':'tfs_14977_41467_2021_23197_Fig5_HTML.jpg','benchSciPubmedId':'34001904'},{'sku':'15-0112-82','imageId':'926052','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_14977_41467_2021_23197_Fig4_HTML.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_14977_41467_2021_23197_Fig4_HTML.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_14977_41467_2021_23197_Fig4_HTML.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_14977_41467_2021_23197_Fig4_HTML.jpg?time\u003d20240507','sortOrder':'41','description':'Fig. 4 Genetic ablation of cavity macrophages did not affect liver repair after injury. a Schematic figure showing the experimental design. DT diphtheria toxin. b Flow cytometric and quantification analysis of the percentage of CD11b + F4/80 + macrophages expressing tdTomato from peritoneal cavity after PBS treatment (no DT). Data are the mean +- SD; n \u003d 5 mice per group; ns nonsignificant. c Immunostaining for tdTomato and F4/80 on dissociated cells from the peritoneal or pleural cavity after DT treatment of the G6Mo-CreER;R26-tdTomato/iDTR mice. Quantification of the percentage of F4/80 + macrophages expressing tdTomato. Data are the mean +- SD; n \u003d 5 mice per group; **** P \u003c 0.0001. Each image is representative of five individual biological samples. d Flow cytometric and quantification analysis of the percentage of CD11b + F4/80 + macrophages expressing tdTomato in the pleural cavity, and peritoneal cavity, respectively. Data are the mean +- SD; n \u003d 5 mice per group; **** P \u003c 0.0001. e Schematic figure showing the experimental design. HI heat injury. f Whole-mount bright-field and fluorescence images of livers at 7 days after HI. Boxed regions are magnified; circles, heat injury site. Each image is representative of eight individual biological samples. g Quantification of injury size from 4 h to 7 days after heart injury. Data are the mean +- SD; n \u003d 8 mice per group; ns nonsignificant. h Schematic figure showing the experimental design. i Whole-mount bright-field and fluo','shortDescription':'Fig. 4 Genetic ablation of cavity macrophages did not affect liver repair after injury. a Schematic figure showing the experimental design. DT diphtheria toxin. b Flow cytometric and quantification analysis of the percentage of CD11b + F4/80 + macrophages expressing tdTomato from peritoneal cavity after PBS treatment (no DT). Data are the mean +- SD; n \u003d 5 mice per group; ns nonsignificant. c Immunostaining... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'May 17, 2021, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Nature communications','journalText':'Nature communications 2021 - ','sourceType':'3','benchsci':true,'imageName':'tfs_14977_41467_2021_23197_Fig4_HTML.jpg','benchSciPubmedId':'34001904'},{'sku':'15-0112-82','imageId':'926032','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_14977_41467_2021_23197_Fig3_HTML.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_14977_41467_2021_23197_Fig3_HTML.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_14977_41467_2021_23197_Fig3_HTML.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_14977_41467_2021_23197_Fig3_HTML.jpg?time\u003d20240507','sortOrder':'42','description':'Fig. 3 Pleural macrophages do not invade deep into the lung parenchyma after bleomycin treatment or CI. a Schematic figure showing experimental strategies. CI cryoinjury. b Whole-mount bright-field and fluorescent images of lungs after different injuries. Dotted line, CI region. Scale bars, 1 mm. c Sirius red staining of lung tissue sections after bleomycin or cryoinjury in lungs. Boxed regions are magnified. Scale bars, 100 um. d Immunostaining for tdTomato, GATA6, and F4/80 on injured regions of lungs. m.l., mesothelial layer. Boxed regions are magnified. Scale bars, 100 um. e , f FACS and quantification analysis of the percentage of macrophages expressing tdTomato from injury regions of the lung. Data are the mean +- SD; n \u003d 5 mice per group. Each image is representative of five individual biological samples ( b - d ). Source data are provided as a Source Data file.','shortDescription':'Fig. 3 Pleural macrophages do not invade deep into the lung parenchyma after bleomycin treatment or CI. a Schematic figure showing experimental strategies. CI cryoinjury. b Whole-mount bright-field and fluorescent images of lungs after different injuries. Dotted line, CI region. Scale bars, 1 mm. c Sirius red staining of lung tissue sections after bleomycin or cryoinjury in lungs. Boxed regions are magnifie... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'May 17, 2021, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Nature communications','journalText':'Nature communications 2021 - ','sourceType':'3','benchsci':true,'imageName':'tfs_14977_41467_2021_23197_Fig3_HTML.jpg','benchSciPubmedId':'34001904'},{'sku':'15-0112-82','imageId':'926012','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_14976_PHY2-9-e14859-g005.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_14976_PHY2-9-e14859-g005.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_14976_PHY2-9-e14859-g005.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_14976_PHY2-9-e14859-g005.jpg?time\u003d20240507','sortOrder':'43','description':'FIGURE 1 Long-term exercise restores the foreign-body phagocytic capacity of Kupffer cells (KCs) in p62 -KO mice. (a) Blood lactate concentration pre- and post-exercise. The body mass of wild-type mice fed a standard diet (WT, n \u003d 3), resting p62 -KO mice fed a standard diet ( p62 -KO-Rest, n \u003d 8), and p62 -KO fed a standard diet that exercised for 4 weeks ( p62 -KO-Ex, n \u003d 8). (b) Latex bead-phagocytic capacity of F4/80 positive cells (KCs) and their mean fluorescence intensity (MFI) in the livers of mice in each group. The MFI of the latex beads was determined using flow cytometry ( n \u003d 3/group). (c and d) Expression of the surface markers CD68 and toll-like receptor (TLR) 4 (C), and CD11b (M1) and CD206 (M2) (d) in KCs from the livers of mice in each group ( n \u003d 3-4/group). (e) Lipopolysaccharide (LPS) concentrations in the peripheral and portal circulations and the differences between these ( n \u003d 5-6/group). (f) Dehydroepiandrosterone (DHEA) concentration in the peripheral blood ( n \u003d 6-8/group). Values are mean +- SE. * p \u003c 0.05, compared with the WT group. + p \u003c 0.05, compared with the p62 -KO-Rest group','shortDescription':'FIGURE 1 Long-term exercise restores the foreign-body phagocytic capacity of Kupffer cells (KCs) in p62 -KO mice. (a) Blood lactate concentration pre- and post-exercise. The body mass of wild-type mice fed a standard diet (WT, n \u003d 3), resting p62 -KO mice fed a standard diet ( p62 -KO-Rest, n \u003d 8), and p62 -KO fed a standard diet that exercised for 4 weeks ( p62 -KO-Ex, n \u003d 8). (b) Latex bead-phagocytic cap... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'May 1, 2021, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Physiological reports','journalText':'Physiological reports 2021 - ','sourceType':'3','benchsci':true,'imageName':'tfs_14976_PHY2-9-e14859-g005.jpg','benchSciPubmedId':'33991461'},{'sku':'15-0112-82','imageId':'925220','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_14952_urn-x-wiley-2051817X-media-phy214859-phy214859-fig-0001.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_14952_urn-x-wiley-2051817X-media-phy214859-phy214859-fig-0001.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_14952_urn-x-wiley-2051817X-media-phy214859-phy214859-fig-0001.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_14952_urn-x-wiley-2051817X-media-phy214859-phy214859-fig-0001.jpg?time\u003d20240507','sortOrder':'44','description':'1 FIGURE Long-term exercise restores the foreign-body phagocytic capacity of Kupffer cells (KCs) in p62 -KO mice. (a) Blood lactate concentration pre- and post-exercise. The body mass of wild-type mice fed a standard diet (WT, n \u003d 3), resting p62 -KO mice fed a standard diet ( p62 -KO-Rest, n \u003d 8), and p62 -KO fed a standard diet that exercised for 4 weeks ( p62 -KO-Ex, n \u003d 8). (b) Latex bead-phagocytic capacity of F4/80 positive cells (KCs) and their mean fluorescence intensity (MFI) in the livers of mice in each group. The MFI of the latex beads was determined using flow cytometry ( n \u003d 3/group). (c and d) Expression of the surface markers CD68 and toll-like receptor (TLR) 4 (C), and CD11b (M1) and CD206 (M2) (d) in KCs from the livers of mice in each group ( n \u003d 3-4/group). (e) Lipopolysaccharide (LPS) concentrations in the peripheral and portal circulations and the differences between these ( n \u003d 5-6/group). (f) Dehydroepiandrosterone (DHEA) concentration in the peripheral blood ( n \u003d 6-8/group). Values are mean +- SE. * p \u003c 0.05, compared with the WT group. + p \u003c 0.05, compared with the p62 -KO-Rest group','shortDescription':'1 FIGURE Long-term exercise restores the foreign-body phagocytic capacity of Kupffer cells (KCs) in p62 -KO mice. (a) Blood lactate concentration pre- and post-exercise. The body mass of wild-type mice fed a standard diet (WT, n \u003d 3), resting p62 -KO mice fed a standard diet ( p62 -KO-Rest, n \u003d 8), and p62 -KO fed a standard diet that exercised for 4 weeks ( p62 -KO-Ex, n \u003d 8). (b) Latex bead-phagocytic cap... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'May 1, 2021, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Physiological reports','journalText':'Physiological reports 2021 - ','sourceType':'3','benchsci':true,'imageName':'tfs_14952_urn-x-wiley-2051817X-media-phy214859-phy214859-fig-0001.jpg','benchSciPubmedId':'33991461'},{'sku':'15-0112-82','imageId':'841493','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_12627_jciinsight-6-143379-g148.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_12627_jciinsight-6-143379-g148.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_12627_jciinsight-6-143379-g148.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_12627_jciinsight-6-143379-g148.jpg?time\u003d20240507','sortOrder':'45','description':'Figure 3 Brd4 -CKO mice had reduced expression of Gdf3 in ATMs. ( A ) PCA of RNA-Seq data derived from CD11b + ATMs of WT and Brd4 -CKO mice fed a HFD for 20 weeks. ( B ) Volcano plot of mRNA-Seq analysis in ATMs as indicated in A . Brown dots represent genes increased in ATMs of Brd4 -CKO mice vs. WT mice (fold change \u003e\u003d 2, adjusted P value \u003c\u003d 0.001, calculated by raw count value). Blue dots represent genes decreased in ATMs of Brd4 -CKO mice vs. WT mice (fold change \u003e\u003d 2, adjusted P value \u003c\u003d 0.001, calculated by raw count value). Gray dots represent genes without significantly altered expression. Clusters of significantly altered genes (fold change \u003e\u003d 2, adjusted P value \u003c\u003d 0.001, calculated by raw count value) were identified using gene ontology terms ( C ) and KEGG pathways ( D ). ( E ) Heat map of the relative expression levels (scaled Z -score) of cytokine-cytokine receptor interaction-related genes clustered in ( D ). ( F ) mRNA levels of Gdf3 in CD11b + ATMs isolated from WT or Brd4 -CKO mice fed a HFD for 20 weeks. ( G ) Left panel: Gdf3 or F4/80 IHC staining of eWAT of WT or Brd4-CKO mice fed a HFD for 20 weeks. Right panel: statistical analysis of Gdf3-positive or F4/80-positive area percentage, the ratio of Gdf3-positive cells in F4/80-positive cells in eWAT of WT and Brd4 -CKO mice fed a HFD. Data are mean and SD and are determined by an unpaired 2-tailed Student\u0027\u0027s t test. n \u003d 3 mice. ** P \u003c 0.01. Brd4 -CKO, myeloid lineage-specific Brd4 knockout; HFD, high-fat','shortDescription':'Figure 3 Brd4 -CKO mice had reduced expression of Gdf3 in ATMs. ( A ) PCA of RNA-Seq data derived from CD11b + ATMs of WT and Brd4 -CKO mice fed a HFD for 20 weeks. ( B ) Volcano plot of mRNA-Seq analysis in ATMs as indicated in A . Brown dots represent genes increased in ATMs of Brd4 -CKO mice vs. WT mice (fold change \u003e\u003d 2, adjusted P value \u003c\u003d 0.001, calculated by raw count value). Blue dots represent gene... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Apr 8, 2021, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'JCI insight','journalText':'JCI insight 2021 - ','sourceType':'3','benchsci':true,'imageName':'tfs_12627_jciinsight-6-143379-g148.jpg','benchSciPubmedId':'33830083'},{'sku':'15-0112-82','imageId':'1139527','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_29096_nihms-1689237-f0007.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_29096_nihms-1689237-f0007.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_29096_nihms-1689237-f0007.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_29096_nihms-1689237-f0007.jpg?time\u003d20240507','sortOrder':'46','description':'Figure 6. Decreasing monocyte-derived macrophages enhances CD8 T cell and neutrophil infiltration (A) Ptch1 +/- Tp53 -/- (Ccr2WT) and Ccr2 -/- mice were bred to produce Ptch1 +/- Tp53 -/- Ccr2 -/- (Ccr2KO) mice. (B) Flow cytometry of cerebellar myeloid cells showing reduced Cd11b + Cd45 hi Ly6G - Ly6c hi cells in irradiated Ccr2KO mice. Student\u0027s t test. N \u003d 8 Ccr2WT mice, 6 Ccr2KO mice. Results are expressed as mean +- SEM. *p \u003c\u003d 0.05. (C) UMAP plots of scRNA-seq of cerebellar leukocytes from irradiated Ccr2WT and Ccr2KO showing reduced monocyte-derived macrophages and enhancedneutrophils in the latter. (D) RNAscope in situ with Siglech (black) and Clec12 (red) probes showing reduced accumulation of Clec12a -positive cells in irradiated Ccr2KO in comparison to Ccr2WT of Figure 5C . Scale bar: 50 muM. (E and F) Immunohistochemical staining with Ly6G (E) and CD8 (F) antibody showing an increase in neutrophil and CD8+ T cells in irradiated tumors from Ccr2KO (right plots) compared with Ccr2WT (left plots). Student\u0027s t test. n \u003d 3 animals per treatment group. Results are expressed as mean +- SEM. **p \u003c\u003d 0.01, ***p \u003c\u003d 0.001. Field: 3,190 x 1,974 mum. Scale bar: 200 muM. See also Figure S6 .','shortDescription':'Figure 6. Decreasing monocyte-derived macrophages enhances CD8 T cell and neutrophil infiltration (A) Ptch1 +/- Tp53 -/- (Ccr2WT) and Ccr2 -/- mice were bred to produce Ptch1 +/- Tp53 -/- Ccr2 -/- (Ccr2KO) mice. (B) Flow cytometry of cerebellar myeloid cells showing reduced Cd11b + Cd45 hi Ly6G - Ly6c hi cells in irradiated Ccr2KO mice. Student\u0027s t test. N \u003d 8 Ccr2WT mice, 6 Ccr2KO mice. Results are express... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Mar 30, 2021, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Cell reports','journalText':'Cell reports 2021 - ','sourceType':'3','benchsci':true,'imageName':'tfs_29096_nihms-1689237-f0007.jpg','benchSciPubmedId':'33789113'},{'sku':'15-0112-82','imageId':'925972','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_14989_gr3.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_14989_gr3.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_14989_gr3.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_14989_gr3.jpg?time\u003d20240507','sortOrder':'47','description':'Figure 3 Isolation of TDE-treated DC ex vivo (A) Uptake of PKH67 labeled exosomes by BMDC. (B) Injection of PKH67 labeled exosomes into the mice footpad. (C) Location of popliteal lymph nodes and inguinal lymph nodes of mice. (D) Flow cytometry and gating strategy of PKH67-uptaken DCs.','shortDescription':'Figure 3 Isolation of TDE-treated DC ex vivo (A) Uptake of PKH67 labeled exosomes by BMDC. (B) Injection of PKH67 labeled exosomes into the mice footpad. (C) Location of popliteal lymph nodes and inguinal lymph nodes of mice. (D) Flow cytometry and gating strategy of PKH67-uptaken DCs.','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Mar 19, 2021, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'STAR protocols','journalText':'STAR protocols 2021 - ','sourceType':'3','benchsci':true,'imageName':'tfs_14989_gr3.jpg','benchSciPubmedId':'33786458'},{'sku':'15-0112-82','imageId':'925952','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_14988_41467_2021_22053_Fig1_HTML.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_14988_41467_2021_22053_Fig1_HTML.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_14988_41467_2021_22053_Fig1_HTML.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_14988_41467_2021_22053_Fig1_HTML.jpg?time\u003d20240507','sortOrder':'48','description':'Fig. 1 ASXL1-MT causes dysfunction of HSPCs associated with increased apoptosis and altered cell cycle status. a Enumeration of white blood cells (WBC), hemoglobin (Hb), and platelets (Plt) in peripheral blood of young Vav-Cre ASXL1-MT KI mice ( n \u003d 13 (Control), 11 (ASXL1-MT)). b Frequency of myeloid cells (CD11b + ), B cells (B220 + ), and T cells (CD3 + ) in peripheral white blood cells of young Vav-Cre ASXL1-MT KI mice ( n \u003d 13 (Control), 11 (ASXL1-MT)). c Absolute numbers of bone marrow cells per leg in young Vav-Cre ASXL1-MT KI mice ( n \u003d 5). d Frequency of LSK cells, multipotent progenitors (MPPs), short-term HSCs (ST-HSCs) and long-term HSCs (LT-HSCs) in bone marrow cells of young Vav-Cre ASXL1-MT KI mice ( n \u003d 5). e The experimental design for competitive transplantation assays. 3000 MPPs or 200 LT-HSCs isolated from young control or young Vav-Cre ASXL1-MT KI mice were transplanted into lethally irradiated recipient mice with 4 x 10 5 whole bone marrow cells. f Levels of donor chimerism in peripheral blood were analyzed at the indicated weeks after transplantation ( n \u003d 3 (Control), 4 (ASXL1-MT)). Data are mean +- s.e.m. g Apoptosis analysis of HSPCs of young Vav-Cre ASXL1-MT KI mice ( n \u003d 7). h Cell cycle analysis with Ki-67/DAPI staining of MPPs (left panel) and LT-HSCs (right panel) of young Vav-Cre ASXL1-MT KI mice ( n \u003d 5). Data are mean +- s.d. unless otherwise noted. * P \u003c\u003d 0.05, ** P \u003c\u003d 0.01, *** P \u003c\u003d 0.001; two-tailed Student\u0027s t -test.','shortDescription':'Fig. 1 ASXL1-MT causes dysfunction of HSPCs associated with increased apoptosis and altered cell cycle status. a Enumeration of white blood cells (WBC), hemoglobin (Hb), and platelets (Plt) in peripheral blood of young Vav-Cre ASXL1-MT KI mice ( n \u003d 13 (Control), 11 (ASXL1-MT)). b Frequency of myeloid cells (CD11b + ), B cells (B220 + ), and T cells (CD3 + ) in peripheral white blood cells of young Vav-Cre ... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Mar 23, 2021, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Nature communications','journalText':'Nature communications 2021 - ','sourceType':'3','benchsci':true,'imageName':'tfs_14988_41467_2021_22053_Fig1_HTML.jpg','benchSciPubmedId':'33758188'},{'sku':'15-0112-82','imageId':'925992','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_14850_gr1.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_14850_gr1.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_14850_gr1.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_14850_gr1.jpg?time\u003d20240507','sortOrder':'49','description':'Figure 1 ADU-S100 STING agonist reduces tumor burden and activates the pancreatic cancer immune microenvironment. ( A ) Schematic of experimental treatment plan. C57BL/6 mice were implanted into a single-flank with KPC1242 cells and treated with 2 or 3 intratumoral injections of 450 mug DMXAA ( teal ), 1 mug, 10 mug, 25 mug, or 100 mug ADU-S100 (S100, purple ), or vehicle control ( black ). ( B ) Tumors were harvested after 3 injections and measured ex vivo. ( C ) Tumor volume at study end from mice treated twice with dose titration of S100. ( D ) Kaplan-Meier survival curve with log-rank test analysis ( top panel ) and individual animal PDA tumor area ( bottom panel ) over time. Gray arrows indicate treatment on days 11, 15, and 25. n \u003d 4 (control), n \u003d 6 (S100). ( E and F ) Representative gating strategies for flow cytometric analysis of lymphocyte populations ( E ) and myeloid populations ( F ). Shaded regions indicate selected cell populations in gating scheme. ( G ) Tumors from ( B ) were analyzed by flow cytometry. Error bars represent mean +- standard error of the mean (SEM). n \u003d 3-6. FC, fold-change; MFI, median fluorescence intensity; ns, not significant. * P \u003c .05, ** P \u003c .01, *** P \u003c .001, **** P \u003c .0001.','shortDescription':'Figure 1 ADU-S100 STING agonist reduces tumor burden and activates the pancreatic cancer immune microenvironment. ( A ) Schematic of experimental treatment plan. C57BL/6 mice were implanted into a single-flank with KPC1242 cells and treated with 2 or 3 intratumoral injections of 450 mug DMXAA ( teal ), 1 mug, 10 mug, 25 mug, or 100 mug ADU-S100 (S100, purple ), or vehicle control ( black ). ( B ) Tumors wer... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Jan 24, 2022, 5:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Cellular and molecular gastroenterology and hepatology','journalText':'Cellular and molecular gastroenterology and hepatology 2022 - ','sourceType':'3','benchsci':true,'imageName':'tfs_14850_gr1.jpg','benchSciPubmedId':'33548597'},{'sku':'15-0112-82','imageId':'853803','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_9863_cells-10-00298-g001.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_9863_cells-10-00298-g001.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_9863_cells-10-00298-g001.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_9863_cells-10-00298-g001.jpg?time\u003d20240507','sortOrder':'50','description':'Figure 1 Characterisation of synovial fibroblasts from the temporomandibular joint of BL/6 mice. Spindle-shaped synovial fibroblasts growing out of the synovial tissue on collagen-I-coated flasks 2 weeks after extraction ( A ). The PCR expression analysis of fibroblast-specific-genes ( B ). Proportion of cells expressing cell-surface fibroblast-specific antigens (CD90.2) and leucocyte-specific antigens (CD45.2, CD11b) in the FACS analysis ( C ).','shortDescription':'Figure 1 Characterisation of synovial fibroblasts from the temporomandibular joint of BL/6 mice. Spindle-shaped synovial fibroblasts growing out of the synovial tissue on collagen-I-coated flasks 2 weeks after extraction ( A ). The PCR expression analysis of fibroblast-specific-genes ( B ). Proportion of cells expressing cell-surface fibroblast-specific antigens (CD90.2) and leucocyte-specific antigens (CD4... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Feb 1, 2021, 5:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Cells','journalText':'Cells 2021 - ','sourceType':'3','benchsci':true,'imageName':'tfs_9863_cells-10-00298-g001.jpg','benchSciPubmedId':'33535605'},{'sku':'15-0112-82','imageId':'853697','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_9861_gr4_lrg.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_9861_gr4_lrg.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_9861_gr4_lrg.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_9861_gr4_lrg.jpg?time\u003d20240507','sortOrder':'51','description':'Figure 4 Paquinimod rescues the mice infected by SARS-CoV-2 and MHV (A) A flow chart depicting the process of a drug rescue experiment. (B) Analysis of weight and survival rate of mice infected with SARS-CoV-2 and MHV after Paquinimod treatment. n \u003d 6. (C) Analysis of the rescue effect of Paquinimod by H\u0026E staining and pathology score of lung tissue in mice infected with SARS-CoV-2 or MHV at 5 dpi. Paquinimod treatment significantly prevented the bleeding and fibrosis in lung tissue. A number of pulmonary H\u0026E staining images were randomly selected for pathological scoring. n \u003d 10. Scale bars, 100 mum. (D) Immunohistochemical analysis of the S100A8 + cells in the lung tissue of mice infected with SARS-CoV-2 or MHV at 5 dpi after Paquinimod treatment. The S100A8 + cells in the lungs of mice infected with coronavirus were decreased significantly after Paquinimod treatment. The red arrows indicate the S100A8 + cells. n \u003d 5. Scale bars, 50 mum. (E) qRT-PCR analysis for the expression of S100a8 and Ly6g in the lung of mice infected with SARS-CoV-2 at 5 dpi after Paquinimod treatment. n \u003d 3. (F) qRT-PCR analysis of viral loads in the lungs of mice infected with coronavirus SARS-CoV-2 and MHV at 5 dpi after Paquinimod treatment. n \u003d 3. (G) Flow cytometry analysis of neutrophils in lungs, blood, and bone marrow from mice infected with SARS-CoV-2 at 5 dpi after Paquinimod treatment. CD45 + CD11b + Ly6G variable aberrant neutrophils (P2) in the mice infected with SARS-CoV-2 were signifi','shortDescription':'Figure 4 Paquinimod rescues the mice infected by SARS-CoV-2 and MHV (A) A flow chart depicting the process of a drug rescue experiment. (B) Analysis of weight and survival rate of mice infected with SARS-CoV-2 and MHV after Paquinimod treatment. n \u003d 6. (C) Analysis of the rescue effect of Paquinimod by H\u0026E staining and pathology score of lung tissue in mice infected with SARS-CoV-2 or MHV at 5 dpi. Paquinim... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Feb 10, 2021, 5:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Cell host \u0026 microbe','journalText':'Cell host \u0026 microbe 2021 - ','sourceType':'3','benchsci':true,'imageName':'tfs_9861_gr4_lrg.jpg','benchSciPubmedId':'33388094'},{'sku':'15-0112-82','imageId':'853645','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_9861_gr3_lrg.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_9861_gr3_lrg.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_9861_gr3_lrg.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_9861_gr3_lrg.jpg?time\u003d20240507','sortOrder':'52','description':'Figure 3 A group of immature aberrant neutrophils emerged in coronavirus-infected mice (A) Immunohistochemical analysis of the location and expression of S100A8 in the lung tissue of mice infected with SARS-CoV-2 or MHV at 5 dpi. The S100A8 + cells in the lungs of mice infected with coronavirus were increased significantly. The red arrows indicate the S100A8 + cells. n \u003d 5. Scale bars, 50 mum. (B) Flow cytometry analysis of neutrophils in lungs from mice infected with SARS-CoV-2 and MHV at 5 dpi. Control group means mice treated with vehicle. Gate P1 shows the conventional neutrophils (CD45 + CD11b + Ly6G high ), and Gate P2 shows the pathologic aberrant neutrophils (CD45 + CD11b + Ly6G variable ). Aberrant neutrophils (P2) in the lungs of mice infected with coronavirus were significantly increased. n \u003d 3. (C) Flow cytometry analysis of neutrophils in lungs of mice challenged with IAV, EMCV, HSV-1, and LPS at 5 dpi. The results showed that these treatments did not induce an increase in aberrant neutrophils. n \u003d 3. (D) Flow cytometry analysis of neutrophils in bone marrow from mice infected with SARS-CoV-2 and MHV at 5 dpi. n \u003d 3. (E) qRT-PCR-analyzed related gene expression of aberrant neutrophils in bone marrow of mice infected with MHV at 5 dpi and identified the differentiated types of aberrant neutrophils. n \u003d 3. *** p \u003c 0.001. Error bars, SD.','shortDescription':'Figure 3 A group of immature aberrant neutrophils emerged in coronavirus-infected mice (A) Immunohistochemical analysis of the location and expression of S100A8 in the lung tissue of mice infected with SARS-CoV-2 or MHV at 5 dpi. The S100A8 + cells in the lungs of mice infected with coronavirus were increased significantly. The red arrows indicate the S100A8 + cells. n \u003d 5. Scale bars, 50 mum. (B) Flow cyto... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Feb 10, 2021, 5:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Cell host \u0026 microbe','journalText':'Cell host \u0026 microbe 2021 - ','sourceType':'3','benchsci':true,'imageName':'tfs_9861_gr3_lrg.jpg','benchSciPubmedId':'33388094'},{'sku':'15-0112-82','imageId':'925896','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_14987_nihms-1640051-f0007.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_14987_nihms-1640051-f0007.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_14987_nihms-1640051-f0007.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_14987_nihms-1640051-f0007.jpg?time\u003d20240507','sortOrder':'53','description':'Figure 7: High levels of Hotairm1 in plasma exosomes and MDSCs from late septic patients. (A) Exosomes were purified from plasma and RNA was extracted using exoRNeasy Starter kit. (B) Peripheral blood CD33 + CD11b+HLA-DR - cells were isolated by magnetic cell separation. PBMCs were first purified and depleted of the HLA-DR + cells. The HLA-DR - cell population was then subjected to positive selection with biotin-coupled anti-CD33 antibody, followed by anti-CD11b antibody. Total RNA was extracted using TRIzol reagent. Levels of Hotairm1 were determined by RT-qPCR as in Figure 3 . Values in A were normalized to 18S RNA, and values in B were normalized to GAPDH RNA. Data are expressed as means +- SD of 7-9 subjects/group and are presented relative to HC (1-fold), * p \u003c 0.05, versus HC or early septic; ** p \u003c 0.05, versus late septic. HC, helthy control. (C) S100A9 accumulates in cytosol in CD33+CD11b+HLA-DR - cells during late sepsis. Cytoplasmic and nuclear proteins were extracted from CD33 + CD11b + HLA-DR - cells, and levels of S100A9 were determined by Western blot. The results are representative of two Western blots. (D) Hotairm1 binds S100A9 protein during late sepsis. Cell lysates were prepared from CD33 + CD11b + HLA-DR - cells isolated from late septic patients (n\u003d4) and immunoprecipitated with S100A9 or IgG antibody. S100A9 levels were determined by Western blot. RNA was extracted from S100A9 IP, and Hotairm1 levels were determined by RT-qPCR. Values were normalized to','shortDescription':'Figure 7: High levels of Hotairm1 in plasma exosomes and MDSCs from late septic patients. (A) Exosomes were purified from plasma and RNA was extracted using exoRNeasy Starter kit. (B) Peripheral blood CD33 + CD11b+HLA-DR - cells were isolated by magnetic cell separation. PBMCs were first purified and depleted of the HLA-DR + cells. The HLA-DR - cell population was then subjected to positive selection with b... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Aug 13, 2022, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Journal of clinical \u0026 cellular immunology','journalText':'Journal of clinical \u0026 cellular immunology 2022 - ','sourceType':'3','benchsci':true,'imageName':'tfs_14987_nihms-1640051-f0007.jpg','benchSciPubmedId':'33335790'},{'sku':'15-0112-82','imageId':'925836','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_14987_nihms-1640051-f0004.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_14987_nihms-1640051-f0004.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_14987_nihms-1640051-f0004.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_14987_nihms-1640051-f0004.jpg?time\u003d20240507','sortOrder':'54','description':'Figure 4: Knockdown of Hotairm1 in late sepsis MDSCs attenuates their immunosuppressive functions. Gr1 + CD11b + cells were isolated from the bone marrow of late septic mice by positive selection using anti-Gr1 antibody and magnetic beads. The cells were transfected with Hotairm1-specific or scramble siRNAs for 36 hr. (A) Effects of MDSCs on T cell proliferation and activation. CD4 + T cells were isolated from splenocytes of naive mice with anti-CD4 antibody and labeled with the fluorescent dye CFSE. The late sepsis Gr1 + CD11b + cells with Hotairm1 knockdown were then co-cultured (1:1 ratio). T cells were stimulated with anti-CD3 plus anti-CD28 antibodies (1 mug/ml each). After 3 days, the cells were harvested, and T cell proliferation and IFNU production were determined as in Figure 2 . (B and C) Effect of exosomes lacking Hotairm1 on T cells. Late sepsis Gr1 + CD11b + cells with Hotairm1 knockdown were cultured for 24 hr in serum-free media. Culture supernatants were harvested, and exosomes were purified using exoEasy Maxi kit. (B) Levels of Hotairm1 in exosomal RNA was determined by RT-qPCR. Values were normalized to 18S RNA. (C) Spleen CD4 + T cells were labeled and cultured with naive Gr1 + CD11b + cells (as described in Figure 2 ) in the presence of Hotairm1-lacking exosomes. T cell proliferation and IFNU production were measured as in A. Data are expressed as means +- SD of 5-6 mice/group from three experiments. * p \u003c 0.05.KD, knockdown.','shortDescription':'Figure 4: Knockdown of Hotairm1 in late sepsis MDSCs attenuates their immunosuppressive functions. Gr1 + CD11b + cells were isolated from the bone marrow of late septic mice by positive selection using anti-Gr1 antibody and magnetic beads. The cells were transfected with Hotairm1-specific or scramble siRNAs for 36 hr. (A) Effects of MDSCs on T cell proliferation and activation. CD4 + T cells were isolated f... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Aug 13, 2022, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Journal of clinical \u0026 cellular immunology','journalText':'Journal of clinical \u0026 cellular immunology 2022 - ','sourceType':'3','benchsci':true,'imageName':'tfs_14987_nihms-1640051-f0004.jpg','benchSciPubmedId':'33335790'},{'sku':'15-0112-82','imageId':'925856','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_14987_nihms-1640051-f0005.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_14987_nihms-1640051-f0005.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_14987_nihms-1640051-f0005.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_14987_nihms-1640051-f0005.jpg?time\u003d20240507','sortOrder':'55','description':'Figure 5: Hotairm1 binds to S100A9 in late sepsis MDSCs. Gr1 + CD11b + cells were isolated from the bone marrow of late septic mice using anti-Gr1 antibody and magnetic beads. (A) The cells (pooled from 2 mice) were treated with formaldehyde for reversible cross-linking of RNA-protein complexes. Cell lysates were prepared and immunoprecipitated with S100A9 or IgG antibody, and S100A9 levels were determined by western blot. The cross-linked RNA was extracted from the immunoprecipitated complexes using TRIzol reagent, and Hotairm1 levels were determined by standard PCR. (B) Hotairm1 knockdown relocalizes S100A9 in the cytosol. Late sepsis Gr1 + CD11b + cells were transfected with Hotairm1-specific or scramble siRNAs for 36 hr. Cytoplasmic and nuclear proteins were extracted, and levels of S100A9 were determined by Western blot. (C) Ectopic expression of Hotairm1 in early sepsis Gr1 + CD11b + cells moves S100A9 to the nucleus. The cells were transfected with Hotairm1 plasmid or a control vector for 24 hr. Cell lysates were prepared and immunoprecipitated with S100A9 or IgG antibody, and S100A9 levels were determined by Western blot. RNA was extracted from S100A9 IP and Hotairm1 levels were determined by RT-qPCR. Values were normalized to IgG IP samples and presented relative to vector. (D) Protein extracts were prepared, and levels of S100A9 were determined by Western blot. The results are representative of three experiments.','shortDescription':'Figure 5: Hotairm1 binds to S100A9 in late sepsis MDSCs. Gr1 + CD11b + cells were isolated from the bone marrow of late septic mice using anti-Gr1 antibody and magnetic beads. (A) The cells (pooled from 2 mice) were treated with formaldehyde for reversible cross-linking of RNA-protein complexes. Cell lysates were prepared and immunoprecipitated with S100A9 or IgG antibody, and S100A9 levels were determined ... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Aug 13, 2022, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Journal of clinical \u0026 cellular immunology','journalText':'Journal of clinical \u0026 cellular immunology 2022 - ','sourceType':'3','benchsci':true,'imageName':'tfs_14987_nihms-1640051-f0005.jpg','benchSciPubmedId':'33335790'},{'sku':'15-0112-82','imageId':'925816','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_14987_nihms-1640051-f0003.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_14987_nihms-1640051-f0003.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_14987_nihms-1640051-f0003.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_14987_nihms-1640051-f0003.jpg?time\u003d20240507','sortOrder':'56','description':'Figure 3: Hotairm1 expression is increased in late sepsis MDSCs. Gr1 + CD11b + cells were isolated from the bone marrow of sham and septic mice by positive selection using anti-Gr1 antibody and magnetic beads. (A) The cells were cultured for 24 hr in serum-free media. Exosomes were purified from the culture supernatants, and exosomal RNA was extracted with exoRNeasy Starter kit. Levels of Hotairm1 were determined by RT-qPCR using RT lncRNAqPCR Assay Primers (Qiagen). Values were normalized to 18S RNA. (B) Total RNA was isolated from Gr1 + CD11b + cells using TRIzol reagent, and levels of Hotaim1 were determined as in A. Values were normalized to GAPDH RNA. (C) Gr1 + CD11b + cells isolated from naive mice were cultured for 24 hr without or with exosomes (50 mug/well), purified from late sepsis MDSC culture. The cells were harvested, total RNA was extracted and levels of Hotairm1 were determined as in B. PCR was performed in duplicate. Data are presented relative to sham or media control (1-fold). Data in A and B are expressed as means +- SD of 6-9 mice/group from three experiments. Data in C are expressed as means +- SD of 7 cultures from two experiments. * p \u003c 0.05.','shortDescription':'Figure 3: Hotairm1 expression is increased in late sepsis MDSCs. Gr1 + CD11b + cells were isolated from the bone marrow of sham and septic mice by positive selection using anti-Gr1 antibody and magnetic beads. (A) The cells were cultured for 24 hr in serum-free media. Exosomes were purified from the culture supernatants, and exosomal RNA was extracted with exoRNeasy Starter kit. Levels of Hotairm1 were dete... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Aug 13, 2022, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Journal of clinical \u0026 cellular immunology','journalText':'Journal of clinical \u0026 cellular immunology 2022 - ','sourceType':'3','benchsci':true,'imageName':'tfs_14987_nihms-1640051-f0003.jpg','benchSciPubmedId':'33335790'},{'sku':'15-0112-82','imageId':'925876','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_14987_nihms-1640051-f0006.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_14987_nihms-1640051-f0006.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_14987_nihms-1640051-f0006.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_14987_nihms-1640051-f0006.jpg?time\u003d20240507','sortOrder':'57','description':'Figure 6: Overexpression of Hotairm1 in early sepsis Gr1 + CD11b + cells switches them to the immunosuppressive phenotype. Gr1 + CD11b + cells were isolated from the bone marrow of early septic mice using anti-Gr1 antibody and magnetic beads. The cells were transfected with Hotairm1 expression plasmid or an empty vector and cultured with 10 ng/ml of recombinant mouse IL-10. (A) After 24 hr, a portion of the cells was used for Hotairm1 expression measurement by RT-qPCR. The remainder of the cells were washed and stimulated with 1 mug/ml of of E. coli lipopolysaccharide (serotype 0111:B4; Sigma) for 24 hr. (B) The cells were harvested, lysed and analyzed for arginase activity. (C and D) Levels of IL-10 and TNFalpha in the culture supernatants were measured by ELISA. Data are expressed as means +- SD of 5-6 mice (5-6 cultures/group) from two experiments, * p \u003c 0.05.','shortDescription':'Figure 6: Overexpression of Hotairm1 in early sepsis Gr1 + CD11b + cells switches them to the immunosuppressive phenotype. Gr1 + CD11b + cells were isolated from the bone marrow of early septic mice using anti-Gr1 antibody and magnetic beads. The cells were transfected with Hotairm1 expression plasmid or an empty vector and cultured with 10 ng/ml of recombinant mouse IL-10. (A) After 24 hr, a portion of the... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Aug 13, 2022, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Journal of clinical \u0026 cellular immunology','journalText':'Journal of clinical \u0026 cellular immunology 2022 - ','sourceType':'3','benchsci':true,'imageName':'tfs_14987_nihms-1640051-f0006.jpg','benchSciPubmedId':'33335790'},{'sku':'15-0112-82','imageId':'925796','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_14987_nihms-1640051-f0001.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_14987_nihms-1640051-f0001.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_14987_nihms-1640051-f0001.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_14987_nihms-1640051-f0001.jpg?time\u003d20240507','sortOrder':'58','description':'Figure 1: Exosomes shed from late sepsis MDSCs inhibit LPS-induced secretion of S100A9 protein from early sepsis MDSCs. Gr1 + CD11b + cells were isolated from bone marrow of sham and septic mice by positive selection using anti-Gr1 antibody and magnetic beads. The cells were cultured for 24 hr in serum-free media. Culture supernatants were harvested, and exosomes were purified using exoEasy Maxi kit. Early sepsis Gr1 + CD11b + cells were cultured in 12-well plates with exosomes (50 mug/well) for 24 hr with or without 0.1 mug/ml of E. coli lipopolysaccharide (serotype 0111:B4; Sigma-Aldrich, St. Louis, MO). Levels of S100A9 protein in the culture super natants were measured by ELISA. Data are expressed as means +- SD of 6-8 mice (6-8 cultures/group) from three experiments. * p /** p \u003c 0.05, versus exosomes from sham or early sepsis.','shortDescription':'Figure 1: Exosomes shed from late sepsis MDSCs inhibit LPS-induced secretion of S100A9 protein from early sepsis MDSCs. Gr1 + CD11b + cells were isolated from bone marrow of sham and septic mice by positive selection using anti-Gr1 antibody and magnetic beads. The cells were cultured for 24 hr in serum-free media. Culture supernatants were harvested, and exosomes were purified using exoEasy Maxi kit. Early ... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Aug 13, 2022, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Journal of clinical \u0026 cellular immunology','journalText':'Journal of clinical \u0026 cellular immunology 2022 - ','sourceType':'3','benchsci':true,'imageName':'tfs_14987_nihms-1640051-f0001.jpg','benchSciPubmedId':'33335790'},{'sku':'15-0112-82','imageId':'925916','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_9936_biomedicines-08-00590-g001.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_9936_biomedicines-08-00590-g001.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_9936_biomedicines-08-00590-g001.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_9936_biomedicines-08-00590-g001.jpg?time\u003d20240507','sortOrder':'59','description':'Figure 1 Phenotype and characterization of HoxB8-Flt3 ligand (FL)-derived myeloid and lymphoid cells. ( A ) Scheme of hematopoietic progenitor cell (HPC) generation using retroviral ER-HoxB8, and differentiation into lymphoid and myeloid cells with indicated quality controls. The scheme was drawn using motifolio drawing toolkits (Copyright (c) motifolio.com; 3 September 2020). ( B ) Growth curve of HoxB8-FL cells (#1: wild-type, #2 Imu-HA-Bcl6 , #3 Cxcr4 WHIM ) with the specified differentiation factors, Estr: estradiol. Error bars represent the standard deviation of three HoxB8-FL cell populations. ( C ) Fluorescence-activated cell scanning (FACS) analysis of undifferentiated HoxB8-FL cells using c-kit expression when cultivated with the specified factors. ( D ) FACS analysis of CD11b and GR1 to identify dendritic cells and granulocytes. ( E ) Co-cultivation with OP9 feeder cells induces differentiation into CD19+/B220+ B cells. ( F ) Principal component analysis of transcriptome profiles of indicated cell lines. ( G ) Cluster analysis of indicated cell lines, based on their transcriptional profile. All biological replicates were performed as technical triplicates.','shortDescription':'Figure 1 Phenotype and characterization of HoxB8-Flt3 ligand (FL)-derived myeloid and lymphoid cells. ( A ) Scheme of hematopoietic progenitor cell (HPC) generation using retroviral ER-HoxB8, and differentiation into lymphoid and myeloid cells with indicated quality controls. The scheme was drawn using motifolio drawing toolkits (Copyright (c) motifolio.com; 3 September 2020). ( B ) Growth curve of HoxB8-FL... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Dec 9, 2020, 5:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Biomedicines','journalText':'Biomedicines 2020 - ','sourceType':'3','benchsci':true,'imageName':'tfs_9936_biomedicines-08-00590-g001.jpg','benchSciPubmedId':'33317212'},{'sku':'15-0112-82','imageId':'925140','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_14947_urn-x-wiley-07415400-media-jlb10762-jlb10762-fig-0002.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_14947_urn-x-wiley-07415400-media-jlb10762-jlb10762-fig-0002.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_14947_urn-x-wiley-07415400-media-jlb10762-jlb10762-fig-0002.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_14947_urn-x-wiley-07415400-media-jlb10762-jlb10762-fig-0002.jpg?time\u003d20240507','sortOrder':'60','description':'2 FIGURE CD11b + c-fms + Ly6C hi population accumulate in BM, SPL, and PB following Pg infection . (A) Representative flow cytometry plots and percentage of myeloid cell population in BM of Ctrl and Pg -infected mice. (B) Total cell numbers in BM of Ctrl and Pg -infected mice ( n \u003d 9 for Ctrl group and n \u003d 8 for Pg -infected group in A and B). (C) Representative flow cytometry plots and percentage of myeloid cell populations in SPL of Ctrl and Pg -infected mice. (D) Total cell numbers in SPL of Ctrl and Pg -infected mice ( n \u003d 8 for Ctrl group and n \u003d 7 for Pg -infected group in C and D). (E) Representative flow cytometry plots and percentage of myeloid cell populations in PB of Ctrl and Pg -infected mice. (F) Total cell numbers in PB of Ctrl and Pg -infected mice ( n \u003d 8 for Ctrl group and n \u003d 6 for Pg- infected group in E and F). Data are expressed as mean +- SD. * P \u003c 0.05, ** P \u003c 0.01, *** P \u003c 0.001','shortDescription':'2 FIGURE CD11b + c-fms + Ly6C hi population accumulate in BM, SPL, and PB following Pg infection . (A) Representative flow cytometry plots and percentage of myeloid cell population in BM of Ctrl and Pg -infected mice. (B) Total cell numbers in BM of Ctrl and Pg -infected mice ( n \u003d 9 for Ctrl group and n \u003d 8 for Pg -infected group in A and B). (C) Representative flow cytometry plots and percentage of myeloi... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Oct 1, 2020, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Journal of leukocyte biology','journalText':'Journal of leukocyte biology 2020 - ','sourceType':'3','benchsci':true,'imageName':'tfs_14947_urn-x-wiley-07415400-media-jlb10762-jlb10762-fig-0002.jpg','benchSciPubmedId':'33311847'},{'sku':'15-0112-82','imageId':'925200','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_14951_urn-x-wiley-00071188-media-bph15339-bph15339-fig-0005.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_14951_urn-x-wiley-00071188-media-bph15339-bph15339-fig-0005.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_14951_urn-x-wiley-00071188-media-bph15339-bph15339-fig-0005.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_14951_urn-x-wiley-00071188-media-bph15339-bph15339-fig-0005.jpg?time\u003d20240507','sortOrder':'61','description':'5 FIGURE Myeloid Pfkfb3 deficiency decreased macrophage infiltration into lungs. (a) Representative images and the quantification of the number of lung IMs and AMs from vehicle and 3PO-treated mice under normoxic or hypoxic (10% O 2 ) conditions. The cell subtypes were identified using flow cytometry defining IMs as CD45 + F4/80 int-hi CD11b high CD11c low and AMs as CD45 + F4/80 int-hi CD11c high CD11b low , n \u003d 5-7. (b) Representative images and quantification of the number of lung IMs and AMs from Pfkfb3 WT or Pfkfb3 DeltaMphi mice under normoxic or hypoxic (10% O 2 ) conditions, n \u003d 6. (c) Representative micrographs ( left ) and quantification of macrophages ( right ) in the lungs of Pfkfb3 WT or Pfkfb3 DeltaMphi mice exposed to normoxia or hypoxia (10% O 2 ) for 4 weeks. N \u003d 6. Sections were co-stained for F4/80 (red), alpha-SMA (green) and DAPI (blue). All data shown are means +- SEM. * P \u003c 0.05, significantly different as indicated; one-way ANOVA followed by Bonferroni test. ns, no significance','shortDescription':'5 FIGURE Myeloid Pfkfb3 deficiency decreased macrophage infiltration into lungs. (a) Representative images and the quantification of the number of lung IMs and AMs from vehicle and 3PO-treated mice under normoxic or hypoxic (10% O 2 ) conditions. The cell subtypes were identified using flow cytometry defining IMs as CD45 + F4/80 int-hi CD11b high CD11c low and AMs as CD45 + F4/80 int-hi CD11c high CD11b low... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Mar 1, 2021, 5:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'British journal of pharmacology','journalText':'British journal of pharmacology 2021 - ','sourceType':'3','benchsci':true,'imageName':'tfs_14951_urn-x-wiley-00071188-media-bph15339-bph15339-fig-0005.jpg','benchSciPubmedId':'33300142'},{'sku':'15-0112-82','imageId':'925080','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_14944_urn-x-wiley-08941491-media-glia23948-glia23948-fig-0001.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_14944_urn-x-wiley-08941491-media-glia23948-glia23948-fig-0001.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_14944_urn-x-wiley-08941491-media-glia23948-glia23948-fig-0001.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_14944_urn-x-wiley-08941491-media-glia23948-glia23948-fig-0001.jpg?time\u003d20240507','sortOrder':'62','description':'1 FIGURE The effects of postmortem delay (PMD) on viable fluorescence-activated cell sorting (FACS)-sorted mouse microglia numbers and RNA quality. (a) FACS plots depicting the sorting strategy of DAPI neg Ly6C neg CD11b high CD45 int microglia and the PMD induced decrease in the percentage of DAPI neg microglia in gate R5. (b) Dot plot depicting the number of DAPI neg microglia sorted from entire mouse brains at different PMD times ( n \u003d 4 mice per PMD). (c) Dot plot depicting RIN values of RNA extracted from sorted DAPI neg Ly6C neg CD11b high CD45 int microglia at different PMD times ( n \u003d 4 mice per PMD). A one-way ANOVA followed by a Bonferroni correction for multiple comparisons was performed to assess significance. **, p \u003c .01; ***, p \u003c .001','shortDescription':'1 FIGURE The effects of postmortem delay (PMD) on viable fluorescence-activated cell sorting (FACS)-sorted mouse microglia numbers and RNA quality. (a) FACS plots depicting the sorting strategy of DAPI neg Ly6C neg CD11b high CD45 int microglia and the PMD induced decrease in the percentage of DAPI neg microglia in gate R5. (b) Dot plot depicting the number of DAPI neg microglia sorted from entire mouse bra... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Apr 1, 2021, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Glia','journalText':'Glia 2021 - ','sourceType':'3','benchsci':true,'imageName':'tfs_14944_urn-x-wiley-08941491-media-glia23948-glia23948-fig-0001.jpg','benchSciPubmedId':'33296111'},{'sku':'15-0112-82','imageId':'853410','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_9858_41467_2020_19833_Fig3_HTML.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_9858_41467_2020_19833_Fig3_HTML.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_9858_41467_2020_19833_Fig3_HTML.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_9858_41467_2020_19833_Fig3_HTML.jpg?time\u003d20240507','sortOrder':'63','description':'Fig. 3 m1928z-CD40L CAR T cells stimulate tumor-resident CD11b-CD103- DN cDCs to proliferate, upregulate IRF8, and differentiate to cDC1s. a IRF8 expression in CD11b - CD103 - double-negative (DN) (orange), CD11b - CD103 + cDC1 (green), and CD11b + CD103 + cDC2 (blue) in the tumor of untreated A20.GL tumor-bearing mice. FMO, flow minus one. b - d Ki-67 and IRF8 expression shown as flow cytometry contour plots in CD11b - CD103 - DN cDCs in the tumor ( b ), spleen ( c ), and tumor-draining lymph nodes (tdLN) ( d ) of A20.GL tumor-bearing mice on day 7 after CAR T cell treatment. Percentage of Ki-67 + IRF8 + DN cDCs is summarized from two independent experiments ( n \u003d 7/group). e CD45.2 + A20.GL tumor-bearing mice were treated with 3 x 10 6 CAR T cells i.v. and CD45.2 + CD11b - CD103 - DN cDCs were isolated from the tumor on day 3 by FACS. Sorted CD45.2 + DN cells were cultured in vitro on a CD45.1 + bone-marrow stromal layer for 3 days and the percentage of CD11c + CD103 + cDC1s of all CD45.2 + cells was analyzed. Shown are representative contour plots and the quantification of the percentage of CD11c + CD103 + cDC1s. Each dot represents one in vitro culture. Data were collected from two independently performed experiments (m1928z, n \u003d 5; m1928z-CD40L, n \u003d 6). f , g Ki-67 expression shown as contour plots in CD11b - CD103 + cDC1s ( f ) and CD11b + CD103 - cDC2s ( g ) in the tumor of A20.GL tumor-bearing mice on day 7 after CAR T cell treatment. Percentage of Ki-67 + cells is su','shortDescription':'Fig. 3 m1928z-CD40L CAR T cells stimulate tumor-resident CD11b-CD103- DN cDCs to proliferate, upregulate IRF8, and differentiate to cDC1s. a IRF8 expression in CD11b - CD103 - double-negative (DN) (orange), CD11b - CD103 + cDC1 (green), and CD11b + CD103 + cDC2 (blue) in the tumor of untreated A20.GL tumor-bearing mice. FMO, flow minus one. b - d Ki-67 and IRF8 expression shown as flow cytometry contour plo... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Dec 2, 2020, 5:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Nature communications','journalText':'Nature communications 2020 - ','sourceType':'3','benchsci':true,'imageName':'tfs_9858_41467_2020_19833_Fig3_HTML.jpg','benchSciPubmedId':'33268774'},{'sku':'15-0112-82','imageId':'853583','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_9859_elife-60223-fig7.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_9859_elife-60223-fig7.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_9859_elife-60223-fig7.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_9859_elife-60223-fig7.jpg?time\u003d20240507','sortOrder':'64','description':'Figure 7. Macrophages \u0027eat\u0027 dying leukocytes in the injured nerve. ( A ) Cartoon of phagocyte with actin rich phagocytic cup eating a tdTom + apoptotic cell (AC). \u0027Eat me\u0027 signals displayed on the surface of AC allow direct or indirect recognition via engulfment receptors. Following engulfment by phagocytes, AC are digested in the phagolysosome. Cellular cholesterol levels are controlled by upregulation of specific efflux mechanisms. ( B ) scRNAseq dotplot analysis of \u0027don\u0027t eat me\u0027 molecules ( Cd47, Sirpa ) and bridging molecules prominently expressed across cell types in the d3 post-SNC nerve. Average gene expression and percentage of cells expressing the gene are shown. ( C ) scRNAseq dotplot analysis of engulfment receptors in the d3 post-SNC nerve. Average gene expression and percentage of cells expressing the gene are shown. ( D ) Flow cytometric analysis of dead cells accumulating in the d3 and d7 nerve (n \u003d 3 biological replicas per time point). Data are represented as mean +- SEM. ( E ) Parabiosis complex of WT (CD45.1) mouse with a (CD45.2) tdTom reporter mouse. ( F ) Flow cytometry dot plot showing tdTom + myeloid cells (CD45.2 + , CD11b + ) in the sciatic nerve of non-parabiotic (tdTom single) mice. ( G ) Flow cytometry dot plot showing tdTom + myeloid cells (CD11b + ) in the sciatic nerve of the WT CD45.1 parabiont. ( H ) Flow cytometry dot plot of CD11b + , tdTom + -gated cells from non-parabiotic (tdTom + single) mice, analyzed for CD45.1 and CD45.2 surface sta','shortDescription':'Figure 7. Macrophages \u0027eat\u0027 dying leukocytes in the injured nerve. ( A ) Cartoon of phagocyte with actin rich phagocytic cup eating a tdTom + apoptotic cell (AC). \u0027Eat me\u0027 signals displayed on the surface of AC allow direct or indirect recognition via engulfment receptors. Following engulfment by phagocytes, AC are digested in the phagolysosome. Cellular cholesterol levels are controlled by upregulation of ... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Dec 2, 2020, 5:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'eLife','journalText':'eLife 2020 - ','sourceType':'3','benchsci':true,'imageName':'tfs_9859_elife-60223-fig7.jpg','benchSciPubmedId':'33263277'},{'sku':'15-0112-82','imageId':'853449','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_9859_elife-60223-fig2.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_9859_elife-60223-fig2.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_9859_elife-60223-fig2.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_9859_elife-60223-fig2.jpg?time\u003d20240507','sortOrder':'65','description':'Figure 2. Immune cell profiles in axotomized DRGs. ( A ) Representative images of L4 DRG cross sections from naive mice, d1, d3, and d7 post-SNC. Macrophages were stained with anti-Iba1 and anti-F4/80. Neurons were stained with anti-NFH. Scale bar, 50 um. ( B ) Quantification of granulocytes per DRG detected by flow cytometry. For flow cytometry of DRGs, naive mice (n \u003d 14 biological replicates), d1 (n \u003d 3), d3 (n \u003d 5), and d7 (n \u003d 12) post-SNC mice were used. Granulocytes (CD45 + , CD11b + , Ly6G + ) per DRG are shown. ( C ) Quantification of Mo/Mac (CD45 + , CD11b + , CD11c - , Ly6G - ) per DRG. ( D ) Quantification of MoDC (CD45 + , CD11b + , CD11c + , Ly6G - ) per DRG. ( E ) Quantification of cDC (CD45 + , CD11b - , CD11c + , Ly6G - ) per DRG. ( F ) Quantification of lymphocytes (CD45+, CD11b - ) per DRG. ( G ) Composition of CD45 + leukocytes in lumbar DRGs identified by flow cytometry. Flow data are represented as mean cell number +- SEM. Each data point represents L3-L5 DRGs pooled from three to four animals (18-24 DRGs), biological replicates, n \u003d 3-14. Statistical analysis was performed in GraphPad Prism (v7) using one-way or two-way ANOVA with correction for multiple comparisons with Tukey\u0027s post-hoc test. For B-F, unpaired two-tailed t-test with Welch\u0027s correction. A p value \u003c 0.05 (*) was considered significant. p\u003c0.01 (**), p\u003c0.001 (***), and p\u003c0.0001 (****). ( H ) Western blots analysis of DRGs and sciatic nerves (SNs) prepared from sham operated mice and mice a','shortDescription':'Figure 2. Immune cell profiles in axotomized DRGs. ( A ) Representative images of L4 DRG cross sections from naive mice, d1, d3, and d7 post-SNC. Macrophages were stained with anti-Iba1 and anti-F4/80. Neurons were stained with anti-NFH. Scale bar, 50 um. ( B ) Quantification of granulocytes per DRG detected by flow cytometry. For flow cytometry of DRGs, naive mice (n \u003d 14 biological replicates), d1 (n \u003d 3)... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Dec 2, 2020, 5:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'eLife','journalText':'eLife 2020 - ','sourceType':'3','benchsci':true,'imageName':'tfs_9859_elife-60223-fig2.jpg','benchSciPubmedId':'33263277'},{'sku':'15-0112-82','imageId':'853533','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_9859_elife-60223-fig6.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_9859_elife-60223-fig6.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_9859_elife-60223-fig6.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_9859_elife-60223-fig6.jpg?time\u003d20240507','sortOrder':'66','description':'Figure 6. Macrophage subpopulation in the injured nerve are functionally distinct and localize to specific sites. ( A-E ) Feature plots of Adgre1 (F4/80), Aif1 (Iba1), Cd68 (Scavenger receptor class D) , Cx3cr1 (Fractalkine receptor), and CD209a (DC-SIGN) expression in the d3 post-SNC nerve. ( F ) scRNAseq dot plot analysis of transcription regulators (TRs) enriched in leukocytes. Average gene expression and percentage of cells expressing the TR are shown. ( G ) Violin plot of Ly6c2 (Ly6C) expression in immune cells of the d3 post-SNC nerve. ( H-K ) Flow cytometric analysis of sciatic nerve Mo/Mac (CD45 + , CD11b + , Ly6G - , CD11c - ) in naive mice, d1, d3, and d7 post-SNC mice. Mo/Mac maturation was assessed by Ly6C surface staining. ( L, M ) Quantification of Ly6C distribution on Mo/Mac in naive nerves and at different post-SNC time points (n \u003d 11 biological replicates per time point); ( L ) Percentile of Ly6C - , Ly6C int , and Ly6C hi Mo/Mac and ( M ) number of Ly6C - , Ly6C int , and Ly6C hi Mo/Mac. Flow data are represented as mean +- SEM. Statistical analysis was performed in GraphPad Prism (v7) using one-way or two-way ANOVA with correction for multiple comparisons with Tukey\u0027s post-hoc test. A p value \u003c 0.05 (*) was considered significant. p\u003c0.01 (**), p\u003c0.001 (***), and p\u003c0.0001 (****). ( N ) Feature plot showing Arg1 (Arginase-1) expression in the 3d post-SNC nerve. ( O-Q ) Longitudinal sciatic nerve sections of Arg1-YFP reporter mice, from naive mice ( O ), d3 (','shortDescription':'Figure 6. Macrophage subpopulation in the injured nerve are functionally distinct and localize to specific sites. ( A-E ) Feature plots of Adgre1 (F4/80), Aif1 (Iba1), Cd68 (Scavenger receptor class D) , Cx3cr1 (Fractalkine receptor), and CD209a (DC-SIGN) expression in the d3 post-SNC nerve. ( F ) scRNAseq dot plot analysis of transcription regulators (TRs) enriched in leukocytes. Average gene expression an... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Dec 2, 2020, 5:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'eLife','journalText':'eLife 2020 - ','sourceType':'3','benchsci':true,'imageName':'tfs_9859_elife-60223-fig6.jpg','benchSciPubmedId':'33263277'},{'sku':'15-0112-82','imageId':'853489','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_9859_elife-60223-fig3.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_9859_elife-60223-fig3.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_9859_elife-60223-fig3.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_9859_elife-60223-fig3.jpg?time\u003d20240507','sortOrder':'67','description':'Figure 3. Sciatic nerve injury triggers massive accumulation of hematogenous leukocytes in the injured nerve but not axotomized DRGs. ( A ) Parbiosis complex of a wildtype (WT) and a tdTomato (tdTom) mouse. Mice were surgically paired at postnatal day 56. The timeline of the experiment is shown. ( B ) Flow cytometric analysis of sciatic nerve trunks collected from non-parabiotic (single) tdTom mice, WT parabionts, and tdTom parabionts. Dotplot of live (CD11b + , tdTom + ) cells in the d3 post-SNC nerve. ( C ) Quantification of tdTom + myeloid cells in the 3d injured nerve of WT single mice (WT-S), WT parabiont (WT-para), tdTom parabiont (tdTom-para), and tdTom single (tdTom-S) mice. The fraction of tdTom + myeloid cells (CD45 + , CD11b + ), MoDC (CD45 + , CD11b + , CD11c + , Ly6G - ), and Mo/Mac (CD45 + , CD11b + , CD11c - , Ly6G - ) is shown. For quantification of tdTom + immune cells, nerves from the WT parabiont and the tdTom parabiont were harvested separately (three mice per data point) with n \u003d 2-3 biological replicates. Flow data are represented as fraction of tdTom + cells +- SEM. Statistical analysis was performed in GraphPad Prism (v8) using one-way ANOVA with correction for multiple comparisons with Tukey\u0027s post-hoc test. p value of \u003c 0.001 (***) and p\u003c0.0001 (****). ( D ) Longitudinal sciatic nerves sections of the WT parabiont at d7 post-SNC. The nerve crush site is marked with a white dotted line, proximal is to the left, distal to the right. Anti-F4/80 (green)','shortDescription':'Figure 3. Sciatic nerve injury triggers massive accumulation of hematogenous leukocytes in the injured nerve but not axotomized DRGs. ( A ) Parbiosis complex of a wildtype (WT) and a tdTomato (tdTom) mouse. Mice were surgically paired at postnatal day 56. The timeline of the experiment is shown. ( B ) Flow cytometric analysis of sciatic nerve trunks collected from non-parabiotic (single) tdTom mice, WT para... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Dec 2, 2020, 5:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'eLife','journalText':'eLife 2020 - ','sourceType':'3','benchsci':true,'imageName':'tfs_9859_elife-60223-fig3.jpg','benchSciPubmedId':'33263277'},{'sku':'15-0112-82','imageId':'853351','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_9857_41419_2020_3223_Fig3_HTML.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_9857_41419_2020_3223_Fig3_HTML.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_9857_41419_2020_3223_Fig3_HTML.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_9857_41419_2020_3223_Fig3_HTML.jpg?time\u003d20240507','sortOrder':'68','description':'Fig. 3 ZD55-IL-24 inhibits melanoma growth in B16-bearing immunocompetent mouse model mainly through the indirect pathway of inducing systemic antitumor immunity. A , B Changes of the immune-related cytokines in tumors treated with ZD55-IL-24. A Heat-map of the down-regulated immunosuppressive cytokines in Fig. 2 C . B Heat-map of the up-regulated immunostimulatory cytokines in Fig. 2 D . C - J Immunohistochemical analysis of immune cell infiltration in tumors, as well as recruitment and activation in spleens. Tumors and spleens resected from B16-bearing C57BL/6 mice receiving PBS or ZD55-IL-24 treatment indicated in Fig. 1 A were analyzed 2 days after the last injection by immunohistochemical staining. C Shown are representative images of tumor sections immunostained for CD8 (red, left panel), CD11b and Ly-6G (yellow, middle panel), and NK1.1 (red, right panel). D Quantification of the CD8 + cells in C ( n \u003d 11). E Quantification of the CD11b + Ly-6G + Ly-6C low neutrophils in C ( n \u003d 3). f Quantification of the NK1.1 + cells in c ( n \u003d 6). G Quantification of the CD8 + cells in H ( n \u003d 9). H Shown are representative images of spleen sections immunostained for CD8 (red, left panel), CD11b and Ly-6G (yellow, middle panel), and NK1.1 (red, right panel). I Quantification of the CD11b + Ly-6G + Ly-6C low neutrophils in H ( n \u003d 3). j Quantification of NK1.1 + cells in h ( n \u003d 9). Nuclei is counterstained with DAPI (blue). Data are mean +- SD. Scale bars, 300 um. Shown is one of t','shortDescription':'Fig. 3 ZD55-IL-24 inhibits melanoma growth in B16-bearing immunocompetent mouse model mainly through the indirect pathway of inducing systemic antitumor immunity. A , B Changes of the immune-related cytokines in tumors treated with ZD55-IL-24. A Heat-map of the down-regulated immunosuppressive cytokines in Fig. 2 C . B Heat-map of the up-regulated immunostimulatory cytokines in Fig. 2 D . C - J Immunohistoc... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Nov 30, 2020, 5:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Cell death \u0026 disease','journalText':'Cell death \u0026 disease 2020 - ','sourceType':'3','benchsci':true,'imageName':'tfs_9857_41419_2020_3223_Fig3_HTML.jpg','benchSciPubmedId':'33257647'},{'sku':'15-0112-82','imageId':'853281','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_9854_fimmu-11-574839-g001.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_9854_fimmu-11-574839-g001.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_9854_fimmu-11-574839-g001.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_9854_fimmu-11-574839-g001.jpg?time\u003d20240507','sortOrder':'69','description':'Figure 1 CD11b + Gr-1 + myeloid-derived suppressor cells (MDSCs) increase in the liver after sublethal acetaminophen (APAP) challenge. (A) Representative staining of CD11b + Gr-1 + cells. (B) The frequencies of CD11b + Gr-1 + cells in different compartments enumerated at 7 days or 14 days after APAP treatment. Naive control group was healthy mice without any treatment (n\u003d10-18 per group). *P \u003c 0.05, **P \u003c 0.01, ***P \u003c 0.001. Kruskal-Wallis test. (C) Absolute cell numbers of CD11b + Gr-1 + cells in the liver. *P \u003c 0.05, ***P \u003c 0.001, NS, no significance, Kruskal-Wallis test. (D) The suppressive abilities of CD11b + Gr-1 + cells sorted either from the liver or the spleen at 7 days after APAP pretreatment, Mann-Whitney test. Data were expressed as mean +- SD.','shortDescription':'Figure 1 CD11b + Gr-1 + myeloid-derived suppressor cells (MDSCs) increase in the liver after sublethal acetaminophen (APAP) challenge. (A) Representative staining of CD11b + Gr-1 + cells. (B) The frequencies of CD11b + Gr-1 + cells in different compartments enumerated at 7 days or 14 days after APAP treatment. Naive control group was healthy mice without any treatment (n\u003d10-18 per group). *P \u003c 0.05, **P \u003c 0... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Jun 15, 2021, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Frontiers in immunology','journalText':'Frontiers in immunology 2021 - ','sourceType':'3','benchsci':true,'imageName':'tfs_9854_fimmu-11-574839-g001.jpg','benchSciPubmedId':'33250891'},{'sku':'15-0112-82','imageId':'925756','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_14973_13287_2020_2014_Fig1_HTML.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_14973_13287_2020_2014_Fig1_HTML.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_14973_13287_2020_2014_Fig1_HTML.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_14973_13287_2020_2014_Fig1_HTML.jpg?time\u003d20240507','sortOrder':'70','description':'Fig. 1 Characterization of murine BMMSCs. a , b Flow cytometric analysis of the surface markers showed positive expression of CD29, CD90, CD105, CD146, and Sca-1, and negative expression of hematopoietic markers CD11b, CD34, and CD45. c Representative image of colony formation of murine BMMSCs. d Representative image of Oil Red O staining of murine BMMSCs. e Representative image of ALP staining of murine BMMSCs. f Representative image of Alizarin red staining of murine BMMSCs. Scale bar, 500 mum','shortDescription':'Fig. 1 Characterization of murine BMMSCs. a , b Flow cytometric analysis of the surface markers showed positive expression of CD29, CD90, CD105, CD146, and Sca-1, and negative expression of hematopoietic markers CD11b, CD34, and CD45. c Representative image of colony formation of murine BMMSCs. d Representative image of Oil Red O staining of murine BMMSCs. e Representative image of ALP staining of murine BM... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Nov 27, 2020, 5:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Stem cell research \u0026 therapy','journalText':'Stem cell research \u0026 therapy 2020 - ','sourceType':'3','benchsci':true,'imageName':'tfs_14973_13287_2020_2014_Fig1_HTML.jpg','benchSciPubmedId':'33246491'},{'sku':'15-0112-82','imageId':'853331','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_9856_cancers-12-03457-g003.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_9856_cancers-12-03457-g003.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_9856_cancers-12-03457-g003.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_9856_cancers-12-03457-g003.jpg?time\u003d20240507','sortOrder':'71','description':'Figure 3 Osteosarcoma cell-derived extracellular-vesicles (EVs) promote accumulation of bone marrow-derived cells in the lungs. ( A ) Schematic illustration of the experimental setup. Mice were treated with either PBS, 143-B EVs or SAOS-2 EVs (10 µg) 2 times a week for 3 weeks after which mice were euthanized. ( B ) Relative mRNA expression levels of integrin alpha M gene encoding CD11b ( Itgam ) in bulk lung RNA in mice of indicated treatment groups. Transcript levels are normalized to Gapdh and expressed as fold change relative to control mice. n \u003d 6, mice were pooled from two independent experiments indicated in red and black ( C ) Representative flow cytometric profile (left panel) and quantification (right panel) of CD11b + cells isolated from lungs of mice from indicated treatment groups; n \u003d 3 mice per group. ( D ) Representative immunofluorescence images (left panel) and quantification (right panel) of CD11b + cells (red) and nuclei (blue) in lungs of mice from indicated treatment groups. Scale bar, 500 um. (*, p \u003c 0.05, **, p \u003c 0.01, ***, p \u003d 0.0001, ****, p \u003c 0.0001, Bonferroni\u0027s one-way ANOVA test).','shortDescription':'Figure 3 Osteosarcoma cell-derived extracellular-vesicles (EVs) promote accumulation of bone marrow-derived cells in the lungs. ( A ) Schematic illustration of the experimental setup. Mice were treated with either PBS, 143-B EVs or SAOS-2 EVs (10 µg) 2 times a week for 3 weeks after which mice were euthanized. ( B ) Relative mRNA expression levels of integrin alpha M gene encoding CD11b ( Itgam ) in bulk lu... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Nov 20, 2020, 5:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Cancers','journalText':'Cancers 2020 - ','sourceType':'3','benchsci':true,'imageName':'tfs_9856_cancers-12-03457-g003.jpg','benchSciPubmedId':'33233625'},{'sku':'15-0112-82','imageId':'853783','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_9862_aging-12-104176-g004.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_9862_aging-12-104176-g004.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_9862_aging-12-104176-g004.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_9862_aging-12-104176-g004.jpg?time\u003d20240507','sortOrder':'72','description':'Figure 4 Atg7 deletion accelerates the aging of CD11b + Ly6G - myeloid cells. ( A ) Flow cytometric analysis of ROS levels of CD11b + Ly6G - cells with fluorescent DCFH-DA. Left, histogram for flow cytometric assessment of CD11b + Ly6G - cells; right, geometric mean fluorescence intensity (MFI) of DCFH-DA in CD11b + Ly6G - cells of wild-type mice and atg7-deleted mice. ( B ) Flow cytometric analysis of mitochondrial mass levels of CD11b + Ly6G - cells with florescent MitoTracker Deep Red. Left, histogram for the flow cytometric assessment of CD11b + Ly6G - cells; right, geometric MFI of MitoTracker Deep Red in CD11b + Ly6G - cells of wild-type and atg7-deleted mice. ( C ) Gene expression heatmap of cell death negative regulators. ( D ) Analysis of apoptosis in CD11b + Ly6G - cells of wild-type mice and Atg7-deleted mice by Annexin V and PI double staining. Left, representative flow cytometric measurement; right, statistical results from cytometric analysis. Early apoptosis, Annexin V + PI - ; late apoptosis, Annexin V + PI + (right)','shortDescription':'Figure 4 Atg7 deletion accelerates the aging of CD11b + Ly6G - myeloid cells. ( A ) Flow cytometric analysis of ROS levels of CD11b + Ly6G - cells with fluorescent DCFH-DA. Left, histogram for flow cytometric assessment of CD11b + Ly6G - cells; right, geometric mean fluorescence intensity (MFI) of DCFH-DA in CD11b + Ly6G - cells of wild-type mice and atg7-deleted mice. ( B ) Flow cytometric analysis of mito... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Nov 24, 2020, 5:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Aging','journalText':'Aging 2020 - ','sourceType':'3','benchsci':true,'imageName':'tfs_9862_aging-12-104176-g004.jpg','benchSciPubmedId':'33232280'},{'sku':'15-0112-82','imageId':'853763','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_9862_aging-12-104176-g003.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_9862_aging-12-104176-g003.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_9862_aging-12-104176-g003.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_9862_aging-12-104176-g003.jpg?time\u003d20240507','sortOrder':'73','description':'Figure 3 Atg7-deletion accumulated histone H3.1 protein with incorrect cytoplasmic localization in the bone marrow CD11b + Ly6G - myeloid cells. ( A , C ). Western blotting analysis of histone H3.1 in bone marrow cells. Gapdh or total histone H3 was used as a loading control. ( A ) Mononuclear cells; ( C ) CD11b + Ly6G - and CD11b + Ly6G + myeloid cells. ( B , D ) Flow cytometric analysis of protein level of histone H3.1 in bone marrow cells. ( B ) Analysis of histone H3.1 in CD11b - and CD11b + bone marrow cells. ( D ) Analysis of histone H3.1 in CD11b + Ly6G - and CD11b + Ly6G + myeloid cells. Right, scheme for analysis of histone H3.1 in bone marrow cells. Left, statistical analysis of histone H3.1 geometric mean fluorescence intensity (MFI) in bone marrow cells. ( E ) Western blotting analysis of histone H3.1 in cytoplasm and nucleus from mononuclear cells. ( F ). Confocal detection of histone H3.1 protein in CD11b + Ly6G - myeloid cells. ( G ) Ratio of geometric mean of H3K9/14/18Ac compared to H3.','shortDescription':'Figure 3 Atg7-deletion accumulated histone H3.1 protein with incorrect cytoplasmic localization in the bone marrow CD11b + Ly6G - myeloid cells. ( A , C ). Western blotting analysis of histone H3.1 in bone marrow cells. Gapdh or total histone H3 was used as a loading control. ( A ) Mononuclear cells; ( C ) CD11b + Ly6G - and CD11b + Ly6G + myeloid cells. ( B , D ) Flow cytometric analysis of protein level o... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Nov 24, 2020, 5:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Aging','journalText':'Aging 2020 - ','sourceType':'3','benchsci':true,'imageName':'tfs_9862_aging-12-104176-g003.jpg','benchSciPubmedId':'33232280'},{'sku':'15-0112-82','imageId':'853743','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_9862_aging-12-104176-g001.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_9862_aging-12-104176-g001.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_9862_aging-12-104176-g001.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_9862_aging-12-104176-g001.jpg?time\u003d20240507','sortOrder':'74','description':'Figure 1 Atg7 deletion diminishes the cellularity of bone marrow CD11b + myeloid cells. ( A - D ) Graphical and statistical analysis of CD11b and Ly6G by flow cytometry in the bone marrow cells of wild-type and Atg7 or Atg5 hematopoietic-specific deleted mice. ( A , C ) Number of CD11b + Ly6G - and CD11b + Ly6G + myeloid cells in the bone marrow of wild-type and Atg7 or Atg5-deleted mice. ( B , D ) Percentage of CD11b + Ly6G - and CD11b + Ly6G + myeloid cells in the bone marrow of wild-type and Atg7 or Atg5-deleted mice. ( E , F ) Percentage of CD11b + and CD11b - myeloid cells in the bone marrow of wild-type and Atg7 or Atg5-deleted mice. ( G , H ) Percentage of Ly6G + and Ly6G - myeloid cells in CD11b + myeloid cells from the bone marrow of wild-type and Atg7 or Atg5-deleted mice.','shortDescription':'Figure 1 Atg7 deletion diminishes the cellularity of bone marrow CD11b + myeloid cells. ( A - D ) Graphical and statistical analysis of CD11b and Ly6G by flow cytometry in the bone marrow cells of wild-type and Atg7 or Atg5 hematopoietic-specific deleted mice. ( A , C ) Number of CD11b + Ly6G - and CD11b + Ly6G + myeloid cells in the bone marrow of wild-type and Atg7 or Atg5-deleted mice. ( B , D ) Percenta... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Nov 24, 2020, 5:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Aging','journalText':'Aging 2020 - ','sourceType':'3','benchsci':true,'imageName':'tfs_9862_aging-12-104176-g001.jpg','benchSciPubmedId':'33232280'},{'sku':'15-0112-82','imageId':'988232','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_19023_fimmu-11-536442-g002.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_19023_fimmu-11-536442-g002.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_19023_fimmu-11-536442-g002.