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<!DOCTYPE html> <html lang="en" class="no-js"> <head> <meta charset="UTF-8"> <meta http-equiv="X-UA-Compatible" content="IE=edge"> <meta name="applicable-device" content="pc,mobile"> <meta name="viewport" content="width=device-width, initial-scale=1"> <meta name="robots" content="max-image-preview:large"> <meta name="access" content="No"> <meta name="360-site-verification" content="1268d79b5e96aecf3ff2a7dac04ad990" /> <title>Proteins with antifungal properties and other medicinal applications from plants and mushrooms | Applied Microbiology and Biotechnology</title> <meta name="twitter:site" content="@SpringerLink"/> <meta name="twitter:card" content="summary_large_image"/> <meta name="twitter:image:alt" content="Content cover image"/> <meta name="twitter:title" content="Proteins with antifungal properties and other medicinal applications from plants and mushrooms"/> <meta name="twitter:description" content="Applied Microbiology and Biotechnology - Living organisms produce a myriad of molecules to protect themselves from fungal pathogens. This review focuses on antifungal proteins from plants and..."/> <meta name="twitter:image" content="https://media.springernature.com/full/springer-static/cover-hires/journal/253"/> <meta name="journal_id" content="253"/> <meta name="dc.title" content="Proteins with antifungal properties and other medicinal applications from plants and mushrooms"/> <meta name="dc.source" content="Applied Microbiology and Biotechnology 2010 87:4"/> <meta name="dc.format" content="text/html"/> <meta name="dc.publisher" content="Springer"/> <meta name="dc.date" content="2010-06-08"/> <meta name="dc.type" content="ReviewPaper"/> <meta name="dc.language" content="En"/> <meta name="dc.copyright" content="2010 Springer-Verlag"/> <meta name="dc.rights" content="2010 Springer-Verlag"/> <meta name="dc.rightsAgent" content="journalpermissions@springernature.com"/> <meta name="dc.description" content="Living organisms produce a myriad of molecules to protect themselves from fungal pathogens. This review focuses on antifungal proteins from plants and mushrooms, many of which are components of the human diet or have medicinal value. Plant antifungal proteins can be classified into different groups comprising chitinases and chitinase-like proteins, chitin-binding proteins, cyclophilin-like proteins, defensins and defensin-like proteins, deoxyribonucleases, embryo-abundant protein-like proteins, glucanases, lectins, lipid transfer proteins, peroxidases, protease inhibitors, ribonucleases, ribosome-inactivating proteins, storage 2S albumins, and thaumatin-like proteins. Some of the aforementioned antifungal proteins also exhibit mitogenic activity towards spleen cells, nitric oxide inducing activity toward macrophages, antiproliferative activity toward tumor cells, antibacterial activity, and inhibitory activity toward HIV-1 reverse transcriptase. In contrast to the large diversity of plant antifungal proteins, only a small number of mushroom antifungal proteins have been reported. Mushroom antifungal proteins are distinct from their plant counterparts in N-terminal sequence. Nevertheless, some of the mushroom antifungal proteins have been shown to inhibit HIV-1 reverse transcriptase activity and tumor cell proliferation."/> <meta name="prism.issn" content="1432-0614"/> <meta name="prism.publicationName" content="Applied Microbiology and Biotechnology"/> <meta name="prism.publicationDate" content="2010-06-08"/> <meta name="prism.volume" content="87"/> <meta name="prism.number" content="4"/> <meta name="prism.section" content="ReviewPaper"/> <meta name="prism.startingPage" content="1221"/> <meta name="prism.endingPage" content="1235"/> <meta name="prism.copyright" content="2010 Springer-Verlag"/> <meta name="prism.rightsAgent" content="journalpermissions@springernature.com"/> <meta name="prism.url" content="https://link.springer.com/article/10.1007/s00253-010-2690-4"/> <meta name="prism.doi" content="doi:10.1007/s00253-010-2690-4"/> <meta name="citation_pdf_url" content="https://link.springer.com/content/pdf/10.1007/s00253-010-2690-4.pdf"/> <meta name="citation_fulltext_html_url" content="https://link.springer.com/article/10.1007/s00253-010-2690-4"/> <meta name="citation_journal_title" content="Applied