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class="vector-pinnable-header-label">Tartalomjegyzék</h2> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-toc.pin">áthelyezés az oldalsávba</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-toc.unpin">elrejtés</button> </div> <ul class="vector-toc-contents" id="mw-panel-toc-list"> <li id="toc-mw-content-text" class="vector-toc-list-item vector-toc-level-1"> <a href="#" class="vector-toc-link"> <div class="vector-toc-text">Bevezető</div> </a> </li> <li id="toc-Szerkezete" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Szerkezete"> <div class="vector-toc-text"> <span class="vector-toc-numb">1</span> <span>Szerkezete</span> </div> </a> <ul id="toc-Szerkezete-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Feladata" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Feladata"> <div class="vector-toc-text"> <span class="vector-toc-numb">2</span> <span>Feladata</span> </div> </a> <button aria-controls="toc-Feladata-sublist" class="cdx-button cdx-button--weight-quiet cdx-button--icon-only vector-toc-toggle"> <span class="vector-icon mw-ui-icon-wikimedia-expand"></span> <span>A(z) Feladata alszakasz kinyitása/becsukása</span> </button> <ul id="toc-Feladata-sublist" class="vector-toc-list"> <li id="toc-Aktivin" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Aktivin"> <div class="vector-toc-text"> <span class="vector-toc-numb">2.1</span> <span>Aktivin</span> </div> </a> <ul id="toc-Aktivin-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Inhibin" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Inhibin"> <div class="vector-toc-text"> <span class="vector-toc-numb">2.2</span> <span>Inhibin</span> </div> </a> <ul id="toc-Inhibin-sublist" class="vector-toc-list"> <li id="toc-Nőkben" class="vector-toc-list-item vector-toc-level-3"> <a class="vector-toc-link" href="#Nőkben"> <div class="vector-toc-text"> <span class="vector-toc-numb">2.2.1</span> <span>Nőkben</span> </div> </a> <ul id="toc-Nőkben-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Férfiakban" class="vector-toc-list-item vector-toc-level-3"> <a class="vector-toc-link" href="#Férfiakban"> <div class="vector-toc-text"> <span class="vector-toc-numb">2.2.2</span> <span>Férfiakban</span> </div> </a> <ul id="toc-Férfiakban-sublist" class="vector-toc-list"> </ul> </li> </ul> </li> </ul> </li> <li id="toc-Klinikai_jelentősége" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Klinikai_jelentősége"> <div class="vector-toc-text"> <span class="vector-toc-numb">3</span> <span>Klinikai jelentősége</span> </div> </a> <button aria-controls="toc-Klinikai_jelentősége-sublist" class="cdx-button cdx-button--weight-quiet cdx-button--icon-only vector-toc-toggle"> <span class="vector-icon mw-ui-icon-wikimedia-expand"></span> <span>A(z) Klinikai jelentősége alszakasz kinyitása/becsukása</span> </button> <ul id="toc-Klinikai_jelentősége-sublist" class="vector-toc-list"> <li id="toc-Aktivin_2" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Aktivin_2"> <div class="vector-toc-text"> <span class="vector-toc-numb">3.1</span> <span>Aktivin</span> </div> </a> <ul id="toc-Aktivin_2-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Inhibin_2" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Inhibin_2"> <div class="vector-toc-text"> <span class="vector-toc-numb">3.2</span> <span>Inhibin</span> </div> </a> <ul id="toc-Inhibin_2-sublist" class="vector-toc-list"> </ul> </li> </ul> </li> <li id="toc-Jegyzetek" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Jegyzetek"> <div class="vector-toc-text"> <span class="vector-toc-numb">4</span> <span>Jegyzetek</span> </div> </a> <ul id="toc-Jegyzetek-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Fordítás" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Fordítás"> <div class="vector-toc-text"> <span class="vector-toc-numb">5</span> <span>Fordítás</span> </div> </a> <ul id="toc-Fordítás-sublist" class="vector-toc-list"> </ul> </li> </ul> </div> </div> </nav> </div> </div> <div class="mw-content-container"> <main id="content" class="mw-body"> <header class="mw-body-header vector-page-titlebar"> <nav aria-label="Tartalomjegyzék" class="vector-toc-landmark"> <div id="vector-page-titlebar-toc" class="vector-dropdown vector-page-titlebar-toc vector-button-flush-left" title="Tartalomjegyzék" > <input type="checkbox" id="vector-page-titlebar-toc-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-titlebar-toc" class="vector-dropdown-checkbox " aria-label="Tartalomjegyzék kinyitása/becsukása" > <label id="vector-page-titlebar-toc-label" for="vector-page-titlebar-toc-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-listBullet mw-ui-icon-wikimedia-listBullet"></span> <span class="vector-dropdown-label-text">Tartalomjegyzék kinyitása/becsukása</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-titlebar-toc-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <h1 id="firstHeading" class="firstHeading mw-first-heading"><span class="mw-page-title-main">Aktivin</span></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" > <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="Ugrás egy más nyelvű szócikkre. Elérhető 5 nyelven" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-5" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">5 nyelv</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/Activine" title="Activine – francia" lang="fr" hreflang="fr" data-title="Activine" data-language-autonym="Français" data-language-local-name="francia" class="interlanguage-link-target"><span>Français</span></a></li><li class="interlanguage-link interwiki-gl mw-list-item"><a href="https://gl.wikipedia.org/wiki/Activina" title="Activina – gallego" lang="gl" hreflang="gl" data-title="Activina" data-language-autonym="Galego" data-language-local-name="gallego" class="interlanguage-link-target"><span>Galego</span></a></li><li class="interlanguage-link interwiki-ja mw-list-item"><a href="https://ja.wikipedia.org/wiki/%E3%82%A2%E3%82%AF%E3%83%81%E3%83%93%E3%83%B3" title="アクチビン – japán" lang="ja" hreflang="ja" data-title="アクチビン" data-language-autonym="日本語" data-language-local-name="japán" class="interlanguage-link-target"><span>日本語</span></a></li><li class="interlanguage-link interwiki-pt mw-list-item"><a href="https://pt.wikipedia.org/wiki/Activina" title="Activina – portugál" lang="pt" hreflang="pt" data-title="Activina" data-language-autonym="Português" data-language-local-name="portugál" class="interlanguage-link-target"><span>Português</span></a></li><li class="interlanguage-link interwiki-ru mw-list-item"><a href="https://ru.wikipedia.org/wiki/%D0%90%D0%BA%D1%82%D0%B8%D0%B2%D0%B8%D0%BD" title="Активин – orosz" lang="ru" hreflang="ru" data-title="Активин" data-language-autonym="Русский" data-language-local-name="orosz" class="interlanguage-link-target"><span>Русский</span></a></li> </ul> <div class="after-portlet after-portlet-lang"><span class="wb-langlinks-edit wb-langlinks-link"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q22327407#sitelinks-wikipedia" title="Nyelvközi hivatkozások szerkesztése" class="wbc-editpage">Hivatkozások szerkesztése</a></span></div> </div> </div> </div> </header> <div class="vector-page-toolbar"> <div class="vector-page-toolbar-container"> <div id="left-navigation"> <nav aria-label="Névterek"> <div id="p-associated-pages" class="vector-menu vector-menu-tabs mw-portlet mw-portlet-associated-pages" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-nstab-main" class="selected vector-tab-noicon mw-list-item"><a href="/wiki/Aktivin" title="A lap megtekintése [c]" accesskey="c"><span>Szócikk</span></a></li><li id="ca-talk" class="new vector-tab-noicon mw-list-item"><a href="/w/index.php?title=Vita:Aktivin&action=edit&redlink=1" rel="discussion" class="new" title="Az oldal tartalmának megvitatása (a lap nem létezik) [t]" accesskey="t"><span>Vitalap</span></a></li> </ul> </div> </div> <div id="vector-variants-dropdown" class="vector-dropdown emptyPortlet" > <input type="checkbox" id="vector-variants-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-variants-dropdown" class="vector-dropdown-checkbox " aria-label="Nyelvvariáns váltása" > <label id="vector-variants-dropdown-label" for="vector-variants-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet" aria-hidden="true" ><span class="vector-dropdown-label-text">magyar</span> </label> <div class="vector-dropdown-content"> <div id="p-variants" class="vector-menu mw-portlet mw-portlet-variants emptyPortlet" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> </ul> </div> </div> </div> </div> </nav> </div> <div id="right-navigation" class="vector-collapsible"> <nav aria-label="Nézetek"> <div id="p-views" class="vector-menu vector-menu-tabs mw-portlet mw-portlet-views" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-view" class="selected vector-tab-noicon mw-list-item"><a href="/wiki/Aktivin"><span>Olvasás</span></a></li><li id="ca-edit" class="vector-tab-noicon mw-list-item"><a href="/w/index.php?title=Aktivin&action=edit" title="Az oldal forráskódjának szerkesztése [e]" accesskey="e"><span>Szerkesztés</span></a></li><li id="ca-history" class="vector-tab-noicon mw-list-item"><a href="/w/index.php?title=Aktivin&action=history" title="A lap korábbi változatai [h]" accesskey="h"><span>Laptörténet</span></a></li> </ul> </div> </div> </nav> <nav class="vector-page-tools-landmark" aria-label="Oldal eszközök"> <div 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data-pinned-container-id="vector-page-tools-pinned-container" data-unpinned-container-id="vector-page-tools-unpinned-container" > <div class="vector-pinnable-header-label">Eszközök</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-page-tools.pin">áthelyezés az oldalsávba</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-page-tools.unpin">elrejtés</button> </div> <div id="p-cactions" class="vector-menu mw-portlet mw-portlet-cactions emptyPortlet vector-has-collapsible-items" title="További lehetőségek" > <div class="vector-menu-heading"> Műveletek </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-more-view" class="selected vector-more-collapsible-item mw-list-item"><a href="/wiki/Aktivin"><span>Olvasás</span></a></li><li id="ca-more-edit" class="vector-more-collapsible-item mw-list-item"><a href="/w/index.php?title=Aktivin&action=edit" title="Az oldal forráskódjának szerkesztése [e]" accesskey="e"><span>Szerkesztés</span></a></li><li id="ca-more-history" class="vector-more-collapsible-item mw-list-item"><a href="/w/index.php?title=Aktivin&action=history"><span>Laptörténet</span></a></li> </ul> </div> </div> <div id="p-tb" class="vector-menu mw-portlet mw-portlet-tb" > <div class="vector-menu-heading"> Általános </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="t-whatlinkshere" class="mw-list-item"><a href="/wiki/Speci%C3%A1lis:Mi_hivatkozik_erre/Aktivin" title="Az erre a lapra hivatkozó más lapok listája [j]" accesskey="j"><span>Mi hivatkozik erre?</span></a></li><li id="t-recentchangeslinked" class="mw-list-item"><a href="/wiki/Speci%C3%A1lis:Kapcsol%C3%B3d%C3%B3_v%C3%A1ltoztat%C3%A1sok/Aktivin" rel="nofollow" title="Az erről a lapról hivatkozott lapok utolsó változtatásai [k]" accesskey="k"><span>Kapcsolódó változtatások</span></a></li><li id="t-permalink" class="mw-list-item"><a href="/w/index.php?title=Aktivin&oldid=27193594" title="Állandó hivatkozás ezen lap ezen változatához"><span>Hivatkozás erre a változatra</span></a></li><li id="t-info" class="mw-list-item"><a href="/w/index.php?title=Aktivin&action=info" title="További információk erről a lapról"><span>Lapinformációk</span></a></li><li id="t-cite" class="mw-list-item"><a href="/w/index.php?title=Speci%C3%A1lis:Hivatkoz%C3%A1s&page=Aktivin&id=27193594&wpFormIdentifier=titleform" title="Információk a lap idézésével kapcsolatban"><span>Hogyan hivatkozz erre a lapra?</span></a></li><li id="t-urlshortener" class="mw-list-item"><a href="/w/index.php?title=Speci%C3%A1lis:UrlShortener&url=https%3A%2F%2Fhu.wikipedia.org%2Fwiki%2FAktivin"><span>Rövidített URL készítése</span></a></li><li id="t-urlshortener-qrcode" class="mw-list-item"><a href="/w/index.php?title=Speci%C3%A1lis:QrCode&url=https%3A%2F%2Fhu.wikipedia.org%2Fwiki%2FAktivin"><span>QR-kód letöltése</span></a></li> </ul> </div> </div> <div id="p-coll-print_export" class="vector-menu mw-portlet mw-portlet-coll-print_export" > <div class="vector-menu-heading"> Nyomtatás/exportálás </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="coll-create_a_book" class="mw-list-item"><a href="/w/index.php?title=Speci%C3%A1lis:K%C3%B6nyv&bookcmd=book_creator&referer=Aktivin"><span>Könyv készítése</span></a></li><li id="coll-download-as-rl" class="mw-list-item"><a href="/w/index.php?title=Speci%C3%A1lis:DownloadAsPdf&page=Aktivin&action=show-download-screen"><span>Letöltés PDF-ként</span></a></li><li id="t-print" class="mw-list-item"><a href="/w/index.php?title=Aktivin&printable=yes" title="A lap nyomtatható változata [p]" accesskey="p"><span>Nyomtatható változat</span></a></li> </ul> </div> </div> <div id="p-wikibase-otherprojects" class="vector-menu mw-portlet mw-portlet-wikibase-otherprojects" > <div class="vector-menu-heading"> Társprojektek </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="t-wikibase" class="wb-otherproject-link wb-otherproject-wikibase-dataitem mw-list-item"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q22327407" title="Kapcsolt adattárelem [g]" accesskey="g"><span>Wikidata-adatlap</span></a></li> </ul> </div> </div> </div> </div> </div> </div> </nav> </div> </div> </div> <div class="vector-column-end"> <div class="vector-sticky-pinned-container"> <nav class="vector-page-tools-landmark" aria-label="Oldal eszközök"> <div id="vector-page-tools-pinned-container" class="vector-pinned-container"> </div> </nav> <nav class="vector-appearance-landmark" aria-label="Megjelenés"> <div id="vector-appearance-pinned-container" class="vector-pinned-container"> <div id="vector-appearance" class="vector-appearance vector-pinnable-element"> <div class="vector-pinnable-header vector-appearance-pinnable-header vector-pinnable-header-pinned" data-feature-name="appearance-pinned" data-pinnable-element-id="vector-appearance" data-pinned-container-id="vector-appearance-pinned-container" data-unpinned-container-id="vector-appearance-unpinned-container" > <div class="vector-pinnable-header-label">Megjelenés</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-appearance.pin">áthelyezés az oldalsávba</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-appearance.unpin">elrejtés</button> </div> </div> </div> </nav> </div> </div> <div id="bodyContent" class="vector-body" aria-labelledby="firstHeading" data-mw-ve-target-container> <div class="vector-body-before-content"> <div class="mw-indicators"> <div id="mw-indicator-indicator-fr-review-status" 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Az 1986-ban felfedezett<sup id="cite_ref-pmid3012369_1-0" class="reference"><a href="#cite_note-pmid3012369-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid3086749_2-0" class="reference"><a href="#cite_note-pmid3086749-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> aktivin fokozza a <a href="/wiki/Follikuluszstimul%C3%A1l%C3%B3_hormon" title="Follikuluszstimuláló hormon">follikuluszstimuláló hormon</a> (FSH) szintézisét és kiválasztását és részt vesz a <a href="/wiki/Menstru%C3%A1ci%C3%B3s_ciklus" title="Menstruációs ciklus">menstruációs ciklus</a> szabályozásában. A test más részeiben egyéb funkciói is vannak, például a sebgyógyulásban és a magzati fejlődés során.<sup id="cite_ref-pmid15451577_3-0" class="reference"><a href="#cite_note-pmid15451577-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup> Ezzel szemben az inhibin gátolja az FSH termelését.<sup id="cite_ref-4" class="reference"><a href="#cite_note-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup> Az inhibin létezését már 1916-ban is feltételezték, de csak a 70-es években mutatta ki az amerikai Neena Schwartz és Cornelia Channing.<sup id="cite_ref-5" class="reference"><a href="#cite_note-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup> </p><p>Az aktivin két egyforma vagy nagyon hasonló béta-alegységből áll. Az inhibin két alegysége közül az egyik szintén az aktivinével azonos béta; a másik viszont egy, csak kevéssé hasonlító alfa-alegység.<sup id="cite_ref-pmid3346366_6-0" class="reference"><a href="#cite_note-pmid3346366-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid15027884_7-0" class="reference"><a href="#cite_note-pmid15027884-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup> </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="Szerkezete">Szerkezete</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Aktivin&action=edit&section=1" title="Szakasz szerkesztése: Szerkezete"><span>szerkesztés</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Mind az aktivin, mind az inhibin két-két alegységből álló dimer <a href="/wiki/Feh%C3%A9rje" title="Fehérje">fehérjekomplex</a>, ahol az alegységeket egyetlen diszulfid-híd köti össze.<sup id="cite_ref-pmid3122219_8-0" class="reference"><a href="#cite_note-pmid3122219-8"><span class="cite-bracket">[</span>8<span class="cite-bracket">]</span></a></sup> Az összetevők két fehérjecsaládba, az alfa és béta családba tartoznak, amelyek között a szekvenciahasonlóság kb. 25%-os, míg a béta családon belül 65%-os az egyezés.<sup id="cite_ref-pmid8299934_9-0" class="reference"><a href="#cite_note-pmid8299934-9"><span class="cite-bracket">[</span>9<span class="cite-bracket">]</span></a></sup> Az aktivin két azonos vagy egymással rokon béta alegységből áll, míg az inhibin egy béta és egy alfa összetevőt tartalmaz. Az alegységek többféle kombinációban állhatnak össze: </p> <p class="mw-empty-elt"></p><table cellspacing="0" cellpadding="0" class="" style="background-color: transparent; color:inherit; width: auto"> <tbody><tr> <td width="" align="left" valign="top" style="padding-left:;"> <table class="wikitable" border="3" style="text-align:center"> <tbody><tr> <th rowspan="2" width="100">Csoport </th> <th rowspan="2" width="100">Hatás </th> <th rowspan="2" width="100">Komplex </th> <th colspan="3">Alegységek </th></tr> <tr> <th width="80">1 </th> <th width="80">2 </th></tr> <tr> <td rowspan="2">Inhibin </td> <td rowspan="2">gátolja az FSH-t </td> <td>Inhibin A </td> <td>α </td> <td>β<sub>A</sub> </td></tr> <tr> <td>Inhibin B </td> <td>α </td> <td>β<sub>B</sub> </td></tr> <tr> <td rowspan="3">Aktivin </td> <td rowspan="3">serkenti az FSH-t </td> <td>Aktivin A </td> <td>β<sub>A</sub> </td> <td>β<sub>A</sub> </td></tr> <tr> <td>Aktivin AB </td> <td>β<sub>A</sub> </td> <td>β<sub>B</sub> </td></tr> <tr> <td>Aktivin B </td> <td>β<sub>B</sub> </td> <td>β<sub>B</sub> </td></tr></tbody></table> <p class="mw-empty-elt"></p> </td> <td width="" align="left" valign="top" style="padding-left:;"> <figure class="mw-halign-right" typeof="mw:File/Thumb"><a href="/wiki/F%C3%A1jl:Activin_inhibin.