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_19023_fimmu-11-536442-g002.jpg?time\u003d20240507','sortOrder':'75','description':'Heterozygous deletion of A20 results in myeloid-biased hematopoiesis. (A) Outline of experiments utilizing WT (VavCre + or RosaCreER + ) and A20 +/- (A20 +/- VavCre + or A20 +/- RosaCreER + ) mice for colony progenitor function and PB analysis. (B) A20 mRNA expression by qRT-PCR in lineage negative BM (Lin- BM) cells from VavCre+ and A20+/-VavCre+ mice (n \u003d 3 mice per group). (C) A20 protein expression by immunoblotting in Lin- BM cells from VavCre+ and A20+/-VavCre+ mice (pooled from two mice). ( D ) Colony formation in methylcellulose of BM LSK cells isolated from WT RosaCreER + and A20 +/- RosaCreER + mice (treated with tamoxifen). One-tailed T test from three mice per group. (E) Complete blood counts for WT (VavCre + ; n \u003d 3) and heterozygous A20-deficient (A20 +/- VavCre + ; n \u003d 6) mice at the indicated time points post BM transplantation. *P \u003c 0.05. (F) Flow cytometric analysis of donor-derived (CD45.2 + ) myeloid cells (CD11b + ) in the PB from recipient mice reconstituted with BM from VavCre + (n \u003d 7) or A20 -/- VavCre + BM cells (n \u003d 7) (CD45.2 + ) at the indicated time points post-transplantation. (G) Flow cytometric analysis of donor-derived (CD45.2 + ) myeloid cells (CD11b + ) and lymphoid cells (CD3 + and B220 + ) in the PB from recipient mice reconstituted with BM from VavCre + or A20 -/- VavCre + BM cells (CD45.2 + ) at 16 weeks post-transplantation.','shortDescription':'Heterozygous deletion of A20 results in myeloid-biased hematopoiesis. (A) Outline of experiments utilizing WT (VavCre + or RosaCreER + ) and A20 +/- (A20 +/- VavCre + or A20 +/- RosaCreER + ) mice for colony progenitor function and PB analysis. (B) A20 mRNA expression by qRT-PCR in lineage negative BM (Lin- BM) cells from VavCre+ and A20+/-VavCre+ mice (n \u003d 3 mice per group). (C) A20 protein expression by i... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Apr 28, 2021, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Frontiers in immunology','journalText':'Frontiers in immunology 2021 - ','sourceType':'3','benchsci':true,'imageName':'tfs_19023_fimmu-11-536442-g002.jpg','benchSciPubmedId':'33224133'},{'sku':'15-0112-82','imageId':'925776','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_14974_jciinsight-5-135775-g143.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_14974_jciinsight-5-135775-g143.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_14974_jciinsight-5-135775-g143.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_14974_jciinsight-5-135775-g143.jpg?time\u003d20240507','sortOrder':'76','description':'Figure 5 Trophectoderm overexpression of Hyal-2 resulted in enhanced implantation rate but early embryonic lethality. Implantation sites were studied at E6.5, containing sham-infected embryos and embryos overexpressing Hyal-2 in their trophoblast. ( A ) H\u0026E staining ( n \u003d 6 dams; white arrows indicate decidua). ( B ) TUNEL staining revealed cell death at the embryonic niche of Hyal-2 OEx (white arrow indicate embryonic cells; n \u003d 4 dams). ( C and D ) Quantification of observed decidua, as well as their calculated area (2.9 +- 0.5; 4.75 +- 0.7; P \u003d 0.02) ( n \u003d 12 dams in control, n \u003d 10 dams in Hyal-2 OEx) divided by (3.42-fold change+- 0.07; 0.03; P \u003d 0.0006) ( n \u003d 8 dams, 27 implantation sites in control; n \u003d 6 dams, 23 implantation sites for Hyal-2 OEx). ( E and F ) Detection of MAC-2 + macrophages and their quantification (5.9-fold change +- 0.35; P \u003d 0.02) ( n \u003d 5 dams, 9 decidua in each group). ( G ) Presence of MAC-2 + macrophages was further demonstrated using immunostaining of macrophages in implantation sites harvested from surrogate mothers injected with rhodamine-labeled (ROX-labeled) lectin. Tissues were made transparent using modified tissue clearing procedure, thus enabling visualization of whole decidua by confocal microscopy. ( n \u003d 2 dams from each group). ( H ) Flow cytometry analysis of CD11b + F4/80 + cells in E6.5 decidua (12.33 +- 0.31 [control]; 17.02 +- 1.49 [overexpression]; P \u003d 0.04) ( n \u003d 3 dams in control, n \u003d 5 dams in Hyal-2 OEx). The statistical','shortDescription':'Figure 5 Trophectoderm overexpression of Hyal-2 resulted in enhanced implantation rate but early embryonic lethality. Implantation sites were studied at E6.5, containing sham-infected embryos and embryos overexpressing Hyal-2 in their trophoblast. ( A ) H\u0026E staining ( n \u003d 6 dams; white arrows indicate decidua). ( B ) TUNEL staining revealed cell death at the embryonic niche of Hyal-2 OEx (white arrow indica... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Nov 19, 2020, 5:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'JCI insight','journalText':'JCI insight 2020 - ','sourceType':'3','benchsci':true,'imageName':'tfs_14974_jciinsight-5-135775-g143.jpg','benchSciPubmedId':'33208556'},{'sku':'15-0112-82','imageId':'853604','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_9860_nihms-1651551-f0006.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_9860_nihms-1651551-f0006.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_9860_nihms-1651551-f0006.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_9860_nihms-1651551-f0006.jpg?time\u003d20240507','sortOrder':'77','description':'FIGURE 6. Lipin-1 contributes to efferocytosis. ( A ) WT and KO mice subjected to an excisional wound-healing model. Number of macrophages/dead cells was analyzed via flow cytometry. ( B ) BMDMs from WT and KO mice were subjected to a dual-label in vitro model of continuing efferocytosis, and percentage of macrophages (CD11b + and F4/80 + ) that took up an initial event (primary) and multiple apoptotic bodies (continuing) were analyzed via flow cytometry. WT, EKO ( C ), and KO ( D ) mice were subjected to a zymosan model of peritonitis followed by peritoneal injection of PHK26-labeled AC. Percentage of macrophages (CD11b + , F4/80 + , PKH26 + , and Ly6G - ) with labeled AC were analyzed via flow cytometry. Graphed data represent mean uptake with SEM. Student t test was used to analyze data. n \u003d 8-12. * p \u003c\u003d 0.5.','shortDescription':'FIGURE 6. Lipin-1 contributes to efferocytosis. ( A ) WT and KO mice subjected to an excisional wound-healing model. Number of macrophages/dead cells was analyzed via flow cytometry. ( B ) BMDMs from WT and KO mice were subjected to a dual-label in vitro model of continuing efferocytosis, and percentage of macrophages (CD11b + and F4/80 + ) that took up an initial event (primary) and multiple apoptotic bodi... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Oct 19, 2020, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'ImmunoHorizons','journalText':'ImmunoHorizons 2020 - ','sourceType':'3','benchsci':true,'imageName':'tfs_9860_nihms-1651551-f0006.jpg','benchSciPubmedId':'33077427'},{'sku':'15-0112-82','imageId':'853162','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_9851_fimmu-11-01856-g0002.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_9851_fimmu-11-01856-g0002.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_9851_fimmu-11-01856-g0002.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_9851_fimmu-11-01856-g0002.jpg?time\u003d20240507','sortOrder':'78','description':'Figure 2 Partial loss of PTPN2 increases cDC2 accumulation in skin and liver. (A) Representative flow cytometry plots for identification of CD11b + cDC1s (brown) and CD24 + cDC2s (green). (B) IRF4 and IRF8 expression in cDC1s and cDC2s. (C) Pie charts of the proportion of cDC1s and cDC2s across tissues in young (5-weeks-old) PTPN2 fl/fl (WT) and PTPN2 fl/fl x CD11c Cre (KO) mice. (D-F) Frequencies of cDC subset distribution in 5-weeks-old (D) , 13-weeks-old (E) , and 22-weeks-old (F) mice. Data are representative of two independent experiments with n \u003e\u003d 4 mice (C-F) . * p \u003c 0.05 [two-tailed Mann Whitney test (D-F) ]. Data are shown as mean +- s.d. (D-F) .','shortDescription':'Figure 2 Partial loss of PTPN2 increases cDC2 accumulation in skin and liver. (A) Representative flow cytometry plots for identification of CD11b + cDC1s (brown) and CD24 + cDC2s (green). (B) IRF4 and IRF8 expression in cDC1s and cDC2s. (C) Pie charts of the proportion of cDC1s and cDC2s across tissues in young (5-weeks-old) PTPN2 fl/fl (WT) and PTPN2 fl/fl x CD11c Cre (KO) mice. (D-F) Frequencies of cDC su... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Apr 12, 2021, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Frontiers in immunology','journalText':'Frontiers in immunology 2021 - ','sourceType':'3','benchsci':true,'imageName':'tfs_9851_fimmu-11-01856-g0002.jpg','benchSciPubmedId':'32973765'},{'sku':'15-0112-82','imageId':'839907','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_12509_41467_2020_18491_Fig2_HTML.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_12509_41467_2020_18491_Fig2_HTML.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_12509_41467_2020_18491_Fig2_HTML.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_12509_41467_2020_18491_Fig2_HTML.jpg?time\u003d20240507','sortOrder':'79','description':'Fig. 2 Gdpd3 maintains the self-renewal capacity of CML stem cells in vivo. a Survival rates of retro-CML-affected mice in a primary BMT experiment that received BCR-ABL1/EGFP-transduced LSK cells from either Gdpd3 +/+ mice (one male, one female) or Gdpd3 -/- mice (two females). Results shown are cumulative data obtained from two biologically independent experiments ( P -value, Log-rank non-parametric test). b The survival rate of second-round BMT recipient mice that received serial transplantation of BCR-ABL1/EGFP + CML-LSK cells (3 x 10 4 cells) isolated from either the Gdpd3 +/+ retro-CML-affected mice (14 females) or Gdpd3 -/- retro-CML-affected mice (15 females) as in a . Results shown are cumulative data obtained from three biologically independent experiments. Mouse survival was monitored for 90 days. ( P -value, Log-rank non-parametric test) c - f Absolute numbers of BCR-ABL1/EGFP + CML-LSK cells isolated from c , e BM of the two hind limbs and d , f spleen of Gdpd3 +/+ retro-CML-affected mice and Gdpd3 -/- retro-CML-affected mice after c , d a first-round or e , f second-round of serial BM transplantation. Data are the mean absolute numbers +- s.d. of BCR-ABL1/EGFP + LSK cells. n numbers in a - f indicate biologically independent mouse numbers. ( P -value, unpaired two-sided Student\u0027\u0027s t -test). (See also Supplementary Fig. 6). g , h Cell cycle distribution of CML-LSK cells in the spleen of Gdpd3 +/+ retro-CML-affected mice (three females) or Gdpd3 -/- retro-CML-affe','shortDescription':'Fig. 2 Gdpd3 maintains the self-renewal capacity of CML stem cells in vivo. a Survival rates of retro-CML-affected mice in a primary BMT experiment that received BCR-ABL1/EGFP-transduced LSK cells from either Gdpd3 +/+ mice (one male, one female) or Gdpd3 -/- mice (two females). Results shown are cumulative data obtained from two biologically independent experiments ( P -value, Log-rank non-parametric test)... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Sep 17, 2020, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Nature communications','journalText':'Nature communications 2020 - ','sourceType':'3','benchsci':true,'imageName':'tfs_12509_41467_2020_18491_Fig2_HTML.jpg','benchSciPubmedId':'32943626'},{'sku':'15-0112-82','imageId':'853261','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_9853_41598_2020_72181_Fig1_HTML.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_9853_41598_2020_72181_Fig1_HTML.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_9853_41598_2020_72181_Fig1_HTML.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_9853_41598_2020_72181_Fig1_HTML.jpg?time\u003d20240507','sortOrder':'80','description':'Figure 1 Flow-cytometric analysis of the wild-type adult cochlea indicates the presence of innate and adaptive immune cells. Panels shows the gating strategy for flow-cytometric analysis of the immune cells in control spleen ( A ) and cochleae ( B ) of C57BL/6J mice. A gate was first set from the forward-scatter versus side-scatter dot-plot of all events in the area that corresponded to the size and granularity of lymphocytes using a spleen as a reference. The cells in the lymphocyte gate were then plotted as forward scatter versus Live-Dead stain. The cells in the live gate were then examined in a plot comparing the forward-scatter width and side-scatter area; cells inside the gate were determined to be single cells (singlets). The cells within the singlet gate were then plotted as a histogram of CD45 expression. Live CD45 + cells in the sample were further analyzed for B, T, NK, and myeloid cells and myeloid cells were further gated for macrophages and neutrophils depending on their surface-markers as described in methods section. Representative dot-plots from control C57BL/6 mouse spleen ( C ) and cochlea ( D ) shows various CD45 + immune cells including B, T, NK, and myeloid cells, macrophages and neutrophils with their respective surface expression of B220, CD3e, NK1.1, CD11b, CX3CR1, and Ly6G respectively. The numbers on the dot-plots shows the percentages of cells gated in the corresponding dot-plot. The numbers showed in the plots for B, T, NK, and myeloid cells are p','shortDescription':'Figure 1 Flow-cytometric analysis of the wild-type adult cochlea indicates the presence of innate and adaptive immune cells. Panels shows the gating strategy for flow-cytometric analysis of the immune cells in control spleen ( A ) and cochleae ( B ) of C57BL/6J mice. A gate was first set from the forward-scatter versus side-scatter dot-plot of all events in the area that corresponded to the size and granula... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Sep 16, 2020, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Scientific reports','journalText':'Scientific reports 2020 - ','sourceType':'3','benchsci':true,'imageName':'tfs_9853_41598_2020_72181_Fig1_HTML.jpg','benchSciPubmedId':'32938973'},{'sku':'15-0112-82','imageId':'852504','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_9832_41467_2020_18039_Fig1_HTML.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_9832_41467_2020_18039_Fig1_HTML.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_9832_41467_2020_18039_Fig1_HTML.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_9832_41467_2020_18039_Fig1_HTML.jpg?time\u003d20240507','sortOrder':'81','description':'Fig. 1 Dendritic cells from old mice exhibit an activated phenotype and promote Th1 and Th17 T cell responses. Single cell suspensions of lymph nodes and spleens from old and young C57BL/6 mice were labeled with anti-CD11c, anti-CD11b, anti-MHC class II, anti-CD40, anti-CD80, and anti-CD86. a The frequency of CD11b + CD11c + DCs in lymph nodes ( p \u003d 0.0006) and spleens ( p \u003d 0.0023), and b the expression of costimulatory molecules (MHC-II: p \u003d 0.0005/CD40: p \u003c 0.0001/CD80: p \u003d 0.0035/CD86: p \u003d 0.0007) by splenic DCs were assessed by flow cytometry. c Proliferative capacities of CD4 + ( p \u003d 0.0079) and CD8 + T cells ( p \u003d 0.0079) co-cultured with DCs from old and young mice were determined using CFSE dilution and viability assessed using propidium iodide ( d ) CD4 + T cells from young mice were co-cultured with CD11b + CD11c + DCs isolated from young and old mice and ( e ) pro-inflammatory cytokine expression was assessed by flow cytometry (IL-17: p \u003d 0.0002/IFN-gamma: p \u003d 0.0013) and ELISA (Il-17: p \u003d 0.004/IFN-gamma: p \u003d 0.0079); ( n \u003d 7 biologically independent animals), results are representative of at least three independent experiments. Column plots display mean with standard deviation. Statistical significance was determined by using two-tailed Mann-Whitney-test. Asterisks indicate p values * p \u003c\u003d 0.05, ** p \u003c\u003d 0.01, and *** p \u003c\u003d 0.001, only significant values are shown. Source data are provided as a Source Data file.','shortDescription':'Fig. 1 Dendritic cells from old mice exhibit an activated phenotype and promote Th1 and Th17 T cell responses. Single cell suspensions of lymph nodes and spleens from old and young C57BL/6 mice were labeled with anti-CD11c, anti-CD11b, anti-MHC class II, anti-CD40, anti-CD80, and anti-CD86. a The frequency of CD11b + CD11c + DCs in lymph nodes ( p \u003d 0.0006) and spleens ( p \u003d 0.0023), and b the expression of... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Aug 27, 2020, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Nature communications','journalText':'Nature communications 2020 - ','sourceType':'3','benchsci':true,'imageName':'tfs_9832_41467_2020_18039_Fig1_HTML.jpg','benchSciPubmedId':'32855397'},{'sku':'15-0112-82','imageId':'851636','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_9817_jciinsight-5-136773-g165.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_9817_jciinsight-5-136773-g165.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_9817_jciinsight-5-136773-g165.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_9817_jciinsight-5-136773-g165.jpg?time\u003d20240507','sortOrder':'82','description':'Figure 1 Lymphocytes make up the main immune population within digested GCT. Viable single tumor cell suspension and PBMCs from healthy donors were analyzed using polychromatic flow cytometry and progressive gating strategy. ( A ) Representative staining with CD3, CD4, CD8, CD25, CD45, and FOXP3 used to quantify helper (CD4 + ), cytotoxic (CD8 + ), and regulatory (Tregs) (CD4 + CD25 + FOXP3 + ) T cells in a GCT sample. ( B-D ) Representative staining with CD11b, HLA-DR, CD11c, Lineage, CD14, CD15, and CD33 used to identify the myeloid populations in a GCT sample. Tumor-associated macrophages (TAMs)/monocytes were separated from DC based on CD14 expression ( C ). Myeloid-derived suppressor cells (MDSC) were separated as eMDSC based on Lineage, HLA-DR, CD11b, and CD33 markers ( B ), whereas PMN-MDSC were characterized as CD15 + CD14 - CD11b + ( D ). Proportions of tumor-infiltrating immune cells in GCT were quantified as percentage of total cell suspension. ( E ) Percentages of CD4 + T cells, CD8 + T cells, and Tregs compared with total tumor cell suspension. ( F ) Comparison of PD1-expressing T cells in the GCT vs. PBMCs. ( G ) CD8 + T cells/Tregs ratio in GCT vs. PBMCs. ( H ) Percentage of TAMs/monocytes, DC, PMN-MDSC, and eMDSC of total tumor cell suspension. Mean +- SEM is shown. Each dot represents a patient ( n \u003d 7) or healthy control PBMCs ( n \u003d 3).','shortDescription':'Figure 1 Lymphocytes make up the main immune population within digested GCT. Viable single tumor cell suspension and PBMCs from healthy donors were analyzed using polychromatic flow cytometry and progressive gating strategy. ( A ) Representative staining with CD3, CD4, CD8, CD25, CD45, and FOXP3 used to quantify helper (CD4 + ), cytotoxic (CD8 + ), and regulatory (Tregs) (CD4 + CD25 + FOXP3 + ) T cells in a... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Aug 20, 2020, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'JCI insight','journalText':'JCI insight 2020 - ','sourceType':'3','benchsci':true,'imageName':'tfs_9817_jciinsight-5-136773-g165.jpg','benchSciPubmedId':'32814714'},{'sku':'15-0112-82','imageId':'853225','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_9852_cancers-12-02083-g004.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_9852_cancers-12-02083-g004.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_9852_cancers-12-02083-g004.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_9852_cancers-12-02083-g004.jpg?time\u003d20240507','sortOrder':'83','description':'Figure 4 Population of CD11b + myeloid progenitor cells differentiate into SMA + stromal cells within tumors and in vitro. ( A ) Representative image of red fluorescent protein (RFP) + stromal cells in tumor from CCR2-RFP heterozygous SCID mouse. ( B ) RFP + SMA + double positive cells within tumor stroma. ( C ) CD11b + SMA + double positive cells within tumor stroma. ( D ) CD45 + CD11b + CD34+ myeloid progenitor cells in the mammary gland at 1.5 ( n \u003d 5 empty vector (EV), 7 CCL2) and 2.5 weeks ( n \u003d 5 EV, 7 CCL2) post-transplantation were quantified by flow cytometry. ( E ) CD45 + CD11b + CD34 + myeloid progenitor cells in the bone marrow at 1.5 weeks ( n \u003d 6 EV, 7 CCL2) and 2.5 weeks ( n \u003d 3 mice/group) post-transplantation were quantified by flow cytometry. ( F ) Representative brightfield image of colony formed by CD45 + CD11b + CD34 + myeloid progenitor cells isolated using fluorescence-activated cell sorting (FACS). ( G ) Colonies in culture co-stained with SMA and collagen I. Statistical differences determined by Mann-Whitney U test. Magnification bars \u003d 50 um.','shortDescription':'Figure 4 Population of CD11b + myeloid progenitor cells differentiate into SMA + stromal cells within tumors and in vitro. ( A ) Representative image of red fluorescent protein (RFP) + stromal cells in tumor from CCR2-RFP heterozygous SCID mouse. ( B ) RFP + SMA + double positive cells within tumor stroma. ( C ) CD11b + SMA + double positive cells within tumor stroma. ( D ) CD45 + CD11b + CD34+ myeloid prog... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Jul 28, 2020, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Cancers','journalText':'Cancers 2020 - ','sourceType':'3','benchsci':true,'imageName':'tfs_9852_cancers-12-02083-g004.jpg','benchSciPubmedId':'32731354'},{'sku':'15-0112-82','imageId':'853186','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_9852_cancers-12-02083-g002.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_9852_cancers-12-02083-g002.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_9852_cancers-12-02083-g002.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_9852_cancers-12-02083-g002.jpg?time\u003d20240507','sortOrder':'84','description':'Figure 2 Stromal CCL2 overexpression in mouse mammary glands leads to time-dependent changes in the developing tumor microenvironment. ( A ) Representative H\u0026E images of oncogenic epithelial cell growth at 1.5 and 2.5 weeks post-transplantation. ( B ) Percent area of F4/80 + macrophages in developing tumors at 1.5 and 2.5 weeks post-transplantation ( n \u003d 4 tumors/group; Student\u0027s t -test). ( C ) CD45 + CD11b + monocytes/macrophages in the mammary gland at 1.5 and 2.5 weeks post-transplantation were quantified by flow cytometry ( n \u003d 5 EV, 7 CCL2, Mann-Whitney U test). ( D ) Percent area of SMA + cells in developing tumors at 1.5 and 2.5 weeks post-transplantation ( n \u003d 4 tumors/group; Student\u0027s t -test). Magnification bars \u003d 50 um.','shortDescription':'Figure 2 Stromal CCL2 overexpression in mouse mammary glands leads to time-dependent changes in the developing tumor microenvironment. ( A ) Representative H\u0026E images of oncogenic epithelial cell growth at 1.5 and 2.5 weeks post-transplantation. ( B ) Percent area of F4/80 + macrophages in developing tumors at 1.5 and 2.5 weeks post-transplantation ( n \u003d 4 tumors/group; Student\u0027s t -test). ( C ) CD45 + CD11... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Jul 28, 2020, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Cancers','journalText':'Cancers 2020 - ','sourceType':'3','benchsci':true,'imageName':'tfs_9852_cancers-12-02083-g002.jpg','benchSciPubmedId':'32731354'},{'sku':'15-0112-82','imageId':'925736','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_14971_cells-09-01634-g005.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_14971_cells-09-01634-g005.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_14971_cells-09-01634-g005.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_14971_cells-09-01634-g005.jpg?time\u003d20240507','sortOrder':'85','description':'Figure 5 Effects of compounds 5 and 7 on in vivo chemotaxis of CD11b + Ly6G + , CD11b + F4/80 + and CD11b - CD3 + cells. ( A ) Neutrophil content of pouches from mice given a vehicle injection (top left), an LPS injection (top right), an LPS injection and compound 5 (bottom left) or an LPS injection and compound 7 (bottom right). Flow cytometry plots represent the distribution of live cells based on surface CD11b and Ly6G staining; ( B ) analysis of the percentage of neutrophils (CD11b+Ly6G+) recruited to air pouches; ( C ) total number of neutrophils (CD11b+Ly6G+) migrated to subdermal air pouches; ( D ) macrophage content of pouches from mice given a vehicle injection (top left), an LPS injection (top right), an LPS injection and compound 5 (bottom left) or an LPS injection and compound 7 (bottom right). Flow cytometry plots represent the distribution of live cells based on surface CD11b and F4/80 staining; ( E ) analysis of the percentage of macrophages (CD11b+F4/80+) recruited to air pouches. ( F ) Total number of macrophages (CD11b+F4/80+) migrated to subdermal air pouches. ( G ) Analysis of the percentage of T-cells (CD11b-CD3+) recruited to air pouches. ( H ) Total number of T-cells (CD11b-CD3+) migrated to subdermal air pouches. Air pouches contain compound 5 (5 ug) and compound 7 (5 ug) in the presence or absence of LPS (2 ug). Each data point represents a single mouse ( n \u003d 7-10). * p \u003c 0.05, ** p \u003c 0.01. Bars represent mean values. Data were pooled from three indep','shortDescription':'Figure 5 Effects of compounds 5 and 7 on in vivo chemotaxis of CD11b + Ly6G + , CD11b + F4/80 + and CD11b - CD3 + cells. ( A ) Neutrophil content of pouches from mice given a vehicle injection (top left), an LPS injection (top right), an LPS injection and compound 5 (bottom left) or an LPS injection and compound 7 (bottom right). Flow cytometry plots represent the distribution of live cells based on surface... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Jul 7, 2020, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Cells','journalText':'Cells 2020 - ','sourceType':'3','benchsci':true,'imageName':'tfs_14971_cells-09-01634-g005.jpg','benchSciPubmedId':'32645949'},{'sku':'15-0112-82','imageId':'850623','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_8339_fimmu-11-00787-g005.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_8339_fimmu-11-00787-g005.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_8339_fimmu-11-00787-g005.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_8339_fimmu-11-00787-g005.jpg?time\u003d20240507','sortOrder':'86','description':'FIGURE 5 Loss of lipin-1 does not alter systemic immune responses. (A) Splenocytes and (B) blood cells were stained with a panel of antibodies to quantify monocyte/macrophage and PMN populations. Myeloid populations were defined as CD45 + , CD3 - CD19 - CD11b + . PMNs were CD11b + Ly6g + and monocytes were CD11b + Ly6G - . Each dot represents an individual animal. Experiment was performed twice (mean +- SEM). (C) Cytometric bead arrays to quantify cytokine concentrations in serum taken from mice 2 days after wounding Each dot represents an individual animal. Experiment was performed twice (mean +- SEM).','shortDescription':'FIGURE 5 Loss of lipin-1 does not alter systemic immune responses. (A) Splenocytes and (B) blood cells were stained with a panel of antibodies to quantify monocyte/macrophage and PMN populations. Myeloid populations were defined as CD45 + , CD3 - CD19 - CD11b + . PMNs were CD11b + Ly6g + and monocytes were CD11b + Ly6G - . Each dot represents an individual animal. Experiment was performed twice (mean +- SEM... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Mar 29, 2021, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Frontiers in immunology','journalText':'Frontiers in immunology 2021 - ','sourceType':'3','benchsci':true,'imageName':'tfs_8339_fimmu-11-00787-g005.jpg','benchSciPubmedId':'32431707'},{'sku':'15-0112-82','imageId':'853127','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_9849_41419_2020_2546_Fig4_HTML.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_9849_41419_2020_2546_Fig4_HTML.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_9849_41419_2020_2546_Fig4_HTML.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_9849_41419_2020_2546_Fig4_HTML.jpg?time\u003d20240507','sortOrder':'87','description':'Fig. 4 cGAS-STING signaling is required for the pro-metastatic effect of irradiated MSCs. a MSCs were transfected with siRNA for 24 h and then cultured for another 24 h after irradiation (12 Gy). The expression levels of cGAS in MSCs were determined by real-time PCR. MSCs were transfected with siRNA for 24 h and then cultured for another 48 h after irradiation (12 Gy). The expression levels of cGAS were analyzed by western blotting. b MSCs were transfected with siRNA for 24 h and then cultured for another 24 h after irradiation (12 Gy). The expression levels of STING in MSCs were determined by real-time PCR. MSCs were transfected with siRNA for 24 h and then cultured for another 48 h after irradiation (12 Gy). The expression levels of STING were analyzed by western blotting. c , d MSCs transfected with sicGAS or siSTING for 24 h were cultured for another 24 h after irradiation (12 Gy). The expression level of Ccl5 was determined by qPCR. e , i MSCs (1 x 10 4 ) were transfected with siRNA for 24 h and then cultured for another 24 h after irradiation (12 Gy). These cells were co-injected with 4T1 cells (5 x 10 4 ) into BALB/c mice via tail vein. Metastatic nodules were counted after 14 days ( e ). Single-cell suspensions prepared from lung tissues were analyzed for the frequency of CD11b + F4/80 + macrophages ( f - g ), CD4 + T cells ( h ) and CD8 + T cells ( i ) by flow cytometry. n \u003e\u003d 3 for each group. All experiments in this figure were repeated at least three times. * p \u003c 0','shortDescription':'Fig. 4 cGAS-STING signaling is required for the pro-metastatic effect of irradiated MSCs. a MSCs were transfected with siRNA for 24 h and then cultured for another 24 h after irradiation (12 Gy). The expression levels of cGAS in MSCs were determined by real-time PCR. MSCs were transfected with siRNA for 24 h and then cultured for another 48 h after irradiation (12 Gy). The expression levels of cGAS were ana... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'May 7, 2020, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Cell death \u0026 disease','journalText':'Cell death \u0026 disease 2020 - ','sourceType':'3','benchsci':true,'imageName':'tfs_9849_41419_2020_2546_Fig4_HTML.jpg','benchSciPubmedId':'32382015'},{'sku':'15-0112-82','imageId':'925696','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_14970_cells-09-01106-g003.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_14970_cells-09-01106-g003.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_14970_cells-09-01106-g003.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_14970_cells-09-01106-g003.jpg?time\u003d20240507','sortOrder':'88','description':'Figure 3 Stronger anti-inflammatory changes in the composition of immune modulatory cells in CD62L -/- mice during steatohepatitis-inducing diets. ( A ) Serum aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels of wild type (WT) and CD62L -/- animals after chow, 4 weeks MCD or 24 weeks HFD treatment. (* p \u003c 0.05). ( B ) Total numbers of intrahepatic neutrophils were analysed by FACS. Cells were gated by FSC/SSC; duplets were excluded. Live/CD45 + , CD11b + /Ly6G + were regarded as neutrophils (* p \u003c 0.05). ( C ) Total cell numbers of intrahepatic CD11b + /F4/80 + cells were analysed by FACS. Cells were gated by FSC/SSC; duplets were excluded. Live/CD45 + , then gated on CD11b + and F4/80 + (** p \u003c 0.01). ( D ) Intrahepatic CD4 + /CTLA4 + T cells were analysed by FACS. CD4 + /CTLA4 + T cells were gated by FSC/SSC, duplets were excluded, Live/CD45 + , CD4 + /CTLA4 + . A statistical analysis of the amount of CD4 + /CTLA4 + cells of recorded CD45 + cells was performed. (* p \u003c 0.05, ** p \u003c 0.01). ( E ) Intrahepatic CD25 + /FoxP3 + cells were analysed by FACS. Cells were gated by FSC/SSC, duplets were excluded, Live/CD45 + , CD4 + , CD25 + /FoxP3 + . A statistical analysis of the percentage of CD25 + /FoxP3 + of recorded CD45 + cells was performed. Whole livers of chow, MCD and HFD fed WT and CD62L -/- mice were analysed for FoxP3 mRNA expression via RT-qPCR (** p \u003c 0.01, *** p \u003c 0,001) and values expressed as fold induction over the mean values obtained for','shortDescription':'Figure 3 Stronger anti-inflammatory changes in the composition of immune modulatory cells in CD62L -/- mice during steatohepatitis-inducing diets. ( A ) Serum aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels of wild type (WT) and CD62L -/- animals after chow, 4 weeks MCD or 24 weeks HFD treatment. (* p \u003c 0.05). ( B ) Total numbers of intrahepatic neutrophils were analysed by FACS. ... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Apr 29, 2020, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Cells','journalText':'Cells 2020 - ','sourceType':'3','benchsci':true,'imageName':'tfs_14970_cells-09-01106-g003.jpg','benchSciPubmedId':'32365632'},{'sku':'15-0112-82','imageId':'925716','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_14970_cells-09-01106-g006.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_14970_cells-09-01106-g006.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_14970_cells-09-01106-g006.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_14970_cells-09-01106-g006.jpg?time\u003d20240507','sortOrder':'89','description':'Figure 6 Therapeutic intervention with a CD62L blocking antibody results in dampened pro-inflammatory changes and stronger anti-oxidative stress responses in liver. ( A ) Representative H\u0026E images or ( B ) Oil Red O stains of livers from WT mice after 6 w MCD with or without peritoneal administration of an isotype control antibody or a CD62L blocking antibody from week 4-6 after MCD feeding (400x, scale bars 50 um). ( C ) Intrahepatic CD11b + /F4/80 + cells were analysed by FACS after 6 w MCD with or without peritoneal administration of an isotype control antibody or a CD62L blocking antibody from week 4-6 after MCD feeding. Cells were gated by FSC/SSC; duplets were excluded. Live/CD45+, then gated on CD11b + and F4/80 + (* p \u003c 0.05). Intrahepatic neutrophils were analysed by FACS in the same groups. Cells were gated by FSC/SSC; duplets were excluded. Live/CD45 + , CD11b + /Ly6G + were regarded as neutrophils (*** p \u003c 0.001). ( D ) Hepatic IL-6 and TNF-alpha, ( E ) Nrf and HO-1, ( F ) alpha-SMA and TGF-beta mRNA expression was analysed in the same groups via RT-qPCR. Values are expressed as fold induction over the mean values obtained for WT mice treated with MCD diet for 6 weeks (* p \u003c 0.05, ** p \u003c 0.01). All data are expressed as mean +- SEM ( n \u003d 4). All experiments were repeated at least twice.','shortDescription':'Figure 6 Therapeutic intervention with a CD62L blocking antibody results in dampened pro-inflammatory changes and stronger anti-oxidative stress responses in liver. ( A ) Representative H\u0026E images or ( B ) Oil Red O stains of livers from WT mice after 6 w MCD with or without peritoneal administration of an isotype control antibody or a CD62L blocking antibody from week 4-6 after MCD feeding (400x, scale bar... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Apr 29, 2020, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Cells','journalText':'Cells 2020 - ','sourceType':'3','benchsci':true,'imageName':'tfs_14970_cells-09-01106-g006.jpg','benchSciPubmedId':'32365632'},{'sku':'15-0112-82','imageId':'841333','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_12622_41598_2020_64158_Fig3_HTML.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_12622_41598_2020_64158_Fig3_HTML.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_12622_41598_2020_64158_Fig3_HTML.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_12622_41598_2020_64158_Fig3_HTML.jpg?time\u003d20240507','sortOrder':'90','description':'Figure 3 Physiological abundance of Ly6c Lo non-classical monocytes compared to Ly6c Hi classical monocytes in the late gestation fetal liver. ( a ) Ly6c Lo monocytes, Ly6c Hi monocytes, and other leukocyte populations were identified by flow cytometry. ( b,c ) The overall proportion of Cd45 + leukocytes is relatively low in the late gestational fetal liver (E17.5, n \u003d 11), then increases by day of birth (P0, n \u003d 9), and plateaus (P3, n \u003d 6; P7, n \u003d 9; P10, n \u003d 6; P14, n \u003d 7), whereas the proportion in the spleen stays relatively stable (P0, n \u003d 6; P3, n \u003d 6; P7, n \u003d 9; P10, n \u003d 6; P14, n \u003d 7. ( d,e ) Cd11b + monocytes were identified and are at their highest abundance of the Cd45 + leukocyte compartment in the late gestational liver (E17.5, n \u003d 11). They then decrease at birth (P0, n \u003d 6), rise again to a level that is between the two earlier time points (P3, n \u003d 6; P7, n \u003d 9), and then decrease to day of birth levels (P10, n \u003d 6; P14, n \u003d 4). In the spleen, Ly6c Lo non-classical monocytes remained low at birth and peaked at P7. (f-g) There is a physiological abundance of Ly6c Lo non-classical monocytes compared to Ly6c Hi classical monocytes at E17.5 in the liver that is not observed in the spleen (p-value % : \u003c0.0001 (****), p-value # : 0.0007 (***)). Data represent mean +/- SEM.','shortDescription':'Figure 3 Physiological abundance of Ly6c Lo non-classical monocytes compared to Ly6c Hi classical monocytes in the late gestation fetal liver. ( a ) Ly6c Lo monocytes, Ly6c Hi monocytes, and other leukocyte populations were identified by flow cytometry. ( b,c ) The overall proportion of Cd45 + leukocytes is relatively low in the late gestational fetal liver (E17.5, n \u003d 11), then increases by day of birth (P... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Apr 28, 2020, 4:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'Scientific reports','journalText':'Scientific reports 2020 - ','sourceType':'3','benchsci':true,'imageName':'tfs_12622_41598_2020_64158_Fig3_HTML.jpg','benchSciPubmedId':'32346042'},{'sku':'15-0112-82','imageId':'841298','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_12621_BMRI2020-5417201.009.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_12621_BMRI2020-5417201.009.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_12621_BMRI2020-5417201.009.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_12621_BMRI2020-5417201.009.jpg?time\u003d20240507','sortOrder':'91','description':'Figure 9 The count of MDSC and ratio of M-MDSC/G-MDSC in BMNC after fluid resuscitation by HES. #: compared to control, P \u003c 0.05; MDSC: myeloid-derived suppressor cell; M-MDSC: monocytic MDSC; G-MDSC: granulocytic/neutrophilic MDSC; BMNC: suspension and bone marrow nucleated cells; HES: hydroxyethyl starch.','shortDescription':'Figure 9 The count of MDSC and ratio of M-MDSC/G-MDSC in BMNC after fluid resuscitation by HES. #: compared to control, P \u003c 0.05; MDSC: myeloid-derived suppressor cell; M-MDSC: monocytic MDSC; G-MDSC: granulocytic/neutrophilic MDSC; BMNC: suspension and bone marrow nucleated cells; HES: hydroxyethyl starch.','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Dec 16, 2020, 5:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'BioMed research international','journalText':'BioMed research international 2020 - ','sourceType':'3','benchsci':true,'imageName':'tfs_12621_BMRI2020-5417201.009.jpg','benchSciPubmedId':'32258126'},{'sku':'15-0112-82','imageId':'841270','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_12621_BMRI2020-5417201.008.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_12621_BMRI2020-5417201.008.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_12621_BMRI2020-5417201.008.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_12621_BMRI2020-5417201.008.jpg?time\u003d20240507','sortOrder':'92','description':'Figure 8 The count of MDSC and ratio of M-MDSC/G-MDSC in BMNC after fluid resuscitation by HTS. #: compared to control, P \u003c 0.05; MDSC: myeloid-derived suppressor cell; M-MDSC: monocytic MDSC; G-MDSC: granulocytic/neutrophilic MDSC; BMNC: suspension and bone marrow nucleated cells; HTS: hypertonic saline.','shortDescription':'Figure 8 The count of MDSC and ratio of M-MDSC/G-MDSC in BMNC after fluid resuscitation by HTS. #: compared to control, P \u003c 0.05; MDSC: myeloid-derived suppressor cell; M-MDSC: monocytic MDSC; G-MDSC: granulocytic/neutrophilic MDSC; BMNC: suspension and bone marrow nucleated cells; HTS: hypertonic saline.','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Dec 16, 2020, 5:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'BioMed research international','journalText':'BioMed research international 2020 - ','sourceType':'3','benchsci':true,'imageName':'tfs_12621_BMRI2020-5417201.008.jpg','benchSciPubmedId':'32258126'},{'sku':'15-0112-82','imageId':'841229','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_12621_BMRI2020-5417201.007.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_12621_BMRI2020-5417201.007.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_12621_BMRI2020-5417201.007.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_12621_BMRI2020-5417201.007.jpg?time\u003d20240507','sortOrder':'93','description':'Figure 7 The count of MDSC and ratio of M-MDSC/G-MDSC in BMNC after fluid resuscitation by NS. #: compared to control, P \u003c 0.05; MDSC: myeloid-derived suppressor cell; M-MDSC: monocytic MDSC; G-MDSC: granulocytic/neutrophilic MDSC; BMNC: suspension and bone marrow nucleated cells; NS: normal saline.','shortDescription':'Figure 7 The count of MDSC and ratio of M-MDSC/G-MDSC in BMNC after fluid resuscitation by NS. #: compared to control, P \u003c 0.05; MDSC: myeloid-derived suppressor cell; M-MDSC: monocytic MDSC; G-MDSC: granulocytic/neutrophilic MDSC; BMNC: suspension and bone marrow nucleated cells; NS: normal saline.','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Dec 16, 2020, 5:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'BioMed research international','journalText':'BioMed research international 2020 - ','sourceType':'3','benchsci':true,'imageName':'tfs_12621_BMRI2020-5417201.007.jpg','benchSciPubmedId':'32258126'},{'sku':'15-0112-82','imageId':'841009','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_12621_BMRI2020-5417201.002.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_12621_BMRI2020-5417201.002.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_12621_BMRI2020-5417201.002.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_12621_BMRI2020-5417201.002.jpg?time\u003d20240507','sortOrder':'94','description':'Figure 2 The count of MDSC and ratio of M-MDSC/G-MDSC in PBNC after fluid resuscitation by HTS. #: compared to control, P \u003c 0.05; MDSC: myeloid-derived suppressor cell; M-MDSC: monocytic MDSC; G-MDSC: granulocytic/neutrophilic MDSC; PBNC: peripheral blood nucleated cells; HTS: hypertonic saline.','shortDescription':'Figure 2 The count of MDSC and ratio of M-MDSC/G-MDSC in PBNC after fluid resuscitation by HTS. #: compared to control, P \u003c 0.05; MDSC: myeloid-derived suppressor cell; M-MDSC: monocytic MDSC; G-MDSC: granulocytic/neutrophilic MDSC; PBNC: peripheral blood nucleated cells; HTS: hypertonic saline.','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Dec 16, 2020, 5:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'BioMed research international','journalText':'BioMed research international 2020 - ','sourceType':'3','benchsci':true,'imageName':'tfs_12621_BMRI2020-5417201.002.jpg','benchSciPubmedId':'32258126'},{'sku':'15-0112-82','imageId':'840965','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_12621_BMRI2020-5417201.001.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_12621_BMRI2020-5417201.001.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_12621_BMRI2020-5417201.001.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_12621_BMRI2020-5417201.001.jpg?time\u003d20240507','sortOrder':'95','description':'Figure 1 The count of MDSC and ratio of M-MDSC/G-MDSC in PBNC after fluid resuscitation by NS. #: compared to control, P \u003c 0.05; MDSC: myeloid-derived suppressor cell; M-MDSC: monocytic MDSC; G-MDSC: granulocytic/neutrophilic MDSC; PBNC: peripheral blood nucleated cells; NS: normal saline.','shortDescription':'Figure 1 The count of MDSC and ratio of M-MDSC/G-MDSC in PBNC after fluid resuscitation by NS. #: compared to control, P \u003c 0.05; MDSC: myeloid-derived suppressor cell; M-MDSC: monocytic MDSC; G-MDSC: granulocytic/neutrophilic MDSC; PBNC: peripheral blood nucleated cells; NS: normal saline.','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Dec 16, 2020, 5:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'BioMed research international','journalText':'BioMed research international 2020 - ','sourceType':'3','benchsci':true,'imageName':'tfs_12621_BMRI2020-5417201.001.jpg','benchSciPubmedId':'32258126'},{'sku':'15-0112-82','imageId':'841185','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_12621_BMRI2020-5417201.006.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_12621_BMRI2020-5417201.006.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_12621_BMRI2020-5417201.006.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_12621_BMRI2020-5417201.006.jpg?time\u003d20240507','sortOrder':'96','description':'Figure 6 The count of MDSC and ratio of M-MDSC/G-MDSC in the spleen after fluid resuscitation by HES. #: compared to control, P \u003c 0.05; MDSC: myeloid-derived suppressor cell; M-MDSC: monocytic MDSC; G-MDSC: granulocytic/neutrophilic MDSC; HES: hydroxyethyl starch.','shortDescription':'Figure 6 The count of MDSC and ratio of M-MDSC/G-MDSC in the spleen after fluid resuscitation by HES. #: compared to control, P \u003c 0.05; MDSC: myeloid-derived suppressor cell; M-MDSC: monocytic MDSC; G-MDSC: granulocytic/neutrophilic MDSC; HES: hydroxyethyl starch.','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Dec 16, 2020, 5:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'BioMed research international','journalText':'BioMed research international 2020 - ','sourceType':'3','benchsci':true,'imageName':'tfs_12621_BMRI2020-5417201.006.jpg','benchSciPubmedId':'32258126'},{'sku':'15-0112-82','imageId':'841141','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_12621_BMRI2020-5417201.005.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_12621_BMRI2020-5417201.005.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_12621_BMRI2020-5417201.005.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_12621_BMRI2020-5417201.005.jpg?time\u003d20240507','sortOrder':'97','description':'Figure 5 The count of MDSC and ratio of M-MDSC/G-MDSC in the spleen after fluid resuscitation by HTS. #: compared to control, P \u003c 0.05; MDSC: myeloid-derived suppressor cell; M-MDSC: monocytic MDSC; G-MDSC: granulocytic/neutrophilic MDSC; HTS: hypertonic saline.','shortDescription':'Figure 5 The count of MDSC and ratio of M-MDSC/G-MDSC in the spleen after fluid resuscitation by HTS. #: compared to control, P \u003c 0.05; MDSC: myeloid-derived suppressor cell; M-MDSC: monocytic MDSC; G-MDSC: granulocytic/neutrophilic MDSC; HTS: hypertonic saline.','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Dec 16, 2020, 5:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'BioMed research international','journalText':'BioMed research international 2020 - ','sourceType':'3','benchsci':true,'imageName':'tfs_12621_BMRI2020-5417201.005.jpg','benchSciPubmedId':'32258126'},{'sku':'15-0112-82','imageId':'841053','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_12621_BMRI2020-5417201.003.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_12621_BMRI2020-5417201.003.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_12621_BMRI2020-5417201.003.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_12621_BMRI2020-5417201.003.jpg?time\u003d20240507','sortOrder':'98','description':'Figure 3 The count of MDSC and ratio of M-MDSC/G-MDSC in PBNC after fluid resuscitation by HES. #: compared to control, P \u003c 0.05; M-MDSC: monocytic MDSC; G-MDSC: granulocytic/neutrophilic MDSC; PBNC: peripheral blood nucleated cells; HES: hydroxyethyl starch.','shortDescription':'Figure 3 The count of MDSC and ratio of M-MDSC/G-MDSC in PBNC after fluid resuscitation by HES. #: compared to control, P \u003c 0.05; M-MDSC: monocytic MDSC; G-MDSC: granulocytic/neutrophilic MDSC; PBNC: peripheral blood nucleated cells; HES: hydroxyethyl starch.','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Dec 16, 2020, 5:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'BioMed research international','journalText':'BioMed research international 2020 - ','sourceType':'3','benchsci':true,'imageName':'tfs_12621_BMRI2020-5417201.003.jpg','benchSciPubmedId':'32258126'},{'sku':'15-0112-82','imageId':'841097','imageUrl':'https://www.thermofisher.com/antibody/images/650/tfs_12621_BMRI2020-5417201.004.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/tfs_12621_BMRI2020-5417201.004.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/tfs_12621_BMRI2020-5417201.004.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/tfs_12621_BMRI2020-5417201.004.jpg?time\u003d20240507','sortOrder':'99','description':'Figure 4 The count of MDSC and ratio of M-MDSC/G-MDSC in the spleen after fluid resuscitation by NS. #: compared to control, P \u003c 0.05; MDSC: myeloid-derived suppressor cell; M-MDSC: monocytic MDSC; G-MDSC: granulocytic/neutrophilic MDSC; NS: normal saline.','shortDescription':'Figure 4 The count of MDSC and ratio of M-MDSC/G-MDSC in the spleen after fluid resuscitation by NS. #: compared to control, P \u003c 0.05; MDSC: myeloid-derived suppressor cell; M-MDSC: monocytic MDSC; G-MDSC: granulocytic/neutrophilic MDSC; NS: normal saline.','altTag':'CD11b Antibody in Flow Cytometry (Flow)','title':'CD11b Antibody (15-0112-82) in Flow','appAbv':'Flow','dateTime':'Dec 16, 2020, 5:00:00 AM','appName':'Flow Cytometry','type':'Published Figures','journalTitle':'BioMed research international','journalText':'BioMed research international 2020 - ','sourceType':'3','benchsci':true,'imageName':'tfs_12621_BMRI2020-5417201.004.jpg','benchSciPubmedId':'32258126'}],'Advanced Verification':[]}" image-displayed-id="'90781'" product-sub-type="'antibody_primary'" prod-type="'antibody'" page-type="PDP" product-id="'15-0112-82'"> <div class="tabs"> <ul class="nav nav-pills"> <li class="tab" onclick="window.THERMO_FISHER.inp.onTabClick(event, this)" data-tabname="Antibody Testing Data"> <a class="tab-text"> Antibody Testing Data (1) </a> </li> <li class="tab" onclick="window.THERMO_FISHER.inp.onTabClick(event, this)" data-tabname="Published Figures"> <a class="tab-text"> Published Figures (98) </a> </li> </ul> <div gallery-flt class="gal-flt" is-with-abbr="true" enable-mobile-flt="true" mobile-result-count="true" filter-data="$ctrl.applicationsList" advanced-filter-data="$ctrl.advancedApplicationsList" filter-text="Application" event-name="{{$ctrl.fltAppEvent}}"> </div> </div> <div class="cntnt" ng-swipe-right="$ctrl.clickLeftArrow()" ng-swipe-left="$ctrl.clickRightArrow()"> <div class="nav-arrow" ng-if="!$ctrl.isMobileSmallTabletScreen()" onclick="window.THERMO_FISHER.inp.onClickOfLeftArrow(event, this)"> <div tabindex="0" class="gallery-left-arrows icon-gallery-arrow-left" > </div> </div> <div class="media-text"> <div class="media-display-mobile" ng-if="$ctrl.isMobileSmallTabletScreen()"> <div class="nav-arrow" onclick="window.THERMO_FISHER.inp.onClickOfLeftArrow(event, this)"> <div tabindex="0" class="gallery-left-arrows icon-gallery-arrow-left" > </div> </div> <div class="media-display"> <img id="media-image" class="image" ng-show="!$ctrl.isVideo" src="https://www.thermofisher.com/antibody/images/650/15-0112-82_CD11b_Flow_1-20170119083539.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody in Flow Cytometry (Flow)" longdesc="https://www.thermofisher.com/antibody/images/650/15-0112-82_CD11b_Flow_1-20170119083539.jpg?time=20240507?time=20240507" onerror="javascript:imageErrorHandler.call(this, event);" > <div class="hover-text" ng-show="!$ctrl.isVideo"> <a href="javascript:return false;" onclick="window.THERMO_FISHER.inp.openImageGalleryModal(event, this)" aria-label="image-link"> <div class="rectangle"> <div class="expand-logo-rightcorner"> <?xml version="1.0" encoding="utf-8"?>  <svg width="19px" height="19px" version="1.1" id="Layer_1" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink" x="0px" y="0px" viewBox="0 0 22 22" style="enable-background:new 0 0 22 22;" xml:space="preserve"> <style type="text/css"> .st0{fill-rule:evenodd;clip-rule:evenodd;fill:#222222;} </style> <title>Group 53</title> <desc>Created with Sketch.</desc> <g id="Symbols"> <g id="rollover-expand-icon" transform="translate(-8.000000, -8.000000)"> <g id="Group-48"> <g id="Group-53" transform="translate(8.000000, 8.000000)"> <g id="Group-49" transform="translate(0.000000, 0.000000)"> <g id="Group-54"> <g id="Group-55" transform="translate(0.000000, -0.000000)"> <path id="Fill-1" class="st0" d="M21.9,14.6h-2.2c0,1,0,1.9,0,2.9c0,0.2,0,0.4,0,0.6c-0.1-0.1-0.2-0.2-0.3-0.2 c-1.3-1.3-2.7-2.7-4-4l-1.6,1.5c1.3,1.4,2.7,2.7,4,4.1c0.1,0.1,0.1,0.2,0.3,0.3c-0.2,0-0.3,0-0.4,0c-1,0-2.1,0-3.1,0V22 c2.3,0,4.8,0,7.1,0.1c0.1,0,0.2,0,0.3,0c0-0.5-0.1-0.9-0.1-1.3C21.9,18.7,21.9,16.6,21.9,14.6z"/> <path id="Fill-4" class="st0" d="M1.3,21.9c1.9,0,4,0,6,0v-2.2c-1,0-1.9,0-2.9,0c-0.2,0-0.4,0-0.6,0C3.9,19.6,4,19.5,4,19.4 c1.3-1.3,2.7-2.7,3.9-4l-1.5-1.6c-1.3,1.3-2.7,2.7-4,4c-0.1,0.1-0.2,0.1-0.3,0.3c0-0.2,0-0.3,0-0.4c0-1,0-2.1,0-3.1h-2.2 c0,2.3,0,4.7-0.1,7c0,0.1,0,0.2,0,0.3C0.5,21.9,0.9,21.9,1.3,21.9"/> <path id="Fill-7" class="st0" d="M0.1,1.3c0,1.9,0,4,0,6h2.2c0-1,0-1.9,0-2.9c0-0.2,0-0.4,0-0.6C2.4,3.9,2.5,4,2.5,4.1 c1.3,1.3,2.7,2.7,4,3.9l1.6-1.5c-1.3-1.3-2.7-2.7-4-4C4,2.4,3.9,2.3,3.8,2.2c0.2,0,0.3,0,0.4,0c1,0,2.1,0,3.1,0V0 C5,0,2.6,0,0.3,0C0.2,0,0.1,0,0,0C0,0.5,0.1,0.9,0.1,1.3"/> <path id="Fill-10" class="st0" d="M20.7,0.1c-1.9,0-4,0-6,0v2.1c1,0,1.9,0,2.9,0c0.2,0,0.4,0,0.6,0C18,2.4,18,2.5,17.9,2.6 c-1.3,1.3-2.7,2.6-3.9,3.9L15.5,8c1.3-1.3,2.7-2.6,4-4c0.1-0.1,0.2-0.1,0.3-0.2c0,0.2,0,0.3,0,0.4c0,1,0,2,0,3.1H22 c0-2.3,0-4.7,0.1-6.9c0-0.1,0-0.2,0-0.3C21.5,0.1,21.1,0.1,20.7,0.1"/> </g> </g> </g> </g> </g> </g> </g> </svg> </div> </div> </a> </div> </div> <div class="nav-arrow" onclick="window.THERMO_FISHER.inp.onClickOfRightArrow(event, this)"> <div tabindex="0" class="gallery-right-arrows icon-gallery-arrow-right"> </div> </div> </div> <div class="media-display" ng-if="!$ctrl.isMobileSmallTabletScreen()"> <img id="media-image" class="image" ng-show="!$ctrl.isVideo" src="https://www.thermofisher.com/antibody/images/650/15-0112-82_CD11b_Flow_1-20170119083539.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody in Flow Cytometry (Flow)" longdesc="https://www.thermofisher.com/antibody/images/650/15-0112-82_CD11b_Flow_1-20170119083539.jpg?time=20240507?time=20240507" onerror="javascript:imageErrorHandler.call(this, event);" > <div class="hover-text" ng-show="!$ctrl.isVideo"> <a href="javascript:return false;" onclick="window.THERMO_FISHER.inp.openImageGalleryModal(event, this)" aria-label="image-link"> <div class="rectangle"> <div class="expand-logo-rightcorner"> <?xml version="1.0" encoding="utf-8"?>  <svg width="19px" height="19px" version="1.1" id="Layer_1" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink" x="0px" y="0px" viewBox="0 0 22 22" style="enable-background:new 0 0 22 22;" xml:space="preserve"> <style type="text/css"> .st0{fill-rule:evenodd;clip-rule:evenodd;fill:#222222;} </style> <title>Group 53</title> <desc>Created with Sketch.</desc> <g id="Symbols"> <g id="rollover-expand-icon" transform="translate(-8.000000, -8.000000)"> <g id="Group-48"> <g id="Group-53" transform="translate(8.000000, 8.000000)"> <g id="Group-49" transform="translate(0.000000, 0.000000)"> <g id="Group-54"> <g id="Group-55" transform="translate(0.000000, -0.000000)"> <path id="Fill-1" class="st0" d="M21.9,14.6h-2.2c0,1,0,1.9,0,2.9c0,0.2,0,0.4,0,0.6c-0.1-0.1-0.2-0.2-0.3-0.2 c-1.3-1.3-2.7-2.7-4-4l-1.6,1.5c1.3,1.4,2.7,2.7,4,4.1c0.1,0.1,0.1,0.2,0.3,0.3c-0.2,0-0.3,0-0.4,0c-1,0-2.1,0-3.1,0V22 c2.3,0,4.8,0,7.1,0.1c0.1,0,0.2,0,0.3,0c0-0.5-0.1-0.9-0.1-1.3C21.9,18.7,21.9,16.6,21.9,14.6z"/> <path id="Fill-4" class="st0" d="M1.3,21.9c1.9,0,4,0,6,0v-2.2c-1,0-1.9,0-2.9,0c-0.2,0-0.4,0-0.6,0C3.9,19.6,4,19.5,4,19.4 c1.3-1.3,2.7-2.7,3.9-4l-1.5-1.6c-1.3,1.3-2.7,2.7-4,4c-0.1,0.1-0.2,0.1-0.3,0.3c0-0.2,0-0.3,0-0.4c0-1,0-2.1,0-3.1h-2.2 c0,2.3,0,4.7-0.1,7c0,0.1,0,0.2,0,0.3C0.5,21.9,0.9,21.9,1.3,21.9"/> <path id="Fill-7" class="st0" d="M0.1,1.3c0,1.9,0,4,0,6h2.2c0-1,0-1.9,0-2.9c0-0.2,0-0.4,0-0.6C2.4,3.9,2.5,4,2.5,4.1 c1.3,1.3,2.7,2.7,4,3.9l1.6-1.5c-1.3-1.3-2.7-2.7-4-4C4,2.4,3.9,2.3,3.8,2.2c0.2,0,0.3,0,0.4,0c1,0,2.1,0,3.1,0V0 C5,0,2.6,0,0.3,0C0.2,0,0.1,0,0,0C0,0.5,0.1,0.9,0.1,1.3"/> <path id="Fill-10" class="st0" d="M20.7,0.1c-1.9,0-4,0-6,0v2.1c1,0,1.9,0,2.9,0c0.2,0,0.4,0,0.6,0C18,2.4,18,2.5,17.9,2.6 c-1.3,1.3-2.7,2.6-3.9,3.9L15.5,8c1.3-1.3,2.7-2.6,4-4c0.1-0.1,0.2-0.1,0.3-0.2c0,0.2,0,0.3,0,0.4c0,1,0,2,0,3.1H22 c0-2.3,0-4.7,0.1-6.9c0-0.1,0-0.2,0-0.3C21.5,0.1,21.1,0.1,20.7,0.1"/> </g> </g> </g> </g> </g> </g> </g> </svg> </div> </div> </a> </div> </div> <div class="media-desc"> <div class="gallery-count"> <p> FIGURE: <span class="current-img"> 1 </span> / <span class="img-total-count"> 99</span></p> </div> <div class = "verification-certificate hide" > <span class="icon-certification"></span> <span class="adv-cert-text">{{ $ctrl.currentElement.advancedVerification.fullName }}</span> <div class="cert-provider">{{ $ctrl.currentElement.advancedVerification.text }}</div> </div> <h2 class="product-name" ng-show="!$ctrl.isVideo"> CD11b Antibody (15-0112-82) in Flow </h2> <div ng-show="!$ctrl.isVideo"> <div class="image-desc"> <div class="product-desc-text viewing-more-long-description"> <span class="image-journal-text" > </span> <span class="short-desc"> Staining of mouse bone marrow cells with 0.06 µg of Rat IgG2b K Isotype Control PE-Cyanine5 (Product # 15-4031-82) (blue histogram) or 0.06 µg of Anti-Mouse CD11b PE-Cyanine5 (purple histogram).Cells in the large scatter population were used for analysis. </span> <span class="verification-info hide" ng-if="$ctrl.hasVerificationMethod"> <a rel="nofollow" ng-href="{{$ctrl.currentElement.advancedVerification.uri}}" >{{ $ctrl.currentElement.advancedVerification.fullName }} validation info.</a> </span> <a href="#" class="images-view-more-text hide" ng-if="$ctrl.showViewMore" onclick="window.THERMO_FISHER.inp.openImageGalleryModal(event, this)"> View more </a> </div> </div> <div class="img-desc-footer"> <div class="benchsci-pubmed-footer"> <div ng-cloak ng-if="$ctrl.currentElement.benchsci || $ctrl.sourceType === '3'" class="images-benchsci-footer"> <div class="images-benchsci-link" tabindex="0"> <span>Published figure supplied by</span> <span class="icon-benchsci-logo"> <svg id="Layer_1" data-name="Layer 1" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 89.75 23.21"><defs><style>.cls-1{fill:#222222;}</style></defs><title>benchsci-logo</title><g id="logo-blue-copy-3"><g id="logo-blue-copy-2"><path id="path14" class="cls-1" d="M34.54,11.49a2.45,2.45,0,0,0,1.59-2.34c0-1.69-1.21-2.94-3.32-2.94H28.88v10.9h4.21a3.06,3.06,0,0,0,3.37-3A2.57,2.57,0,0,0,34.54,11.49ZM31,8h1.49c1,0,1.57.53,1.57,1.36a1.36,1.36,0,0,1-1.55,1.37H31Zm1.72,7.35H31V12.47h1.75a1.42,1.42,0,0,1,1.62,1.46C34.34,14.79,33.72,15.34,32.69,15.34Z"/><path id="path16" class="cls-1" d="M41.34,9.32a3.8,3.8,0,0,0-3.72,4,3.83,3.83,0,0,0,3.91,4.05A3.39,3.39,0,0,0,45,15l-1.71-.51a1.67,1.67,0,0,1-1.72,1.15,1.85,1.85,0,0,1-1.91-1.73H45s0-.34,0-.63C45.09,10.81,43.69,9.32,41.34,9.32Zm-1.66,3.15A1.63,1.63,0,0,1,41.37,11a1.52,1.52,0,0,1,1.69,1.49Z"/><path id="path18" class="cls-1" d="M50.58,9.35a2.48,2.48,0,0,0-2.18,1.14v-1h-2v7.57h2.05V12.75a1.42,1.42,0,0,1,1.41-1.57,1.34,1.34,0,0,1,1.4,1.52v4.42h2V12.35C53.32,10.68,52.46,9.35,50.58,9.35Z"/><path id="path20" class="cls-1" d="M58.2,15.47a1.94,1.94,0,0,1-1.94-2.14,1.92,1.92,0,0,1,1.91-2.12,1.64,1.64,0,0,1,1.67,1.27l1.83-.61a3.45,3.45,0,0,0-3.55-2.55,3.83,3.83,0,0,0-2.82,1.16,3.88,3.88,0,0,0-1.1,2.85,3.9,3.9,0,0,0,4,4,3.5,3.5,0,0,0,3.53-2.55l-1.8-.6A1.72,1.72,0,0,1,58.2,15.47Z"/><path id="path22" class="cls-1" d="M67,9.35a2.72,2.72,0,0,0-2.07.83V6h-2V17.12h2V12.67a1.43,1.43,0,0,1,1.42-1.48,1.34,1.34,0,0,1,1.4,1.53v4.41h2V12.35A2.67,2.67,0,0,0,67,9.35Z"/><path id="path24" class="cls-1" d="M75.82,11.05l-1.63-.35a1.58,1.58,0,0,1-1.4-1.59A1.93,1.93,0,0,1,74.9,7.3a2.21,2.21,0,0,1,2.3,1.86l1.36-.48a3.73,3.73,0,0,0-7.29.54,3,3,0,0,0,2.67,3l1.55.33c1.09.24,1.63.91,1.63,1.7,0,.95-.74,1.74-2.25,1.74a2.51,2.51,0,0,1-1.79-.63,2.45,2.45,0,0,1-.82-1.71l-1.45.46a3.79,3.79,0,0,0,4.08,3.24c2.32,0,3.76-1.52,3.76-3.22C78.65,12.59,77.63,11.45,75.82,11.05Z"/><path id="path26" class="cls-1" d="M83.25,16A2.33,2.33,0,0,1,81,13.41a2.31,2.31,0,0,1,2.24-2.59,1.93,1.93,0,0,1,2,1.57l1.31-.55a3.22,3.22,0,0,0-3.29-2.35,3.7,3.7,0,0,0-3.72,3.92,3.75,3.75,0,0,0,3.74,3.94A3.41,3.41,0,0,0,86.59,15l-1.28-.55A2,2,0,0,1,83.25,16Z"/><path id="path28" class="cls-1" d="M88.69,5.89a1,1,0,1,0,.75.29A1,1,0,0,0,88.69,5.89Z"/><polygon id="rect30" class="cls-1" points="87.99 9.72 89.42 9.72 89.42 17.11 87.99 17.11 87.99 9.72"/><path id="path32" class="cls-1" d="M14.58,8.87A4.1,4.1,0,0,0,15.8,6H14.31a2.62,2.62,0,0,1-.76,1.87L11.66,9.7l-2-2A2.61,2.61,0,0,1,9,6H7.53A4.09,4.09,0,0,0,8.74,8.87l1.87,1.87L8.74,12.61a4.08,4.08,0,0,0-1.21,2.92v2.29H9.18V16.73h1.66v1.09h1.64V16.73h1.65v1.09H15.8V15.53a4.11,4.11,0,0,0-1.21-2.92l-1.38-1.36-1,1.05,1.37,1.36a2.63,2.63,0,0,1,.77,1.58H9a2.68,2.68,0,0,1,.76-1.58Z"/><path id="path34" class="cls-1" d="M11.61,23.21a11.61,11.61,0,1,1,11.6-11.6A11.6,11.6,0,0,1,11.61,23.21Zm0-21.89A10.29,10.29,0,1,0,21.9,11.61,10.28,10.28,0,0,0,11.61,1.32Z"/></g></g></svg> </span> <span id="bechsci-tooltip-{{$ctrl.productId}}" class="bechsci-tooltip-icon" data-toggle="tooltip" ng-click="$ctrl.showBechSciTooltip()" close-tooltip="$ctrl.closeBechSciTooltip()" data-html="true" title="Clicking this link will redirect you to the <a href='https://www.benchsci.com/' target='_blank'> BenchSci</a> website that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented."> <?xml version="1.0" encoding="utf-8"?>  <svg version="1.1" id="Layer_1" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink" x="0px" y="0px" viewBox="0 0 16 16" style="enable-background:new 0 0 16 16;" xml:space="preserve"> <style type="text/css"> .st0{fill-rule:evenodd;clip-rule:evenodd;fill:#A2A2A2;} </style> <g id="Log-In-_x2F_-Out-States"> <g id="_x31_200-00-AB-PDP-Logged-Out-Card" transform="translate(-953.000000, -1013.000000)"> <g id="icons_x2F_16_x2F_info_x2F_bold" transform="translate(952.000000, 1012.000000)"> <path id="Shape" class="st0" d="M9,4c2.8,0,5,2.2,5,5s-2.2,5-5,5s-5-2.2-5-5S6.2,4,9,4 M9,2C5.1,2,2,5.1,2,9s3.1,7,7,7s7-3.1,7-7 c0-1.9-0.7-3.6-2.1-4.9S10.9,2,9,2z M8,8.5v4.4h2V8.5H8z M8,5.2v2h2v-2H8z"/> </g> </g> </g> </svg> </span> </div> </div> <div ng-cloak ng-if="$ctrl.currentElement.benchSciPubmedId && $ctrl.currentElement.benchSciPubmedId != '0'" class="pubmed-link"> <span ng-class="$ctrl.getSeperatorClass()">PMID: <a target="_blank" href="http://pubmed.ncbi.nlm.nih.gov/pubmed/{{ $ctrl.currentElement.benchSciPubmedId }}">{{$ctrl.currentElement.benchSciPubmedId}}</a> </span> </div> </div> <div class="btn-view-product" ng-cloak ng-show="false"> <a role="button" class="btn img-view-product"> View Product </a> </div> </div> </div> <div ng-show="$ctrl.isVideo" class="video-desc hide"> <h2 class="product-name" ng-bind="$ctrl.videoTitle"></h2> <p>{{$ctrl.videoDesc}}</p> <p>{{$ctrl.videoLongDesc}}</p> </div> </div> </div> <div class="nav-arrow" ng-if="!$ctrl.isMobileSmallTabletScreen()" onclick="window.THERMO_FISHER.inp.onClickOfRightArrow(event, this)"> <div tabindex="0" class="gallery-right-arrows icon-gallery-arrow-right"> </div> </div> </div> <image-gallery-key-nav pdp-gallery="true"></image-gallery-key-nav> <div class="film-strip"> <div id="custom-scrollbar" class="set-of-images"> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="90781" data-index="0"> <img src="https://www.thermofisher.com/antibody/images/150/15-0112-82_CD11b_Flow_1-20170119083539.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="1111088" data-index="1"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_29097_gr3.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="1017991" data-index="2"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_24742_biology-11-01609-g004.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="1018040" data-index="3"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_24742_biology-11-01609-g003.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="1139536" data-index="4"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_29101_gr8.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="1139534" data-index="5"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_29102_41467_2023_42182_Fig4_HTML.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="1139535" data-index="6"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_29102_41467_2023_42182_Fig6_HTML.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="1139533" data-index="7"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_29100_IJN-18-5495-g0006.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="1139532" data-index="8"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_29099_fimmu-14-1230681-g003.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="1139529" data-index="9"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_29098_fimmu-14-1147695-g001.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="1139531" data-index="10"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_29098_fimmu-14-1147695-g006.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="1139530" data-index="11"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_29098_fimmu-14-1147695-g002.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="1139528" data-index="12"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_29079_urn-x-wiley-0260437X-media-jat4496-jat4496-fig-0002.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="1019346" data-index="13"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_24743_fphar-13-1095757-g002.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="1019326" data-index="14"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_24741_12276_2022_851_Fig3_HTML.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="1019226" data-index="15"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_24737_urn-x-wiley-08941491-media-glia24255-glia24255-fig-0001.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="952239" data-index="16"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_20559_41467_2022_29730_Fig4_HTML.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="952219" data-index="17"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_20557_gr5.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="1019306" data-index="18"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_24740_41467_2022_29471_Fig9_HTML.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="1019286" data-index="19"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_24740_41467_2022_29471_Fig7_HTML.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="952198" data-index="20"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_20556_pntd.0010224.g002.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="1019266" data-index="21"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_19070_41467_2021_27683_Fig9_HTML.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="926410" data-index="22"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_19070_41467_2021_27683_Fig5_HTML.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="926374" data-index="23"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_19068_cells-10-03181-g003.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="926354" data-index="24"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_19067_fimmu-12-686769-g003.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="1019246" data-index="25"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_19067_fimmu-12-686769-g004.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="926273" data-index="26"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_14986_fphar-12-726586-g003.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="926173" data-index="27"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_14981_fimmu-12-701415-g001.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="926193" data-index="28"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_14981_fimmu-12-701415-g002.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="926213" data-index="29"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_14981_Image_1.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="926253" data-index="30"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_14984_aging-13-203340-g006.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="926334" data-index="31"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_14993_gr8.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="926314" data-index="32"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_14993_gr7.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="926293" data-index="33"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_14992_jrd-67-257-g006.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="926152" data-index="34"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_14980_40820_2020_540_Fig2_HTML.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="926233" data-index="35"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_14983_ADVS-8-2100787-g006.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="926132" data-index="36"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_14979_41467_2021_23832_Fig1_HTML.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="926112" data-index="37"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_14978_10020_2021_325_Fig4_HTML.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="926092" data-index="38"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_14990_pone.0252642.g005.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="926072" data-index="39"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_14977_41467_2021_23197_Fig5_HTML.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="926052" data-index="40"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_14977_41467_2021_23197_Fig4_HTML.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="926032" data-index="41"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_14977_41467_2021_23197_Fig3_HTML.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="926012" data-index="42"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_14976_PHY2-9-e14859-g005.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="925220" data-index="43"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_14952_urn-x-wiley-2051817X-media-phy214859-phy214859-fig-0001.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="841493" data-index="44"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_12627_jciinsight-6-143379-g148.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="1139527" data-index="45"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_29096_nihms-1689237-f0007.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="925972" data-index="46"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_14989_gr3.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="925952" data-index="47"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_14988_41467_2021_22053_Fig1_HTML.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="925992" data-index="48"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_14850_gr1.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="853803" data-index="49"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_9863_cells-10-00298-g001.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="853697" data-index="50"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_9861_gr4_lrg.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="853645" data-index="51"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_9861_gr3_lrg.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="925896" data-index="52"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_14987_nihms-1640051-f0007.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="925836" data-index="53"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_14987_nihms-1640051-f0004.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="925856" data-index="54"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_14987_nihms-1640051-f0005.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="925816" data-index="55"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_14987_nihms-1640051-f0003.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="925876" data-index="56"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_14987_nihms-1640051-f0006.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="925796" data-index="57"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_14987_nihms-1640051-f0001.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="925916" data-index="58"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_9936_biomedicines-08-00590-g001.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="925140" data-index="59"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_14947_urn-x-wiley-07415400-media-jlb10762-jlb10762-fig-0002.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="925200" data-index="60"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_14951_urn-x-wiley-00071188-media-bph15339-bph15339-fig-0005.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="925080" data-index="61"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_14944_urn-x-wiley-08941491-media-glia23948-glia23948-fig-0001.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="853410" data-index="62"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_9858_41467_2020_19833_Fig3_HTML.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="853583" data-index="63"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_9859_elife-60223-fig7.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="853449" data-index="64"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_9859_elife-60223-fig2.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="853533" data-index="65"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_9859_elife-60223-fig6.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="853489" data-index="66"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_9859_elife-60223-fig3.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="853351" data-index="67"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_9857_41419_2020_3223_Fig3_HTML.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="853281" data-index="68"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_9854_fimmu-11-574839-g001.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="925756" data-index="69"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_14973_13287_2020_2014_Fig1_HTML.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="853331" data-index="70"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_9856_cancers-12-03457-g003.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="853783" data-index="71"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_9862_aging-12-104176-g004.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="853763" data-index="72"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_9862_aging-12-104176-g003.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="853743" data-index="73"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_9862_aging-12-104176-g001.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="988232" data-index="74"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_19023_fimmu-11-536442-g002.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="925776" data-index="75"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_14974_jciinsight-5-135775-g143.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="853604" data-index="76"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_9860_nihms-1651551-f0006.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="853162" data-index="77"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_9851_fimmu-11-01856-g0002.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="839907" data-index="78"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_12509_41467_2020_18491_Fig2_HTML.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="853261" data-index="79"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_9853_41598_2020_72181_Fig1_HTML.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="852504" data-index="80"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_9832_41467_2020_18039_Fig1_HTML.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="851636" data-index="81"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_9817_jciinsight-5-136773-g165.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="853225" data-index="82"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_9852_cancers-12-02083-g004.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="853186" data-index="83"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_9852_cancers-12-02083-g002.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="925736" data-index="84"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_14971_cells-09-01634-g005.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="850623" data-index="85"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_8339_fimmu-11-00787-g005.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="853127" data-index="86"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_9849_41419_2020_2546_Fig4_HTML.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="925696" data-index="87"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_14970_cells-09-01106-g003.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="925716" data-index="88"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_14970_cells-09-01106-g006.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="841333" data-index="89"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_12622_41598_2020_64158_Fig3_HTML.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="841298" data-index="90"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_12621_BMRI2020-5417201.009.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="841270" data-index="91"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_12621_BMRI2020-5417201.008.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="841229" data-index="92"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_12621_BMRI2020-5417201.007.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="841009" data-index="93"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_12621_BMRI2020-5417201.002.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="840965" data-index="94"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_12621_BMRI2020-5417201.001.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="841185" data-index="95"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_12621_BMRI2020-5417201.006.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="841141" data-index="96"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_12621_BMRI2020-5417201.005.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="841053" data-index="97"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_12621_BMRI2020-5417201.003.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="841097" data-index="98"> <img src="https://www.thermofisher.com/antibody/images/150/tfs_12621_BMRI2020-5417201.004.jpg?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)"/> </div> </div> </div> </div> </div> <noscript> <div itemscope itemtype="http://schema.org/ImageGallery"> <h2>Product Image Gallery</h2> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/15-0112-82_CD11b_Flow_1-20170119083539.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Staining of mouse bone marrow cells with 0.06 µg of Rat IgG2b K Isotype Control PE-Cyanine5 (Product # 15-4031-82) (blue histogram) or 0.06 µg of Anti-Mouse CD11b PE-Cyanine5 (purple histogram).Cells in the large scatter population were used for analysis.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_29097_gr3.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Effects of ACSL4 deficiency on PQ-induced lung inflammation. (A) mRNA expression levels of inflammatory cytokines (IL-6 and IL-1beta), COX-2, GPx4, and chemokines (CXCL1, CXCL2, CXCL5, and CXCR2) in lung tissues of untreated or PQ-administered WT (blue columns) and ACSL4-KO mice (red columns); n = 4/group. * p < 0.05 and ** p < 0.01, untreated WT vs PQ-administered WT mice; # p < 0.05 and ## p < 0.01, PQ-administered WT vs ACSL4 KO mice. (B) Representative Gr-1 staining images of lung tissue of untreated or PQ-administered WT and ACSL4-KO mice. The scale bars represent 100 mum. (C) Flow cytometry analysis of CD11b + Ly6G/6C + neutrophils (upper) and CD11 + F4/80+ macrophages (lower) in the BAL fluid cells of untreated or PQ-administered WT and ACSL4-KO mice; cell samples were pooled from 5 mice per group. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.) Fig. 3</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_24742_biology-11-01609-g004.