Microbiology and Biotechnology"/> <meta name="citation_journal_abbrev" content="Appl Microbiol Biotechnol"/> <meta name="citation_publisher" content="Springer-Verlag"/> <meta name="citation_issn" content="1432-0614"/> <meta name="citation_title" content="Proteins with antifungal properties and other medicinal applications from plants and mushrooms"/> <meta name="citation_volume" content="87"/> <meta name="citation_issue" content="4"/> <meta name="citation_publication_date" content="2010/07"/> <meta name="citation_online_date" content="2010/06/08"/> <meta name="citation_firstpage" content="1221"/> <meta name="citation_lastpage" content="1235"/> <meta name="citation_article_type" content="Mini-Review"/> <meta name="citation_language" content="en"/> <meta name="dc.identifier" content="doi:10.1007/s00253-010-2690-4"/> <meta name="DOI" content="10.1007/s00253-010-2690-4"/> <meta name="size" content="315576"/> <meta name="citation_doi" content="10.1007/s00253-010-2690-4"/> <meta name="citation_springer_api_url" content="http://api.springer.com/xmldata/jats?q=doi:10.1007/s00253-010-2690-4&api_key="/> <meta name="description" content="Living organisms produce a myriad of molecules to protect themselves from fungal pathogens. This review focuses on antifungal proteins from plants and mush"/> <meta name="dc.creator" content="Wong, Jack H."/> <meta name="dc.creator" content="Ng, T. B."/> <meta name="dc.creator" content="Cheung, Randy C. F."/> <meta name="dc.creator" content="Ye, X. J."/> <meta name="dc.creator" content="Wang, H. X."/> <meta name="dc.creator" content="Lam, S. K."/> <meta name="dc.creator" content="Lin, P."/> <meta name="dc.creator" content="Chan, Y. S."/> <meta name="dc.creator" content="Fang, Evandro F."/> <meta name="dc.creator" content="Ngai, Patrick H. K."/> <meta name="dc.creator" content="Xia, L. X."/> <meta name="dc.creator" content="Ye, X. Y."/> <meta name="dc.creator" content="Jiang, Y."/> <meta name="dc.creator" content="Liu, F."/> <meta name="dc.subject" content="Microbiology"/> <meta name="dc.subject" content="Microbial Genetics and Genomics"/> <meta name="dc.subject" content="Biotechnology"/> <meta name="citation_reference" content="citation_journal_title=J Mol Microbiol Biotechnol; citation_title=The antifungal activity of RsAFP2, a plant defensin from Raphanus sativus, involves the induction of reactive oxygen species in Candida albicans ; citation_author=AM Aerts, IE François, EM Meert, QT Li, BP Cammue, K Thevissen; citation_volume=1; citation_publication_date=2007; citation_pages=243-247; citation_id=CR1"/> <meta name="citation_reference" content="citation_journal_title=Cell Mol Life Sci; citation_title=The mode of antifungal action of plant, insect and human defensins; citation_author=AM Aerts, IE François, BP Cammue, K Thevissen; citation_volume=65; citation_publication_date=2008; citation_pages=2069-2079; citation_id=CR2"/> <meta name="citation_reference" content="citation_journal_title=FEBS Lett; 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citation_title=Isolation and characterization of an immunosuppressive protein from Trichosanthes kirilowii root tubers; citation_author=HW Yeung, SP Poon, NG TB, WW Li; citation_volume=9; citation_publication_date=1987; citation_pages=25-46; citation_id=CR139"/> <meta name="citation_reference" content="citation_journal_title=Mol Cell; citation_title=Osmotin, a plant antifungal protein subverts signal transduction to enhance fungal cell susceptibility; citation_author=DJ Yun, JI Ibeas, H Lee, MA Coca, ML Narasimham, Y Uesono, PM Hasegawa, JM Pardo, RA Bressan; citation_volume=1; citation_publication_date=1998; citation_pages=807-817; citation_id=CR140"/> <meta name="citation_author" content="Wong, Jack H."/> <meta name="citation_author_institution" content="The School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, New Territories, China"/> <meta name="citation_author" content="Ng, T. B."/> <meta name="citation_author_email" content="b021770@mailserv.cuhk.edu.hk"/> <meta name="citation_author_institution" content="The School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, New Territories, China"/> <meta name="citation_author" content="Cheung, Randy C. F."/> <meta name="citation_author_institution" content="The School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, New Territories, China"/> <meta name="citation_author" content="Ye, X. J."