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/5/52/Activin_inhibin.png/480px-Activin_inhibin.png" decoding="async" width="480" height="178" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/5/52/Activin_inhibin.png/720px-Activin_inhibin.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/5/52/Activin_inhibin.png/960px-Activin_inhibin.png 2x" data-file-width="1403" data-file-height="521" /></a><figcaption>Az inhibin és az aktivin sematikus szerkezete</figcaption></figure> </td></tr></tbody></table> <p>Emlősökben négy béta-alegység ismert (aktivin β<sub>A</sub>, β<sub>B</sub>, β<sub>C</sub> és β<sub>E</sub>), míg a <a href="/wiki/Xenopus" class="mw-redirect" title="Xenopus">karmosbékából</a> leírtak egy ötödik típust (β<sub>D</sub>) is.<sup id="cite_ref-pmid16973148_10-0" class="reference"><a href="#cite_note-pmid16973148-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid18350601_11-0" class="reference"><a href="#cite_note-pmid18350601-11"><span class="cite-bracket">[</span>11<span class="cite-bracket">]</span></a></sup> </p><p>A β<sub>C</sub> képtelen az alfa-alegységhez kötődni, így inhibinben nem található.<sup id="cite_ref-pmid11134153_12-0" class="reference"><a href="#cite_note-pmid11134153-12"><span class="cite-bracket">[</span>12<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Feladata">Feladata</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Aktivin&action=edit&section=2" title="Szakasz szerkesztése: Feladata"><span>szerkesztés</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="mw-heading mw-heading3"><h3 id="Aktivin">Aktivin</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Aktivin&action=edit&section=3" title="Szakasz szerkesztése: Aktivin"><span>szerkesztés</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Aktivin a <a href="/wiki/Nemi_szerv" class="mw-redirect" title="Nemi szerv">nemi szervekben</a>, az <a href="/wiki/Agyalapi_mirigy" title="Agyalapi mirigy">agyalapi mirigyben</a>, a <a href="/wiki/M%C3%A9hlep%C3%A9ny" title="Méhlepény">méhlepényben</a> és egyéb szervekben képződik: </p> <ul><li>a <a href="/wiki/Petef%C3%A9szek" title="Petefészek">petefészek</a> tüszőjében fokozza a follikuluszstimuláló hormon (FSH) kötődését. Erősíti a <a href="/wiki/Luteiniz%C3%A1l%C3%B3_hormon" title="Luteinizáló hormon">luteinizáló hormon</a> hatását a petefészekben és a <a href="/wiki/Here_(anat%C3%B3mia)" title="Here (anatómia)">herékben</a>, ezáltal közvetetten elősegíti a férfi nemi hormon szintézisét. Az aktivin férfiakban meggyorsítja a spermiumok termelődését.</li> <li>nagy mennyiségben termelődik a sérült bőrben. Ha egérben génsebészeti módszerrel megnövelik a génje kifejeződését, az állat fokozott sebgyógyulást mutat. Kimutatták, hogy dózisfüggő módon stimulálja a bőr <a href="/wiki/Keratinocita" title="Keratinocita">keratinocitáit</a> és <a href="/w/index.php?title=Sztr%C3%B3masejt&action=edit&redlink=1" class="new" title="Sztrómasejt (a lap nem létezik)">sztrómasejtjeit</a>.<sup id="cite_ref-pmid16127153_13-0" class="reference"><a href="#cite_note-pmid16127153-13"><span class="cite-bracket">[</span>13<span class="cite-bracket">]</span></a></sup></li> <li>az embrióban szabályozza a <a href="/wiki/Vese" title="Vese">vese</a>, a <a href="/wiki/T%C3%BCd%C5%91" title="Tüdő">tüdő</a> és a <a href="/wiki/Prosztata" title="Prosztata">prosztata</a> kialakulását. Az aktivin A kísérletes körülmények között fokozta a <a href="/wiki/Kollag%C3%A9n" title="Kollagén">kollagén</a> termelődést, ezért feltételezik, hogy aktiválja a <a href="/w/index.php?title=Fibroblaszt&action=edit&redlink=1" class="new" title="Fibroblaszt (a lap nem létezik)">fibroblasztokat</a>.</li> <li>aktivinhiány esetén az embrióban idegfejlődési zavarok lépnek fel.</li></ul> <div class="mw-heading mw-heading3"><h3 id="Inhibin">Inhibin</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Aktivin&action=edit&section=4" title="Szakasz szerkesztése: Inhibin"><span>szerkesztés</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Az inhibin nőkben és férfiakban egyaránt csökkenti az FSH termelődését. A <a href="/wiki/Hipotalamusz" title="Hipotalamusz">hipotalamusz</a> <a href="/wiki/Gonadotropinfelszabad%C3%ADt%C3%B3_hormon" title="Gonadotropinfelszabadító hormon">gonadotropinfelszabadító hormonjára</a> (amely az FSH-t szabályozza) nincs hatással.<sup id="cite_ref-pmid15618291_14-0" class="reference"><a href="#cite_note-pmid15618291-14"><span class="cite-bracket">[</span>14<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-15" class="reference"><a href="#cite_note-15"><span class="cite-bracket">[</span>15<span class="cite-bracket">]</span></a></sup> Működése a különböző nemekben eltér: </p> <div class="mw-heading mw-heading4"><h4 id="Nőkben"><span id="N.C5.91kben"></span>Nőkben</h4><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Aktivin&action=edit&section=5" title="Szakasz szerkesztése: Nőkben"><span>szerkesztés</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Inhibin a petefészekben, agyalapi mirigyben, méhlepényben, a <a href="/w/index.php?title=S%C3%A1rgatest&action=edit&redlink=1" class="new" title="Sárgatest (a lap nem létezik)">sárgatestben</a> és egyéb szervekben keletkezik. </p><p>Az FSH a petesejt tüszőinek <a href="/w/index.php?title=Granulosa_sejt&action=edit&redlink=1" class="new" title="Granulosa sejt (a lap nem létezik)">granulosa sejtjeiben</a> fokozza az inhibin termelését, amely viszont gátolja az FSH-t; vagyis egy <a href="/w/index.php?title=Negat%C3%ADv_visszacsatol%C3%A1s&action=edit&redlink=1" class="new" title="Negatív visszacsatolás (a lap nem létezik)">negatív visszacsatolással</a> szabályozza a hormon szintjét. </p><p>Az inhibin B szintje a tüsző fejlődésének elején-közepén, valamint az ovulációnál éri el csúcspontját. Az inhibin A koncentrációja a sárgatest-fázis közepén a legmagasabb. Az inhibin elválasztását a gonadotropinfelszabadító hormon csökkenti, az <a href="/w/index.php?title=Inzulinszer%C5%B1_n%C3%B6veked%C3%A9si_faktor_1&action=edit&redlink=1" class="new" title="Inzulinszerű növekedési faktor 1 (a lap nem létezik)">inzulinszerű növekedési faktor 1</a> pedig növeli. </p> <div class="mw-heading mw-heading4"><h4 id="Férfiakban"><span id="F.C3.A9rfiakban"></span>Férfiakban</h4><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Aktivin&action=edit&section=6" title="Szakasz szerkesztése: Férfiakban"><span>szerkesztés</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Férfiakban a herék <a href="/w/index.php?title=Sertoli-sejt&action=edit&redlink=1" class="new" title="Sertoli-sejt (a lap nem létezik)">Sertoli-sejtjeiben</a> képződik.<sup id="cite_ref-16" class="reference"><a href="#cite_note-16"><span class="cite-bracket">[</span>16<span class="cite-bracket">]</span></a></sup> Termelését a férfi nemi hormonok elősegítik. Az inhibin helyi szinten szabályozza a spermiumok képződését.<sup id="cite_ref-17" class="reference"><a href="#cite_note-17"><span class="cite-bracket">[</span>17<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Klinikai_jelentősége"><span id="Klinikai_jelent.C5.91s.C3.A9ge"></span>Klinikai jelentősége</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Aktivin&action=edit&section=7" title="Szakasz szerkesztése: Klinikai jelentősége"><span>szerkesztés</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="mw-heading mw-heading3"><h3 id="Aktivin_2">Aktivin</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Aktivin&action=edit&section=8" title="Szakasz szerkesztése: Aktivin"><span>szerkesztés</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>A túlsúlyos személyek <a href="/wiki/Zs%C3%ADrsz%C3%B6vet" title="Zsírszövet">zsírszöveteiben</a> magasabb az aktivin A szintje.<sup id="cite_ref-pmid20530742_18-0" class="reference"><a href="#cite_note-pmid20530742-18"><span class="cite-bracket">[</span>18<span class="cite-bracket">]</span></a></sup> A fehérjekomplex segíti a <a href="/wiki/Zs%C3%ADrsejt" class="mw-redirect" title="Zsírsejt">zsírsejtek</a> elődjeinek osztódását; ezzel szemben gátolja zsírsejtté való differenciálódásukat.<sup id="cite_ref-pmid20530742_18-1" class="reference"><a href="#cite_note-pmid20530742-18"><span class="cite-bracket">[</span>18<span class="cite-bracket">]</span></a></sup> Ezenkívül <a href="/wiki/Makrof%C3%A1g" title="Makrofág">makrofágokban</a> fokozza a gyulladásos folyamatot megindító <a href="/wiki/Citokin" title="Citokin">citokinek</a> képződését.<sup id="cite_ref-pmid20530742_18-2" class="reference"><a href="#cite_note-pmid20530742-18"><span class="cite-bracket">[</span>18<span class="cite-bracket">]</span></a></sup> </p><p>Az aktivin receptorában (ACVR1) történő egy bizonyos mutáció eredménye a <a href="/w/index.php?title=Fibrodysplasia_ossificans_progressiva&action=edit&redlink=1" class="new" title="Fibrodysplasia ossificans progressiva (a lap nem létezik)">fibrodysplasia ossificans progressiva</a>, egy rendkívül ritka, halálos kimenetelű betegség, ahol a kötőszövet fokozatosan elcsontosodik.