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Figure 4 TIM3-positive macrophages were recruited to ATC xenograft tumors. ( A ) I. Upper panel: TIM3 mRNA expression in RAW264.7 cells and in ATC xenografts. Total RNA was isolated, and the mRNA expression of TIM3 was examined by RT-PCR analysis. Lane 1, RAW264.7 cells; lanes 2-4, 8505C xenograft tumors ( n = 3); lanes 5-7, C643 xenograft tumors ( n = 3). The lower panel represents the expression of actin. II. TIM3 mRNA expression was normalized by beta-actin. Densitometry analysis of TIM3 is shown. Representative results of 3 independent experiments. ( B - D ) 20X and 63X images of 5 um thick 8505C xenograft tumor sections immunostained with TIM3-PE antibody (red). Nuclei were counterstained with DAPI. Representative immunofluorescence images of 3 independent experiments. ( E - G ) Representative FACS analysis of 2 independent experiments of macrophages (CD11b + F4/80 + TIM3 + ) out of all CD45 + cells in the 8505c xenograft tumors ( E ) and C643 xenograft tumors ( F ). ( G ) Quantification of the percentage of TIM3 + cells ( n = 6-8).</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_24742_biology-11-01609-g003.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Figure 3 M2-like macrophages were recruited to ATC xenograft tumors. ( A , B ) Representative FACS analysis of macrophages (CD11b + F4/80 + ) out of all CD45 + cells infiltrating 8505C xenograft tumors ( A ) and C643 xenograft tumors ( B ). ( C ) Quantification of the percentage of CD11b + F4/80 + cells ( n = 8-10). ( D , F ) Representative FACS analysis of M2-macrophages (CD11b + F4/80 + CD206 + ) out of all CD45 + cells infiltrating 8505C xenograft tumors ( D ) and C643 xenograft tumors ( E ). ( F ) Quantification of the percentage of CD11b + F4/80 + CD206 + cells ( n = 3-5). ( G , H ) Representative histograms of Arg1 ( G ) and iNOS ( H ) expression in CD206 low/int (blue histograms) and CD206 high (pink histograms) populations in total cells from C643 xenograft tumors. ( I ) Mean fluorescence intensity (MFI) of Arg1/iNOS ratio in the CD206 high group and in the CD206 low/int group ( n = 8-10). Data are expressed as mean +- SEM of 3 independent experiments. ** p < 0.005.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_29101_gr8.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Adrenergic signaling regulates CD11b expression in myeloid cells and controls migration into the liver after alphaGC treatment (A-E) C57BL/6J WT and Adra2ac -/- mice were treated with alphaGC (2mug/animal), and liver leukocytes were analyzed by flow cytometry after 3 h. Graphs represent the total number of liver leukocytes (CD45 +) (A), neutrophils (CD11b + Ly6G +) (B) and CD11b + F4/80 + cells (C), as well as the CD11b MFI in neutrophils (D) and CD11b + F4/80 + cells (E). (F-J) C57BL6/J WT animals were pre-treated with Yoh (5 mg/kg) or Phe (10 mg/kg) and then treated with alphaGC (2mug/animal). Liver leukocytes were analyzed by flow cytometry after 3 h, and graphs represent the total number of liver leukocytes (CD45 +) (F), neutrophils (CD11b + Ly6G +) (G) and CD11b + F4/80 + cells (H), as well as the CD11b MFI in neutrophils (I) and CD11b + F4/80 + cells (J). Data represent the mean +- SD from a single set of two independent experiments (n = 5). *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_29102_41467_2023_42182_Fig4_HTML.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Terminal maturation of NK cells is associated with the downregulation of Eomes. a - c Newborn C57BL/6 mice were intraperitoneally infected with 200 PFU of MCMV or mock-infected 24-36 h after birth. a On day 21 after infection, expression of Eomes and T-bet was determined by flow cytometry. b Eomes expression was analyzed on CD27 + CD11b - , CD27 - CD11b + , KLRG1 + and KLRG1 - NK cells from MCMV and mock-infected mice, representative histograms are shown. c Quantification of Eomes expressing CD27 + CD11b - , CD27 - CD11b + , KLRG1 + and KLRG1 - NK cells ( n = 9 mice per group, Mann-Whitney two-tailed test). Mean values +- SD are shown. d Newborn BALB/c and 129/SvJ mice were intraperitoneally infected with 200 PFU of MCMV or mock-infected 24-36 h after birth. On day 21 after infection, mice were euthanized and the frequency of terminally differentiated, KLRG1 and Eomes expressing splenic NK cells was determined ( n = 4 Mock BALB/C, n = 5 MCMV BALB/C, n = 6 Mock 129/SvJ, n = 3 MCMV 129/SvJ, Mann-Whitney two-tailed test). Mean values +- SD are shown. e Newborn C57BL/6 mice were intraperitoneally infected with 200 PFU of MCMV or mock-infected 24-36 h after birth. On days 60 and 90 after infection, mice were euthanized and the expression of KLRG1 and Eomes on NK cells was analyzed ( n = 3 Mock 60 d.p.i., n = 4 MCMV 60 d.p.i., n = 4 Mock 90 d.p.i., n = 6 MCMV 90 d.p.i., Mann-Whitney two-tailed test). Mean values +- SD are shown. f - h Adult C56BL/6 mice were infected with 2 x 10 5</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_29102_41467_2023_42182_Fig6_HTML.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Conventional NK cells downregulate Eomes upon perinatal MCMV infection. Newborn mice were intraperitoneally infected with 200 PFU of MCMV or mock-infected 24-36 h after birth. a, b On day 21 post-infection of C56BL/6 mice, spleens and livers were harvested. a Expression of CD49b and CD49a was analyzed on NK1.1 + cells, N = 2. b Expression of CD27, CD11b and KLRG1 by ILC1s (CD49b - CD49a + ) was determined by flow cytometry in the liver, N = 2. c On day 21 post-infection of Ncr1 iCre Eomes f/f (KO) or Eomes f/f mice (WT), CD27, CD11b and KLRG1 expression by splenic NK1.1 + cells were determined by flow cytometry. Numbers of terminally differentiated and KLRG1 expressing NK1.1 + cells are shown ( n = 8 WT, n = 6 KO, Mann-Whitney two-tailed test). Mean values +- SD are shown. d On day 21 post-infection of C56BL/6 mice, spleens and bone marrow were harvested. Representative histograms of Eomes expression by NK cells is shown ( N = 3). Statistically significant differences are indicated ( P values). Source data are provided as a Source Data file.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_29100_IJN-18-5495-g0006.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Intranasal delivery of EVs in the hydrogel inhibited inflammation. ( A ) Representative flow cytometry plots showing Ly6C high monocyte and Ly6C low monocytes/macrophages (CD45 + CD11b + ) in peripheral blood. and quantification of monocytes/macrophages (Ly6C high or low ) in peripheral blood. (n=5) ( B and C ). ( D ) Representative flow cytometry plots showing neutrophils (CD45 + CD11b + Ly6G + ) in peripheral blood and quantification of neutrophils in peripheral blood. n=5. ( E ). ( F ) Representative images of ventricles staining CD68 (green) showing the infiltration status of macrophages and quantification of CD68 + Cells. (n=5) ( G ). ELISA analysis of inflammatory factors IL-1 ( H ), IL-6 ( I ) and TNF-alpha ( J ) in peripheral blood. (n=5). (*P < 0.05, **P < 0.01, ***P < 0.001). Abbreviation : ns, not significant.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_29099_fimmu-14-1230681-g003.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Figure 3 P. anaerobius promoted oxaliplatin resistance by recruiting MDSCs into the CRC microenvironment. (A) Viability of MC-38 cells co-cultured with P. anaerobius or in conditioned medium supplemented with PA supernatant (CCK-8 assay, p > 0.05, PA indicated by red arrow). (B) MDSCs (Gr-1 + CD11B + ) from bone marrow of CRC mice detected by multicolor flow cytometry. (C, D) MDSCs infiltrated into the tumor microenvironment detected by fluorescein isothiocyanate (FITC) with anti-mouse CD11b antibody (green), allophycocyanin (APC), anti-mouse Gr-1 antibody (red), and DAPI (blue). (E) Morphological feature of MDSCs collected by FCM (Giemsa staining, purple-blue leaf-shaped or round-type nucleus and almost colorless cytoplasm). (F) Chemotaxis ability of MDSCs treated with PA -CM, MC-38-CM, and PA +MC-38-CM (co-culture medium of PA and MC-38), respectively. (A-F) Data were presented as mean +- SD, p- values were determined by one-way analysis of variance. Three independent experiments were performed with consistent results.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_29098_fimmu-14-1147695-g001.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Gastric G-MDSCs are characterized by a specific transcriptional signature and can be identified by calprotectin (S100a8 and/or S100a9) expression. (A) Representative FACS plots of gastric MDSC versus non-MDSC myeloid cell populations using CD11b and Ly6G cell-surface protein markers, of dissociated gastric cells from uninfected versus 6mo H felis -infected WT mouse stomachs. Red font ""1"" annotates gastric non-myeloid and Ly6G-negative cells. Green font ""2"" annotates CD11b + Ly6G - non-G-MDSC myeloid cells. Black font ""3"" annotates gastric CD11b + Ly6G + G-MDSC myeloid cells. Blue font ""4"" annotates gastric CD11b - Ly6G + non-myeloid cells. (B) Microarray heatmap showing the highest expressed genes that are specifically enriched in gastric CD11b + Ly6G - non-G-MDSC myeloid cells (annotated as green font ""2""), versus those specifically enriched in gastric CD11b + Ly6G + G-MDSC myeloid cells (annotated as black font ""3""), and those specifically enriched in non-myeloid gastric CD11b - Ly6G + control cells (annotated as blue font ""4""). The gene names for the calprotectin subunits S100a8 and S100a9, Il1b, Slfn4, and Cxcr2 are listed (S100a8 and Cxcr2 are annotated in red font because they will later be used in the study for Cre/Flox generation). (C) Representative image of the immunohistochemical staining of calprotectin (brown) in 6mo H felis -infected mouse gastric mucosa relative to uninfected.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_29098_fimmu-14-1147695-g006.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Cxcr2-deficient S100a8-expressing cells exhibit an altered expression of several genes associated with lipid metabolism, and an increase in the production of the lipid peroxidation product, 4-hydroxynonenal (4-HNE), within gastric epithelial lesions, following 6mo H felis infection. (A) Representative FACS plots of CD11b + Ly6G + G-MDSCs from H felis -infected S100a8 Cre/+ Cxcr2 flox/flox versus Cxcr2 flox/flox stomachs, which were used for sorting gastric G-MDSCs for microarray analyses. (B) Microarray heatmap of the MDSC-specific genes that exhibited altered expression patterns in G-MDSCs in response to Cre/Flox-mediated Cxcr2 ablation. Fabp5 is directly involved in lipid peroxidation and is annotated by a red arrow. (C) Immunohistochemical staining of 4-HNE staining (brown), within gastric epithelial lesions, in 6mo H felis -infected S100a8 Cre/+ Cxcr2 flox/flox versus Cxcr2 flox/flox stomachs. (D) Quantitative morphometry of 4-HNE staining. (E) Representative immunohistochemical staining of calprotectin (brown) in 6mo H felis -infected S100a8 Cre/+ Cxcr2 flox/flox versus Cxcr2 flox/flox stomachs. **P < 0.01.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_29098_fimmu-14-1147695-g002.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Figure 2 S100a8 and S100a9 are enriched in gastric G-MDSCs but not in acutely recruited gut neutrophils. (A) Representative FACS plots of gastric G-MDSCs versus cecal neutrophils in 6-month H felis -infected stomachs versus 2-day C difficile infected ceca respectively. (B) Microarray heatmap showing the highest expressed genes that are specifically enriched in gastric CD11b + Ly6G + G-MDSCs relative to CD11b + Ly6G + cecal neutrophils in 6-month H felis -infected stomachs versus 2-day C difficile infected ceca respectively. The black arrows annotate the genes that are highly expressed in G-MDSCs of 6 month H felis -infected stomachs but not in neutrophils of 2-day C difficile infected ceca.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_29079_urn-x-wiley-0260437X-media-jat4496-jat4496-fig-0002.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">2 FIGURE Flow cytometric analysis of peritoneal macrophages using CD11b-PerCPCy5.5, CD86-PE, and CD206-FITC antibodies after single or dual blocking of toll-like receptor 4 (TLR4) and tumor necrosis factor receptor 1 (TNFR1) and posttreatment with recombinant interleukin 10 (IL-10). Dot plot images of M1/M2 macrophage population analysis. Graphical representation of the CD86 + M1 population and graphical representation of the CD206 + M2 population in 11 different groups were shown. Data were represented as mean +- SD from three independent experiments. ""*"" indicates a significant difference in comparison with control in the non-IL-10-treated groups, ""#"" indicates a significant difference in comparison with lipopolysaccharide (LPS), ""*"" indicates a significant difference with respect to LPS + DEX, ""^"" indicates a significant difference with respect to TLR4Ab + LPS, ""EUR"" indicates significant difference with respect to TNFR1Ab + LPS, ""epsilon"" indicates significant difference with respect to control in the IL-10-treated group, ""delta"" indicates a significant difference in comparison with LPS + IL-10, ""$"" indicates significant difference with respect to LPS + DEX + IL-10, ""alpha"" indicates significant difference with respect to TLR4Ab + LPS + IL-10, and ""U"" indicates significant difference with respect to TNFR1Ab + LPS + IL-10. All the differences were statistically significant at p < 0.05 level.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_24743_fphar-13-1095757-g002.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">FIGURE 2 Alteration of cellular composition in the diseased status of mice and humans. (A,B) Fractions of major cells types in aneurysmal aorta vs. the corresponding normal aorta of humans (A) and mice (B) . (C) Immunofluorescence analysis for SMMHC (red), alphaSMA (green), and overlays with DAPI-labeled nuclei (blue) showing smooth muscle cells in the human vascular media (scale bars: 100 mum). Lu means the lumen side of the vascular wall, and A means the adventitia side of the vascular wall. (D,E) Immunofluorescence analysis for vimentin (white) (D) and CD45 (purple) (E) and overlays with DAPI-labeled nuclei (blue) showing fibroblasts and immune cells in the human aorta (scale bars: 100 mum). (F) Immunostaining for calponin (red), alphaSMA (green), and overlays with DAPI-labeled nuclei (blue) showing smooth muscle cells in the mouse aortic media (scale bars: 100 mum). (G) Immunostaining for vimentin (white) and DAPI overlay in the thoracic and abdominal aorta form mice subjected to 4 weeks of Ang II induction (scale bars: 500 mum). (H) Immunostaining for CD45 (red), CD68 (green), and overlays with DAPI-labeled nuclei (blue) showing macrophages in the mouse aorta (scale bars: 100 mum). (I) Flow cytometry of the proportion of macrophages (F4/80 + CD11B + ), monocytes (LY6C + CD11B + ), and T cells (CD3 + ) in CD45 + immune cells among three groups (n = 3-4, per group).</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_24741_12276_2022_851_Fig3_HTML.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Deletion of Cxxc5 ameliorates NASH progression. a - m Cxxc5 +/+ and Cxxc5 -/- mice were fed a HFD for 12 weeks and injected with CCl 4 twice a week for the final 4 weeks to induce NASH ( n = 7 per group). a Representative IHC images of F4/80- and Cd11b-stained liver tissues (left panel). Quantification of hCLS formation and F4/80- and Cd11b-positive areas (right panel). Scale bars, 100 um. b Flow cytometry analyses of the expression of F4/80 and Cd11b (left panel). Percentage of F4/80 + Cd11b + cells ( n = 3) (right panel). c Inflammation score. d Relative mRNA expression levels of genes involved in pro-inflammation ( n = 3). e The NAFLD score. f Representative images of DHE-stained cells (left panel). Quantification of ROS formation by measuring DHE-positive cells in liver tissues (right panel). Scale bar, 100 um. g TUNEL staining of the liver (top panel). Quantification of TUNEL-positive cells (bottom panel). Scale bar, 100 um. h Relative mRNA expression of genes involved in cell death pathways (n = 3). i Representative IHC images for alpha-Sma, collagen I, desmin, and Sirius red staining of liver tissues. Scale bars, 100 um. j Relative mRNA expression of genes involved in fibrogenesis ( n = 3). k The fibrosis score. l , m Plasma concentrations of FFAs ( l ), AST and ALT ( m ). Data represent the mean +- SD. * P < 0.05; ** P < 0.01; *** P < 0.001 determined by Student's t test.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_24737_urn-x-wiley-08941491-media-glia24255-glia24255-fig-0001.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">1 FIGURE Flow cytometry analysis of the CD11b+ cells. Cells isolated from non-perfused [(a)-(e)] and perfused [(f)-(j)] brains did not show significant differences. [(a), (f)] Histograms showing two CD45-expressing cell populations: CD45 low (microglia) and CD 45 high (possible macrophages). [(b), (g)] Microglia, identified as CD11b+ and CD45 low (Q3), comprised the highest proportion of cells (91.7%-94.5%), whereas a low percentage of potential macrophages (CD11b+/CD45 high, Q2) were observed. [(c), (h)] Forward scatter (FSC) analysis showing a slight smaller size of the CD45 low cells (red) respect to CD45 high (blue) cells. [(d), (i)] CD11b analysis showed a slight lower expression within CD45 low cells (red) respect to CD45 high (blue) cells. [(e), (j)] Forward scatter (FSC) and side scatter (SSC) characteristics of CD11b+/CD45 low (red) and CD11b+/CD45 high (blue) are shown</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_20559_41467_2022_29730_Fig4_HTML.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Fig. 4 CAF-1 depletion induces myeloid differentiation in vivo and a mixed-lineage transcriptional signature in HSPCs. a Schematic of polyI:C (polyinosinic:polycytidylic acid) inducible Mx1-Cre/LoxP system in mice. Flow cytometric analysis of BM MNCs is performed 72 hrs post-induction of mice bearing homozygous Chaf1b floxed alleles and Mx1-Cre ( Chaf1b fl /fl ; Mx1-Cre) and littermate controls ( Chaf1b +/+ ; Mx1-Cre). b Flow cytometric analysis of myeloid differentiation markers (CD11b and Gr1) showing overlaid density plots and histograms of wild-type (Chaf1b +/+ ) and Chaf1b-deleted (Chaf1b Delta/ Delta ) BM MNCs. c Quantification of gated populations in b showing mean and standard deviation of CD11b and Gr1 double-positive and double negative % populations from live BM MNCs isolated from n = 2 wild-type and n = 3 knockout littermates. d Schematic of Chaf1b depletion in primary HSPCs. HSPCs isolated from homozygous floxed mice ( Chaf1b fl /fl ) are transduced with retroviral vectors, either empty control (MIGR1-CTRL) or overexpressing Cre recombinase (MIGR1-Cre) and analyzed by RNA-seq 48 h following expansion in myeloid media conditions. e RNA-seq analysis showing percentages and numbers of upregulated or downregulated genes in CAF-1 OFF iGMPs, HOXA9 OFF iGMPs, and Chaf1b Delta/ Delta HSPCs. DEGs are filtered based on fold change >= 1.5 and FDR < 0.05. f Venn diagrams of unique and common DEGs between CAF-1 OFF iGMPs, HOXA9 OFF iGMPs, and Chaf1b Delta/ Delta HSPCs shown i</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_20557_gr5.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">The GOG stimulated BMSCs promoted the osteoclastogenesis of HSCs and the inhibited PERK pathway blocked the promotive effects of GOG on osteoblastic/osteoclastic differentiations. (a) The schematic diagram showed the designed induction procedure and scheduled detections at different timepoints. The HSCs were co-cultured with BMSCs in the transwell system for evaluation on the effects of GOG on osteoblastic and osteoclastic differentiations. The HSCs were cultured in the low chamber with 4 days of M-CSF (50 ng/mL) stimulus for inducing BMMs differentiation of HSCs. After 4 days M-CSF induction, the Flow cytometry analysis was conducted to evaluate the proportion of BMMs in total HSCs and the ALP staining was performed to evaluate the osteoblastic differentiation of BMSCs. The osteoclast differentiation medium containing 50 ng/mL M-CSF and 100 ng/mL RANKL was replaced at day 5 in the lower chamber for further analysis on osteoclastic differentiation of BMMs. In the subsequent induction of BMMs, the M1/M2 polarization was detected by M1/M2 specific markers (iNOS and arginase) immunofluorescent staining after 2 days of M-CSF + RANKL induction, and the calcium oscillation of BMMs was also detected after 2 days of M-CSF + RANKL induction. After 6 days of M-CSF + RANKL induction, the mature osteoclast differentiation from BMMs was verified by TRAP staining and the osteoblastic differentiation of BMSCs was evaluated by ARS staining. (b) The FACS analysis on the BMMs differentiation o</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_24740_41467_2022_29471_Fig9_HTML.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Pharmacological inhibitor of MLCK MW01-022AZ suppressed tumor inflammation and growth. a Schematic of LLC lung tumor implantation in C57Bl6 mice and MW01-022AZ treatment. b-d Effect of MW01-022AZ on LLC b gross tumor morphology ( n = tumors from 6 mice) c tumor volume ( n = 9 mice and d tumor weight at endpoint (21 days) ( n = 9 mice). *p < 0.0001 for vehicle vs MW01-022AZ treatment, determined by t -test. e FACS profiles and f quantification of Gr1-CD11b+ ( p = 0.1146) Gr1loCD11b+ (* p = 0.0402), Gr1hiCD11b+ (* p = 0.0146) myeloid cells in representative MW01-022AZ vs vehicle-treated tumors at endpoint (21 days) ( n = 3 mice), determined by t -test. For Facs gating scheme, see Supplementary Fig. 7b . g Quantification and h representative histographs of F4/80+ macrophages ( n = sections from 6 mice) *p < 0.0001 for vehicle or MW01-022AZ by t -test, CD31+ blood vessels ( n = sections from 7 mice) *p < 0.0001 for vehicle or MW01-022AZ by t -test, CD8+ T cells ( n = sections from 9 mice) *p = 0.0244 for vehicle vs MW01-022AZ by Mann-Whitney test in tissues from mice treated with vehicle or MW01-022AZ . i Model of integrin activation demonstrating that cytokine stimulation activates a pathway whereby PI3Kgamma induces MLCK210 and myosin activation and colocalization with Rap1, resulting in Rap1-mediated integrin alpha4 conformation changes and interaction of the integrin with the actin cytoskeleton. Data are presented as mean values +- SEM. Statistical significance determined by</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_24740_41467_2022_29471_Fig7_HTML.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Deletion of bone marrow cell MLCK210 inhibits tumor growth. a Schematic of bone marrow transplantation and tumor implantation. b Genomic PCR to detect Mlck 210 gene in peripheral blood cells from BMT transplanted mice ( n = 2 mice). c - e Tumor volumes ( c ), weights at endpoint (15 days) (*p < 0.0001 WT vs Mlck210 -/- BM) ( d ) and images of gross tumor morphology ( e ) from LLC tumors in WT mice transplanted with bone marrow from WT ( n = 10 mice) or Mlck210 -/- mice ( n = 10 mice). f Representative FACS profiles and g quantification of Gr1-CD11b+ ( p = 0.9724) Gr1loCD11b+ (*p = 0.0280), Gr1hiCD11b+ ( p = 0.8641) myeloid cells in representative WT vs Mlck210 -/- BM transplanted tumors harvested at endpoint (15 days) ( n = 3 mice). For Facs gating scheme, see Supplementary Fig. 7b . h Representative histographs and i quantification of F4/80+ macrophages/field ( n = sections from 5 WT mice and 5 Mlck210 -/- ) *p = 0.0009, CD31+ blood vessels/field ( n = sections from 5 WT and 3 Mlck210 -/- mice) *p = 0.001, CD8+ T cells/field ( n = sections from 5 WT and 4 Mlck210 -/- mice) *p = 0.019 in tumor sections and 100X H&E-stained tumor sections to detect percent necrosis/field ( n = sections from 5 mice) *p = 0.0004 from mice transplanted with WT vs Mlck210 -/- bone marrow. Data are presented as mean values +- SEM. Significance testing was performed by Student's t -test. Experiments were performed twice. Source data are provided with this article as a Source Data file.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_20556_pntd.0010224.g002.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">10.1371/journal.pntd.0010224.g002 Fig 2 During LdCen -/- ID infection, neutrophil derived increased CCL3 recruits significantly higher number of dendritic cells attributed with proinflammatory phenotype in the ear dLN compared to LdWT infection. (A) Parasitized neutrophils (Cd11b + Ly6G + Ly6c int RFP/mCherry + ) were flow sorted from the ear dLN 5d post infection and mRNA expression levels of CCL3 from sorted neutrophils in the ear dLN were estimated by qPCR as described in Materials and Methods and expressed as fold change from uninfected naive mice. The experiment was repeated three times with pooled digests from five to six ear dLNs per experiment. The data represent the mean values +- SD of results from three independent experiments that all yielded similar results (n = 5). ** p < 0.005 between the groups. (B) The gating strategy and individual flow plots for DCs (CD11b + Ly6G - Ly6C - CD11c + MHCII hi ) recruitment in ear dLNs 5d post infection is shown under CCL3 non-depleted or depleted condition. (C ) Total number of Cd11b + cells recruited in ear dLN 5 days post infection in mice depleted or not of CCL3 has been shown. (D) Changes in the total number of DCs per ear dLN. Values shown are the mean numbers of cells per ear dLN +- SD of results. 6-8 ear dLN, pooled data from 3 independent experiments that all yielded similar results (n = 6). *p< 0.05; ** p < 0.005, *** p < 0.0005 between the groups. ( E) Parasitized DCs (CD11b + CD11c + MHCII hi RFP/mCherry + ) were flo</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_19070_41467_2021_27683_Fig9_HTML.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Fig. 9 OPN induces lysosomal-dependent lipid metabolism in BMDMs. a Representative western blots (left) and quantification (right, n = 3 biologically independent samples) of OPN receptor alphav and beta3 expression in BMDMs and metabolically activated macrophages (MMes) after culture for 4 days in vitro. b Schematic diagram illustrating the co-culture system as indicated below ( c ). c , d Representative images ( c ) and quantification ( n = 5 biologically independent samples) ( d ) of crystal violet staining of BMDMs (ctrl) and MMes treated with or without rOPN for 24 h in a Transwell system. Scale bar: 50 mum. e Immunofluorescence images of buoyant BMDMs (F4/80) containing lipid vesicles (Perilipin 1) isolated from bone marrow supernatant at week 12. Scale bar: 15 mum. f FACS analysis of FC + (F4/80+ and CD11b+ , top) and Perilipin1+ (bottom) BMDMs from NFD- (left) and HFD-fed (right) mice. P9, FC + and Perilipin1+ BMDM population from Q2. g Percentage of FC + and Perilipin1+ BMDMs ( n = 5 biologically independent samples). h Lactate concentration in bone marrow supernatant ( n = 5 biologically independent samples). i Schematic diagram illustrating the co-culture system as described below ( j ). j Immunofluorescence staining of the co-cultured BMDMs for 4 days in vitro; the eWAT from mice fed the HFD for 8 weeks was placed in the upper chamber; Neu Ab (2.0 mug/ml) was added into the lower chamber. Scale bar: 50 mum. The right-most image is an enlarged view of the field in t</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_19070_41467_2021_27683_Fig5_HTML.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Fig. 5 OPN is primarily secreted by F4/80 + and CD11b+ macrophages in eWAT. a Representative images of immunofluorescence staining of OPN in eWAT from NFD- and HFD-fed mice at weeks 8, 12, and 16. Scale bar: 100 mum. b Quantification of the F4/80-positive or OPN-positive stained area percentage in eWAT from a ( n = 4 biologically independent samples). c Relative expression of Spp1 in the adipocyte fraction (AF) and stromal vascular fraction (SVF) from eWAT or iWAT of HFD-fed mice at week 12 ( n = 3 biologically independent samples). d ATMs gated by FACS for F4/80 and CD11b expression from eWAT at week 12 of NFD (left) or HFD feeding (right). Q2 represents the F4/80 + CD11b + (FC + ) ATM population, and Q3 represents the F4/80-CD11b- (FC-) ATM population. e Percentage of FC + ATMs from NFD- and HFD-fed mice at week 12 ( n = 4 biologically independent samples). f Relative expression of Spp1 in FC+ and FC- ATMs from HFD-fed mice at week 12 ( n = 3 biologically independent samples). Images are representative of 3 independent experiments. All data are presented as mean +- SD. Two-way ANOVA with Sidak's post-hoc test ( b ) and two-tailed Welch's t -test ( c , e , f ) were used. Source data are provided as a Source Data file.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_19068_cells-10-03181-g003.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Figure 3 Flavivirus infection resulted in peripheral immune cell infiltration and inflammatory activation in the brain. In DENV-, JEV-, and ZIKV-infected hippocampi, hematoxylin & eosin staining (H&E) showed cell infiltration ( A ). ( B ) Immunofluorescent staining of Iba1 (green) indicated macrophage expression. DAPI (blue) was stained for nuclei. ( C ) The gating strategy in specific regions (R1-3) used to identify resident macrophages or microglia (RM, CD45 low CD11b + ) and infiltrated macrophages (IM, CD45 high CD11b + ). ( D ) The quantitative number of RMs and IMs in DENV-, JEV-, and ZIKV-infected brains ( n = 3). ( E ) Immunoprofile of macrophage polarization toward type 1 (CD80 and CD86) or type 2 (CD163 and CD206) in the RM and IM of infected mice ( n = 3). * p < 0.05, ** p < 0.01, and *** p < 0.001; ns, not significant. ( F ) Gene ontology enrichment analysis showed the changed gene count involving the inflammatory activation pathway. ( G ) Venn diagrams showed the commonality of inflammatory gene expression in three flavivirus infections. Scale bar = 400 mum.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_19067_fimmu-12-686769-g003.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Figure 3 ADRbeta3+ cells express several macrophage markers, but lack expression of CD11b and F4/80. Macrophage surface markers were quantified on ADRbeta3+ macrophages, bone-marrow-derived macrophages(BMDM), and microglia. Comparisons were made between these cell types to determine commonality. Significant differences (p<0.5) were calculated using an ANOVA with Tukey correction. Symbols represent sample data points, and horizontal lines depict the mean. Standard error of the mean (SEM) is shown by the capped vertical line. *p < 0.05, ***p < 0.001. Flow cytometry was used to quantitate all types of macrophages in both the Figure 3 legend as well as in the test in the Results. Adrb3+ macrophages, BMDM, and microglia were compared for percent positivity to (A) Adrb3; (B) Csf1r; (C) Mrc1; (D) Cd45; (E) Cd68; (F) Cd11b; (G) F4/80; (H) Ccr2; and (I) , Tmem119.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_19067_fimmu-12-686769-g004.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">ADRbeta3+ macrophages show sensitivity to clodronate liposomes. (A) Quantitation of ADRbeta3+ cells or (B) Cd11b+ macrophages by flow cytometry in tissues isolated 4 days after induction of HO in mice in the presence of clodronate or saline liposomes. (C) Analysis of bone volume in tissues isolated 2 weeks after induction of HO in mice in the presence of clodronate or saline liposomes using microCT. Significant differences (p<0.5) were calculated using an ANOVA with Tukey correction. Symbols represent sample data points, and horizontal lines depict the mean. Standard error of the mean (SEM) is shown by the capped vertical line. *p < 0.05, **p < 0.01. (D) Individual slices of both saline- and clodronate-treated samples were compared. Also shown for comparison is the mineral density of heterotopic bone.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_14986_fphar-12-726586-g003.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">FIGURE 3 E-cigarette increases macrophage numbers in lungs. (A,C) FACS analysis of cell population of CD45 + F4/80 + macrophages and CD11b + Ly6G + neutrophils in lung tissues of betaENaC mice with or without ENDS exposure ( n = 3 per group). (B,D) Quantification of FCAS analysis of macrophage and neutrophil population as in (A) and (C) , respectively. All data presented at mean +- SEM.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_14981_fimmu-12-701415-g001.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Figure 1 Desiccation stress recruits monocytes into the conjunctiva in a CCR2 dependent manner. The gating strategy used for these experiments is provided in Supplementary Figure 1A . (A) Single cell suspensions prepared from conjunctivae of C57BL/6 (B6) and Ccr2 -/- strains were stained with anti-CD45, CD11b, MHCII, CD64, Ly6c and MerTK. Squares within the representative plots show frequency of CD45 + CD11b + MHCII - CD64 + Ly6C high (classical monocytes) and CD45 + CD11b + MerTK + (tissue resident macrophages) cells (n = 6/group); (B) Experimental design, bone marrow cells from Pepc/BoyJ (2x10^6) were adoptively transfer via intra-orbital injection at 2 day time intervals and the recipient mice either remained in normal environmental conditions (NS) or were exposed to desiccating stress for 5 days (DS5) (n = 6/group); (C) relative fold change in CCL2 mRNA after desiccating stress for 1 day (DS1) (n = 6/group); (D) Adoptively transferred cells were tracked by gating on CD45.1 + , squares within the representative plots showing frequency of classical monocytes (top) and CD45 + CD11b + MHCII + cells (bottom). The bar graphs on the right side indicate the percentages of these cells with each dot representing one animal (n = 6/group); (E) Ccr2 -/- /Ccr2 +/+ bone marrow chimera. Bone marrow ablation in Pepc/BoyJ mice was accomplished with 137 Cs irradiation with 1300 cGy, followed by intraorbitally injection of 2x10^6 bone marrow cells from Ccr2 -/- /CD45.2 (2x10^6) or wild type</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_14981_fimmu-12-701415-g002.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Figure 2 Immune cells phenotype in the conjunctiva of B6 mice following desiccation stress. The gating strategy used for these experiments is provided in Supplementary Figure 1A . (A) Single cell suspensions prepared from conjunctivae of C57BL/6 (B6) mice housed in normal humidity (NS) or exposed to desiccating stress for 3 (DS3) or 5 (DS5) days were stained with anti-CD45, CD11b, MHCII, CD64, Ly6c and CD11c. A dump channel (anti-NK1.1/Ly6G/CD3e/CD45R/B220) was included to remove NK cell, granulocyte, T cell and B cells lineages. The four quadrants of the representative plots show percentages of the selected population. (B) Flow cytometry data from each group are visually presented in the bar graphs (n=6, dots are individual samples). The non-stressed (NS) group was statistically compared with the DS3 or DS5 groups using the Student T-test; (C) Representative flow plots of Ly6C and MHCII in the NS, DS3 and DS5 groups (left) with histograms of mean fluorescence intensities (MFI) (right); (D) MFI of CD64 + cells among MHCII - Ly6c high and MHCII + Ly6c low population. *p < 0.01, **p < 0.001, ***p < 0.0001.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_14981_Image_1.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_14984_aging-13-203340-g006.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Figure 6 Myeloid DJ-1 deficiency attenuates APAP induced hepatic inflammatory reaction via less ROS production and chemokines induction. Fasted DJ-1 fl/fl and Lysm-DJ-1 -/- mice were intraperitoneal injected with a single dose of 300 mg/kg of APAP. Quantification of Ly6G + CD11b + neutrophils ( A ) and Ly6C + CD11b + macrophages ( B ) by flow cytometry ( n = 4). ( C ) Quantification of CXCL1 and CXCL2 expression in liver tissue 24 h after APAP challenge ( n = 5-8). ( D ) Quantification of cellular ROS levels by oxidized DCFDA and flow cytometry in neutrophils and macrophages isolated from DJ-1 fl/fl and Lysm-DJ-1 -/- mice ( n = 4). Data are shown as the means +- SD, * P < 0.05; ** P < 0.01; *** P < 0.001; **** P < 0.0001.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_14993_gr8.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Figure 8 Combination of chemotherapy and immune activation within intratumoral TLSs is necessary for antitumor activity. ( A ) Schema of short-term administration of gemcitabine in combination or not with intratumoral injection of lymphoid chemokines CXCL13 and CCL21 in orthotopic mice. ( B ) TLS density after coinjection of gemcitabine and chemokine (C+G) compared with appropriate controls (PBS [S], chemokine [C], or gemcitabine [G] alone. ( C ) Flow cytometric analysis of CD45 + immune cells in PBS-treated (S) (n = 7) gemcitabine-treated (G) (n = 9) mice, chemokine-treated (C) (n = 6), and C+G-treated (n = 8) mice. Flow cytometric analysis of lymphoid and myeloid immune cells per gram of tumor tissue after chemokine and/or chemotherapy injection. ( D ) B cells (CD19 + ), ( E ) CD3 + T cells, ( F ) CD8 + T cells, ( G ) CD4 + T cells, ( H ) dendritic cells (CD11c + ), ( I ) myeloid cells (CD11b + ), ( J ) MDSC Ly6GC + subset, ( K ) macrophages (F4/80 + , MHC-II + ). ( L ) Tumor volume in C+G-coinjected mice and appropriate controls (chemokines [C], or gemcitabine [G] alone). Each data point represents 1 mouse (S n = 7, C n = 6, G n = 9, C+G n = 9). Kolmogorov-Smirnov test. * P < .05, ** P < .01, *** P < .001.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_14993_gr7.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Figure 7 Differential immune cell infiltration after chemokine injection in orthotopic murine tumors. Flow cytometric analysis, in lymphoid aggregate negative tumors from PBS-treated (n = 6) and TLS + CXCL13/CCL21-treated (n = 6) mice, of ( A ) CD19 + B cells out of CD45 + cells, ( B ) CD3 + T cells out of CD45 + cells, ( C ) CD8 + cytotoxic T cells out of CD3 + T cells, ( D ) CD4 + helper T cells out of CD3 + T cells, ( E ) FOXP3 + regulatory T cells out of CD4+CD3 + T cells, ( F ) CD11b + myeloid cells out of CD45 + cells, and ( G ) tumor weight in LA - tumors from PBS-treated (n = 6) and TLS + CXCL13/CCL21-treated (n = 6) mice. Each data point represents 1 mouse. Two-sample Kolmogorov-Smirnov test: * P < .05 and ** P < .01. ns, not significant.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_14992_jrd-67-257-g006.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Fig. 6. Effects of maternal aging on immune cell populations in the placenta and spleen. The placenta and spleen were collected from young, middle, and aged pregnant mice. Percentages of immune cells (CD45 + cells), neutrophils (CD45 + /Ly6G + cells or CD45 + /CD11b + cells), macrophages (CD45 + /F4/80 cells) in the placenta and spleen were analyzed by flow cytometry (A-H). Significant differences were detected using nonparametric analysis of variance; * P < 0.05.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_14980_40820_2020_540_Fig2_HTML.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Fig. 2 a Schematic diagram of biomaterial-mediated macrophage polarization and MSC osteogenesis. b FACS of all macrophages (F4/80 + , CD11b +), M2 macrophages (F4/80 + , CD11b + , CD206 high , MHC II low ) and M1 macrophages (F4/80 + , CD11b + , CD206 low , MHC II high ) recruitment at 2 weeks after biomaterials implantation in vivo. c Semiquantification of gating strategy cells in (B). n = 6, **** P < 0.0001, ns: not significant. d IHC staining of F4/80--macrophage marker, Arg1--M2 macrophage marker and iNOS--M1 macrophage marker at 4 weeks after biomaterials implantation in vivo. Red arrow, positive cell. Scale bar = 100 mum. M, material. e Semiquantification of positively stained cells in ( d ). n = 5, *** P < 0.001, **** P < 0.0001, ns: not significant. f Immunofluorescent (IF) staining of Arg1 (red), iNOS (green) and nuclei (blue) after macrophages seeded on the BCP or beta -TCP for 24 h. Scale bar = 5 mum. g Semiquantification of positively stained cells in ( f ). n = 5, **** P < 0.0001. h Relative mRNA expressions of macrophage polarization-related genes. M2 macrophage polarization-related anti-inflammatory genes (Arg1, IL-10) and the M1 macrophage-related pro-inflammatory gene (TNF-alpha, iNOS). n = 3, ** P < 0.01, *** P < 0.001, **** P < 0.0001. i, j ARS staining of MSCs on day 21 and semiquantification of mineralized nodules. n = 3, ** P < 0.01, *** P < 0.001, **** P < 0.0001</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_14983_ADVS-8-2100787-g006.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Figure 5 Biodistribution and targeting specificity of PLM-miRs in vivo. A) Circulation profiles of miRs, MSN-miRs, LM-miRs, and PLM-miRs in healthy mice after intravenous injection ( n = 6). B) RFI of heart tissue homogenate after treated with DiD (on liposome) labeled LM-miRs or PLM-miRs at 24 or 48 h post injury ( n = 6). C) IVIS images of three timepoints (1, 3, 24 h) of LM-miRs or PLM-miRs accumulated in the hearts after i.v. injected in MI/R mice and D) were further quantified the data of the first time point ( n = 6). E) Flow cytometry analysis of the binding ability of PLM-miRs to Ly6C+ monocytes in the blood circulation after intravenous injection at 72 h post-MI and G) was further quantified ( n = 6). F) Flow cytometry and statistical analysis of H) CD11b+, I) CD11b+DiD+, and J) CD11b+DiD- cells isolated from MI/R induced murine hearts after exposure to either LM-miRs or PLM-miRs injected at 24 or 72 h post-MI ( n = 6). K) CLSM images of heart sections showing the accumulation of LM-miRs and PLM-miRs after immuno-stained with cardiac troponin T (cTnT). Red, DiD (on liposome) labeled nanoparticles; Green, TnT. Scalar bar, 50 um. L) CLSM images of heart sections showing the colocalization between monocytes/macrophages and LM-miRs or PLM-miRs after immuno-stained with CD11b. Red, DiD (on liposome) labeled nanoparticles; Green, CD11b. Scalar bar, 20 um. Results are presented as mean +- SD. NS P > 0.05, * P < 0.05, ** P < 0.01, *** P < 0.001.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_14979_41467_2021_23832_Fig1_HTML.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Fig. 1 Genetic ablation of IL-6 reverses GBM immunosuppression. GBM was induced by RCAS-mediated genetic engineering in Ntv-a ; Ink4a-Arf -/- ; Pten fl/fl ; LSL-Luc donor mice, followed by orthotopic tumor implantation into Cdh5-Cre ERT2 ; Il6 fl/fl recipient mice that were pretreated with (IL-6-DeltaEC) or without (Control) tamoxifen. Two weeks after tumor implantation, tumors were excised. a Schematic approach. b , c Tumor-derived single-cell suspensions were analyzed by CyTOF. b Representative CyTOF sorting. c Quantitative results (mean +- SEM, n = 4 mice). Statistical analysis by two-tailed Student's t -test. d - f Tumor-derived single-cell suspensions were analyzed by flow cytometry. d Analysis for CD3 + T cells. Left, representative cell sortings. Right, quantified results ( n = 6 mice, mean +- SEM). Statistical analysis by two-tailed Student's t -test. e , f Analysis for e CD4 + /CD8 + T cells or f myeloid cells ( n = 6 mice, mean +- SEM). Statistical analysis by two-tailed Student's t -test. g , h Tissue lysates from normal brains and tumors were subjected to ELISA analysis for g IL-10 and h TGF-beta expression (mean +- SEM, n = 4 mice for IL-6-DeltaEC GBM group and n = 3 mice for other groups). Statistical analysis by two-way ANOVA with Sidak's test. Source data are provided as a Source data file.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_14978_10020_2021_325_Fig4_HTML.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Fig.4 Infiltrating monocytes and neutrophils were deceased in CD36 -/- mice. LMNCs were purified from APAP treated mice and stained with CD11b, Ly6C and Ly6G antibodies. Infiltrating monocytes (CD11b + Ly6C + ) and neutrophils (CD11b + Ly6G + ) were analyzed by FACS. *P < 0.05. N = 6 mice per group</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_14990_pone.0252642.g005.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">10.1371/journal.pone.0252642.g005 Fig 5 Innate immune responses at PN25 compared with PN12 in Wt offspring from dams exposed to LPS at a dose of 90 ug/kg (LPS90) late in gestation. LPS administered i.p. to pregnant Wt dams at E15.5. Expression of splenic innate immune cells and intracellular HO-1 in Wt offspring were determined at PN25 by flow cytometry (Wt LPS90 PN12, n = 4; Wt LPS90 PN25, n = 4). CD45 + common leukocyte antigen. CD11b + Ly6G + neutrophils. CD11b + CD11c + DCs. CD11b + Ly6C + (mononuclear cells). Intracellular HO-1 expression in neutrophils, DCs, and monocytes. Cell populations are shown as percentages of CD45 + cells and intracellular HO-1 expression as median fluorescent intensities (MFIs). Values are expressed as mean +- SD, p < 0.05, Student's t-test with Welch correction.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_14977_41467_2021_23197_Fig5_HTML.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Fig. 5 Gata6 deletion in cavity macrophages did not affect injury repair in the liver. a Schematic figure showing the experimental design. b Flow cytometric and quantification analysis of the percentage CD11b + F4/80 + macrophages expressing tdTomato from the pleural and peritoneal cavity. Data are the mean +- SD; n = 5 mice per group; **** P < 0.0001. c Schemati c figure showing the experimental design. d Immunostaining for tdTomato and F4/80 on dissociated cells from peritoneal cavity at 9 weeks and 13 weeks after TAM. Data are the mean +- SD; n = 5 mice per group. **** P < 0.0001. Each image is representative of five individual biological samples. e , f Flow cytometric analysis and quantification of the percentage of CD11b + F4/80 + macrophages expressing tdTomato. Data are the mean +- SD; n = 5 mice per group; **** P < 0.0001. g Schematic figure showing the experimental design. HI heat injury. h Whole-mount bright-field and fluorescence images of livers collected at 7 days after heart injury. Boxed regions are magnified; circles, heat injury site. Each image is representative of eight individual biological samples. i Quantification of injury size at 4 h and 7 days post HI. Data are the mean +- SD; n = 8 mice per group; ns nonsignificant. j Schematic figure showing the experimental design. k Whole-mount bright-field and fluorescence images of livers collected at 5 days after injury. Each image is representative of five individual biological samples. l Quantification of bod</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_14977_41467_2021_23197_Fig4_HTML.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Fig. 4 Genetic ablation of cavity macrophages did not affect liver repair after injury. a Schematic figure showing the experimental design. DT diphtheria toxin. b Flow cytometric and quantification analysis of the percentage of CD11b + F4/80 + macrophages expressing tdTomato from peritoneal cavity after PBS treatment (no DT). Data are the mean +- SD; n = 5 mice per group; ns nonsignificant. c Immunostaining for tdTomato and F4/80 on dissociated cells from the peritoneal or pleural cavity after DT treatment of the G6Mo-CreER;R26-tdTomato/iDTR mice. Quantification of the percentage of F4/80 + macrophages expressing tdTomato. Data are the mean +- SD; n = 5 mice per group; **** P < 0.0001. Each image is representative of five individual biological samples. d Flow cytometric and quantification analysis of the percentage of CD11b + F4/80 + macrophages expressing tdTomato in the pleural cavity, and peritoneal cavity, respectively. Data are the mean +- SD; n = 5 mice per group; **** P < 0.0001. e Schematic figure showing the experimental design. HI heat injury. f Whole-mount bright-field and fluorescence images of livers at 7 days after HI. Boxed regions are magnified; circles, heat injury site. Each image is representative of eight individual biological samples. g Quantification of injury size from 4 h to 7 days after heart injury. Data are the mean +- SD; n = 8 mice per group; ns nonsignificant. h Schematic figure showing the experimental design. i Whole-mount bright-field and fluo</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_14977_41467_2021_23197_Fig3_HTML.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Fig. 3 Pleural macrophages do not invade deep into the lung parenchyma after bleomycin treatment or CI. a Schematic figure showing experimental strategies. CI cryoinjury. b Whole-mount bright-field and fluorescent images of lungs after different injuries. Dotted line, CI region. Scale bars, 1 mm. c Sirius red staining of lung tissue sections after bleomycin or cryoinjury in lungs. Boxed regions are magnified. Scale bars, 100 um. d Immunostaining for tdTomato, GATA6, and F4/80 on injured regions of lungs. m.l., mesothelial layer. Boxed regions are magnified. Scale bars, 100 um. e , f FACS and quantification analysis of the percentage of macrophages expressing tdTomato from injury regions of the lung. Data are the mean +- SD; n = 5 mice per group. Each image is representative of five individual biological samples ( b - d ). Source data are provided as a Source Data file.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_14976_PHY2-9-e14859-g005.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">FIGURE 1 Long-term exercise restores the foreign-body phagocytic capacity of Kupffer cells (KCs) in p62 -KO mice. (a) Blood lactate concentration pre- and post-exercise. The body mass of wild-type mice fed a standard diet (WT, n = 3), resting p62 -KO mice fed a standard diet ( p62 -KO-Rest, n = 8), and p62 -KO fed a standard diet that exercised for 4 weeks ( p62 -KO-Ex, n = 8). (b) Latex bead-phagocytic capacity of F4/80 positive cells (KCs) and their mean fluorescence intensity (MFI) in the livers of mice in each group. The MFI of the latex beads was determined using flow cytometry ( n = 3/group). (c and d) Expression of the surface markers CD68 and toll-like receptor (TLR) 4 (C), and CD11b (M1) and CD206 (M2) (d) in KCs from the livers of mice in each group ( n = 3-4/group). (e) Lipopolysaccharide (LPS) concentrations in the peripheral and portal circulations and the differences between these ( n = 5-6/group). (f) Dehydroepiandrosterone (DHEA) concentration in the peripheral blood ( n = 6-8/group). Values are mean +- SE. * p < 0.05, compared with the WT group. + p < 0.05, compared with the p62 -KO-Rest group</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_14952_urn-x-wiley-2051817X-media-phy214859-phy214859-fig-0001.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">1 FIGURE Long-term exercise restores the foreign-body phagocytic capacity of Kupffer cells (KCs) in p62 -KO mice. (a) Blood lactate concentration pre- and post-exercise. The body mass of wild-type mice fed a standard diet (WT, n = 3), resting p62 -KO mice fed a standard diet ( p62 -KO-Rest, n = 8), and p62 -KO fed a standard diet that exercised for 4 weeks ( p62 -KO-Ex, n = 8). (b) Latex bead-phagocytic capacity of F4/80 positive cells (KCs) and their mean fluorescence intensity (MFI) in the livers of mice in each group. The MFI of the latex beads was determined using flow cytometry ( n = 3/group). (c and d) Expression of the surface markers CD68 and toll-like receptor (TLR) 4 (C), and CD11b (M1) and CD206 (M2) (d) in KCs from the livers of mice in each group ( n = 3-4/group). (e) Lipopolysaccharide (LPS) concentrations in the peripheral and portal circulations and the differences between these ( n = 5-6/group). (f) Dehydroepiandrosterone (DHEA) concentration in the peripheral blood ( n = 6-8/group). Values are mean +- SE. * p < 0.05, compared with the WT group. + p < 0.05, compared with the p62 -KO-Rest group</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_12627_jciinsight-6-143379-g148.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Figure 3 Brd4 -CKO mice had reduced expression of Gdf3 in ATMs. ( A ) PCA of RNA-Seq data derived from CD11b + ATMs of WT and Brd4 -CKO mice fed a HFD for 20 weeks. ( B ) Volcano plot of mRNA-Seq analysis in ATMs as indicated in A . Brown dots represent genes increased in ATMs of Brd4 -CKO mice vs. WT mice (fold change >= 2, adjusted P value <= 0.001, calculated by raw count value). Blue dots represent genes decreased in ATMs of Brd4 -CKO mice vs. WT mice (fold change >= 2, adjusted P value <= 0.001, calculated by raw count value). Gray dots represent genes without significantly altered expression. Clusters of significantly altered genes (fold change >= 2, adjusted P value <= 0.001, calculated by raw count value) were identified using gene ontology terms ( C ) and KEGG pathways ( D ). ( E ) Heat map of the relative expression levels (scaled Z -score) of cytokine-cytokine receptor interaction-related genes clustered in ( D ). ( F ) mRNA levels of Gdf3 in CD11b + ATMs isolated from WT or Brd4 -CKO mice fed a HFD for 20 weeks. ( G ) Left panel: Gdf3 or F4/80 IHC staining of eWAT of WT or Brd4-CKO mice fed a HFD for 20 weeks. Right panel: statistical analysis of Gdf3-positive or F4/80-positive area percentage, the ratio of Gdf3-positive cells in F4/80-positive cells in eWAT of WT and Brd4 -CKO mice fed a HFD. Data are mean and SD and are determined by an unpaired 2-tailed Student''s t test. n = 3 mice. ** P < 0.01. Brd4 -CKO, myeloid lineage-specific Brd4 knockout; HFD, high-fat</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_29096_nihms-1689237-f0007.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Figure 6. Decreasing monocyte-derived macrophages enhances CD8 T cell and neutrophil infiltration (A) Ptch1 +/- Tp53 -/- (Ccr2WT) and Ccr2 -/- mice were bred to produce Ptch1 +/- Tp53 -/- Ccr2 -/- (Ccr2KO) mice. (B) Flow cytometry of cerebellar myeloid cells showing reduced Cd11b + Cd45 hi Ly6G - Ly6c hi cells in irradiated Ccr2KO mice. Student's t test. N = 8 Ccr2WT mice, 6 Ccr2KO mice. Results are expressed as mean +- SEM. *p <= 0.05. (C) UMAP plots of scRNA-seq of cerebellar leukocytes from irradiated Ccr2WT and Ccr2KO showing reduced monocyte-derived macrophages and enhancedneutrophils in the latter. (D) RNAscope in situ with Siglech (black) and Clec12 (red) probes showing reduced accumulation of Clec12a -positive cells in irradiated Ccr2KO in comparison to Ccr2WT of Figure 5C . Scale bar: 50 muM. (E and F) Immunohistochemical staining with Ly6G (E) and CD8 (F) antibody showing an increase in neutrophil and CD8+ T cells in irradiated tumors from Ccr2KO (right plots) compared with Ccr2WT (left plots). Student's t test. n = 3 animals per treatment group. Results are expressed as mean +- SEM. **p <= 0.01, ***p <= 0.001. Field: 3,190 x 1,974 mum. Scale bar: 200 muM. See also Figure S6 .</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_14989_gr3.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Figure 3 Isolation of TDE-treated DC ex vivo (A) Uptake of PKH67 labeled exosomes by BMDC. (B) Injection of PKH67 labeled exosomes into the mice footpad. (C) Location of popliteal lymph nodes and inguinal lymph nodes of mice. (D) Flow cytometry and gating strategy of PKH67-uptaken DCs.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_14988_41467_2021_22053_Fig1_HTML.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Fig. 1 ASXL1-MT causes dysfunction of HSPCs associated with increased apoptosis and altered cell cycle status. a Enumeration of white blood cells (WBC), hemoglobin (Hb), and platelets (Plt) in peripheral blood of young Vav-Cre ASXL1-MT KI mice ( n = 13 (Control), 11 (ASXL1-MT)). b Frequency of myeloid cells (CD11b + ), B cells (B220 + ), and T cells (CD3 + ) in peripheral white blood cells of young Vav-Cre ASXL1-MT KI mice ( n = 13 (Control), 11 (ASXL1-MT)). c Absolute numbers of bone marrow cells per leg in young Vav-Cre ASXL1-MT KI mice ( n = 5). d Frequency of LSK cells, multipotent progenitors (MPPs), short-term HSCs (ST-HSCs) and long-term HSCs (LT-HSCs) in bone marrow cells of young Vav-Cre ASXL1-MT KI mice ( n = 5). e The experimental design for competitive transplantation assays. 3000 MPPs or 200 LT-HSCs isolated from young control or young Vav-Cre ASXL1-MT KI mice were transplanted into lethally irradiated recipient mice with 4 x 10 5 whole bone marrow cells. f Levels of donor chimerism in peripheral blood were analyzed at the indicated weeks after transplantation ( n = 3 (Control), 4 (ASXL1-MT)). Data are mean +- s.e.m. g Apoptosis analysis of HSPCs of young Vav-Cre ASXL1-MT KI mice ( n = 7). h Cell cycle analysis with Ki-67/DAPI staining of MPPs (left panel) and LT-HSCs (right panel) of young Vav-Cre ASXL1-MT KI mice ( n = 5). Data are mean +- s.d. unless otherwise noted. * P <= 0.05, ** P <= 0.01, *** P <= 0.001; two-tailed Student's t -test.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_14850_gr1.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Figure 1 ADU-S100 STING agonist reduces tumor burden and activates the pancreatic cancer immune microenvironment. ( A ) Schematic of experimental treatment plan. C57BL/6 mice were implanted into a single-flank with KPC1242 cells and treated with 2 or 3 intratumoral injections of 450 mug DMXAA ( teal ), 1 mug, 10 mug, 25 mug, or 100 mug ADU-S100 (S100, purple ), or vehicle control ( black ). ( B ) Tumors were harvested after 3 injections and measured ex vivo. ( C ) Tumor volume at study end from mice treated twice with dose titration of S100. ( D ) Kaplan-Meier survival curve with log-rank test analysis ( top panel ) and individual animal PDA tumor area ( bottom panel ) over time. Gray arrows indicate treatment on days 11, 15, and 25. n = 4 (control), n = 6 (S100). ( E and F ) Representative gating strategies for flow cytometric analysis of lymphocyte populations ( E ) and myeloid populations ( F ). Shaded regions indicate selected cell populations in gating scheme. ( G ) Tumors from ( B ) were analyzed by flow cytometry. Error bars represent mean +- standard error of the mean (SEM). n = 3-6. FC, fold-change; MFI, median fluorescence intensity; ns, not significant. * P < .05, ** P < .01, *** P < .001, **** P < .0001.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_9863_cells-10-00298-g001.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Figure 1 Characterisation of synovial fibroblasts from the temporomandibular joint of BL/6 mice. Spindle-shaped synovial fibroblasts growing out of the synovial tissue on collagen-I-coated flasks 2 weeks after extraction ( A ). The PCR expression analysis of fibroblast-specific-genes ( B ). Proportion of cells expressing cell-surface fibroblast-specific antigens (CD90.2) and leucocyte-specific antigens (CD45.2, CD11b) in the FACS analysis ( C ).</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_9861_gr4_lrg.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Figure 4 Paquinimod rescues the mice infected by SARS-CoV-2 and MHV (A) A flow chart depicting the process of a drug rescue experiment. (B) Analysis of weight and survival rate of mice infected with SARS-CoV-2 and MHV after Paquinimod treatment. n = 6. (C) Analysis of the rescue effect of Paquinimod by H&E staining and pathology score of lung tissue in mice infected with SARS-CoV-2 or MHV at 5 dpi. Paquinimod treatment significantly prevented the bleeding and fibrosis in lung tissue. A number of pulmonary H&E staining images were randomly selected for pathological scoring. n = 10. Scale bars, 100 mum. (D) Immunohistochemical analysis of the S100A8 + cells in the lung tissue of mice infected with SARS-CoV-2 or MHV at 5 dpi after Paquinimod treatment. The S100A8 + cells in the lungs of mice infected with coronavirus were decreased significantly after Paquinimod treatment. The red arrows indicate the S100A8 + cells. n = 5. Scale bars, 50 mum. (E) qRT-PCR analysis for the expression of S100a8 and Ly6g in the lung of mice infected with SARS-CoV-2 at 5 dpi after Paquinimod treatment. n = 3. (F) qRT-PCR analysis of viral loads in the lungs of mice infected with coronavirus SARS-CoV-2 and MHV at 5 dpi after Paquinimod treatment. n = 3. (G) Flow cytometry analysis of neutrophils in lungs, blood, and bone marrow from mice infected with SARS-CoV-2 at 5 dpi after Paquinimod treatment. CD45 + CD11b + Ly6G variable aberrant neutrophils (P2) in the mice infected with SARS-CoV-2 were signifi</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_9861_gr3_lrg.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Figure 3 A group of immature aberrant neutrophils emerged in coronavirus-infected mice (A) Immunohistochemical analysis of the location and expression of S100A8 in the lung tissue of mice infected with SARS-CoV-2 or MHV at 5 dpi. The S100A8 + cells in the lungs of mice infected with coronavirus were increased significantly. The red arrows indicate the S100A8 + cells. n = 5. Scale bars, 50 mum. (B) Flow cytometry analysis of neutrophils in lungs from mice infected with SARS-CoV-2 and MHV at 5 dpi. Control group means mice treated with vehicle. Gate P1 shows the conventional neutrophils (CD45 + CD11b + Ly6G high ), and Gate P2 shows the pathologic aberrant neutrophils (CD45 + CD11b + Ly6G variable ). Aberrant neutrophils (P2) in the lungs of mice infected with coronavirus were significantly increased. n = 3. (C) Flow cytometry analysis of neutrophils in lungs of mice challenged with IAV, EMCV, HSV-1, and LPS at 5 dpi. The results showed that these treatments did not induce an increase in aberrant neutrophils. n = 3. (D) Flow cytometry analysis of neutrophils in bone marrow from mice infected with SARS-CoV-2 and MHV at 5 dpi. n = 3. (E) qRT-PCR-analyzed related gene expression of aberrant neutrophils in bone marrow of mice infected with MHV at 5 dpi and identified the differentiated types of aberrant neutrophils. n = 3. *** p < 0.001. Error bars, SD.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_14987_nihms-1640051-f0007.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Figure 7: High levels of Hotairm1 in plasma exosomes and MDSCs from late septic patients. (A) Exosomes were purified from plasma and RNA was extracted using exoRNeasy Starter kit. (B) Peripheral blood CD33 + CD11b+HLA-DR - cells were isolated by magnetic cell separation. PBMCs were first purified and depleted of the HLA-DR + cells. The HLA-DR - cell population was then subjected to positive selection with biotin-coupled anti-CD33 antibody, followed by anti-CD11b antibody. Total RNA was extracted using TRIzol reagent. Levels of Hotairm1 were determined by RT-qPCR as in Figure 3 . Values in A were normalized to 18S RNA, and values in B were normalized to GAPDH RNA. Data are expressed as means +- SD of 7-9 subjects/group and are presented relative to HC (1-fold), * p < 0.05, versus HC or early septic; ** p < 0.05, versus late septic. HC, helthy control. (C) S100A9 accumulates in cytosol in CD33+CD11b+HLA-DR - cells during late sepsis. Cytoplasmic and nuclear proteins were extracted from CD33 + CD11b + HLA-DR - cells, and levels of S100A9 were determined by Western blot. The results are representative of two Western blots. (D) Hotairm1 binds S100A9 protein during late sepsis. Cell lysates were prepared from CD33 + CD11b + HLA-DR - cells isolated from late septic patients (n=4) and immunoprecipitated with S100A9 or IgG antibody. S100A9 levels were determined by Western blot. RNA was extracted from S100A9 IP, and Hotairm1 levels were determined by RT-qPCR. Values were normalized to</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_14987_nihms-1640051-f0004.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Figure 4: Knockdown of Hotairm1 in late sepsis MDSCs attenuates their immunosuppressive functions. Gr1 + CD11b + cells were isolated from the bone marrow of late septic mice by positive selection using anti-Gr1 antibody and magnetic beads. The cells were transfected with Hotairm1-specific or scramble siRNAs for 36 hr. (A) Effects of MDSCs on T cell proliferation and activation. CD4 + T cells were isolated from splenocytes of naive mice with anti-CD4 antibody and labeled with the fluorescent dye CFSE. The late sepsis Gr1 + CD11b + cells with Hotairm1 knockdown were then co-cultured (1:1 ratio). T cells were stimulated with anti-CD3 plus anti-CD28 antibodies (1 mug/ml each). After 3 days, the cells were harvested, and T cell proliferation and IFNU production were determined as in Figure 2 . (B and C) Effect of exosomes lacking Hotairm1 on T cells. Late sepsis Gr1 + CD11b + cells with Hotairm1 knockdown were cultured for 24 hr in serum-free media. Culture supernatants were harvested, and exosomes were purified using exoEasy Maxi kit. (B) Levels of Hotairm1 in exosomal RNA was determined by RT-qPCR. Values were normalized to 18S RNA. (C) Spleen CD4 + T cells were labeled and cultured with naive Gr1 + CD11b + cells (as described in Figure 2 ) in the presence of Hotairm1-lacking exosomes. T cell proliferation and IFNU production were measured as in A. Data are expressed as means +- SD of 5-6 mice/group from three experiments. * p < 0.05.KD, knockdown.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_14987_nihms-1640051-f0005.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Figure 5: Hotairm1 binds to S100A9 in late sepsis MDSCs. Gr1 + CD11b + cells were isolated from the bone marrow of late septic mice using anti-Gr1 antibody and magnetic beads. (A) The cells (pooled from 2 mice) were treated with formaldehyde for reversible cross-linking of RNA-protein complexes. Cell lysates were prepared and immunoprecipitated with S100A9 or IgG antibody, and S100A9 levels were determined by western blot. The cross-linked RNA was extracted from the immunoprecipitated complexes using TRIzol reagent, and Hotairm1 levels were determined by standard PCR. (B) Hotairm1 knockdown relocalizes S100A9 in the cytosol. Late sepsis Gr1 + CD11b + cells were transfected with Hotairm1-specific or scramble siRNAs for 36 hr. Cytoplasmic and nuclear proteins were extracted, and levels of S100A9 were determined by Western blot. (C) Ectopic expression of Hotairm1 in early sepsis Gr1 + CD11b + cells moves S100A9 to the nucleus. The cells were transfected with Hotairm1 plasmid or a control vector for 24 hr. Cell lysates were prepared and immunoprecipitated with S100A9 or IgG antibody, and S100A9 levels were determined by Western blot. RNA was extracted from S100A9 IP and Hotairm1 levels were determined by RT-qPCR. Values were normalized to IgG IP samples and presented relative to vector. (D) Protein extracts were prepared, and levels of S100A9 were determined by Western blot. The results are representative of three experiments.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_14987_nihms-1640051-f0003.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Figure 3: Hotairm1 expression is increased in late sepsis MDSCs. Gr1 + CD11b + cells were isolated from the bone marrow of sham and septic mice by positive selection using anti-Gr1 antibody and magnetic beads. (A) The cells were cultured for 24 hr in serum-free media. Exosomes were purified from the culture supernatants, and exosomal RNA was extracted with exoRNeasy Starter kit. Levels of Hotairm1 were determined by RT-qPCR using RT lncRNAqPCR Assay Primers (Qiagen). Values were normalized to 18S RNA. (B) Total RNA was isolated from Gr1 + CD11b + cells using TRIzol reagent, and levels of Hotaim1 were determined as in A. Values were normalized to GAPDH RNA. (C) Gr1 + CD11b + cells isolated from naive mice were cultured for 24 hr without or with exosomes (50 mug/well), purified from late sepsis MDSC culture. The cells were harvested, total RNA was extracted and levels of Hotairm1 were determined as in B. PCR was performed in duplicate. Data are presented relative to sham or media control (1-fold). Data in A and B are expressed as means +- SD of 6-9 mice/group from three experiments. Data in C are expressed as means +- SD of 7 cultures from two experiments. * p < 0.05.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_14987_nihms-1640051-f0006.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Figure 6: Overexpression of Hotairm1 in early sepsis Gr1 + CD11b + cells switches them to the immunosuppressive phenotype. Gr1 + CD11b + cells were isolated from the bone marrow of early septic mice using anti-Gr1 antibody and magnetic beads. The cells were transfected with Hotairm1 expression plasmid or an empty vector and cultured with 10 ng/ml of recombinant mouse IL-10. (A) After 24 hr, a portion of the cells was used for Hotairm1 expression measurement by RT-qPCR. The remainder of the cells were washed and stimulated with 1 mug/ml of of E. coli lipopolysaccharide (serotype 0111:B4; Sigma) for 24 hr. (B) The cells were harvested, lysed and analyzed for arginase activity. (C and D) Levels of IL-10 and TNFalpha in the culture supernatants were measured by ELISA. Data are expressed as means +- SD of 5-6 mice (5-6 cultures/group) from two experiments, * p < 0.05.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_14987_nihms-1640051-f0001.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Figure 1: Exosomes shed from late sepsis MDSCs inhibit LPS-induced secretion of S100A9 protein from early sepsis MDSCs. Gr1 + CD11b + cells were isolated from bone marrow of sham and septic mice by positive selection using anti-Gr1 antibody and magnetic beads. The cells were cultured for 24 hr in serum-free media. Culture supernatants were harvested, and exosomes were purified using exoEasy Maxi kit. Early sepsis Gr1 + CD11b + cells were cultured in 12-well plates with exosomes (50 mug/well) for 24 hr with or without 0.1 mug/ml of E. coli lipopolysaccharide (serotype 0111:B4; Sigma-Aldrich, St. Louis, MO). Levels of S100A9 protein in the culture super natants were measured by ELISA. Data are expressed as means +- SD of 6-8 mice (6-8 cultures/group) from three experiments. * p /** p < 0.05, versus exosomes from sham or early sepsis.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_9936_biomedicines-08-00590-g001.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Figure 1 Phenotype and characterization of HoxB8-Flt3 ligand (FL)-derived myeloid and lymphoid cells. ( A ) Scheme of hematopoietic progenitor cell (HPC) generation using retroviral ER-HoxB8, and differentiation into lymphoid and myeloid cells with indicated quality controls. The scheme was drawn using motifolio drawing toolkits (Copyright (c) motifolio.com; 3 September 2020). ( B ) Growth curve of HoxB8-FL cells (#1: wild-type, #2 Imu-HA-Bcl6 , #3 Cxcr4 WHIM ) with the specified differentiation factors, Estr: estradiol. Error bars represent the standard deviation of three HoxB8-FL cell populations. ( C ) Fluorescence-activated cell scanning (FACS) analysis of undifferentiated HoxB8-FL cells using c-kit expression when cultivated with the specified factors. ( D ) FACS analysis of CD11b and GR1 to identify dendritic cells and granulocytes. ( E ) Co-cultivation with OP9 feeder cells induces differentiation into CD19+/B220+ B cells. ( F ) Principal component analysis of transcriptome profiles of indicated cell lines. ( G ) Cluster analysis of indicated cell lines, based on their transcriptional profile. All biological replicates were performed as technical triplicates.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_14947_urn-x-wiley-07415400-media-jlb10762-jlb10762-fig-0002.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">2 FIGURE CD11b + c-fms + Ly6C hi population accumulate in BM, SPL, and PB following Pg infection . (A) Representative flow cytometry plots and percentage of myeloid cell population in BM of Ctrl and Pg -infected mice. (B) Total cell numbers in BM of Ctrl and Pg -infected mice ( n = 9 for Ctrl group and n = 8 for Pg -infected group in A and B). (C) Representative flow cytometry plots and percentage of myeloid cell populations in SPL of Ctrl and Pg -infected mice. (D) Total cell numbers in SPL of Ctrl and Pg -infected mice ( n = 8 for Ctrl group and n = 7 for Pg -infected group in C and D). (E) Representative flow cytometry plots and percentage of myeloid cell populations in PB of Ctrl and Pg -infected mice. (F) Total cell numbers in PB of Ctrl and Pg -infected mice ( n = 8 for Ctrl group and n = 6 for Pg- infected group in E and F). Data are expressed as mean +- SD. * P < 0.05, ** P < 0.01, *** P < 0.001</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_14951_urn-x-wiley-00071188-media-bph15339-bph15339-fig-0005.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">5 FIGURE Myeloid Pfkfb3 deficiency decreased macrophage infiltration into lungs. (a) Representative images and the quantification of the number of lung IMs and AMs from vehicle and 3PO-treated mice under normoxic or hypoxic (10% O 2 ) conditions. The cell subtypes were identified using flow cytometry defining IMs as CD45 + F4/80 int-hi CD11b high CD11c low and AMs as CD45 + F4/80 int-hi CD11c high CD11b low , n = 5-7. (b) Representative images and quantification of the number of lung IMs and AMs from Pfkfb3 WT or Pfkfb3 DeltaMphi mice under normoxic or hypoxic (10% O 2 ) conditions, n = 6. (c) Representative micrographs ( left ) and quantification of macrophages ( right ) in the lungs of Pfkfb3 WT or Pfkfb3 DeltaMphi mice exposed to normoxia or hypoxia (10% O 2 ) for 4 weeks. N = 6. Sections were co-stained for F4/80 (red), alpha-SMA (green) and DAPI (blue). All data shown are means +- SEM. * P < 0.05, significantly different as indicated; one-way ANOVA followed by Bonferroni test. ns, no significance</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_14944_urn-x-wiley-08941491-media-glia23948-glia23948-fig-0001.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">1 FIGURE The effects of postmortem delay (PMD) on viable fluorescence-activated cell sorting (FACS)-sorted mouse microglia numbers and RNA quality. (a) FACS plots depicting the sorting strategy of DAPI neg Ly6C neg CD11b high CD45 int microglia and the PMD induced decrease in the percentage of DAPI neg microglia in gate R5. (b) Dot plot depicting the number of DAPI neg microglia sorted from entire mouse brains at different PMD times ( n = 4 mice per PMD). (c) Dot plot depicting RIN values of RNA extracted from sorted DAPI neg Ly6C neg CD11b high CD45 int microglia at different PMD times ( n = 4 mice per PMD). A one-way ANOVA followed by a Bonferroni correction for multiple comparisons was performed to assess significance. **, p < .01; ***, p < .001</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_9858_41467_2020_19833_Fig3_HTML.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Fig. 3 m1928z-CD40L CAR T cells stimulate tumor-resident CD11b-CD103- DN cDCs to proliferate, upregulate IRF8, and differentiate to cDC1s. a IRF8 expression in CD11b - CD103 - double-negative (DN) (orange), CD11b - CD103 + cDC1 (green), and CD11b + CD103 + cDC2 (blue) in the tumor of untreated A20.GL tumor-bearing mice. FMO, flow minus one. b - d Ki-67 and IRF8 expression shown as flow cytometry contour plots in CD11b - CD103 - DN cDCs in the tumor ( b ), spleen ( c ), and tumor-draining lymph nodes (tdLN) ( d ) of A20.GL tumor-bearing mice on day 7 after CAR T cell treatment. Percentage of Ki-67 + IRF8 + DN cDCs is summarized from two independent experiments ( n = 7/group). e CD45.2 + A20.GL tumor-bearing mice were treated with 3 x 10 6 CAR T cells i.v. and CD45.2 + CD11b - CD103 - DN cDCs were isolated from the tumor on day 3 by FACS. Sorted CD45.2 + DN cells were cultured in vitro on a CD45.1 + bone-marrow stromal layer for 3 days and the percentage of CD11c + CD103 + cDC1s of all CD45.2 + cells was analyzed. Shown are representative contour plots and the quantification of the percentage of CD11c + CD103 + cDC1s. Each dot represents one in vitro culture. Data were collected from two independently performed experiments (m1928z, n = 5; m1928z-CD40L, n = 6). f , g Ki-67 expression shown as contour plots in CD11b - CD103 + cDC1s ( f ) and CD11b + CD103 - cDC2s ( g ) in the tumor of A20.GL tumor-bearing mice on day 7 after CAR T cell treatment. Percentage of Ki-67 + cells is su</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_9859_elife-60223-fig7.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Figure 7. Macrophages 'eat' dying leukocytes in the injured nerve. ( A ) Cartoon of phagocyte with actin rich phagocytic cup eating a tdTom + apoptotic cell (AC). 'Eat me' signals displayed on the surface of AC allow direct or indirect recognition via engulfment receptors. Following engulfment by phagocytes, AC are digested in the phagolysosome. Cellular cholesterol levels are controlled by upregulation of specific efflux mechanisms. ( B ) scRNAseq dotplot analysis of 'don't eat me' molecules ( Cd47, Sirpa ) and bridging molecules prominently expressed across cell types in the d3 post-SNC nerve. Average gene expression and percentage of cells expressing the gene are shown. ( C ) scRNAseq dotplot analysis of engulfment receptors in the d3 post-SNC nerve. Average gene expression and percentage of cells expressing the gene are shown. ( D ) Flow cytometric analysis of dead cells accumulating in the d3 and d7 nerve (n = 3 biological replicas per time point). Data are represented as mean +- SEM. ( E ) Parabiosis complex of WT (CD45.1) mouse with a (CD45.2) tdTom reporter mouse. ( F ) Flow cytometry dot plot showing tdTom + myeloid cells (CD45.2 + , CD11b + ) in the sciatic nerve of non-parabiotic (tdTom single) mice. ( G ) Flow cytometry dot plot showing tdTom + myeloid cells (CD11b + ) in the sciatic nerve of the WT CD45.1 parabiont. ( H ) Flow cytometry dot plot of CD11b + , tdTom + -gated cells from non-parabiotic (tdTom + single) mice, analyzed for CD45.1 and CD45.2 surface sta</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_9859_elife-60223-fig2.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Figure 2. Immune cell profiles in axotomized DRGs. ( A ) Representative images of L4 DRG cross sections from naive mice, d1, d3, and d7 post-SNC. Macrophages were stained with anti-Iba1 and anti-F4/80. Neurons were stained with anti-NFH. Scale bar, 50 um. ( B ) Quantification of granulocytes per DRG detected by flow cytometry. For flow cytometry of DRGs, naive mice (n = 14 biological replicates), d1 (n = 3), d3 (n = 5), and d7 (n = 12) post-SNC mice were used. Granulocytes (CD45 + , CD11b + , Ly6G + ) per DRG are shown. ( C ) Quantification of Mo/Mac (CD45 + , CD11b + , CD11c - , Ly6G - ) per DRG. ( D ) Quantification of MoDC (CD45 + , CD11b + , CD11c + , Ly6G - ) per DRG. ( E ) Quantification of cDC (CD45 + , CD11b - , CD11c + , Ly6G - ) per DRG. ( F ) Quantification of lymphocytes (CD45+, CD11b - ) per DRG. ( G ) Composition of CD45 + leukocytes in lumbar DRGs identified by flow cytometry. Flow data are represented as mean cell number +- SEM. Each data point represents L3-L5 DRGs pooled from three to four animals (18-24 DRGs), biological replicates, n = 3-14. Statistical analysis was performed in GraphPad Prism (v7) using one-way or two-way ANOVA with correction for multiple comparisons with Tukey's post-hoc test. For B-F, unpaired two-tailed t-test with Welch's correction. A p value < 0.05 (*) was considered significant. p<0.01 (**), p<0.001 (***), and p<0.0001 (****). ( H ) Western blots analysis of DRGs and sciatic nerves (SNs) prepared from sham operated mice and mice a</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_9859_elife-60223-fig6.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Figure 6. Macrophage subpopulation in the injured nerve are functionally distinct and localize to specific sites. ( A-E ) Feature plots of Adgre1 (F4/80), Aif1 (Iba1), Cd68 (Scavenger receptor class D) , Cx3cr1 (Fractalkine receptor), and CD209a (DC-SIGN) expression in the d3 post-SNC nerve. ( F ) scRNAseq dot plot analysis of transcription regulators (TRs) enriched in leukocytes. Average gene expression and percentage of cells expressing the TR are shown. ( G ) Violin plot of Ly6c2 (Ly6C) expression in immune cells of the d3 post-SNC nerve. ( H-K ) Flow cytometric analysis of sciatic nerve Mo/Mac (CD45 + , CD11b + , Ly6G - , CD11c - ) in naive mice, d1, d3, and d7 post-SNC mice. Mo/Mac maturation was assessed by Ly6C surface staining. ( L, M ) Quantification of Ly6C distribution on Mo/Mac in naive nerves and at different post-SNC time points (n = 11 biological replicates per time point); ( L ) Percentile of Ly6C - , Ly6C int , and Ly6C hi Mo/Mac and ( M ) number of Ly6C - , Ly6C int , and Ly6C hi Mo/Mac. Flow data are represented as mean +- SEM. Statistical analysis was performed in GraphPad Prism (v7) using one-way or two-way ANOVA with correction for multiple comparisons with Tukey's post-hoc test. A p value < 0.05 (*) was considered significant. p<0.01 (**), p<0.001 (***), and p<0.0001 (****). ( N ) Feature plot showing Arg1 (Arginase-1) expression in the 3d post-SNC nerve. ( O-Q ) Longitudinal sciatic nerve sections of Arg1-YFP reporter mice, from naive mice ( O ), d3 (</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_9859_elife-60223-fig3.