/> <meta name="citation_author_institution" content="The School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, New Territories, China"/> <meta name="citation_author" content="Wang, H. X."/> <meta name="citation_author_email" content="hxwang@cau.edu.cn"/> <meta name="citation_author_institution" content="State Key Laboratory of Agrobiotechnology, Department of Microbiology, China Agricultural University, Beijing, China"/> <meta name="citation_author" content="Lam, S. K."/> <meta name="citation_author_institution" content="The School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, New Territories, China"/> <meta name="citation_author" content="Lin, P."/> <meta name="citation_author_institution" content="The School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, New Territories, China"/> <meta name="citation_author" content="Chan, Y. S."/> <meta name="citation_author_institution" content="The School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, New Territories, China"/> <meta name="citation_author" content="Fang, Evandro F."/> <meta name="citation_author_institution" content="The School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, New Territories, China"/> <meta name="citation_author" content="Ngai, Patrick H. K."/> <meta name="citation_author_institution" content="Department of Biochemistry, Faculty of Science, The Chinese University of Hong Kong, New Territories, China"/> <meta name="citation_author" content="Xia, L. X."/> <meta name="citation_author_email" content="xialixin@126.com"/> <meta name="citation_author_institution" content="College of Medicine, Shenzhen University, Shenzhen, China"/> <meta name="citation_author" content="Ye, X. Y."/> <meta name="citation_author_institution" content="College of Biological Science and Technology, Fuzhou University, Fuzhou, China"/> <meta name="citation_author" content="Jiang, Y."/> <meta name="citation_author_institution" content="Department of Microbiology, College of Life Sciences, Nankai University, Tianjin, China"/> <meta name="citation_author" content="Liu, F."/> <meta name="citation_author_institution" content="Department of Microbiology, College of Life Sciences, Nankai University, Tianjin, China"/> <meta name="format-detection" content="telephone=no"/> <meta name="citation_cover_date" content="2010/07/01"/> <meta property="og:url" content="https://link.springer.com/article/10.1007/s00253-010-2690-4"/> <meta property="og:type" content="article"/> <meta property="og:site_name" content="SpringerLink"/> <meta property="og:title" content="Proteins with antifungal properties and other medicinal applications from plants and mushrooms - Applied Microbiology and Biotechnology"/> <meta property="og:description" content="Living organisms produce a myriad of molecules to protect themselves from fungal pathogens. This review focuses on antifungal proteins from plants and mushrooms, many of which are components of the human diet or have medicinal value. Plant antifungal proteins can be classified into different groups comprising chitinases and chitinase-like proteins, chitin-binding proteins, cyclophilin-like proteins, defensins and defensin-like proteins, deoxyribonucleases, embryo-abundant protein-like proteins, glucanases, lectins, lipid transfer proteins, peroxidases, protease inhibitors, ribonucleases, ribosome-inactivating proteins, storage 2S albumins, and thaumatin-like proteins. Some of the aforementioned antifungal proteins also exhibit mitogenic activity towards spleen cells, nitric oxide inducing activity toward macrophages, antiproliferative activity toward tumor cells, antibacterial activity, and inhibitory activity toward HIV-1 reverse transcriptase. In contrast to the large diversity of plant antifungal proteins, only a small number of mushroom antifungal proteins have been reported. Mushroom antifungal proteins are distinct from their plant counterparts in N-terminal sequence. Nevertheless, some of the mushroom antifungal proteins have been shown to inhibit HIV-1 reverse transcriptase activity and tumor cell proliferation."