<sup id="cite_ref-ACVR1_19-0" class="reference"><a href="#cite_note-ACVR1-19"><span class="cite-bracket">[</span>19<span class="cite-bracket">]</span></a></sup> A mutáció hatására a receptort normálisan gátló aktivin aktiválni fogja azt, ami hiperaktív csontnövekedést eredményez.<sup id="cite_ref-ACVR1_19-1" class="reference"><a href="#cite_note-ACVR1-19"><span class="cite-bracket">[</span>19<span class="cite-bracket">]</span></a></sup> Az aktivin elleni antitesttel állatmodellben más sikeresen meg tudták előzni a betegség előrehaladását.<sup id="cite_ref-Reuters_20-0" class="reference"><a href="#cite_note-Reuters-20"><span class="cite-bracket">[</span>20<span class="cite-bracket">]</span></a></sup> </p><p>Az ACVR1 más mutáció az agytumor egy fajtája, a <a href="/w/index.php?title=Gli%C3%B3ma&action=edit&redlink=1" class="new" title="Glióma (a lap nem létezik)">glióma</a> kialakulásához kapcsolhatóak.<sup id="cite_ref-21" class="reference"><a href="#cite_note-21"><span class="cite-bracket">[</span>21<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-urlCure_Brain_Cancer_-_News_-_Multiple_Breakthroughs_in_Childhood_Brain_Cancer_DIPG_22-0" class="reference"><a href="#cite_note-urlCure_Brain_Cancer_-_News_-_Multiple_Breakthroughs_in_Childhood_Brain_Cancer_DIPG-22"><span class="cite-bracket">[</span>22<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-pmid24705254_23-0" class="reference"><a href="#cite_note-pmid24705254-23"><span class="cite-bracket">[</span>23<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading3"><h3 id="Inhibin_2">Inhibin</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Aktivin&action=edit&section=9" title="Szakasz szerkesztése: Inhibin"><span>szerkesztés</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>A <a href="/wiki/Terhess%C3%A9g" title="Terhesség">terhesség</a> második harmadában végzett ún. <a href="/w/index.php?title=H%C3%A1rmas_teszt&action=edit&redlink=1" class="new" title="Hármas teszt (a lap nem létezik)">hármas tesztet</a> kiegészíthetik az inhibin A szintjének mérésével ("négyes teszt"). Magas koncentrációja <a href="/wiki/Down-szindr%C3%B3ma" title="Down-szindróma">Down-szindrómás</a> magzatra utal.<sup id="cite_ref-24" class="reference"><a href="#cite_note-24"><span class="cite-bracket">[</span>24<span class="cite-bracket">]</span></a></sup> A diagnosztikában a <a href="/wiki/Petef%C3%A9szekr%C3%A1k" title="Petefészekrák">petefészekrák</a> markereként is alkalmazható.<sup id="cite_ref-25" class="reference"><a href="#cite_note-25"><span class="cite-bracket">[</span>25<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-26" class="reference"><a href="#cite_note-26"><span class="cite-bracket">[</span>26<span class="cite-bracket">]</span></a></sup> </p><p>Férfiakban a csökkent inhibin B-szint az alacsony spermiumszám jele lehet. Normális esetben koncentrációja 140 pg/ml, ami terméketlen férfiakban 80 pg/ml körüli.<sup id="cite_ref-27" class="reference"><a href="#cite_note-27"><span class="cite-bracket">[</span>27<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Jegyzetek">Jegyzetek</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Aktivin&action=edit&section=10" title="Szakasz szerkesztése: Jegyzetek"><span>szerkesztés</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="ref-1col"><div style="-moz-column-count:2; -webkit-column-count:2; column-count:2; -webkit-column-gap: 3em; -moz-column-gap: 3em; column-gap: 3em;"><ol class="references"> <li id="cite_note-pmid3012369-1"><span class="mw-cite-backlink"><a href="#cite_ref-pmid3012369_1-0">↑</a></span> <span class="reference-text"><cite class="book citation" style="font-style:normal"> (1986) „Purification and characterization of an FSH releasing protein from porcine ovarian follicular fluid”. <i>Nature</i> <b>321</b> (6072), 776–9. o. <a href="/wiki/Digital_object_identifier" title="Digital object identifier">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1038/321776a0">10.1038/321776a0</a>. <a href="/wiki/PubMed#PubMed-azonosító" title="PubMed">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/3012369">3012369</a>.</cite><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Purification+and+characterization+of+an+FSH+releasing+protein+from+porcine+ovarian+follicular+fluid&rft.jtitle=Nature&rft.date=1986&rft.volume=321&rft.issue=6072&rft.pages=776%E2%80%939&rft_id=info:pmid/3012369&rft_id=info:doi/10.1038%2F321776a0"><span style="display:none"> </span></span></span> </li> <li id="cite_note-pmid3086749-2"><span class="mw-cite-backlink"><a href="#cite_ref-pmid3086749_2-0">↑</a></span> <span class="reference-text"><cite class="book citation" style="font-style:normal"> (1986) „Pituitary FSH is released by a heterodimer of the beta-subunits from the two forms of inhibin”. <i>Nature</i> <b>321</b> (6072), 779–82. o. <a href="/wiki/Digital_object_identifier" title="Digital object identifier">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1038/321779a0">10.1038/321779a0</a>. <a href="/wiki/PubMed#PubMed-azonosító" title="PubMed">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/3086749">3086749</a>.</cite><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Pituitary+FSH+is+released+by+a+heterodimer+of+the+beta-subunits+from+the+two+forms+of+inhibin&rft.jtitle=Nature&rft.date=1986&rft.volume=321&rft.issue=6072&rft.pages=779%E2%80%9382&rft_id=info:pmid/3086749&rft_id=info:doi/10.1038%2F321779a0"><span style="display:none"> </span></span></span> </li> <li id="cite_note-pmid15451577-3"><span class="mw-cite-backlink"><a href="#cite_ref-pmid15451577_3-0">↑</a></span> <span class="reference-text"><cite class="book citation" style="font-style:normal"> (2004. október 1.) „Activin: an important regulator of wound repair, fibrosis, and neuroprotection”. <i>Molecular and Cellular Endocrinology</i> <b>225</b> (1-2), 127–32. o. <a href="/wiki/Digital_object_identifier" title="Digital object identifier">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1016/j.mce.2004.07.011">10.1016/j.mce.2004.07.011</a>. <a href="/wiki/PubMed#PubMed-azonosító" title="PubMed">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/15451577">15451577</a>.</cite><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Activin%3A+an+important+regulator+of+wound+repair%2C+fibrosis%2C+and+neuroprotection&rft.jtitle=Molecular+and+Cellular+Endocrinology&rft.date=Oct+2004&rft.volume=225&rft.issue=1-2&rft.pages=127%E2%80%9332&rft_id=info:pmid/15451577&rft_id=info:doi/10.1016%2Fj.mce.2004.07.011"><span style="display:none"> </span></span></span> </li> <li id="cite_note-4"><span class="mw-cite-backlink"><a href="#cite_ref-4">↑</a></span> <span class="reference-text"><cite class="book citation" style="font-style:normal"> (2003. március 1.) „<a rel="nofollow" class="external text" href="https://archive.org/details/sim_human-reproduction_2003-03_18_3/page/495">Do cycle disturbances explain the age-related decline of female fertility? Cycle characteristics of women aged over 40 years compared with a reference population of young women</a>”. <i>Human Reproduction</i> <b>18</b> (3), 495–501. o. <a href="/wiki/Digital_object_identifier" title="Digital object identifier">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1093/humrep/deg138">10.1093/humrep/deg138</a>. <a href="/wiki/PubMed#PubMed-azonosító" title="PubMed">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/12615813">12615813</a>.</cite><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Do+cycle+disturbances+explain+the+age-related+decline+of+female+fertility%3F+Cycle+characteristics+of+women+aged+over+40+years+compared+with+a+reference+population+of+young+women&rft.jtitle=Human+Reproduction&rft.date=Mar+2003&rft.volume=18&rft.issue=3&rft.pages=495%E2%80%93501&rft_id=info:pmid/12615813&rft_id=info:doi/10.1093%2Fhumrep%2Fdeg138&rft_id=https%3A%2F%2Farchive.org%2Fdetails%2Fsim_human-reproduction_2003-03_18_3%2Fpage%2F495"><span style="display:none"> </span></span></span> </li> <li id="cite_note-5"><span class="mw-cite-backlink"><a href="#cite_ref-5">↑</a></span> <span class="reference-text"><cite class="book citation" style="font-style:normal"> (2014. október 1.) „Inhibin at 90: from discovery to clinical application, a historical review”. <i>Endocrine Reviews</i> <b>35</b> (5), 747–94. o. <a href="/wiki/Digital_object_identifier" title="Digital object identifier">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1210/er.2014-1003">10.1210/er.2014-1003</a>. <a href="/wiki/PubMed#PubMed-azonosító" title="PubMed">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/25051334">25051334</a>.</cite><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Inhibin+at+90%3A+from+discovery+to+clinical+application%2C+a+historical+review&rft.jtitle=Endocrine+Reviews&rft.date=Oct+2014&rft.volume=35&rft.issue=5&rft.pages=747%E2%80%9394&rft_id=info:pmid/25051334&rft_id=info:doi/10.1210%2Fer.2014-1003"><span style="display:none"> </span></span></span> </li> <li id="cite_note-pmid3346366-6"><span class="mw-cite-backlink"><a href="#cite_ref-pmid3346366_6-0">↑</a></span> <span class="reference-text"><cite class="book citation" style="font-style:normal"> (1988. április 1.) „Inhibin: definition and nomenclature, including related substances”. <i>The Journal of Clinical Endocrinology and Metabolism</i> <b>66</b> (4), 885–6. o. <a href="/wiki/PubMed#PubMed-azonosító" title="PubMed">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/3346366">3346366</a>.