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Figure 3. Sciatic nerve injury triggers massive accumulation of hematogenous leukocytes in the injured nerve but not axotomized DRGs. ( A ) Parbiosis complex of a wildtype (WT) and a tdTomato (tdTom) mouse. Mice were surgically paired at postnatal day 56. The timeline of the experiment is shown. ( B ) Flow cytometric analysis of sciatic nerve trunks collected from non-parabiotic (single) tdTom mice, WT parabionts, and tdTom parabionts. Dotplot of live (CD11b + , tdTom + ) cells in the d3 post-SNC nerve. ( C ) Quantification of tdTom + myeloid cells in the 3d injured nerve of WT single mice (WT-S), WT parabiont (WT-para), tdTom parabiont (tdTom-para), and tdTom single (tdTom-S) mice. The fraction of tdTom + myeloid cells (CD45 + , CD11b + ), MoDC (CD45 + , CD11b + , CD11c + , Ly6G - ), and Mo/Mac (CD45 + , CD11b + , CD11c - , Ly6G - ) is shown. For quantification of tdTom + immune cells, nerves from the WT parabiont and the tdTom parabiont were harvested separately (three mice per data point) with n = 2-3 biological replicates. Flow data are represented as fraction of tdTom + cells +- SEM. Statistical analysis was performed in GraphPad Prism (v8) using one-way ANOVA with correction for multiple comparisons with Tukey's post-hoc test. p value of < 0.001 (***) and p<0.0001 (****). ( D ) Longitudinal sciatic nerves sections of the WT parabiont at d7 post-SNC. The nerve crush site is marked with a white dotted line, proximal is to the left, distal to the right. Anti-F4/80 (green)</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_9857_41419_2020_3223_Fig3_HTML.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Fig. 3 ZD55-IL-24 inhibits melanoma growth in B16-bearing immunocompetent mouse model mainly through the indirect pathway of inducing systemic antitumor immunity. A , B Changes of the immune-related cytokines in tumors treated with ZD55-IL-24. A Heat-map of the down-regulated immunosuppressive cytokines in Fig. 2 C . B Heat-map of the up-regulated immunostimulatory cytokines in Fig. 2 D . C - J Immunohistochemical analysis of immune cell infiltration in tumors, as well as recruitment and activation in spleens. Tumors and spleens resected from B16-bearing C57BL/6 mice receiving PBS or ZD55-IL-24 treatment indicated in Fig. 1 A were analyzed 2 days after the last injection by immunohistochemical staining. C Shown are representative images of tumor sections immunostained for CD8 (red, left panel), CD11b and Ly-6G (yellow, middle panel), and NK1.1 (red, right panel). D Quantification of the CD8 + cells in C ( n = 11). E Quantification of the CD11b + Ly-6G + Ly-6C low neutrophils in C ( n = 3). f Quantification of the NK1.1 + cells in c ( n = 6). G Quantification of the CD8 + cells in H ( n = 9). H Shown are representative images of spleen sections immunostained for CD8 (red, left panel), CD11b and Ly-6G (yellow, middle panel), and NK1.1 (red, right panel). I Quantification of the CD11b + Ly-6G + Ly-6C low neutrophils in H ( n = 3). j Quantification of NK1.1 + cells in h ( n = 9). Nuclei is counterstained with DAPI (blue). Data are mean +- SD. Scale bars, 300 um. Shown is one of t</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_9854_fimmu-11-574839-g001.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Figure 1 CD11b + Gr-1 + myeloid-derived suppressor cells (MDSCs) increase in the liver after sublethal acetaminophen (APAP) challenge. (A) Representative staining of CD11b + Gr-1 + cells. (B) The frequencies of CD11b + Gr-1 + cells in different compartments enumerated at 7 days or 14 days after APAP treatment. Naive control group was healthy mice without any treatment (n=10-18 per group). *P < 0.05, **P < 0.01, ***P < 0.001. Kruskal-Wallis test. (C) Absolute cell numbers of CD11b + Gr-1 + cells in the liver. *P < 0.05, ***P < 0.001, NS, no significance, Kruskal-Wallis test. (D) The suppressive abilities of CD11b + Gr-1 + cells sorted either from the liver or the spleen at 7 days after APAP pretreatment, Mann-Whitney test. Data were expressed as mean +- SD.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_14973_13287_2020_2014_Fig1_HTML.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Fig. 1 Characterization of murine BMMSCs. a , b Flow cytometric analysis of the surface markers showed positive expression of CD29, CD90, CD105, CD146, and Sca-1, and negative expression of hematopoietic markers CD11b, CD34, and CD45. c Representative image of colony formation of murine BMMSCs. d Representative image of Oil Red O staining of murine BMMSCs. e Representative image of ALP staining of murine BMMSCs. f Representative image of Alizarin red staining of murine BMMSCs. Scale bar, 500 mum</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_9856_cancers-12-03457-g003.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Figure 3 Osteosarcoma cell-derived extracellular-vesicles (EVs) promote accumulation of bone marrow-derived cells in the lungs. ( A ) Schematic illustration of the experimental setup. Mice were treated with either PBS, 143-B EVs or SAOS-2 EVs (10 µg) 2 times a week for 3 weeks after which mice were euthanized. ( B ) Relative mRNA expression levels of integrin alpha M gene encoding CD11b ( Itgam ) in bulk lung RNA in mice of indicated treatment groups. Transcript levels are normalized to Gapdh and expressed as fold change relative to control mice. n = 6, mice were pooled from two independent experiments indicated in red and black ( C ) Representative flow cytometric profile (left panel) and quantification (right panel) of CD11b + cells isolated from lungs of mice from indicated treatment groups; n = 3 mice per group. ( D ) Representative immunofluorescence images (left panel) and quantification (right panel) of CD11b + cells (red) and nuclei (blue) in lungs of mice from indicated treatment groups. Scale bar, 500 um. (*, p < 0.05, **, p < 0.01, ***, p = 0.0001, ****, p < 0.0001, Bonferroni's one-way ANOVA test).</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_9862_aging-12-104176-g004.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Figure 4 Atg7 deletion accelerates the aging of CD11b + Ly6G - myeloid cells. ( A ) Flow cytometric analysis of ROS levels of CD11b + Ly6G - cells with fluorescent DCFH-DA. Left, histogram for flow cytometric assessment of CD11b + Ly6G - cells; right, geometric mean fluorescence intensity (MFI) of DCFH-DA in CD11b + Ly6G - cells of wild-type mice and atg7-deleted mice. ( B ) Flow cytometric analysis of mitochondrial mass levels of CD11b + Ly6G - cells with florescent MitoTracker Deep Red. Left, histogram for the flow cytometric assessment of CD11b + Ly6G - cells; right, geometric MFI of MitoTracker Deep Red in CD11b + Ly6G - cells of wild-type and atg7-deleted mice. ( C ) Gene expression heatmap of cell death negative regulators. ( D ) Analysis of apoptosis in CD11b + Ly6G - cells of wild-type mice and Atg7-deleted mice by Annexin V and PI double staining. Left, representative flow cytometric measurement; right, statistical results from cytometric analysis. Early apoptosis, Annexin V + PI - ; late apoptosis, Annexin V + PI + (right)</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_9862_aging-12-104176-g003.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Figure 3 Atg7-deletion accumulated histone H3.1 protein with incorrect cytoplasmic localization in the bone marrow CD11b + Ly6G - myeloid cells. ( A , C ). Western blotting analysis of histone H3.1 in bone marrow cells. Gapdh or total histone H3 was used as a loading control. ( A ) Mononuclear cells; ( C ) CD11b + Ly6G - and CD11b + Ly6G + myeloid cells. ( B , D ) Flow cytometric analysis of protein level of histone H3.1 in bone marrow cells. ( B ) Analysis of histone H3.1 in CD11b - and CD11b + bone marrow cells. ( D ) Analysis of histone H3.1 in CD11b + Ly6G - and CD11b + Ly6G + myeloid cells. Right, scheme for analysis of histone H3.1 in bone marrow cells. Left, statistical analysis of histone H3.1 geometric mean fluorescence intensity (MFI) in bone marrow cells. ( E ) Western blotting analysis of histone H3.1 in cytoplasm and nucleus from mononuclear cells. ( F ). Confocal detection of histone H3.1 protein in CD11b + Ly6G - myeloid cells. ( G ) Ratio of geometric mean of H3K9/14/18Ac compared to H3.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_9862_aging-12-104176-g001.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Figure 1 Atg7 deletion diminishes the cellularity of bone marrow CD11b + myeloid cells. ( A - D ) Graphical and statistical analysis of CD11b and Ly6G by flow cytometry in the bone marrow cells of wild-type and Atg7 or Atg5 hematopoietic-specific deleted mice. ( A , C ) Number of CD11b + Ly6G - and CD11b + Ly6G + myeloid cells in the bone marrow of wild-type and Atg7 or Atg5-deleted mice. ( B , D ) Percentage of CD11b + Ly6G - and CD11b + Ly6G + myeloid cells in the bone marrow of wild-type and Atg7 or Atg5-deleted mice. ( E , F ) Percentage of CD11b + and CD11b - myeloid cells in the bone marrow of wild-type and Atg7 or Atg5-deleted mice. ( G , H ) Percentage of Ly6G + and Ly6G - myeloid cells in CD11b + myeloid cells from the bone marrow of wild-type and Atg7 or Atg5-deleted mice.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_19023_fimmu-11-536442-g002.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Heterozygous deletion of A20 results in myeloid-biased hematopoiesis. (A) Outline of experiments utilizing WT (VavCre + or RosaCreER + ) and A20 +/- (A20 +/- VavCre + or A20 +/- RosaCreER + ) mice for colony progenitor function and PB analysis. (B) A20 mRNA expression by qRT-PCR in lineage negative BM (Lin- BM) cells from VavCre+ and A20+/-VavCre+ mice (n = 3 mice per group). (C) A20 protein expression by immunoblotting in Lin- BM cells from VavCre+ and A20+/-VavCre+ mice (pooled from two mice). ( D ) Colony formation in methylcellulose of BM LSK cells isolated from WT RosaCreER + and A20 +/- RosaCreER + mice (treated with tamoxifen). One-tailed T test from three mice per group. (E) Complete blood counts for WT (VavCre + ; n = 3) and heterozygous A20-deficient (A20 +/- VavCre + ; n = 6) mice at the indicated time points post BM transplantation. *P < 0.05. (F) Flow cytometric analysis of donor-derived (CD45.2 + ) myeloid cells (CD11b + ) in the PB from recipient mice reconstituted with BM from VavCre + (n = 7) or A20 -/- VavCre + BM cells (n = 7) (CD45.2 + ) at the indicated time points post-transplantation. (G) Flow cytometric analysis of donor-derived (CD45.2 + ) myeloid cells (CD11b + ) and lymphoid cells (CD3 + and B220 + ) in the PB from recipient mice reconstituted with BM from VavCre + or A20 -/- VavCre + BM cells (CD45.2 + ) at 16 weeks post-transplantation.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_14974_jciinsight-5-135775-g143.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Figure 5 Trophectoderm overexpression of Hyal-2 resulted in enhanced implantation rate but early embryonic lethality. Implantation sites were studied at E6.5, containing sham-infected embryos and embryos overexpressing Hyal-2 in their trophoblast. ( A ) H&E staining ( n = 6 dams; white arrows indicate decidua). ( B ) TUNEL staining revealed cell death at the embryonic niche of Hyal-2 OEx (white arrow indicate embryonic cells; n = 4 dams). ( C and D ) Quantification of observed decidua, as well as their calculated area (2.9 +- 0.5; 4.75 +- 0.7; P = 0.02) ( n = 12 dams in control, n = 10 dams in Hyal-2 OEx) divided by (3.42-fold change+- 0.07; 0.03; P = 0.0006) ( n = 8 dams, 27 implantation sites in control; n = 6 dams, 23 implantation sites for Hyal-2 OEx). ( E and F ) Detection of MAC-2 + macrophages and their quantification (5.9-fold change +- 0.35; P = 0.02) ( n = 5 dams, 9 decidua in each group). ( G ) Presence of MAC-2 + macrophages was further demonstrated using immunostaining of macrophages in implantation sites harvested from surrogate mothers injected with rhodamine-labeled (ROX-labeled) lectin. Tissues were made transparent using modified tissue clearing procedure, thus enabling visualization of whole decidua by confocal microscopy. ( n = 2 dams from each group). ( H ) Flow cytometry analysis of CD11b + F4/80 + cells in E6.5 decidua (12.33 +- 0.31 [control]; 17.02 +- 1.49 [overexpression]; P = 0.04) ( n = 3 dams in control, n = 5 dams in Hyal-2 OEx). The statistical</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_9860_nihms-1651551-f0006.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">FIGURE 6. Lipin-1 contributes to efferocytosis. ( A ) WT and KO mice subjected to an excisional wound-healing model. Number of macrophages/dead cells was analyzed via flow cytometry. ( B ) BMDMs from WT and KO mice were subjected to a dual-label in vitro model of continuing efferocytosis, and percentage of macrophages (CD11b + and F4/80 + ) that took up an initial event (primary) and multiple apoptotic bodies (continuing) were analyzed via flow cytometry. WT, EKO ( C ), and KO ( D ) mice were subjected to a zymosan model of peritonitis followed by peritoneal injection of PHK26-labeled AC. Percentage of macrophages (CD11b + , F4/80 + , PKH26 + , and Ly6G - ) with labeled AC were analyzed via flow cytometry. Graphed data represent mean uptake with SEM. Student t test was used to analyze data. n = 8-12. * p <= 0.5.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_9851_fimmu-11-01856-g0002.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Figure 2 Partial loss of PTPN2 increases cDC2 accumulation in skin and liver. (A) Representative flow cytometry plots for identification of CD11b + cDC1s (brown) and CD24 + cDC2s (green). (B) IRF4 and IRF8 expression in cDC1s and cDC2s. (C) Pie charts of the proportion of cDC1s and cDC2s across tissues in young (5-weeks-old) PTPN2 fl/fl (WT) and PTPN2 fl/fl x CD11c Cre (KO) mice. (D-F) Frequencies of cDC subset distribution in 5-weeks-old (D) , 13-weeks-old (E) , and 22-weeks-old (F) mice. Data are representative of two independent experiments with n >= 4 mice (C-F) . * p < 0.05 [two-tailed Mann Whitney test (D-F) ]. Data are shown as mean +- s.d. (D-F) .</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_12509_41467_2020_18491_Fig2_HTML.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Fig. 2 Gdpd3 maintains the self-renewal capacity of CML stem cells in vivo. a Survival rates of retro-CML-affected mice in a primary BMT experiment that received BCR-ABL1/EGFP-transduced LSK cells from either Gdpd3 +/+ mice (one male, one female) or Gdpd3 -/- mice (two females). Results shown are cumulative data obtained from two biologically independent experiments ( P -value, Log-rank non-parametric test). b The survival rate of second-round BMT recipient mice that received serial transplantation of BCR-ABL1/EGFP + CML-LSK cells (3 x 10 4 cells) isolated from either the Gdpd3 +/+ retro-CML-affected mice (14 females) or Gdpd3 -/- retro-CML-affected mice (15 females) as in a . Results shown are cumulative data obtained from three biologically independent experiments. Mouse survival was monitored for 90 days. ( P -value, Log-rank non-parametric test) c - f Absolute numbers of BCR-ABL1/EGFP + CML-LSK cells isolated from c , e BM of the two hind limbs and d , f spleen of Gdpd3 +/+ retro-CML-affected mice and Gdpd3 -/- retro-CML-affected mice after c , d a first-round or e , f second-round of serial BM transplantation. Data are the mean absolute numbers +- s.d. of BCR-ABL1/EGFP + LSK cells. n numbers in a - f indicate biologically independent mouse numbers. ( P -value, unpaired two-sided Student''s t -test). (See also Supplementary Fig. 6). g , h Cell cycle distribution of CML-LSK cells in the spleen of Gdpd3 +/+ retro-CML-affected mice (three females) or Gdpd3 -/- retro-CML-affe</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_9853_41598_2020_72181_Fig1_HTML.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Figure 1 Flow-cytometric analysis of the wild-type adult cochlea indicates the presence of innate and adaptive immune cells. Panels shows the gating strategy for flow-cytometric analysis of the immune cells in control spleen ( A ) and cochleae ( B ) of C57BL/6J mice. A gate was first set from the forward-scatter versus side-scatter dot-plot of all events in the area that corresponded to the size and granularity of lymphocytes using a spleen as a reference. The cells in the lymphocyte gate were then plotted as forward scatter versus Live-Dead stain. The cells in the live gate were then examined in a plot comparing the forward-scatter width and side-scatter area; cells inside the gate were determined to be single cells (singlets). The cells within the singlet gate were then plotted as a histogram of CD45 expression. Live CD45 + cells in the sample were further analyzed for B, T, NK, and myeloid cells and myeloid cells were further gated for macrophages and neutrophils depending on their surface-markers as described in methods section. Representative dot-plots from control C57BL/6 mouse spleen ( C ) and cochlea ( D ) shows various CD45 + immune cells including B, T, NK, and myeloid cells, macrophages and neutrophils with their respective surface expression of B220, CD3e, NK1.1, CD11b, CX3CR1, and Ly6G respectively. The numbers on the dot-plots shows the percentages of cells gated in the corresponding dot-plot. The numbers showed in the plots for B, T, NK, and myeloid cells are p</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_9832_41467_2020_18039_Fig1_HTML.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Fig. 1 Dendritic cells from old mice exhibit an activated phenotype and promote Th1 and Th17 T cell responses. Single cell suspensions of lymph nodes and spleens from old and young C57BL/6 mice were labeled with anti-CD11c, anti-CD11b, anti-MHC class II, anti-CD40, anti-CD80, and anti-CD86. a The frequency of CD11b + CD11c + DCs in lymph nodes ( p = 0.0006) and spleens ( p = 0.0023), and b the expression of costimulatory molecules (MHC-II: p = 0.0005/CD40: p < 0.0001/CD80: p = 0.0035/CD86: p = 0.0007) by splenic DCs were assessed by flow cytometry. c Proliferative capacities of CD4 + ( p = 0.0079) and CD8 + T cells ( p = 0.0079) co-cultured with DCs from old and young mice were determined using CFSE dilution and viability assessed using propidium iodide ( d ) CD4 + T cells from young mice were co-cultured with CD11b + CD11c + DCs isolated from young and old mice and ( e ) pro-inflammatory cytokine expression was assessed by flow cytometry (IL-17: p = 0.0002/IFN-gamma: p = 0.0013) and ELISA (Il-17: p = 0.004/IFN-gamma: p = 0.0079); ( n = 7 biologically independent animals), results are representative of at least three independent experiments. Column plots display mean with standard deviation. Statistical significance was determined by using two-tailed Mann-Whitney-test. Asterisks indicate p values * p <= 0.05, ** p <= 0.01, and *** p <= 0.001, only significant values are shown. Source data are provided as a Source Data file.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_9817_jciinsight-5-136773-g165.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Figure 1 Lymphocytes make up the main immune population within digested GCT. Viable single tumor cell suspension and PBMCs from healthy donors were analyzed using polychromatic flow cytometry and progressive gating strategy. ( A ) Representative staining with CD3, CD4, CD8, CD25, CD45, and FOXP3 used to quantify helper (CD4 + ), cytotoxic (CD8 + ), and regulatory (Tregs) (CD4 + CD25 + FOXP3 + ) T cells in a GCT sample. ( B-D ) Representative staining with CD11b, HLA-DR, CD11c, Lineage, CD14, CD15, and CD33 used to identify the myeloid populations in a GCT sample. Tumor-associated macrophages (TAMs)/monocytes were separated from DC based on CD14 expression ( C ). Myeloid-derived suppressor cells (MDSC) were separated as eMDSC based on Lineage, HLA-DR, CD11b, and CD33 markers ( B ), whereas PMN-MDSC were characterized as CD15 + CD14 - CD11b + ( D ). Proportions of tumor-infiltrating immune cells in GCT were quantified as percentage of total cell suspension. ( E ) Percentages of CD4 + T cells, CD8 + T cells, and Tregs compared with total tumor cell suspension. ( F ) Comparison of PD1-expressing T cells in the GCT vs. PBMCs. ( G ) CD8 + T cells/Tregs ratio in GCT vs. PBMCs. ( H ) Percentage of TAMs/monocytes, DC, PMN-MDSC, and eMDSC of total tumor cell suspension. Mean +- SEM is shown. Each dot represents a patient ( n = 7) or healthy control PBMCs ( n = 3).</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_9852_cancers-12-02083-g004.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Figure 4 Population of CD11b + myeloid progenitor cells differentiate into SMA + stromal cells within tumors and in vitro. ( A ) Representative image of red fluorescent protein (RFP) + stromal cells in tumor from CCR2-RFP heterozygous SCID mouse. ( B ) RFP + SMA + double positive cells within tumor stroma. ( C ) CD11b + SMA + double positive cells within tumor stroma. ( D ) CD45 + CD11b + CD34+ myeloid progenitor cells in the mammary gland at 1.5 ( n = 5 empty vector (EV), 7 CCL2) and 2.5 weeks ( n = 5 EV, 7 CCL2) post-transplantation were quantified by flow cytometry. ( E ) CD45 + CD11b + CD34 + myeloid progenitor cells in the bone marrow at 1.5 weeks ( n = 6 EV, 7 CCL2) and 2.5 weeks ( n = 3 mice/group) post-transplantation were quantified by flow cytometry. ( F ) Representative brightfield image of colony formed by CD45 + CD11b + CD34 + myeloid progenitor cells isolated using fluorescence-activated cell sorting (FACS). ( G ) Colonies in culture co-stained with SMA and collagen I. Statistical differences determined by Mann-Whitney U test. Magnification bars = 50 um.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_9852_cancers-12-02083-g002.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Figure 2 Stromal CCL2 overexpression in mouse mammary glands leads to time-dependent changes in the developing tumor microenvironment. ( A ) Representative H&E images of oncogenic epithelial cell growth at 1.5 and 2.5 weeks post-transplantation. ( B ) Percent area of F4/80 + macrophages in developing tumors at 1.5 and 2.5 weeks post-transplantation ( n = 4 tumors/group; Student's t -test). ( C ) CD45 + CD11b + monocytes/macrophages in the mammary gland at 1.5 and 2.5 weeks post-transplantation were quantified by flow cytometry ( n = 5 EV, 7 CCL2, Mann-Whitney U test). ( D ) Percent area of SMA + cells in developing tumors at 1.5 and 2.5 weeks post-transplantation ( n = 4 tumors/group; Student's t -test). Magnification bars = 50 um.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_14971_cells-09-01634-g005.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Figure 5 Effects of compounds 5 and 7 on in vivo chemotaxis of CD11b + Ly6G + , CD11b + F4/80 + and CD11b - CD3 + cells. ( A ) Neutrophil content of pouches from mice given a vehicle injection (top left), an LPS injection (top right), an LPS injection and compound 5 (bottom left) or an LPS injection and compound 7 (bottom right). Flow cytometry plots represent the distribution of live cells based on surface CD11b and Ly6G staining; ( B ) analysis of the percentage of neutrophils (CD11b+Ly6G+) recruited to air pouches; ( C ) total number of neutrophils (CD11b+Ly6G+) migrated to subdermal air pouches; ( D ) macrophage content of pouches from mice given a vehicle injection (top left), an LPS injection (top right), an LPS injection and compound 5 (bottom left) or an LPS injection and compound 7 (bottom right). Flow cytometry plots represent the distribution of live cells based on surface CD11b and F4/80 staining; ( E ) analysis of the percentage of macrophages (CD11b+F4/80+) recruited to air pouches. ( F ) Total number of macrophages (CD11b+F4/80+) migrated to subdermal air pouches. ( G ) Analysis of the percentage of T-cells (CD11b-CD3+) recruited to air pouches. ( H ) Total number of T-cells (CD11b-CD3+) migrated to subdermal air pouches. Air pouches contain compound 5 (5 ug) and compound 7 (5 ug) in the presence or absence of LPS (2 ug). Each data point represents a single mouse ( n = 7-10). * p < 0.05, ** p < 0.01. Bars represent mean values. Data were pooled from three indep</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_8339_fimmu-11-00787-g005.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">FIGURE 5 Loss of lipin-1 does not alter systemic immune responses. (A) Splenocytes and (B) blood cells were stained with a panel of antibodies to quantify monocyte/macrophage and PMN populations. Myeloid populations were defined as CD45 + , CD3 - CD19 - CD11b + . PMNs were CD11b + Ly6g + and monocytes were CD11b + Ly6G - . Each dot represents an individual animal. Experiment was performed twice (mean +- SEM). (C) Cytometric bead arrays to quantify cytokine concentrations in serum taken from mice 2 days after wounding Each dot represents an individual animal. Experiment was performed twice (mean +- SEM).</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_9849_41419_2020_2546_Fig4_HTML.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Fig. 4 cGAS-STING signaling is required for the pro-metastatic effect of irradiated MSCs. a MSCs were transfected with siRNA for 24 h and then cultured for another 24 h after irradiation (12 Gy). The expression levels of cGAS in MSCs were determined by real-time PCR. MSCs were transfected with siRNA for 24 h and then cultured for another 48 h after irradiation (12 Gy). The expression levels of cGAS were analyzed by western blotting. b MSCs were transfected with siRNA for 24 h and then cultured for another 24 h after irradiation (12 Gy). The expression levels of STING in MSCs were determined by real-time PCR. MSCs were transfected with siRNA for 24 h and then cultured for another 48 h after irradiation (12 Gy). The expression levels of STING were analyzed by western blotting. c , d MSCs transfected with sicGAS or siSTING for 24 h were cultured for another 24 h after irradiation (12 Gy). The expression level of Ccl5 was determined by qPCR. e , i MSCs (1 x 10 4 ) were transfected with siRNA for 24 h and then cultured for another 24 h after irradiation (12 Gy). These cells were co-injected with 4T1 cells (5 x 10 4 ) into BALB/c mice via tail vein. Metastatic nodules were counted after 14 days ( e ). Single-cell suspensions prepared from lung tissues were analyzed for the frequency of CD11b + F4/80 + macrophages ( f - g ), CD4 + T cells ( h ) and CD8 + T cells ( i ) by flow cytometry. n >= 3 for each group. All experiments in this figure were repeated at least three times. * p < 0</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_14970_cells-09-01106-g003.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Figure 3 Stronger anti-inflammatory changes in the composition of immune modulatory cells in CD62L -/- mice during steatohepatitis-inducing diets. ( A ) Serum aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels of wild type (WT) and CD62L -/- animals after chow, 4 weeks MCD or 24 weeks HFD treatment. (* p < 0.05). ( B ) Total numbers of intrahepatic neutrophils were analysed by FACS. Cells were gated by FSC/SSC; duplets were excluded. Live/CD45 + , CD11b + /Ly6G + were regarded as neutrophils (* p < 0.05). ( C ) Total cell numbers of intrahepatic CD11b + /F4/80 + cells were analysed by FACS. Cells were gated by FSC/SSC; duplets were excluded. Live/CD45 + , then gated on CD11b + and F4/80 + (** p < 0.01). ( D ) Intrahepatic CD4 + /CTLA4 + T cells were analysed by FACS. CD4 + /CTLA4 + T cells were gated by FSC/SSC, duplets were excluded, Live/CD45 + , CD4 + /CTLA4 + . A statistical analysis of the amount of CD4 + /CTLA4 + cells of recorded CD45 + cells was performed. (* p < 0.05, ** p < 0.01). ( E ) Intrahepatic CD25 + /FoxP3 + cells were analysed by FACS. Cells were gated by FSC/SSC, duplets were excluded, Live/CD45 + , CD4 + , CD25 + /FoxP3 + . A statistical analysis of the percentage of CD25 + /FoxP3 + of recorded CD45 + cells was performed. Whole livers of chow, MCD and HFD fed WT and CD62L -/- mice were analysed for FoxP3 mRNA expression via RT-qPCR (** p < 0.01, *** p < 0,001) and values expressed as fold induction over the mean values obtained for</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_14970_cells-09-01106-g006.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Figure 6 Therapeutic intervention with a CD62L blocking antibody results in dampened pro-inflammatory changes and stronger anti-oxidative stress responses in liver. ( A ) Representative H&E images or ( B ) Oil Red O stains of livers from WT mice after 6 w MCD with or without peritoneal administration of an isotype control antibody or a CD62L blocking antibody from week 4-6 after MCD feeding (400x, scale bars 50 um). ( C ) Intrahepatic CD11b + /F4/80 + cells were analysed by FACS after 6 w MCD with or without peritoneal administration of an isotype control antibody or a CD62L blocking antibody from week 4-6 after MCD feeding. Cells were gated by FSC/SSC; duplets were excluded. Live/CD45+, then gated on CD11b + and F4/80 + (* p < 0.05). Intrahepatic neutrophils were analysed by FACS in the same groups. Cells were gated by FSC/SSC; duplets were excluded. Live/CD45 + , CD11b + /Ly6G + were regarded as neutrophils (*** p < 0.001). ( D ) Hepatic IL-6 and TNF-alpha, ( E ) Nrf and HO-1, ( F ) alpha-SMA and TGF-beta mRNA expression was analysed in the same groups via RT-qPCR. Values are expressed as fold induction over the mean values obtained for WT mice treated with MCD diet for 6 weeks (* p < 0.05, ** p < 0.01). All data are expressed as mean +- SEM ( n = 4). All experiments were repeated at least twice.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_12622_41598_2020_64158_Fig3_HTML.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Figure 3 Physiological abundance of Ly6c Lo non-classical monocytes compared to Ly6c Hi classical monocytes in the late gestation fetal liver. ( a ) Ly6c Lo monocytes, Ly6c Hi monocytes, and other leukocyte populations were identified by flow cytometry. ( b,c ) The overall proportion of Cd45 + leukocytes is relatively low in the late gestational fetal liver (E17.5, n = 11), then increases by day of birth (P0, n = 9), and plateaus (P3, n = 6; P7, n = 9; P10, n = 6; P14, n = 7), whereas the proportion in the spleen stays relatively stable (P0, n = 6; P3, n = 6; P7, n = 9; P10, n = 6; P14, n = 7. ( d,e ) Cd11b + monocytes were identified and are at their highest abundance of the Cd45 + leukocyte compartment in the late gestational liver (E17.5, n = 11). They then decrease at birth (P0, n = 6), rise again to a level that is between the two earlier time points (P3, n = 6; P7, n = 9), and then decrease to day of birth levels (P10, n = 6; P14, n = 4). In the spleen, Ly6c Lo non-classical monocytes remained low at birth and peaked at P7. (f-g) There is a physiological abundance of Ly6c Lo non-classical monocytes compared to Ly6c Hi classical monocytes at E17.5 in the liver that is not observed in the spleen (p-value % : <0.0001 (****), p-value # : 0.0007 (***)). Data represent mean +/- SEM.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_12621_BMRI2020-5417201.009.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Figure 9 The count of MDSC and ratio of M-MDSC/G-MDSC in BMNC after fluid resuscitation by HES. #: compared to control, P < 0.05; MDSC: myeloid-derived suppressor cell; M-MDSC: monocytic MDSC; G-MDSC: granulocytic/neutrophilic MDSC; BMNC: suspension and bone marrow nucleated cells; HES: hydroxyethyl starch.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_12621_BMRI2020-5417201.008.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Figure 8 The count of MDSC and ratio of M-MDSC/G-MDSC in BMNC after fluid resuscitation by HTS. #: compared to control, P < 0.05; MDSC: myeloid-derived suppressor cell; M-MDSC: monocytic MDSC; G-MDSC: granulocytic/neutrophilic MDSC; BMNC: suspension and bone marrow nucleated cells; HTS: hypertonic saline.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_12621_BMRI2020-5417201.007.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Figure 7 The count of MDSC and ratio of M-MDSC/G-MDSC in BMNC after fluid resuscitation by NS. #: compared to control, P < 0.05; MDSC: myeloid-derived suppressor cell; M-MDSC: monocytic MDSC; G-MDSC: granulocytic/neutrophilic MDSC; BMNC: suspension and bone marrow nucleated cells; NS: normal saline.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_12621_BMRI2020-5417201.002.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Figure 2 The count of MDSC and ratio of M-MDSC/G-MDSC in PBNC after fluid resuscitation by HTS. #: compared to control, P < 0.05; MDSC: myeloid-derived suppressor cell; M-MDSC: monocytic MDSC; G-MDSC: granulocytic/neutrophilic MDSC; PBNC: peripheral blood nucleated cells; HTS: hypertonic saline.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_12621_BMRI2020-5417201.001.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Figure 1 The count of MDSC and ratio of M-MDSC/G-MDSC in PBNC after fluid resuscitation by NS. #: compared to control, P < 0.05; MDSC: myeloid-derived suppressor cell; M-MDSC: monocytic MDSC; G-MDSC: granulocytic/neutrophilic MDSC; PBNC: peripheral blood nucleated cells; NS: normal saline.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_12621_BMRI2020-5417201.006.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Figure 6 The count of MDSC and ratio of M-MDSC/G-MDSC in the spleen after fluid resuscitation by HES. #: compared to control, P < 0.05; MDSC: myeloid-derived suppressor cell; M-MDSC: monocytic MDSC; G-MDSC: granulocytic/neutrophilic MDSC; HES: hydroxyethyl starch.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_12621_BMRI2020-5417201.005.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Figure 5 The count of MDSC and ratio of M-MDSC/G-MDSC in the spleen after fluid resuscitation by HTS. #: compared to control, P < 0.05; MDSC: myeloid-derived suppressor cell; M-MDSC: monocytic MDSC; G-MDSC: granulocytic/neutrophilic MDSC; HTS: hypertonic saline.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_12621_BMRI2020-5417201.003.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Figure 3 The count of MDSC and ratio of M-MDSC/G-MDSC in PBNC after fluid resuscitation by HES. #: compared to control, P < 0.05; M-MDSC: monocytic MDSC; G-MDSC: granulocytic/neutrophilic MDSC; PBNC: peripheral blood nucleated cells; HES: hydroxyethyl starch.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/tfs_12621_BMRI2020-5417201.004.jpg?time=20240507?time=20240507" alt="CD11b Antibody in Flow Cytometry (Flow)" title="CD11b Antibody (15-0112-82) in Flow"> <figcaption itemprop="caption">Figure 4 The count of MDSC and ratio of M-MDSC/G-MDSC in the spleen after fluid resuscitation by NS. #: compared to control, P < 0.05; MDSC: myeloid-derived suppressor cell; M-MDSC: monocytic MDSC; G-MDSC: granulocytic/neutrophilic MDSC; NS: normal saline.</figcaption> </figure> </div> </div> </noscript> <div id="tf-related-products-container-new"></div> <div class="product-details"> <div class="container"> <div class="row"> <div class="large-span-12 medium-span-12 small-span-12"> <h2 class="pdp-sub-heading product_details_heading">Product Details</h2></div> <div class="hidden-sku"> <h2>15-0112-82</h2> </div> <div class="product-detail-section tested-app-section new-tbl-design product-detail-section table-spec"> <div class="product-container-head"> <div class="product-item"> Applications </div> <div class="product-item dilution-lbl-head "> Tested Dilution </div> <div class="product-item published-applications"> Publications </div> </div> <div class="product-container-body"> <div class="product-item"> <h2>Immunocytochemistry (ICC/IF)</h2></div> <div class="product-item "> <span class="dilution-lbl dilution-lbl-dash">-</span> </div> <div class="product-item"> <a class="animated-scroll" onclick="window.THERMO_FISHER.pdp.inp.handleClickReferenceProductDetails(event,this,'a[href="#ICCIF-content&quot]')" data-target="References" href="#references-component-id"> <span class="desktop-view">View 2 publications</span> <span class="mobile-view">2 publications</span></a> </div> </div> <div class="product-container-body"> <div class="product-item"> <h2>Flow Cytometry (Flow)</h2></div> <div class="product-item "> <span class="dilution-lbl">0.125 µg/test</span> </div> <div class="product-item"> <a class="animated-scroll" onclick="window.THERMO_FISHER.pdp.inp.handleClickReferenceProductDetails(event,this,'a[href="#Flow-content&quot]')" data-target="References" href="#references-component-id"> <span class="desktop-view">View 287 publications</span> <span class="mobile-view">287 publications</span></a> </div> </div> </div> <div class="product-detail-section tested-app-section new-tbl-design product-specific-section table-spec"> <div class="product-container-head"> <div class="product-item">Product Specifications</div> </div> <div class="product-container-body pcb1-2"> <div class="product-item"> <h2>Species Reactivity</h2> </div> <div class="product-item left-flex-cls"> <span title="Mus musculus">Mouse</span> </div> </div> <div class="product-container-body pcb1-2"> <div class="product-item"> <h2>Published species</h2> </div> <div class="product-item left-flex-cls"> <span>Fish,</span> <span>Human,</span> <span>Mouse</span> </div> </div> <div class="product-container-body pcb1-2"> <div class="product-item"> <h2> Host/Isotype</h2> </div> <div class="product-item left-flex-cls"> <span title="Rattus">Rat / IgG2b, kappa</span> </div> </div> <div class="product-container-body pcb1-2"> <div class="product-item"> <h2>Recommended Isotype Control</h2> </div> <div class="product-item left-flex-cls"> <a href="//www.thermofisher.com/antibody/product/15-4031-82"> Rat IgG2b kappa Isotype Control (eB149/10H5), PE-Cyanine5, eBioscience™</a> </div> </div> <div class="product-container-body pcb1-2"> <div class="product-item"> <h2>Class</h2> </div> <div class="product-item left-flex-cls"> <div class="product-value"> Monoclonal </div> </div> </div> <div class="product-container-body pcb1-2"> <div class="product-item"> <h2>Type</h2> </div> <div class="product-item left-flex-cls"> <div class="product-value"> Antibody </div> </div> </div> <div class="product-container-body pcb1-2"> <div class="product-item"> <h2>Clone</h2> </div> <div class="product-item left-flex-cls"> <div class="product-value"> M1/70 </div> </div> </div> <div class="product-container-body pcb1-2"> <div class="product-item"> <h2>Conjugate</h2> </div> <div class="product-item left-flex-cls"> <a ng-if="$ctrl.checkConjugate('PE-Cyanine5 ') && ''.trim() != ''" href="" ng-attr-target="{{$ctrl.getRequestCustomLinkTarget()}}" class="conjugate-value">PE-Cyanine5 </a> <span ng-if="($ctrl.checkConjugate('PE-Cyanine5 ') && ''.trim() == '')" class="conjugate-value">PE-Cyanine5 </span> <span ng-if="!$ctrl.checkConjugate('PE-Cyanine5 ')" class="conjugate-value">PE-Cyanine5 </span> <div class="dropdown conjugate-dropdown"> <button class="btn-link conjugate-btn" type="button" data-toggle="dropdown"> View additional formats <span class="caret"></span> </button> <ul class="dropdown-menu dropdown-menu-fixed"> <li><a class="conjugate-color-padding" href="/antibody/product/14-0112-82"> Unconjugated <span class="conjugate-indicator" style="background-color:"></span> </a></li> <li><a class="conjugate-color-padding" href="/antibody/product/53-0112-82"> Alexa Fluor 488 <span class="conjugate-indicator" style="background-color:#36FF00"></span> </a></li> <li><a class="conjugate-color-padding" href="/antibody/product/58-0112-82"> Alexa Fluor 532 <span class="conjugate-indicator" style="background-color:#B3FF00"></span> </a></li> <li><a class="conjugate-color-padding" href="/antibody/product/606-0112-82"> Alexa Fluor 660 <span class="conjugate-indicator" style="background-color:#DB0000"></span> </a></li> <li><a class="conjugate-color-padding" href="/antibody/product/56-0112-82"> Alexa Fluor 700 <span class="conjugate-indicator" style="background-color:#8D0000"></span> </a></li> <li><a class="conjugate-color-padding" href="/antibody/product/17-0112-82"> APC <span class="conjugate-indicator" style="background-color:#DB0000"></span> </a></li> <li><a class="conjugate-color-padding" href="/antibody/product/47-0112-82"> APC-eFluor 780 <span class="conjugate-indicator" style="background-color:#808080"></span> </a></li> <li><a class="conjugate-color-padding" href="/antibody/product/13-0112-82"> Biotin <span class="conjugate-indicator" style="background-color:"></span> </a></li> <li><a class="conjugate-color-padding" href="/antibody/product/363-0112-82"> Brilliant UV 395 <span class="conjugate-indicator" style="background-color:#8000A1"></span> </a></li> <li><a class="conjugate-color-padding" href="/antibody/product/364-0112-82"> Brilliant UV 496 <span class="conjugate-indicator" style="background-color:#00FFFF"></span> </a></li> <li><a class="conjugate-color-padding" href="/antibody/product/365-0112-82"> Brilliant UV 563 <span class="conjugate-indicator" style="background-color:#C3FF00"></span> </a></li> <li><a class="conjugate-color-padding" href="/antibody/product/366-0112-82"> Brilliant UV 615 <span class="conjugate-indicator" style="background-color:#FF8900"></span> </a></li> <li><a class="conjugate-color-padding" href="/antibody/product/376-0112-82"> Brilliant UV 661 <span class="conjugate-indicator" style="background-color:#DB0000"></span> </a></li> <li><a class="conjugate-color-padding" href="/antibody/product/367-0112-82"> Brilliant UV 737 <span class="conjugate-indicator" style="background-color:#808080"></span> </a></li> <li><a class="conjugate-color-padding" href="/antibody/product/368-0112-82"> Brilliant UV 805 <span class="conjugate-indicator" style="background-color:#808080"></span> </a></li> <li><a class="conjugate-color-padding" href="/antibody/product/404-0112-82"> Brilliant Violet 421 <span class="conjugate-indicator" style="background-color:#5400FF"></span> </a></li> <li><a class="conjugate-color-padding" href="/antibody/product/414-0112-82"> Brilliant Violet 480 <span class="conjugate-indicator" style="background-color:#00C0FF"></span> </a></li> <li><a class="conjugate-color-padding" href="/antibody/product/406-0112-82"> Brilliant Violet 605 <span class="conjugate-indicator" style="background-color:#FFAD00"></span> </a></li> <li><a class="conjugate-color-padding" href="/antibody/product/416-0112-82"> Brilliant Violet 650 <span class="conjugate-indicator" style="background-color:#DB0000"></span> </a></li> <li><a class="conjugate-color-padding" href="/antibody/product/407-0112-82"> Brilliant Violet 711 <span class="conjugate-indicator" style="background-color:#820000"></span> </a></li> <li><a class="conjugate-color-padding" href="/antibody/product/417-0112-82"> Brilliant Violet 786 <span class="conjugate-indicator" style="background-color:#808080"></span> </a></li> <li><a class="conjugate-color-padding" href="/antibody/product/48-0112-82"> eFluor 450 <span class="conjugate-indicator" style="background-color:#0028FF"></span> </a></li> <li><a class="conjugate-color-padding" href="/antibody/product/69-0112-82"> eFluor 506 <span class="conjugate-indicator" style="background-color:#00FF54"></span> </a></li> <li><a class="conjugate-color-padding" href="/antibody/product/50-0112-82"> eFluor 660 <span class="conjugate-indicator" style="background-color:#DB0000"></span> </a></li> <li><a class="conjugate-color-padding" href="/antibody/product/11-0112-82"> FITC <span class="conjugate-indicator" style="background-color:#1FFF00"></span> </a></li> <li><a class="conjugate-color-padding" href="/antibody/product/16-0112-82"> Functional Grade <span class="conjugate-indicator" style="background-color:"></span> </a></li> <li><a class="conjugate-color-padding" href="/antibody/product/M015T02B01-A"> NovaFluor Blue 510 <span class="conjugate-indicator" style="background-color:#00FF00"></span> </a></li> <li><a class="conjugate-color-padding" href="/antibody/product/M015T02B04-A"> NovaFluor Blue 585 <span class="conjugate-indicator" style="background-color:#FFEF00"></span> </a></li> <li><a class="conjugate-color-padding" href="/antibody/product/M015T02B05-A"> NovaFluor Blue 610-30S <span class="conjugate-indicator" style="background-color:#FF8900"></span> </a></li> <li><a class="conjugate-color-padding" href="/antibody/product/M015T02B07-A"> NovaFluor Blue 660-40S <span class="conjugate-indicator" style="background-color:#DB0000"></span> </a></li> <li><a class="conjugate-color-padding" href="/antibody/product/M015T02R03"> NovaFluor Red 700 <span class="conjugate-indicator" style="background-color:#8D0000"></span> </a></li> <li><a class="conjugate-color-padding" href="/antibody/product/M015T02Y01-A"> NovaFluor Yellow 570 <span class="conjugate-indicator" style="background-color:#E1FF00"></span> </a></li> <li><a class="conjugate-color-padding" href="/antibody/product/M015T02Y02-A"> NovaFluor Yellow 590 <span class="conjugate-indicator" style="background-color:#FFDF00"></span> </a></li> <li><a class="conjugate-color-padding" href="/antibody/product/M015T02Y04-A"> NovaFluor Yellow 660 <span class="conjugate-indicator" style="background-color:#DB0000"></span> </a></li> <li><a class="conjugate-color-padding" href="/antibody/product/12-0112-82"> PE <span class="conjugate-indicator" style="background-color:#F0FF00"></span> </a></li> <li><a class="conjugate-color-padding" href="/antibody/product/25-0112-82"> PE-Cyanine7 <span class="conjugate-indicator" style="background-color:#808080"></span> </a></li> <li><a class="conjugate-color-padding" href="/antibody/product/61-0112-82"> PE-eFluor 610 <span class="conjugate-indicator" style="background-color:#FF9B00"></span> </a></li> <li><a class="conjugate-color-padding" href="/antibody/product/45-0112-82"> PerCP-Cyanine5.5 <span class="conjugate-indicator" style="background-color:#DB0000"></span> </a></li> <li><a class="conjugate-color-padding" href="/antibody/product/46-0112-82"> PerCP-eFluor 710 <span class="conjugate-indicator" style="background-color:#820000"></span> </a></li> <li><a class="conjugate-color-padding" href="/antibody/product/62-0112-82"> Super Bright 436 <span class="conjugate-indicator" style="background-color:#3D00FF"></span> </a></li> <li><a class="conjugate-color-padding" href="/antibody/product/63-0112-82"> Super Bright 600 <span class="conjugate-indicator" style="background-color:#FFBE00"></span> </a></li> <li><a class="conjugate-color-padding" href="/antibody/product/64-0112-82"> Super Bright 645 <span class="conjugate-indicator" style="background-color:#DB0000"></span> </a></li> <li><a class="conjugate-color-padding" href="/antibody/product/67-0112-82"> Super Bright 702 <span class="conjugate-indicator" style="background-color:#8D0000"></span> </a></li> <li><a class="conjugate-color-padding" href="/antibody/product/78-0112-82"> Super Bright 780 <span class="conjugate-indicator" style="background-color:#808080"></span> </a></li> <li class="drop-down-link-ctnr"> <a class="conjugate-dropdown-link" href="/us/en/home/global/forms/antibody-conjugates-custom-form.html" ng-attr-target="$ctrl.getRequestCustomLinkTarget()">Request custom conjugation <svg class="svg-icon external-link-icon" ng-if="$ctrl.showExternalLinkIcon()"> <use href="#external-link"></use> </svg> </a> </li> </ul> </div> </div> </div> <div class="product-container-body pcb1-2"> <div class="product-item"> <h2>Excitation/Emission Max</h2> </div> <div class="product-item left-flex-cls"> <span>568/666 nm</span> <a target="_blank" class="spectra-view" href="/order/fluorescence-spectraviewer?SID=srch-svtool&UID=pe_cy5"> <span class="view-spectra"> View spectra</span> <span class="spectra-view-icon "><img src="/order/genome-database/assets/img/spectra.png" alt="spectra"/></span> </a> </div> </div> <div class="product-container-body pcb1-2"> <div class="product-item"> <h2>Form</h2> </div> <div class="product-item left-flex-cls"> <div class="product-value"> Liquid </div> </div> </div> <div class="product-container-body pcb1-2"> <div class="product-item"> <h2>Concentration</h2> </div> <div class="product-item left-flex-cls"> <div class="product-value"> 0.2 mg/mL </div> </div> </div> <div class="product-container-body pcb1-2"> <div class="product-item"> <h2>Purification</h2> </div> <div class="product-item left-flex-cls"> <div class="product-value"> Affinity chromatography </div> </div> </div> <div class="product-container-body pcb1-2"> <div class="product-item"> <h2>Storage buffer</h2> </div> <div class="product-item left-flex-cls"> <div class="product-value"> PBS, pH 7.2 </div> </div> </div> <div class="product-container-body pcb1-2"> <div class="product-item"> <h2>Contains</h2> </div> <div class="product-item left-flex-cls"> <div class="product-value"> 0.09% sodium azide </div> </div> </div> <div class="product-container-body pcb1-2"> <div class="product-item"> <h2>Storage conditions</h2> </div> <div class="product-item left-flex-cls"> <div class="product-value"> 4° C, store in dark, DO NOT FREEZE! </div> </div> </div> <div class="product-container-body pcb1-2"> <div class="product-item"> <h2>Shipping conditions</h2> </div> <div class="product-item left-flex-cls"> <div class="product-value"> Ambient (domestic); Wet ice (international) </div> </div> </div> <div class="product-container-body pcb1-2"> <div class="product-item"><h2>RRID <span id="rrid-tooltip" class="rrid-tooltip-icon" ng-include="'/order/genome-database/webapp/assets/core/img/svg/mono_tooltip.svg'" data-toggle="tooltip" ng-click="$ctrl.showRridTooltip()" close-tooltip="$ctrl.closeRridTooltip()" title="Research Resource Identifiers (#RRID) are ID numbers assigned to help researchers cite key resources in the biomedical literature to improve transparency of research methods."> </span></h2> </div> <div class="product-item left-flex-cls">AB_468714</div> </div> </div> <div class="product-specific-details"> <div class="product-specific-details-tbl product-specific-add-border" > <div class="product-info-para"> <h4 class="product-info-para-heading"> Product Specific Information </h4> <p>Description: The M1/70 monoclonal antibody reacts with mouse CD11b, the 165-170 kDa integrin alphaM. CD11b non-covalently associates with CD18 to form alphaM-beta2 integrin (Mac-1) and binds to CD54 (ICAM-1), C3bi, and fibrinogen. Mac-1 is expressed by macrophages, NK cells, granulocytes, activated lymphocytes and mouse B-1 cells in the peritoneal cavity. M1/70 is also cross-reactive to human CD11b, and can be used for the detection of this antigen on human peripheral blood monocytes, granulocytes, and a subset of NK cells. Through interactions with its ligands, CD11b participates in adhesive cell interactions.<br /><br />Applications Reported: The M1/70 antibody has been reported for use in flow cytometric analysis.<br /><br />Applications Tested: The M1/70 antibody has been tested by flow cytometric analysis of mouse splenocytes and bone marrow cells. This can be used at less than or equal to 0.125 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.<br /><br />Light sensitivity: This tandem dye is sensitive photo-induced oxidation. Please protect this vial and stained samples from light. <br /><br />Fixation: Samples can be stored in IC Fixation Buffer (<a href="https://www.thermofisher.com/order/catalog/product/00-8222-49">Product # 00-822-49</a>) (100 µL cell sample + 100 µL IC Fixation Buffer) or 1-step Fix/Lyse Solution (<a href="https://www.thermofisher.com/order/catalog/product/00-5333-54">Product # 00-5333-54</a>) for up to 3 days in the dark at 4°C with minimal impact on brightness and FRET efficiency/compensation. Some generalizations regarding fluorophore performance after fixation can be made, but clone specific performance should be determined empirically.<br /><br />Excitation: 488-561 nm; Emission: 667 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser.<br /><br />Filtration: 0.2 µm post-manufacturing filtered.</p> </div> <div class="product-info-para"> <h4 class="product-info-para-heading"> Target Information </h4> <p class="product-specific-target-info">CD11b (integrin alpha-M, ITGAM, integrin alpha-X, ITGAX) is a 165 kDa adhesion molecule that associates non-covalently with integrin beta-2 (CD18). The CD11b/CD18 heterodimeric complex is also known as integrin alpha-M beta-2, Mac-1, and CR3 (complement receptor 3). CD11b is expressed on the surface of monocytes/macrophages, granulocytes, activated lymphocytes, a subset of NK cells, a subset of dendritic cells, and microglia in the brain. CD11b/CD18 functions as the receptor for ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), CD14, CD50, CD23, heparin, iC3b, fibrinogen, and Factor X -these adhesions are critical for cell-cell and cell-matrix interactions. CD11b is expressed on 8% of spleen cells, 44% of bone marrow cells, and less than 1% of thymocytes, and is commonly used as a microglial marker in nervous tissue. The expression of CD11b increases during monocyte maturation and expression levels vary on tissue macrophages. Further, peritoneal macrophages are reported to express higher levels of CD11b than splenic macrophages. Diseases associated with CD11b dysfunction include systemic lupus erythematosus 6 and ITGAM-related susceptibility to systemic lupus erythematosus.</p> </div> <p class="product-details-regulatoryStmt">For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.</p> </div> <div class="product-detail-panel-builder"> <tf-promo-ad ng-if="$ctrl.showPromoAd" show-promo-ad="$ctrl.showPromoAd"></tf-promo-ad> <div class="product-detail-video"> <div tf-video-player-new video-id="6206990159001" player-width="368" player-height="210"></div> <div class="panel-builder"> <h4 class="product-info-para-heading"> How to use the Panel Builder </h4> <p>Watch the video to learn how to use the Invitrogen Flow Cytometry Panel Builder to build your next flow cytometry panel in 5 easy steps.</p> </div> </div> </div> </div> </div> </div> </div> <div id="rootPdpDocLoader"></div> <div id="tf-related-products-container" ng-show="emptyRelatedProductsWidget === false" > <related-products-container ng-if="showRelatedProductsWidget === true" base-url="'/api/magellan/related-products-ui/widget/v2/'" product-type="'antibody'" product-sub-type="'primary'" product-id="'15-0112-82'" country-code="'sg'" iso-language="'en'" > </related-products-container> </div> <div class="tf-pdp-divider" ng-if="emptyRelatedProductsWidget === false" ></div> <div class="references reference-section-2" id="references-component-id"> <div id="references-section-id"> <reference-section ng-if="loadReferences" default-display-card-limit="3" reference-count="289" sub-type="'Antibody'" application-data='{"citationApplications":[{"applicationAbbreviation":"ICC/IF","citations":[{"title":"Tracking the elusive fibrocyte: identification and characterization of collagen-producing hematopoietic lineage cells during murine wound healing.","summary":"Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry","authors":"Suga H,Rennert RC,Rodrigues M,Sorkin M,Glotzbach JP,Januszyk M,Fujiwara T,Longaker MT,Gurtner GC","literatureId":"24446236","journal":"Stem cells (Dayton, Ohio)","volume":"32","pageNumber":"1347","publishedDate":"May 1, 2014, 4:00:00 AM","url":"http://dx.doi.org/10.1002/stem.1648","benchSci":false,"imageURL":"https://www.thermofisher.com/antibody/images/250/null?time\u003d20240507","journalAbbr":"Stem Cells","sortOrder":243,"species":["Mouse"],"speciesDilutionMap":{"Mouse":"Not Cited"},"abbreviationToNameMap":{"ICC/IF":"Immunocytochemistry","Flow":"Flow Cytometry"},"newSpeciesDilutionMap":{"Mouse~Flow~Not Cited":""}},{"title":"Pluripotency factors functionally premark cell-type-restricted enhancers in ES cells.","summary":"15-0112 was used in Immunocytochemistry-Immunofluorescence to examine the hierarchical and obligate premarking of cell-type-restricted enhancers in embryonic stem cells.","authors":"Kim HS,Tan Y,Ma W,Merkurjev D,Destici E,Ma Q,Suter T,Ohgi K,Friedman M,Skowronska-Krawczyk D,Rosenfeld MG","literatureId":"29670286","journal":"Nature","volume":"556","pageNumber":"510","publishedDate":"Apr 1, 2018, 4:00:00 AM","url":"http://dx.doi.org/10.1038/s41586-018-0048-8","benchSci":false,"imageURL":"https://www.thermofisher.com/antibody/images/250/null?time\u003d20240507","journalAbbr":"Nature","sortOrder":113,"species":["Mouse"],"speciesDilutionMap":{"Mouse":"Not Cited"},"abbreviationToNameMap":{"ICC/IF":"Immunocytochemistry"},"newSpeciesDilutionMap":{"Mouse~ICC/IF~Not Cited":""}}],"citationsCount":2,"speciesList":["Mouse"],"journals":["Stem Cells","Nature"],"speciesMap":{"Mouse":2},"journalsMap":{"Stem Cells":1,"Nature":1},"sortedMap":{}},{"applicationAbbreviation":"Flow","citations":[],"citationsCount":287,"speciesList":["Human","Mouse","Fish"],"journals":["NPJ Vaccines","Brain","Mol Med Rep","Nat Commun","J Transl Med","Alcohol Clin Exp Res","Dis Model Mech","Blood","Stem Cells","Nat Neurosci","Nat Med","Arterioscler Thromb Vasc Biol","J Autoimmun","Development","Am J Blood Res","Nat Cell Biol","Acta Ophthalmol","PLoS One","J Cell Biochem","Dev Cell","RNA Biol","Dev Biol","Aging (Albany NY)","J Am Soc Nephrol","J Neuroinflammation","J Ginseng Res","Biology (Basel)","J Appl Toxicol","J Cereb Blood Flow Metab","Bioact Mater","Redox Biol","Mater Today Bio","Elife","PLoS Genet","Shock","J Immunol","Anticancer Drugs","Hepatology","J Leukoc Biol","Physiol Rep","Iran J Basic Med Sci","JCI Insight","Oncoimmunology","Chonnam Med J","Biomed Res Int","Adv Mater","iScience","Nature","Stem Cell Reports","J Clin Cell Immunol","Front Physiol","J Immunol Methods","Br J Pharmacol","Cancer Cell","J Clin Invest","Adv Sci (Weinh)","Nanomicro Lett","PLoS Biol","Cell Stem Cell","J Cell Physiol","Nat Metab","Commun Biol","Proc Natl Acad Sci U S A","Int J Nanomedicine","J Bone Miner Res","Breast Cancer Res","Sci Adv","Exp Mol Med","Oncotarget","Immunity","Int J Mol Med","Stem Cells Int","Cell","Stem Cells Transl Med","Cancer Res","Immunohorizons","Cancers (Basel)","Acta Pharm Sin B","PLoS Negl Trop Dis","STAR Protoc","Cell Host Microbe","Stem Cell Res Ther","Clin Cancer Res","Sci Rep","Arthritis Rheum","Biomedicines","Endocrinology","Exp Parasitol","EMBO J","Cell Mol Immunol","Int J Mol Sci","Nat Immunol","J Exp Med","Chem Biol","Cell Rep","Cell Microbiol","Exp Ther Med","Cell Death Dis","J Virol","J Neuroimmunol","Immunology","J Immunother Cancer","Eur J Immunol","J Comp Neurol","J Hematol Oncol","Mol Med","Tissue Eng Part A","Front Immunol","J Neurotrauma","Mucosal Immunol","Front Pharmacol","Theranostics","Cells","J Reprod Dev","Pain Res Manag","Am J Physiol Gastrointest Liver Physiol","PLoS Pathog","Cell Mol Gastroenterol Hepatol","J Biol Chem","Glia","Mol Cancer","Part Fibre Toxicol"],"speciesMap":{"Human":4,"Mouse":66,"Fish":1},"journalsMap":{"NPJ Vaccines":1,"Brain":1,"Mol Med Rep":4,"Nat Commun":24,"J Transl Med":1,"Alcohol Clin Exp Res":1,"Dis Model Mech":1,"Blood":3,"Stem Cells":1,"Nat Neurosci":3,"Nat Med":3,"Arterioscler Thromb Vasc Biol":1,"J Autoimmun":1,"Development":1,"Am J Blood Res":1,"Nat Cell Biol":1,"Acta Ophthalmol":1,"PLoS One":14,"J Cell Biochem":2,"Dev Cell":1,"RNA Biol":1,"Dev Biol":1,"Aging (Albany NY)":3,"J Am Soc Nephrol":2,"J Neuroinflammation":3,"J Ginseng Res":1,"Biology (Basel)":1,"J Appl Toxicol":1,"J Cereb Blood Flow Metab":1,"Bioact Mater":1,"Redox Biol":1,"Mater Today Bio":1,"Elife":1,"PLoS Genet":1,"Shock":1,"J Immunol":5,"Anticancer Drugs":1,"Hepatology":1,"J Leukoc Biol":2,"Physiol Rep":1,"Iran J Basic Med Sci":1,"JCI Insight":8,"Oncoimmunology":4,"Chonnam Med J":1,"Biomed Res Int":2,"Adv Mater":1,"iScience":1,"Nature":7,"Stem Cell Reports":2,"J Clin Cell Immunol":1,"Front Physiol":1,"J Immunol Methods":1,"Br J Pharmacol":3,"Cancer Cell":1,"J Clin Invest":9,"Adv Sci (Weinh)":2,"Nanomicro Lett":1,"PLoS Biol":1,"Cell Stem Cell":2,"J Cell Physiol":2,"Nat Metab":1,"Commun Biol":1,"Proc Natl Acad Sci U S A":4,"Int J Nanomedicine":1,"J Bone Miner Res":2,"Breast Cancer Res":1,"Sci Adv":1,"Exp Mol Med":1,"Oncotarget":5,"Immunity":5,"Int J Mol Med":1,"Stem Cells Int":1,"Cell":5,"Stem Cells Transl Med":1,"Cancer Res":1,"Immunohorizons":1,"Cancers (Basel)":3,"Acta Pharm Sin B":1,"PLoS Negl Trop Dis":1,"STAR Protoc":2,"Cell Host Microbe":2,"Stem Cell Res Ther":2,"Clin Cancer Res":1,"Sci Rep":8,"Arthritis Rheum":1,"Biomedicines":1,"Endocrinology":1,"Exp Parasitol":1,"EMBO J":1,"Cell Mol Immunol":1,"Int J Mol Sci":1,"Nat Immunol":4,"J Exp Med":1,"Chem Biol":1,"Cell Rep":4,"Cell Microbiol":1,"Exp Ther Med":1,"Cell Death Dis":6,"J Virol":2,"J Neuroimmunol":1,"Immunology":1,"J Immunother Cancer":2,"Eur J Immunol":2,"J Comp Neurol":1,"J Hematol Oncol":1,"Mol Med":1,"Tissue Eng Part A":1,"Front Immunol":13,"J Neurotrauma":1,"Mucosal Immunol":2,"Front Pharmacol":3,"Theranostics":1,"Cells":5,"J Reprod Dev":1,"Pain Res Manag":1,"Am J Physiol Gastrointest Liver Physiol":1,"PLoS Pathog":1,"Cell Mol Gastroenterol Hepatol":4,"J Biol Chem":8,"Glia":8,"Mol Cancer":1,"Part Fibre Toxicol":1},"sortedMap":{}}]}'></reference-section> </div> <noscript> <div itemscope itemtype="https://schema.org/ScholarlyArticle"> <h2>Product References</h2> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/37781363"> <div itemprop="name">Deciphering the mechanism of <i>Peptostreptococcus anaerobius</i>-induced chemoresistance in colorectal cancer: the important roles of MDSC recruitment and EMT activation.</div> </a> <div itemprop="about">Frontiers in immunology</div> <div itemprop="author">Gu J,Lv X,Li W,Li G,He X,Zhang Y,Shi L,Zhang X</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Tue Oct 03 00:00:00 EDT 2023</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/37177863"> <div itemprop="name">Exogenous IL-10 posttreatment along with TLR4 and TNFR1 blockade improves tissue antioxidant status by modulating sepsis-induced macrophage polarization.</div> </a> <div itemprop="about">Journal of applied toxicology : JAT</div> <div itemprop="author">Sawoo R,Dey R,Ghosh R,Bishayi B</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Sun Oct 01 00:00:00 EDT 2023</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/37586249"> <div itemprop="name">Gene deletion of long-chain acyl-CoA synthetase 4 attenuates xenobiotic chemical-induced lung injury via the suppression of lipid peroxidation.</div> </a> <div itemprop="about">Redox biology</div> <div itemprop="author">Tomitsuka Y,Imaeda H,Ito H,Asou I,Ohbayashi M,Ishikawa F,Kuwata H,Hara S</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Sun Oct 01 00:00:00 EDT 2023</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/37791323"> <div itemprop="name">Intranasal Delivery of Endothelial Cell-Derived Extracellular Vesicles with Supramolecular Gel Attenuates Myocardial Ischemia-Reperfusion Injury.</div> </a> <div itemprop="about">International journal of nanomedicine</div> <div itemprop="author">Wang J,Tan Y,Dai Y,Hu K,Tan X,Jiang S,Li G,Zhang X,Kang L,Wang X,Xu B</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Thu Oct 05 00:00:00 EDT 2023</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/37744359"> <div itemprop="name">The Cxcr2<sup>+</sup> subset of the S100a8<sup>+</sup> gastric granylocytic myeloid-derived suppressor cell population (G-MDSC) regulates gastric pathology.</div> </a> <div itemprop="about">Frontiers in immunology</div> <div itemprop="author">Kao KD,Grasberger H,El-Zaatari M</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Fri Sep 29 00:00:00 EDT 2023</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/37841583"> <div itemprop="name">Targeting adrenergic receptors to mitigate invariant natural killer T cells-induced acute liver injury.</div> </a> <div itemprop="about">iScience</div> <div itemprop="author">Gonzatti MB,Freire BM,Antunes MM,de Menezes GB,Talbot J,Peron JPS,Basso AS,Keller AC</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Fri Oct 20 00:00:00 EDT 2023</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/37828009"> <div itemprop="name">Perinatal murine cytomegalovirus infection reshapes the transcriptional profile and functionality of NK cells.</div> </a> <div itemprop="about">Nature communications</div> <div itemprop="author">Rožmanić C,Lisnić B,Pribanić Matešić M,Mihalić A,Hiršl L,Park E,Lesac Brizić A,Indenbirken D,Viduka I,Šantić M,Adler B,Yokoyama WM,Krmpotić A,Juranić Lisnić V,Jonjić S,Brizić I</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Thu Oct 12 00:00:00 EDT 2023</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/36914206"> <div itemprop="name">LAL deficiency induced myeloid-derived suppressor cells as targets and biomarkers for lung cancer.</div> </a> <div itemprop="about">Journal for immunotherapy of cancer</div> <div itemprop="author">Zhao T,Liu S,Hanna NH,Jalal S,Ding X,Wan J,Yan C,Du H</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Wed Mar 01 00:00:00 EST 2023</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/37589156"> <div itemprop="name">Cellular Membrane-Engineered Nanovesicles as a Three-Stage Booster to Target the Lesion Core.</div> </a> <div itemprop="about">Advanced materials (Deerfield Beach, Fla.)</div> <div itemprop="author">Huang F,Du Y,Chen Y,Qiu Z,Wang Z,Fan Y,Shi Y,Li Z,Yang K,Cui W,Jin W</div> <div itemprop="description">15-0112-82 was used in Flow Cytometry to demonstrate that a three-stage booster nanovesicle, constructed through the double emulsion-extrusion method and incorporating a neutrophil membrane, functional antibody, and gelled drug-loaded core, enables targeted delivery of catestatin for ischemic cardiomyopathy therapy.</div> <div itemprodp="datePublished">Wed Nov 01 00:00:00 EDT 2023</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/36901755"> <div itemprop="name">Topical Diacerein Decreases Skin and Splenic CD11c<sup>+</sup> Dendritic Cells in Psoriasis.</div> </a> <div itemprop="about">International journal of molecular sciences</div> <div itemprop="author">Brunner SM,Ramspacher A,Rieser C,Leitner J,Heil H,Ablinger M,Tevini J,Wimmer M,Koller A,Piñón Hofbauer J,Felder TK,Bauer JW,Kofler B,Lang R,Wally V</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Tue Feb 21 00:00:00 EST 2023</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/36828819"> <div itemprop="name">CD11c<sup>+</sup> microglia promote white matter repair after ischemic stroke.</div> </a> <div itemprop="about">Cell death & disease</div> <div itemprop="author">Jia J,Zheng L,Ye L,Chen J,Shu S,Xu S,Bao X,Xia S,Liu R,Xu Y,Zhang M</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Fri Feb 24 00:00:00 EST 2023</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/36592421"> <div itemprop="name">Group 2 Innate Lymphoid Cells Protect Mice from Abdominal Aortic Aneurysm Formation via IL5 and Eosinophils.</div> </a> <div itemprop="about">Advanced science (Weinheim, Baden-Wurttemberg, Germany)</div> <div itemprop="author">Zhang Y,Liu T,Deng Z,Fang W,Zhang X,Zhang S,Wang M,Luo S,Meng Z,Liu J,Sukhova GK,Li D,McKenzie ANJ,Libby P,Shi GP,Guo J</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Wed Mar 01 00:00:00 EST 2023</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/37169762"> <div itemprop="name">Single-cell sequencing reveals homogeneity and heterogeneity of the cytopathological mechanisms in different etiology-induced AKI.</div> </a> <div itemprop="about">Cell death & disease</div> <div itemprop="author">Chen Z,Li Y,Yuan Y,Lai K,Ye K,Lin Y,Lan R,Chen H,Xu Y</div> <div itemprop="description">15-0112-82 was used in Flow Cytometry to provide a potent resource for understanding the pathogenesis of acute kidney injury AKI and early intervention in AKI progression at single-cell resolution.</div> <div itemprodp="datePublished">Thu May 11 00:00:00 EDT 2023</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/36873191"> <div itemprop="name">Anti-PD-L1 antibody enhances curative effect of cryoablation <i>via</i> antibody-dependent cell-mediated cytotoxicity mediating PD-L1<sup>high</sup>CD11b<sup>+</sup> cells elimination in hepatocellular carcinoma.</div> </a> <div itemprop="about">Acta pharmaceutica Sinica. B</div> <div itemprop="author">Tan J,Liu T,Fan W,Wei J,Zhu B,Liu Y,Liu L,Zhang X,Chen S,Lin H,Zhang Y,Li J</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Wed Feb 01 00:00:00 EST 2023</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/36793322"> <div itemprop="name">Oxygen-carrying nanoplatform to reprogram tumor immunosuppressive microenvironment and enhance photothermal-immunotherapy.</div> </a> <div itemprop="about">Materials today. Bio</div> <div itemprop="author">Huang J,Leng X,Jiang T,Xu L,Zheng J,Fang M,Wang J,Wang Z,Zhang L</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Sat Apr 01 00:00:00 EDT 2023</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/36980752"> <div itemprop="name">Non-Oncogene Addiction of <i>KRAS</i>-Mutant Cancers to IL-1β via Versican and Mononuclear IKKβ.</div> </a> <div itemprop="about">Cancers</div> <div itemprop="author">Spella M,Ntaliarda G,Skiadas G,Lamort AS,Vreka M,Marazioti A,Lilis I,Bouloukou E,Giotopoulou GA,Pepe MAA,Weiss SAI,Petrera A,Hauck SM,Koch I,Lindner M,Hatz RA,Behr J,Arendt KAM,Giopanou I,Brunn D,Savai R,Jenne DE,de Château M,Yull FE,Blackwell TS,Stathopoulos GT</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Mon Mar 20 00:00:00 EDT 2023</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/36114279"> <div itemprop="name">Metabolic improvement and liver regeneration by inhibiting CXXC5 function for non-alcoholic steatohepatitis treatment.</div> </a> <div itemprop="about">Experimental & molecular medicine</div> <div itemprop="author">Seo SH,Kim E,Yoon M,Lee SH,Park BH,Choi KY</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Thu Sep 01 00:00:00 EDT 2022</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/35058428"> <div itemprop="name">Macrophages in epididymal adipose tissue secrete osteopontin to regulate bone homeostasis.</div> </a> <div itemprop="about">Nature communications</div> <div itemprop="author">Dai B,Xu J,Li X,Huang L,Hopkins C,Wang H,Yao H,Mi J,Zheng L,Wang J,Tong W,Chow DH,Li Y,He X,Hu P,Chen Z,Zu H,Li Y,Yao Y,Jiang Q,Qin L</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Thu Jan 20 00:00:00 EST 2022</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/35365657"> <div itemprop="name">PI3Kγ stimulates a high molecular weight form of myosin light chain kinase to promote myeloid cell adhesion and tumor inflammation.</div> </a> <div itemprop="about">Nature communications</div> <div itemprop="author">Schmid MC,Kang SW,Chen H,Paradise M,Ghebremedhin A,Kaneda MM,Chin SM,Do A,Watterson DM,Varner JA</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Fri Apr 01 00:00:00 EDT 2022</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/35192633"> <div itemprop="name">Neutrophil-dendritic cell interaction plays an important role in live attenuated Leishmania vaccine induced immunity.</div> </a> <div itemprop="about">PLoS neglected tropical diseases</div> <div itemprop="author">Bhattacharya P,Ismail N,Saxena A,Gannavaram S,Dey R,Oljuskin T,Akue A,Takeda K,Yu J,Karmakar S,Dagur PK,McCoy JP,Nakhasi HL</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Tue Feb 01 00:00:00 EST 2022</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/36358310"> <div itemprop="name">TIM3 Expression in Anaplastic-Thyroid-Cancer-Infiltrating Macrophages: An Emerging Immunotherapeutic Target.</div> </a> <div itemprop="about">Biology</div> <div itemprop="author">Palacios LM,Peyret V,Viano ME,Geysels RC,Chocobar YA,Volpini X,Pellizas CG,Nicola JP,Motran CC,Rodriguez-Galan MC,Fozzatti L</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Thu Nov 03 00:00:00 EDT 2022</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/36703732"> <div itemprop="name">Comparative analysis of thoracic and abdominal aortic aneurysms across the segment and species at the single-cell level.</div> </a> <div itemprop="about">Frontiers in pharmacology</div> <div itemprop="author">Wu H,Xie C,Wang R,Cheng J,Xu Q,Zhao H</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Thu Feb 02 00:00:00 EST 2023</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/35943203"> <div itemprop="name">Microglial angiotensin type 2 receptors mediate sex-specific expression of inflammatory cytokines independently of circulating estrogen.</div> </a> <div itemprop="about">Glia</div> <div itemprop="author">Garrido-Gil P,Pedrosa MA,Garcia-Garrote M,Pequeño-Valtierra A,Rodríguez-Castro J,García-Souto D,Rodríguez-Pérez AI,Labandeira-Garcia JL</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Thu Dec 01 00:00:00 EST 2022</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/35487911"> <div itemprop="name">Regulation of chromatin accessibility by the histone chaperone CAF-1 sustains lineage fidelity.</div> </a> <div itemprop="about">Nature communications</div> <div itemprop="author">Franklin R,Guo Y,He S,Chen M,Ji F,Zhou X,Frankhouser D,Do BT,Chiem C,Jang M,Blanco MA,Vander Heiden MG,Rockne RC,Ninova M,Sykes DB,Hochedlinger K,Lu R,Sadreyev RI,Murn J,Volk A,Cheloufi S</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Fri Apr 29 00:00:00 EDT 2022</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/35386350"> <div itemprop="name">Biocompatible reduced graphene oxide stimulated BMSCs induce acceleration of bone remodeling and orthodontic tooth movement through promotion on osteoclastogenesis and angiogenesis.</div> </a> <div itemprop="about">Bioactive materials</div> <div itemprop="author">Jiao D,Wang J,Yu W,Zhang K,Zhang N,Cao L,Jiang X,Bai Y</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Thu Sep 01 00:00:00 EDT 2022</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33388094"> <div itemprop="name">Induction of alarmin S100A8/A9 mediates activation of aberrant neutrophils in the pathogenesis of COVID-19.</div> </a> <div itemprop="about">Cell host & microbe</div> <div itemprop="author">Guo Q,Zhao Y,Li J,Liu J,Yang X,Guo X,Kuang M,Xia H,Zhang Z,Cao L,Luo Y,Bao L,Wang X,Wei X,Deng W,Wang N,Chen L,Chen J,Zhu H,Gao R,Qin C,Wang X,You F</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Wed Feb 10 00:00:00 EST 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33300142"> <div itemprop="name">Mice with a specific deficiency of Pfkfb3 in myeloid cells are protected from hypoxia-induced pulmonary hypertension.</div> </a> <div itemprop="about">British journal of pharmacology</div> <div itemprop="author">Wang L,Zhang X,Cao Y,Ma Q,Mao X,Xu J,Yang Q,Zhou Y,Lucas R,Fulton DJ,Su Y,Barman SA,Hong M,Liu Z,Huo Y</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Mon Mar 01 00:00:00 EST 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33296111"> <div itemprop="name">The effects of postmortem delay on mouse and human microglia gene expression.</div> </a> <div itemprop="about">Glia</div> <div itemprop="author">Heng Y,Dubbelaar ML,Marie SKN,Boddeke EWGM,Eggen BJL</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Thu Apr 01 00:00:00 EDT 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33068332"> <div itemprop="name">Intrinsic DNA damage repair deficiency results in progressive microglia loss and replacement.</div> </a> <div itemprop="about">Glia</div> <div itemprop="author">Zhang X,Heng Y,Kooistra SM,van Weering HRJ,Brummer ML,Gerrits E,Wesseling EM,Brouwer N,Nijboer TW,Dubbelaar ML,Boddeke EWGM,Eggen BJL</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Mon Mar 01 00:00:00 EST 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/34092215"> <div itemprop="name">CD36 deficiency ameliorates drug-induced acute liver injury in mice.</div> </a> <div itemprop="about">Molecular medicine (Cambridge, Mass.)</div> <div itemprop="author">Zhang C,Shi X,Su Z,Hu C,Mu X,Pan J,Li M,Teng F,Ling T,Zhao T,Xu C,Ji G,You Q</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Sun Jun 06 00:00:00 EDT 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/34176822"> <div itemprop="name">Advanced maternal age induces fetal growth restriction through decreased placental inflammatory cytokine expression and immune cell accumulation in mice.</div> </a> <div itemprop="about">The Journal of reproduction and development</div> <div itemprop="author">Hirata Y,Katsukura Y,Henmi Y,Ozawa R,Shimazaki S,Kurosawa A,Torii Y,Takahashi H,Iwata H,Kuwayama T,Shirasuna K</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Fri Aug 27 00:00:00 EDT 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33830083"> <div itemprop="name">Brd4 modulates diet-induced obesity via PPARγ-dependent Gdf3 expression in adipose tissue macrophages.</div> </a> <div itemprop="about">JCI insight</div> <div itemprop="author">Hu X,Dong X,Li G,Chen Y,Chen J,He X,Sun H,Kim DH,Kemper JK,Chen LF</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Thu Apr 08 00:00:00 EDT 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/34831405"> <div itemprop="name">Polarization of Type 1 Macrophages Is Associated with the Severity of Viral Encephalitis Caused by Japanese Encephalitis Virus and Dengue Virus.</div> </a> <div itemprop="about">Cells</div> <div itemprop="author">Jhan MK,Chen CL,Shen TJ,Tseng PC,Wang YT,Satria RD,Yu CY,Lin CF</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Mon Nov 15 00:00:00 EST 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/34252585"> <div itemprop="name">Pancreatic Cancer Chemotherapy Is Potentiated by Induction of Tertiary Lymphoid Structures in Mice.</div> </a> <div itemprop="about">Cellular and molecular gastroenterology and hepatology</div> <div itemprop="author">Delvecchio FR,Fincham REA,Spear S,Clear A,Roy-Luzarraga M,Balkwill FR,Gribben JG,Bombardieri M,Hodivala-Dilke K,Capasso M,Kocher HM</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Mon Mar 28 00:00:00 EDT 2022</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/34289451"> <div itemprop="name">Myeloid DJ-1 deficiency protects acetaminophen-induced acute liver injury through decreasing inflammatory response.</div> </a> <div itemprop="about">Aging</div> <div itemprop="author">Wang B,Li J,Jiao J,Xu M,Luo Y,Wang F,Xia Q,Gao Y,Feng Y,Kong X,Sun X</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Wed Jul 21 00:00:00 EDT 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33758188"> <div itemprop="name">Mutant ASXL1 induces age-related expansion of phenotypic hematopoietic stem cells through activation of Akt/mTOR pathway.</div> </a> <div itemprop="about">Nature communications</div> <div itemprop="author">Fujino T,Goyama S,Sugiura Y,Inoue D,Asada S,Yamasaki S,Matsumoto A,Yamaguchi K,Isobe Y,Tsuchiya A,Shikata S,Sato N,Morinaga H,Fukuyama T,Tanaka Y,Fukushima T,Takeda R,Yamamoto K,Honda H,Nishimura EK,Furukawa Y,Shibata T,Abdel-Wahab O,Suematsu M,Kitamura T</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Tue Mar 23 00:00:00 EDT 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33786458"> <div itemprop="name"><i>In vitro</i> and <i>ex vivo</i> evaluation of tumor-derived exosome-induced dendritic cell dysfunction in mouse.</div> </a> <div itemprop="about">STAR protocols</div> <div itemprop="author">Zeng W,Yin X,Jiang Y,Jin L,Liang W</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Fri Mar 19 00:00:00 EDT 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/34137511"> <div itemprop="name">Platelet-Like Fusogenic Liposome-Mediated Targeting Delivery of miR-21 Improves Myocardial Remodeling by Reprogramming Macrophages Post Myocardial Ischemia-Reperfusion Injury.</div> </a> <div itemprop="about">Advanced science (Weinheim, Baden-Wurttemberg, Germany)</div> <div itemprop="author">Tan H,Song Y,Chen J,Zhang N,Wang Q,Li Q,Gao J,Yang H,Dong Z,Weng X,Wang Z,Sun D,Yakufu W,Pang Z,Huang Z,Ge J</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Sun Aug 01 00:00:00 EDT 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/34103524"> <div itemprop="name">Synergistic immunotherapy of glioblastoma by dual targeting of IL-6 and CD40.</div> </a> <div itemprop="about">Nature communications</div> <div itemprop="author">Yang F,He Z,Duan H,Zhang D,Li J,Yang H,Dorsey JF,Zou W,Nabavizadeh SA,Bagley SJ,Abdullah K,Brem S,Zhang L,Xu X,Byrne KT,Vonderheide RH,Gong Y,Fan Y</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Tue Jun 08 00:00:00 EDT 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33535605"> <div itemprop="name">Mechanical Stress Induce PG-E2 in Murine Synovial Fibroblasts Originating from the Temporomandibular Joint.