/> <meta property="og:image" content="https://media.springernature.com/full/springer-static/cover-hires/journal/253"/> <meta name="format-detection" content="telephone=no"> <link rel="apple-touch-icon" sizes="180x180" href=/oscar-static/img/favicons/darwin/apple-touch-icon-92e819bf8a.png> <link rel="icon" type="image/png" sizes="192x192" href=/oscar-static/img/favicons/darwin/android-chrome-192x192-6f081ca7e5.png> <link rel="icon" type="image/png" sizes="32x32" href=/oscar-static/img/favicons/darwin/favicon-32x32-1435da3e82.png> <link rel="icon" type="image/png" sizes="16x16" href=/oscar-static/img/favicons/darwin/favicon-16x16-ed57f42bd2.png> <link rel="shortcut icon" data-test="shortcut-icon" href=/oscar-static/img/favicons/darwin/favicon-c6d59aafac.ico> <meta name="theme-color" content="#e6e6e6">   <link rel="stylesheet" media="print" 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This review focuses on antifungal proteins from plants and mushrooms, many of which are components of the human diet or have medicinal value. Plant antifungal proteins can be classified into different groups comprising chitinases and chitinase-like proteins, chitin-binding proteins, cyclophilin-like proteins, defensins and defensin-like proteins, deoxyribonucleases, embryo-abundant protein-like proteins, glucanases, lectins, lipid transfer proteins, peroxidases, protease inhibitors, ribonucleases, ribosome-inactivating proteins, storage 2S albumins, and thaumatin-like proteins. Some of the aforementioned antifungal proteins also exhibit mitogenic activity towards spleen cells, nitric oxide inducing activity toward macrophages, antiproliferative activity toward tumor cells, antibacterial activity, and inhibitory activity toward HIV-1 reverse transcriptase. In contrast to the large diversity of plant antifungal proteins, only a small number of mushroom antifungal proteins have been reported. Mushroom antifungal proteins are distinct from their plant counterparts in N-terminal sequence. Nevertheless, some of the mushroom antifungal proteins have been shown to inhibit HIV-1 reverse transcriptase activity and tumor cell proliferation.","datePublished":"2010-06-08T00:00:00Z","dateModified":"2010-06-08T00:00:00Z","pageStart":"1221","pageEnd":"1235","sameAs":"https://doi.org/10.1007/s00253-010-2690-4","keywords":["Antifungal","Medicinal","Plants","Mushrooms","Microbiology","Microbial Genetics and Genomics","Biotechnology"],"image":[],"isPartOf":{"name":"Applied Microbiology and Biotechnology","issn":["1432-0614","0175-7598"],"volumeNumber":"87","@type":["Periodical","PublicationVolume"]},"publisher":{"name":"Springer-Verlag","logo":{"url":"https://www.springernature.com/app-sn/public/images/logo-springernature.png","@type":"ImageObject"},"@type":"Organization"},"author":[{"name":"Jack H. 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Ye","affiliation":[{"name":"The Chinese University of Hong Kong","address":{"name":"The School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, New Territories, China","@type":"PostalAddress"},"@type":"Organization"}],"@type":"Person"},{"name":"H. X. Wang","affiliation":[{"name":"China Agricultural University","address":{"name":"State Key Laboratory of Agrobiotechnology, Department of Microbiology, China Agricultural University, Beijing, China","@type":"PostalAddress"},"@type":"Organization"}],"email":"hxwang@cau.edu.cn","@type":"Person"},{"name":"S. K. Lam","affiliation":[{"name":"The Chinese University of Hong Kong","address":{"name":"The School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, New Territories, China","@type":"PostalAddress"},"@type":"Organization"}],"@type":"Person"},{"name":"P. Lin","affiliation":[{"name":"The Chinese University of Hong Kong","address":{"name":"The School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, New Territories, China","@type":"PostalAddress"},"@type":"Organization"}],"@type":"Person"},{"name":"Y. S. Chan","affiliation":[{"name":"The Chinese University of Hong Kong","address":{"name":"The School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, New Territories, China","@type":"PostalAddress"},"@type":"Organization"}],"@type":"Person"},{"name":"Evandro F. Fang","affiliation":[{"name":"The Chinese University of Hong Kong","address":{"name":"The School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, New Territories, China","@type":"PostalAddress"},"@type":"Organization"}],"@type":"Person"},{"name":"Patrick H. K. 