</cite><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Inhibin%3A+definition+and+nomenclature%2C+including+related+substances&rft.jtitle=The+Journal+of+Clinical+Endocrinology+and+Metabolism&rft.date=Apr+1988&rft.volume=66&rft.issue=4&rft.pages=885%E2%80%936&rft_id=info:pmid/3346366"><span style="display:none"> </span></span></span> </li> <li id="cite_note-pmid15027884-7"><span class="mw-cite-backlink"><a href="#cite_ref-pmid15027884_7-0">↑</a></span> <span class="reference-text"><cite class="book citation" style="font-style:normal"> (2004. március 1.) „Inhibin/activin and ovarian cancer”. <i>Endocrine-Related Cancer</i> <b>11</b> (1), 35–49. o, Kiadó: Bioscientifica. <a href="/wiki/Digital_object_identifier" title="Digital object identifier">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1677/erc.0.0110035">10.1677/erc.0.0110035</a>. <a href="/wiki/PubMed#PubMed-azonosító" title="PubMed">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/15027884">15027884</a>.</cite><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Inhibin%2Factivin+and+ovarian+cancer&rft.jtitle=Endocrine-Related+Cancer&rft.date=Mar+2004&rft.volume=11&rft.issue=1&rft.pages=35%E2%80%9349&rft_id=info:pmid/15027884&rft_id=info:doi/10.1677%2Ferc.0.0110035"><span style="display:none"> </span></span></span> </li> <li id="cite_note-pmid3122219-8"><span class="mw-cite-backlink"><a href="#cite_ref-pmid3122219_8-0">↑</a></span> <span class="reference-text"><cite class="book citation" style="font-style:normal"> (1987. december 1.) „Inhibins and activins: chemical properties and biological activity”. <i>Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine</i> <b>186</b> (3), 253–64. o. <a href="/wiki/Digital_object_identifier" title="Digital object identifier">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.3181/00379727-186-42611a">10.3181/00379727-186-42611a</a>. <a href="/wiki/PubMed#PubMed-azonosító" title="PubMed">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/3122219">3122219</a>.</cite><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Inhibins+and+activins%3A+chemical+properties+and+biological+activity&rft.jtitle=Proceedings+of+the+Society+for+Experimental+Biology+and+Medicine.+Society+for+Experimental+Biology+and+Medicine&rft.date=Dec+1987&rft.volume=186&rft.issue=3&rft.pages=253%E2%80%9364&rft_id=info:pmid/3122219&rft_id=info:doi/10.3181%2F00379727-186-42611a"><span style="display:none"> </span></span></span> </li> <li id="cite_note-pmid8299934-9"><span class="mw-cite-backlink"><a href="#cite_ref-pmid8299934_9-0">↑</a></span> <span class="reference-text"><cite class="book citation" style="font-style:normal"> (1994. január 1.) „<a rel="nofollow" class="external text" href="https://archive.org/details/sim_genes-development_1994-01_8_2/page/133">The TGF-beta superfamily: new members, new receptors, and new genetic tests of function in different organisms</a>”. <i>Genes & Development</i> <b>8</b> (2), 133–46. o. <a href="/wiki/Digital_object_identifier" title="Digital object identifier">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1101/gad.8.2.133">10.1101/gad.8.2.133</a>. <a href="/wiki/PubMed#PubMed-azonosító" title="PubMed">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/8299934">8299934</a>.</cite><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=The+TGF-beta+superfamily%3A+new+members%2C+new+receptors%2C+and+new+genetic+tests+of+function+in+different+organisms&rft.jtitle=Genes+%26+Development&rft.date=Jan+1994&rft.volume=8&rft.issue=2&rft.pages=133%E2%80%9346&rft_id=info:pmid/8299934&rft_id=info:doi/10.1101%2Fgad.8.2.133&rft_id=https%3A%2F%2Farchive.org%2Fdetails%2Fsim_genes-development_1994-01_8_2%2Fpage%2F133"><span style="display:none"> </span></span></span> </li> <li id="cite_note-pmid16973148-10"><span class="mw-cite-backlink"><a href="#cite_ref-pmid16973148_10-0">↑</a></span> <span class="reference-text"><cite class="book citation" style="font-style:normal"> (2006. november 1.) „The role of activin in neuropeptide induction and pain sensation”. <i>Developmental Biology</i> <b>299</b> (2), 303–9. o. <a href="/wiki/Digital_object_identifier" title="Digital object identifier">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1016/j.ydbio.2006.08.026">10.1016/j.ydbio.2006.08.026</a>. <a href="/wiki/PubMed#PubMed-azonosító" title="PubMed">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/16973148">16973148</a>.</cite><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=The+role+of+activin+in+neuropeptide+induction+and+pain+sensation&rft.jtitle=Developmental+Biology&rft.date=Nov+2006&rft.volume=299&rft.issue=2&rft.pages=303%E2%80%939&rft_id=info:pmid/16973148&rft_id=info:doi/10.1016%2Fj.ydbio.2006.08.026"><span style="display:none"> </span></span></span> </li> <li id="cite_note-pmid18350601-11"><span class="mw-cite-backlink"><a href="#cite_ref-pmid18350601_11-0">↑</a></span> <span class="reference-text"><cite class="book citation" style="font-style:normal"> (2008. március 1.) „<a rel="nofollow" class="external text" href="https://web.archive.org/web/20090422225137/http://www.wjgnet.com/1007-9327/14/1699.asp">Activins and activin antagonists in hepatocellular carcinoma</a>”. <i>World Journal of Gastroenterology</i> <b>14</b> (11), 1699–709. o. [2009. április 22-i dátummal az <a rel="nofollow" class="external text" href="http://www.wjgnet.com/1007-9327/14/1699.asp">eredetiből</a> archiválva]. <a href="/wiki/Digital_object_identifier" title="Digital object identifier">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.3748/wjg.14.1699">10.3748/wjg.14.1699</a>. <a href="/wiki/PubMed#PubMed-azonosító" title="PubMed">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/18350601">18350601</a>. <a href="/wiki/PubMed_Central" title="PubMed Central">PMC</a> <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2695910/">2695910</a>. (Hozzáférés: 2009. április 18.)</cite><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Activins+and+activin+antagonists+in+hepatocellular+carcinoma&rft.jtitle=World+Journal+of+Gastroenterology&rft.date=Mar+2008&rft.volume=14&rft.issue=11&rft.pages=1699%E2%80%93709&rft_id=info:pmid/18350601&rft_id=info:doi/10.3748%2Fwjg.14.1699&rft_id=http%3A%2F%2Fwww.wjgnet.com%2F1007-9327%2F14%2F1699.asp"><span style="display:none"> </span></span></span> </li> <li id="cite_note-pmid11134153-12"><span class="mw-cite-backlink"><a href="#cite_ref-pmid11134153_12-0">↑</a></span> <span class="reference-text"><cite class="book citation" style="font-style:normal"> (2000. december 1.) „Localization of activin beta(A)-, beta(B)-, and beta(C)-subunits in humanprostate and evidence for formation of new activin heterodimers of beta(C)-subunit”. <i>The Journal of Clinical Endocrinology and Metabolism</i> <b>85</b> (12), 4851–8. o. <a href="/wiki/Digital_object_identifier" title="Digital object identifier">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1210/jc.85.12.4851">10.1210/jc.85.12.4851</a>. <a href="/wiki/PubMed#PubMed-azonosító" title="PubMed">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/11134153">11134153</a>.</cite><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Localization+of+activin+beta%28A%29-%2C+beta%28B%29-%2C+and+beta%28C%29-subunits+in+humanprostate+and+evidence+for+formation+of+new+activin+heterodimers+of+beta%28C%29-subunit&rft.jtitle=The+Journal+of+Clinical+Endocrinology+and+Metabolism&rft.date=Dec+2000&rft.volume=85&rft.issue=12&rft.pages=4851%E2%80%938&rft_id=info:pmid/11134153&rft_id=info:doi/10.1210%2Fjc.85.12.4851"><span style="display:none"> </span></span></span> </li> <li id="cite_note-pmid16127153-13"><span class="mw-cite-backlink"><a href="#cite_ref-pmid16127153_13-0">↑</a></span> <span class="reference-text"><cite class="book citation" style="font-style:normal"> (2005. szeptember 1.) „<a rel="nofollow" class="external text" href="http://ajp.amjpathol.org/cgi/pmidlookup?view=long&pmid=16127153">Activin controls skin morphogenesis and wound repair predominantly via stromal cells and in a concentration-dependent manner via keratinocytes</a>”. <i>The American Journal of Pathology</i> <b>167</b> (3), 733–47. o. <a href="/wiki/Digital_object_identifier" title="Digital object identifier">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1016/S0002-9440(10)62047-0">10.1016/S0002-9440(10)62047-0</a>. <a href="/wiki/PubMed#PubMed-azonosító" title="PubMed">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/16127153">16127153</a>. <a href="/wiki/PubMed_Central" title="PubMed Central">PMC</a> <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1698729/">1698729</a>.