</div> </a> <div itemprop="about">Cells</div> <div itemprop="author">Nazet U,Feulner L,Muschter D,Neubert P,Schatz V,Grässel S,Jantsch J,Proff P,Schröder A,Kirschneck C</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Mon Feb 01 00:00:00 EST 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/34393802"> <div itemprop="name">Electronic Cigarette Exposure Enhances Lung Inflammatory and Fibrotic Responses in COPD Mice.</div> </a> <div itemprop="about">Frontiers in pharmacology</div> <div itemprop="author">Han H,Peng G,Meister M,Yao H,Yang JJ,Zou MH,Liu ZR,Ji X</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Sat Apr 02 00:00:00 EDT 2022</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33548597"> <div itemprop="name">STING Activated Tumor-Intrinsic Type I Interferon Signaling Promotes CXCR3 Dependent Antitumor Immunity in Pancreatic Cancer.</div> </a> <div itemprop="about">Cellular and molecular gastroenterology and hepatology</div> <div itemprop="author">Vonderhaar EP,Barnekow NS,McAllister D,McOlash L,Eid MA,Riese MJ,Tarakanova VL,Johnson BD,Dwinell MB</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Mon Jan 24 00:00:00 EST 2022</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33991461"> <div itemprop="name">Prevention of non-alcoholic steatohepatitis by long-term exercise via the induction of phenotypic changes in Kupffer cells of hyperphagic obese mice.</div> </a> <div itemprop="about">Physiological reports</div> <div itemprop="author">Miura I,Komine S,Okada K,Wada S,Warabi E,Uchida F,Oh S,Suzuki H,Mizokami Y,Shoda J</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Sat May 01 00:00:00 EDT 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/34001904"> <div itemprop="name">Genetic fate-mapping reveals surface accumulation but not deep organ invasion of pleural and peritoneal cavity macrophages following injury.</div> </a> <div itemprop="about">Nature communications</div> <div itemprop="author">Jin H,Liu K,Tang J,Huang X,Wang H,Zhang Q,Zhu H,Li Y,Pu W,Zhao H,He L,Li Y,Zhang S,Zhang Z,Zhao Y,Qin Y,Pflanz S,Kasmi KEI,Zhang W,Liu Z,Ginhoux F,Ji Y,He B,Wang L,Zhou B</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Mon May 17 00:00:00 EDT 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/34305940"> <div itemprop="name">Desiccation Induced Conjunctival Monocyte Recruitment and Activation - Implications for Keratoconjunctivitis.</div> </a> <div itemprop="about">Frontiers in immunology</div> <div itemprop="author">Alam J,de Paiva CS,Pflugfelder SC</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Fri Dec 10 00:00:00 EST 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33789113"> <div itemprop="name">Macrophages in SHH subgroup medulloblastoma display dynamic heterogeneity that varies with treatment modality.</div> </a> <div itemprop="about">Cell reports</div> <div itemprop="author">Dang MT,Gonzalez MV,Gaonkar KS,Rathi KS,Young P,Arif S,Zhai L,Alam Z,Devalaraja S,To TKJ,Folkert IW,Raman P,Rokita JL,Martinez D,Taroni JN,Shapiro JA,Greene CS,Savonen C,Mafra F,Hakonarson H,Curran T,Haldar M</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Tue Mar 30 00:00:00 EDT 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/34086785"> <div itemprop="name">Inflammation-induced alterations in maternal-fetal Heme Oxygenase (HO) are associated with sustained innate immune cell dysregulation in mouse offspring.</div> </a> <div itemprop="about">PloS one</div> <div itemprop="author">Ozen M,Zhao H,Kalish F,Yang Y,Jantzie LL,Wong RJ,Stevenson DK</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Wed Nov 17 00:00:00 EST 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/34712222"> <div itemprop="name">A Population of M2 Macrophages Associated With Bone Formation.</div> </a> <div itemprop="about">Frontiers in immunology</div> <div itemprop="author">Olmsted-Davis E,Mejia J,Salisbury E,Gugala Z,Davis AR</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Mon Dec 13 00:00:00 EST 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33537102"> <div itemprop="name">Abraxane-induced bone marrow CD11b<sup>+</sup> myeloid cell depletion in tumor-bearing mice is visualized by μPET-CT with <sup>64</sup>Cu-labeled anti-CD11b and prevented by anti-CSF-1.</div> </a> <div itemprop="about">Theranostics</div> <div itemprop="author">Cao Q,Huang Q,Wang YA,Li C</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Fri Jul 23 00:00:00 EDT 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/34142101"> <div itemprop="name">Protocol for single-cell ATAC sequencing using combinatorial indexing in mouse lung adenocarcinoma.</div> </a> <div itemprop="about">STAR protocols</div> <div itemprop="author">Del Priore I,Ma S,Strecker J,Jacks T,LaFave LM,Buenrostro JD</div> <div itemprop="description">15-0112-82 was used in Flow Cytometry to show that sciATAC-seq is a cost-effective, extensible strategy that permits flexibility in the experimental scale via multiplexed barcoding across samples or perturbations.</div> <div itemprodp="datePublished">Fri Jun 18 00:00:00 EDT 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33602234"> <div itemprop="name">Small-molecule antagonist of VLA-4 (GW559090) attenuated neuro-inflammation by targeting Th17 cell trafficking across the blood-retinal barrier in experimental autoimmune uveitis.</div> </a> <div itemprop="about">Journal of neuroinflammation</div> <div itemprop="author">Chen YH,Eskandarpour M,Zhang X,Galatowicz G,Greenwood J,Lightman S,Calder V</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Thu Feb 18 00:00:00 EST 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33740009"> <div itemprop="name">Roles of lung-recruited monocytes and pulmonary Vascular Endothelial Growth Factor (VEGF) in resolving Ventilator-Induced Lung Injury (VILI).</div> </a> <div itemprop="about">PloS one</div> <div itemprop="author">Lin CK,Huang TH,Yang CT,Shi CS</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Tue Oct 12 00:00:00 EDT 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33618716"> <div itemprop="name">Systemic administration of β-glucan induces immune training in microglia.</div> </a> <div itemprop="about">Journal of neuroinflammation</div> <div itemprop="author">Heng Y,Zhang X,Borggrewe M,van Weering HRJ,Brummer ML,Nijboer TW,Joosten LAB,Netea MG,Boddeke EWGM,Laman JD,Eggen BJL</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Mon Feb 22 00:00:00 EST 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/34138183"> <div itemprop="name">Dual-Wavelength Photosensitive Nano-in-Micro Scaffold Regulates Innate and Adaptive Immune Responses for Osteogenesis.</div> </a> <div itemprop="about">Nano-micro letters</div> <div itemprop="author">Zhao Q,Shi M,Yin C,Zhao Z,Zhang J,Wang J,Shen K,Zhang L,Tang H,Xiao Y,Zhang Y</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Sat Nov 21 00:00:00 EST 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/31996021"> <div itemprop="name">IgE Contributes to Atherosclerosis and Obesity by Affecting Macrophage Polarization, Macrophage Protein Network, and Foam Cell Formation.</div> </a> <div itemprop="about">Arteriosclerosis, thrombosis, and vascular biology</div> <div itemprop="author">Zhang X,Li J,Luo S,Wang M,Huang Q,Deng Z,de Febbo C,Daoui A,Liew PX,Sukhova GK,Metso J,Jauhiainen M,Shi GP,Guo J</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Sun Mar 01 00:00:00 EST 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/31392723"> <div itemprop="name">Modulation of the functions of myeloid-derived suppressor cells : a new strategy of hydrogen sulfide anti-cancer effects.</div> </a> <div itemprop="about">British journal of pharmacology</div> <div itemprop="author">De Cicco P,Ercolano G,Rubino V,Terrazzano G,Ruggiero G,Cirino G,Ianaro A</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Sat Feb 01 00:00:00 EST 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/31719643"> <div itemprop="name">Alpha-hemolysin of uropathogenic Escherichia coli induces GM-CSF-mediated acute kidney injury.</div> </a> <div itemprop="about">Mucosal immunology</div> <div itemprop="author">Wang C,Li Q,Lv J,Sun X,Cao Y,Yu K,Miao C,Zhang ZS,Yao Z,Wang Q</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Wed Jan 01 00:00:00 EST 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/32150307"> <div itemprop="name">Temporospatial distribution and transcriptional profile of retinal microglia in the oxygen-induced retinopathy mouse model.</div> </a> <div itemprop="about">Glia</div> <div itemprop="author">Boeck M,Thien A,Wolf J,Hagemeyer N,Laich Y,Yusuf D,Backofen R,Zhang P,Boneva S,Stahl A,Hilgendorf I,Agostini H,Prinz M,Wieghofer P,Schlunck G,Schlecht A,Lange C</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Tue Sep 01 00:00:00 EDT 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33311847"> <div itemprop="name">Characterization and regulation of osteoclast precursors following chronic <i>Porphyromonas gingivalis</i> infection.</div> </a> <div itemprop="about">Journal of leukocyte biology</div> <div itemprop="author">Zhao Y,Li Z,Su L,Ballesteros-Tato A,Katz J,Michalek SM,Feng X,Zhang P</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Thu Oct 01 00:00:00 EDT 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/32186775"> <div itemprop="name">Mouse bone marrow mesenchymal stem cells with distinct p53 statuses display differential characteristics.</div> </a> <div itemprop="about">Molecular medicine reports</div> <div itemprop="author">Wang B,Wang L,Mao J,Wen H,Xu L,Ren Y,Du H,Yang H</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Fri May 01 00:00:00 EDT 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/32258126"> <div itemprop="name">Effects of Hypertonic Saline and Hydroxyethyl Starch on Myeloid-Derived Suppressor Cells in Hemorrhagic Shock Mice under Secondary Bacterial Attack.</div> </a> <div itemprop="about">BioMed research international</div> <div itemprop="author">Jiang JK,Hong LJ,Lu YQ</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Wed Dec 16 00:00:00 EST 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/32382015"> <div itemprop="name">Irradiation induces cancer lung metastasis through activation of the cGAS-STING-CCL5 pathway in mesenchymal stromal cells.</div> </a> <div itemprop="about">Cell death & disease</div> <div itemprop="author">Zheng Z,Jia S,Shao C,Shi Y</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Thu May 07 00:00:00 EDT 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33250891"> <div itemprop="name">Therapeutic Role of Inducible Nitric Oxide Synthase Expressing Myeloid-Derived Suppressor Cells in Acetaminophen-Induced Murine Liver Failure.</div> </a> <div itemprop="about">Frontiers in immunology</div> <div itemprop="author">Hsu CY,Lin YC,Chang LY,Huang SK,Huang CH,Yang CK,Huang CT,Lin CY</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Tue Jun 15 00:00:00 EDT 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33335790"> <div itemprop="name">Long Non-Coding RNA Hotairm1 Promotes S100A9 Support of MDSC Expansion during Sepsis.</div> </a> <div itemprop="about">Journal of clinical & cellular immunology</div> <div itemprop="author">Alkhateeb T,Bah I,Kumbhare A,Youssef D,Yao ZQ,McCall CE,Gazzar ME</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Sat Aug 13 00:00:00 EDT 2022</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/32943626"> <div itemprop="name">The lysophospholipase D enzyme Gdpd3 is required to maintain chronic myelogenous leukaemia stem cells.</div> </a> <div itemprop="about">Nature communications</div> <div itemprop="author">Naka K,Ochiai R,Matsubara E,Kondo C,Yang KM,Hoshii T,Araki M,Araki K,Sotomaru Y,Sasaki K,Mitani K,Kim DW,Ooshima A,Kim SJ</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Thu Sep 17 00:00:00 EDT 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33233625"> <div itemprop="name">Exploring the Role of Osteosarcoma-Derived Extracellular Vesicles in Pre-Metastatic Niche Formation and Metastasis in the 143-B Xenograft Mouse Osteosarcoma Model.</div> </a> <div itemprop="about">Cancers</div> <div itemprop="author">Mazumdar A,Urdinez J,Boro A,Arlt MJE,Egli FE,Niederöst B,Jaeger PK,Moschini G,Muff R,Fuchs B,Snedeker JG,Gvozdenovic A</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Fri Nov 20 00:00:00 EST 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/32431707"> <div itemprop="name">Lipin-1 Contributes to IL-4 Mediated Macrophage Polarization.</div> </a> <div itemprop="about">Frontiers in immunology</div> <div itemprop="author">Chandran S,Schilke RM,Blackburn CMR,Yurochko A,Mirza R,Scott RS,Finck BN,Woolard MD</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Mon Mar 29 00:00:00 EDT 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/32346042"> <div itemprop="name">Ly6c<sup>Lo</sup> non-classical monocytes promote resolution of rhesus rotavirus-mediated perinatal hepatic inflammation.</div> </a> <div itemprop="about">Scientific reports</div> <div itemprop="author">Alkhani A,Levy CS,Tsui M,Rosenberg KA,Polovina K,Mattis AN,Mack M,Van Dyken S,Wang BM,Maher JJ,Nijagal A</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Tue Apr 28 00:00:00 EDT 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/32731354"> <div itemprop="name">Stromal CCL2 Signaling Promotes Mammary Tumor Fibrosis through Recruitment of Myeloid-Lineage Cells.</div> </a> <div itemprop="about">Cancers</div> <div itemprop="author">Kuziel G,Thompson V,D'Amato JV,Arendt LM</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Tue Jul 28 00:00:00 EDT 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/32938973"> <div itemprop="name">The immune response after noise damage in the cochlea is characterized by a heterogeneous mix of adaptive and innate immune cells.</div> </a> <div itemprop="about">Scientific reports</div> <div itemprop="author">Rai V,Wood MB,Feng H,Schabla NM,Tu S,Zuo J</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Wed Sep 16 00:00:00 EDT 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33077427"> <div itemprop="name">Macrophage-Associated Lipin-1 Promotes β-Oxidation in Response to Proresolving Stimuli.</div> </a> <div itemprop="about">ImmunoHorizons</div> <div itemprop="author">Schilke RM,Blackburn CMR,Rao S,Krzywanski DM,Finck BN,Woolard MD</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Mon Oct 19 00:00:00 EDT 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33224133"> <div itemprop="name">TNFAIP3 Plays a Role in Aging of the Hematopoietic System.</div> </a> <div itemprop="about">Frontiers in immunology</div> <div itemprop="author">Smith MA,Culver-Cochran AE,Adelman ER,Rhyasen GW,Ma A,Figueroa ME,Starczynowski DT</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Wed Apr 28 00:00:00 EDT 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33224133"> <div itemprop="name">TNFAIP3 Plays a Role in Aging of the Hematopoietic System.</div> </a> <div itemprop="about">Frontiers in immunology</div> <div itemprop="author">Smith MA,Culver-Cochran AE,Adelman ER,Rhyasen GW,Ma A,Figueroa ME,Starczynowski DT</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Wed Apr 28 00:00:00 EDT 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33263277"> <div itemprop="name">Analysis of the immune response to sciatic nerve injury identifies efferocytosis as a key mechanism of nerve debridement.</div> </a> <div itemprop="about">eLife</div> <div itemprop="author">Kalinski AL,Yoon C,Huffman LD,Duncker PC,Kohen R,Passino R,Hafner H,Johnson C,Kawaguchi R,Carbajal KS,Jara JS,Hollis E,Geschwind DH,Segal BM,Giger RJ</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Wed Dec 02 00:00:00 EST 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33268774"> <div itemprop="name">CD103<sup>+</sup> cDC1 and endogenous CD8<sup>+</sup> T cells are necessary for improved CD40L-overexpressing CAR T cell antitumor function.</div> </a> <div itemprop="about">Nature communications</div> <div itemprop="author">Kuhn NF,Lopez AV,Li X,Cai W,Daniyan AF,Brentjens RJ</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Wed Dec 02 00:00:00 EST 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33317212"> <div itemprop="name">Authentication of Primary Murine Cell Lines by a Microfluidics-Based Lab-On-Chip System.</div> </a> <div itemprop="about">Biomedicines</div> <div itemprop="author">Hong Y,Singh N,Bamopoulos S,Gjerga E,Schmalbrock LK,Balabanian K,Schick M,Keller U,Wirth M</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Wed Dec 09 00:00:00 EST 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33257647"> <div itemprop="name">The armed oncolytic adenovirus ZD55-IL-24 eradicates melanoma by turning the tumor cells from the self-state into the nonself-state besides direct killing.</div> </a> <div itemprop="about">Cell death & disease</div> <div itemprop="author">Hu HJ,Liang X,Li HL,Du CM,Hao JL,Wang HY,Gu JF,Ni AM,Sun LY,Xiao J,Hu JQ,Yuan H,Dai YS,Jin XT,Zhang KJ,Liu XY</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Mon Nov 30 00:00:00 EST 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/32365632"> <div itemprop="name">L-Selectin/CD62L is a Key Driver of Non-Alcoholic Steatohepatitis in Mice and Men.</div> </a> <div itemprop="about">Cells</div> <div itemprop="author">Drescher HK,Schippers A,Rosenhain S,Gremse F,Bongiovanni L,Bruin A,Eswaran S,Gallage SU,Pfister D,Szydlowska M,Heikenwalder M,Weiskirchen S,Wagner N,Trautwein C,Weiskirchen R,Kroy DC</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Wed Apr 29 00:00:00 EDT 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/32814714"> <div itemprop="name">Ovarian granulosa cell tumor characterization identifies FOXL2 as an immunotherapeutic target.</div> </a> <div itemprop="about">JCI insight</div> <div itemprop="author">Pierini S,Tanyi JL,Simpkins F,George E,Uribe-Herranz M,Drapkin R,Burger R,Morgan MA,Facciabene A</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Thu Aug 20 00:00:00 EDT 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/32973765"> <div itemprop="name">Protein Tyrosine Phosphatase Non-Receptor Type 2 Function in Dendritic Cells Is Crucial to Maintain Tissue Tolerance.</div> </a> <div itemprop="about">Frontiers in immunology</div> <div itemprop="author">Hering L,Katkeviciute E,Schwarzfischer M,Busenhart P,Gottier C,Mrdjen D,Komuczki J,Wawrzyniak M,Lang S,Atrott K,Becher B,Rogler G,Scharl M,Spalinger MR</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Mon Apr 12 00:00:00 EDT 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/32855397"> <div itemprop="name">Senolytics prevent mt-DNA-induced inflammation and promote the survival of aged organs following transplantation.</div> </a> <div itemprop="about">Nature communications</div> <div itemprop="author">Iske J,Seyda M,Heinbokel T,Maenosono R,Minami K,Nian Y,Quante M,Falk CS,Azuma H,Martin F,Passos JF,Niemann CU,Tchkonia T,Kirkland JL,Elkhal A,Tullius SG</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Thu Aug 27 00:00:00 EDT 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33208556"> <div itemprop="name">Hyaluronan control of the primary vascular barrier during early mouse pregnancy is mediated by uterine NK cells.</div> </a> <div itemprop="about">JCI insight</div> <div itemprop="author">Hadas R,Gershon E,Cohen A,Atrakchi O,Lazar S,Golani O,Dassa B,Elbaz M,Cohen G,Eilam R,Dekel N,Neeman M</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Thu Nov 19 00:00:00 EST 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33232280"> <div itemprop="name">Loss of Atg7 causes chaotic nucleosome assembly of mouse bone marrow CD11b<sup>+</sup>Ly6G<sup>-</sup> myeloid cells.</div> </a> <div itemprop="about">Aging</div> <div itemprop="author">Fang Y,Gu Y,Li L,Zhu L,Qian J,Zhao C,Xu L,Wei W,Du Y,Yuan N,Zhang S,Yuan Y,Xu Y,Jiang C,Wang J</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Tue Nov 24 00:00:00 EST 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/32645949"> <div itemprop="name">Bivalent Inhibitor with Selectivity for Trimeric MMP-9 Amplifies Neutrophil Chemotaxis and Enables Functional Studies on MMP-9 Proteoforms.</div> </a> <div itemprop="about">Cells</div> <div itemprop="author">Nuti E,Rossello A,Cuffaro D,Camodeca C,Van Bael J,van der Maat D,Martens E,Fiten P,Pereira RVS,Ugarte-Berzal E,Gouwy M,Opdenakker G,Vandooren J</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Tue Jul 07 00:00:00 EDT 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33246491"> <div itemprop="name">Apoptotic bodies derived from mesenchymal stem cells promote cutaneous wound healing via regulating the functions of macrophages.</div> </a> <div itemprop="about">Stem cell research & therapy</div> <div itemprop="author">Liu J,Qiu X,Lv Y,Zheng C,Dong Y,Dou G,Zhu B,Liu A,Wang W,Zhou J,Liu S,Liu S,Gao B,Jin Y</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Fri Nov 27 00:00:00 EST 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/31947892"> <div itemprop="name">GDF3 Protects Mice against Sepsis-Induced Cardiac Dysfunction and Mortality by Suppression of Macrophage Pro-Inflammatory Phenotype.</div> </a> <div itemprop="about">Cells</div> <div itemprop="author">Wang L,Li Y,Wang X,Wang P,Essandoh K,Cui S,Huang W,Mu X,Liu Z,Wang Y,Peng T,Fan GC</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Fri Jan 03 00:00:00 EST 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/32021837"> <div itemprop="name">Differential Activation of Macrophages Based on Their Environment in Advanced Age.</div> </a> <div itemprop="about">Chonnam medical journal</div> <div itemprop="author">Lee DY,Lim JS,Cho KA</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Wed Jan 01 00:00:00 EST 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/32411498"> <div itemprop="name">G protein-coupled receptor 68 increases the number of B lymphocytes.</div> </a> <div itemprop="about">American journal of blood research</div> <div itemprop="author">He X,Feng S,Hawkins C,Lawley L,Fan W,Xu Y,Zha XM,Fang J</div> <div itemprop="description">15-0112 was used in Flow cytometry/Cell sorting to indicate that Gpr68 expression is upregulated in hematopoietic cells upon aging and during hematopoietic regeneration that ends up with increased number of B lymphocytes.</div> <div itemprodp="datePublished">Mon Sep 28 00:00:00 EDT 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33203971"> <div itemprop="name">Methamphetamine induces cardiomyopathy by Sigmar1 inhibition-dependent impairment of mitochondrial dynamics and function.</div> </a> <div itemprop="about">Communications biology</div> <div itemprop="author">Abdullah CS,Aishwarya R,Alam S,Morshed M,Remex NS,Nitu S,Kolluru GK,Traylor J,Miriyala S,Panchatcharam M,Hartman B,King J,Bhuiyan MAN,Chandran S,Woolard MD,Yu X,Goeders NE,Dominic P,Arnold CL,Stokes K,Kevil CG,Orr AW,Bhuiyan MS</div> <div itemprop="description">15-0112-82 was used in Flow Cytometry to show that Sigmar1 is a therapeutic target for methamphetamine-associated cardiomyopathy.</div> <div itemprodp="datePublished">Tue Nov 17 00:00:00 EST 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33584313"> <div itemprop="name">Loss of FGFR3 Delays Acute Myeloid Leukemogenesis by Programming Weakly Pathogenic CD117-Positive Leukemia Stem-Like Cells.</div> </a> <div itemprop="about">Frontiers in pharmacology</div> <div itemprop="author">Guo C,Ran Q,Sun C,Zhou T,Yang X,Zhang J,Pang S,Xiao Y</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Tue Feb 16 00:00:00 EST 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/30664762"> <div itemprop="name">Basophil-derived tumor necrosis factor can enhance survival in a sepsis model in mice.</div> </a> <div itemprop="about">Nature immunology</div> <div itemprop="author">Piliponsky AM,Shubin NJ,Lahiri AK,Truong P,Clauson M,Niino K,Tsuha AL,Nedospasov SA,Karasuyama H,Reber LL,Tsai M,Mukai K,Galli SJ</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Fri Feb 01 00:00:00 EST 2019</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/31182869"> <div itemprop="name">Central nervous system regeneration is driven by microglia necroptosis and repopulation.</div> </a> <div itemprop="about">Nature neuroscience</div> <div itemprop="author">Lloyd AF,Davies CL,Holloway RK,Labrak Y,Ireland G,Carradori D,Dillenburg A,Borger E,Soong D,Richardson JC,Kuhlmann T,Williams A,Pollard JW,des Rieux A,Priller J,Miron VE</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Mon Jul 01 00:00:00 EDT 2019</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/30338847"> <div itemprop="name">Seselin ameliorates inflammation via targeting Jak2 to suppress the proinflammatory phenotype of macrophages.</div> </a> <div itemprop="about">British journal of pharmacology</div> <div itemprop="author">Feng L,Sun Y,Song P,Xu L,Wu X,Wu X,Shen Y,Sun Y,Kong L,Wu X,Xu Q</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Tue Jan 01 00:00:00 EST 2019</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/31118047"> <div itemprop="name">Leptin produced by obesity-altered adipose stem cells promotes metastasis but not tumorigenesis of triple-negative breast cancer in orthotopic xenograft and patient-derived xenograft models.</div> </a> <div itemprop="about">Breast cancer research : BCR</div> <div itemprop="author">Sabol RA,Bowles AC,Côté A,Wise R,O'Donnell B,Matossian MD,Hossain FM,Burks HE,Del Valle L,Miele L,Collins-Burow BM,Burow ME,Bunnell BA</div> <div itemprop="description">15-0112 was used in Flow cytometry/Cell sorting to study the mechanisms by which obesity promotes tumour progression.</div> <div itemprodp="datePublished">Wed May 22 00:00:00 EDT 2019</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/30246247"> <div itemprop="name">Distinct Tie2 tyrosine phosphorylation sites dictate phenotypic switching in endothelial progenitor cells.</div> </a> <div itemprop="about">Journal of cellular physiology</div> <div itemprop="author">Siavashi V,Nassiri SM,Rahbarghazi R,Mohseni Z,Sharifi AM</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Wed May 01 00:00:00 EDT 2019</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/31354896"> <div itemprop="name">Antiallodynic Effects of Cannabinoid Receptor 2 (CB<sub>2</sub>R) Agonists on Retrovirus Infection-Induced Neuropathic Pain.</div> </a> <div itemprop="about">Pain research & management</div> <div itemprop="author">Sheng WS,Chauhan P,Hu S,Prasad S,Lokensgard JR</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Mon Dec 16 00:00:00 EST 2019</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/30998512"> <div itemprop="name">Antitumor and immunomodulatory effects of a novel multitarget inhibitor, CS2164, in mouse hepatocellular carcinoma models.</div> </a> <div itemprop="about">Anti-cancer drugs</div> <div itemprop="author">Zhou Y,Fu C,Kong Y,Pan D,Wang Y,Huang S,Li Z,Ning Z,Lu X,Shan S,Xin L</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Tue Oct 01 00:00:00 EDT 2019</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/30970257"> <div itemprop="name">TRIM9-Mediated Resolution of Neuroinflammation Confers Neuroprotection upon Ischemic Stroke in Mice.</div> </a> <div itemprop="about">Cell reports</div> <div itemprop="author">Zeng J,Wang Y,Luo Z,Chang LC,Yoo JS,Yan H,Choi Y,Xie X,Deverman BE,Gradinaru V,Gupton SL,Zlokovic BV,Zhao Z,Jung JU</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Tue Apr 09 00:00:00 EDT 2019</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/31519886"> <div itemprop="name">Ubiquitination of RIPK1 suppresses programmed cell death by regulating RIPK1 kinase activation during embryogenesis.</div> </a> <div itemprop="about">Nature communications</div> <div itemprop="author">Zhang X,Zhang H,Xu C,Li X,Li M,Wu X,Pu W,Zhou B,Wang H,Li D,Ding Q,Ying H,Wang H,Zhang H</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Fri Sep 13 00:00:00 EDT 2019</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/30971711"> <div itemprop="name">Neural anti-inflammatory action mediated by two types of acetylcholine receptors in the small intestine.</div> </a> <div itemprop="about">Scientific reports</div> <div itemprop="author">Kimura H,Imura YK,Tomiyasu H,Mihara T,Kaji N,Ohno K,Unno T,Tanahashi Y,Jan TR,Tsubone H,Ozaki H,Hori M</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Wed Apr 10 00:00:00 EDT 2019</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/31779710"> <div itemprop="name">MDM2 inhibitor APG-115 synergizes with PD-1 blockade through enhancing antitumor immunity in the tumor microenvironment.</div> </a> <div itemprop="about">Journal for immunotherapy of cancer</div> <div itemprop="author">Fang DD,Tang Q,Kong Y,Wang Q,Gu J,Fang X,Zou P,Rong T,Wang J,Yang D,Zhai Y</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Thu Nov 28 00:00:00 EST 2019</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/30711545"> <div itemprop="name">Muscularis Propria Macrophages Alter the Proportion of Nitrergic but Not Cholinergic Gastric Myenteric Neurons.</div> </a> <div itemprop="about">Cellular and molecular gastroenterology and hepatology</div> <div itemprop="author">Cipriani G,Terhaar ML,Eisenman ST,Ji S,Linden DR,Wright AM,Sha L,Ordog T,Szurszewski JH,Gibbons SJ,Farrugia G</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Tue Jun 04 00:00:00 EDT 2019</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/31481966"> <div itemprop="name">Tpl2 Protects Against Fulminant Hepatitis Through Mobilization of Myeloid-Derived Suppressor Cells.</div> </a> <div itemprop="about">Frontiers in immunology</div> <div itemprop="author">Xu J,Pei S,Wang Y,Liu J,Qian Y,Huang M,Zhang Y,Xiao Y</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Wed Oct 14 00:00:00 EDT 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/31787973"> <div itemprop="name">Exposure to Cigarette Smoke Augments Post-ischemic Brain Injury and Inflammation via Mobilization of Neutrophils and Monocytes.</div> </a> <div itemprop="about">Frontiers in immunology</div> <div itemprop="author">Li H,Li X,Gao S,Wang D,Gao X,Li Y,Wang X,Cui Z,Ma H,Liu Q,Li M</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Mon Sep 28 00:00:00 EDT 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/31528845"> <div itemprop="name">Knockdown of <i>Ant2</i> Reduces Adipocyte Hypoxia And Improves Insulin Resistance in Obesity.</div> </a> <div itemprop="about">Nature metabolism</div> <div itemprop="author">Seo JB,Riopel M,Cabrales P,Huh JY,Bandyopadhyay GK,Andreyev AY,Murphy AN,Beeman SC,Smith GI,Klein S,Lee YS,Olefsky JM</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Tue Jan 01 00:00:00 EST 2019</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/30796225"> <div itemprop="name">Inducing cancer indolence by targeting mitochondrial Complex I is potentiated by blocking macrophage-mediated adaptive responses.</div> </a> <div itemprop="about">Nature communications</div> <div itemprop="author">Kurelac I,Iommarini L,Vatrinet R,Amato LB,De Luise M,Leone G,Girolimetti G,Umesh Ganesh N,Bridgeman VL,Ombrato L,Columbaro M,Ragazzi M,Gibellini L,Sollazzo M,Feichtinger RG,Vidali S,Baldassarre M,Foriel S,Vidone M,Cossarizza A,Grifoni D,Kofler B,Malanchi I,Porcelli AM,Gasparre G</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Fri Feb 22 00:00:00 EST 2019</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/30893599"> <div itemprop="name">Nidogen-1 Contributes to the Interaction Network Involved in Pro-B Cell Retention in the Peri-sinusoidal Hematopoietic Stem Cell Niche.</div> </a> <div itemprop="about">Cell reports</div> <div itemprop="author">Balzano M,De Grandis M,Vu Manh TP,Chasson L,Bardin F,Farina A,Sergé A,Bidaut G,Charbord P,Hérault L,Bailly AL,Cartier-Michaud A,Boned A,Dalod M,Duprez E,Genever P,Coles M,Bajenoff M,Xerri L,Aurrand-Lions M,Schiff C,Mancini SJC</div> <div itemprop="description">15-0112 was used in Flow cytometry/Cell sorting to study pro-B cells in their support of stroll cells and their interaction network allowing their retention.</div> <div itemprodp="datePublished">Tue Mar 19 00:00:00 EDT 2019</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/30650358"> <div itemprop="name">N-Cadherin-Expressing Bone and Marrow Stromal Progenitor Cells Maintain Reserve Hematopoietic Stem Cells.</div> </a> <div itemprop="about">Cell reports</div> <div itemprop="author">Zhao M,Tao F,Venkatraman A,Li Z,Smith SE,Unruh J,Chen S,Ward C,Qian P,Perry JM,Marshall H,Wang J,He XC,Li L</div> <div itemprop="description">15-0112 was used in Flow cytometry/Cell sorting to report that N-cad+ cells were functional bone and marrow stromal progenitor cells, giving rise to osteoblasts, adipocytes, and chondrocytes both in vitro and in vivo.</div> <div itemprodp="datePublished">Tue Jan 15 00:00:00 EST 2019</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/30842412"> <div itemprop="name">Ufbp1 promotes plasma cell development and ER expansion by modulating distinct branches of UPR.</div> </a> <div itemprop="about">Nature communications</div> <div itemprop="author">Zhu H,Bhatt B,Sivaprakasam S,Cai Y,Liu S,Kodeboyina SK,Patel N,Savage NM,Sharma A,Kaufman RJ,Li H,Singh N</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Wed Mar 06 00:00:00 EST 2019</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/30700748"> <div itemprop="name">The nuclear variant of bone morphogenetic protein 2 (nBMP2) is expressed in macrophages and alters calcium response.</div> </a> <div itemprop="about">Scientific reports</div> <div itemprop="author">Tellez Freitas CM,Burrell HR,Valdoz JC,Hamblin GJ,Raymond CM,Cox TD,Johnson DK,Andersen JL,Weber KS,Bridgewater LC</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Wed Jan 30 00:00:00 EST 2019</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/30755607"> <div itemprop="name">Costimulation of type-2 innate lymphoid cells by GITR promotes effector function and ameliorates type 2 diabetes.</div> </a> <div itemprop="about">Nature communications</div> <div itemprop="author">Galle-Treger L,Sankaranarayanan I,Hurrell BP,Howard E,Lo R,Maazi H,Lewis G,Banie H,Epstein AL,Hu P,Rehan VK,Gilliland FD,Allayee H,Soroosh P,Sharpe AH,Akbari O</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Tue Feb 12 00:00:00 EST 2019</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/30510995"> <div itemprop="name">Toll-Like Receptor 7 Agonist-Induced Dermatitis Causes Severe Dextran Sulfate Sodium Colitis by Altering the Gut Microbiome and Immune Cells.</div> </a> <div itemprop="about">Cellular and molecular gastroenterology and hepatology</div> <div itemprop="author">Kiyohara H,Sujino T,Teratani T,Miyamoto K,Arai MM,Nomura E,Harada Y,Aoki R,Koda Y,Mikami Y,Mizuno S,Naganuma M,Hisamatsu T,Kanai T</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Mon Apr 29 00:00:00 EDT 2019</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/31780645"> <div itemprop="name">Inflammation induced by incomplete radiofrequency ablation accelerates tumor progression and hinders PD-1 immunotherapy.</div> </a> <div itemprop="about">Nature communications</div> <div itemprop="author">Shi L,Wang J,Ding N,Zhang Y,Zhu Y,Dong S,Wang X,Peng C,Zhou C,Zhou L,Li X,Shi H,Wu W,Long X,Wu C,Liao W</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Thu Nov 28 00:00:00 EST 2019</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/29670286"> <div itemprop="name">Pluripotency factors functionally premark cell-type-restricted enhancers in ES cells.</div> </a> <div itemprop="about">Nature</div> <div itemprop="author">Kim HS,Tan Y,Ma W,Merkurjev D,Destici E,Ma Q,Suter T,Ohgi K,Friedman M,Skowronska-Krawczyk D,Rosenfeld MG</div> <div itemprop="description">15-0112 was used in Immunocytochemistry-Immunofluorescence to examine the hierarchical and obligate premarking of cell-type-restricted enhancers in embryonic stem cells.</div> <div itemprodp="datePublished">Sun Apr 01 00:00:00 EDT 2018</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/30464343"> <div itemprop="name">Efferocytosis induces a novel SLC program to promote glucose uptake and lactate release.</div> </a> <div itemprop="about">Nature</div> <div itemprop="author">Morioka S,Perry JSA,Raymond MH,Medina CB,Zhu Y,Zhao L,Serbulea V,Onengut-Gumuscu S,Leitinger N,Kucenas S,Rathmell JC,Makowski L,Ravichandran KS</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Thu Nov 01 00:00:00 EDT 2018</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/29769727"> <div itemprop="name">Microbial signals drive pre-leukaemic myeloproliferation in a Tet2-deficient host.</div> </a> <div itemprop="about">Nature</div> <div itemprop="author">Meisel M,Hinterleitner R,Pacis A,Chen L,Earley ZM,Mayassi T,Pierre JF,Ernest JD,Galipeau HJ,Thuille N,Bouziat R,Buscarlet M,Ringus DL,Wang Y,Li Y,Dinh V,Kim SM,McDonald BD,Zurenski MA,Musch MW,Furtado GC,Lira SA,Baier G,Chang EB,Eren AM,Weber CR,Busque L,Godley LA,Verdú EF,Barreiro LB,Jabri B</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Tue May 01 00:00:00 EDT 2018</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/29695863"> <div itemprop="name">LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis.</div> </a> <div itemprop="about">Nature</div> <div itemprop="author">Peltzer N,Darding M,Montinaro A,Draber P,Draberova H,Kupka S,Rieser E,Fisher A,Hutchinson C,Taraborrelli L,Hartwig T,Lafont E,Haas TL,Shimizu Y,Böiers C,Sarr A,Rickard J,Alvarez-Diaz S,Ashworth MT,Beal A,Enver T,Bertin J,Kaiser W,Strasser A,Silke J,Bouillet P,Walczak H</div> <div itemprop="description">15-0112-82 was used in Flow cytometry/Cell sorting to demonstrate that both linear ubiquitin chain assembly complex components HOIP and HOIL-1, are required for embryogenesis by preventing cell death.</div> <div itemprodp="datePublished">Tue May 01 00:00:00 EDT 2018</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/29249358"> <div itemprop="name">Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells.</div> </a> <div itemprop="about">Cell</div> <div itemprop="author">Gaya M,Barral P,Burbage M,Aggarwal S,Montaner B,Warren Navia A,Aid M,Tsui C,Maldonado P,Nair U,Ghneim K,Fallon PG,Sekaly RP,Barouch DH,Shalek AK,Bruckbauer A,Strid J,Batista FD</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Thu Jan 25 00:00:00 EST 2018</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/29909986"> <div itemprop="name">Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis.</div> </a> <div itemprop="about">Cell</div> <div itemprop="author">Ziegler PK,Bollrath J,Pallangyo CK,Matsutani T,Canli Ö,De Oliveira T,Diamanti MA,Müller N,Gamrekelashvili J,Putoczki T,Horst D,Mankan AK,Öner MG,Müller S,Müller-Höcker J,Kirchner T,Slotta-Huspenina J,Taketo MM,Reinheckel T,Dröse S,Larner AC,Wels WS,Ernst M,Greten TF,Arkan MC,Korn T,Wirth D,Greten FR</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Thu Jun 28 00:00:00 EDT 2018</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/29343440"> <div itemprop="name">Chanzyme TRPM7 Mediates the Ca<sup>2+</sup> Influx Essential for Lipopolysaccharide-Induced Toll-Like Receptor 4 Endocytosis and Macrophage Activation.</div> </a> <div itemprop="about">Immunity</div> <div itemprop="author">Schappe MS,Szteyn K,Stremska ME,Mendu SK,Downs TK,Seegren PV,Mahoney MA,Dixit S,Krupa JK,Stipes EJ,Rogers JS,Adamson SE,Leitinger N,Desai BN</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Tue Jan 16 00:00:00 EST 2018</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/29452935"> <div itemprop="name">E3 Ligase VHL Promotes Group 2 Innate Lymphoid Cell Maturation and Function via Glycolysis Inhibition and Induction of Interleukin-33 Receptor.</div> </a> <div itemprop="about">Immunity</div> <div itemprop="author">Li Q,Li D,Zhang X,Wan Q,Zhang W,Zheng M,Zou L,Elly C,Lee JH,Liu YC</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Tue Feb 20 00:00:00 EST 2018</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/29802020"> <div itemprop="name">Autoimmune Th17 Cells Induced Synovial Stromal and Innate Lymphoid Cell Secretion of the Cytokine GM-CSF to Initiate and Augment Autoimmune Arthritis.</div> </a> <div itemprop="about">Immunity</div> <div itemprop="author">Hirota K,Hashimoto M,Ito Y,Matsuura M,Ito H,Tanaka M,Watanabe H,Kondoh G,Tanaka A,Yasuda K,Kopf M,Potocnik AJ,Stockinger B,Sakaguchi N,Sakaguchi S</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Tue Jun 19 00:00:00 EDT 2018</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/29528335"> <div itemprop="name">Insulin resistance causes inflammation in adipose tissue.</div> </a> <div itemprop="about">The Journal of clinical investigation</div> <div itemprop="author">Shimobayashi M,Albert V,Woelnerhanssen B,Frei IC,Weissenberger D,Meyer-Gerspach AC,Clement N,Moes S,Colombi M,Meier JA,Swierczynska MM,Jenö P,Beglinger C,Peterli R,Hall MN</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Mon Apr 02 00:00:00 EDT 2018</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/29708507"> <div itemprop="name">Granulocyte-CSF links destructive inflammation and comorbidities in obstructive lung disease.</div> </a> <div itemprop="about">The Journal of clinical investigation</div> <div itemprop="author">Tsantikos E,Lau M,Castelino CM,Maxwell MJ,Passey SL,Hansen MJ,McGregor NE,Sims NA,Steinfort DP,Irving LB,Anderson GP,Hibbs ML</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Fri Jun 01 00:00:00 EDT 2018</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/29180395"> <div itemprop="name">Tamm-Horsfall Protein Regulates Mononuclear Phagocytes in the Kidney.</div> </a> <div itemprop="about">Journal of the American Society of Nephrology : JASN</div> <div itemprop="author">Micanovic R,Khan S,Janosevic D,Lee ME,Hato T,Srour EF,Winfree S,Ghosh J,Tong Y,Rice SE,Dagher PC,Wu XR,El-Achkar TM</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Thu Mar 01 00:00:00 EST 2018</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/29891135"> <div itemprop="name">11 Beta-hydroxysteroid dehydrogenase type 1 regulates synovitis, joint destruction, and systemic bone loss in chronic polyarthritis.</div> </a> <div itemprop="about">Journal of autoimmunity</div> <div itemprop="author">Hardy RS,Fenton C,Croft AP,Naylor AJ,Begum R,Desanti G,Buckley CD,Lavery G,Cooper MS,Raza K</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Wed Aug 01 00:00:00 EDT 2018</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/29666270"> <div itemprop="name">MK2 contributes to tumor progression by promoting M2 macrophage polarization and tumor angiogenesis.</div> </a> <div itemprop="about">Proceedings of the National Academy of Sciences of the United States of America</div> <div itemprop="author">Suarez-Lopez L,Sriram G,Kong YW,Morandell S,Merrick KA,Hernandez Y,Haigis KM,Yaffe MB</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Tue May 01 00:00:00 EDT 2018</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/29662483"> <div itemprop="name">Long Non-Coding RNA HOXA Transcript Antisense RNA Myeloid-Specific 1-HOXA1 Axis Downregulates the Immunosuppressive Activity of Myeloid-Derived Suppressor Cells in Lung Cancer.</div> </a> <div itemprop="about">Frontiers in immunology</div> <div itemprop="author">Tian X,Ma J,Wang T,Tian J,Zhang Y,Mao L,Xu H,Wang S</div> <div itemprop="description">15-0112 was used in Flow cytometry/Cell sorting to conclude that HOXA transcript antisense RNA myeloid-specific 1 (HOTAIRM1) downregulates the immunosuppressive function of myeloid-derived suppressor cells by targeting HOXA1, providing a potential therapeutic target in lung cancer.</div> <div itemprodp="datePublished">Mon Jun 24 00:00:00 EDT 2019</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/30306644"> <div itemprop="name">VISTA expression by microglia decreases during inflammation and is differentially regulated in CNS diseases.</div> </a> <div itemprop="about">Glia</div> <div itemprop="author">Borggrewe M,Grit C,Den Dunnen WFA,Burm SM,Bajramovic JJ,Noelle RJ,Eggen BJL,Laman JD</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Sat Dec 01 00:00:00 EST 2018</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/28266709"> <div itemprop="name">Bone loss in C57BL/6J-OlaHsd mice, a substrain of C57BL/6J carrying mutated alpha-synuclein and multimerin-1 genes.</div> </a> <div itemprop="about">Journal of cellular physiology</div> <div itemprop="author">Liron T,Raphael B,Hiram-Bab S,Bab IA,Gabet Y</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Mon Jan 01 00:00:00 EST 2018</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/29206332"> <div itemprop="name">Inactivation of mTORC1 Signaling in Osterix-Expressing Cells Impairs B-cell Differentiation.</div> </a> <div itemprop="about">Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research</div> <div itemprop="author">Wang Y,Xiao M,Tao C,Chen J,Wang Z,Yang J,Chen Z,Zou Z,Liu A,Cai D,Jiang Y,Ding C,Li M,Bai X</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Sun Apr 01 00:00:00 EDT 2018</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/28801344"> <div itemprop="name">Frontline Science: Macrophage-derived exosomes promote neutrophil necroptosis following hemorrhagic shock.</div> </a> <div itemprop="about">Journal of leukocyte biology</div> <div itemprop="author">Jiao Y,Li Z,Loughran PA,Fan EK,Scott MJ,Li Y,Billiar TR,Wilson MA,Shi X,Fan J</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Thu Feb 01 00:00:00 EST 2018</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/29858266"> <div itemprop="name">The Outcome of the <i>Cryptococcus neoformans-</i>Macrophage Interaction Depends on Phagolysosomal Membrane Integrity.</div> </a> <div itemprop="about">Journal of immunology (Baltimore, Md. : 1950)</div> <div itemprop="author">De Leon-Rodriguez CM,Rossi DCP,Fu MS,Dragotakes Q,Coelho C,Guerrero Ros I,Caballero B,Nolan SJ,Casadevall A</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Sun Jul 15 00:00:00 EDT 2018</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/29409022"> <div itemprop="name">Dysregulation of Kupffer Cells/Macrophages and Natural Killer T Cells in Steatohepatitis in LXRα Knockout Male Mice.</div> </a> <div itemprop="about">Endocrinology</div> <div itemprop="author">Endo-Umeda K,Nakashima H,Umeda N,Seki S,Makishima M</div> <div itemprop="description"></div> <div itemprodp="datePublished">Thu Mar 01 00:00:00 EST 2018</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/29543508"> <div itemprop="name">Primary cilia disruption differentially affects the infiltrating and resident macrophage compartment in the liver.</div> </a> <div itemprop="about">American journal of physiology. Gastrointestinal and liver physiology</div> <div itemprop="author">Zimmerman KA,Song CJ,Gonzalez-Mize N,Li Z,Yoder BK</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Fri Jun 01 00:00:00 EDT 2018</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/29138852"> <div itemprop="name">Anti‑IL‑39 (IL‑23p19/Ebi3) polyclonal antibodies ameliorate autoimmune symptoms in lupus‑like mice.</div> </a> <div itemprop="about">Molecular medicine reports</div> <div itemprop="author">Wang X,Zhang Y,Wang Z,Liu X,Zhu G,Han G,Chen G,Hou C,Wang T,Shen B,Li Y,Xiao H,Ma N,Wang R</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Mon Jan 01 00:00:00 EST 2018</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/29115623"> <div itemprop="name">A novel method to isolate mesenchymal stem cells from mouse umbilical cord.</div> </a> <div itemprop="about">Molecular medicine reports</div> <div itemprop="author">Zhang B,Zhang J,Shi H,Mao F,Wang J,Yan Y,Zhang X,Qian H,Xu W</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Mon Jan 01 00:00:00 EST 2018</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/30542473"> <div itemprop="name">Simultaneous isolation of mesenchymal stem cells and endothelial progenitor cells derived from murine bone marrow.</div> </a> <div itemprop="about">Experimental and therapeutic medicine</div> <div itemprop="author">Wang X,Zhao Z,Zhang H,Hou J,Feng W,Zhang M,Guo J,Xia J,Ge Q,Chen X,Wu X</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Sat Dec 01 00:00:00 EST 2018</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/29727682"> <div itemprop="name">Retinoid-Sensitive Epigenetic Regulation of the Hoxb Cluster Maintains Normal Hematopoiesis and Inhibits Leukemogenesis.</div> </a> <div itemprop="about">Cell stem cell</div> <div itemprop="author">Qian P,De Kumar B,He XC,Nolte C,Gogol M,Ahn Y,Chen S,Li Z,Xu H,Perry JM,Hu D,Tao F,Zhao M,Han Y,Hall K,Peak A,Paulson A,Zhao C,Venkatraman A,Box A,Perera A,Haug JS,Parmely T,Li H,Krumlauf R,Li L</div> <div itemprop="description">15-0112 was used in Flow cytometry/Cell sorting to demonstrate roles for retinoid signaling and the DERARE in maintaining HSCs and preventing leukemogenesis by coordinate regulation of Hoxb genes.</div> <div itemprodp="datePublished">Thu May 03 00:00:00 EDT 2018</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/29415889"> <div itemprop="name">iRhom2-mediated proinflammatory signalling regulates heart repair following myocardial infarction.</div> </a> <div itemprop="about">JCI insight</div> <div itemprop="author">Barnette DN,Cahill TJ,Gunadasa-Rohling M,Carr CA,Freeman M,Riley PR</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Thu Feb 08 00:00:00 EST 2018</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/29669931"> <div itemprop="name">Targeting the gut microbiome to treat the osteoarthritis of obesity.</div> </a> <div itemprop="about">JCI insight</div> <div itemprop="author">Schott EM,Farnsworth CW,Grier A,Lillis JA,Soniwala S,Dadourian GH,Bell RD,Doolittle ML,Villani DA,Awad H,Ketz JP,Kamal F,Ackert-Bicknell C,Ashton JM,Gill SR,Mooney RA,Zuscik MJ</div> <div itemprop="description">15-0112 was used in Flow cytometry/Cell sorting to show that reducing Tnf-associated inflammation in obesity is profoundly protective against osteoarthritis in mice.</div> <div itemprodp="datePublished">Thu Apr 19 00:00:00 EDT 2018</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/29670088"> <div itemprop="name">A cancer vaccine-mediated postoperative immunotherapy for recurrent and metastatic tumors.</div> </a> <div itemprop="about">Nature communications</div> <div itemprop="author">Wang T,Wang D,Yu H,Feng B,Zhou F,Zhang H,Zhou L,Jiao S,Li Y</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Wed Apr 18 00:00:00 EDT 2018</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/30254630"> <div itemprop="name">Diet-Induced Obesity Elicits Macrophage Infiltration and Reduction in Spine Density in the Hypothalami of Male but Not Female Mice.</div> </a> <div itemprop="about">Frontiers in immunology</div> <div itemprop="author">Lainez NM,Jonak CR,Nair MG,Ethell IM,Wilson EH,Carson MJ,Coss D</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Wed Sep 25 00:00:00 EDT 2019</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/30241479"> <div itemprop="name">Microglia prevent peripheral immune cell invasion and promote an anti-inflammatory environment in the brain of APP-PS1 transgenic mice.</div> </a> <div itemprop="about">Journal of neuroinflammation</div> <div itemprop="author">Unger MS,Schernthaner P,Marschallinger J,Mrowetz H,Aigner L</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Fri Sep 21 00:00:00 EDT 2018</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/29774117"> <div itemprop="name">Investigation of tumor-tumor interactions in a double human cervical carcinoma xenograft model in nude mice.</div> </a> <div itemprop="about">Oncotarget</div> <div itemprop="author">Mertens B,Cristina de Araujo Nogueira T,Topalis D,Stranska R,Snoeck R,Andrei G</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Tue Apr 24 00:00:00 EDT 2018</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/29707136"> <div itemprop="name">BNIP3 modulates the interface between B16-F10 melanoma cells and immune cells.</div> </a> <div itemprop="about">Oncotarget</div> <div itemprop="author">Romano E,Rufo N,Korf H,Mathieu C,Garg AD,Agostinis P</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Tue Apr 03 00:00:00 EDT 2018</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/30389997"> <div itemprop="name">An immune cell spray (ICS) formulation allows for the delivery of functional monocyte/macrophages.</div> </a> <div itemprop="about">Scientific reports</div> <div itemprop="author">Beneke V,Küster F,Neehus AL,Hesse C,Lopez-Rodriguez E,Haake K,Rafiei Hashtchin A,Schott JW,Walter D,Braun A,Wolkers WF,Ackermann M,Lachmann N</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Fri Nov 02 00:00:00 EDT 2018</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/29483875"> <div itemprop="name">Macrophage Depletion Protects against Cigarette Smoke-Induced Inflammatory Response in the Mouse Colon and Lung.</div> </a> <div itemprop="about">Frontiers in physiology</div> <div itemprop="author">Lim D,Kim W,Lee C,Bae H,Kim J</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Wed Sep 30 00:00:00 EDT 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/29700112"> <div itemprop="name">RhoA, Rac1, and Cdc42 differentially regulate αSMA and collagen I expression in mesenchymal stem cells.</div> </a> <div itemprop="about">The Journal of biological chemistry</div> <div itemprop="author">Ge J,Burnier L,Adamopoulou M,Kwa MQ,Schaks M,Rottner K,Brakebusch C</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Fri Jun 15 00:00:00 EDT 2018</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/28112734"> <div itemprop="name">JNK1 negatively controls antifungal innate immunity by suppressing CD23 expression.</div> </a> <div itemprop="about">Nature medicine</div> <div itemprop="author">Zhao X,Guo Y,Jiang C,Chang Q,Zhang S,Luo T,Zhang B,Jia X,Hung MC,Dong C,Lin X</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Wed Mar 01 00:00:00 EST 2017</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/28355185"> <div itemprop="name">Myeloid progenitor cluster formation drives emergency and leukaemic myelopoiesis.</div> </a> <div itemprop="about">Nature</div> <div itemprop="author">Hérault A,Binnewies M,Leong S,Calero-Nieto FJ,Zhang SY,Kang YA,Wang X,Pietras EM,Chu SH,Barry-Holson K,Armstrong S,Göttgens B,Passegué E</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Thu Apr 06 00:00:00 EDT 2017</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/28489818"> <div itemprop="name">A Wnt-producing niche drives proliferative potential and progression in lung adenocarcinoma.</div> </a> <div itemprop="about">Nature</div> <div itemprop="author">Tammela T,Sanchez-Rivera FJ,Cetinbas NM,Wu K,Joshi NS,Helenius K,Park Y,Azimi R,Kerper NR,Wesselhoeft RA,Gu X,Schmidt L,Cornwall-Brady M,Yilmaz ÖH,Xue W,Katajisto P,Bhutkar A,Jacks T</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Thu May 18 00:00:00 EDT 2017</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/29017059"> <div itemprop="name">Direct Activation of BAX by BTSA1 Overcomes Apoptosis Resistance in Acute Myeloid Leukemia.</div> </a> <div itemprop="about">Cancer cell</div> <div itemprop="author">Reyna DE,Garner TP,Lopez A,Kopp F,Choudhary GS,Sridharan A,Narayanagari SR,Mitchell K,Dong B,Bartholdy BA,Walensky LD,Verma A,Steidl U,Gavathiotis E</div> <div itemprop="description">15-0112 was used in Flow cytometry/Cell sorting to identify BTSA1, a pharmacologically optimised BAX activator that binds with high affinity and specificity to the N-terminal activation site and induces conformational changes to BAX leading to BAX-mediated apoptosis.</div> <div itemprodp="datePublished">Mon Oct 09 00:00:00 EDT 2017</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/29174402"> <div itemprop="name">Commensal Fungi Recapitulate the Protective Benefits of Intestinal Bacteria.</div> </a> <div itemprop="about">Cell host & microbe</div> <div itemprop="author">Jiang TT,Shao TY,Ang WXG,Kinder JM,Turner LH,Pham G,Whitt J,Alenghat T,Way SS</div> <div itemprop="description">15-0112-82 was used in Flow Cytometry to show that commensal fungi can functionally replace intestinal bacteria by conferring protection against injury to mucosal tissues and positively calibrating the responsiveness of circulating immune cells.</div> <div itemprodp="datePublished">Wed Dec 13 00:00:00 EST 2017</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/28024152"> <div itemprop="name">Ubiquitination of hnRNPA1 by TRAF6 links chronic innate immune signaling with myelodysplasia.</div> </a> <div itemprop="about">Nature immunology</div> <div itemprop="author">Fang J,Bolanos LC,Choi K,Liu X,Christie S,Akunuru S,Kumar R,Wang D,Chen X,Greis KD,Stoilov P,Filippi MD,Maciejewski JP,Garcia-Manero G,Weirauch MT,Salomonis N,Geiger H,Zheng Y,Starczynowski DT</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Wed Feb 01 00:00:00 EST 2017</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/28024152"> <div itemprop="name">Ubiquitination of hnRNPA1 by TRAF6 links chronic innate immune signaling with myelodysplasia.</div> </a> <div itemprop="about">Nature immunology</div> <div itemprop="author">Fang J,Bolanos LC,Choi K,Liu X,Christie S,Akunuru S,Kumar R,Wang D,Chen X,Greis KD,Stoilov P,Filippi MD,Maciejewski JP,Garcia-Manero G,Weirauch MT,Salomonis N,Geiger H,Zheng Y,Starczynowski DT</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Wed Feb 01 00:00:00 EST 2017</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/28134623"> <div itemprop="name">A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer.</div> </a> <div itemprop="about">The Journal of clinical investigation</div> <div itemprop="author">Berlato C,Khan MN,Schioppa T,Thompson R,Maniati E,Montfort A,Jangani M,Canosa M,Kulbe H,Hagemann UB,Duncan AR,Fletcher L,Wilkinson RW,Powles T,Quezada SA,Balkwill FR</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Wed Mar 01 00:00:00 EST 2017</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/28533230"> <div itemprop="name">Deletion of PIKfyve alters alveolar macrophage populations and exacerbates allergic inflammation in mice.</div> </a> <div itemprop="about">The EMBO journal</div> <div itemprop="author">Kawasaki T,Ito K,Miyata H,Akira S,Kawai T</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Wed Jun 14 00:00:00 EDT 2017</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/28461486"> <div itemprop="name">Brd4 modulates the innate immune response through Mnk2-eIF4E pathway-dependent translational control of IκBα.</div> </a> <div itemprop="about">Proceedings of the National Academy of Sciences of the United States of America</div> <div itemprop="author">Bao Y,Wu X,Chen J,Hu X,Zeng F,Cheng J,Jin H,Lin X,Chen LF</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Tue May 16 00:00:00 EDT 2017</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/28120849"> <div itemprop="name">CCR2<sup>-</sup> and CCR2<sup>+</sup> corneal macrophages exhibit distinct characteristics and balance inflammatory responses after epithelial abrasion.</div> </a> <div itemprop="about">Mucosal immunology</div> <div itemprop="author">Liu J,Xue Y,Dong D,Xiao C,Lin C,Wang H,Song F,Fu T,Wang Z,Chen J,Pan H,Li Y,Cai D,Li Z</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Fri Sep 01 00:00:00 EDT 2017</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/28273719"> <div itemprop="name">Depletion of microglia exacerbates postischemic inflammation and brain injury.</div> </a> <div itemprop="about">Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism</div> <div itemprop="author">Jin WN,Shi SX,Li Z,Li M,Wood K,Gonzales RJ,Liu Q</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Thu Jun 01 00:00:00 EDT 2017</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/27928007"> <div itemprop="name">Mice Expressing Minimally Humanized CD81 and Occludin Genes Support Hepatitis C Virus Uptake In Vivo.</div> </a> <div itemprop="about">Journal of virology</div> <div itemprop="author">Ding Q,von Schaewen M,Hrebikova G,Heller B,Sandmann L,Plaas M,Ploss A</div> <div itemprop="description">15-0112 was used in Flow cytometry/Cell sorting to demonstrate that minimally humanized mice develop normally, express the modified genes at physiological levels, and support Hepatitis C virus uptake.</div> <div itemprodp="datePublished">Wed Feb 15 00:00:00 EST 2017</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/28052488"> <div itemprop="name">Lymphatic Endothelial Cells Produce M-CSF, Causing Massive Bone Loss in Mice.</div> </a> <div itemprop="about">Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research</div> <div itemprop="author">Wang W,Wang H,Zhou X,Li X,Sun W,Dellinger M,Boyce BF,Xing L</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Mon May 01 00:00:00 EDT 2017</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/28674181"> <div itemprop="name">Lung Epithelial Cell-Derived Microvesicles Regulate Macrophage Migration via MicroRNA-17/221-Induced Integrin β<sub>1</sub> Recycling.</div> </a> <div itemprop="about">Journal of immunology (Baltimore, Md. : 1950)</div> <div itemprop="author">Lee H,Zhang D,Wu J,Otterbein LE,Jin Y</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Tue Aug 15 00:00:00 EDT 2017</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/28350048"> <div itemprop="name">Silybin attenuates LPS-induced lung injury in mice by inhibiting NF-κB signaling and NLRP3 activation.</div> </a> <div itemprop="about">International journal of molecular medicine</div> <div itemprop="author">Zhang B,Wang B,Cao S,Wang Y,Wu D</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Mon May 01 00:00:00 EDT 2017</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/27362366"> <div itemprop="name">ADAR1 deletion induces NFκB and interferon signaling dependent liver inflammation and fibrosis.</div> </a> <div itemprop="about">RNA biology</div> <div itemprop="author">Ben-Shoshan SO,Kagan P,Sultan M,Barabash Z,Dor C,Jacob-Hirsch J,Harmelin A,Pappo O,Marcu-Malina V,Ben-Ari Z,Amariglio N,Rechavi G,Goldstein I,Safran M</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Thu May 04 00:00:00 EDT 2017</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/28513874"> <div itemprop="name">β3-Adrenergic Regulation of EPC Features Through Manipulation of the Bone Marrow MSC Niche.</div> </a> <div itemprop="about">Journal of cellular biochemistry</div> <div itemprop="author">Vafaei R,Nassiri SM,Siavashi V</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Fri Dec 01 00:00:00 EST 2017</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/28205389"> <div itemprop="name">Growth inhibition of formed corneal neovascularization following Fosaprepitant treatment.</div> </a> <div itemprop="about">Acta ophthalmologica</div> <div itemprop="author">Bignami F,Lorusso A,Rama P,Ferrari G</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Wed Nov 01 00:00:00 EDT 2017</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/28273337"> <div itemprop="name">Ethanol, TLR3, and TLR4 Agonists Have Unique Innate Immune Responses in Neuron-Like SH-SY5Y and Microglia-Like BV2.</div> </a> <div itemprop="about">Alcoholism, clinical and experimental research</div> <div itemprop="author">Lawrimore CJ,Crews FT</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Mon May 01 00:00:00 EDT 2017</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/29069761"> <div itemprop="name">Myeloid-specific genetic ablation of ATP-binding cassette transporter ABCA1 is protective against cancer.</div> </a> <div itemprop="about">Oncotarget</div> <div itemprop="author">Zamanian-Daryoush M,Lindner DJ,DiDonato JA,Wagner M,Buffa J,Rayman P,Parks JS,Westerterp M,Tall AR,Hazen SL</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Fri Sep 22 00:00:00 EDT 2017</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/28874817"> <div itemprop="name">Armored CAR T cells enhance antitumor efficacy and overcome the tumor microenvironment.</div> </a> <div itemprop="about">Scientific reports</div> <div itemprop="author">Yeku OO,Purdon TJ,Koneru M,Spriggs D,Brentjens RJ</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Tue Sep 05 00:00:00 EDT 2017</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/28976973"> <div itemprop="name">MiR-125a Is a critical modulator for neutrophil development.</div> </a> <div itemprop="about">PLoS genetics</div> <div itemprop="author">Qin Y,Wu L,Ouyang Y,Zhou P,Zhou H,Wang Y,Ma J,Zhang J,Chen Y,Qian J,Tang Y,Shen N</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Sun Oct 01 00:00:00 EDT 2017</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/29126435"> <div itemprop="name">Human amnion cells reverse acute and chronic pulmonary damage in experimental neonatal lung injury.</div> </a> <div itemprop="about">Stem cell research & therapy</div> <div itemprop="author">Zhu D,Tan J,Maleken AS,Muljadi R,Chan ST,Lau SN,Elgass K,Leaw B,Mockler J,Chambers D,Leeman KT,Kim CF,Wallace EM,Lim R</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Fri Nov 10 00:00:00 EST 2017</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/29312584"> <div itemprop="name">Recipient bone marrow assimilates the myeloid/lymphoid reconstitution of distinct fetal hematopoietic stem cells.</div> </a> <div itemprop="about">Oncotarget</div> <div itemprop="author">Guo XL,Chu L,Ke F,Mu LL,Li Z,Cai JJ,Li HF,Hong DL</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Tue Dec 12 00:00:00 EST 2017</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/28569792"> <div itemprop="name">Loss of epidermal AP1 transcription factor function reduces filaggrin level, alters chemokine expression and produces an ichthyosis-related phenotype.</div> </a> <div itemprop="about">Cell death & disease</div> <div itemprop="author">Young CA,Rorke EA,Adhikary G,Xu W,Eckert RL</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Thu Jun 01 00:00:00 EDT 2017</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/29263862"> <div itemprop="name">Neutrophil swarming and extracellular trap formation play a significant role in Alum adjuvant activity.</div> </a> <div itemprop="about">NPJ vaccines</div> <div itemprop="author">Stephen J,Scales HE,Benson RA,Erben D,Garside P,Brewer JM</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Fri Apr 08 00:00:00 EDT 2022</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/28410606"> <div itemprop="name">In vivo quantification of quantum dot systemic transport in C57BL/6 hairless mice following skin application post-ultraviolet radiation.</div> </a> <div itemprop="about">Particle and fibre toxicology</div> <div itemprop="author">Jatana S,Palmer BC,Phelan SJ,Gelein R,DeLouise LA</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Fri Apr 14 00:00:00 EDT 2017</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/28515366"> <div itemprop="name">Experimental lupus is aggravated in mouse strains with impaired induction of neutrophil extracellular traps.</div> </a> <div itemprop="about">JCI insight</div> <div itemprop="author">Kienhöfer D,Hahn J,Stoof J,Csepregi JZ,Reinwald C,Urbonaviciute V,Johnsson C,Maueröder C,Podolska MJ,Biermann MH,Leppkes M,Harrer T,Hultqvist M,Olofsson P,Munoz LE,Mocsai A,Herrmann M,Schett G,Holmdahl R,Hoffmann MH</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Thu May 18 00:00:00 EDT 2017</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/29038540"> <div itemprop="name">Regulation of endothelial intracellular adenosine via adenosine kinase epigenetically modulates vascular inflammation.</div> </a> <div itemprop="about">Nature communications</div> <div itemprop="author">Xu Y,Wang Y,Yan S,Yang Q,Zhou Y,Zeng X,Liu Z,An X,Toque HA,Dong Z,Jiang X,Fulton DJ,Weintraub NL,Li Q,Bagi Z,Hong M,Boison D,Wu C,Huo Y</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Mon Oct 16 00:00:00 EDT 2017</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/28197387"> <div itemprop="name">CIITA-driven MHC class II expressing tumor cells can efficiently prime naive CD4<sup>+</sup> TH cells <i>in vivo</i> and vaccinate the host against parental MHC-II-negative tumor cells.</div> </a> <div itemprop="about">Oncoimmunology</div> <div itemprop="author">Bou Nasser Eddine F,Forlani G,Lombardo L,Tedeschi A,Tosi G,Accolla RS</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Tue Jan 12 00:00:00 EST 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/28931759"> <div itemprop="name">Combination immunotherapy with TLR agonists and checkpoint inhibitors suppresses head and neck cancer.</div> </a> <div itemprop="about">JCI insight</div> <div itemprop="author">Sato-Kaneko F,Yao S,Ahmadi A,Zhang SS,Hosoya T,Kaneda MM,Varner JA,Pu M,Messer KS,Guiducci C,Coffman RL,Kitaura K,Matsutani T,Suzuki R,Carson DA,Hayashi T,Cohen EE</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Thu Sep 21 00:00:00 EDT 2017</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/27716507"> <div itemprop="name">Host-Protozoan Interactions Protect from Mucosal Infections through Activation of the Inflammasome.</div> </a> <div itemprop="about">Cell</div> <div itemprop="author">Chudnovskiy A,Mortha A,Kana V,Kennard A,Ramirez JD,Rahman A,Remark R,Mogno I,Ng R,Gnjatic S,Amir ED,Solovyov A,Greenbaum B,Clemente J,Faith J,Belkaid Y,Grigg ME,Merad M</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Thu Oct 06 00:00:00 EDT 2016</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/27523608"> <div itemprop="name">The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity.</div> </a> <div itemprop="about">Cell</div> <div itemprop="author">Damgaard RB,Walker JA,Marco-Casanova P,Morgan NV,Titheradge HL,Elliott PR,McHale D,Maher ER,McKenzie ANJ,Komander D</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Thu Aug 25 00:00:00 EDT 2016</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/27019226"> <div itemprop="name">Classical dendritic cells are required for dietary antigen-mediated induction of peripheral T(reg) cells and tolerance.</div> </a> <div itemprop="about">Nature immunology</div> <div itemprop="author">Esterházy D,Loschko J,London M,Jove V,Oliveira TY,Mucida D</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Sun May 01 00:00:00 EDT 2016</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/26656646"> <div itemprop="name">Oligodendrocyte death results in immune-mediated CNS demyelination.</div> </a> <div itemprop="about">Nature neuroscience</div> <div itemprop="author">Traka M,Podojil JR,McCarthy DP,Miller SD,Popko B</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Fri Jan 01 00:00:00 EST 2016</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/26277898"> <div itemprop="name">The breast tumor microenvironment alters the phenotype and function of natural killer cells.</div> </a> <div itemprop="about">Cellular & molecular immunology</div> <div itemprop="author">Krneta T,Gillgrass A,Chew M,Ashkar AA</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Thu Sep 01 00:00:00 EDT 2016</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/27140396"> <div itemprop="name">Alternatively activated macrophages determine repair of the infarcted adult murine heart.</div> </a> <div itemprop="about">The Journal of clinical investigation</div> <div itemprop="author">Shiraishi M,Shintani Y,Shintani Y,Ishida H,Saba R,Yamaguchi A,Adachi H,Yashiro K,Suzuki K</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Wed Jun 01 00:00:00 EDT 2016</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/28018360"> <div itemprop="name">ATP-Induced Inflammasome Activation and Pyroptosis Is Regulated by AMP-Activated Protein Kinase in Macrophages.</div> </a> <div itemprop="about">Frontiers in immunology</div> <div itemprop="author">Zha QB,Wei HX,Li CG,Liang YD,Xu LH,Bai WJ,Pan H,He XH,Ouyang DY</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Wed Nov 20 00:00:00 EST 2019</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/27352928"> <div itemprop="name">Opposite Effects of Coinjection and Distant Injection of Mesenchymal Stem Cells on Breast Tumor Cell Growth.</div> </a> <div itemprop="about">Stem cells translational medicine</div> <div itemprop="author">Zheng H,Zou W,Shen J,Xu L,Wang S,Fu YX,Fan W</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Thu Sep 01 00:00:00 EDT 2016</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/27278624"> <div itemprop="name">Macrophages transfer antigens to dendritic cells by releasing exosomes containing dead-cell-associated antigens partially through a ceramide-dependent pathway to enhance CD4(+) T-cell responses.</div> </a> <div itemprop="about">Immunology</div> <div itemprop="author">Xu Y,Liu Y,Yang C,Kang L,Wang M,Hu J,He H,Song W,Tang H</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Sat Oct 01 00:00:00 EDT 2016</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/27158241"> <div itemprop="name">Ginsenoside Rd alleviates mouse acute renal ischemia/reperfusion injury by modulating macrophage phenotype.</div> </a> <div itemprop="about">Journal of ginseng research</div> <div itemprop="author">Ren K,Jin C,Ma P,Ren Q,Jia Z,Zhu D</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Fri Apr 01 00:00:00 EDT 2016</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/26794131"> <div itemprop="name">Multimodal analysis of ocular inflammation using the endotoxin-induced uveitis mouse model.</div> </a> <div itemprop="about">Disease models & mechanisms</div> <div itemprop="author">Chu CJ,Gardner PJ,Copland DA,Liyanage SE,Gonzalez-Cordero A,Kleine Holthaus SM,Luhmann UF,Smith AJ,Ali RR,Dick AD</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Fri Apr 01 00:00:00 EDT 2016</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/27247575"> <div itemprop="name">Regenerative Potential of Mesenchymal Stromal Cells: Age-Related Changes.</div> </a> <div itemprop="about">Stem cells international</div> <div itemprop="author">Bruna F,Contador D,Conget P,Erranz B,Sossa CL,Arango-Rodríguez ML</div> <div itemprop="description">15-0112 was used in Flow cytometry/Cell sorting to suggest, the treatment with adult''s BM-MSCs or their acd-MSCs in cutaneous wound promotes a better tissue repair/regeneration.</div> <div itemprodp="datePublished">Wed Jun 01 00:00:00 EDT 2016</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/26756870"> <div itemprop="name">ECM-Dependence of Endothelial Progenitor Cell Features.</div> </a> <div itemprop="about">Journal of cellular biochemistry</div> <div itemprop="author">Siavashi V,Nassiri SM,Rahbarghazi R,Vafaei R,Sariri R</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Mon Aug 01 00:00:00 EDT 2016</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/27172151"> <div itemprop="name">Tlr2 on Bone Marrow and Non-Bone Marrow Derived Cells Regulates Inflammation and Organ Injury in Cooperation with Tlr4 During Resuscitated Hemorrhagic Shock.</div> </a> <div itemprop="about">Shock (Augusta, Ga.)</div> <div itemprop="author">Korff S,Loughran P,Cai C,Fan J,Elson G,Shang L,Pires SS,Lee YS,Guardado J,Scott M,Billiar TR</div> <div itemprop="description">15-0112 was used in Flow cytometry/Cell sorting to conclude that TLR2 and TLR4 act together as important receptors in the host immune response to hemorrhagic shock and resuscitation.</div> <div itemprodp="datePublished">Tue Nov 01 00:00:00 EDT 2016</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/27917274"> <div itemprop="name">Sertoli cell condition medium can induce germ like cells from bone marrow derived mesenchymal stem cells.</div> </a> <div itemprop="about">Iranian journal of basic medical sciences</div> <div itemprop="author">Monfared MH,Minaee B,Rastegar T,Khrazinejad E,Barbarestani M</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Tue Nov 01 00:00:00 EDT 2016</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/27453007"> <div itemprop="name">Murine iPSC-Derived Macrophages as a Tool for Disease Modeling of Hereditary Pulmonary Alveolar Proteinosis due to Csf2rb Deficiency.</div> </a> <div itemprop="about">Stem cell reports</div> <div itemprop="author">Mucci A,Kunkiel J,Suzuki T,Brennig S,Glage S,Kühnel MP,Ackermann M,Happle C,Kuhn A,Schambach A,Trapnell BC,Hansen G,Moritz T,Lachmann N</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Tue Aug 09 00:00:00 EDT 2016</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/27468693"> <div itemprop="name">Activated c-Kit receptor in the heart promotes cardiac repair and regeneration after injury.</div> </a> <div itemprop="about">Cell death & disease</div> <div itemprop="author">Di Siena S,Gimmelli R,Nori SL,Barbagallo F,Campolo F,Dolci S,Rossi P,Venneri MA,Giannetta E,Gianfrilli D,Feigenbaum L,Lenzi A,Naro F,Cianflone E,Mancuso T,Torella D,Isidori AM,Pellegrini M</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Thu Jul 28 00:00:00 EDT 2016</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/27622015"> <div itemprop="name">Ranitidine modifies myeloid cell populations and inhibits breast tumor development and spread in mice.</div> </a> <div itemprop="about">Oncoimmunology</div> <div itemprop="author">Vila-Leahey A,Oldford SA,Marignani PA,Wang J,Haidl ID,Marshall JS</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Fri Jul 01 00:00:00 EDT 2016</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/26810896"> <div itemprop="name">CpG-oligodeoxynucleotides exert remarkable antitumor activity against diffuse malignant peritoneal mesothelioma orthotopic xenografts.</div> </a> <div itemprop="about">Journal of translational medicine</div> <div itemprop="author">De Cesare M,Sfondrini L,Pennati M,De Marco C,Motta V,Tagliabue E,Deraco M,Balsari A,Zaffaroni N</div> <div itemprop="description">15-0112 was used in Flow cytometry/Cell sorting to indicate that locally administered CpG-ODN1826 is able to markedly affect the growth of both early- and late-stage DMPM orthotopic xenografts in the absence of severe side effects.</div> <div itemprodp="datePublished">Mon Jan 25 00:00:00 EST 2016</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/27942589"> <div itemprop="name">Interleukin 6 regulates psoriasiform inflammation-associated thrombosis.</div> </a> <div itemprop="about">JCI insight</div> <div itemprop="author">Wang Y,Golden JB,Fritz Y,Zhang X,Diaconu D,Camhi MI,Gao H,Dawes SM,Xing X,Ganesh SK,Gudjonsson JE,Simon DI,McCormick TS,Ward NL</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Thu Dec 08 00:00:00 EST 2016</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/27428079"> <div itemprop="name">Alkylator-Induced and Patient-Derived Xenograft Mouse Models of Therapy-Related Myeloid Neoplasms Model Clinical Disease and Suggest the Presence of Multiple Cell Subpopulations with Leukemia Stem Cell Activity.</div> </a> <div itemprop="about">PloS one</div> <div itemprop="author">Jonas BA,Johnson C,Gratzinger D,Majeti R</div> <div itemprop="description">15-0112 was used in Flow cytometry/Cell sorting to report several new t-AML/MDS mouse models that could potentially be used to further define disease pathogenesis and test novel therapeutics.</div> <div itemprodp="datePublished">Wed Jul 26 00:00:00 EDT 2017</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/27405096"> <div itemprop="name">Stroke sensitivity in the aged: sex chromosome complement vs. gonadal hormones.</div> </a> <div itemprop="about">Aging</div> <div itemprop="author">McCullough LD,Mirza MA,Xu Y,Bentivegna K,Steffens EB,Ritzel R,Liu F</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Fri Jul 01 00:00:00 EDT 2016</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/27601261"> <div itemprop="name">NK cell development requires Tsc1-dependent negative regulation of IL-15-triggered mTORC1 activation.</div> </a> <div itemprop="about">Nature communications</div> <div itemprop="author">Yang M,Chen S,Du J,He J,Wang Y,Li Z,Liu G,Peng W,Zeng X,Li D,Xu P,Guo W,Chang Z,Wang S,Tian Z,Dong Z</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Wed Sep 07 00:00:00 EDT 2016</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/26863636"> <div itemprop="name">The impact of ranitidine on monocyte responses in the context of solid tumors.</div> </a> <div itemprop="about">Oncotarget</div> <div itemprop="author">Vila-Leahey A,Rogers D,Marshall JS</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Tue Mar 08 00:00:00 EST 2016</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/26778110"> <div itemprop="name">Impaired differentiation of macrophage lineage cells attenuates bone remodeling and inflammatory angiogenesis in Ndrg1 deficient mice.</div> </a> <div itemprop="about">Scientific reports</div> <div itemprop="author">Watari K,Shibata T,Nabeshima H,Shinoda A,Fukunaga Y,Kawahara A,Karasuyama K,Fukushi J,Iwamoto Y,Kuwano M,Ono M</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Mon Jan 18 00:00:00 EST 2016</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/27057467"> <div itemprop="name">Irradiation of necrotic cancer cells, employed for pulsing dendritic cells (DCs), potentiates DC vaccine-induced antitumor immunity against high-grade glioma.</div> </a> <div itemprop="about">Oncoimmunology</div> <div itemprop="author">Vandenberk L,Garg AD,Verschuere T,Koks C,Belmans J,Beullens M,Agostinis P,De Vleeschouwer S,Van Gool SW</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Mon Feb 01 00:00:00 EST 2016</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/27302484"> <div itemprop="name">Diet-dependent, microbiota-independent regulation of IL-10-producing lamina propria macrophages in the small intestine.