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</picture> <span class="app-article-masthead__journal-title">Applied Microbiology and Biotechnology</span> </a> <a href="https://link.springer.com/journal/253/aims-and-scope" class="app-article-masthead__submission-link" data-track="click_aims_and_scope" data-track-action="aims and scope" data-track-context="article page" data-track-label="link"> Aims and scope <svg width="16" height="16" focusable="false" role="img" aria-hidden="true" class="u-icon"><use xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="#icon-eds-i-arrow-right-medium"></use></svg> </a> <a href="https://www.editorialmanager.com/ambb/" class="app-article-masthead__submission-link" data-track="click_submit_manuscript" data-track-context="article masthead on springerlink article page" data-track-action="submit manuscript" data-track-label="link"> Submit manuscript <svg width="16" height="16" focusable="false" role="img" aria-hidden="true" class="u-icon"><use xmlns:xlink="http://www.w3.org/1999/xlink" 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Wong</a><sup class="u-js-hide"><a href="#Aff1">1</a></sup>, </li><li class="c-article-author-list__item"><a data-test="author-name" data-track="click" data-track-action="open author" data-track-label="link" href="#auth-T__B_-Ng-Aff1" data-author-popup="auth-T__B_-Ng-Aff1" data-author-search="Ng, T. B." data-corresp-id="c1">T. B. Ng<svg width="16" height="16" focusable="false" role="img" aria-hidden="true" class="u-icon"><use xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="#icon-eds-i-mail-medium"></use></svg></a><sup class="u-js-hide"><a href="#Aff1">1</a></sup>, </li><li class="c-article-author-list__item c-article-author-list__item--hide-small-screen"><a data-test="author-name" data-track="click" data-track-action="open author" data-track-label="link" href="#auth-Randy_C__F_-Cheung-Aff1" data-author-popup="auth-Randy_C__F_-Cheung-Aff1" data-author-search="Cheung, Randy C. F.">Randy C. F. 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Jiang</a><sup class="u-js-hide"><a href="#Aff6">6</a></sup> & </li><li class="c-article-author-list__show-more" aria-label="Show all 14 authors for this article" title="Show all 14 authors for this article">…</li><li class="c-article-author-list__item"><a data-test="author-name" data-track="click" data-track-action="open author" data-track-label="link" href="#auth-F_-Liu-Aff6" data-author-popup="auth-F_-Liu-Aff6" data-author-search="Liu, F.">F. 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This review focuses on antifungal proteins from plants and mushrooms, many of which are components of the human diet or have medicinal value. Plant antifungal proteins can be classified into different groups comprising chitinases and chitinase-like proteins, chitin-binding proteins, cyclophilin-like proteins, defensins and defensin-like proteins, deoxyribonucleases, embryo-abundant protein-like proteins, glucanases, lectins, lipid transfer proteins, peroxidases, protease inhibitors, ribonucleases, ribosome-inactivating proteins, storage 2S albumins, and thaumatin-like proteins. Some of the aforementioned antifungal proteins also exhibit mitogenic activity towards spleen cells, nitric oxide inducing activity toward macrophages, antiproliferative activity toward tumor cells, antibacterial activity, and inhibitory activity toward HIV-1 reverse transcriptase. In contrast to the large diversity of plant antifungal proteins, only a small number of mushroom antifungal proteins have been reported. Mushroom antifungal proteins are distinct from their plant counterparts in N-terminal sequence. 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Wong, T. B. Ng, Randy C. F. Cheung, X. J. Ye, S. K. Lam, P. Lin, Y. S. Chan & Evandro F. Fang</p></li><li id="Aff2"><p class="c-article-author-affiliation__address">State Key Laboratory of Agrobiotechnology, Department of Microbiology, China Agricultural University, Beijing, China</p><p class="c-article-author-affiliation__authors-list">H. X. Wang</p></li><li id="Aff3"><p class="c-article-author-affiliation__address">Department of Biochemistry, Faculty of Science, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China</p><p class="c-article-author-affiliation__authors-list">Patrick H. K. Ngai</p></li><li id="Aff4"><p