</cite><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Activin+controls+skin+morphogenesis+and+wound+repair+predominantly+via+stromal+cells+and+in+a+concentration-dependent+manner+via+keratinocytes&rft.jtitle=The+American+Journal+of+Pathology&rft.date=Sep+2005&rft.volume=167&rft.issue=3&rft.pages=733%E2%80%9347&rft_id=info:pmid/16127153&rft_id=info:doi/10.1016%2FS0002-9440%2810%2962047-0&rft_id=http%3A%2F%2Fajp.amjpathol.org%2Fcgi%2Fpmidlookup%3Fview%3Dlong%26pmid%3D16127153"><span style="display:none"> </span></span><sup class="noprint Inline-Template"><span style="white-space: nowrap;">[<i><a rel="nofollow" class="external text" href="https://web.archive.org/web/*/http://ajp.amjpathol.org/cgi/pmidlookup?view=long&pmid=16127153"><span title="  2018-07">halott link</span></a></i>]</span></sup></span> </li> <li id="cite_note-pmid15618291-14"><span class="mw-cite-backlink"><a href="#cite_ref-pmid15618291_14-0">↑</a></span> <span class="reference-text"><cite class="book citation" style="font-style:normal"> (2005) „Inhibins in female and male reproductive physiology: role in gametogenesis, conception, implantation and early pregnancy”. <i>Human Reproduction Update</i> <b>11</b> (2), 123–35. o. <a href="/wiki/Digital_object_identifier" title="Digital object identifier">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1093/humupd/dmh057">10.1093/humupd/dmh057</a>. <a href="/wiki/PubMed#PubMed-azonosító" title="PubMed">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/15618291">15618291</a>.</cite><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Inhibins+in+female+and+male+reproductive+physiology%3A+role+in+gametogenesis%2C+conception%2C+implantation+and+early+pregnancy&rft.jtitle=Human+Reproduction+Update&rft.date=2005&rft.volume=11&rft.issue=2&rft.pages=123%E2%80%9335&rft_id=info:pmid/15618291&rft_id=info:doi/10.1093%2Fhumupd%2Fdmh057"><span style="display:none"> </span></span></span> </li> <li id="cite_note-15"><span class="mw-cite-backlink"><a href="#cite_ref-15">↑</a></span> <span class="reference-text"><cite class="book citation" style="font-style:normal"> <i><a rel="nofollow" class="external text" href="https://archive.org/details/firstaidforusmle2012leta">First Aid for the USMLE Step 1</a></i>. McGraw Hill, <a rel="nofollow" class="external text" href="https://archive.org/details/firstaidforusmle2012leta/page/n557">534</a>. o. (2012). <a href="/wiki/Speci%C3%A1lis:K%C3%B6nyvforr%C3%A1sok/978-0-07-177636-3" title="Speciális:Könyvforrások/978-0-07-177636-3">ISBN 978-0-07-177636-3</a></cite><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=book&rft.btitle=First+Aid+for+the+USMLE+Step+1&rft.date=2012&rft.pub=McGraw+Hill&rft.isbn=978-0-07-177636-3&rft_id=https%3A%2F%2Farchive.org%2Fdetails%2Ffirstaidforusmle2012leta"><span style="display: none;"> </span></span></span> </li> <li id="cite_note-16"><span class="mw-cite-backlink"><a href="#cite_ref-16">↑</a></span> <span class="reference-text"><cite class="book citation" style="font-style:normal"> (1989. október 1.) „<a rel="nofollow" class="external text" href="https://archive.org/details/sim_molecular-and-cellular-endocrinology_1989-10_66_2/page/239">Stimulation of Sertoli cell inhibin secretion by the testicular paracrine factor PModS</a>”. <i>Molecular and Cellular Endocrinology</i> <b>66</b> (2), 239–49. o. <a href="/wiki/Digital_object_identifier" title="Digital object identifier">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1016/0303-7207(89)90036-1">10.1016/0303-7207(89)90036-1</a>. <a href="/wiki/PubMed#PubMed-azonosító" title="PubMed">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/2515083">2515083</a>.</cite><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Stimulation+of+Sertoli+cell+inhibin+secretion+by+the+testicular+paracrine+factor+PModS&rft.jtitle=Molecular+and+Cellular+Endocrinology&rft.date=Oct+1989&rft.volume=66&rft.issue=2&rft.pages=239%E2%80%9349&rft_id=info:pmid/2515083&rft_id=info:doi/10.1016%2F0303-7207%2889%2990036-1&rft_id=https%3A%2F%2Farchive.org%2Fdetails%2Fsim_molecular-and-cellular-endocrinology_1989-10_66_2%2Fpage%2F239"><span style="display:none"> </span></span></span> </li> <li id="cite_note-17"><span class="mw-cite-backlink"><a href="#cite_ref-17">↑</a></span> <span class="reference-text"><cite class="book citation" style="font-style:normal"> (2001. november 1.) „Inhibin B in male reproduction: pathophysiology and clinical relevance”. <i>European Journal of Endocrinology / European Federation of Endocrine Societies</i> <b>145</b> (5), 561–71. o. <a href="/wiki/Digital_object_identifier" title="Digital object identifier">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1530/eje.0.1450561">10.1530/eje.0.1450561</a>. <a href="/wiki/PubMed#PubMed-azonosító" title="PubMed">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/11720872">11720872</a>.</cite><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Inhibin+B+in+male+reproduction%3A+pathophysiology+and+clinical+relevance&rft.jtitle=European+Journal+of+Endocrinology+%2F+European+Federation+of+Endocrine+Societies&rft.date=Nov+2001&rft.volume=145&rft.issue=5&rft.pages=561%E2%80%9371&rft_id=info:pmid/11720872&rft_id=info:doi/10.1530%2Feje.0.1450561"><span style="display:none"> </span></span></span> </li> <li id="cite_note-pmid20530742-18"><span class="mw-cite-backlink">↑ <a href="#cite_ref-pmid20530742_18-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-pmid20530742_18-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-pmid20530742_18-2"><sup><i><b>c</b></i></sup></a></span> <span class="reference-text"><cite class="book citation" style="font-style:normal"> (2010) „<a rel="nofollow" class="external text" href="http://diabetes.diabetesjournals.org/content/59/10/2513.long">Activin a plays a critical role in proliferation and differentiation of human adipose progenitors</a>”. <i>Diabetes</i> <b>59</b> (10), 2513-2521. o. <a href="/wiki/Digital_object_identifier" title="Digital object identifier">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.2337/db10-0013">10.2337/db10-0013</a>. <a href="/wiki/PubMed_Central" title="PubMed Central">PMC</a> <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279533/">3279533</a>.</cite><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Activin+a+plays+a+critical+role+in+proliferation+and+differentiation+of+human+adipose+progenitors&rft.jtitle=Diabetes&rft.date=2010&rft.volume=59&rft.issue=10&rft.pages=2513-2521&rft_id=info:doi/10.2337%2Fdb10-0013&rft_id=http%3A%2F%2Fdiabetes.diabetesjournals.org%2Fcontent%2F59%2F10%2F2513.long"><span style="display:none"> </span></span></span> </li> <li id="cite_note-ACVR1-19"><span class="mw-cite-backlink">↑ <a href="#cite_ref-ACVR1_19-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-ACVR1_19-1"><sup><i><b>b</b></i></sup></a></span> <span class="reference-text"><cite class="book citation" style="font-style:normal"> (2006. május 1.) „<a rel="nofollow" class="external text" href="http://www.nature.com/ng/journal/v38/n5/abs/ng1783.html">A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva</a>”. <i>Nature Genetics</i> <b>38</b> (5), 525–527. o. <a href="/wiki/Digital_object_identifier" title="Digital object identifier">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1038/ng1783">10.1038/ng1783</a>. <a href="/wiki/PubMed#PubMed-azonosító" title="PubMed">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/16642017">16642017</a>.</cite><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=A+recurrent+mutation+in+the+BMP+type+I+receptor+ACVR1+causes+inherited+and+sporadic+fibrodysplasia+ossificans+progressiva&rft.jtitle=Nature+Genetics&rft.date=May+2006&rft.volume=38&rft.issue=5&rft.pages=525%E2%80%93527&rft_id=info:pmid/16642017&rft_id=info:doi/10.1038%2Fng1783&rft_id=http%3A%2F%2Fwww.nature.com%2Fng%2Fjournal%2Fv38%2Fn5%2Fabs%2Fng1783.html"><span style="display:none"> </span></span></span> </li> <li id="cite_note-Reuters-20"><span class="mw-cite-backlink"><a href="#cite_ref-Reuters_20-0">↑</a></span> <span class="reference-text"><span class="citation">Julie Steenhuysen: <a rel="nofollow" class="external text" href="http://mobile.reuters.com/article/idUSKCN0R222Z20150902"><i>Regeneron scientists discover key to excess bone growth in rare disease</i></a>. Reuters, 2015. szeptember 2.</span></span> </li> <li id="cite_note-21"><span class="mw-cite-backlink"><a href="#cite_ref-21">↑</a></span> <span class="reference-text"><cite class="book citation" style="font-style:normal"> (2014. május 1.) „Recurrent activating ACVR1 mutations in diffuse intrinsic pontine glioma”. <i>Nature Genetics</i> <b>46</b> (5), 457–61. o. <a href="/wiki/Digital_object_identifier" title="Digital object identifier">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1038/ng.2925">10.1038/ng.2925</a>. <a href="/wiki/PubMed#PubMed-azonosító" title="PubMed">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/24705252">24705252</a>. <a href="/wiki/PubMed_Central" title="PubMed Central">PMC</a> <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018681/">4018681</a>.</cite><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Recurrent+activating+ACVR1+mutations+in+diffuse+intrinsic+pontine+glioma&rft.jtitle=Nature+Genetics&rft.date=May+2014&rft.volume=46&rft.issue=5&rft.pages=457%E2%80%9361&rft_id=info:pmid/24705252&rft_id=info:doi/10.1038%2Fng.2925"><span style="display:none"> </span></span></span> </li> <li id="cite_note-urlCure_Brain_Cancer_-_News_-_Multiple_Breakthroughs_in_Childhood_Brain_Cancer_DIPG-22"><span class="mw-cite-backlink"><a href="#cite_ref-urlCure_Brain_Cancer_-_News_-_Multiple_Breakthroughs_in_Childhood_Brain_Cancer_DIPG_22-0">↑</a></span> <span class="reference-text"><span class="citation"><a rel="nofollow" class="external text" href="https://web.archive.org/web/20200812124610/https://www.curebraincancer.org.au/news/1044/multiple-breakthroughs-in-childhood-brain-cancer"><i>Cure Brain Cancer - News - Multiple Breakthroughs in Childhood Brain Cancer DIPG</i></a>. Cure Brain Cancer Foundation. [2020. augusztus 12-i dátummal az <a rel="nofollow" class="external text" href="http://www.curebraincancer.org.au/news/1044/multiple-breakthroughs-in-childhood-brain-cancer">eredetiből</a> archiválva]. (Hozzáférés: 2017. január 24.)