</div> </a> <div itemprop="about">Scientific reports</div> <div itemprop="author">Ochi T,Feng Y,Kitamoto S,Nagao-Kitamoto H,Kuffa P,Atarashi K,Honda K,Teitelbaum DH,Kamada N</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Wed Jun 15 00:00:00 EDT 2016</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/25985364"> <div itemprop="name">KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis.</div> </a> <div itemprop="about">Nature medicine</div> <div itemprop="author">Shankman LS,Gomez D,Cherepanova OA,Salmon M,Alencar GF,Haskins RM,Swiatlowska P,Newman AA,Greene ES,Straub AC,Isakson B,Randolph GJ,Owens GK</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Mon Jun 01 00:00:00 EDT 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/26030851"> <div itemprop="name">Host microbiota constantly control maturation and function of microglia in the CNS.</div> </a> <div itemprop="about">Nature neuroscience</div> <div itemprop="author">Erny D,Hrabě de Angelis AL,Jaitin D,Wieghofer P,Staszewski O,David E,Keren-Shaul H,Mahlakoiv T,Jakobshagen K,Buch T,Schwierzeck V,Utermöhlen O,Chun E,Garrett WS,McCoy KD,Diefenbach A,Staeheli P,Stecher B,Amit I,Prinz M</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Wed Jul 01 00:00:00 EDT 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/26447190"> <div itemprop="name">Functional-genetic dissection of HDAC dependencies in mouse lymphoid and myeloid malignancies.</div> </a> <div itemprop="about">Blood</div> <div itemprop="author">Matthews GM,Mehdipour P,Cluse LA,Falkenberg KJ,Wang E,Roth M,Santoro F,Vidacs E,Stanley K,House CM,Rusche JR,Vakoc CR,Zuber J,Minucci S,Johnstone RW</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Thu Nov 19 00:00:00 EST 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/26075824"> <div itemprop="name">Apoptotic cells trigger a membrane-initiated pathway to increase ABCA1.</div> </a> <div itemprop="about">The Journal of clinical investigation</div> <div itemprop="author">Fond AM,Lee CS,Schulman IG,Kiss RS,Ravichandran KS</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Wed Jul 01 00:00:00 EDT 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/26436647"> <div itemprop="name">MicroRNA-223 is a crucial mediator of PPARγ-regulated alternative macrophage activation.</div> </a> <div itemprop="about">The Journal of clinical investigation</div> <div itemprop="author">Ying W,Tseng A,Chang RC,Morin A,Brehm T,Triff K,Nair V,Zhuang G,Song H,Kanameni S,Wang H,Golding MC,Bazer FW,Chapkin RS,Safe S,Zhou B</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Mon Nov 02 00:00:00 EST 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/26551682"> <div itemprop="name">Aging-associated inflammation promotes selection for adaptive oncogenic events in B cell progenitors.</div> </a> <div itemprop="about">The Journal of clinical investigation</div> <div itemprop="author">Henry CJ,Casás-Selves M,Kim J,Zaberezhnyy V,Aghili L,Daniel AE,Jimenez L,Azam T,McNamee EN,Clambey ET,Klawitter J,Serkova NJ,Tan AC,Dinarello CA,DeGregori J</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Tue Dec 01 00:00:00 EST 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/26457732"> <div itemprop="name">STK4 regulates TLR pathways and protects against chronic inflammation-related hepatocellular carcinoma.</div> </a> <div itemprop="about">The Journal of clinical investigation</div> <div itemprop="author">Li W,Xiao J,Zhou X,Xu M,Hu C,Xu X,Lu Y,Liu C,Xue S,Nie L,Zhang H,Li Z,Zhang Y,Ji F,Hui L,Tao W,Wei B,Wang H</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Mon Nov 02 00:00:00 EST 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24824608"> <div itemprop="name">Hepatic DNA deposition drives drug-induced liver injury and inflammation in mice.</div> </a> <div itemprop="about">Hepatology (Baltimore, Md.)</div> <div itemprop="author">Marques PE,Oliveira AG,Pereira RV,David BA,Gomides LF,Saraiva AM,Pires DA,Novaes JT,Patricio DO,Cisalpino D,Menezes-Garcia Z,Leevy WM,Chapman SE,Mahecha G,Marques RE,Guabiraba R,Martins VP,Souza DG,Mansur DS,Teixeira MM,Leite MF,Menezes GB</div> <div itemprop="description">15-0112 was used in Flow cytometry/Cell sorting to examine whether DNA released from damaged hepatocytes accumulates into necrotic liver, and study the impact of its recognition by the immune system.</div> <div itemprodp="datePublished">Thu Jan 01 00:00:00 EST 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/26463675"> <div itemprop="name">Retinoid X receptor activation reverses age-related deficiencies in myelin debris phagocytosis and remyelination.</div> </a> <div itemprop="about">Brain : a journal of neurology</div> <div itemprop="author">Natrajan MS,de la Fuente AG,Crawford AH,Linehan E,Nuñez V,Johnson KR,Wu T,Fitzgerald DC,Ricote M,Bielekova B,Franklin RJ</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Tue Dec 01 00:00:00 EST 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/25556169"> <div itemprop="name">Tamm-Horsfall Protein Regulates Granulopoiesis and Systemic Neutrophil Homeostasis.</div> </a> <div itemprop="about">Journal of the American Society of Nephrology : JASN</div> <div itemprop="author">Micanovic R,Chitteti BR,Dagher PC,Srour EF,Khan S,Hato T,Lyle A,Tong Y,Wu XR,El-Achkar TM</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Tue Sep 01 00:00:00 EDT 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/26601269"> <div itemprop="name">Cis-regulatory mechanisms governing stem and progenitor cell transitions.</div> </a> <div itemprop="about">Science advances</div> <div itemprop="author">Johnson KD,Kong G,Gao X,Chang YI,Hewitt KJ,Sanalkumar R,Prathibha R,Ranheim EA,Dewey CN,Zhang J,Bresnick EH</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Tue Sep 01 00:00:00 EDT 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/25846981"> <div itemprop="name">Identification of a chronic non-neurodegenerative microglia activation state in a mouse model of peroxisomal β-oxidation deficiency.</div> </a> <div itemprop="about">Glia</div> <div itemprop="author">Verheijden S,Beckers L,Casazza A,Butovsky O,Mazzone M,Baes M</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Tue Sep 01 00:00:00 EDT 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/25690519"> <div itemprop="name">Aging-like changes in the transcriptome of irradiated microglia.</div> </a> <div itemprop="about">Glia</div> <div itemprop="author">Li MD,Burns TC,Kumar S,Morgan AA,Sloan SA,Palmer TD</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Fri May 01 00:00:00 EDT 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/25764512"> <div itemprop="name">Chitin recognition via chitotriosidase promotes pathologic type-2 helper T cell responses to cryptococcal infection.</div> </a> <div itemprop="about">PLoS pathogens</div> <div itemprop="author">Wiesner DL,Specht CA,Lee CK,Smith KD,Mukaremera L,Lee ST,Lee CG,Elias JA,Nielsen JN,Boulware DR,Bohjanen PR,Jenkins MK,Levitz SM,Nielsen K</div> <div itemprop="description">15-0112 was used in Flow cytometry/Cell sorting to investigate Th2 cell responses to pulmonary fungal infection, showing that chitin recognition via chitotriosidase promotes pathologic type-2 helper T cell responses to cryptococcal infection.</div> <div itemprodp="datePublished">Sun Mar 01 00:00:00 EST 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/25359083"> <div itemprop="name">Yersinia pestis targets neutrophils via complement receptor 3.</div> </a> <div itemprop="about">Cellular microbiology</div> <div itemprop="author">Merritt PM,Nero T,Bohman L,Felek S,Krukonis ES,Marketon MM</div> <div itemprop="description">15-0112 was used in Flow cytometry/Cell sorting to identify the factors involved in the targeting of murine splenocytes by Yersinia pestis.</div> <div itemprodp="datePublished">Fri May 01 00:00:00 EDT 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/25434326"> <div itemprop="name">Local delivery of VEGF and SDF enhances endothelial progenitor cell recruitment and resultant recovery from ischemia.</div> </a> <div itemprop="about">Tissue engineering. Part A</div> <div itemprop="author">Anderson EM,Kwee BJ,Lewin SA,Raimondo T,Mehta M,Mooney DJ</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Wed Apr 01 00:00:00 EDT 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/26096149"> <div itemprop="name">Reducing progression of experimental lupus nephritis via inhibition of the B7/CD28 signaling pathway.</div> </a> <div itemprop="about">Molecular medicine reports</div> <div itemprop="author">Huang L,Kong Y,Wang J,Sun J,Shi Q,Qiu YH</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Tue Sep 01 00:00:00 EDT 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/26491697"> <div itemprop="name">Targeted Mutation of Nuclear Bone Morphogenetic Protein 2 Impairs Secondary Immune Response in a Mouse Model.</div> </a> <div itemprop="about">BioMed research international</div> <div itemprop="author">Olsen DS,Goar WA,Nichols BA,Bailey KT,Christensen SL,Merriam KR,Reynolds PR,Wilson E,Weber KS,Bridgewater LC</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Mon Aug 01 00:00:00 EDT 2016</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/25931125"> <div itemprop="name">Granulocyte/Macrophage Colony-stimulating Factor-dependent Dendritic Cells Restrain Lean Adipose Tissue Expansion.</div> </a> <div itemprop="about">The Journal of biological chemistry</div> <div itemprop="author">Pamir N,Liu NC,Irwin A,Becker L,Peng Y,Ronsein GE,Bornfeldt KE,Duffield JS,Heinecke JW</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Fri Jun 05 00:00:00 EDT 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/25790768"> <div itemprop="name">The HIF-1/glial TIM-3 axis controls inflammation-associated brain damage under hypoxia.</div> </a> <div itemprop="about">Nature communications</div> <div itemprop="author">Koh HS,Chang CY,Jeon SB,Yoon HJ,Ahn YH,Kim HS,Kim IH,Jeon SH,Johnson RS,Park EJ</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Fri Mar 20 00:00:00 EDT 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/26333171"> <div itemprop="name">Mouse CD11b+Kupffer Cells Recruited from Bone Marrow Accelerate Liver Regeneration after Partial Hepatectomy.</div> </a> <div itemprop="about">PloS one</div> <div itemprop="author">Nishiyama K,Nakashima H,Ikarashi M,Kinoshita M,Nakashima M,Aosasa S,Seki S,Yamamoto J</div> <div itemprop="description">15-0112 was used in Flow cytometry/Cell sorting to investigate the role of Kupffer cells in liver regeneration after partial hepatectomy in mice.</div> <div itemprodp="datePublished">Mon May 23 00:00:00 EDT 2016</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/26465715"> <div itemprop="name">Sleep disruption impairs haematopoietic stem cell transplantation in mice.</div> </a> <div itemprop="about">Nature communications</div> <div itemprop="author">Rolls A,Pang WW,Ibarra I,Colas D,Bonnavion P,Korin B,Heller HC,Weissman IL,de Lecea L</div> <div itemprop="description">15-0112 was used in Flow cytometry/Cell sorting to provide insights into cellular and molecular mechanisms underlying the effects of sleep deprivation on HSCs.</div> <div itemprodp="datePublished">Wed Oct 14 00:00:00 EDT 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/26095772"> <div itemprop="name">Cancer-associated ASXL1 mutations may act as gain-of-function mutations of the ASXL1-BAP1 complex.</div> </a> <div itemprop="about">Nature communications</div> <div itemprop="author">Balasubramani A,Larjo A,Bassein JA,Chang X,Hastie RB,Togher SM,Lähdesmäki H,Rao A</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Mon Jun 22 00:00:00 EDT 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/25658639"> <div itemprop="name">Glioma-associated microglia/macrophages display an expression profile different from M1 and M2 polarization and highly express Gpnmb and Spp1.</div> </a> <div itemprop="about">PloS one</div> <div itemprop="author">Szulzewsky F,Pelz A,Feng X,Synowitz M,Markovic D,Langmann T,Holtman IR,Wang X,Eggen BJ,Boddeke HW,Hambardzumyan D,Wolf SA,Kettenmann H</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Tue Jan 12 00:00:00 EST 2016</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/26372309"> <div itemprop="name">dNP2 is a blood-brain barrier-permeable peptide enabling ctCTLA-4 protein delivery to ameliorate experimental autoimmune encephalomyelitis.</div> </a> <div itemprop="about">Nature communications</div> <div itemprop="author">Lim S,Kim WJ,Kim YH,Lee S,Koo JH,Lee JA,Yoon H,Kim DH,Park HJ,Kim HM,Lee HG,Yun Kim J,Lee JU,Hun Shin J,Kyun Kim L,Doh J,Kim H,Lee SK,Bothwell ALM,Suh M,Choi JM</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Tue Sep 15 00:00:00 EDT 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/26344905"> <div itemprop="name">Targeted Gene Correction in Osteopetrotic-Induced Pluripotent Stem Cells for the Generation of Functional Osteoclasts.</div> </a> <div itemprop="about">Stem cell reports</div> <div itemprop="author">Neri T,Muggeo S,Paulis M,Caldana ME,Crisafulli L,Strina D,Focarelli ML,Faggioli F,Recordati C,Scaramuzza S,Scanziani E,Mantero S,Buracchi C,Sobacchi C,Lombardo A,Naldini L,Vezzoni P,Villa A,Ficara F</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Tue Oct 13 00:00:00 EDT 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/26275291"> <div itemprop="name">Pathogenic Yersinia Promotes Its Survival by Creating an Acidic Fluid-Accessible Compartment on the Macrophage Surface.</div> </a> <div itemprop="about">PloS one</div> <div itemprop="author">Bahnan W,Boettner DR,Westermark L,Fällman M,Schesser K</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Tue May 10 00:00:00 EDT 2016</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/25949902"> <div itemprop="name">Sunitinib depletes myeloid-derived suppressor cells and synergizes with a cancer vaccine to enhance antigen-specific immune responses and tumor eradication.</div> </a> <div itemprop="about">Oncoimmunology</div> <div itemprop="author">Draghiciu O,Nijman HW,Hoogeboom BN,Meijerhof T,Daemen T</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Sun Mar 01 00:00:00 EST 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/26399548"> <div itemprop="name">Acute DNA damage activates the tumour suppressor p53 to promote radiation-induced lymphoma.</div> </a> <div itemprop="about">Nature communications</div> <div itemprop="author">Lee CL,Castle KD,Moding EJ,Blum JM,Williams N,Luo L,Ma Y,Borst LB,Kim Y,Kirsch DG</div> <div itemprop="description">15-0112 was used in Flow cytometry/Cell sorting to show that total-body irradiation promotes the expansion of a rare population of thymocytes that express oncogenic Kras(G12D).</div> <div itemprodp="datePublished">Thu Sep 24 00:00:00 EDT 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/25043024"> <div itemprop="name">Functional polarization of tumour-associated macrophages by tumour-derived lactic acid.</div> </a> <div itemprop="about">Nature</div> <div itemprop="author">Colegio OR,Chu NQ,Szabo AL,Chu T,Rhebergen AM,Jairam V,Cyrus N,Brokowski CE,Eisenbarth SC,Phillips GM,Cline GW,Phillips AJ,Medzhitov R</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Thu Sep 25 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24630724"> <div itemprop="name">Heme-mediated SPI-C induction promotes monocyte differentiation into iron-recycling macrophages.</div> </a> <div itemprop="about">Cell</div> <div itemprop="author">Haldar M,Kohyama M,So AY,Kc W,Wu X,Briseño CG,Satpathy AT,Kretzer NM,Arase H,Rajasekaran NS,Wang L,Egawa T,Igarashi K,Baltimore D,Murphy TL,Murphy KM</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Thu Mar 13 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24608040"> <div itemprop="name">A role for the ITAM signaling module in specifying cytokine-receptor functions.</div> </a> <div itemprop="about">Nature immunology</div> <div itemprop="author">Bezbradica JS,Rosenstein RK,DeMarco RA,Brodsky I,Medzhitov R</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Tue Apr 01 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/25326491"> <div itemprop="name">RAGE expression in tumor-associated macrophages promotes angiogenesis in glioma.</div> </a> <div itemprop="about">Cancer research</div> <div itemprop="author">Chen X,Zhang L,Zhang IY,Liang J,Wang H,Ouyang M,Wu S,da Fonseca ACC,Weng L,Yamamoto Y,Yamamoto H,Natarajan R,Badie B</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Mon Dec 15 00:00:00 EST 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/25536657"> <div itemprop="name">Macrophages contribute to the cyclic activation of adult hair follicle stem cells.</div> </a> <div itemprop="about">PLoS biology</div> <div itemprop="author">Castellana D,Paus R,Perez-Moreno M</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Mon Dec 01 00:00:00 EST 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24733756"> <div itemprop="name">Astrocytic transforming growth factor-beta signaling reduces subacute neuroinflammation after stroke in mice.</div> </a> <div itemprop="about">Glia</div> <div itemprop="author">Cekanaviciute E,Fathali N,Doyle KP,Williams AM,Han J,Buckwalter MS</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Fri Aug 01 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24850855"> <div itemprop="name">A crucial role for the ubiquitously expressed transcription factor Sp1 at early stages of hematopoietic specification.</div> </a> <div itemprop="about">Development (Cambridge, England)</div> <div itemprop="author">Gilmour J,Assi SA,Jaegle U,Kulu D,van de Werken H,Clarke D,Westhead DR,Philipsen S,Bonifer C</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Sun Jun 01 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24446236"> <div itemprop="name">Tracking the elusive fibrocyte: identification and characterization of collagen-producing hematopoietic lineage cells during murine wound healing.</div> </a> <div itemprop="about">Stem cells (Dayton, Ohio)</div> <div itemprop="author">Suga H,Rennert RC,Rodrigues M,Sorkin M,Glotzbach JP,Januszyk M,Fujiwara T,Longaker MT,Gurtner GC</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Thu May 01 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24446236"> <div itemprop="name">Tracking the elusive fibrocyte: identification and characterization of collagen-producing hematopoietic lineage cells during murine wound healing.</div> </a> <div itemprop="about">Stem cells (Dayton, Ohio)</div> <div itemprop="author">Suga H,Rennert RC,Rodrigues M,Sorkin M,Glotzbach JP,Januszyk M,Fujiwara T,Longaker MT,Gurtner GC</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Thu May 01 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24935925"> <div itemprop="name">Tryptophan catabolism restricts IFN-γ-expressing neutrophils and Clostridium difficile immunopathology.</div> </a> <div itemprop="about">Journal of immunology (Baltimore, Md. : 1950)</div> <div itemprop="author">El-Zaatari M,Chang YM,Zhang M,Franz M,Shreiner A,McDermott AJ,van der Sluijs KF,Lutter R,Grasberger H,Kamada N,Young VB,Huffnagle GB,Kao JY</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Tue Jul 15 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24806994"> <div itemprop="name">CCR2 deficiency impairs macrophage infiltration and improves cognitive function after traumatic brain injury.</div> </a> <div itemprop="about">Journal of neurotrauma</div> <div itemprop="author">Hsieh CL,Niemi EC,Wang SH,Lee CC,Bingham D,Zhang J,Cozen ML,Charo I,Huang EJ,Liu J,Nakamura MC</div> <div itemprop="description">15-0112 was used in Flow cytometry/Cell sorting to suggest that therapeutic blockade of CCR2-dependent responses may improve outcomes following traumatic brain injury (TBI).</div> <div itemprodp="datePublished">Wed Oct 15 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/25042352"> <div itemprop="name">Increased expression of stress inducible protein 1 in glioma-associated microglia/macrophages.</div> </a> <div itemprop="about">Journal of neuroimmunology</div> <div itemprop="author">Carvalho da Fonseca AC,Wang H,Fan H,Chen X,Zhang I,Zhang L,Lima FR,Badie B</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Mon Sep 15 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/25348003"> <div itemprop="name">Metastasis is regulated via microRNA-200/ZEB1 axis control of tumour cell PD-L1 expression and intratumoral immunosuppression.</div> </a> <div itemprop="about">Nature communications</div> <div itemprop="author">Chen L,Gibbons DL,Goswami S,Cortez MA,Ahn YH,Byers LA,Zhang X,Yi X,Dwyer D,Lin W,Diao L,Wang J,Roybal J,Patel M,Ungewiss C,Peng D,Antonia S,Mediavilla-Varela M,Robertson G,Suraokar M,Welsh JW,Erez B,Wistuba II,Chen L,Peng D,Wang S,Ullrich SE,Heymach JV,Kurie JM,Qin FX</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Tue Oct 28 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/25198549"> <div itemprop="name">Amniotic fluid stem cells prevent follicle atresia and rescue fertility of mice with premature ovarian failure induced by chemotherapy.</div> </a> <div itemprop="about">PloS one</div> <div itemprop="author">Xiao GY,Liu IH,Cheng CC,Chang CC,Lee YH,Cheng WT,Wu SC</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Thu May 28 00:00:00 EDT 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24965046"> <div itemprop="name">Anti-tumor innate immunity activated by intermittent metronomic cyclophosphamide treatment of 9L brain tumor xenografts is preserved by anti-angiogenic drugs that spare VEGF receptor 2.</div> </a> <div itemprop="about">Molecular cancer</div> <div itemprop="author">Doloff JC,Chen CS,Waxman DJ</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Thu Jun 26 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24465940"> <div itemprop="name">Influenza virus-induced lung inflammation was modulated by cigarette smoke exposure in mice.</div> </a> <div itemprop="about">PloS one</div> <div itemprop="author">Han Y,Ling MT,Mao H,Zheng J,Liu M,Lam KT,Liu Y,Tu W,Lau YL</div> <div itemprop="description">15-0112 was used in Flow cytometry/Cell sorting to investigate the effect of cigarette smoke on pandemic H1N1 or H9N2 virus infection, showing that virus-induced lung inflammation was modulated by cigarette smoke exposure.</div> <div itemprodp="datePublished">Wed Oct 29 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/25259859"> <div itemprop="name">Leukocyte population dynamics and detection of IL-9 as a major cytokine at the mouse fetal-maternal interface.</div> </a> <div itemprop="about">PloS one</div> <div itemprop="author">Habbeddine M,Verbeke P,Karaz S,Bobé P,Kanellopoulos-Langevin C</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Wed Jun 10 00:00:00 EDT 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/25310682"> <div itemprop="name">P2X7 receptor modulates inflammatory and functional pulmonary changes induced by silica.</div> </a> <div itemprop="about">PloS one</div> <div itemprop="author">Monção-Ribeiro LC,Faffe DS,Santana PT,Vieira FS,da Graça CL,Marques-da-Silva C,Machado MN,Caruso-Neves C,Zin WA,Borojevic R,Takiya CM,Coutinho-Silva R</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Thu Sep 17 00:00:00 EDT 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24366868"> <div itemprop="name">The nucleotide-binding leucine-rich repeat (NLR) family member NLRX1 mediates protection against experimental autoimmune encephalomyelitis and represses macrophage/microglia-induced inflammation.</div> </a> <div itemprop="about">The Journal of biological chemistry</div> <div itemprop="author">Eitas TK,Chou WC,Wen H,Gris D,Robbins GR,Brickey J,Oyama Y,Ting JP</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Fri Feb 14 00:00:00 EST 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24366868"> <div itemprop="name">The nucleotide-binding leucine-rich repeat (NLR) family member NLRX1 mediates protection against experimental autoimmune encephalomyelitis and represses macrophage/microglia-induced inflammation.</div> </a> <div itemprop="about">The Journal of biological chemistry</div> <div itemprop="author">Eitas TK,Chou WC,Wen H,Gris D,Robbins GR,Brickey J,Oyama Y,Ting JP</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Fri Feb 14 00:00:00 EST 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23416702"> <div itemprop="name">Lysine-specific demethylase 1 is a therapeutic target for fetal hemoglobin induction.</div> </a> <div itemprop="about">Nature medicine</div> <div itemprop="author">Shi L,Cui S,Engel JD,Tanabe O</div> <div itemprop="description">15-0112 was used in Flow cytometry/Cell sorting to examine the effect of lysine-specific demethylase 1 inhibition on the expression of foetal γ-globin.</div> <div itemprodp="datePublished">Fri Mar 01 00:00:00 EST 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23389440"> <div itemprop="name">FOXO3A directs a protective autophagy program in haematopoietic stem cells.</div> </a> <div itemprop="about">Nature</div> <div itemprop="author">Warr MR,Binnewies M,Flach J,Reynaud D,Garg T,Malhotra R,Debnath J,Passegué E</div> <div itemprop="description">15-0112 was used in Flow cytometry/Cell sorting to show how FOXO3A directs a protective autophagy program in haematopoietic stem cells.</div> <div itemprodp="datePublished">Thu Feb 21 00:00:00 EST 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23396050"> <div itemprop="name">miR-126 and miR-126* repress recruitment of mesenchymal stem cells and inflammatory monocytes to inhibit breast cancer metastasis.</div> </a> <div itemprop="about">Nature cell biology</div> <div itemprop="author">Zhang Y,Yang P,Sun T,Li D,Xu X,Rui Y,Li C,Chong M,Ibrahim T,Mercatali L,Amadori D,Lu X,Xie D,Li QJ,Wang XF</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Fri Mar 01 00:00:00 EST 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23719262"> <div itemprop="name">S100B promotes glioma growth through chemoattraction of myeloid-derived macrophages.</div> </a> <div itemprop="about">Clinical cancer research : an official journal of the American Association for Cancer Research</div> <div itemprop="author">Wang H,Zhang L,Zhang IY,Chen X,Da Fonseca A,Wu S,Ren H,Badie S,Sadeghi S,Ouyang M,Warden CD,Badie B</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Mon Jul 15 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24176643"> <div itemprop="name">A network of interactions enables CCM3 and STK24 to coordinate UNC13D-driven vesicle exocytosis in neutrophils.</div> </a> <div itemprop="about">Developmental cell</div> <div itemprop="author">Zhang Y,Tang W,Zhang H,Niu X,Xu Y,Zhang J,Gao K,Pan W,Boggon TJ,Toomre D,Min W,Wu D</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Mon Oct 28 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23630120"> <div itemprop="name">Traumatic brain injury induces macrophage subsets in the brain.</div> </a> <div itemprop="about">European journal of immunology</div> <div itemprop="author">Hsieh CL,Kim CC,Ryba BE,Niemi EC,Bando JK,Locksley RM,Liu J,Nakamura MC,Seaman WE</div> <div itemprop="description">15-0112 was used in Flow cytometry/Cell sorting to better understand the mechanisms involved in the innate inflammatory responses to brain injury.</div> <div itemprodp="datePublished">Thu Aug 01 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23248263"> <div itemprop="name">Coactivator-associated arginine methyltransferase 1 regulates fetal hematopoiesis and thymocyte development.</div> </a> <div itemprop="about">Journal of immunology (Baltimore, Md. : 1950)</div> <div itemprop="author">Li J,Zhao Z,Carter C,Ehrlich LI,Bedford MT,Richie ER</div> <div itemprop="description">15-0112 was used in Flow cytometry/Cell sorting to demonstrate how CARM1 is a key epigenetic regulator of hematopoiesis that affects multiple lineages at various stages of differentiation.</div> <div itemprodp="datePublished">Tue Jan 15 00:00:00 EST 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23682015"> <div itemprop="name">Migration of bone marrow-derived cells into the central nervous system in models of neurodegeneration.</div> </a> <div itemprop="about">The Journal of comparative neurology</div> <div itemprop="author">Lampron A,Pimentel-Coelho PM,Rivest S</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Sun Dec 01 00:00:00 EST 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23720750"> <div itemprop="name">The cardioprotective protein apolipoprotein A1 promotes potent anti-tumorigenic effects.</div> </a> <div itemprop="about">The Journal of biological chemistry</div> <div itemprop="author">Zamanian-Daryoush M,Lindner D,Tallant TC,Wang Z,Buffa J,Klipfell E,Parker Y,Hatala D,Parsons-Wingerter P,Rayman P,Yusufishaq MSS,Fisher EA,Smith JD,Finke J,DiDonato JA,Hazen SL</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Fri Jul 19 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23409194"> <div itemprop="name">Partial depletion of regulatory T cells does not influence the inflammation caused by high dose hemi-body irradiation.</div> </a> <div itemprop="about">PloS one</div> <div itemprop="author">Ma S,Richardson JA,Bitmansour A,Solberg TD,Pidikiti R,Song K,Stojadinovic S,Vitetta ES,Meyer JJ</div> <div itemprop="description">15-0112 was used in Flow cytometry/Cell sorting to investigate the effects of partial depletion of regulatory T cells alongside ionizing radiation on inflammation and tissue injury in mice.</div> <div itemprodp="datePublished">Mon Jul 29 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24279871"> <div itemprop="name">G-CSF/anti-G-CSF antibody complexes drive the potent recovery and expansion of CD11b+Gr-1+ myeloid cells without compromising CD8+ T cell immune responses.</div> </a> <div itemprop="about">Journal of hematology & oncology</div> <div itemprop="author">Rubinstein MP,Salem ML,Doedens AL,Moore CJ,Chiuzan C,Rivell GL,Cole DJ,Goldrath AW</div> <div itemprop="description">15-0112 was used in Flow cytometry/Cell sorting to evaluate whether the biological activity of G-CSF can be improved by pre-association with anti-G-CSF monoclonal antibodies prior to injection.</div> <div itemprodp="datePublished">Tue Oct 01 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23264627"> <div itemprop="name">Identification of the low density lipoprotein (LDL) receptor-related protein-1 interactome in central nervous system myelin suggests a role in the clearance of necrotic cell debris.</div> </a> <div itemprop="about">The Journal of biological chemistry</div> <div itemprop="author">Fernandez-Castaneda A,Arandjelovic S,Stiles TL,Schlobach RK,Mowen KA,Gonias SL,Gaultier A</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Fri Feb 15 00:00:00 EST 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22919031"> <div itemprop="name">Endothelial cells provide an instructive niche for the differentiation and functional polarization of M2-like macrophages.</div> </a> <div itemprop="about">Blood</div> <div itemprop="author">He H,Xu J,Warren CM,Duan D,Li X,Wu L,Iruela-Arispe ML</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Thu Oct 11 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22996659"> <div itemprop="name">Cis-element mutated in GATA2-dependent immunodeficiency governs hematopoiesis and vascular integrity.</div> </a> <div itemprop="about">The Journal of clinical investigation</div> <div itemprop="author">Johnson KD,Hsu AP,Ryu MJ,Wang J,Gao X,Boyer ME,Liu Y,Lee Y,Calvo KR,Keles S,Zhang J,Holland SM,Bresnick EH</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Mon Oct 01 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22170060"> <div itemprop="name">Metalloproteinase-mediated Shedding of Integrin β2 promotes macrophage efflux from inflammatory sites.</div> </a> <div itemprop="about">The Journal of biological chemistry</div> <div itemprop="author">Gomez IG,Tang J,Wilson CL,Yan W,Heinecke JW,Harlan JM,Raines EW</div> <div itemprop="description">15-0112 was used in an ELISA assay to investigate peritonitis-elevated levels of integrin β2 at times when macrophages are exiting the peritoneum.</div> <div itemprodp="datePublished">Fri Feb 10 00:00:00 EST 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22633413"> <div itemprop="name">A nonpeptidic cathepsin S activity-based probe for noninvasive optical imaging of tumor-associated macrophages.</div> </a> <div itemprop="about">Chemistry & biology</div> <div itemprop="author">Verdoes M,Edgington LE,Scheeren FA,Leyva M,Blum G,Weiskopf K,Bachmann MH,Ellman JA,Bogyo M</div> <div itemprop="description">15-0112 was used in Flow cytometry/Cell sorting to study how BMV083 may be a valuable in vivo reporter for tumor-associated macrophages.</div> <div itemprodp="datePublished">Fri May 25 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22952867"> <div itemprop="name">Induction of histiocytic sarcoma in mouse skeletal muscle.</div> </a> <div itemprop="about">PloS one</div> <div itemprop="author">Liu J,Hettmer S,Milsom MD,Hofmann I,Hua F,Miller C,Bronson RT,Wagers AJ</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Thu Feb 07 00:00:00 EST 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21987785"> <div itemprop="name">Requirement for complement in antibody responses is not explained by the classic pathway activator IgM.</div> </a> <div itemprop="about">Proceedings of the National Academy of Sciences of the United States of America</div> <div itemprop="author">Rutemark C,Alicot E,Bergman A,Ma M,Getahun A,Ellmerich S,Carroll MC,Heyman B</div> <div itemprop="description">15-0112 was used in Flow cytometry/Cell sorting to investigate the role of the classical pathway activator IgM in complement activated antibody responses.</div> <div itemprodp="datePublished">Tue Oct 25 00:00:00 EDT 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20688058"> <div itemprop="name">Plasmodium falciparum: differential merozoite dose requirements for maximal production of various inflammatory cytokines.</div> </a> <div itemprop="about">Experimental parasitology</div> <div itemprop="author">Wu X,Gowda NM,Gowda DC</div> <div itemprop="description">15-0112 was used in Flow cytometry/Cell sorting to investigate differential merozoite dose requirements for maximal production of various inflammatory cytokines in Plasmodium falciparum.</div> <div itemprodp="datePublished">Sat Jan 01 00:00:00 EST 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21779371"> <div itemprop="name">PAD4-mediated neutrophil extracellular trap formation is not required for immunity against influenza infection.</div> </a> <div itemprop="about">PloS one</div> <div itemprop="author">Hemmers S,Teijaro JR,Arandjelovic S,Mowen KA</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Tue Nov 15 00:00:00 EST 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21731674"> <div itemprop="name">An information theoretic, microfluidic-based single cell analysis permits identification of subpopulations among putatively homogeneous stem cells.</div> </a> <div itemprop="about">PloS one</div> <div itemprop="author">Glotzbach JP,Januszyk M,Vial IN,Wong VW,Gelbard A,Kalisky T,Thangarajah H,Longaker MT,Quake SR,Chu G,Gurtner GC</div> <div itemprop="description">15-0112 was used in Flow cytometry/Cell sorting to develop a novel method to characterize and predict transcriptional programs across individual homogeneous stem cells.</div> <div itemprodp="datePublished">Wed Nov 02 00:00:00 EDT 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20042501"> <div itemprop="name">Measles virus infection of alveolar macrophages and dendritic cells precedes spread to lymphatic organs in transgenic mice expressing human signaling lymphocytic activation molecule (SLAM, CD150).</div> </a> <div itemprop="about">Journal of virology</div> <div itemprop="author">Ferreira CS,Frenzke M,Leonard VH,Welstead GG,Richardson CD,Cattaneo R</div> <div itemprop="description">15-0112 was used in Flow cytometry/Cell sorting to identify the cells that support primary measles infection before systemic spread.</div> <div itemprodp="datePublished">Mon Mar 01 00:00:00 EST 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20303345"> <div itemprop="name">Additive and global functions of HoxA cluster genes in mesoderm derivatives.</div> </a> <div itemprop="about">Developmental biology</div> <div itemprop="author">Di-Poï N,Koch U,Radtke F,Duboule D</div> <div itemprop="description">15-0112 was used in Flow cytometry/Cell sorting to report that mutant mice lacking the entire HoxA cluster in mesodermal lineages display the expected spectrum of postnatal respiratory, cardiac and urogenital defects, previously reported for single gene mutations.</div> <div itemprodp="datePublished">Sat May 15 00:00:00 EDT 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20109461"> <div itemprop="name">Stromal cell independent B cell development in vitro: generation and recovery of autoreactive clones.</div> </a> <div itemprop="about">Journal of immunological methods</div> <div itemprop="author">Holl TM,Haynes BF,Kelsoe G</div> <div itemprop="description">15-0112 was used in Flow cytometry/Cell sorting to describe a stromal cell independent culture system that efficiently supports pro-B cell to IgM+ B cell development with near normal levels of IgH and Igkappa diversity.</div> <div itemprodp="datePublished">Wed Mar 31 00:00:00 EDT 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20506316"> <div itemprop="name">Deficiency of CXCR2, but not other chemokine receptors, attenuates autoantibody-mediated arthritis in a murine model.</div> </a> <div itemprop="about">Arthritis and rheumatism</div> <div itemprop="author">Jacobs JP,Ortiz-Lopez A,Campbell JJ,Gerard CJ,Mathis D,Benoist C</div> <div itemprop="description">15-0112 was used in Flow cytometry/Cell sorting to investigate chemokines and their receptors in the effector phase of arthritis.</div> <div itemprodp="datePublished">Thu Jul 01 00:00:00 EDT 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/19699173"> <div itemprop="name">Dynamics of T cell, antigen-presenting cell, and pathogen interactions during recall responses in the lymph node.</div> </a> <div itemprop="about">Immunity</div> <div itemprop="author">Chtanova T,Han SJ,Schaeffer M,van Dooren GG,Herzmark P,Striepen B,Robey EA</div> <div itemprop="description">15-0112 was used in Flow cytometry/Cell sorting to provide insight into cellular interactions during recall responses and suggest a mechanism of pathogen subversion of the immune response.</div> <div itemprodp="datePublished">Fri Aug 21 00:00:00 EDT 2009</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/19497282"> <div itemprop="name">Wnt7a activates the planar cell polarity pathway to drive the symmetric expansion of satellite stem cells.</div> </a> <div itemprop="about">Cell stem cell</div> <div itemprop="author">Le Grand F,Jones AE,Seale V,Scimè A,Rudnicki MA</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Fri Jun 05 00:00:00 EDT 2009</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/19414791"> <div itemprop="name">Dynamic imaging of T cell-parasite interactions in the brains of mice chronically infected with Toxoplasma gondii.</div> </a> <div itemprop="about">Journal of immunology (Baltimore, Md. : 1950)</div> <div itemprop="author">Schaeffer M,Han SJ,Chtanova T,van Dooren GG,Herzmark P,Chen Y,Roysam B,Striepen B,Robey EA</div> <div itemprop="description">15-0112 was used in Flow cytometry/Cell sorting to directly observe the dynamics of T cell-parasite interactions within living tissue and further understand immune responses to persistent pathogens in the brain.</div> <div itemprodp="datePublished">Fri May 15 00:00:00 EDT 2009</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/18718768"> <div itemprop="name">Dynamics of neutrophil migration in lymph nodes during infection.</div> </a> <div itemprop="about">Immunity</div> <div itemprop="author">Chtanova T,Schaeffer M,Han SJ,van Dooren GG,Nollmann M,Herzmark P,Chan SW,Satija H,Camfield K,Aaron H,Striepen B,Robey EA</div> <div itemprop="description">15-0112 was used in Flow cytometry/Cell sorting to provide insight into the cellular mechanisms underlying neutrophil swarming and suggest new roles for neutrophils in shaping immune responses.</div> <div itemprodp="datePublished">Fri Sep 19 00:00:00 EDT 2008</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/18728019"> <div itemprop="name">Phospholipase Cgamma2 mediates RANKL-stimulated lymph node organogenesis and osteoclastogenesis.</div> </a> <div itemprop="about">The Journal of biological chemistry</div> <div itemprop="author">Chen Y,Wang X,Di L,Fu G,Chen Y,Bai L,Liu J,Feng X,McDonald JM,Michalek S,He Y,Yu M,Fu YX,Wen R,Wu H,Wang D</div> <div itemprop="description">Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry</div> <div itemprodp="datePublished">Fri Oct 24 00:00:00 EDT 2008</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/18667426"> <div itemprop="name">Stable form of JAB1 enhances proliferation and maintenance of hematopoietic progenitors.</div> </a> <div itemprop="about">The Journal of biological chemistry</div> <div itemprop="author">Mori M,Yoneda-Kato N,Yoshida A,Kato JY</div> <div itemprop="description">15-0112 was used in Flow cytometry/Cell sorting to investigate how the expression and function of JAB1 are critical for the proliferation and maintenance of hematopoietic progenitors.</div> <div itemprodp="datePublished">Fri Oct 24 00:00:00 EDT 2008</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/17032926"> <div itemprop="name">The impact of altered p53 dosage on hematopoietic stem cell dynamics during aging.</div> </a> <div itemprop="about">Blood</div> <div itemprop="author">Dumble M,Moore L,Chambers SM,Geiger H,Van Zant G,Goodell MA,Donehower LA</div> <div itemprop="description">15-0112 was used in Flow cytometry/Cell sorting to study how altering p53 dosage during ageing impacts hematopoietic stem cell dynamics.</div> <div itemprodp="datePublished">Thu Feb 15 00:00:00 EST 2007</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/17948263"> <div itemprop="name">Immature hematopoietic cells display selective requirements for adhesion- and degranulation-promoting adaptor protein in development and homeostatsis.</div> </a> <div itemprop="about">European journal of immunology</div> <div itemprop="author">Dluzniewska J,Zou L,Harmon IR,Ellingson MT,Peterson EJ</div> <div itemprop="description">15-0112-82 was used in Flow Cytometry to highlight the dynamic regulation of ADAP during T cell maturation and document expression patterns that suggest a possible role for ADAP in development of non-T hematopoietic lineages.</div> <div itemprodp="datePublished">Thu Nov 01 00:00:00 EDT 2007</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/17090683"> <div itemprop="name">Developmental switch of mouse hematopoietic stem cells from fetal to adult type occurs in bone marrow after birth.</div> </a> <div itemprop="about">Proceedings of the National Academy of Sciences of the United States of America</div> <div itemprop="author">Kikuchi K,Kondo M</div> <div itemprop="description">15-0112 was used in Flow cytometry/Cell sorting to demonstrate how foetal haematopoietic stem cells may acquire adult characteristics between 1 and 2 weeks after birth in mouse bone marrow.</div> <div itemprodp="datePublished">Tue Nov 21 00:00:00 EST 2006</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/14718516"> <div itemprop="name">Beta-catenin is dispensable for hematopoiesis and lymphopoiesis.</div> </a> <div itemprop="about">The Journal of experimental medicine</div> <div itemprop="author">Cobas M,Wilson A,Ernst B,Mancini SJ,MacDonald HR,Kemler R,Radtke F</div> <div itemprop="description">15-0112 was used in Flow cytometry/Cell sorting to investigate an essential role for beta-catenin during hematopoiesis and lymphopoiesis.</div> <div itemprodp="datePublished">Mon Jan 19 00:00:00 EST 2004</div> </div> </noscript> </div> <div class="border-bottom"></div> <div class="product-bioinformatics-details"> <div class="container"> <h2 class="pdp-sub-heading">Bioinformatics</h2> <div class="row"> <div class="large-span-6 medium-span-12 small-span-12"> <div class="bioinformatics-wrapper"> <p class="bioinformatics-detail-section" id="proteinContent"> <strong>Protein Aliases:</strong> CD11 antigen-like family member B; CD11B (p170); cell surface glycoprotein MAC-1 alpha subunit; cell surface glycoprotein MAC-1 subunit alpha; complement component receptor 3 alpha-a; complement receptor type 3; CR-3 alpha chain; integrin alpha-M; leukocyte adhesion receptor MO1; Mac-1 alpha; Mac-1 alpha (Mac1A); macrophage antigen alpha; MGC117044 </p> <p class="view-buttons" id="ptnViewBtn" ng-class="$ctrl.bioContentLines('proteinContent', 'ptnViewBtn')"> <a id="proteinViewMoreBtn" ng-click="$ctrl.bioContentViewMore('proteinViewMoreBtn', 'proteinViewLessBtn', 'proteinContent')"> View more </a> <a id="proteinViewLessBtn" ng-click="$ctrl.bioContentViewLess('proteinViewLessBtn', 'proteinViewMoreBtn', 'proteinContent')"> View less </a> </p> </div> <div class="bioinformatics-wrapper"> <p class="bioinformatics-detail-section" id="geneContent"> <strong>Gene Aliases:</strong> Cd11b; CD11b/CD18; CR3; CR3A; F730045J24Rik; Ly-40; Mac-1; Mac-1a; MAC1 </p> <p class="view-buttons" id="geneViewBtn" ng-class="$ctrl.bioContentLines('geneContent', 'geneViewBtn')"> <a id="geneViewMoreBtn" ng-click="$ctrl.bioContentViewMore('geneViewMoreBtn', 'geneViewLessBtn', 'geneContent')"> View more </a> <a id="geneViewLessBtn" ng-click="$ctrl.bioContentViewLess('geneViewLessBtn', 'geneViewMoreBtn', 'geneContent')"> View less </a> </p> </div> <div class="bioinformatics-wrapper"> <p class="bioinformatics-detail-section" id="entrezContent"> <strong>Entrez Gene ID:</strong> <a href="http://www.ncbi.nlm.nih.gov/gene?term=16409" target="_blank">(Mouse) 16409</a> </p> <p class="view-buttons" id="etzViewBtn" ng-class="$ctrl.bioContentLines('entrezContent', 'etzViewBtn')"> <a id="entrezViewMoreBtn" ng-click="$ctrl.bioContentViewMore('entrezViewMoreBtn', 'entrezViewLessBtn', 'entrezContent')"> View more </a> <a id="entrezViewLessBtn" ng-click="$ctrl.bioContentViewLess('entrezViewLessBtn', 'entrezViewMoreBtn', 'entrezContent')"> View less </a> </p> </div> </div> <div class="large-span-6 medium-span-12 small-span-12"> <div class="accordion" id="accordion-bioinformatics"> <div class="accordion-group"> <div class="accordion-heading"> <a class="accordion-toggle" data-toggle="collapse" data-parent="#accordion2" target="_self" href="#collapseOne"> Function(s) </a> </div> <div id="collapseOne" class="accordion-body collapse"> <div class="accordion-inner"> <a class="icon" href="/antibody/primary/panther/opsonin binding"> opsonin binding </a> <a class="icon" href="/antibody/primary/panther/glycoprotein binding"> glycoprotein binding </a> <a class="icon" href="/antibody/primary/panther/heparin binding"> heparin binding </a> <a class="icon" href="/antibody/primary/panther/heparan sulfate proteoglycan binding"> heparan sulfate proteoglycan binding </a> <a class="icon" href="/antibody/primary/panther/metal ion binding"> metal ion binding </a> <a class="icon" href="/antibody/primary/panther/protein heterodimerization activity"> protein heterodimerization activity </a> <a class="icon" href="/antibody/primary/panther/integrin"> integrin </a> </div> </div> </div> <div class="accordion-group"> <div class="accordion-heading"> <a class="accordion-toggle" data-toggle="collapse" data-parent="#accordion2" target="_self" href="#collapseTwo"> Process(es) </a> </div> <div id="collapseTwo" class="accordion-body collapse"> <div class="accordion-inner"> <a class="icon" href="/antibody/primary/panther/leukocyte migration involved in inflammatory response"> leukocyte migration involved in inflammatory response </a> <a class="icon" href="/antibody/primary/panther/cell adhesion"> cell adhesion </a> <a class="icon" href="/antibody/primary/panther/leukocyte cell-cell adhesion"> leukocyte cell-cell adhesion </a> <a class="icon" href="/antibody/primary/panther/integrin-mediated signaling pathway"> integrin-mediated signaling pathway </a> <a class="icon" href="/antibody/primary/panther/microglia development"> microglia development </a> <a class="icon" href="/antibody/primary/panther/single organismal cell-cell adhesion"> single organismal cell-cell adhesion </a> <a class="icon" href="/antibody/primary/panther/neutrophil chemotaxis"> neutrophil chemotaxis </a> <a class="icon" href="/antibody/primary/panther/cellular extravasation"> cellular extravasation </a> <a class="icon" href="/antibody/primary/panther/activated T cell proliferation"> activated T cell proliferation </a> </div> </div> </div> </div> </div> </div> </div> </div> <div class="recommended-products border-bottom hidden">  It has to be done as per old AB suggested Products section. </div> <script type="text/javascript" src="/order/genome-database/assets/core/js/magellanCore.js?version=Local&time=20240917&build-time=2024-11-22T02:34:20+0000"></script> <script type="text/javascript"> $m.addPerformanceMark('abPDPScripts:loadBegin'); </script> <script type="text/javascript" src="/order/genome-database/assets/js/shared-module/dist/angular108-document-scripts.js?version=Local&time=20240917&build-time=2024-11-22T02:34:20+0000"></script> <script type="text/javascript" src="/order/genome-database/assets/js/shared-module/dist/pdp-combined-scripts.js?version=Local&time=20240917&build-time=2024-11-22T02:34:20+0000"></script> <script type="text/javascript" src="/order/genome-database/assets/js/shared-module/dist/combined-vendor.js?version=Local&time=20240917&build-time=2024-11-22T02:34:20+0000"></script> <script defer type="text/javascript" src="/order/genome-database/assets/core/dist/angular/gallery-module/gallery-module.js?version=Local&time=20240917&build-time=2024-11-22T02:34:20+0000"></script> <script type="text/javascript" src="/order/genome-database/assets/js/angular/dist/pdp/common.pdp.dist.js?version=Local&time=20240917&build-time=2024-11-22T02:34:20+0000"></script> <script type="text/javascript" src="/order/genome-database/assets/js/angular/dist/pdp/antibody.pdp.dist.js?version=Local&time=20240917&build-time=2024-11-22T02:34:20+0000"></script> <script defer type="text/javascript" src="/order/genome-database/assets/js/shared-module/dist/pdp/template-cache-cmrc-card-antibody.js?version=Local&time=20240917&build-time=2024-11-22T02:34:20+0000"></script> <script defer type="text/javascript" src="/order/genome-database/assets/js/shared-module/dist/pdp/template-cache-hero.js?version=Local&time=20240917&build-time=2024-11-22T02:34:20+0000"></script> <script defer type="text/javascript" src="/order/genome-database/assets/js/shared-module/dist/pdp/template-cache-reference-section.js?version=Local&time=20240917&build-time=2024-11-22T02:34:20+0000"></script> <script type="text/javascript"> $m.addPerformanceMark('abPDPScripts:loadEnd'); $m.addPerformanceMeasure('abPDPScripts:loadTime' , 'abPDPScripts:loadBegin', 'abPDPScripts:loadEnd'); </script> </div> <script> if (typeof window.$mangular === 'undefined' || !window.$mangular) { window.$mangular = {}; } window.$mangular.referenceCount = 289; window.$mangular.publishedFiguresCount = 98; window.$mangular.productId = '15-0112-82'; window.$mangular.citationJson = {"citationApplications":[{"applicationAbbreviation":"ICC/IF","citations":[{"title":"Tracking the elusive fibrocyte: identification and characterization of collagen-producing hematopoietic lineage cells during murine wound healing.","summary":"Published figure using CD11b monoclonal antibody (Product # 15-0112-82) in Flow Cytometry","authors":"Suga H,Rennert RC,Rodrigues M,Sorkin M,Glotzbach JP,Januszyk M,Fujiwara T,Longaker MT,Gurtner GC","literatureId":"24446236","journal":"Stem cells (Dayton, Ohio)","volume":"32","pageNumber":"1347","publishedDate":"May 1, 2014, 4:00:00 AM","url":"http://dx.doi.org/10.1002/stem.1648","benchSci":false,"imageURL":"https://www.thermofisher.com/antibody/images/250/null?time\u003d20240507","journalAbbr":"Stem Cells","sortOrder":243,"species":["Mouse"],"speciesDilutionMap":{"Mouse":"Not Cited"},"abbreviationToNameMap":{"ICC/IF":"Immunocytochemistry","Flow":"Flow Cytometry"},"newSpeciesDilutionMap":{"Mouse~Flow~Not Cited":""}},{"title":"Pluripotency factors functionally premark cell-type-restricted enhancers in ES cells.","summary":"15-0112 was used in Immunocytochemistry-Immunofluorescence to examine the hierarchical and obligate premarking of cell-type-restricted enhancers in embryonic stem cells.","authors":"Kim HS,Tan Y,Ma W,Merkurjev D,Destici E,Ma Q,Suter T,Ohgi K,Friedman M,Skowronska-Krawczyk D,Rosenfeld MG","literatureId":"29670286","journal":"Nature","volume":"556","pageNumber":"510","publishedDate":"Apr 1, 2018, 4:00:00 AM","url":"http://dx.doi.org/10.1038/s41586-018-0048-8","benchSci":false,"imageURL":"https://www.thermofisher.com/antibody/images/250/null?time\u003d20240507","journalAbbr":"Nature","sortOrder":113,"species":["Mouse"],"speciesDilutionMap":{"Mouse":"Not Cited"},"abbreviationToNameMap":{"ICC/IF":"Immunocytochemistry"},"newSpeciesDilutionMap":{"Mouse~ICC/IF~Not Cited":""}}],"citationsCount":2,"speciesList":["Mouse"],"journals":["Stem Cells","Nature"],"speciesMap":{"Mouse":2},"journalsMap":{"Stem Cells":1,"Nature":1},"sortedMap":{}},{"applicationAbbreviation":"Flow","citations":[],"citationsCount":287,"speciesList":["Human","Mouse","Fish"],"journals":["NPJ Vaccines","Brain","Mol Med Rep","Nat Commun","J Transl Med","Alcohol Clin Exp Res","Dis Model Mech","Blood","Stem Cells","Nat Neurosci","Nat Med","Arterioscler Thromb Vasc Biol","J Autoimmun","Development","Am J Blood Res","Nat Cell Biol","Acta Ophthalmol","PLoS One","J Cell Biochem","Dev Cell","RNA Biol","Dev Biol","Aging (Albany NY)","J Am Soc Nephrol","J Neuroinflammation","J Ginseng Res","Biology (Basel)","J Appl Toxicol","J Cereb Blood Flow Metab","Bioact Mater","Redox Biol","Mater Today Bio","Elife","PLoS Genet","Shock","J Immunol","Anticancer Drugs","Hepatology","J Leukoc Biol","Physiol Rep","Iran J Basic Med Sci","JCI Insight","Oncoimmunology","Chonnam Med J","Biomed Res Int","Adv Mater","iScience","Nature","Stem Cell Reports","J Clin Cell Immunol","Front Physiol","J Immunol Methods","Br J Pharmacol","Cancer Cell","J Clin Invest","Adv Sci (Weinh)","Nanomicro Lett","PLoS Biol","Cell Stem Cell","J Cell Physiol","Nat Metab","Commun Biol","Proc Natl Acad Sci U S A","Int J Nanomedicine","J Bone Miner Res","Breast Cancer Res","Sci Adv","Exp Mol Med","Oncotarget","Immunity","Int J Mol Med","Stem Cells Int","Cell","Stem Cells Transl Med","Cancer Res","Immunohorizons","Cancers (Basel)","Acta Pharm Sin B","PLoS Negl Trop Dis","STAR Protoc","Cell Host Microbe","Stem Cell Res Ther","Clin Cancer Res","Sci Rep","Arthritis Rheum","Biomedicines","Endocrinology","Exp Parasitol","EMBO J","Cell Mol Immunol","Int J Mol Sci","Nat Immunol","J Exp Med","Chem Biol","Cell Rep","Cell Microbiol","Exp Ther Med","Cell Death Dis","J Virol","J Neuroimmunol","Immunology","J Immunother Cancer","Eur J Immunol","J Comp Neurol","J Hematol Oncol","Mol Med","Tissue Eng Part A","Front Immunol","J Neurotrauma","Mucosal Immunol","Front Pharmacol","Theranostics","Cells","J Reprod Dev","Pain Res Manag","Am J Physiol Gastrointest Liver Physiol","PLoS Pathog","Cell Mol Gastroenterol Hepatol","J Biol Chem","Glia","Mol Cancer","Part Fibre Toxicol"],"speciesMap":{"Human":4,"Mouse":66,"Fish":1},"journalsMap":{"NPJ Vaccines":1,"Brain":1,"Mol Med Rep":4,"Nat Commun":24,"J Transl Med":1,"Alcohol Clin Exp Res":1,"Dis Model Mech":1,"Blood":3,"Stem Cells":1,"Nat Neurosci":3,"Nat Med":3,"Arterioscler Thromb Vasc Biol":1,"J Autoimmun":1,"Development":1,"Am J Blood Res":1,"Nat Cell Biol":1,"Acta Ophthalmol":1,"PLoS One":14,"J Cell Biochem":2,"Dev Cell":1,"RNA Biol":1,"Dev Biol":1,"Aging (Albany NY)":3,"J Am Soc Nephrol":2,"J Neuroinflammation":3,"J Ginseng Res":1,"Biology (Basel)":1,"J Appl Toxicol":1,"J Cereb Blood Flow Metab":1,"Bioact Mater":1,"Redox Biol":1,"Mater Today Bio":1,"Elife":1,"PLoS Genet":1,"Shock":1,"J Immunol":5,"Anticancer Drugs":1,"Hepatology":1,"J Leukoc Biol":2,"Physiol Rep":1,"Iran J Basic Med Sci":1,"JCI Insight":8,"Oncoimmunology":4,"Chonnam Med J":1,"Biomed Res Int":2,"Adv Mater":1,"iScience":1,"Nature":7,"Stem Cell Reports":2,"J Clin Cell Immunol":1,"Front Physiol":1,"J Immunol Methods":1,"Br J Pharmacol":3,"Cancer Cell":1,"J Clin Invest":9,"Adv Sci (Weinh)":2,"Nanomicro Lett":1,"PLoS Biol":1,"Cell Stem Cell":2,"J Cell Physiol":2,"Nat Metab":1,"Commun Biol":1,"Proc Natl Acad Sci U S A":4,"Int J Nanomedicine":1,"J Bone Miner Res":2,"Breast Cancer Res":1,"Sci Adv":1,"Exp Mol Med":1,"Oncotarget":5,"Immunity":5,"Int J Mol Med":1,"Stem Cells Int":1,"Cell":5,"Stem Cells Transl Med":1,"Cancer Res":1,"Immunohorizons":1,"Cancers (Basel)":3,"Acta Pharm Sin B":1,"PLoS Negl Trop Dis":1,"STAR Protoc":2,"Cell Host Microbe":2,"Stem Cell Res Ther":2,"Clin Cancer Res":1,"Sci Rep":8,"Arthritis Rheum":1,"Biomedicines":1,"Endocrinology":1,"Exp Parasitol":1,"EMBO J":1,"Cell Mol Immunol":1,"Int J Mol Sci":1,"Nat Immunol":4,"J Exp Med":1,"Chem Biol":1,"Cell Rep":4,"Cell Microbiol":1,"Exp Ther Med":1,"Cell Death Dis":6,"J Virol":2,"J Neuroimmunol":1,"Immunology":1,"J Immunother Cancer":2,"Eur J Immunol":2,"J Comp Neurol":1,"J Hematol Oncol":1,"Mol Med":1,"Tissue Eng Part A":1,"Front Immunol":13,"J Neurotrauma":1,"Mucosal Immunol":2,"Front Pharmacol":3,"Theranostics":1,"Cells":5,"J Reprod Dev":1,"Pain Res Manag":1,"Am J Physiol Gastrointest Liver Physiol":1,"PLoS Pathog":1,"Cell Mol Gastroenterol Hepatol":4,"J Biol Chem":8,"Glia":8,"Mol Cancer":1,"Part Fibre Toxicol":1},"sortedMap":{}}]}; window.$mangular.tfRelatedProductsModuleURL = '/api/magellan/related-products-ui/widget/v2/'; THERMO_FISHER.pdp.productOrderComponent = {}; THERMO_FISHER.pdp.productOrderComponent.productDetailViewModel = {"sku":"15-0112-82","productSize":"100 µg","webId":"15-0112-82","packageDetails":[{"sku":"15-0112-81","size":"50 µg","onlinePriceApplicable":false,"entitled":true,"priced":false,"leadTimeEU":"5 business days","webId":"15-0112-81","searchStatus":true,"longTermUnavailable":false,"parentSku":false,"orderable":false,"discontinued":false,"thirdPartyProduct":false,"leadTimeCN":"1-2 weeks"},{"sku":"15-0112-82","size":"100 µg","onlinePriceApplicable":false,"entitled":true,"priced":false,"leadTimeEU":"1 business day","webId":"15-0112-82","searchStatus":true,"longTermUnavailable":false,"parentSku":true,"orderable":false,"discontinued":false,"thirdPartyProduct":false,"leadTimeCN":"1-2 weeks"},{"sku":"15-0112-83","size":"200 µg","onlinePriceApplicable":false,"entitled":true,"priced":false,"leadTimeEU":"5 business days","webId":"15-0112-83","searchStatus":true,"longTermUnavailable":false,"parentSku":false,"orderable":false,"discontinued":false,"thirdPartyProduct":false,"leadTimeCN":"1-2 weeks"}],"orderable":false,"longTermUnavailable":false,"discontinued":false}; THERMO_FISHER.pdp.productOrderComponent.productType = 'antibody'; THERMO_FISHER.pdp.productOrderComponent.productSubType = 'antibody_primary'; THERMO_FISHER.pdp.productOrderComponent.brand = 'Invitrogen'; THERMO_FISHER.pdp.productOrderComponent.userKey = "NONE"; THERMO_FISHER.pdp.productOrderComponent.productDesc = 'Description: The M1/70 monoclonal antibody reacts with mouse CD11b, the 165-170 kDa integrin alphaM. CD11b non-covalently associates with CD18 to form alphaM-beta2 integrin (Mac-1) and binds to CD54 (ICAM-1), C3bi, and fibrinogen. Mac-1 is expressed by macrophages, NK cells, granulocytes, activated lymphocytes and mouse B-1 cells in the peritoneal cavity. M1/70 is also cross-reactive to human CD11b, and can be used for the detection of this antigen on human peripheral blood monocytes, granulocytes, and a subset of NK cells. Through interactions with its ligands, CD11b participates in adhesive cell interactions.<br /><br />Applications Reported: The M1/70 antibody has been reported for use in flow cytometric analysis.<br /><br />Applications Tested: The M1/70 antibody has been tested by flow cytometric analysis of mouse splenocytes and bone marrow cells. This can be used at less than or equal to 0.125 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.<br /><br />Light sensitivity: This tandem dye is sensitive photo-induced oxidation. Please protect this vial and stained samples from light. <br /><br />Fixation: Samples can be stored in IC Fixation Buffer (<a href="https://www.thermofisher.com/order/catalog/product/00-8222-49">Product # 00-822-49</a>) (100 µL cell sample + 100 µL IC Fixation Buffer) or 1-step Fix/Lyse Solution (<a href="https://www.thermofisher.com/order/catalog/product/00-5333-54">Product # 00-5333-54</a>) for up to 3 days in the dark at 4°C with minimal impact on brightness and FRET efficiency/compensation. Some generalizations regarding fluorophore performance after fixation can be made, but clone specific performance should be determined empirically.<br /><br />Excitation: 488-561 nm; Emission: 667 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser.<br /><br />Filtration: 0.2 µm post-manufacturing filtered.'; THERMO_FISHER.pdp.productOrderComponent.imageForSchemaMarkup = 'https://www.thermofisher.com/antibody/images/650/15-0112-82_CD11b_Flow_1-20170119083539.jpg?time=20240507?time=20240507'; THERMO_FISHER.pdp.productOrderComponent.productSpecificationTableData = '[{"name":"Species Reactivity","value":"Mouse "},{"name":"Published species","value":"Fish ,Human ,Mouse "},{"name":"Host / Isotype","value":"Rat/ IgG2b, kappa"},{"name":"Recommended Isotype Control","value":"Rat IgG2b kappa Isotype Control (eB149/10H5), PE-Cyanine5, eBioscience™"},{"name":"Class","value":"Monoclonal"},{"name":"Type","value":"Antibody"},{"name":"Clone","value":"M1/70"},{"name":"Conjugate","value":"PE-Cyanine5 "},{"name":"Excitation/Emission Max","value":"568/666 nm "},{"name":"Form","value":"Liquid"},{"name":"Concentration","value":"0.2 mg/mL"},{"name":"Purification","value":"Affinity chromatography"},{"name":"Storage buffer","value":"PBS, pH 7.2"},{"name":"Contains","value":"0.09% sodium azide"},{"name":"Storage conditions","value":"4° C, store in dark, DO NOT FREEZE!"},{"name":"Shipping conditions","value":"Ambient (domestic); Wet ice (international)"},{"name":"RRID","value":"AB_468714"}]'; $m.userKey = "NONE"; angular.element(document).ready(function() { angular.bootstrap('#pdp-components', ['antibodyPdpModule']); }); THERMO_FISHER.pdp.sharedListComponent = THERMO_FISHER.pdp.sharedListComponent || {}; THERMO_FISHER.pdp.sharedListComponent.sharedList = null; </script> </div> <div class="documents"> <div class="documents-cntr" id="documents-container"> <div class="loading-wheel-lg hidden" id="documentLoadingWheel"></div> <div id="documentsUIRoot1"></div> </div>  <script defer type="text/javascript" src="/store/v2/documents/static/conditionalLoadAssets.js?version=Local&time=20240917&build-time=2024-11-22T02:34:20+0000"></script>  <script> window.THERMO_FISHER = window.THERMO_FISHER || {}; THERMO_FISHER.pdp = THERMO_FISHER.pdp || {}; THERMO_FISHER.pdp.documents = THERMO_FISHER.pdp.documents || {}; THERMO_FISHER.pdp.documents.selectedProductId = '15-0112-82'; THERMO_FISHER.pdp.documents.documentsFetched = false; THERMO_FISHER.pdp.documents.reqParam = { containerId: 'documentsUIRoot1', skus: [THERMO_FISHER.pdp.documents.selectedProductId], showCertificates: true, showSds: true, showOthers: true, expanded: 'true' }; THERMO_FISHER.pdp.documents.docSectionEle = document.getElementById("rootPdpDocLoader"); var documentLoadingWheel = document.getElementById("documentLoadingWheel"); THERMO_FISHER.pdp.documents.fetchDocuments = function() { setTimeout(function() { var docUi = document.getElementsByClassName("product-documents-ui"); if (typeof documentsConfiguration != "undefined" && typeof docUi != "undefined") { documentsConfiguration([THERMO_FISHER.pdp.documents.reqParam]); THERMO_FISHER.pdp.documents.documentsFetched = true; documentLoadingWheel.classList.add("hidden"); } else { console.log("loadDocuments: window.documentsConfiguration is UNDEFINED"); } }, 3000); }; if(THERMO_FISHER.pdp.documents.docSectionEle){ THERMO_FISHER.pdp.documents.intersectionObserver = new IntersectionObserver(function(elements) { elements.forEach(function(entry) { if(!THERMO_FISHER.pdp.documents.documentsFetched && entry.intersectionRatio >= 0.07){ documentLoadingWheel.classList.remove("hidden"); THERMO_FISHER.pdp.documents.fetchDocuments(); } }); }); THERMO_FISHER.pdp.documents.intersectionObserver.observe(THERMO_FISHER.pdp.documents.docSectionEle); } </script> </div> <div class="two-up-module-container">   <div class="two-up-row" id="bottom-cta-banner" style="display: block;"> <div class="two-up-row-divider container"> <div class="row"> <div class="span5 medium-span-5 small-span-12"> <img src="https://www.thermofisher.com/content/dam/LifeTech/global/life-sciences/Antibodies/images/guarantee.png" class="column-image" alt="guarantee_icon" loading="lazy"> <h2 class="two-up-header">Performance Guarantee</h2> <p class="two-up-paragraph">If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*</p> <a href="https://www.thermofisher.com/us/en/home/life-science/antibodies/antibody-performance-guarantee.html" class="btn two-up-btn performance-guarantee-button">Learn more</a> </div> <div class="span5 medium-span-5 small-span-12 right-content"> <img src="https://www.thermofisher.com/content/dam/LifeTech/global/life-sciences/Antibodies/images/help.png" class="column-image" alt="help_icon" loading="lazy"> <h2 class="two-up-header">We're here to help</h2> <p class="two-up-paragraph">Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.</p> <a id="tech_link" href="https://www.thermofisher.com/us/en/home/technical-resources/contact-us.15-0112-82.html?supportType=TS" class="btn two-up-btn" >Contact tech support</a> </div> </div> </div> </div> </div> </div> </div> <script> // load global functions callIfOrWhenWindowLoaded(window.THERMO_FISHER.scroll.init()); </script> <link rel="stylesheet" type="text/css" href="/order/genome-database/assets/core/dist/fonts/thermofisher.icons.css?version=Local&time=20240917&build-time=2024-11-22T02:34:20+0000"/> </div>  </div> </div> <div class="footer group"> <style> .no-logo{ min-height: 80px; } </style> <footer id="tf-global-footer" style=""> <div class="globalFooter" data-orig="tfpt-header-footer" data-app-env="prod" data-site="tf" data-hostname="www.thermofisher.com" data-x-host="www.thermofisher.com" data-env="prod" data-hash="468bd07150dbbf" data-version="4.03.29" data-analytics-section="header" data-aem-syndication-info="(sg:en-sg:anonymous:https-tf)" data-aem-syndication-timestamp="globalHeader: Wed, 27 Nov 2024 23:24:21 GMT" data-optional-selectors="inlineCss,globalRoute">           <script type="text/javascript"> window.performance && window.performance.mark && window.performance.mark("globalFooter:renderBegin"); </script>  <style data-inline-file-name='footer.min.css' data-inline-site='tf'>/* Hash: 468bd07150dbbf Source: /tf/css/dist/footer.min.css */ @charset "UTF-8";@font-face{font-family:HelveticaNeue;src:url(/designsystem-cdn/fonts/HelveticaNeueLTW01-35Thin.eot?#iefix);src:url(/designsystem-cdn/fonts/HelveticaNeueLTW01-35Thin.eot?#iefix) format("eot"),url(/designsystem-cdn/fonts/HelveticaNeueLTW01-35Thin.woff2) format("woff2");font-weight:lighter;font-style:normal;font-display:swap}@font-face{font-family:HelveticaNeue;src:url(/designsystem-cdn/fonts/HelveticaNeueLTW01-35Thin.eot?#iefix);src:url(/designsystem-cdn/fonts/HelveticaNeueLTW01-35Thin.eot?#iefix) format("eot"),url(/designsystem-cdn/fonts/HelveticaNeueLTW01-35Thin.woff2) format("woff2");font-weight:100;font-style:normal;font-display:swap}@font-face{font-family:HelveticaNeue;src:url(/designsystem-cdn/fonts/HelveticaNeueLTW01-45Light.eot?#iefix);src:url(/designsystem-cdn/fonts/HelveticaNeueLTW01-45Light.eot?#iefix) format("eot"),url(/designsystem-cdn/fonts/HelveticaNeueLTW01-45Light.woff2) format("woff2");font-weight:200;font-style:normal;font-display:swap}@font-face{font-family:HelveticaNeue;src:url(/designsystem-cdn/fonts/HelveticaNeueLTW01-45Light.eot?#iefix);src:url(/designsystem-cdn/fonts/HelveticaNeueLTW01-45Light.eot?#iefix) format("eot"),url(/designsystem-cdn/fonts/HelveticaNeueLTW01-45Light.woff2) format("woff2");font-weight:300;font-style:normal;font-display:swap}@font-face{font-family:HelveticaNeue;src:url(/designsystem-cdn/fonts/HelveticaNeueLTW01-55Roman.eot?#iefix);src:url(/designsystem-cdn/fonts/HelveticaNeueLTW01-55Roman.eot?#iefix) format("eot"),url(/designsystem-cdn/fonts/HelveticaNeueLTW01-55Roman.woff2) format("woff2");font-style:normal;font-display:swap}@font-face{font-family:HelveticaNeue;src:url(/designsystem-cdn/fonts/HelveticaNeueLTW01-55Roman.eot?#iefix);src:url(/designsystem-cdn/fonts/HelveticaNeueLTW01-55Roman.eot?#iefix) format("eot"),url(/designsystem-cdn/fonts/HelveticaNeueLTW01-55Roman.woff2) format("woff2");font-weight:400;font-style:normal;font-display:swap}@font-face{font-family:HelveticaNeue;src:url(/designsystem-cdn/fonts/HelveticaNeueLTW01-56Italic.eot?#iefix);src:url(/designsystem-cdn/fonts/HelveticaNeueLTW01-56Italic.eot?#iefix) format("eot"),url(/designsystem-cdn/fonts/HelveticaNeueLTW01-56Italic.woff2) format("woff2");font-weight:400;font-style:italic;font-display:swap}@font-face{font-family:HelveticaNeue;src:url(/designsystem-cdn/fonts/HelveticaNeueLTW01-65Medium.eot?#iefix);src:url(/designsystem-cdn/fonts/HelveticaNeueLTW01-65Medium.eot?#iefix) format("eot"),url(/designsystem-cdn/fonts/HelveticaNeueLTW01-65Medium.woff2) format("woff2");font-weight:500;font-style:normal;font-display:swap}@font-face{font-family:HelveticaNeue;src:url(/designsystem-cdn/fonts/HelveticaNeueLTW01-65Medium.eot?#iefix);src:url(/designsystem-cdn/fonts/HelveticaNeueLTW01-65Medium.eot?#iefix) format("eot"),url(/designsystem-cdn/fonts/HelveticaNeueLTW01-65Medium.woff2) format("woff2");font-weight:600;font-style:normal;font-display:swap}@font-face{font-family:HelveticaNeue;src:url(/designsystem-cdn/fonts/HelveticaNeueLTW01-75Bold.eot?#iefix);src:url(/designsystem-cdn/fonts/HelveticaNeueLTW01-75Bold.eot?#iefix) format("eot"),url(/designsystem-cdn/fonts/HelveticaNeueLTW01-75Bold.woff2) format("woff2");font-weight:700;font-style:normal;font-display:swap}@font-face{font-family:HelveticaNeue;src:url(/designsystem-cdn/fonts/HelveticaNeueLTW01-75Bold.eot?#iefix);src:url(/designsystem-cdn/fonts/HelveticaNeueLTW01-75Bold.eot?#iefix) format("eot"),url(/designsystem-cdn/fonts/HelveticaNeueLTW01-75Bold.woff2) format("woff2");font-weight:800;font-style:normal;font-display:swap}@font-face{font-family:HelveticaNeue;src:url(/designsystem-cdn/fonts/HelveticaNeueLTW01-75Bold.eot?#iefix);src:url(/designsystem-cdn/fonts/HelveticaNeueLTW01-75Bold.eot?#iefix) format("eot"),url(/designsystem-cdn/fonts/HelveticaNeueLTW01-75Bold.woff2) format("woff2");font-weight:900;font-style:normal;font-display:swap}@font-face{font-family:HelveticaNeue;src:url(/designsystem-cdn/fonts/HelveticaNeueLTW01-75Bold.eot?#iefix);src:url(/designsystem-cdn/fonts/HelveticaNeueLTW01-75Bold.eot?