class="c-article-author-affiliation__address">College of Medicine, Shenzhen University, Shenzhen, China</p><p class="c-article-author-affiliation__authors-list">L. X. Xia</p></li><li id="Aff5"><p class="c-article-author-affiliation__address">College of Biological Science and Technology, Fuzhou University, Fuzhou, China</p><p class="c-article-author-affiliation__authors-list">X. Y. Ye</p></li><li id="Aff6"><p class="c-article-author-affiliation__address">Department of Microbiology, College of Life Sciences, Nankai University, Tianjin, China</p><p class="c-article-author-affiliation__authors-list">Y. Jiang & F. Liu</p></li></ol><div class="u-js-hide u-hide-print" data-test="author-info"><span class="c-article__sub-heading">Authors</span><ol class="c-article-authors-search u-list-reset"><li id="auth-Jack_H_-Wong-Aff1"><span class="c-article-authors-search__title u-h3 js-search-name">Jack H. Wong</span><div class="c-article-authors-search__list"><div class="c-article-authors-search__item c-article-authors-search__list-item--left"><a href="/search?dc.creator=Jack%20H.%20Wong" class="c-article-button" data-track="click" data-track-action="author link - publication" data-track-label="link" rel="nofollow">View author publications</a></div><div class="c-article-authors-search__item c-article-authors-search__list-item--right"><p class="search-in-title-js c-article-authors-search__text">You can also search for this author in <span class="c-article-identifiers"><a class="c-article-identifiers__item" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&term=Jack%20H.%20Wong" data-track="click" data-track-action="author link - pubmed" data-track-label="link" rel="nofollow">PubMed</a><span class="u-hide"> </span><a class="c-article-identifiers__item" href="http://scholar.google.co.uk/scholar?as_q=&num=10&btnG=Search+Scholar&as_epq=&as_oq=&as_eq=&as_occt=any&as_sauthors=%22Jack%20H.%20Wong%22&as_publication=&as_ylo=&as_yhi=&as_allsubj=all&hl=en" data-track="click" data-track-action="author link - scholar" data-track-label="link" rel="nofollow">Google Scholar</a></span></p></div></div></li><li id="auth-T__B_-Ng-Aff1"><span class="c-article-authors-search__title u-h3 js-search-name">T. B. 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B. Ng</a>, <a id="corresp-c2" href="mailto:hxwang@cau.edu.cn">H. X. Wang</a> or <a id="corresp-c3" href="mailto:xialixin@126.com">L. X. Xia</a>.</p></div></div></section><section data-title="Rights and permissions"><div class="c-article-section" id="rightslink-section"><h2 class="c-article-section__title js-section-title js-c-reading-companion-sections-item" id="rightslink">Rights and permissions</h2><div class="c-article-section__content" id="rightslink-content"><p class="c-article-rights"><a data-track="click" data-track-action="view rights and permissions" data-track-label="link" href="https://s100.copyright.com/AppDispatchServlet?title=Proteins%20with%20antifungal%20properties%20and%20other%20medicinal%20applications%20from%20plants%20and%20mushrooms&author=Jack%20H.%20Wong%20et%20al&contentID=10.1007%2Fs00253-010-2690-4&copyright=Springer-Verlag&publication=0175-7598&publicationDate=2010-06-08&publisherName=SpringerNature&orderBeanReset=true">Reprints and permissions</a></p></div></div></section><section aria-labelledby="article-info" data-title="About this article"><div class="c-article-section" id="article-info-section"><h2 class="c-article-section__title js-section-title js-c-reading-companion-sections-item" id="article-info">About this article</h2><div class="c-article-section__content" id="article-info-content"><div class="c-bibliographic-information"><div class="c-bibliographic-information__column"><h3 class="c-article__sub-heading" id="citeas">Cite this article</h3><p class="c-bibliographic-information__citation">Wong, J.H., Ng, T.B., Cheung, R.C.F. <i>et al.</i> Proteins with antifungal properties and other medicinal applications from plants and mushrooms. <i>Appl Microbiol Biotechnol</i> <b>87</b>, 1221–1235 (2010). https://doi.org/10.1007/s00253-010-2690-4</p><p class="c-bibliographic-information__download-citation u-hide-print"><a data-test="citation-link" data-track="click" data-track-action="download article citation" data-track-label="link" data-track-external="" rel="nofollow" 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