#iefix) format("eot"),url(/designsystem-cdn/fonts/HelveticaNeueLTW01-75Bold.woff2) format("woff2");font-weight:700;font-style:normal;font-display:swap}footer,header{font-family:HelveticaNeue,sans-serif;-ms-text-size-adjust:100%;-webkit-text-size-adjust:100%;max-width:100%;scroll-behavior:smooth;color:#1b1b1d;margin:0}footer *,header *{-webkit-box-sizing:border-box;-moz-box-sizing:border-box;box-sizing:border-box}footer :after,footer :before,header :after,header :before{-webkit-box-sizing:border-box;-moz-box-sizing:border-box;box-sizing:border-box}footer :focus-visible,header :focus-visible{outline:2px solid #802eff}footer input:focus-visible,header input:focus-visible{outline:0}footer .bold-label,header .bold-label{font-weight:700}footer .h1,footer .h2,footer .h3,footer .h4,footer .h5,footer .h6,footer body,footer h1,footer h2,footer h3,footer h4,footer h5,footer h6,header .h1,header .h2,header .h3,header .h4,header .h5,header .h6,header body,header h1,header h2,header h3,header h4,header h5,header h6{color:#222}footer .text-light,footer .text-light .display-1,footer .text-light .display-2,footer .text-light .display-3,footer .text-light .display-4,footer .text-light .h1,footer .text-light .h2,footer .text-light .h3,footer .text-light .h4,footer .text-light .h5,footer .text-light .h6,footer .text-light body,footer .text-light h1,footer .text-light h2,footer .text-light h3,footer .text-light h4,footer .text-light h5,footer .text-light h6,header .text-light,header .text-light .display-1,header .text-light .display-2,header .text-light .display-3,header .text-light .display-4,header .text-light .h1,header .text-light .h2,header .text-light .h3,header .text-light .h4,header .text-light .h5,header .text-light .h6,header .text-light body,header .text-light h1,header .text-light h2,header .text-light h3,header .text-light h4,header .text-light h5,header .text-light h6{color:#fff}footer body,header body{margin:0;font-size:16px;line-height:26px}footer p,header p{margin-top:0;margin-bottom:0;font-size:16px;line-height:26px}footer .p-grey,header .p-grey{color:#54545c}footer .text-center,header .text-center{text-align:center}footer .alt,header .alt{font-size:16px;line-height:26px}footer .text-size-14,header .text-size-14{font-size:14px;line-height:22px}footer a,header a{text-decoration:none;color:#1b1b1d}footer a:hover,header a:hover{text-decoration:none;color:#1b1b1d}footer a:visited,header a:visited{text-decoration:none;color:#1b1b1d}footer .disabled,header .disabled{color:#a2a2a2}footer .label-medium,header .label-medium{color:#222;font-size:16px;line-height:26px;font-weight:400}footer .label-bold,header .label-bold{color:#222;font-size:16px;line-height:26px;font-weight:bolder}footer .hint,header .hint{font-size:14px;line-height:30.727268px}footer .blockquote,header .blockquote{color:#222;font-size:20.571424px;line-height:33.090902px;margin-bottom:0}footer .alt-color,header .alt-color{color:#54545c}footer .success,header .success{color:#3bad2f}footer .warning,header .warning{color:#ed7700}footer .error,header .error{color:#e71316}footer .thin,header .thin{font-weight:lighter}footer .light,header .light{font-weight:300}footer .italic,header .italic{font-style:italic}footer .medium,header .medium{font-weight:700}footer .bold,header .bold{font-weight:bolder}footer .h1,footer .h2,footer .h3,footer .h5,footer h1,footer h2,footer h3,footer h5,header .h1,header .h2,header .h3,header .h5,header h1,header h2,header h3,header h5{font-weight:400;margin:0;padding-bottom:10px}footer .h4,footer h4,header .h4,header h4{font-weight:600;margin:0;padding-bottom:10px}footer .h6,footer h6,header .h6,header h6{font-weight:400;margin:0;padding-bottom:10px}footer .display-1,footer .display-2,footer .display-3,footer .display-4,header .display-1,header .display-2,header .display-3,header .display-4{font-family:HelveticaNeueLight,Helvetica,Roboto,"Segoe UI",Arial,sans-serif;font-weight:lighter}footer .h1,footer h1,header .h1,header h1{font-size:32px;line-height:40px}footer .h2,footer h2,header .h2,header h2{font-size:26px;line-height:33px}footer .h3,footer h3,header .h3,header h3{font-size:22px;line-height:28px}footer .h4,footer h4,header .h4,header h4{font-size:20px;line-height:25px}footer .h5,footer h5,header .h5,header h5{font-size:18px;line-height:23px}footer .h6,footer h6,header .h6,header h6{font-size:16px;line-height:20px}footer .display-1,header .display-1{font-size:40px;line-height:50px}footer .display-2,header .display-2{font-size:32px;line-height:40px}footer .display-3,header .display-3{font-size:24px;line-height:30px}footer .display-4,header .display-4{font-weight:300;font-size:30px;line-height:38px}@media (max-width:768px){footer .h1,footer h1,header .h1,header h1{font-size:26px;line-height:33px}footer .h2,footer h2,header .h2,header h2{font-size:21px;line-height:26px}footer .h3,footer h3,header .h3,header h3{font-size:18px;line-height:23px}footer .h4,footer h4,header .h4,header h4{font-size:16px;line-height:20px}footer .h5,footer h5,header .h5,header h5{font-size:16px;line-height:20px}footer .h6,footer h6,header .h6,header h6{font-size:16px;line-height:20px}footer .display-1,header .display-1{font-size:40px;line-height:50px}footer .display-2,header .display-2{font-size:32px;line-height:40px}footer .display-3,header .display-3{font-size:24px;line-height:30px}footer .display-4,header .display-4{font-weight:300;font-size:30px;line-height:38px}}footer .font-size-14,header .font-size-14{font-size:14px}footer .font-size-16,header .font-size-16{font-size:16px}footer .font-size-18,header .font-size-18{font-size:18px}footer .font-size-20,header .font-size-20{font-size:20px}footer .font-size-22,header .font-size-22{font-size:22px}footer .font-size-24,header .font-size-24{font-size:24px}footer .font-size-26,header .font-size-26{font-size:26px}footer fieldset,header fieldset{display:block;margin-inline-start:0;margin-inline-end:0;padding-block-start:0;padding-inline-start:0;padding-inline-end:0;padding-block-end:0;border-width:0;border-style:none}@media print{footer .cmp-p-pageheadinghero,header .cmp-p-pageheadinghero{display:none}footer .cmp-p-manualnav,header .cmp-p-manualnav{display:none}footer .header-cmp,header .header-cmp{display:none}footer .cmp-p-anchorlist,header .cmp-p-anchorlist{display:none}footer .cmp-p-ctaitem,header .cmp-p-ctaitem{display:none}footer .footer,header .footer{display:none}footer .cmp-p-testimonial,header .cmp-p-testimonial{display:none}footer td,footer th,header td,header th{padding-top:4px;padding-bottom:4px;height:30px}}.m-l1{margin:16px}.m-l2{margin:24px}.m-l3{margin:32px}.m-l4{margin:48px}.m-l5{margin:64px}.m-l0{margin:0!important}.mx-l1{margin:0 16px}.mx-l2{margin:0 24px}.mx-l3{margin:0 32px}.mx-l4{margin:0 48px}.mx-l5{margin:0 64px}.mx-l1{margin:16px 0}.mx-l2{margin:24px 0}.mx-l3{margin:32px 0}.mx-l4{margin:48px 0}.mx-l5{margin:64px 0}.mt-l1{margin-top:16px}.mt-l2{margin-top:24px}.mt-l3{margin-top:32px}.mt-l4{margin-top:48px}.mt-l5{margin-top:64px}.mb-l1{margin-bottom:16px}.mb-l2{margin-bottom:24px}.mb-l3{margin-bottom:32px}.mb-l4{margin-bottom:48px}.mb-l5{margin-bottom:64px}.ml-l1{margin-left:16px}.ml-l2{margin-left:24px}.ml-l3{margin-left:32px}.ml-l4{margin-left:48px}.ml-l5{margin-left:64px}.mr-l1{margin-right:16px}.mr-l2{margin-right:24px}.mr-l3{margin-right:32px}.mr-l4{margin-right:48px}.mr-l5{margin-right:64px}.p-l1{padding:16px}.p-l2{padding:24px}.p-l3{padding:32px}.p-l4{padding:48px}.p-l5{padding:64px}.p-l0{padding:0!important}.px-l1{padding:0 16px}.px-l2{padding:0 24px}.px-l3{padding:0 32px}.px-l4{padding:0 48px}.px-l5{padding:0 64px}.px-l1{padding:16px 0}.px-l2{padding:24px 0}.px-l3{padding:32px 0}.px-l4{padding:48px 0}.px-l5{padding:64px 0}.pt-l1{padding-top:16px}.pt-l2{padding-top:24px}.pt-l3{padding-top:32px}.pt-l4{padding-top:48px}.pt-l5{padding-top:64px}.pb-l1{padding-bottom:16px}.pb-l2{padding-bottom:24px}.pb-l3{padding-bottom:32px}.pb-l4{padding-bottom:48px}.pb-l5{padding-bottom:64px}.pl-l1{padding-left:16px}.pl-l2{padding-left:24px}.pl-l3{padding-left:32px}.pl-l4{padding-left:48px}.pl-l5{padding-left:64px}.pr-l1{padding-right:16px}.pr-l2{padding-right:24px}.pr-l3{padding-right:32px}.pr-l4{padding-right:48px}.pr-l5{padding-right:64px}.mt-s0{margin-top:0}.mt-s1{margin-top:2px}.mt-s2{margin-top:4px}.mt-s3{margin-top:8px}.mt-s4{margin-top:12px}.mt-s5{margin-top:16px}.mt-s6{margin-top:24px}.mt-s7{margin-top:32px}.mt-s8{margin-top:40px}.mt-s9{margin-top:48px}.mb-s0{margin-bottom:0}.mb-s1{margin-bottom:2px}.mb-s2{margin-bottom:4px}.mb-s3{margin-bottom:8px}.mb-s4{margin-bottom:12px}.mb-s5{margin-bottom:16px}.mb-s6{margin-bottom:24px}.mb-s7{margin-bottom:32px}.mb-s8{margin-bottom:40px}.mb-s9{margin-bottom:48px}.ml-s0{margin-left:0}.ml-s1{margin-left:2px}.ml-s2{margin-left:4px}.ml-s3{margin-left:8px}.ml-s4{margin-left:12px}.ml-s5{margin-left:16px}.ml-s6{margin-left:24px}.ml-s7{margin-left:32px}.ml-s8{margin-left:40px}.ml-s9{margin-left:48px}.mr-s0{margin-right:0}.mr-s1{margin-right:2px}.mr-s2{margin-right:4px}.mr-s3{margin-right:8px}.mr-s4{margin-right:12px}.mr-s5{margin-right:16px}.mr-s6{margin-right:24px}.mr-s7{margin-right:32px}.mr-s8{margin-right:40px}.mr-s9{margin-right:48px}.pt-s0{padding-top:0}.pt-s1{padding-top:2px}.pt-s2{padding-top:4px}.pt-s3{padding-top:8px}.pt-s4{padding-top:12px}.pt-s5{padding-top:16px}.pt-s6{padding-top:24px}.pt-s7{padding-top:32px}.pt-s8{padding-top:40px}.pt-s9{padding-top:48px}.pb-s0{padding-bottom:0}.pb-s1{padding-bottom:2px}.pb-s2{padding-bottom:4px}.pb-s3{padding-bottom:8px}.pb-s4{padding-bottom:12px}.pb-s5{padding-bottom:16px}.pb-s6{padding-bottom:24px}.pb-s7{padding-bottom:32px}.pb-s8{padding-bottom:40px}.pb-s9{padding-bottom:48px}.pl-s0{padding-left:0}.pl-s1{padding-left:2px}.pl-s2{padding-left:4px}.pl-s3{padding-left:8px}.pl-s4{padding-left:12px}.pl-s5{padding-left:16px}.pl-s6{padding-left:24px}.pl-s7{padding-left:32px}.pl-s8{padding-left:40px}.pl-s9{padding-left:48px}.pr-s0{padding-right:0}.pr-s1{padding-right:2px}.pr-s2{padding-right:4px}.pr-s3{padding-right:8px}.pr-s4{padding-right:12px}.pr-s5{padding-right:16px}.pr-s6{padding-right:24px}.pr-s7{padding-right:32px}.pr-s8{padding-right:40px}.pr-s9{padding-right:48px}footer{padding-top:40px;background-color:#fff}footer .footer .footer-menu{width:100%;background-color:#f7f7f7;padding:0}footer .footer .footer-menu-container{max-width:1440px;margin:auto;padding:0;font-size:14px;display:flex;justify-content:space-between;flex-direction:column}footer .footer .footer-menu-col{padding-bottom:8px}footer .footer .footer-menu-col ul{list-style-type:none;margin-left:0;padding-inline-start:0;max-height:0;transition:height .3s ease-in;overflow:hidden;margin-bottom:-12px}footer .footer .footer-menu-col ul li{font-weight:400;line-height:24px}footer .footer .footer-menu-col ul li .external-link-icon{height:16px;width:16px;margin-left:10px;margin-bottom:-2px;display:inline-block;background-image:url("data:image/svg+xml,%3Csvg xmlns='http://www.w3.org/2000/svg' viewBox='0 0 16 16'%3E%3Cpath class='external-link-icon' d='M15 1V8.24H13V4.4l-6 6L5.56 9l6-6H7.75V1ZM11.28 13.09H2.89V4.7H5.61V2.8H1V15H13.17v-4.7H11.28Z'/%3E%3C/svg%3E")}footer .footer .footer-menu-col.open .footer-menu-label .icon .plus-icon-svg{display:none}footer .footer .footer-menu-col.open .footer-menu-label .icon .minus-icon-svg{display:inline-block}footer .footer .footer-menu-col.open ul{max-height:500px;transition:height .3s ease-out;margin:0 16px 16px}footer .footer .footer-menu-label{font-weight:700;line-height:22px;padding:16px;border-top:1px solid #e5e5e5}footer .footer .footer-menu-label .icon{float:right;margin-right:16px;width:24px;display:inline-block;pointer-events:none}footer .footer .footer-menu-label .icon .minus-icon-svg{display:none}footer .footer .footer-menu-label a,footer .footer .footer-menu-label a:visited{color:#222}footer .footer .footer-legal{width:100%}footer .footer .footer-legal-container{max-width:1440px;margin:auto;padding:0 16px;display:flex;justify-content:space-between;flex-direction:column;font-size:14px}footer .footer .footer-legal-container-select{display:inline-block;text-align:left;justify-content:flex-start;align-items:center;font-weight:500;font-size:14px;line-height:22px;width:100%;margin-bottom:16px}footer .footer .footer-legal-container-select .ml-l1{margin-left:0;margin-right:0}footer .footer .footer-legal-container-select select{margin-bottom:0;background-color:transparent}footer .footer .footer-legal-container-select label{display:block;padding-bottom:6px;padding-right:12px}footer .footer .footer-legal-container-select .cmp-ctaitem{margin-top:0}footer .footer .footer-legal-container-select .cmp-ctaitem button{display:inline-block;text-align:center;margin:0;border-radius:3px;font-weight:700;font-size:14px;padding:0 24px 0 24px;box-sizing:border-box;line-height:32px;text-decoration:none;cursor:pointer;transition:background 250ms ease-in-out,transform 150ms ease;-webkit-appearance:none;-moz-appearance:none;width:auto;color:#555759;background-color:#fff;border:solid 1px #dcdcdc}footer .footer .footer-legal-container-select .cmp-ctaitem__anchor{margin-left:16px}footer .footer .footer-legal-container-select .cmp-p-dropdown{display:inherit;float:left;margin-right:16px}footer .footer .footer-legal-container-select .cmp-p-dropdown .cmp-dropdown{position:relative}footer .footer .footer-legal-container-select .cmp-p-dropdown .cmp-dropdown__toggle{border:1px solid #ccc;border-left:4px solid #0079d8;min-width:220px;text-align:left;font-weight:700;line-height:30px;height:34px}footer .footer .footer-legal-container-select .cmp-p-dropdown .cmp-dropdown__toggleicon{height:0;width:0;margin:12px;border-left:4px solid transparent;border-right:4px solid transparent;border-top:6px solid #222}footer .footer .footer-legal-container-select .cmp-p-dropdown .cmp-dropdown__toggleicon:after{display:none}footer .footer .footer-legal-container-select .cmp-p-dropdown .cmp-dropdown select{appearance:none}footer .footer .footer-legal-container-select .cmp-p-dropdown .cmp-dropdown::after{content:"‣";position:absolute;top:6px;right:12px;font-size:34px;transform:rotate(90deg);z-index:-1}footer .footer .footer-legal-container #form-select-language{margin-top:0}footer .footer .footer-legal-container .cn-footer{color:#54545c;font-size:12px;margin-bottom:120px}footer .footer .footer-legal-link{font-size:12px;font-weight:400;line-height:15px}footer .footer .footer-legal-link ul{list-style-type:none;margin-left:0;padding-inline-start:0;margin-bottom:0}footer .footer .footer-legal-link ul li{padding-bottom:12px}footer .footer .footer-legal-link ul li a{margin-bottom:12px}footer .footer .footer-legal .all-rights{display:block;color:#54545c;margin-bottom:12px;max-width:600px}footer .footer .footer-legal-logo{width:99px;margin-top:24px}footer .footer .footer-legal .privacy-policy-bold{font-weight:700}footer .footer .footer-legal-country{display:flex;margin-bottom:0;justify-content:flex-start}footer .footer .footer-legal-country .country-flag{height:16px;width:16px;display:inline-block;margin-right:16px}footer .footer a,footer .footer a:link,footer .footer a:visited{color:#54545c}@media (min-width:576px){footer .footer .footer-legal-container-select .cmp-p-dropdown{margin-bottom:0}footer .footer .footer-legal-link{font-size:14px;font-weight:400;line-height:22px}footer .footer .footer-legal-link ul li{padding-bottom:0;display:inline-block;padding-right:16px;padding-left:16px;border-right:1px solid #dcdcdc}footer .footer .footer-legal-link ul li:first-child{padding-left:0}footer .footer .footer-legal-link ul li:last-child{border-right:none}footer .footer .footer-legal-list .privacy-policy-bold{font-weight:700}}@media (min-width:768px){footer .footer .footer-legal-link{font-size:11px;line-height:13px;display:flex;align-items:center}footer .footer .footer-legal-logo{width:120px;margin:16px 0}footer .footer .footer-legal-logo .tf-logo-cls-1{fill:#e71316}footer .footer .footer-legal-logo .tf-logo-cls-2{fill:#fff}footer .footer .footer-legal-list{width:100%;margin-left:24px}footer .footer .footer-legal-list ul{margin-top:0;margin-bottom:0}footer .footer .footer-legal-list li{margin-bottom:10px}footer .footer .footer-legal-list .privacy-policy-bold{font-weight:700}footer .footer .footer-legal .all-rights{display:block;color:#54545c;margin-bottom:12px;max-width:600px}footer .footer .footer-legal-country{margin-bottom:14px;min-width:140px}footer .footer .footer-legal .footer-legal-country{display:flex;margin-top:16px;justify-content:flex-end}footer .footer .footer-legal .footer-legal-country .country-flag{height:24px;margin-right:5px}}@media (min-width:992px){footer .footer .footer-menu{padding:0 24px}footer .footer .footer-menu-container{flex-direction:row;padding:0 16px}footer .footer .footer-menu-col{margin-top:0;margin-block-start:14px}footer .footer .footer-menu-col.open ul{margin:0}footer .footer .footer-menu-col ul{display:block;max-height:500px;padding-bottom:42px;margin-block-start:9px}footer .footer .footer-menu-col ul li{min-height:30px}footer .footer .footer-menu-label{border-top:none;padding:16px 0 0}footer .footer .footer-menu-label .icon{display:none}footer .footer .footer-legal-container{padding-bottom:42px;margin-top:24px}footer .footer .footer-legal-container .cn-footer{margin-bottom:0}footer .footer .footer-legal .privacy-policy-bold{font-weight:700}}@media (min-width:1200px){footer .footer .footer-legal-container-select{display:flex;text-align:left;align-self:flex-end;justify-content:flex-end;align-items:center;font-weight:500;font-size:14px;line-height:22px;width:100%;margin-bottom:16px}footer .footer .footer-legal-container #form-select-language{margin-top:-32px}footer .footer .footer-legal .privacy-policy-bold{font-weight:700}}.cmp-dropdown{position:relative}.cmp-dropdown *{box-sizing:border-box}.cmp-dropdown .cmp-dropdown__toggle{position:relative;display:inline-block;padding:0 30px 0 10px;line-height:40px;border:1px solid #222;text-decoration:none;color:#222}.cmp-dropdown .cmp-dropdown__toggleicon{position:absolute;height:40px;width:20px;transform:translate(0,0);top:0;right:0}.cmp-dropdown .cmp-dropdown__toggleicon:after{font-family:icomoon;font-size:8px;content:"\ee2c";display:inline-block}.cmp-dropdown .cmp-dropdown__menu{display:none;position:absolute;z-index:1;transform:translate(0,0);will-change:transform;padding:5px;background-color:#eee;border:1px solid #222}.cmp-dropdown.open .cmp-dropdown__toggleicon:after{transform:rotate(180deg)}.cmp-dropdown.open .cmp-dropdown__menu{display:block}.footer-menu-container ul li a img{width:14px;height:14px;top:2px;position:relative} /*# sourceMappingURL=footer.min.css.map */ </style> <script type="text/javascript" src="/store/global-header-footer-static/tf/js/utilities.min.468bd07150dbbf.js" async></script>  <div class="footer "> <div class="footer-menu"> <div class="footer-menu-container"> <div id="footer-menu-category-1" class="footer-menu-col pragma-toggle-component"> <div class="footer-menu-label pragma-toggle" data-analytics-section="footer" data-analytics-container="Ordering" data-toggle="#footer-menu-category-1" data-toggle-classes="open"> Ordering <span class="icon"> <svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 24 24" class="plus-icon-svg" data-toggle="#footer-menu-category-1" data-toggle-classes="open"> <title>Plus Icon</title> <g> <path d="M22,13H13v9H11V13H2V11h9V2h2v9h9Z" /> </g> </svg> <svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 24 24" class="minus-icon-svg" data-toggle="#footer-menu-category-1" data-toggle-classes="open"> <title>Minus Icon</title> <g> <path d="M22,11v2H2V11Z" /> </g> </svg> </span> </div> <ul> <li> <a href="/store/orders/solu" onclick="" id="footer-link-1-1" data-analytics-section="footer" data-analytics-container="Ordering" data-analytics-text="Order Status">Order Status <span></span> </a> </li> <li> <a href="/sg/en/home/support/how-to-place-orders.html" onclick="" id="footer-link-1-4" data-analytics-section="footer" data-analytics-container="Ordering" data-analytics-text="Order Help">Order Help <span></span> </a> </li> <li> <a href="/store/v2/quick-order" onclick="" id="footer-link-1-5" data-analytics-section="footer" data-analytics-container="Ordering" data-analytics-text="Quick Order">Quick Order <span></span> </a> </li> <li> <a href="/sg/en/home/products-and-services/supply-center.html" onclick="" id="footer-link-1-6" data-analytics-section="footer" data-analytics-container="Ordering" data-analytics-text="Supply Center">Supply Center <span></span> </a> </li> <li> <a href="/sg/en/home/digital-solutions/ecommerce/b2b.html" onclick="" id="footer-link-1-7" data-analytics-section="footer" data-analytics-container="Ordering" data-analytics-text="eProcurement">eProcurement <span></span> </a> </li> </ul> </div> <div id="footer-menu-category-2" class="footer-menu-col pragma-toggle-component"> <div class="footer-menu-label pragma-toggle" data-analytics-section="footer" data-analytics-container="Support" data-toggle="#footer-menu-category-2" data-toggle-classes="open"> Support <span class="icon"> <svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 24 24" class="plus-icon-svg" data-toggle="#footer-menu-category-2" data-toggle-classes="open"> <title>Plus Icon</title> <g> <path d="M22,13H13v9H11V13H2V11h9V2h2v9h9Z" /> </g> </svg> <svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 24 24" class="minus-icon-svg" data-toggle="#footer-menu-category-2" data-toggle-classes="open"> <title>Minus Icon</title> <g> <path d="M22,11v2H2V11Z" /> </g> </svg> </span> </div> <ul> <li> <a href="/sg/en/home/support.html" onclick="" id="footer-link-2-1" data-analytics-section="footer" data-analytics-container="Support" data-analytics-text="Help and Support">Help and Support <span></span> </a> </li> <li> <a href="/sg/en/home/technical-resources/contact-us.html" onclick="" id="footer-link-2-2" data-analytics-section="footer" data-analytics-container="Support" data-analytics-text="Contact Us">Contact Us <span></span> </a> </li> <li> <a href="/sg/en/home/technical-resources/technical-reference-library.html" onclick="" id="footer-link-2-3" data-analytics-section="footer" data-analytics-container="Support" data-analytics-text="Technical Support Centers">Technical Support Centers <span></span> </a> </li> <li> <a href="/sg/en/home/support/documents-certificates.html" onclick="" id="footer-link-2-4" data-analytics-section="footer" data-analytics-container="Support" data-analytics-text="Documents and Certificates">Documents and Certificates <span></span> </a> </li> <li> <a href="javascript:KAMPYLE_ONSITE_SDK.showForm(29308);void(0);" onclick="" id="footer-link-2-5" data-analytics-section="footer" data-analytics-container="Support" data-analytics-text="Report a Site Issue">Report a Site Issue <span></span> </a> </li> </ul> </div> <div id="footer-menu-category-3" class="footer-menu-col pragma-toggle-component"> <div class="footer-menu-label pragma-toggle" data-analytics-section="footer" data-analytics-container="Resources" data-toggle="#footer-menu-category-3" data-toggle-classes="open"> Resources <span class="icon"> <svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 24 24" class="plus-icon-svg" data-toggle="#footer-menu-category-3" data-toggle-classes="open"> <title>Plus Icon</title> <g> <path d="M22,13H13v9H11V13H2V11h9V2h2v9h9Z" /> </g> </svg> <svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 24 24" class="minus-icon-svg" data-toggle="#footer-menu-category-3" data-toggle-classes="open"> <title>Minus Icon</title> <g> <path d="M22,11v2H2V11Z" /> </g> </svg> </span> </div> <ul> <li> <a href="/sg/en/home/technical-resources/learning-centers.html" onclick="" id="footer-link-3-1" data-analytics-section="footer" data-analytics-container="Resources" data-analytics-text="Learning Centers">Learning Centers <span></span> </a> </li> <li> <a href="/sg/en/home/products-and-services/promotions.html" onclick="" id="footer-link-3-2" data-analytics-section="footer" data-analytics-container="Resources" data-analytics-text="Promotions">Promotions <span></span> </a> </li> <li> <a href="/sg/en/home/about-us/events.html" onclick="" id="footer-link-3-3" data-analytics-section="footer" data-analytics-container="Resources" data-analytics-text="Events and Webinars">Events and Webinars <span></span> </a> </li> <li> <a href="/sg/en/home/communities-social/socialhub.html" onclick="" id="footer-link-3-4" data-analytics-section="footer" data-analytics-container="Resources" data-analytics-text="Social Media">Social Media <span></span> </a> </li> </ul> </div> <div id="footer-menu-category-4" class="footer-menu-col pragma-toggle-component"> <div class="footer-menu-label pragma-toggle" data-analytics-section="footer" data-analytics-container="About Thermo Fisher" data-toggle="#footer-menu-category-4" data-toggle-classes="open"> About Thermo Fisher <span class="icon"> <svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 24 24" class="plus-icon-svg" data-toggle="#footer-menu-category-4" data-toggle-classes="open"> <title>Plus Icon</title> <g> <path d="M22,13H13v9H11V13H2V11h9V2h2v9h9Z" /> </g> </svg> <svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 24 24" class="minus-icon-svg" data-toggle="#footer-menu-category-4" data-toggle-classes="open"> <title>Minus Icon</title> <g> <path d="M22,11v2H2V11Z" /> </g> </svg> </span> </div> <ul> <li> <a href="https://corporate.thermofisher.com/en/home.html" onclick="" id="footer-link-4-1" data-analytics-section="footer" data-analytics-container="About Thermo Fisher" data-analytics-text="About Us">About Us <img src="/store/global-header-footer-static/global/svg/external-link-bold.svg" alt="About Us"> <span></span> </a> </li> <li> <a href="https://jobs.thermofisher.com/global/en" onclick="" id="footer-link-4-2" data-analytics-section="footer" data-analytics-container="About Thermo Fisher" data-analytics-text="Careers">Careers <img src="/store/global-header-footer-static/global/svg/external-link-bold.svg" alt="Careers"> <span></span> </a> </li> <li> <a href="http://ir.thermofisher.com/investors/Investor-Overview/default.aspx" onclick="" id="footer-link-4-3" data-analytics-section="footer" data-analytics-container="About Thermo Fisher" data-analytics-text="Investors">Investors <img src="/store/global-header-footer-static/global/svg/external-link-bold.svg" alt="Investors"> <span></span> </a> </li> <li> <a href="https://thermofisher.mediaroom.com" onclick="" id="footer-link-4-4" data-analytics-section="footer" data-analytics-container="About Thermo Fisher" data-analytics-text="News">News <img src="/store/global-header-footer-static/global/svg/external-link-bold.svg" alt="News"> <span></span> </a> </li> <li> <a href="http://corporate.thermofisher.com/en/responsibility.html" onclick="" id="footer-link-4-5" data-analytics-section="footer" data-analytics-container="About Thermo Fisher" data-analytics-text="Social Responsibility">Social Responsibility <img src="/store/global-header-footer-static/global/svg/external-link-bold.svg" alt="Social Responsibility"> <span></span> </a> </li> <li> <a href="/sg/en/home/global/trademark-information.html" onclick="" id="footer-link-4-6" data-analytics-section="footer" data-analytics-container="About Thermo Fisher" data-analytics-text="Trademarks">Trademarks <span></span> </a> </li> </ul> </div> <div id="footer-menu-category-5" class="footer-menu-col pragma-toggle-component"> <div class="footer-menu-label pragma-toggle" data-analytics-section="footer" data-analytics-container="Our Portfolio" data-toggle="#footer-menu-category-5" data-toggle-classes="open"> Our Portfolio <span class="icon"> <svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 24 24" class="plus-icon-svg" data-toggle="#footer-menu-category-5" data-toggle-classes="open"> <title>Plus Icon</title> <g> <path d="M22,13H13v9H11V13H2V11h9V2h2v9h9Z" /> </g> </svg> <svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 24 24" class="minus-icon-svg" data-toggle="#footer-menu-category-5" data-toggle-classes="open"> <title>Minus Icon</title> <g> <path d="M22,11v2H2V11Z" /> </g> </svg> </span> </div> <ul> <li> <a href="/sg/en/home/brands/thermo-scientific.html" onclick="" id="footer-link-5-1" data-analytics-section="footer" data-analytics-container="Our Portfolio" data-analytics-text="Thermo Scientific">Thermo Scientific <span></span> </a> </li> <li> <a href="/sg/en/home/brands/applied-biosystems.html" onclick="" id="footer-link-5-2" data-analytics-section="footer" data-analytics-container="Our Portfolio" data-analytics-text="Applied Biosystems">Applied Biosystems <span></span> </a> </li> <li> <a href="/sg/en/home/brands/invitrogen.html" onclick="" id="footer-link-5-3" data-analytics-section="footer" data-analytics-container="Our Portfolio" data-analytics-text="Invitrogen">Invitrogen <span></span> </a> </li> <li> <a href="/sg/en/home/brands/gibco.html" onclick="" id="footer-link-5-4" data-analytics-section="footer" data-analytics-container="Our Portfolio" data-analytics-text="Gibco">Gibco <span></span> </a> </li> <li> <a href="/sg/en/home/brands/ion-torrent.html" onclick="" id="footer-link-5-5" data-analytics-section="footer" data-analytics-container="Our Portfolio" data-analytics-text="Ion Torrent">Ion Torrent <span></span> </a> </li> <li> <a href="/sg/en/home/brands/fisher-scientific.html" onclick="" id="footer-link-5-6" data-analytics-section="footer" data-analytics-container="Our Portfolio" data-analytics-text="Fisher Scientific">Fisher Scientific <span></span> </a> </li> <li> <a href="/sg/en/home/brands/patheon.html" onclick="" id="footer-link-5-7" data-analytics-section="footer" data-analytics-container="Our Portfolio" data-analytics-text="Patheon">Patheon <span></span> </a> </li> <li> <a href="/sg/en/home/brands/ppd.html" onclick="" id="footer-link-5-8" data-analytics-section="footer" data-analytics-container="Our Portfolio" data-analytics-text="PPD">PPD <span></span> </a> </li> </ul> </div> </div> </div> <div class="footer-legal"> <div class="footer-legal-container"> <div class="footer-legal-link "> <div class="footer-legal-logo"> <svg id="Layer_1" data-name="Layer 1" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 485.52 223.55"> <defs> <style> .tf-logo-cls-1 { fill: #ee3134; } .tf-logo-cls-2 { fill: #fff; } </style> </defs> <rect class="tf-logo-cls-1" width="485.52" height="223.55"/> <path class="tf-logo-cls-2" d="M108.27,83.11V76h-32v7.13h11v31h9.92v-31Zm123.5,31c-.26-2.53-.42-4.49-.42-5.81V95.46c0-5.33-3.91-8.65-9.08-8.65a10.21,10.21,0,0,0-8.82,4.69c-1.11-3-4.38-4.54-7.44-4.54-3.7,0-6.81,1.22-8.55,4.54l-.22-4h-9.07V114.1h9.39v-16c0-.84-.37-5.38,4-5.38,2.91,0,3.59,2.59,3.59,5.12V114.1h9.34v-16c0-.84-.37-5.38,4-5.38,2.91,0,3.6,2.59,3.6,5.12V114.1ZM186,95.35V87.28c-4.07,0-7.18,1.27-8.39,5.33l-.22-5.07H168c.21,2.17.21,5.07.21,6.82V114.1h9.4V102.48c0-4.38,1.26-7.07,6.44-7.17.63,0,1.26,0,1.95,0m62-8.54c-8.66,0-14.31,4.8-14.31,13.93,0,9.4,5.71,14.1,14.31,14.1s14.31-4.7,14.31-14.1c0-9.13-5.65-13.93-14.31-13.93m0,5.59c4,0,4.7,4.06,4.7,8.23,0,4.86-.85,8.66-4.7,8.66s-4.7-3.8-4.7-8.66c0-4.22.74-8.28,4.7-8.28ZM137.21,114.1a57.55,57.55,0,0,1-.37-5.81V95.46c0-5.33-4-8.65-9.13-8.65a11.12,11.12,0,0,0-4.44.84,9.58,9.58,0,0,0-3.38,2.69V76H110.5V114.1h9.39v-16c0-.84-.36-5.38,4-5.38,3,0,3.59,2.59,3.59,5.12V114.1Zm28.72-11.46c0-9.55-2.8-15.83-13.41-15.83-8.39,0-13.41,5.17-13.41,13.25,0,9.92,3.54,14.78,13.88,14.78a14.49,14.49,0,0,0,8.24-2.22,9.58,9.58,0,0,0,4.49-7.29h-8.87a4.15,4.15,0,0,1-4.49,4.07c-3.59,0-4.32-3.43-4.27-6.76Zm-9-5.12h-8.71c.21-2.8.84-5.65,4.32-5.8a3.49,3.49,0,0,1,3.33,1.84,7.36,7.36,0,0,1,1.06,4Z"/> <path class="tf-logo-cls-2" d="M409.29,94.88V86.81c-4.06-.06-7.18,1.26-8.39,5.33l-.21-4.6H391.3c.2,2.17.2,5.07.2,6.81v19.74h9.4V102.48c0-4.38,1.27-7.54,6.44-7.65.63,0,1.26,0,2,0m-48.87,19.21a54.56,54.56,0,0,1-.37-5.8V95.47c0-5.34-4-8.66-9.13-8.66a10.52,10.52,0,0,0-4.33.84,9.73,9.73,0,0,0-3.49,2.69V76h-9.39v38.11h9.39v-16c0-.84-.37-5.38,4-5.38,2.95,0,3.59,2.58,3.59,5.12v16.25Zm-29-7.91c0-4.12-2.16-6.12-5.17-7.23-5.65-2-9.88-2.11-9.88-4.23a2.24,2.24,0,0,1,2.44-2.48,3.34,3.34,0,0,1,2.52.85,3.7,3.7,0,0,1,.69,2.53h8.92c-.21-7-5.7-8.81-11.72-8.81-5.12,0-11.76,1.79-11.76,8.18,0,9.29,15,6.86,15,11.82,0,1.75-1.43,2.53-3.28,2.53a2.92,2.92,0,0,1-2.42-1.26,3.36,3.36,0,0,1-.58-2.59h-9c-.16,7.92,5.7,9.35,12.19,9.35,6.08,0,12-2.22,12-8.66m57.78-3.54c.06-9.55-2.79-15.83-13.41-15.83-8.39,0-13.41,5.17-13.41,13.25,0,9.92,3.54,14.78,13.89,14.78a14.56,14.56,0,0,0,8.23-2.22,9.52,9.52,0,0,0,4.49-7.29H380.1a4.14,4.14,0,0,1-4.48,4.07c-3.59,0-4.33-3.43-4.28-6.76Zm-9-5.12H371.5c.21-2.8.84-5.65,4.33-5.8a3.51,3.51,0,0,1,3.33,1.85,7.38,7.38,0,0,1,1,4Zm-75.39-10h-9.39V114.1h9.39ZM292.5,83l2.22-7H269.47v38.11h9.92v-15h8l2.21-7H279.39V83Zm12.32,0,2.23-7h-9.29l-2.22,7Z"/> <path class="tf-logo-cls-2" d="M162.45,125.26h3.44v21.61h-3.44Zm232,22c-7.21,0-12.59-4-12.59-11s6-11.42,12.81-11.42a13.4,13.4,0,0,1,6.78,1.9l-1.77,2.09a10.44,10.44,0,0,0-5-1.41,9,9,0,0,0-6.85,2.64,8.89,8.89,0,0,0-2.18,6.33,7.9,7.9,0,0,0,2.56,6.3c1.65,1.63,4.18,2.08,6.66,2.08a12.1,12.1,0,0,0,5.46-1.55l1.68,2a14.64,14.64,0,0,1-7.59,2m-36.24-22h3.44v21.61h-3.44Zm-77.92,2.58h-8.05v19h-3.36v-19h-8v-2.58h19.77ZM100.78,146.1a13.66,13.66,0,0,1-6.09,1.22A20.13,20.13,0,0,1,86,145.37l1.43-2.45a16.3,16.3,0,0,0,7.54,1.82,7.65,7.65,0,0,0,3.93-.88,3.14,3.14,0,0,0,1.9-2.79c0-1.81-1.39-2.93-4.73-3.71l-3.51-.82c-3.5-.82-5.7-3-5.7-5.56,0-3.68,3.62-6.29,8.78-6.29a16.39,16.39,0,0,1,8.29,2.06L102.33,129a13.46,13.46,0,0,0-6.55-1.73c-3.07,0-5.2,1.19-5.2,3.22,0,1.56,1.3,2.49,4.31,3.22l3.25.78a11.33,11.33,0,0,1,4.78,2.18,5.38,5.38,0,0,1,1.68,3.86,6.4,6.4,0,0,1-3.82,5.57m138.41.77-8.58-11.52c-1.61-2.16-4.33-6.38-4.33-6.38s.3,3.65.32,6.85l.09,11.05h-3.43V125.26h4.09L236,137c1.69,2.29,4,5.92,4,5.92s-.52-4-.54-6.84l-.08-10.85h3.4v21.61Zm59.2-21.61h3.45v21.61h-3.45Zm41,2.54H327.56v6.4h10v2.54h-10v10.13h-3.45V125.26h15.76ZM188.17,146.87V125.26H204.1l-.46,2.58h-12v6.44h10.24v2.58h-10.2v7.3h12.86v2.71Zm-52.36.37c-7.2,0-12.58-4-12.58-11s6-11.42,12.8-11.42a13.4,13.4,0,0,1,6.78,1.9l-1.76,2.09a10.44,10.44,0,0,0-5-1.41,9,9,0,0,0-6.86,2.64,8.89,8.89,0,0,0-2.18,6.33,7.9,7.9,0,0,0,2.57,6.3c1.65,1.63,4.17,2.08,6.65,2.08a12.1,12.1,0,0,0,5.46-1.55l1.68,2a14.59,14.59,0,0,1-7.59,2"/> </svg> </div> <div class="footer-legal-list"> <ul class="footer-legal-list"> <li class=""> <a href="/sg/en/home/global/terms-and-conditions.html" id="hfTermsOfServiceLink" data-analytics-section="footer" data-analytics-container="legal" data-analytics-text="Terms & Conditions">Terms & Conditions</a> </li> <li class=""> <a href="/sg/en/home/global/privacy-policy.html" id="hfPrivacyPolicyLink" data-analytics-section="footer" data-analytics-container="legal" data-analytics-text="Privacy Policy">Privacy Policy</a> </li> <li class=""> <a href="/sg/en/home/global/online-pricing-policy.html" id="hfOnlinePricePolicyLink" data-analytics-section="footer" data-analytics-container="legal" data-analytics-text="Price & Freight Policy">Price & Freight Policy</a> </li> <li> <div id="teconsent"></div> <div id="consent_blackbar"></div> </li> </ul> <div class="all-rights">© 2006-2024 Thermo Fisher Scientific Inc. All rights reserved. All trademarks are the property of Thermo Fisher Scientific and its subsidiaries unless otherwise specified.</div> </div> <style> .test-svg { font-size: 14px; } </style> <div class="footer-legal-country"> <div class="country-flag"> <img class="country-flag-img" src="/store/global-header-footer-static/global/images/flags/sg.gif" alt="Singapore flag icon" data-uw-rm-ima-original="Singapore flag icon"> </div> <div class="country-name">Singapore</div> </div> </div>  <script type="text/javascript"> if(document.getElementById('language-select')){ var myOpts = document.getElementById('language-select').options; for(var i = 0; i < myOpts.length; i++){ if((window.location.pathname.split("/")[2] == myOpts[i].value) || (getCookie('CK_LANG_CODE') == myOpts[i].value)){ myOpts[i].setAttribute("selected", "selected"); } } } </script> </div> </div> <script> // DTM footer init if ( window._satellite && window._satellite.pageBottom ) { window._satellite.pageBottom(); } </script> <script> /* START: Global header promo config */ // var globalHeaderPromoConfig = { // "Promos": [ // { // "Text":"Ordering online is fast & simple.", // "LinkText":"Register today", // "ISO": "us ca", //use this if you need to restrict to an iso // "LANG": "en", //use this if you need to restrict to a certain language // "URL": "/auth/create-account&ICID=L0-HP-TB-EBIZ-RS001-registeronline-20160921-SG", // "URLAppendISO": false //If using an ICID, you can use this to have the current ISO automatically appended // } // ], // "Config": { // 'HideDisplayTypes':'B2B SCMS' // } // }; /* END: Global header promo config */ /* START: Global Header Promo Display Logic */ // function initGlobalHeaderPromo(){ // if ( typeof(globalHeaderPromoConfig) === 'object' ) { // $('.global-promo').remove(); //Do not display promo for B2B. You can change these display types in the config file. // var hideDisplayTypes = globalHeaderPromoConfig.Config.HideDisplayTypes.split(" "); // for( var i=0; i< hideDisplayTypes.length;i++){ // if ( _lt.displayTypeMatch( hideDisplayTypes[i]) ) return false; // } //Ok Usertype? Let's go for it, then... Let's loop through our promos and see if they can be displayed for this user // for ( var promoKey in globalHeaderPromoConfig.Promos ) { // var thisPromo = globalHeaderPromoConfig.Promos[promoKey]; // if ( thisPromo.ISO && !_lt.displayIsoMatch( thisPromo.ISO ) ) continue; // if ( thisPromo.LANG && !_lt.displayLangMatch( thisPromo.LANG ) ) continue; //Append the current user's ISO code to the end of the URL ( for tracking ) // if ( thisPromo.URLAppendISO && thisPromo.URLAppendISO !== false ) { // thisPromo.URL = thisPromo.URL+'-'+_lt.user.displayIso; // } // if ( window.messagingBar ) window.messagingBar.addPromo(thisPromo.Text,thisPromo.LinkText,thisPromo.URL); //Promo displayed - let's return true // return true; // } //Promo Loop // } //Config Check //Promo did not display.. Return false. // return false; // } // $(document).ready(initGlobalHeaderPromo) ; /* END: Global Header Promo Display Logic */ </script>  <style> /* turn bar red - THIS IS ONLY for emergencies */ /* #messagingBar.messaging-bar-promos { background: #ee3134; }*/ /* #messagingBarClose{display:none !important } */ </style>  <style> @media(min-width: 980px) { .template-2-column .mondrian-module-f { height: auto !important; } .mondrian-featured-list { display: table; height: 100%; margin: 0; padding: 0; position: relative; width: 100%; } .mondrian-module-list ul li, .mondrian-module-list ul.default li, .mondrian-module-list ul.mondrian-featured-list li { display: table-row !important; border-bottom: 1px solid #fff !important; border-bottom-width: 1px !important; border-bottom-style: solid !important; border-bottom-color: rgb(255, 255, 255) !important; word-break: normal !important; } } @media(min-width:767px) { .mondrian-module-list ul li, .mondrian-module-list ul.default li, .mondrian-module-list ul.mondrian-featured-list li { display: table-row!important; border-bottom: 1px solid #fff !important; word-break: normal !important; } } </style> </div>    <script type="text/javascript"> window.performance && window.performance.mark && window.performance.mark("globalFooter:renderEnd"); </script> <script id="localizedCountriesInfoURL" type="text/javascript"> var ltCountryInfo = {"af":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/af.gif","name":"Afghanistan","phone":"\t<a href='/af/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"al":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/al.gif","name":"Albania","phone":"<a href='/al/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"https://eu.fishersci.com/eu/","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"dz":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/dz.gif","name":"Algeria","phone":"<a href='/dz/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"ad":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/ad.gif","name":"Andorra","phone":"<a href='/ad/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"ao":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/ao.gif","name":"Angola","phone":"<a href='/ao/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"aq":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/emptyflag.gif","name":"Antarctica","phone":"<a href='/aq/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":true,"registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"LATAM_Others"},"ag":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/ag.gif","name":"Antigua and Barbuda","phone":"<a href='/ag/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"ar":{"defaultLanguage":"es","flag":"/shared-static/images/icons/flags/ar.gif","name":"Argentina","phone":"<a href='/ar/en/home/technical-resources/contact-us.html'>Contacto</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"LATAM_AR"},"aw":{"defaultLanguage":"en","name":"Aruba","phone":"<a href='/aw/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"am":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/am.gif","name":"Armenia","phone":"<a href='/am/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"au":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/au.gif","name":"Australia","phone":"<a href='/au/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brandGroup":"2","groupDisplay":"","regionMapping":"IPAC_AA"},"at":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/at.gif","name":"Austria","phone":"<a href='/at/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":true,"brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"https://eu.fishersci.com/eu/","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"EMEA"},"az":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/az.gif","name":"Azerbaijan","phone":"<a href='/az/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"bs":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/bs.gif","name":"Bahamas","phone":"<a href='/bs/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":true,"euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"LATAM_Others"},"bh":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/bh.gif","name":"Bahrain","phone":"<a href='/bh/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":true,"brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"bd":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/bd.gif","name":"Bangladesh","phone":"<a href='/bd/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"2","groupDisplay":"","regionMapping":"IPAC_SA"},"bb":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/bb.gif","name":"Barbados","phone":"<a href='/bb/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":true,"euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"LATAM_Others"},"by":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/by.gif","name":"Belarus","phone":"<a href='/by/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"https://eu.fishersci.com/eu/","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"be":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/be.gif","name":"Belgium","phone":"<a href='/be/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":true,"brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"https://eu.fishersci.com/eu/","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"EMEA"},"bz":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/bz.gif","name":"Belize","phone":"<a href='/bz/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":true,"euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"LATAM_Others"},"bj":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/bj.gif","name":"Benin","phone":"<a href='/bj/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"bm":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/bm.gif","name":"Bermuda","phone":"<a href='/bm/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":true,"euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"LATAM_Others"},"bt":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/bt.gif","name":"Bhutan","phone":"<a href='/in/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"IPAC_SA"},"bo":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/bo.gif","name":"Bolivia","phone":"<a href='/bo/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":true,"euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"LATAM_Others"},"ba":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/ba.gif","name":"Bosnia and Herzegovina","phone":"<a href='/ba/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"https://eu.fishersci.com/eu/","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"bw":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/bw.gif","name":"Botswana","phone":"<a href='/bw/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"bv":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/bv.gif","name":"Bouvet Island","phone":"<a href='/bv/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"br":{"defaultLanguage":"pt","flag":"/shared-static/images/icons/flags/br.gif","name":"Brasil","phone":"<a href='/br/en/home/technical-resources/contact-us.html'>Contato</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"LATAM_BR"},"bn":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/bn.gif","name":"Brunei Darussalam","phone":"<a href='/bn/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"2","groupDisplay":"","regionMapping":"IPAC_SEA"},"bg":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/bg.gif","name":"Bulgaria","phone":"<a href='/bg/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"https://eu.fishersci.com/eu/","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"bf":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/bf.gif","name":"Burkina Faso","phone":"<a href='/bf/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"bi":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/bi.gif","name":"Burundi","phone":"<a href='/bi/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"kh":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/kh.gif","name":"Cambodia","phone":"<a href='/kh/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"2","groupDisplay":"","regionMapping":"IPAC_SEA"},"cm":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/cm.gif","name":"Cameroon","phone":"<a href='/cm/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"ca":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/ca.gif","name":"Canada","phone":"<a href='/ca/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","quickLinkIndex":"1","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.ca","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"NA"},"ic":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/ic.gif","name":"Canary Islands","phone":"<a href='/ic/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"cv":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/cv.gif","name":"Cape Verde","phone":"<a href='/cv/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"ky":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/ky.gif","name":"Cayman Islands","phone":"<a href='/ky/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"cf":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/cf.gif","name":"Central African Republic","phone":"<a href='/cf/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"td":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/td.gif","name":"Chad","phone":"<a href='/td/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"cl":{"defaultLanguage":"es","flag":"/shared-static/images/icons/flags/cl.gif","name":"Chile","phone":"<a href='/cl/en/home/technical-resources/contact-us.html'>Contacto</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"LATAM_CL"},"cn":{"defaultLanguage":"zh","flag":"/shared-static/images/icons/flags/cn.gif","name":"China | 中国","phone":"<a href='/cn/en/home/technical-resources/contact-us.html'>联系我们</a>","signInHidden":"","registerHidden":"","euCountry":"","quickLinkIndex":"2","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brandGroup":"1","groupDisplay":"","regionMapping":"GC_CN"},"co":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/co.gif","name":"Colombia","phone":"<a href='/co/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"LATAM_Others"},"km":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/km.gif","name":"Comoros","phone":"<a href='/km/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"cg":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/cg.gif","name":"Congo","phone":"<a href='/cg/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":" Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"cd":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/cd.gif","name":"Congo (Democratic Republic of)","phone":"<a href='/cd/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":true,"euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"cr":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/cr.gif","name":"Costa Rica","phone":"<a href='/cr/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"LATAM_Others"},"ci":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/ci.gif","name":"Cote Dlvoire (Ivory Coast)","phone":"<a href='/ci/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"hr":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/hr.gif","name":"Croatia (Hrvatska)","phone":"<a href='/hr/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":true,"brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"https://eu.fishersci.com/eu/","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"cw":{"defaultLanguage":"en","name":"Curaçao","phone":"<a href='/cw/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":true,"registerHidden":true,"euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"LATAM_Others"},"cy":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/cy.gif","name":"Cyprus","phone":"<a href='/cy/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":true,"brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"cz":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/cz.gif","name":"Czech Republic","phone":"<a href='/cz/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":true,"brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"https://eu.fishersci.com/eu/","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"EMEA"},"dk":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/dk.gif","name":"Denmark","phone":"<a href='/dk/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":true,"brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"https://eu.fishersci.com/eu/","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"EMEA"},"dj":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/dj.gif","name":"Djibouti","phone":"<a href='/dj/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"dm":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/dm.gif","name":"Dominica","phone":"<a href='/dm/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"LATAM_Others"},"do":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/do.gif","name":"Dominican Republic","phone":"<a href='/do/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"LATAM_Others"},"ec":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/ec.gif","name":"Ecuador","phone":"<a href='/ec/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"LATAM_Others"},"eg":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/eg.gif","name":"Egypt","phone":"<a href='/eg/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":true,"brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services ","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"sv":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/sv.gif","name":"El Salvador","phone":"<a href='/sv/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"LATAM_Others"},"er":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/er.gif","name":"Eritrea","phone":"<a href='/er/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"ee":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/ee.gif","name":"Estonia","phone":"<a href='/ee/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":true,"brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"https://eu.fishersci.com/eu/","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"et":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/et.gif","name":"Ethiopia","phone":"<a href='/et/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"fo":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/fo.gif","name":"Faroe Islands","phone":"<a href='/fo/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"fj":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/fj.gif","name":"Fiji","phone":"<a href='/fj/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":true,"euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"2","groupDisplay":"","regionMapping":"IPAC_AA"},"fi":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/fi.gif","name":"Finland","phone":"<a href='/fi/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":true,"brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"https://eu.fishersci.com/eu/","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"EMEA"},"fr":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/fr.gif","name":"France Metropolitan","phone":"<a href='/fx/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":true,"brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"gf":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/gf.gif","name":"French Guyana","phone":"<a href='/gf/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":true,"euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"LATAM_Others"},"pf":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/pf.gif","name":"French Polynesia","phone":"<a href='/pf/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"IPAC_AA"},"ga":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/ga.gif","name":"Gabon","phone":"<a href='/ga/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"gm":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/gm.gif","name":"Gambia","phone":"<a href='/gm/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"ge":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/ge.gif","name":"Georgia","phone":"<a href='/ge/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"de":{"defaultLanguage":"de","flag":"/shared-static/images/icons/flags/de.gif","name":"Germany | Deutschland","phone":"<a href='/de/en/home/technical-resources/contact-us.html'>Kontaktieren Sie uns</a>","signInHidden":"","registerHidden":"","euCountry":true,"quickLinkIndex":"3","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"https://eu.fishersci.com/eu/","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"EMEA"},"gh":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/gh.gif","name":"Ghana","phone":"<a href='/gh/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"gi":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/gi.gif","name":"Gibraltar","phone":"<a href='/gi/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":true,"euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"EMEA"},"gr":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/gr.gif","name":"Greece","phone":"<a href='/gr/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":true,"brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"https://eu.fishersci.com/eu/","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"gl":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/gl.gif","name":"Greenland","phone":"<a href='/gl/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":true,"registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"gd":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/gd.gif","name":"Grenada","phone":"<a href='/gd/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"LATAM_Others"},"gp":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/gp.gif","name":"Guadeloupe","phone":"<a href='/gp/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"LATAM_Others"},"gu":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/gu.gif","name":"Guam","phone":"<a href='/gu/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"IPAC_SEA"},"gt":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/gt.gif","name":"Guatemala","phone":"<a href='/gt/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"LATAM_Others"},"gn":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/gn.gif","name":"Guinea","phone":"<a href='/gn/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"gy":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/gy.gif","name":"Guyana","phone":"<a href='/gy/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"LATAM_Others"},"ht":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/ht.gif","name":"Haiti","phone":"<a href='/ht/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"LATAM_Others"},"hn":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/hn.gif","name":"Honduras","phone":"<a href='/hn/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"LATAM_Others"},"hk":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/cn.gif","name":"Hong Kong","phone":"<a href='/tw/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"GC"},"hu":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/hu.gif","name":"Hungary","phone":"<a href='/hu/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":true,"brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"https://eu.fishersci.com/eu/","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"EMEA"},"is":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/is.gif","name":"Iceland","phone":"<a href='/is/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":true,"brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"in":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/in.gif","name":"India","phone":"<a href='/in/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","quickLinkIndex":"4","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.in","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"2","groupDisplay":"","regionMapping":"IPAC_SA"},"id":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/id.gif","name":"Indonesia","phone":"<a href='/id/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"2","groupDisplay":"","regionMapping":"IPAC_SEA"},"iq":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/iq.gif","name":"Iraq","phone":"<a href='/iq/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"ie":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/ie.gif","name":"Ireland","phone":"<a href='/ie/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":true,"brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"https://eu.fishersci.com/eu/","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"il":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/il.gif","name":"Israel","phone":"<a href='/il/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":true,"brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"it":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/it.gif","name":"Italy","phone":"<a href='/it/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":true,"brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"https://eu.fishersci.com/eu/","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"EMEA"},"jm":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/jm.gif","name":"Jamaica","phone":"<a href='/jm/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"LATAM_Others"},"jp":{"defaultLanguage":"ja","flag":"/shared-static/images/icons/flags/jp.gif","name":"Japan | 日本","phone":"<a href='/jp/en/home/technical-resources/contact-us.html'>お問い合わせ</a>","signInHidden":"","registerHidden":"","euCountry":"","quickLinkIndex":"5","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"/jp/ja/home/brands/fisher-scientific.html","brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"JP"},"jo":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/jo.gif","name":"Jordan","phone":"<a href='/jo/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":true,"brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"kz":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/kz.gif","name":"Kazakhstan","phone":"<a href='/kz/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"ke":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/ke.gif","name":"Kenya","phone":"<a href='/ke/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":true,"brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"kr":{"defaultLanguage":"ko","flag":"/shared-static/images/icons/flags/kr.gif","name":"Korea | 대한민국","phone":"<a href='/kr/en/home/technical-resources/contact-us.html'>연락처</a>","signInHidden":"","registerHidden":"","euCountry":true,"brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"/content/lifetech/global/en/home/brands/fisher-scientific","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"IPAC_KR"},"kw":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/kw.gif","name":"Kuwait","phone":"<a href='/kw/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":true,"brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"kg":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/kg.gif","name":"Kyrgyzstan","phone":"<a href='/kg/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"la":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/la.gif","name":"Laos","phone":"<a href='/la/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"IPAC_SEA"},"lv":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/lv.gif","name":"Latvia","phone":"<a href='/lv/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":true,"brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"https://eu.fishersci.com/eu/","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"lb":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/lb.gif","name":"Lebanon","phone":"<a href='/lb/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":true,"brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"ls":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/ls.gif","name":"Lesotho","phone":"<a href='/ls/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"defaultcountry":{"defaultLanguage":"en","name":"Default Country","phone":"","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"groupDisplay":""},"lr":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/lr.gif","name":"Liberia","phone":"<a href='/lr/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"ly":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/ly.gif","name":"Libya","phone":"<a href='/ly/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"li":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/li.gif","name":"Liechtenstein","phone":"<a href='/li/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":true,"euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":" Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"EMEA"},"lt":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/lt.gif","name":"Lithuania","phone":"<a href='/lt/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":true,"brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"https://eu.fishersci.com/eu/","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"lu":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/lu.gif","name":"Luxembourg","phone":"<a href='/lu/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":true,"euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"https://eu.fishersci.com/eu/","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"EMEA"},"mo":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/cn.gif","name":"Macau","phone":"<a href='/mo/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":true,"euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"mk":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/mk.gif","name":"Macedonia","phone":"<a href='/mk/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"https://eu.fishersci.com/eu/","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"mg":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/mg.gif","name":"Madagascar","phone":"<a href='/mg/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"mw":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/mw.gif","name":"Malawi","phone":"<a href='/mw/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"my":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/my.gif","name":"Malaysia","phone":"<a href='/my/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com.my","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"2","groupDisplay":"","regionMapping":"IPAC_SEA"},"mv":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/mv.gif","name":"Maldives","phone":"<a href='/mv/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"2","groupDisplay":"","regionMapping":"IPAC_SA"},"ml":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/ml.gif","name":"Mali","phone":"<a href='/ml/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"mt":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/mt.gif","name":"Malta","phone":"<a href='/mt/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":true,"brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"mq":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/mq.gif","name":"Martinique","phone":"<a href='/mq/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"LATAM_Others"},"mr":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/mr.gif","name":"Mauritania","phone":"<a href='/mr/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"mu":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/mu.gif","name":"Mauritius","phone":"<a href='/mu/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":true,"brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"yt":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/yt.gif","name":"Mayotte","phone":"<a href='/yt/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"mx":{"defaultLanguage":"es","flag":"/shared-static/images/icons/flags/mx.gif","name":"México","phone":"<a href='/mx/en/home/technical-resources/contact-us.html'>Contacto</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"LATAM_MX"},"md":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/md.gif","name":"Moldova","phone":"<a href='/md/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"https://eu.fishersci.com/eu/","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"mc":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/mc.gif","name":"Monaco","phone":"<a href='/mc/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":true,"euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"EMEA"},"mn":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/mn.gif","name":"Mongolia","phone":"<a href='/mn/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"me":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/me.gif","name":"Montenegro","phone":"<a href='/me/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"ms":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/ms.gif","name":"Montserrat","phone":"<a href='/ms/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":true,"registerHidden":true,"euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"LATAM_Others"},"ma":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/ma.gif","name":"Morocco","phone":"<a href='/ma/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"mz":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/mz.gif","name":"Mozambique","phone":"<a href='/mz/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"mm":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/mm.gif","name":"Myanmar","phone":"<a href='/mm/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"2","groupDisplay":"","regionMapping":"IPAC_SEA"},"na":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/na.gif","name":"Namibia","phone":"<a href='/na/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"np":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/np.gif","name":"Nepal","phone":"<a href='/np/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"2","groupDisplay":"","regionMapping":"IPAC_SA"},"nl":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/nl.gif","name":"Netherlands","phone":"<a href='/nl/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":true,"brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"https://eu.fishersci.com/eu/","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"EMEA"},"nc":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/nc.gif","name":"New Caledonia","phone":"<a href='/nc/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"2","groupDisplay":""},"nz":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/nz.gif","name":"New Zealand (Aotearoa)","phone":"<a href='/nz/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brandGroup":"2","groupDisplay":"","regionMapping":"IPAC_AA"},"ni":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/ni.gif","name":"Nicaragua","phone":"<a href='/ni/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"LATAM_Others"},"ne":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/ne.gif","name":"Niger","phone":"<a href='/ne/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"ng":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/ng.gif","name":"Nigeria","phone":"<a href='/ng/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"no":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/no.gif","name":"Norway","phone":"<a href='/no/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":true,"brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"https://eu.fishersci.com/eu/","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"EMEA"},"om":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/om.gif","name":"Oman","phone":"<a href='/om/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":true,"brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"pk":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/pk.gif","name":"Pakistan","phone":"<a href='/pk/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"2","groupDisplay":""},"ps":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/ps.gif","name":"Palestine","phone":"<a href='/ps/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"pa":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/pa.gif","name":"Panamá","phone":"<a href='/pa/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"LATAM_Others"},"pg":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/pg.gif","name":"Papua New Guinea","phone":"<a href='/pg/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":true,"euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"2","groupDisplay":"","regionMapping":"IPAC_AA"},"py":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/py.gif","name":"Paraguay","phone":"<a href='/py/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"LATAM_Others"},"pe":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/pe.gif","name":"Perú","phone":"<a href='/pe/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"LATAM_Others"},"ph":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/ph.gif","name":"Philippines","phone":"<a href='/ph/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":true,"registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"2","groupDisplay":"","regionMapping":"IPAC_SEA"},"pl":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/pl.gif","name":"Poland","phone":"<a href='/pl/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":true,"brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"https://eu.fishersci.com/eu/","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"EMEA"},"pt":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/pt.gif","name":"Portugal","phone":"<a href='/pt/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":true,"brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"https://eu.fishersci.com/eu/","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"EMEA"},"pr":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/pr.gif","name":"Puerto Rico","phone":"<a href='/pr/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"LATAM_Others"},"qa":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/qa.gif","name":"Qatar","phone":"<a href='/qa/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":true,"brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"re":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/re.gif","name":"Reunion","phone":"<a href='/re/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"ro":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/ro.gif","name":"Romania","phone":"<a href='/ro/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":true,"brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"https://eu.fishersci.com/eu/","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"ru":{"defaultLanguage":"ru","flag":"/shared-static/images/icons/flags/ru.gif","name":"Russia | Россия","phone":"<a href='/ru/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"https://eu.fishersci.com/eu/","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"rw":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/rw.gif","name":"Rwanda","phone":"<a href='/rw/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"gs":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/gs.gif","name":"S. Georgia and S. Sandwich Isls.","phone":"<a href='/gs/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"kn":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/kn.gif","name":"Saint Kitts and Nevis","phone":"<a href='/kn/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"lc":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/lc.gif","name":"Saint Lucia","phone":"<a href='/lc/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"vc":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/vc.gif","name":"Saint Vincent and the Grenadines","phone":"<a href='/vc/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"sm":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/sm.gif","name":"San Marino","phone":"<a href='/sm/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"st":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/st.gif","name":"Sao Tome and Principe","phone":"<a href='/st/en/home/technical-resources/contact-us.html?supportType=OS#ordersupport'>Order Support</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"sa":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/sa.gif","name":"Saudi Arabia","phone":"<a href='/sa/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":true,"brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"sn":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/sn.gif","name":"Senegal","phone":"<a href='/sn/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"rs":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/rs.gif","name":"Serbia","phone":"<a href='/rs/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"https://eu.fishersci.com/eu/","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"sc":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/sc.gif","name":"Seychelles","phone":"<a href='/sc/en/home/technical-resources/contact-us.html?supportType=OS#ordersupport'>Order Support</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"sl":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/sl.gif","name":"Sierra Leone","phone":"<a href='/sl/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"sg":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/sg.gif","name":"Singapore","phone":"<a href='/sg/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"http://myfisherstore.com/singapore/","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"2","groupDisplay":"","regionMapping":"IPAC_SP"},"sk":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/sk.gif","name":"Slovak Republic","phone":"<a href='/sk/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"https://eu.fishersci.com/eu/","brand4openLinkInNewWindow":true,"brand5linkText":" Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"EMEA"},"si":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/si.gif","name":"Slovenia","phone":"<a href='/si/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":true,"brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"so":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/so.gif","name":"Somalia","phone":"<a href='/so/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":true,"euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"za":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/za.gif","name":"South Africa","phone":"<a href='/za/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":true,"brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"es":{"defaultLanguage":"es","flag":"/shared-static/images/icons/flags/es.gif","name":"Spain","phone":"<a href='/es/en/home/technical-resources/contact-us.html'>Contáctenos</a>","signInHidden":"","registerHidden":"","euCountry":true,"brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"https://eu.fishersci.com/eu/","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"EMEA"},"lk":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/lk.gif","name":"Sri Lanka","phone":"<a href='/lk/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"2","groupDisplay":"","regionMapping":"IPAC_SA"},"sh":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/sh.gif","name":"St. Helena","phone":"<a href='/sh/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"sr":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/sr.gif","name":"Suriname","phone":"<a href='/sr/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"LATAM_Others"},"sj":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/sj.gif","name":"Svalbard and Jan Mayen Islands","phone":"<a href='/sj/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"sz":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/sz.gif","name":"Swaziland","phone":"<a href='/sz/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"se":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/se.gif","name":"Sweden","phone":"<a href='/se/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":true,"brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"https://eu.fishersci.com/eu/","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"EMEA"},"ch":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/ch.gif","name":"Switzerland","phone":"<a href='/ch/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":true,"brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"https://eu.fishersci.com/eu/","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"EMEA"},"sy":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/sy.gif","name":"Syria","phone":"<a href='/sy/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":true,"registerHidden":true,"euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"tw":{"defaultLanguage":"zt","name":"Taiwan | 台灣","phone":"<a href='/tw/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"2","groupDisplay":"","regionMapping":"IPAC_TW"},"tj":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/tj.gif","name":"Tajikistan","phone":"<a href='/tj/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"tz":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/tz.gif","name":"Tanzania","phone":"<a href='/tz/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"th":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/th.gif","name":"Thailand","phone":"<a href='/th/en/home/technical-resources/contact-us.html?supportType=OS#ordersupport'>Order Support</a>","signInHidden":true,"registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"2","groupDisplay":"","regionMapping":"IPAC_SEA"},"tg":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/tg.gif","name":"Togo","phone":"<a href='/tg/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"to":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/to.gif","name":"Tonga","phone":"<a href='/to/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":true,"registerHidden":true,"euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"IPAC_AA"},"tt":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/tt.gif","name":"Trinidad and Tobago","phone":"<a href='/tt/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"LATAM_Others"},"tn":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/tn.gif","name":"Tunisia","phone":"<a href='/tn/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":true,"brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"tr":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/tr.gif","name":"Turkey","phone":"<a href='/tr/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":true,"brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"https://eu.fishersci.com/eu/","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"tm":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/tm.gif","name":"Turkmenistan","phone":"<a href='/tm/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"tc":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/tc.gif","name":"Turks and Caicos Islands","phone":"<a href='/tc/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"ug":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/ug.gif","name":"Uganda","phone":"<a href='/ug/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"ua":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/ua.gif","name":"Ukraine","phone":"<a href='/ua/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"https://eu.fishersci.com/eu/","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"ae":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/ae.gif","name":"United Arab Emirates","phone":"<a href='/ae/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":true,"brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"uk":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/gb.gif","name":"United Kingdom","phone":"<a href='/uk/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":true,"quickLinkIndex":"6","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"https://eu.fishersci.com/eu/","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"EMEA"},"us":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/us.gif","name":"United States","signInHidden":"","registerHidden":"","euCountry":"","quickLinkIndex":"7","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar3.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"//www.unitylabservices.com","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"NA"},"um":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/um.gif","name":"United States Minor Outlying Islands","phone":"<a href='/um/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":true,"registerHidden":true,"euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"LATAM_Others"},"uy":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/uy.gif","name":"Uruguay","phone":"<a href='/uy/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"LATAM_Others"},"uz":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/uz.gif","name":"Uzbekistan","phone":"<a href='/uz/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"va":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/va.gif","name":"Vatican City State (Holy See)","phone":"<a href='/va/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"ve":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/ve.gif","name":"Venezuela","phone":"<a href='/ve/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"LATAM_Others"},"vn":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/vn.gif","name":"Vietnam","phone":"<a href='/vn/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"2","groupDisplay":"","regionMapping":"IPAC_SEA"},"vg":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/vg.gif","name":"Virgin Islands (British)","phone":"<a href='/vg/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"vi":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/vi.gif","name":"Virgin Islands (U.S.)","phone":"<a href='/vi/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":"","regionMapping":"LATAM_Others"},"eh":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/eh.gif","name":"Western Sahara","phone":"<a href='/eh/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":true,"brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"ye":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/ye.gif","name":"Yemen","phone":"<a href='/ye/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"zm":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/zm.gif","name":"Zambia","phone":"<a href='/zm/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""},"zw":{"defaultLanguage":"en","flag":"/shared-static/images/icons/flags/zw.gif","name":"Zimbabwe","phone":"<a href='/zw/en/home/technical-resources/contact-us.html'>Contact Us</a>","signInHidden":"","registerHidden":"","euCountry":"","brandsImagePath":"/content/dam/LifeTech/Images/Header/brandbar.png","isGlobal":false,"brand1linkText":"Thermo Scientific","brand1linkURL":"/us/en/home/brands/thermo-scientific.html","brand2linkText":"Applied Biosystems","brand2linkURL":"/us/en/home/brands/applied-biosystems.html","brand3linkText":"Invitrogen","brand3linkURL":"/us/en/home/brands/invitrogen.html","brand4linkText":"Fisher Scientific","brand4linkURL":"//www.fishersci.com","brand4openLinkInNewWindow":true,"brand5linkText":"Unity Lab Services","brand5linkURL":"http://www.unitylabservices.com/","brand5openLinkInNewWindow":true,"brandGroup":"1","groupDisplay":""}}; </script> <script type="text/javascript" src="/store/global-header-footer-static/tf/js/footer-base.min.468bd07150dbbf.js" async></script> <script id="minicartScript" src="/store/minicartv3/minicart.js"></script> <script id="identityGlobal" src="/account-center/scripts/identityGlobal.min.js"></script>  <script data-inline-file-name='sec-assets-redirect.min.js' data-inline-site='tf'>/* Hash: 468bd07150dbbf Source: /tf/js/dist/sec-assets-redirect.min.js */ !function(e){let t=document.querySelectorAll("a[href^='https://sec-assets']");for(var n=0;n<t.length;n++)t[n].setAttribute("target","_blank"),t[n].addEventListener("click",function(t){t.preventDefault(),o(t,e(this))});function o(t,n){storageAssets=function(){var e,t,n,o=[],a={},s=0,i=document.getElementsByTagName("body")[0];function l(){if(0===s){if(!window.environmentURL)return!1;e="https://"+window.location.host,(t=!0)?(s=1,r()):(s=5,(n=document.createElement("iframe")).src=e+"/shared-static/support/_lt.localStorage.html",n.style.display="none",n.onload=function(){s=1,r()},n.onerror=function(){s=9},i.appendChild(n),window.attachEvent?window.attachEvent("message",d):window.addEventListener("message",d,!1))}}function d(e){if(e&&e.data&&"string"==typeof e.data){var t=e.data.split(":"),n=e.origin,o=decodeURIComponent(t[0]),s=decodeURIComponent(t[1]),i=(decodeURIComponent(t[2]),decodeURIComponent(t[3]));-1!==n.indexOf("thermofisher.")&&c(i,a[o+":"+s])}}function c(e,t){e?"lsFailure"===e&&(e=!1):e=null,t&&t(e)}function r(){for(var e,t=0;t<o.length;t++)u((e=o[t]).action,e.key,e.value,e.callback)}function u(i,d,r,u){if(l(),1!==s)o.push({action:i,key:d,value:r,callback:u});else if(t){var m=null;try{m=d&&r?window.localStorage[i](d,r):d?window.localStorage[i](d):window.localStorage[i]()}catch(e){m="lsFailure"}c(m,u)}else{var g="ls-"+i+":"+Math.floor(1e6*Math.random()+1),p=g;d&&(p+=":"+encodeURIComponent(d),r&&(p+=":"+encodeURIComponent(r))),a[g]=u,n.contentWindow.postMessage(p,e)}}return{getItem:function(e,t){u("getItem",e,null,t)},setItem:function(e,t,n){u("setItem",e,t,n)}}}();var o,a,s=window.location.hostname,i="/"+_lt.user.displayIso+"/"+_lt.user.displayLang+"/syndicated-content/snippets/terms-secure-file.html",l=s.split("thermofisher.")[1],d="https://"+s+"/api-gateway/tfdocs/signedurl?objectKey="+n.attr("href").split(l+"/")[1],c=localizedStrings.ACCEPTANCE||"Acceptance to Terms of Use",r=localizedStrings.BTN_AGREE||"Agree",u=localizedStrings.BTN_DISAGREE||"Disagree",m=localizedStrings.SUBMIT_ERROR_SERVER||"Error - please try again.";storageAssets.getItem("secureFileAccepted",function(n){if(_lt.user.isLoggedIn)if(e.ajax({type:"GET",url:d,dataType:"text",cache:!1,async:!1,success:function(e){try{o=JSON.parse(e)}catch(e){console.log("Error in Parsing Json File")}},error:function(e,t,n){},complete:function(){null!=o&&void 0!==o?a=o.success.preSignedURL:console.log("Error in getting presigned URL")}}),null!=n&&"Y"==n)window.open(a,"_blank"),_lt.user.initLoginChecks();else{var s=e('<div class="modal hide modal-loading modal-secure-file-acceptance"><div class="modal-header"><button type="button" class="close" data-dismiss="modal" aria-hidden="true">×</button><h3>'+c+'</h3></div><div class="modal-body"><div class="text-center"><span class="loading-wheel loading-wheel-md"></span></div></div><div class="modal-footer"><button type="button" class="btn btn-disagree" data-dismiss="modal">'+u+'</button><a href="'+a+'" target="_blank" class="btn btn-primary btn-agree">'+r+"</a></div></div>"),l=e(".modal-body",s);e(".btn-disagree",s),e(".btn-agree",s).click(function(){storageAssets.setItem("secureFileAccepted","Y"),s.modal("hide"),s.remove(),_lt.user.initLoginChecks()}),s.on("hidden",function(){s.remove()}),e.get(i).success(function(e){l.html(e),s.removeClass("modal-loading")}).error(function(e){l.text(m)}),s.appendTo("body"),s.modal({backdrop:"static",keyboard:!1}),s.modal("show"),e("body").append("<style>.modal-secure-file-acceptance.modal-loading .modal-footer { display:none; }</style>"),t.stopImmediatePropagation()}else invokeOidcLogin(window.location.href)})}}(window.$j);</script> <script type="text/javascript" id="dmOffers" src="/dm-offers/offers.min.js" defer></script> <script type="text/javascript"> var preferences = document.cookie.match(new RegExp("(^| )notice_preferences=([^;]+)")); var deployLaunch = ((preferences && parseInt(preferences[2] || 0) > 0) || (!true && !window.location.href.includes("eta=true"))); if (!document.querySelector("#tagmanager") && deployLaunch && !(/how-cookies-are-used|privacy-policy/i.test(window.location.href))) { var script = document.createElement("script"); script.id = "tagmanager"; script.src = "https://assets.adobedtm.com/launch-ENeecb77f1160a4928a492ff040f7110c7.min.js"; script.type = "text/javascript"; document.head.appendChild(script); } else { var script = document.createElement("script"); script.src = "https://assets.adobedtm.com/7e08552ade3f/1a8047d2b483/launch-f46125d37e44.min.js"; script.type = "text/javascript"; document.head.appendChild(script); } </script>  <script data-inline-file-name='digitalDataAnalyticsListener.min.js' data-inline-site='tf'>/* Hash: 468bd07150dbbf Source: /tf/js/dist/digitalDataAnalyticsListener.min.js */ !function(){"use strict";window.digitalDataAnalyticsListener={initted:!1,init:function(){this.emailCampaignRecord()},emailCampaignRecordFired:!1,emailCampaignRecord:function(){if(0!=digitalData.merchandisingDataInitted)if(1!=this.emailCampaignRecordFired){var i=digitalData.merchandising,a=i.emid;void 0!==a&&null!=a&&""!=a?(console.log("digitalDataAnalyticsListener: Email campaign tracking recored about to fire"),$.ajax({headers:{"Content-Type":"application/json; charset=utf-8"},url:environmentURL.DATAHUB+"/datahub/api/v1/datalayer/record",dataType:"json",type:"POST",contentType:"application/json",data:JSON.stringify({hit_domain:window.location.hostname,referrer:i.referrer,analyticsVisitorid:i.analyticsVisitorID,marketingCloudid:i.marketingCloudVisitorID,dmOfferSessionid:i.sessionId,s_vi_low:i.s_vi_low,s_vi_high:i.s_vi_high,icid:i.icid,cid:i.cid,emid:i.emid,amoid:i.amoid,formid:digitalData.form,gigya_uid:digitalData.user.gigyaId}),success:function(i){console.log("digitalDataAnalyticsListener: Success",i),digitalDataAnalyticsListener.emailCampaignRecordFired=!0},error:function(i){console.log("digitalDataAnalyticsListener: Data not persisted",i),digitalDataAnalyticsListener.emailCampaignRecordFired=!1}})):console.log("digitalDataAnalyticsListener: Email campaign tracking NOT triggered as emid is not present")}else console.log("digitalDataAnalyticsListener: Email campaign record was successfully fired once before");else console.log("digitalDataAnalyticsListener: Not ready to fire email campaing record")}}}(),window.digitalDataAnalyticsListener.init();</script> <script id="chatLauncher" src="//chat-api.thermofisher.com/search/chat-launcher/chat-launcher.js" defer></script>  <div id="landscape-banner"> <div class="interactoffers"> <div class="dynamic-offer" id="tf-headerfooter-lb" data-placement-type="headerfooter" data-placement-code="lb" data-default-snippet=""> </div> </div> </div> </div> </footer> </div> <form id="productForm" name="productForm" method="POST"></form>  <form action="&CID=&ICID=" method="POST" id="IVGNaddToCartForm"> <input id="IVGNAddToCartXML" name="AddToCartXML" type="hidden" value="" /> </form> <iframe style="display:none;" id="addToFavoritesTarget">AddToFavs result goes here(DO NOT DELETE ME!)</iframe> <div id="pop-add" class="mag-dialog on-top" style="display: none;"> <div class="dialog-content" style="padding-bottom: 20px;"> <button class="close pop-add-cls" type="button">Close X</button> <h3 style="margin-bottom: 0px;"> Your item<span id="pop-plural" style="display: none; float: none;">s have</span><span id="pop-sing" style="float: none;"> has</span> been added! </h3> <br /> <input type="button" class="pop-b button primary-button core-view" value="View Cart" /> <input type="button" class="button commerce-button checkout pop pop-b core-checkout" value="Checkout" /> </div> </div>  <script> var _savedJQuery = window.$; window.jQuery = window.$j; </script> <script> window.$ = _savedJQuery; window.jQuery = _savedJQuery; </script> <script> $m.assayType = ''; </script>  <div style="display:none" id="debugMessage"> Host server : magellan-search-blue-5c9c5c4749-97l6p:80/100.66.76.85:80. <br>git-commit: d22414ba47b22cc02ffc24003f0e179da61511a6 <br>git-url: https://github.com/thermofisher/magellan-search <br>git-branch: release/2.21.0-Offline </div> <script> $m.translations = {"antibody.serp.filter.ptm":"PTM","antibody.serp.footer.talk":"Talk to a specialist now","immunoassay.elisa.zero.results.reason.one":"Spelling or typing errors. You can use the product search to modify your search.","antibody.pdp.documents":"Documents","antibody.pdp.productDetail.conjugate":"Conjugate","common.search.modal.faq.heading.success":"Thank you for your feedback","microbe.zero.results.reason":"Possible reasons that no Assays were found:","global.search.results.faqCard.feedback":"Provide Feedback on this Answer","global.search.secondaryResults.navigators.manualsAndProtocols.nav1":"Document Types","antibody.zero.results.other.subtype.two":"Zero results for \"{0}\" but we found \u003ca href\u003d\"{1}query/{0}\"\u003e{2} {3}\u003c/a\u003e and \u003ca href\u003d\"{4}query/{0}\"\u003e{5} {6}\u003c/a\u003e that match your search.","global.search.results.cmgtProdCard.specifications":"General Specifications","antibody.pdp.reference.zeroResultBtnTxt":"Cite this product","antibody.pdp.productDetail.elisa":"ELISA","common.wsp.tooltip.info":"Web orders only. Excludes Supply Centers.","global.search.filter.persona.allResults":"All Results","common.search.modal.search.heading":"What were you looking for?","antibody.pdp.reference.benchscilink":"View published figure on \u003cimg class\u003d\"benchsci-logo\" src\u003d\"/order/genome-database/assets/img/benchsci-logo.svg\"\u003e\u003cimg src\u003d\"/content/dam/LifeTech/Images/Header/jumpout-link.png\"\u003e","crispr.zero.results.contact":"GEMServices@thermofisher.com","global.search.results.genomicsHelperCard.productType":"Product Type","antibody.pdp.hero.viewOther.proteinFamilyPageExist":"View all {0} {1}s","elisa.sitemap.description":"ELISA (enzyme-linked immunosorbent assay) is a plate-based technique for detection and quantification of antibodies or proteins such as cytokines, chemokines, growth factors, hormones, and intracellular phosphorylated proteins.","global.search.results.probesStructureCard.casNameAndNumber":"CAS Name/Number","global.search.results.geneCard.entrezGeneID":"Entrez Gene ID","antibody.searchresults.rowheader.host":"Host","elisa.crossSellCard.select.antibody.forKit":"Select Antibodies for your kit","global.search.noResults.resources.requestMsds":"Request an MSDS","antibody.pdp.productDetail.cytotoxicityassay":"Cytotoxicity Assay","antibody.pdp.bioinformatics.proteinAliases":"Protein Aliases:","global.search.qty.invalid":"Please enter a quantity in the range of 1 to 9999.","global.search.results.faqCard.answerId":"Answer Id: {0}","serp.nav.tabs.isotype.controls":"Isotype Controls","global.search.results.handbookCard.resultType":"Molecular Probes Handbook","antibody.pdp.reference.less":"less ","elisa.pdp.hero.reference":" Reference","elisa.crossSellCard.find.exact.antibody":"Find the exact antibody for your Elisa kit.","global.search.results.probesStructureCard.resultType":"Chemical Structure","elisa.sitemap.titleprefix":"ELISA Kits","elisa.pdp.productdetails.speciesreported":"Species (reported)","serp.filter.lessText":"Less","elisa.searchresults.rowheader.timetoresult":"Time To Result","antibody.serp.compare.storage.conditions":"Storage Conditions","global.search.results.cmgtProdCard.supportDocuments":"Support Docs","global.search.button.configure":"Configure","serp.filtertext.displayname.species":"Species","global.search.noResults.needHelp.contactUs":"Contact Us","antibody.pdp.productDetail.chipassay":"ChIP assay","global.search.results.mediaFormulationCard.catNo":"Catalog #s","antibody.searchresults.rowheader.product":"Product","antibody.serp.compare.class.type":"Class / Type","antibody.searchresults.sop.save":"Save","global.search.results.probesStructureCard.viewMoreComponents":"View More","antibody.serp.compare.reference":"Reference","oligos.jpOligos.bulkUpload.uploadOptionsHeader":"Select the default options below to apply to your imported sequences.","antibody.tfp.desc.viewmore":"View more","antibody.pdp.productDetail.fluorescenceresonanceenergytransfer":"Fluorescence Resonance Energy Transfer ","info.tout.footer.createTxt":"Create","immunoassay.elisa.zero.results.other":"However, we found \u003ca href\u003d\"{0}\"\u003e{1} other\u003c/a\u003e results on the site","antibody.pdp.productDetail.westernblot":"Western Blot","global.search.noResults.heading":"No Results","global.search.results.vectorCard.resultType":"Vector Map","antibody.pdp.productDetail.readytouseimmunoassay":"Ready-To-Use Immunoassay","elisa.pdp.productdetails.genesymbol":"Gene symbol","global.search.results.geneCard.species":"Species","antibody.pdp.reference.mostrecent":"Most recent ","global.search.noResults.querySuggestionWithResults":"Search for: \"\u003ca href\u003d\"{0}\"\u003e{1}\u003c/a\u003e\" ({2} matches)","oligos.jpOligos.bulkUpload.pasteSequence":"Copy/Paste Upload","info.modal.header.sharedListdescmobile":"Shared lists are a new way to save products. Create \n a list for each of your projects to share with \n collaborators like your lab manager. Then \n select and buy products as a team. ","antibody.searchresults.row.with.numeric.figure":" figure","elisa.pdp.productdetails.productsize":"Product size","global.search.results.cmgtProdCard.price":"List Price","antibody.pdp.productDetail.immunogen":"Immunogen ","global.search.sharedList.addedTo":"Added to","serp.filtertext.displayname.host":"Host","crispr.searchresults.rowheader.species":"Species","antibody.pdp.productDetail.storagebuffer":"Storage buffer","global.search.button.saveToList":"Save to list","oligos.jpOligos.addOligo.delivery":"Delivery *","info.modal.header.sharedListdesc":"Shared lists are a new way to save products. Create a list for each of your projects to share \n with collaborators like your lab manager. Then select and buy products as a team.","global.search.results.citationCard.productUsage":"Product Usage","antigen.onboarding.message":"Adjust the sliders to select your desired sequence range","antibody.pdp.productDetail.Viewimmunogen":"View immunogen","common.search.modal.search.button.submit":"submit","info.modal.header.createsharedListDesc":"Click \"Save to list\" to create your first list, \n give it a name, and add the product. Access \n your shared lists in the Account link on \n Thermofisher.com. ","global.search.results.featuredResultCard.resultType":"Overview","support.search.techSupport.navigation.productFaqs":"Product FAQs","antibody.pdp.bioinformatics.uniProtID":"UniProt ID:","global.search.results.probesStructureCard.molWeight":"Molecular Weight","proteinnpeptide.sitemap.titleprefix":"Proteins \u0026 Peptides","antibody.searchresults.row.bestseller":"Best Seller","proteinnpeptide.sitemap.description":"Wide range of recombinant proteins, native proteins, and synthetic peptides for cell culture, functional studies and other immunoassays. Select a target to view all proteins.","oligos.jpOligos.bulkUpload.processingWait":"We are processing your request. This may take a few moments. Thank you for your patience.","antibody.searchresults.row.mobile.continue":"Continue","antibody.pdp.productDetail.immunohistochemistrypfafixed":"Immunohistochemistry (PFA fixed)","common.search.modal.faq.button.cancel":"cancel","support.search.techSupport.navigation.orderingAndWebFaqs":"Ordering \u0026amp; Web FAQs","common.search.modal.search.validation.required.feedback":"Please provide feedback","antibody.serp.spellcheck.singleSearchTextKeywordSingular":"\u003cspan class\u003d\"regWeight\"\u003eNo result for\u003c/span\u003e \u003cstrong\u003e{1}\u003c/strong\u003e. \u003cspan class\u003d\"regWeight\"\u003eShowing \u003cstrong\u003e{0} results\u003c/strong\u003e for\u003c/span\u003e {2}","antibody.pdp.footer.helpText":"Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.","antibody.pdp.productDetail.flowcytometry":"Flow Cytometry","global.search.results.genericContentCard.heading":"Buying Guide","serp.flt.srch.placeholder.brand":"Search Brand","serp.flt.srch.placeholder.conjugate":"Search Conjugate","antibody.tfp.subheader.targetinformation":"Target Information","support.search.techSupport.navigation.technicalReferenceLibrary":"Technical Reference Library","global.search.results.cmgtProdCard.numCitations":"View \u003cb\u003e{0}\u003c/b\u003e Citations ","antibody.pdp.productDetail.clone":"Clone","antibody.pdp.productDetail.form":"Form","global.search.noResults.additionalResource.content":"Looking for a \u003ca href\u003d\"/site/us/en/home/support/Certificate-of-Analysis-Request-Form.html\"\u003eCertificate of Analysis\u003c/a\u003e or a \u003ca href\u003d\"/site/us/en/home/support/MSDS-Request-Form.html\"\u003eMSDS\u003c/a\u003e?","global.search.results.msdsCard.resultType":"MSDS","oligos.jpOligos.messages.noProjects":"Please add one or more projects","antibody.pdp.commerceCard.dateTooltipMessage":"Items usually ship within 1 business day from the estimated availability date.","serp.filtertext.displayname.crossadsorbed":"Cross Adsorbed","antibody.pdp.productDetail.antibodiesbyimmunogen":"antibodies by immunogen","antibody.pdp.productDetail.affinitypurification":"Affinity Purification","antibody.pdp.productDetail.immunostaining":"Immunostaining","antibody.searchresults.row.mostfigures":"Most Figures","antibody.pdp.productDetail.inhibitionassays":"Inhibition Assays","antibody.searchresults.row.account.price.tooltip":"Your account price is the best price.","global.search.noResults.searchTips.heading":"Search Tips:","antibody.searchresults.row.mobile.select":"Select","unified.card.mirna":"miRNA mimics and inhibitors","oligos.jpOligos.addOligo.modificationsAndOptions":"Modifications and options","antibody.searchresults.row.mobile.done":"Done","global.button.sharedList.createTxt":"Create","antibody.pdp.hero.proteins.viewOther":"View all ({0}) {1} proteins","antibody.searchresults.tabheader.products":"Products","antibody.pdp.productDetail.expressionSystem":"Expression System","elisa.pdp.productdesc.have.you.cited.this.product":"Have you cited this product in a publication? ","antigen.searchresults.nosearchresults":"No search results","global.search.results.minipdp.manuls.heading":"Manuals \u0026 Product Inserts ","support.search.searchTips":"Search Tips","antibody.pdp.productDetail.activity":"Activity","serp.tabheader.searchby":"Search by","antibody.pdp.productDetail.blockingassay":"Blocking Assay","crispr.zero.results.contact.assistance":"for assistance.","antibody.pdp.productDetail.dotblot":"Dot blot","antibody.pdp.reference.citation":"citation","global.search.results.vectorCard.map":"Map","support.search.noResults.heading":"No Results","antibody.pdp.hero.dataSheets":"Datasheet","antibody.pdp.commerceCard.checkYourPrice":"Check your price","antibody.searchresults.row.guest.user.tooltip":"now to see your best price.","global.search.results.probesStructureCard.molFormula":"Molecular Formula","microbe.zero.results":"No results found","antigen.searchresults.rowheader.sequenceRange":"Sequence Range","antibody.pdp.productDetail.endotoxinconcentration":"Endotoxin concentration","serp.filtertext.displayname.new":"New","serp.filtertext.displayname.format":"Format","oligos.jpOligos.addOligo.baseCount":"Base Count","antibody.pdp.productDetail.species":"Species","antibody.searchresults.row.online.offer":"Online offer: ","oligos.jpOligos.addOligo.reverseComplementOligoName":"Reverse Complement Oligo Name *","antibody.pdp.productDetail.radioimmuneassays":"Radioimmune Assays","serp.panel.builder.adText.tryPB":"Try Panel Builder","global.search.results.itemsPerPage":"Results per page","antibody.pdp.imageGallery.dataGallery":"Data Gallery","antibody.pdp.reference.year":"Year","antibody.pdp.hero.viewOther":"View all ({0}) {1} antibodies","antibody.pdp.bioinformatics.entrezGeneID":"Entrez Gene ID:","antibody.pdp.productDetail.testedApplication":"Applications","global.search.results.assayCard.assayId":"Assay ID","antibody.searchresults.row.mobile.filter.results":"Filter results","antibody.pdp.productDetail.chipsequencing":"ChIP-sequencing","support.search.techSupport.navigation.allSupportDocs":"MSDS, COA \u0026amp; other Support Documents","antibody.serp.compare.references":"s","antibody.serp.filter.protein.name":"Protein Name","antibody.pdp.commerceCard.pdlt.2-4weeks":"2-4 Weeks","zrp.no.results":"No results for \"{0}\" in {1}","global.search.noResults.needHelp.detailedSearchTips":"Detailed Search Tips","antigen.searchresults.rangeText":"Select your sequence range","serp.flt.srch.placeholder.proteintarget":"Search Protein Target","serp.filtertext.displayname.proteintarget":"Protein Target","antigen.searchresults.resetsearchbtn":"Reset search","antibody.searchresults.rowheader.offer.ends":"Offer ends ","antibody.pdp.bioinformatics.processes":"Process(es)","antibody.pdp.footer.helpTitle":"We\u0027\u0027\u0027re here to help","antibody.pdp.productDetail.neutralization":"Neutralization","antibody.pdp.productDetail.tcellactivation":"T-Cell Activation","global.search.results.cmgtProdCard.productApplications.label":"Product Applications","antibody.serp.compare.antibody.form":"Antibody Form","antibody.pdp.productDetail.immunofluorescence":"Immunofluorescence ","global.search.results.dayCard.heading":"Learn more about","antibody.comparepage.compare":"Compare","global.search.results.msdsCard.msdsFiles":"MSDS Files","global.search.results.assayCard.productType":"Product Type","support.search.navigator.documentType.label.lull":"Limited Use Label Licenses","support.search.placeholder.tip.msds":"by catalog number or product name","antibody.serp.compare.concentration":"Concentration","unified.card.proteins":"Recombinant proteins and peptides","support.search.techSupport.navigation.contactOrderSupport":"Contact Order Support","crispr.zero.results.reason.two":"The products are listed under an alternate gene name. Try using Entrez Gene ID or a synonym as an identifier.","antibody.pdp.bioinformatics.header":"Bioinformatics","antibody.searchresults.row.advanced.verification":"Advanced Verification","antibody.pdp.productDetail.purification":"Purification","support.search.placeholder.tip.citationsAndReferences":"by catalog number or keyword","antibody.pdp.productDetail.immunoradiometricassay":"Immunoradiometric Assay","antibody.searchresults.rowheader.price.symbol":"CNY","elisa.pdp.productdetails.analyticalsensitivity":"Analytical sensitivity","support.search.navigator.documentType.label.all":"All Support Documents","antibody.pdp.productDetail.immunodiffusion":"Immunodiffusion","antibody.searchresults.row.load.more.results":"Load {0} more results","support.search.results.found":"[{0} matches]","antibody.searchresults.row.special.offer":"Special offer: ","antibody.serp.compare.target":"Target","support.search.placeholder.tip.mediaFormulations":"by catalog number","global.search.pagination.nextPage":"Next \u0026gt;","elisa.pdp.showLess.button":"Show Less","common.search.modal.faq.label.expectations.exceeded":"Exceeded","elisa.serp.createOwn.section":"Create Your Own ELISA","global.search.results.lullCard.lullFiles":"Limited Use Label Licenses","serp.loadmore.viewText":"Viewing {0} {1} {2}","oligos.jpOligos.addOligo.scale":"Synthesis Scale *","global.search.form.searchWithin.message":"Search Within","antibody.pdp.commerceCard.offerends":"Offer ends","global.search.error.heading":"An error occurred during search.","antibody.serp.filter.showLess.filters":"Show Less","antibody.pdp.reference.citations":"citations","common.search.modal.faq.validation.invalid.email":"Please enter a valid email address","antibody.serp.compare.cross.adsorption":"Cross Adsorption ","antibody.serp.compare.immunogen":"Immunogen","oligos.jpOligos.bulkUpload.templateDownloadButton":"Download Sequence Template","antibody.sitemap.primary.titleprefix":"Primary Antibodies","antibody.searchresults.row.best.price.tooltip":"This is your best price.","common.search.modal.faq.label.body":"Feedback on FAQ:","global.search.noResults.additionalResource.heading":"Additional Resources:","global.search.results.geneCard.resultType":"Gene","support.search.navigator.documentType.label.brochures":"Product Literature","antibody.pdp.reference.see":"See","microbe.zero.results.contact.three":"for direct assistance. In most cases, our service desk will respond within 1 business day.","global.search.sortingOptions.dateSort.descending":"Newest First","antibody.pdp.productDetail.contains":"Contains","global.search.enterListName.watermark":"Enter list name","oligos.jpOligos.messages.emptyProject":"One or more projects do not contain any oligos","antibody.searchresults.row.cat":"Cat #","support.search.navigator.documentType.label.coa":"Certificates of Analysis","elisa.pdp.productdetails.labelordye":"Label or dye","oligos.jpOligos.common.buttons.newProject":"New Project","antibody.searchresults.row.special.price.tooltip":"Special offer is your best price.","serp.filtertext.displayname.conjugate":"Conjugate","antibody.serp.filter.brand":"Brand","global.search.results.manualCard.catNo":"Cat. No.","antibody.pdp.productDetail.aminoacidsequence":"Amino acid sequence","antibody.searchresults.row.online.price":"Online price: ","serp.flt.srch.placeholder.cellline":"Search Cell Line","serp.nav.tabs.proteins.peptides":"Proteins and Peptides","antibody.comparepage.print":"Print","global.search.results.posterCard.resultType":"Scientific Poster","antibody.pdp.productDetail.purity":"Purity","antibody.pdp.commerceCard.contactus":"Contact Us","antibody.pdp.productDetail.relativeexpression":"Relative expression","elisa.pdp.productdetails.timetoresult":"Time-to-result","global.search.results.manualCard.resultType":"Manual / Product Insert","global.search.results.protocolCard.resultType":"Experiment Protocol","antibody.zero.results.other":"Zero results for \"{0}\" but we found \u003ca href\u003d\"{1}\"\u003e{2} other results\u003c/a\u003e on the site.","global.search.noResults.resources.requestCoa":"Request a Certificate of Analysis","global.search.results.citationCard.id":"ID","antibody.pdp.commerceCard.pdlt.1-2weeks":"1-2 Weeks","support.search.form.searcharea.refine.label":"Refine your search","global.search.error.body":"Please review your keyword and try again.","antibody.pdp.productDetail.immunomicroscopy":"Immunomicroscopy","support.search.placeholder.tip.vectors":"by catalog number or product name","crispr.zero.results.reason":"Possible reasons that no CRISPR Guide RNA were found:","unified.card.isotype":"Isotype controls","serp.flt.srch.placeholder.clone":"Search Clone","antibody.serp.filter.antibody.form":"Antibody Form","global.search.button.quickProductInfo":"Quick Product Info","common.search.modal.faq.validation.required.feedback":"Please provide feedback","antibody.pdp.commerceCard.quantity":"Quantity","antibody.pdp.productDetail.storageconditions":"Storage conditions","antibody.serp.compare.clone":"Clone","crispr.searchresults.rowheader.assayId":"Assay ID","global.search.results.manualCard.download":"Download","oligos.jpOligos.bulkUpload.fileUpload":"DNA File Upload","elisa.pdp.productdetails.proteinfamily":"Protein family","antibody.pdp.hero.references":"{0} Reference{1}","antibody.pdp.productDetail.peptidearray":"Peptide Array","antibody.pdp.imageGallery.benchsciImageText":"View full figure on","common.search.modal.faq.label.expectations.notMet":"Not Met","global.search.results.genomicsHelperCard.resultType.mirna":"miRNA Mimic, Inhibitor and Assay","antibody.serp.compare.conjugate":"Conjugate","global.search.noResults.resources.heading":"Resources","oligos.jpOligos.addProject.addOligo":"Add Oligo","antibody.pdp.productDetail.crossadsorption":"Cross Adsorption","unified.card.antibody":"Antibodies","antibody.serp.singleSearchText":"{0} results","unified.card.taqman":"TaqMan™ assays and arrays","info.modal.header.learnMoresharedList":"Learn More","global.search.results.dayCard.resultType":"Overview","oligos.jpOligos.basicEntry.help":"Help","antibody.pdp.footer.helpButton":"Contact tech support","global.search.results.brochureCard.version":"Version","elisa.searchresults.rowheader.sensitivity":"Sensitivity","antibody.pdp.commerceCard.pendingTooltipChinaSCMessage":"We can\u0027t get availability information for you right now. Items usually ship with the next Supply Center shipment.","crispr.searchresults.rowheader.price":"Price (USD)","oligos.jpOligos.bulkUpload.invalidFileFormat":"Invalid file type - please save file as .xls, .csv or .txt and upload again.","elisa.pdp.productdetails.assaykitformat":"Assay kit format","support.search.placeholder.tip.spectra":"by catalog number","global.search.results.genericContentCard.resultType":"Buying Guide","serp.filtertext.displayname.producttype":"Product Type","antibody.pdp.productDetail.antibodyform":"Antibody Form","antibody.pdp.commerceCard.availability.text":"Estimated availability date: ","global.search.results.faqCard.answer":"Answer","antibody.pdp.productDetail.immunoprecipitation":"Immunoprecipitation","antibody.comparepage.addtocart":"Add to cart","antibody.pdp.productDetail.Viewall":"View all","antibody.serp.comapre.not.in.region":"Product not available in your region","antibody.pdp.reference.authors":"Authors","antibody.pdp.productDetail.targetInformation":"Target Information","oligos.jpOligos.common.buttons.import":"Import","common.search.modal.search.validation.invalid.email":"Please enter a valid email address","microbe.zero.results.contact.one":"Please contact","antibody.serp.filter.protein.target":"Protein Target","microbe.zero.results.reason.two":"The assay is listed under an alternate gene/protein name. Try searching for synonyms.","unified.card.secondary":"Secondary antibodies","global.search.results.featuredResultCard.heading":"Featured Product","antibody.pdp.hero.publishedFigures":"{0} Published Figure{1}","antibody.pdp.productDetail.forresearchuseonlynotforuseindiagnosticproceduresnotforresalewithoutexpressauthorization":"For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.","info.modal.header.collaboratesharedListHeader":"Collaborate","antibody.searchresults.row.reference":" Reference","global.search.results.cmgtProdCard.contactUs.Url":"http://template.day.fqdn/site/us/en/home/Global/Contact-Us.html","global.search.noResults.searchTips.list":"\u003cli\u003eRe-check spelling of search word(s).\u003c/li\u003e\u003cli\u003eSearch with fewer words. For example, instead of searching for \"Countess Automated Cell Counter\", try searching for \"Countess\".\u003c/li\u003e\u003cli\u003eRemove any special characters from catalog numbers. For example, instead of searching for \"XYZ-123\", try searching for \"XYZ123\".\u003c/li\u003e","oligos.jpOligos.addProject.researcherName":"Researcher Name *","antibody.pdp.commerceCard.performanceGuarantee":"Performance Guarantee","oligos.jpOligos.basicEntry.mainHeading":"Custom DNA Oligos","antibody.searchresults.rowheader.clearall":"Clear all","antibody.pdp.imageGallery.validationinfo":"validation info.","global.search.sortingOptions.dateSort.ascending":"Oldest First","antibody.serp.filter.product.type":"Product Type","microbe.zero.results.reason.three":"Spelling or typing errors. You can use the search above to modify your search,","global.search.results.cmgtProdCard.ratings.heading":"User Ratings","global.search.results.cmgtProdCard.seeAll":"See all","antibody.pdp.productDetail.immunohistochemistryfrozen":"Immunohistochemistry (Frozen)","elisa.pdp.productdetails.genealiases":"Gene aliases","antibody.searchresults.sop.price":"Price","crispr.searchresults.rowheader.gene":"Gene","antibody.searchresults.row.sop.online.price":"Online exclusive","antibody.pdp.reference.species":"Species","elisa.pdp.hero.about.this.kit.rigorousvalidation":"Rigorous validation","antibody.pdp.productDetail.publishedSpecies":"Published species","antibody.searchresults.row.with.numeric.figures":" figures","elisa.crossSellCard.customAssay.service":"Custom Assay Services","antibody.serp.footer.desc1":"Searching for an antibody we don\u0027\u0027t offer? We make custom antibodies for specific targets, species and applications.","antibody.serp.footer.desc2":"More than 18,000 custom antibodies created so far.","global.search.results.lullCard.resultType":"Limited Use Label License","oligos.jpOligos.deleteOligo.title":"Confirmation","antibody.pdp.productDetail.rrid":"RRID","antibody.pdp.productDetail.competitionassay":"Competition Assay","antibody.pdp.productDetail.agglutination":"Agglutination","common.search.modal.faq.label.expectations":"Expectations:","serp.filtertext.displayname.tag":"Tag","global.search.noResults.resources.realTimePCRCatalog":"Looking for TaqMan\u0026reg; Assay or Silencer\u0026reg; siRNA products? View our \u003ca href\u003d\"http://template.day.fqdn/site/us/en/home/Products-and-Services/Applications/Nucleic-Acid-Amplification-and-Expression-Profiling/Real-Time-PCR.html\"\u003eReal-Time PCR catalog\u003c/a\u003e.","elisa.pdp.productdetails.homogenousnowash":"Homogenous (no wash)","oligos.jpOligos.bulkUpload.field.scale":"Synthesis Scale *","antibody.serp.filter.laser.compatibility":"Laser Compatibility","antibody.searchresults.rowheader.expressionSystem":"Expression System","antibody.pdp.productDetail.hemagglutinationassay":"Hemagglutination Assay","antibody.pdp.productDetail.immunohistochemistryparaffin":"Immunohistochemistry (Paraffin) ","antibody.searchresults.rowheader.compare":"Compare","serp.filtertext.displayname.expressionsystem":"Expression System","global.search.results.mediaFormulationCard.resultType":"Media Formulation","elisa.crossSellCard.shopFor.antibody":"Shop for Antibodies","global.search.results.genomicsHelperCard.find":"Find {0} that match your search term \"\u003ca href\u003d\"{1}\"\u003e\u003cstrong\u003e{2}\u003c/strong\u003e\u003c/a\u003e\"","antibody.serp.filter.application":"Application","antibody.serp.compare.published.application":"Published Application","support.search.navigator.documentType.label.citations":"Citations \u0026amp; References","oligos.jpOligos.common.buttons.cancel":"Cancel","antibody.zero.results.reason.one":"Spelling or typing errors. You can use the product search to modify your search.","antibody.pdp.imageGallery.figure":"FIGURE","antibody.pdp.commerceCard.pendingTooltipMessage":"We can\u0027t get availability information for you right now. Items usually ship within 1 business day of when they become available.","antibody.pdp.productDetail.proteineassaysandanalysis":"Proteine Assays and Analysis","elisa.pdp.hero.techsupport":"Tech Support","antibody.pdp.reference.dilution":"Dilution ","global.search.results.cmgtProdCard.description":"Description","oligos.jpOligos.addOligo.minMaxOligoSequence":"Please enter a minimum of 7 and maximum of 30. Please make sure that there are no spaces before, after, or inside the sequence. U/I/F/E/O/Z are not allowed.","antibody.pdp.productDetail.lateralflow":"Lateral Flow","global.search.pagination.previousPage":"\u0026lt; Prev","antibody.pdp.productDetail.target":"Target","elisa.pdp.productdetails.detectorantibodyconjugate":"Detector antibody conjugate","antibody.zero.results.browse.all":"Browse all ","antibody.searchresults.rowheader.results":" results","antibody.pdp.commerceCard.requestBulkOrCustomFormat":"Request bulk or custom format","antibody.pdp.productDetail.tag":"Tag","antibody.zero.results.other.one":"Zero results for \"{0}\" but we found \u003ca href\u003d\"{1}\"\u003e{2} other result\u003c/a\u003e on the site.","antibody.pdp.imageGallery.benchsci.disclaimer2":"Disclaimer","antibody.pdp.imageGallery.benchsci.disclaimer1":"By clicking this image or link above, you will be redirected to the Benchsci website. ","support.search.techSupport.navigation.contactProductSupport":"Contact Product Support","elisa.pdp.productdetails.unitproid":"UniProt ID","antibody.pdp.productDetail.orthoganalmethod":"Orthoganal method","antibody.pdp.commerceCard.catalog":"Catalog # ","global.search.noResults.youSearchedFor":"\u003cstrong\u003eSearch for:\u003c/strong\u003e \u003ch1\u003e${query}\u003c/h1\u003e \u003cem\u003e(0 matches)\u003c/em\u003e","antibody.serp.filter.clear.filters":"Clear","antibody.serp.compare.host.isotype":"Host/Isotype","antibody.pdp.productDetail.viewmore":"View more","support.search.techSupport.navigation.training":"Training","serp.filtertext.displayname.productgrade":"Product Grade","global.search.results.cmgtProdCard.resultType":"Catalog Product","common.search.modal.search.label.body":"*Please provide feedback to help improve our search:","support.search.placeholder.tip.structures":"by catalog number or product name","global.search.results.found":"You searched for: ","antibody.pdp.productDetail.independentantibody":"Independent antibody","antibody.pdp.imageGallery.benchsci.disclaimerMessage":"Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.","global.search.results.faqCard.askNewQuestion":"Ask a New Question","antibody.pdp.productDetail.hostIsotype":"Host/Isotype","antibody.pdp.imageGallery.advancedVerification":"Advanced Verification","global.search.results.geneCard.aliases":"Aliases","antibody.serp.compare.tested.applications.dilution":"Tested Applications / Dilution","antibody.serp.compare.contains":"Contains","immunoassay.elisa.zero.results.reason.two":"The protein target is listed under an alternate gene/protein name. Try searching for synonyms.","secondary.sitemap.description":"Secondary antibodies for fluorescent, colorimetric, and chemiluminescent detection. Wide selection of antibodies for Western blot, IHC, ICC/IF, Flow Cytometry \u0026 ELISA. Select a target species to view all formats.","global.search.results.cmgtProdCard.catNo":"Catalog #","oligos.jpOligos.addOligo.oligoNameMessage":"You may enter up to 30 single-byte alphanumeric characters, including (,), -, _, and spaces.","global.search.button.supportDocuments":"Support Documents","global.search.filter.productAttributeFilters":"PRODUCT FILTERS","antibody.searchresults.rowheader.remove":"Remove","antibody.pdp.relatedAntibodiesHeader":"Related Antibodies","oligos.jpOligos.bulkUpload.uploadOptionsDescription":"Selected options will be applied to all \u003cu\u003eblank\u003c/u\u003e entries of the spreadsheet and will not overwrite any existing spreadsheet selections.","serp.filtertext.displayname.antibodyform":"Antibody Form","global.search.secondaryResults.navigators.faq.nav1":"Applications","global.search.secondaryResults.navigators.faq.nav3":"Brands","antibody.searchresults.tabheader.antigens":"Epitopes","antibody.searchresults.row.figure":"figure","global.search.secondaryResults.navigators.faq.nav2":"Product Categories","antibody.pdp.hero.textProtocols":"Protocols","antibody.pdp.productDetail.viewless":"View less","antibody.serp.filter.protein.length":"Protein Length","info.tout.footer.exportTxt":"Export","antigen.searchresults.nosearchresultsmsg":"There are no antigen sequence ranges that match your search. Try resizing the end points in your range.","elisa.pdp.showMore.button":"Show More","elisa.crossSellCard.requestQuote":"Request a quote","serp.filtertext.displayname.researcharea":"Research Area","antibody.pdp.productDetail.viewadditionalformats":"View additional formats","antibody.serp.filter.host":"Host","antibody.pdp.commerceCard.checkYourPriceAndAvailability":"Check your price \u0026 availability","antibody.pdp.reference.journal":"Journal ","global.search.results.cmgtProdCard.contactUs":"Contact Us","info.modal.header.collaboratesharedListDesc":"You can invite collaborators like your lab \n manager or procurement staff to any shared \n list. They can add more items, leave \n comments and complete the final purchase. ","antibody.zero.results":"Zero Results.","antibody.pdp.panelBuilder.videoHeading":"How to use the Panel Builder","serp.filtertext.displayname.recombinant":"Recombinant","antibody.pdp.documents.msds":"Material safety data sheets (MSDS)","unified.card.gene":"Branched DNA gene expression assays","elisa.pdp.productdetails.proteinaliases":"Protein aliases","antibody.pdp.productDetail.knockdown":"KnockDown","antibody.pdp.imageGallery.testingData":"Testing Data","serp.filtertext.displayname.adv.verification":"Adv. Verification","crispr.zero.results.reason.four":"The product has been discontinued.","oligos.jpOligos.addOligo.complementOligo":"Complement Oligo","secondary.sitemap.titleprefix":"Secondary Antibodies","antibody.pdp.footer.performanceGuaranteeButton":"Learn more","info.modal.header.exportsharedListDesc":"Export your list as a spreadsheet for \n easy documentation or hand off to your lab’s \n designated buyer. ","antibody.pdp.imageGallery.relativeexpression":"Relative expression","antibody.searchresults.rowheader.application":"Application","serp.filtertext.displayname.clonality":"Clonality","antibody.pdp.commerceCard.productnotavailableinyourregion":"Product not available in your region","common.search.modal.search.button.cancel":"cancel","info.tout.footer.collaborateTxt":"Collaborate","unified.card.sirna":"siRNA","common.search.modal.faq.label.email":"Email Address:","global.search.results.brochureCard.download":"Download","antibody.serp.compare.tested.species.reactivity":"Tested Species Reactivity","global.search.results.citationCard.resultType":"Citations \u0026amp; References","antibody.pdp.productDetail.insituhybridization":"In Situ Hybridization","oligos.jpOligos.bulkUpload.templateDownloadHeader":"Click below to download the Excel template to your local computer","global.search.results.assayCard.resultType":"Assay","antibody.pdp.hero.techSupport":"Tech Support","antibody.serp.filter.target.class":"Target Class","support.search.techSupport.navigation.events":"Events","unified.card.crispr":"CRISPR guide RNA","flow.cytometry.search.text":"Target, gene symbol","support.search.noResults.noResultsFoundForQuery":"We did not find results for: \u003cstrong\u003e${query}\u003c/strong\u003e in \u003cstrong\u003e${supportSearchArea}\u003c/strong\u003e.","antibody.serp.filter.clone":"Clone","antibody.searchresults.row.price.not.available":"Price not available","antibody.serp.singleSearchTextKeywordSingular":"{0} result","common.search.modal.faq.validation.required.email":"Please provide an email address","global.search.button.addToCart":"Add To Cart","global.search.results.cmgtProdCard.miniPdp.heading":"Product Detail","elisa.serp.notFinding.section":"Not finding what you\u0027re looking for?","elisa.pdp.productdetails.intraassaycv":"Intraassay CV","antibody.pdp.productDetail.rnaimmunoprecipitation":"RNA Immunoprecipitation","antibody.serp.compare.description":"For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.","oligos.jpOligos.bulkUpload.pasteSequenceDescription2":"","oligos.jpOligos.bulkUpload.pasteSequenceDescription1":"Please enter sequence individually, one record per line, separated by commas, with no space after the comma.","antibody.pdp.productDetail.miscellaneous":"Miscellaneous","antibody.serp.compare.storage.buffer":"Storage Buffer","elisa.pdp.hero.technicalguideprotocol":"Technical guide \u0026 protocol","antibody.pdp.productDetail.productSpecificationHeader":"Product Specific Information","antibody.pdp.productDetail.productspecifications":"Product Specifications","elisa.pdp.bioinformatics.proteinAliases":"Protein Aliases","serp.filtertext.displayname.application":"Application","global.search.listName.invalid":"Please enter a different list name that does not include the following: ?,/,\\,%,^,!","support.search.techSupport.navigation.instrumentRepair":"Instrument Repair","elisa.pdp.productdetails.proteinsubtype":"Protein subtype","oligos.jpOligos.common.buttons.addToCart":"Add To Cart","oligos.jpOligos.addProject.project":"Project","immunoassay.elisa.zero.results":"Zero Results.","common.search.results.catalogNumbers.label":"Catalog #s","serp.filtertext.displayname.uniprotid":"Uniprot ID","support.search.navigator.documentType.label.manualsAndProtocols":"Manuals \u0026amp; Protocols","serp.filtertext.displayname.proteinlength":"Protein Length","global.search.results.orderingWebFaq.heading":"Ordering \u0026amp; Web FAQ","antibody.pdp.hero.viewDetails":"View Details","serp.filter.moreText":"More","antibody.comparepage.disclaimer":"For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.","support.search.techSupport.navigation.manualsAndProtocols":"Manuals \u0026amp; Protocols","antibody.pdp.productDetail.control":"Control","antibody.serp.compare.expression.system":"Expression System","antibody.pdp.productDetail.concentration":"Concentration","microbe.zero.results.reason.four":"The Assay ID you entered does not match the species you selected. Note that you do not need to select a species to search by Assay ID.","serp.filtertext.displayname.proteinname":"Protein Name","antibody.pdp.productDetail.speciesReactivity":"Species Reactivity","antibody.pdp.suggestedSecondaryAntibodyHeader":"Suggested Secondary Antibodies","antibody.searchresults.tabheader.images":"Images","antibody.pdp.productDetail.molecularweight":"Molecular weight","control.sitemap.titleprefix":"Isotype Controls","oligos.jpOligos.addOligo.optional":"(optional)","antibody.searchresults.row.mostfigures.references":"Most Figures and References","global.search.results.coaCard.catNo":"Catalog #","antibody.pdp.commerceCard.pricenotavailable":"Price not available","antibody.searchresults.rowheader.figures":"Figures","oligos.jpOligos.common.buttons.bulkUpload":"Bulk Upload","elisa.pdp.productdetails.sampletypevolume":"Sample type/volume","antibody.pdp.productDetail.class":"Class","support.search.placeholder.tip.orderingWebFaq":"by keyword","antibody.pdp.productDetail.westernblotagglutination":"Western Blot (Agglutination)","antibody.comparepage.share":"Share","antibody.pdp.imageGallery.published.figure.supplied.by":"Published figure supplied by","antibody.serp.singleSearchTextKeywordPlural":"{0} results","antibody.pdp.imageGallery.antibodyTestingData":"Antibody Testing Data","support.search.placeholder.tip.coa":"by lot number or catalog number","antibody.pdp.commerceCard.availability.pending":"Pending","antibody.serp.filter.less.filters":"Less","antibody.pdp.productDetail.monoclonal":"Monoclonal","global.search.noResults.needHelp.heading":"Need Help?","antibody.serp.spellcheck.singleSearchTextKeywordPlural":"\u003cspan class\u003d\"regWeight\"\u003eNo results for\u003c/span\u003e \u003cstrong\u003e{1}\u003c/strong\u003e. \u003cspan class\u003d\"regWeight\"\u003eShowing \u003cstrong\u003e{0} results\u003c/strong\u003e for\u003c/span\u003e {2}","elisa.pdp.hero.target.information":"Target information","antibody.searchresults.row.figures":"figures","antibody.pdp.panelBuilder.videoDescription":"Watch the video to learn how to use the Invitrogen Flow Cytometry Panel Builder to build your next flow cytometry panel in 5 easy steps.","bid.common.tooltip.new.price.info":"\u003cstrong\u003ePrice:\u003c/strong\u003e Manufacturer suggested price \u003cbr\u003e \u003cstrong\u003eOnline price:\u003c/strong\u003e Web channel price","support.search.placeholder.tip.default":"by catalog number or product name","antibody.searchresults.rowheader.details":"Details","global.search.noResults.needHelp.technicalResources":"Technical Resources","antibody.pdp.productDetail.shippingcondition":"Shipping conditions","global.search.filter.persona.hitCount":"[{0}]","elisa.pdp.productdetails.speciestested":"Species (tested)","crispr.zero.results.reason.three":"The Assay ID you entered does not match the species you selected. Note that you do not need to select a species to search by Assay ID.","common.search.modal.search.heading.success":"Thank you for your feedback","global.search.filter.appliedFilters":"CURRENT FILTERS","antibody.pdp.reference.benchsci.disclaimer1":"By clicking the link above, you will be redirected to the Benchsci website. ","zrp.similar.results":"Search similar results in {0}","antibody.pdp.reference.benchsci.disclaimer2":"Disclaimer","antibody.serp.local.contactus":"Contact Us","antibody.searchresults.row.mostreferences":"Most References","support.search.placeholder.tip.productLiterature":"by catalog number or product name","supply.center.tooltip.info":"Products will be shipped from the nearest supply center.","antibody.searchresults.row.references":" References","serp.filtertext.displayname.clone":"Clone","antibody.searchresults.row.publishedfigures":" Published Figures","global.search.results.vectorCard.restrictions":"Restriction","global.search.results.msdsCard.catNo":"Catalog #","crispr.searchresults.rowheader.product":"Product","antibody.searchresults.rowheader.result":" result","global.search.noResults.querySuggestionWithNoResults":"Search for: \"\u003cstrike\u003e{0}\u003c/strike\u003e\" ({1} matches)","serp.filtertext.displayname.antigenspecies":"Antigen Species","antibody.pdp.reference.title":"Title ","global.search.results.geneCard.products":"Gene Based Products","oligos.jpOligos.bulkUpload.fileUploadDescription":"To upload multiple custom DNA oligo sequences, download the Sequence Template, enter the sequence information, and save as an .xls, .csv, or .txt file.","serp.nav.tabs.primary.antibodies":"Primary Antibodies","antibody.searchresults.row.without.keyword":"{0} {3}","antibody.serp.local.tfs":"This product is only available through your local Thermo Scientific supplier","oligos.jpOligos.bulkUpload.example":"Example","support.search.placeholder.tip.lull":"by catalog number or product name ","support.search.navigator.documentType.label.msds":"Material Safety Data Sheets","antibody.zero.results.reason":"Possible reasons that no {0} were found:","antibody.searchresults.row.not.orderable.online":"Not Orderable Online","antibody.serp.compare.add.to.cart":"Add to Cart","global.search.results.genomicsHelperCard.resultType.sirna":"siRNA","oligos.jpOligos.addProject.researcherNameMessage":"Only single-byte alphanumeric characters can be entered.","antibody.searchresults.row.with.keyword.results.header":"\u003cstrong\u003e{0} {3}\u003c/strong\u003e","antibody.searchresults.rowheader.target":"Target","antibody.pdp.productDetail.immunoelectrophoresis":"Immunoelectrophoresis","global.search.results.spectraCard.resultType":"Spectra Data","antibody.tfp.subheader.proteininformation":"Protein Information","global.search.results.brochureCard.documentType":"Product Literature","antibody.pdp.reference.subheading1":"Have you cited this product in a publication? ","antibody.pdp.commerceCard.yourprice":"Your Price","antibody.pdp.reference.subheading2":"Let us know","antibody.pdp.reference.subheading3":"so we can reference it in this datasheet.","crispr.zero.results.reason.one":"Spelling or typing errors. Use the product search above to modify your search.","global.search.results.minipdp.error.message":"This product cannot be ordered online or may be discontinued. For product status please contact \u003ca href\u003d\"http://template.lt.day.fqdn/content/lifetech/global/en/home/technical-resources/contact-us.html\"\u003eOrder Support\u003c/a\u003e.","antibody.pdp.commerceCard.onlineoffer":"Online Offer","antibody.searchresults.row.online.price.tooltip":"Online price is your best price.","support.search.noResults.executeQueryInSiteSearch":"Try this search against our \u003ca href\u003d\"{0}\"\u003eentire website results\u003c/a\u003e.","elisa.pdp.productdetails.geneid":"Gene ID","oligos.jpOligos.addOligo.reverseOligoName":"Reverse Oligo Name *","global.search.results.genomicsHelperCard.resultType.assay":"Assay","oligos.jpOligos.bulkUpload.uploadSelectFileDetails":"(.xls, .csv, or .txt format only; .csv or .txt only if using a procurement system)","oligos.jpOligos.addOligo.reverseComplementOligo":"Reverse Complement Oligo","antibody.serp.filter.target.species":"Target Species","antibody.pdp.reference.sortby":"Sort by","antibody.pdp.productDetail.invitroassay":"In vitro Assay","supply.center.button.text":"Supply Center","immunoassay.elisa.zero.results.reason":"Possible reasons that no {0} kits were found","global.search.results.cmgtProdCard.readMore":"View full product details \u0026gt;","antibody.sitemap.primary.description":"Extensively-validated primary antibodies for Western blot, IHC, ICC/IF, Flow Cytometry, Immunopreciption, ChIP, Functional assays, and other applications. Select a target to view all monoclonal and polyclonal antibodies.","serp.filtertext.displayname.lasercompatibility":"Laser Compatibility","global.search.results.manualCard.version":"Version","pdp.reference.text":"{0} Reference{1}","antibody.pdp.productDetail.gelshift":"Gel Shift","serp.filtertext.displayname.cellline":"Cell Line","antibody.pdp.productDetail.miscellaneouspubmed":"Miscellaneous PubMed ","oligos.jpOligos.messages.invalidOligos":"Please verify oligo parameters below","global.search.results.faqCard.resultType":"Product FAQ","serp.filtertext.displayname.targetclass":"Target Class","antibody.pdp.imageGallery.publishedFigures":"Published Figures","antibody.pdp.commerceCard.instock":"In stock","global.search.results.matches":"[{0} matches]","elisa.pdp.hero.about.this.kit.principleofmethod":"Principle of the method","support.search.placeholder.tip.manualsAndProtocols":"by catalog number or product name","antibody.pdp.hero.advancedVerification":"Advanced Verification","antibody.searchresults.rowheader.productGrade":"Product Grade","antibody.pdp.productDetail.gstpulldown":"GST Pull Down","global.search.results.vectorCard.polylinker":"Polylinker","antibody.pdp.productDetail.functionalassay":"Functional Assay","antibody.pdp.productDetail.immunohistochemistryfreefloating":"Immunohistochemistry - Free Floating","antibody.searchresults.rowheader.your.price":"Your Price ","global.search.listName.required":"Please enter a list name.","global.search.results.cmgtProdCard.quickProductInfo":"Quick Product Info","common.search.modal.search.label.email":"Email Address (Optional):","global.search.results.citationCard.authors":"Authors","support.search.techSupport.navigation.softwareDownloads":"Software Downloads","microbe.zero.results.header":"Your search for {0} returned {1} TaqMan® Microbe \u0026 ABR Detection Assays","elisa.pdp.productdetails.interassaycv":"Interassay CV","antibody.pdp.reference.more":"more","global.search.results.didyoumean":"Your search for \u003cb\u003e{0}\u003c/b\u003e returned no results. Showing results for \u003cb\u003e{1}\u003c/b\u003e.","antibody.pdp.productDetail.immunohistochemistry":"Immunohistochemistry ","elisa.pdp.productdetails.targetsubspecificity":"Target sub-specificity","global.search.results.assayCard.find":"Find {0} that match your search term \"{1}\"","global.search.noResults.resources.support":"View all Product Support Documents","oligos.jpOligos.bulkUpload.uploadSelectFile":"Please select your upload file","immunoassay.elisa.zero.results.browse.all":"Browse all ","elisa.pdp.productdesc.let.us.know":"Let us know so we can reference it here.","antibody.pdp.productDetail.seepublishedapplication":"View {0} publication{1}","antibody.pdp.productDetail.immunocytochemistry":"Immunocytochemistry","antibody.pdp.footer.performanceGuaranteeTitle":"Performance Guarantee","oligos.jpOligos.deleteOligo.message":"Are you sure you want to do this?","antibody.serp.compare.rrid":"RRID","crispr.searchresults.rowheader.compare":"Compare","tout.whatIsSharedList.titleTxt":"What is a shared list?","antibody.searchresults.rowheader.price":"Price ","antibody.serp.compare.species":"Species","antibody.searchresults.row.publishedfigure":" Published Figure","antibody.pdp.productDetail.recommendedHostIsotype":"Recommended Isotype Control","info.tout.header.sharedList":"Introducing shared lists","global.search.secondaryResults.navigators.orderingWebFaq.nav1":"Categories","antibody.pdp.productDetail.mobilepublishedapplication":"{0} publication{1}","oligos.jpOligos.bulkUpload.fileUploadDescriptionNote":"Note: Procurement system users must save as a .csv or .txt file.","antibody.pdp.productDetail.fluorescentquenching":"Fluorescent Quenching","serp.filtertext.displayname.tissuetype":"Tissue Type","oligos.jpOligos.basicEntry.subHeader1":"Order using the tool below or","oligos.jpOligos.basicEntry.subHeader2":"up to 200 oligo sequences at one time.","oligos.jpOligos.addOligo.primerName":"Oligo Name *","antibody.pdp.productDetail.proteinbiology":"Protein biology","antibody.searchresults.row.signin.user.tooltip":"Sign in","global.search.filter.topLevelFilters":"FILTER RESULTS BY","global.search.results.vectorCard.sequence":"Sequence","antibody.serp.filter.keepMyFilter":"Keep filters for Search","elisa.searchresults.rowheader.samplevolume":"Sample Volume","common.wsp.tooltip.supply.center.info":"Web orders only.","antibody.serp.compare.quantity":"Quantity","elisa.pdp.productdetails.targetsitespeificity":"Target site-specificity","global.search.results.cmgtProdCard.rfq":"request a quote","global.search.form.search.text.validation.message":"Please enter a search term","antibody.tfp.desc.viewless":"View less","serp.panel.builder.adText":"Building a flow cytometry panel?","common.search.modal.faq.button.submit":"submit","antibody.pdp.bioinformatics.functions":"Function(s)","antibody.pdp.bioinformatics.geneAliases":"Gene Aliases:","antibody.searchresults.sop.ends":"Ends","global.search.results.coaCard.resultType":"Certificate of Analysis","global.search.results.cmgtProdCard.unitSize":"Unit Size","global.search.noResults.noResultsFoundForQuery":"We did not find results for: \u003cstrong\u003e${query}\u003c/strong\u003e. ","global.search.results.coaCard.download":"Download","oligos.jpOligos.bulkUpload.field.purity":"Purification *","antibody.pdp.productDetail.peptideelisa":"peptide-ELISA","oligos.jpOligos.addOligo.reverseOligo":"Reverse Oligo","microbe.zero.results.contact.two":"QuantStudioFrontDesk@thermofisher.com","support.search.form.searcharea.dropdown.label":"in","antibody.pdp.hero.createCitation":"Create Citation","support.search.placeholder.tip.faq":"by catalog number, product name or keyword","support.search.form.query.input.label":"With these keywords","antibody.serp.compare.form":"Form","global.sharedList.noListTxt":"Create your first list","unified.card.mirna.dna":"Branched DNA miRNA assays","serp.filtertext.displayname.targetspecies":"Target Species","antibody.pdp.commerceCard.onlineprice":"Online Price","antibody.pdp.productDetail.publishedApplication":"Publications","antibody.pdp.productDetail.notapplicable":"Not applicable","antibody.searchresults.rowheader.species":"Species","unified.card.elisa":"ELISA kits","elisa.crossSellCard.assayDevelopment.specific.protein":"We provide assay development of your specific protein target.","antibody.serp.filter.clonality":"Clonality","antibody.serp.filter.conjugate":"Conjugate","global.search.results.vectorCard.catNo":"Cat. No.","antibody.pdp.commerceCard.longtermunavailablemsg":"This product is temporarily unavailable.","antibody.searchresults.row.from.invitrogen":"({2} {3} from Invitrogen)","global.search.form.search.button":"Search","antibody.pdp.imageGallery.view.product":"View Product","oligos.jpOligos.addOligo.purity":"Purification *","serp.filtertext.displayname.ptm":"PTM","antibody.searchresults.row.sop.special.offer":"Special offer","info.modal.header.createsharedListHeader":"Creating a shared list","antibody.tfp.subheader.synonyms":"Synonyms","antibody.searchresults.compare.add.product.to.compare":"+ Add a product to compare","antibody.pdp.productDetail.dilution":"Tested Dilution","antibody.serp.filter.cross.adsorbed":"Cross Adsorbed","microbe.zero.results.reason.one":"The product has been discontinued.","crispr.zero.results":"Zero Results.","elisa.pdp.hero.about.this.kit":"About This Kit","oligos.jpOligos.common.buttons.confirm":"Confirm","global.search.results.cmgtProdCard.ratings.notYetRatedLabel":"Rate this product","global.search.sortingOptions.dateSort.default":"Relevancy","common.search.modal.faq.validation.required.expectations":"Please select your expectation","antibody.searchresults.row.mobile.filters":"Filters","elisa.pdp.productdetails.shippingcondition":"Shipping conditions","antibody.pdp.reference.heading":"References","oligos.jpOligos.bulkUpload.header":"Custom DNA Oligos","global.search.results.lullCard.catNo":"Catalog #","elisa.pdp.hero.references":" References","common.search.modal.faq.label.expectations.met":"Met","elisa.pdp.productdetails.contents":"Contents","unified.card.pcr":"PCR and Sanger sequencing primers","antibody.serp.compare.published.species.reactivity":"Published Species Reactivity","antibody.pdp.relatedProductsHeader":"Related Products","antibody.pdp.productDetail.antibody":"Antibody","antibody.pdp.productDetail.knockout":"KnockOut","antibody.pdp.productDetail.viewspectra":"View spectra","antibody.pdp.footer.performanceGuaranteeText":"If an Invitrogen™ antibody doesn\u0027\u0027\u0027t perform as described on our website or datasheet,we\u0027\u0027\u0027ll replace the product at no cost to you, or provide you with a credit for a future purchase.*","antibody.searchresults.row.sop.online.purchase.only":"Online exclusive","antibody.pdp.commerceCard.discontinuedmsg":"This product has been discontinued","common.search.modal.search.label.contactMe":"May we contact you?","antibody.serp.filter.species":"Species","antibody.serp.compare.product.information":"Product Information","antibody.pdp.productDetail.excitationemissionprofile":"Excitation/Emission Max","global.search.results.minipdp.msds.heading":"MSDS","antibody.serp.filter.more.filters":"More","antibody.pdp.productDetail.immunoblot":"Immunoblot","serp.flt.srch.nomatchfound":"No match found","serp.panel.builder.adText.tryPBcn":" ","global.search.results.citationCard.journal":"Journal","control.sitemap.description":"Isotype control antibodies to help differentiate signal from background. Wide selection of negative controls for Flow Cytometry, IHC, Immunopreciptation, ChIP and other applications. Select a target class to view all formats.","antibody.pdp.productDetail.productDetails":"Product Details","elisa.pdp.productdetails.assayrange":"Assay range","info.modal.header.exportsharedListHeader":"Export as a spreadsheet","oligos.jpOligos.addOligo.complementOligoName":"Complement Oligo Name*","elisa.pdp.product.specifications":"Product Specifications","antibody.serp.compare.purification":"Purification","support.search.techSupport.navigation.heading":"Technical Resources","global.search.results.minipdp.vectors.heading":"Vector Maps","antibody.pdp.productDetail.celltreatment":"Cell Treatment","antibody.pdp.commerceCard.notorderableonline":"Not orderable online","oligos.jpOligos.bulkUpload.templateDownloadDescription":"Upload your saved sequence file here (.xls, .csv, or .txt format only; .csv or .txt only if using a procurement system).","elisa.pdp.productdetails.handsontime":"Hands-on time","elisa.pdp.productdetails.storage":"Storage","global.search.results.coaCard.lotNo":"Lot #","global.search.secondaryResults.navigators.citations.nav1":"Citation Journal","serp.nav.tabs.secondary.antibodies":"Secondary Antibodies","elisa.pdp.productdetails.proteinname":"Protein name","antibody.zero.results.reason.two":"The {0} is listed under an alternate gene/protein name. Try searching for synonyms.","global.search.sortingOptions.dateSort.label":"Sort By","elisa.searchresults.rowheader.assayrange":"Assay Range","info.modal.header.sharedList":"About shared lists","serp.filtertext.displayname.kitformat":"Kit Format","global.search.results.genomicsHelperCard.assayId":"Assay ID","oligos.jpOligos.addOligo.sequence":"Oligo Sequence (5\u0027 to 3\u0027) *","antibody.pdp.productDetail.type":"Type","antibody.zero.results.other.subtype":"Zero results for \"{0}\" but we found \u003ca href\u003d\"{1}query/{0}\"\u003e{2} {3}\u003c/a\u003e that match your search.","elisa.pdp.productdetails.instrument":"Instrument","serp.filtertext.displayname.brand":"Brand","antibody.serp.footer.custom.service":"Custom Antibody Service","elisa.pdp.hero.viewOther":"View all ({0}) {1} ELISA Kits","antibody.pdp.bioinformatics.molecularFunctions":"Molecular Function:","crispr.zero.results.reason.five":"The designated gene has no predesigned guide RNAs. Contact","common.search.modal.faq.heading":"Provide Feedback on this Answer"}; $m.magellanConfig = {"PlatesEnabled":"yes","newUserDataAPI":"https://tfcommerce-api-eks.cloud.thermofisher.net/api/store/v1/users/details","redisReplica":"magellan-redis-prod-us-east-1-ro.8k5m7q.ng.0001.use1.cache.amazonaws.com:6379","uglifyElisaSerp":"true","displayAssaySelectionVideo":"true","promoCodeEnabled":"true","sharedListUserName":"mguser","requeryOnZeroResults":"true","mediaGalleryServerSideRender":"true","oligoBaseURL":"/order/custom-oligo","saveItemToListURL":"/shared-list/addItemToList/","relatedProductsWidgetV2":"true","useMagellanPricingAPI":"true","ComergentBasePathAdirect":"/order/catalog/en/US/adirect/lt?cmd\u003d","pathwaysQueryPath":"/order/genome-database/pathwaysQuery?keyword\u003d","targetDetailsFromMetadataHandlerEnabled":"true","biozRestEndpoint":"https://back-gene-8.bioz.com/get_widget_data_multi/","regionalizedHostForCom":"www.thermofisher.com","useNewRedisCluster":"false","UserTrackingEnabled":"false","enableFishersciPriceUrl":"true","domain":"LT","citeAbUrl":"https://widget.citeab.com/citations?key\u003d15f4e791-1de2-4fad-b413-70c8829ee4c2\u0026code\u003d","promotionAvailabilityAPI":"/api/store/coupons/eligiblePromos","saveItemToListUrlNew":"/shared-list/addItemToList","removeUserBasedCookies":"false","enableBioz":"true","newSearchFormFiltersEnabled":"true","availabilityApiNotEnabledCountries":"US;CA","mapDataServer":"/api/magellan/alignmap/map-server","tfpDescriptionPreviewWordSize":"100","applicationsBySortOrderEnabled":"true","secAntibodyAdditionalFormat":"ON","useAlternateObjectCache":"ON","configurationSource":"YAML","uglifyCommonSerp":"true","magWebSvcsBase":"http://magellan-data.prod.magellanprod.thermofisher.net/MagWebSvcs","webCacheStatus":"ON","queryWithQuotes":"false","pearExpVerAllocations":"12","aspireAntibodyLink":"/us/en/home/products-and-services/aspire-member-program.html?cid\u003dbid_asp_sbu_r02_co_cp1438_pjt7721_col015466_0wm_tfs_df_awa_at_s00_PCAAntibodyPDP2021","environmentConfig":"FrontEndAppServers,fastInstance,solrBaseUrl,genDBIdentifier,magWebSvcsBase,webMethodsBase,aimsSvcsBase,ComergentHost,assayValidationBase,assayDetailsServiceURL","ninetyNineImageCapEnabled":"true","maxSpellCheckOptionsToFetch":"5","clientId":"app-magellan-search","newFilterEnabledProductSubTypes":"ANTIBODY_PRIMARY,ANTIBODY_SECONDARY,ANTIBODY_CONTROL","resultCountForProductSubTypesForMobileAndTFP":"antibody_primary:10","uglifyLegacyScripts":"true","MirnaSiteSearchLinkEnabled":"true","uglifyCompare":"true","geneOntologyPageSize":"40","addExtraCookieEnabled":"false","promotionalAdAPI":"/product/v1/promopod/","imagesS3Enabled":"true","newLogInpath":"/auth/login","newUserDetailsAPI":"/api/store/customer/users/v1/","enableElisaQuoteForKeywordSearch":"true","solrBaseUrl":"https://magellan-solr-prod-blue-solrcloud.magellanprod.thermofisher.net/solr","antibodyFamilyRedirects":"OFF","resultCount":"25","imageSearchEnabled":"true","microbeAssayUrl":"/microbe-detection/taqman/query/","awsFileNameForRedirectUrlRegEx":"Url_Redirect_RegEx.json","jsUnifier":"ON","galleryFilterEnabled":"true","mixedFamilyBrandSearch":"true","crisprSERPURL":"/crispr/invitrogen/query/","showUnreleased":"OFF","isProductionEnvironment":"true","scrollUpMinRowTablet":"1","useOptimizedResources":"ANTIBODY;IMMUNOASSAY;sirna;ge-quantigene;microrna;ceprimer;GE;GT;CNV;MIRNA;DPCR;CRISPRSRE","pdpHijackDisabledProducts":"CRISPR,MICROBE","CrossSellConjugateRule":"*Common_Applications \u003c Conjugate \u003c TradeName ^ Conjugate \u003c TradeName + Conjugate \u003c SKU","spellCheckEnabled":"true","magellanPathwaysBaseURL":"https://magellan.tfcom-eks-na-magellanprod.magellanprod.thermofisher.net/order/magellan-pathways","default-genePartURL":"/gene","ComergentUserInfoAPI":"/api/store/user-type/","antigenCacheControlTimestamp":"20220613","pathwaysImagemapPath":"/rest/PathwayDetailService/imagemap/","inventoryLocationCountryLists":"UK-AT-BE-BG-HR-CZ-DK-EE-FI-FR-DE-GB-GR-HU-IS-IE-IL-IT-LT-LU-MT-NL-NO-PL-PT-RO-SK-ES-SE-CH-TR","brightCovePanelBuilderVideoId":"6206990159001","ApplicationHost":"www.thermofisher.com","pantherPageSize":"40","techSupportEnabledCountries":"us;ca","availableReplicatesMCRB":"1,2,3,4,5,6","ComergentBasePath":"/order/catalog/en/US/direct/lt?cmd\u003d","aimsSvcsBase":"http://f1opd.corp.life:8080/aims-rest-service","spellCheckDisplayCount":"3","newPricingApi":"/api/magellan/pricing/","microbeEnabled":"true","awsRegion":"us-east-1","pricingAPICallGroupDelay":"200","custom_id_api_host":"/order/custom-genomic-products","DBSNPUrl":"//www.ncbi.nlm.nih.gov/projects/SNP","createOrRetrieveCartService":"https://tfcommerce-api-eks.cloud.thermofisher.net/api/store/carts/tp/retrieveCart?cartName\u003d","crsprTrueguideEnabled":"YES","unifiedAntibodySearchEnabled":"false","enableNewHeaderFooterForFisherSciForEU":"true","fisherSciStaticHost":"beta-static.fishersci.com","pricingWebWorkerEnabled":"true","useLegacyJsLibraries":"true","default-productPartURL":"/details","emailNotificationList":"marty.sherrill@lifetech.com","uglifyAntibodySerp":"true","aimsDescriptionServiceURL":"http://f1opd.corp.life:8080/aims-rest-service/descriptionForName","scrollUpMinRowMobile":"1","ComergentBasePathEntMgr":"/order/catalog/en/US/enterpriseMgr/lt?cmd\u003d","ApplicationHost-FISHERSCI_US":"www.fishersci.com","SolrEnabledProducts":"IMMUNO_ASSAY, ANTIBODY_TF, CRISPR_TF, MICROBE_TF, GENOTYPING","newAvailabilityApiEnabledCountries":"CN;KR;UK;AT;BE;BG;CM;HR;CZ;DK;EG;EE;FI;FR;GE;DE;GB;GR;HU;IS;IE;IL;JO;KZ;KE;LV;IT;LT;LU;MT;NL;NO;PL;PT;QA;RE;RO;RU;RS;SK;SI;ZA;ES;SE;CH;TN;TR;UA;AE","newPricingApiEnabledProducts":"ANTIBODY;IMMUNOASSAY","MyAvailabilityAPI":"/order/catalog/en/US/partnerMkt/lt?cmd\u003dvalidateAuthentication\u0026targetMessageType\u003dcommercePodOperations\u0026operation\u003dAvailability","HotJarID":"4539","coreRedisCacheTTLs":"productPDPHijackURL:604800,RelatedArraysCountCache:86400,KeywordGeneDataCache:86400,packageDataCache:90000,myPriceDataCache:43200,familyPageDetailsCache:86400,elisaFamilyPageDetailsCache:86400,antigenCountOnTFP:604800,catalogItemCache:86400,redirectProducts:-1,globalSearchResultsCache:86400","keepMyFiltersEnabled":"true","elisaSolrReQueryDisabled":"false","DomainName":"thermofisher.com","awsFolderNameForRedirectUrl":"productlist/","enableAdobeLaunch":"true","genePageSize":"100","secondaryConjugateOrder":"Functional Grade,Unconjugated,Biotin,AP,FITC,DyLight,Alexa Fluor,HRP,All Conjugates","pricingCacheMaxAge":"43200","techSupportModalEnabled":"true","isNewUserDataAPIEnabled":"false","dayServerBaseURL":"www.thermofisher.com","FASTSearchViewCache":"ON","brightcoveAccountId":"3663210762001","newAvailabilityAPI":"/api/store/sku/availability/","targetPageVideoEnabled":"true","chatEnabled":"false","catalogSearchEnabled":"true","ApplicationHost-fishersci":"www.fishersci.com","Authorization":"Bearer eyJ0eXAiOiJKV1QiLCJhbGciOiJIUzI1NiJ9.eyJpc3MiOiJ3d3cudGhlcm1vZmlzaGVyLmNvbSIsImlhdCI6OTQ2Njg0ODAwLCJleHAiOjQwNzA5MDg4MDAsImF1ZCI6Ind3dy50aGVybW9maXNoZXIuY29tIiwic3ViIjoibWFnZWxsYW4ifQ.cHEqJM4Z9C8r_p4q8bJBAcj2SKdjqITlGkhHor9_Eig","headerFooterStyle":"DYNAMIC","awsBucketNameForRedirectUrl":"magellan-url-redirects-prod","microbeGlobalDyeSizeEnable":"false","jpPearUXVerAllocations":"2","relatedProductsEnabledProductSubTypes":"ANTIBODY_PRIMARY, ANTIBODY_SECONDARY, ANTIBODY_CONTROL","newAvailabilityAPIWithOAuth2":"/api/store/product/availability/v1/","advVerificationTag":"true","catalogAPI":"/api/store/product/catalog/v1/","fastInstance":"uspgh-tfmfa2-p2.amer.thermo.com:15100,uspgh-tfmfa2-p3.amer.thermo.com:15100,uspgh-tfmfa2-p4.amer.thermo.com:15100","resultCountForProductSubTypes":"antibody_primary:25,antibody_secondary:25,antibody_control:50,antibody_protein:50,elisa:50","allowShowMoreShowLess":"false","ComergentHost":"www.thermofisher.com","crsprEnabled":"YES","hideStackTracesInLogs":"false","catalogClientSecretKey":"magellan/prod/catalog-client-secret","tfpDescriptionPreviewConfig":"sm:66,700;md:110,500;lg:132,900","magellanPricingAPIPath":"/api/magellan/pricing/","customSearchAPI":"/api/magellan/product/customSearch","fishersci-priceUrl":"https://www.fishersci.com/shop/service/price","maxSKUsInPricingCall":"20","pearUXVerAllocations":"2","metadataHandlerEnabledProductSubTypes":"ANTIBODY_PRIMARY,ANTIBODY_SECONDARY,ELISA,ANTIBODY_PROTEIN","imageSearchEnabledSubTypes":"ANTIBODY_PRIMARY,ANTIBODY_SECONDARY","addToCartService":"http://tfcom-api.cloud.thermofisher.net/api/store/third-party-addtocart/add","elcanoNewToolEnabledProducts":"ge:ST,ge:PT,genotyping:ST,cnv:ST","useGlobalStyles":"ON","AntibodiesEuropeanCountryList":"UK-AT-BE-BG-CM-HR-CZ-DK-EG-EE-FI-FR-GE-DE-GB-GR-HU-IS-IE-IL-JO-KZ-KE-LV-IT-LT-LU-MT-NL-NO-PL-PT-QA-RE-RO-RU-RS-SK-SI-ZA-ES-SE-CH-TN-TR-UA-AE","bulkQuoteCustomFormPricingApiPath":"/fields/specifications,antibodyCustomForms","techSupportExtUrlForConjugatedPAB":"true","briefXmlFlag":"false","genomicProductSearchQueryPath":"/order/genome-database/genomicProductsQuery?keyword\u003d","siteSearchQueryPath":"/search/service/results?query\u003d","elisaPageSize":"80","pricingApiTimeout":"10000","primaryConjugateOrder":"Agarose,Functional Grade,Unconjugated,All Conjugates","newCatalogAPI":"https://tfpc-catalog.qa1.cloudqa.thermofisher.net/api/store/sku?catalogNumbers\u003d","multiplexEnabled":"NO","citeAbEnabled":"true","referenceCount":"true","crossContextHeaderFooter":"OFF","flexiblePanelAssayTypes":"sirius,tlda,tap1,tap2,beamr,tesli,teslc","newTFPProteinUrlEnabled":"true","promoAdEnabledSubTypes":"ANTIBODY_PRIMARY,ANTIBODY_SECONDARY,ANTIBODY_CONTROL,ANTIBODY_PROTEIN,ELISA","pricingCallTimeoutSeconds":"10","enableBadges":"false","ComergentCookiePath":"/order","siteSearchProductApiTimeout":"5000","scrollUpMinRow":"1","debugProductSiteRegion":"false","epitopesModalImageMultiSizeEnabled":"true","antigenSearchEnabledSubTypes":"ANTIBODY_PRIMARY","regionalizedHostForCn":"www.thermofisher.cn","uglifyCoreScript":"true","useResponsiveOptIn":"false","enableProductSiteLogger":"false","newAvailabilityAPIWithOAuth2Enabled":"true","pearCookiesReductionEnabled":"true","browserCacheControl":"OFF","newGshEnabled":"true","filtersUrlEnabledProducts":"antibody;crispr;immunoassay;microbe","pearUXCookieName":"pearUXVerMar","panelBuilderMagWebApi":"http://magellan-data.prod.magellanprod.thermofisher.net/MagWebSvcs/PanelBuilder.jsp","EHCache_memory_setting":"ehcache-aws-prod","orderedApplications":"WB,IHC,IHC (P),IHC (PFA),IHC (F),IHC (Free),ICC/IF,ICC,IF,Flow,ELISA,IP,ChIP,ChIP-seq,Neu,FN,LUM,RIA,Ctrl,PLA,ARRAY,DB,IM,IA,GS,pep-ELISA,IDF,RIP,BLOCK,IE,TCA,LF,AGG,ISH,CT,HA,AP,IV,FQ,CA,IRMA,WB-Ag,GPD,FRET,MISC","HeaderFooterMicroServiceHost":"tfpt-header-footer.tfcom-eks-na-comerce-gateway-prd.commerceprod.thermofisher.net","fishersci-newpriceUrlEU":"api.fishersci.eu/fishersci-pricing/priceandavail","referenceSortByFilterRemoved":"true","compareAnalyticsEnabled":"true","enableNjord":"false","JapanPVNOEnabledForOnlinePrice":"true","qandaEnabledProductSubTypes":"ANTIBODY_PRIMARY, ANTIBODY_SECONDARY, ANTIBODY_CONTROL","fullSizeImageEnabled":"true","oldFischerSciPricingUrl":"shop/service/price","pathwaysApplicationBase":"https://magellan.tfcom-eks-na-magellanprod.magellanprod.thermofisher.net","enableShippingCondition":"true","filterSearchEnabled":"true","useMinifiedAssets":"false","adminEmail":"magellan.life@gmail.com","enablePdltMessage":"false","qnaWidgetAPI":"/api/magellan/qanda-ui/qna/widget/","hideTooltipForNewAvailabilityCountries":"CN","usePreloadedJS":"true","elcanoNewToolEnabled":"true","AssayDetailsServiceWarningThreshold":"3000","assayValidationBase":"http://f1opd.corp.life:8080/AssayValidation","ThirdPartySolrEnabledProducts":"ANTIBODY_TF","enableArrayConfiguratorCVIT":"true","thermoNonDotComEnabledCountries":"cn","magellanSearchFilter":"true","biozURL":"//nlpsearch-ptenlab-gene-8.appspot.com","tppEndCapEnabled":"false","techSupportModalEnabledSubTypes":"ANTIBODY_PRIMARY;ANTIBODY_SECONDARY;ANTIBODY_CONTROL","getAntigenCountInBackend":"true","newLogOutpath":"/auth/logout","hostName":"magellan-search-blue-5c9c5c4749-97l6p","enableProductTabsForMicrobe":"true","uglifyVendorScripts":"true","eksCluster":"magellan.tfcom-eks-na-magellanprod.magellanprod.thermofisher.net","allowCommergentHostOverrides":"false","assaysEuropeanCountryList":"N/A","newTypeAheadEnabledProductSubTypes":"ANTIBODY_PRIMARY,ELISA","usePatternLibrary":"OFF","CmgtAddToCartService":"IVGNThirdPartyAddToCart","useRedis":"true","qnaLoaderThreshold":"#tf-related-products-container","errorLogDBInstance":"orcl_pri_gart","updateRegionalizedCanonicalUrlHost":"true","brightcoveApiSecretName":"magellan/prod/bcovpolicykey","SpeciesSortRelevancy":"ON","baseCatalogApi":"tfcommerce-api-eks-prod.commerceprod.thermofisher.net","ge-productPartURL":"/taqman-gene-expression/product","antigenSearchEnabled":"true","relatedProductsModuleURL":"/api/magellan/related-products-ui/widget/","techSupportExtUrl":"/home/technical-resources/contact-us/ext-antibody-technical-support","enablePrimaryEpitopeSrch":"true","assayIdsCount":"10","newTypeAheadEnabled":"true","redisCacheTTLs":"productPDPHijackURL:604800,RelatedArraysCountCache:86400,KeywordGeneDataCache:86400,packageDataCache:90000,myPriceDataCache:43200,familyPageDetailsCache:86400,elisaFamilyPageDetailsCache:86400,antigenCountOnTFP:604800,catalogItemCache:86400,redirectProducts:-1,globalSearchResultsCache:86400","ABPortalBaseURL":"(obsolete)","fastInstanceKey":"com.fastsearch.esp.search.http.qrservers","referenceFilterEnabled":"true","embeddedSearchFormDelay":"50","build-date":"2024-11-22T02:34:09Z","googleKey":"lW0Xt-iQmhGMfRn12R1YjbD1","KongGateway":"https://api.thermofisher.com","enableEstimatedAvailability":"true","qnaEnabledCountries":"CA,US","ComergentFilePath":"/order/catalog/en/US/css/ivgn/","biozHome":"https://www.bioz.com/tf_widget/","coreBuyerEmailAddress":"rashwor2@jhmi.edu,customorders@jhmi.edu,Manuel.Paniagua@thermofisher.com,Jose.Gutierrez@thermofisher.com,dave.kim@thermofisher.com","configurationInstance":"aws-prod-blue","newSourceIDToggle":"true","k8s-app-name":"magellan-search","CrossSellDbInstance":"orcl_pri_gart","solrSkuHijackEnabled":"true","enableOTMM":"true","sharedListURL":"/shared-list/getLists/","FisherSciEuropeanCountryList":"AT-BE-DK-FR-FI-DE-IE-IT-NL-NO-PT-ES-SE-CH-UK","medalliaEmbedJsToggle":"false","primaryPTMOrder":"Phosphorylated,Methylated,Acetylated,None","sequenceSearchServiceURL":"http://wmprd.thermofisher.com:5555/invoke/Life_GenomicsDesigns.process/receiveXML","newAvailabilityApiEnabled":"true","qnaModuleEnabled":"true","allConjugateEnabledProductSubTypes":"ANTIBODY_PRIMARY,ANTIBODY_SECONDARY,ANTIBODY_CONTROL","debugMode":"OFF","redirectToSiteSearchForMagellanZR":"false","sharedListsURL":"/us/en/home/technical-resources/ordering-web-faqs/shopping-cart-checkout/how-to-order/order.html#container-217a2","awsFileNameForRedirectUrl":"URL_Redirects.xlsx","productSearchCountAPI":"/api/magellan/product-service/getProductSearchCount?keyword\u003d","newGlobalSearchAPIEnabled":"true","HttpProtocol":"https://","elcanoNewToolBasePath":"/taqman","keywordTypeaheadBaseURL":"https://magellan.tfcom-eks-na-magellanprod.magellanprod.thermofisher.net/solr/lt-magellan-search-core/select","1000GenomesUrl":"//www.ncbi.nlm.nih.gov/variation/tools/1000genomes","jpPearExpVerAllocations":"1","enableNewHeaderFooter":"true","useFisherSciMfgPart":"false","MicrobeConfiguratorPath":"/microbe-detection/taqman/target-list/array-configurator-open","sharedListEligibleURL":"/order/catalog/msg/lt/rest/adirect/countries/SharedListEligible/","pathwaysReferencesPath":"/rest/PathwayDetailService/references/","pathwaysDescriptionPath":"/rest/PathwayDetailService/description/","benchSciImageLimit":"40","hideGeneDetailsProdTypes":"taqman,ge,plate,genotyping,cnv,microrna,dpcr,mutation,sirna,antibody","maxNoOfPublishedImages":"40","enableSOLRSearch":"true","redisMaster":"magellan-redis-prod-us-east-1.8k5m7q.ng.0001.use1.cache.amazonaws.com:6379","pubmedUrl":"http://pubmed.ncbi.nlm.nih.gov/pubmed/","loggingLevel":"DEBUG","pearExpSetupCookies":"NA","alternateSEOUrl":"EN-US;ZH-CN;EN-CN;x-default","bannerMessagesEnabled":"true","antibodyCacheControlTimestamp":"20240507","uglifyCommonPrimaryScripts":"true","ComergentProductPath":"/order/catalog/product/","isTfKongEnabled":"true","catalogAPIGatewayWithOauth2Enabled":"true","kongCreateCartService":"/api/store/carts/tp/retrieveCart","maxKeywordLength":"250","packageSource":"LT","enableJPSpecificStyle":"false","ProtectedBatchSearchMode":"OFF","newDocumentsApiExpanded":"true","newPricingApiDisabledCountries":";","ConfigurationSource":"YAML/aws-prod-blue/pgres_pri_gart_new","technicalSupportContactURL":"/global/en/home/technical-resources/contact-us.html","hostIp":"100.66.76.85","cacheStatus":"ON","userProfileService":"http://tfcom-api.cloud.thermofisher.net/api/store/v1/users/basicDetails","redirectUrlEnabled":"false","relatedProductsEnabled":"true","x-application":"magellan","chinaSupplyCenterEnabled":"true","proteinPageSize":"80","assayValidationApi":"http://f1opd.corp.life:8080/AssayValidation/processXml","videoInImageGalleryToggle":"true","HeaderFooterHost":"www.thermofisher.com","renderHeaderFooterViaSSI":"true","cacheControlTimestamp":"20240917","kongCartAddService":"/api/store/ordering/cart/v1","enableSop":"true","newDocumentsApiEnabled":"true","TargetRedirectEnabled":"true","keepMyFiltersEnabledSubTypes":"ANTIBODY_PRIMARY,ANTIBODY_SECONDARY,ANTIBODY_CONTROL,ANTIBODY_PROTEIN,ELISA","aspireElisaLink":"/us/en/home/products-and-services/aspire-member-program.html?cid\u003dbid_asp_sbu_r02_co_cp1438_pjt7721_col015466_0wm_tfs_df_awa_at_s00_PCAELISAPDP2021","citationLinks":"5","enableBulkQuoteCustomForm":"true","awsMetadataURL":"http://169.254.169.254/latest/meta-data/local-ipv4","webMethodsBase":"http://wmprd.thermofisher.com:5555","ge-genePartURL":"/taqman-gene-expression/gene","fischerSciPricingUrl":"fishersci-pricing/priceandavail","enableNewHeaderFooterForFisherSci":"true","allConjugateCountThreshold":"5","assayStatusServiceURL":"http://magellan-data.prod.magellanprod.thermofisher.net/MagWebSvcs/AssayStatus.jsp","magellanPricingAPILogs":"false","pdpProductSchemaEnabled":"true","regionalizedEnabledCountries":"CN","elisaTFPEnabled":"true","techSupportExtUrlForUnConjugatedPAB":"true","specialOfferPricingEnabledCountries":"US;CA;FI;ZA;DK;ES;NL;UK;OM;AT;CZ;HU;BG;FR;SI;SE;JO;LB;NO;CH;IE;PL;RO;BE;MK;MT;EG;GR;HR;SK;RS;AL;BA;BH;KW;KE;GB;DE;IT;IQ;QA;AE;SA;LY;ME;YE;CY;IL;PT;AD;AF;AI;AM;AO;AS;AW;AZ;BF;BI;BJ;BV;BW;BY;CC;CF;CG;CI;CM;CV;CX;DJ;DZ;EE;EH;ER;ET;FK;FO;FX;GA;GE;GF;GH;GL;GM;GN;GP;GQ;GS;GW;HM;IM;IO;IS;KG;KI;KM;KN;KZ;LC;LR;LS;LT;LU;LV;MA;MC;MD;MG;ML;MN;MQ;MR;MU;MW;MZ;NA;NC;NE;NF;NG;NR;NU;PF;PM;PN;PS;PW;RE;RU;RW;SB;SC;SH;SJ;SL;SM;SN;ST;SZ;TC;TD;TF;TG;TJ;TK;TM;TN;TR;TV;TZ;UA;UG;UZ;VA;VC;VG;VU;WF;YT;ZM;ZW","formatFilterEnabled":"true","useNewBrightCoveVideoPlayer":"true","genDBIdentifier":"orcl_pri_gen2","sharedListUserPwd":"mgprd@user","fisherSciSearchFormPageId":"IU5R4C73","chatBaseApiUrl":"https://chat-api.thermofisher.com","schemaMarkupEnabledForSERP":"true","newComparePanelEnable":"true","schemaMarkupEnabled":"true","spectraHost":"/order/fluorescence-spectraviewer","newChatGateWayEnabled":"false","searchXmlServiceURL":"http://magellan-data.prod.magellanprod.thermofisher.net/MagWebSvcs/AssayAnnotSearch.jsp","pearUXSetupCookies":"NA","IVGNaddToCartServiceURL":"/order/catalog/en/US/adirect/lt?cmd\u003dIVGNThirdPartyAddToCart","outboundEmailServer":"smtp.cloud.thermofisher.net","siteSearchProcessTimeout":"100","filterSearchExactFacetEnabled":"false","magellanClusterBaseURL":"https://magellan.tfcom-eks-na-magellanprod.magellanprod.thermofisher.net","pathwaysDetailsPath":"/rest/PathwayDetailService/detail/","translationEnabledProducts":"antibody;immunoassay","solrReQueryDisabled":"true","techSupportModalEmailFormUrl":"/home/technical-resources/contact-us/antibody-technical-support","geneDetailDataEnabled":"true","panelBuilderResultCount":"300","customToolBaseURL_sansProtocol":"/order/custom-genomic-products","redisSecret":"magellan/redis","lucidWorksAPIHostURL":"tfsearch-store-nginx-prod.srchcloudprod.thermofisher.net","newProteinUrlEnabled":"true","FrontEndAppServers":"http://magellan-srch-1-prod-blue.cloud.thermofisher.net:8080~~~http://magellan-srch-2-prod-blue.cloud.thermofisher.net:8080~~~http://magellan-srch-3-prod-blue.cloud.thermofisher.net:8080","userDataAPI":"http://tfam-users.prod.cloud.thermofisher.net/api/store/users/details","inventoryDataServiceUrl":"http://magellan-data.prod.magellanprod.thermofisher.net/MagWebSvcs/AssayInvLoc.jsp","pdltApplicableCountryList":"KR;CN","ApplicationBasePath":"/order/genome-database","spellCheckKeywords":"{\u0027keywords\u0027: [{\u0027antibody\u0027: \u0027anibody;anitbody;antabody;antbodie;antbody;anti-body;antibode;antibodi;antobody\u0027}]}","CommerceServiceYourPricePerSKUWarningThreshold":"5000","skuSummary":"/search/api/summary/sku/en/US/","assayDetailsServiceURL":"http://magellan-data.prod.magellanprod.thermofisher.net/MagWebSvcs/AssayAnnot.jsp","microbeBatchTermsLimit":"1000","mixedBrandSearch":"true","showUnentitled":"OFF","enableNewPricingTooltip":"true","sortSpellCheckCollations":"true","moveJqueryToBody":"true","blockPooledAssaysFormat":"TACMIRNA,SIRIUS,TLDA,TAP2,TAP1","packageServiceURL":"http://magellan-data.prod.magellanprod.thermofisher.net/MagWebSvcs/Package.jsp","crisprV2Enabled":"true","CommerceServiceListPricePerSKUWarningThreshold":"2000","fishersci-newpriceUrlUS":"api.fishersci.com/fishersci-pricing/priceandavail","categoryPageServiceURL":"http://magellan-data.prod.magellanprod.thermofisher.net/MagWebSvcs/GenomicListData.jsp","elisaImageGalleryToggle":"true","FisherSciEuropeanDomain":"www.fishersci"}; $m.countryCode = ""; // to point the header urls to local.thermofisher.com for local environment if ("aws-prod-blue".toLowerCase() === "local") { window.environmentURL.WCMSERVER = $m.magellanConfig['ApplicationHost']; } </script> </body> </html>