</span></span> </li> <li id="cite_note-pmid24705254-23"><span class="mw-cite-backlink"><a href="#cite_ref-pmid24705254_23-0">↑</a></span> <span class="reference-text"><cite class="book citation" style="font-style:normal"> (2014. május 1.) „Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations”. <i>Nature Genetics</i> <b>46</b> (5), 451–6. o. <a href="/wiki/Digital_object_identifier" title="Digital object identifier">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1038/ng.2936">10.1038/ng.2936</a>. <a href="/wiki/PubMed#PubMed-azonosító" title="PubMed">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/24705254">24705254</a>. <a href="/wiki/PubMed_Central" title="PubMed Central">PMC</a> <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997489/">3997489</a>.</cite><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Genomic+analysis+of+diffuse+intrinsic+pontine+gliomas+identifies+three+molecular+subgroups+and+recurrent+activating+ACVR1+mutations&rft.jtitle=Nature+Genetics&rft.date=May+2014&rft.volume=46&rft.issue=5&rft.pages=451%E2%80%936&rft_id=info:pmid/24705254&rft_id=info:doi/10.1038%2Fng.2936"><span style="display:none"> </span></span></span> </li> <li id="cite_note-24"><span class="mw-cite-backlink"><a href="#cite_ref-24">↑</a></span> <span class="reference-text"><cite class="book citation" style="font-style:normal"> (1996. május 1.) „<a rel="nofollow" class="external text" href="https://web.archive.org/web/20080108123039/http://content.nejm.org/cgi/content/short/334/19/1231">Dimeric inhibin A as a marker for Down's syndrome in early pregnancy</a>”. <i>The New England Journal of Medicine</i> <b>334</b> (19), 1231–6. o. [2008. január 8-i dátummal az <a rel="nofollow" class="external text" href="http://content.nejm.org/cgi/content/short/334/19/1231">eredetiből</a> archiválva]. <a href="/wiki/Digital_object_identifier" title="Digital object identifier">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1056/NEJM199605093341904">10.1056/NEJM199605093341904</a>. <a href="/wiki/PubMed#PubMed-azonosító" title="PubMed">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/8606718">8606718</a>. (Hozzáférés: 2017. január 24.)</cite><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Dimeric+inhibin+A+as+a+marker+for+Down%27s+syndrome+in+early+pregnancy&rft.jtitle=The+New+England+Journal+of+Medicine&rft.date=May+1996&rft.volume=334&rft.issue=19&rft.pages=1231%E2%80%936&rft_id=info:pmid/8606718&rft_id=info:doi/10.1056%2FNEJM199605093341904&rft_id=http%3A%2F%2Fcontent.nejm.org%2Fcgi%2Fcontent%2Fshort%2F334%2F19%2F1231"><span style="display:none"> </span></span></span> </li> <li id="cite_note-25"><span class="mw-cite-backlink"><a href="#cite_ref-25">↑</a></span> <span class="reference-text"><cite class="book citation" style="font-style:normal"> (2007. április 1.) „Inhibin as a diagnostic marker for ovarian cancer”. <i>Cancer Letters</i> <b>249</b> (1), 14–7. o. <a href="/wiki/Digital_object_identifier" title="Digital object identifier">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1016/j.canlet.2006.12.017">10.1016/j.canlet.2006.12.017</a>. <a href="/wiki/PubMed#PubMed-azonosító" title="PubMed">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/17320281">17320281</a>.</cite><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Inhibin+as+a+diagnostic+marker+for+ovarian+cancer&rft.jtitle=Cancer+Letters&rft.date=Apr+2007&rft.volume=249&rft.issue=1&rft.pages=14%E2%80%937&rft_id=info:pmid/17320281&rft_id=info:doi/10.1016%2Fj.canlet.2006.12.017"><span style="display:none"> </span></span></span> </li> <li id="cite_note-26"><span class="mw-cite-backlink"><a href="#cite_ref-26">↑</a></span> <span class="reference-text"><cite class="book citation" style="font-style:normal"> (2004. október 1.) „Inhibins and ovarian cancer”. <i>Molecular and Cellular Endocrinology</i> <b>225</b> (1-2), 65–71. o. <a href="/wiki/Digital_object_identifier" title="Digital object identifier">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1016/j.mce.2004.02.014">10.1016/j.mce.2004.02.014</a>. <a href="/wiki/PubMed#PubMed-azonosító" title="PubMed">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/15451569">15451569</a>.</cite><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Inhibins+and+ovarian+cancer&rft.jtitle=Molecular+and+Cellular+Endocrinology&rft.date=Oct+2004&rft.volume=225&rft.issue=1-2&rft.pages=65%E2%80%9371&rft_id=info:pmid/15451569&rft_id=info:doi/10.1016%2Fj.mce.2004.02.014"><span style="display:none"> </span></span></span> </li> <li id="cite_note-27"><span class="mw-cite-backlink"><a href="#cite_ref-27">↑</a></span> <span class="reference-text"><cite class="book citation" style="font-style:normal"> (2009. december 1.) „Inhibin B reference data for fertile and infertile men in Northeast America”. <i>Fertility and Sterility</i> <b>92</b> (6), 1920–3. o. <a href="/wiki/Digital_object_identifier" title="Digital object identifier">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1016/j.fertnstert.2008.09.033">10.1016/j.fertnstert.2008.09.033</a>. <a href="/wiki/PubMed#PubMed-azonosító" title="PubMed">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/19006797">19006797</a>.</cite><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Inhibin+B+reference+data+for+fertile+and+infertile+men+in+Northeast+America&rft.jtitle=Fertility+and+Sterility&rft.date=Dec+2009&rft.volume=92&rft.issue=6&rft.pages=1920%E2%80%933&rft_id=info:pmid/19006797&rft_id=info:doi/10.1016%2Fj.fertnstert.2008.09.033"><span style="display:none"> </span></span></span> </li> </ol></div></div><div class="ref-1col"><div style="-moz-column-count:2; -webkit-column-count:2; column-count:2; -webkit-column-gap: 3em; -moz-column-gap: 3em; column-gap: 3em;"></div></div> <div class="mw-heading mw-heading2"><h2 id="Fordítás"><span id="Ford.C3.ADt.C3.A1s"></span>Fordítás</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Aktivin&action=edit&section=11" title="Szakasz szerkesztése: Fordítás"><span>szerkesztés</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li>Ez a szócikk részben vagy egészben az <i><a href="https://en.wikipedia.org/wiki/Activin_and_inhibin" class="extiw" title="en:Activin and inhibin">Activin and inhibin</a></i> című angol Wikipédia-szócikk <span class="plainlinks"><a class="external text" href="https://en.wikipedia.org/wiki/Activin_and_inhibin?oldid=756617276">ezen változatának</a> fordításán alapul.</span> Az eredeti cikk szerkesztőit annak laptörténete sorolja fel. Ez a jelzés csupán a megfogalmazás eredetét és a szerzői jogokat jelzi, nem szolgál a cikkben szereplő információk forrásmegjelöléseként.</li></ul> <div class="navbox-styles"><style data-mw-deduplicate="TemplateStyles:r26593303">.mw-parser-output .hlist dl,.mw-parser-output .hlist ol,.mw-parser-output .hlist ul{margin:0;padding:0}.mw-parser-output .hlist dd,.mw-parser-output .hlist dt,.mw-parser-output .hlist li{margin:0;display:inline}.mw-parser-output .hlist.inline,.mw-parser-output .hlist.inline dl,.mw-parser-output .hlist.inline ol,.mw-parser-output .hlist.inline ul,.mw-parser-output .hlist dl dl,.mw-parser-output .hlist dl ol,.mw-parser-output .hlist dl ul,.mw-parser-output .hlist ol dl,.mw-parser-output .hlist ol ol,.mw-parser-output .hlist ol ul,.mw-parser-output .hlist ul dl,.mw-parser-output .hlist ul ol,.mw-parser-output .hlist ul ul{display:inline}.mw-parser-output .hlist .mw-empty-li{display:none}.mw-parser-output .hlist dt::after{content:": "}.mw-parser-output .hlist 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transparent;border:none;box-shadow:none;padding:0;">sz</span></a></li></ul></div><div id="Endokrin_rendszer:_hormonok_és_hormontermelő_szervek" style="font-size:114%;margin:0 4em"><a href="/wiki/Bels%C5%91_elv%C3%A1laszt%C3%A1s%C3%BA_mirigyek" title="Belső elválasztású mirigyek">Endokrin rendszer</a>: <a href="/wiki/Hormon" title="Hormon">hormonok</a> és hormontermelő szervek</div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i>Koponyaüreg</i></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;"><div style="padding:0em 0.75em;"><a href="/wiki/Hipotalamusz" title="Hipotalamusz">Hipotalamusz</a></div></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Tireotropinfelszabad%C3%ADt%C3%B3_hormon" title="Tireotropinfelszabadító hormon">TRH</a><span style="font-weight:bold;"> ·</span>  <a href="/wiki/Kortikotropinfelszabad%C3%ADt%C3%B3_hormon" title="Kortikotropinfelszabadító hormon">CRH</a><span style="font-weight:bold;"> ·</span>  <a href="/wiki/Gonadotropinfelszabad%C3%ADt%C3%B3_hormon" title="Gonadotropinfelszabadító hormon">GnRH</a><span style="font-weight:bold;"> ·</span>  <a href="/w/index.php?title=N%C3%B6veked%C3%A9si_hormon_releasing_hormon&action=edit&redlink=1" class="new" title="Növekedési hormon releasing hormon (a lap nem létezik)">GHRH</a><span style="font-weight:bold;"> ·</span>  <a href="/wiki/Szomatosztatin" title="Szomatosztatin">szomatosztatin</a><span style="font-weight:bold;"> ·</span>  <a href="/wiki/Dopamin" title="Dopamin">dopamin</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;"><div style="padding:0em 0.75em;"><a href="/wiki/Agyalapi_mirigy" title="Agyalapi mirigy">Hipofízis</a> hátulsó lebenye</div></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Antidiuretikus_hormon" title="Antidiuretikus hormon">vazopresszin</a><span style="font-weight:bold;"> ·</span>  <a href="/wiki/Oxitocin" title="Oxitocin">oxitocin</a><span style="font-weight:bold;"> ·</span>  <a href="/wiki/Lipotropin" title="Lipotropin">lipotropin</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;"><div style="padding:0em 0.75em;">Hipofízis elülső lebenye</div></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/w/index.php?title=Gonadotropin&action=edit&redlink=1" class="new" title="Gonadotropin (a lap nem létezik)">gonadotropinok</a> (<a href="/wiki/Follikuluszstimul%C3%A1l%C3%B3_hormon" title="Follikuluszstimuláló hormon">FSH</a><span style="font-weight:bold;"> ·</span>  <a href="/wiki/Luteiniz%C3%A1l%C3%B3_hormon" title="Luteinizáló hormon">LH</a>)<span style="font-weight:bold;"> ·</span>  <a href="/wiki/Pajzsmirigyserkent%C5%91_hormon" title="Pajzsmirigyserkentő hormon">TSH</a>, <a href="/wiki/N%C3%B6veked%C3%A9si_hormon" title="Növekedési hormon">GH</a><span style="font-weight:bold;"> ·</span>  <a href="/wiki/Prolaktin" title="Prolaktin">prolaktin</a><span style="font-weight:bold;"> ·</span>  <a href="/w/index.php?title=Proopiomelanokortin&action=edit&redlink=1" class="new" title="Proopiomelanokortin (a lap nem létezik)">POMC</a> (→ <a href="/wiki/Adrenokortikotrop_hormon" title="Adrenokortikotrop hormon">ACTH</a><span style="font-weight:bold;"> ·</span>  <a href="/wiki/Melanocitastimul%C3%A1l%C3%B3_hormon" title="Melanocitastimuláló hormon">MSH</a><span style="font-weight:bold;"> ·</span>  <a href="/wiki/Endorfinok" title="Endorfinok">endorfin</a><span style="font-weight:bold;"> ·</span>  <a href="/wiki/Lipotropin" title="Lipotropin">lipotropin</a>)</div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;"><div style="padding:0em 0.75em;"><a href="/wiki/Tobozmirigy" title="Tobozmirigy">Tobozmirigy</a></div></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Melatonin" title="Melatonin">melatonin</a></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i>Nyak</i></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;"><div style="padding:0em 0.75em;"><a href="/wiki/Pajzsmirigy" title="Pajzsmirigy">Pajzsmirigy</a></div></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Pajzsmirigyhormonok" title="Pajzsmirigyhormonok">pajzsmirigyhormonok</a> (<a href="/wiki/Trij%C3%B3d-tironin" class="mw-redirect" title="Trijód-tironin">T<sub>3</sub></a><span style="font-weight:bold;"> ·</span>  <a href="/wiki/Tiroxin" title="Tiroxin">T<sub>4</sub></a>)<span style="font-weight:bold;"> ·</span>  <a href="/wiki/Kalcitonin" title="Kalcitonin">kalcitonin</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;"><div style="padding:0em 0.75em;"><a href="/wiki/Mell%C3%A9kpajzsmirigy" title="Mellékpajzsmirigy">Mellékpajzsmirigy</a></div></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Parathormon" title="Parathormon">PTH</a></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i>Mellüreg</i></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;"><div style="padding:0em 0.75em;"><a href="/wiki/Sz%C3%ADv" title="Szív">Szívpitvar</a></div></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/w/index.php?title=Pitvari_natriuretikus_peptid&action=edit&redlink=1" class="new" title="Pitvari natriuretikus peptid (a lap nem létezik)">ANP</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;"><div style="padding:0em 0.75em;"><a href="/wiki/Csecsem%C5%91mirigy" title="Csecsemőmirigy">Csecsemőmirigy</a></div></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/w/index.php?title=Timozin&action=edit&redlink=1" class="new" title="Timozin (a lap nem létezik)">timozin</a><span style="font-weight:bold;"> ·</span>  <a href="/w/index.php?title=Timopoietin&action=edit&redlink=1" class="new" title="Timopoietin (a lap nem létezik)">timopoietin</a><span style="font-weight:bold;"> ·</span>  <a href="/w/index.php?title=Timulin&action=edit&redlink=1" class="new" title="Timulin (a lap nem létezik)">timulin</a></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i>Hasüreg és <br /> retroperitoneum</i></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;"><div style="padding:0em 0.75em;"><a href="/wiki/Mell%C3%A9kvesevel%C5%91" title="Mellékvesevelő">Mellékvesevelő</a></div></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Adrenalin" title="Adrenalin">adrenalin</a><span style="font-weight:bold;"> ·</span>  <a href="/wiki/Noradrenalin" title="Noradrenalin">noradrenalin</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;"><div style="padding:0em 0.75em;"><a href="/wiki/Mell%C3%A9kvesek%C3%A9reg" title="Mellékvesekéreg">Mellékvesekéreg</a></div></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Aldoszteron" title="Aldoszteron">aldoszteron</a><span style="font-weight:bold;"> ·</span>  <a href="/wiki/Hidrokortizon" title="Hidrokortizon">hidrokortizon</a><span style="font-weight:bold;"> ·</span>  <a href="/w/index.php?title=Dehidroepiandroszteron&action=edit&redlink=1" class="new" title="Dehidroepiandroszteron (a lap nem létezik)">DHEA</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;"><div style="padding:0em 0.75em;"><a href="/wiki/Vese" title="Vese">Vese</a></div></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Renin" title="Renin">renin</a><span style="font-weight:bold;"> ·</span>  <a href="/wiki/Eritropoetin" title="Eritropoetin">eritropoetin</a><span style="font-weight:bold;"> ·</span>  <a href="/w/index.php?title=Kalcitriol&action=edit&redlink=1" class="new" title="Kalcitriol (a lap nem létezik)">kalcitriol</a><span style="font-weight:bold;"> ·</span>  <a href="/wiki/Prosztaglandin" title="Prosztaglandin">prosztaglandin</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;"><div style="padding:0em 0.75em;"><a href="/wiki/M%C3%A1j" title="Máj">Máj</a></div></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/w/index.php?title=Inzulinszer%C5%B1_n%C3%B6veked%C3%A9si_faktor_1&action=edit&redlink=1" class="new" title="Inzulinszerű növekedési faktor 1 (a lap nem létezik)">IGF-1</a><span style="font-weight:bold;"> ·</span>  <a href="/wiki/Angiotenzin#Angiotenzinogén" title="Angiotenzin">angiotenzinogén</a><span style="font-weight:bold;"> ·</span>  <a href="/w/index.php?title=Kalcidiol&action=edit&redlink=1" class="new" title="Kalcidiol (a lap nem létezik)">kalcidiol</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;"><div style="padding:0em 0.75em;"><a href="/wiki/Hasny%C3%A1lmirigy" title="Hasnyálmirigy">Hasnyálmirigy</a> <a href="/wiki/Langerhans-szigetek" class="mw-redirect" title="Langerhans-szigetek">Langerhans-szigetek</a></div></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Glukagon" title="Glukagon">glukagon</a><span style="font-weight:bold;"> ·</span>  <a href="/wiki/Inzulin" title="Inzulin">inzulin</a><span style="font-weight:bold;"> ·</span>  <a href="/wiki/Szomatosztatin" title="Szomatosztatin">szomatosztatin</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;"><div style="padding:0em 0.75em;"><a href="/wiki/Gyomor" title="Gyomor">Gyomor</a></div></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Gasztrin" title="Gasztrin">gasztrin</a><span style="font-weight:bold;"> ·</span>  <a href="/wiki/Ghrelin" title="Ghrelin">ghrelin</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;"><div style="padding:0em 0.75em;"><a href="/wiki/Patk%C3%B3b%C3%A9l" title="Patkóbél">Patkóbél</a></div></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Kolecisztokinin" title="Kolecisztokinin">CCK</a><span style="font-weight:bold;"> ·</span>  <a href="/w/index.php?title=Gastric_inhibitory_polypeptide&action=edit&redlink=1" class="new" title="Gastric inhibitory polypeptide (a lap nem létezik)">GIP</a><span style="font-weight:bold;"> ·</span>  <a href="/w/index.php?title=Szekretin&action=edit&redlink=1" class="new" title="Szekretin (a lap nem létezik)">szekretin</a><span style="font-weight:bold;"> ·</span>  <a href="/w/index.php?title=Motilin&action=edit&redlink=1" class="new" title="Motilin (a lap nem létezik)">motilin</a><span style="font-weight:bold;"> ·</span>  <a href="/w/index.php?title=Vazoakt%C3%ADv_intesztin%C3%A1lis_peptid&action=edit&redlink=1" class="new" title="Vazoaktív intesztinális peptid (a lap nem létezik)">VIP</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;"><div style="padding:0em 0.75em;"><a href="/wiki/Cs%C3%ADp%C5%91b%C3%A9l" title="Csípőbél">Csípőbél</a></div></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/w/index.php?title=Enteroglukagon&action=edit&redlink=1" class="new" title="Enteroglukagon (a lap nem létezik)">enteroglukagon</a></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i>Nemi szervek</i></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;"><div style="padding:0em 0.75em;"><a href="/wiki/Here_(anat%C3%B3mia)" title="Here (anatómia)">Here</a></div></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Tesztoszteron" title="Tesztoszteron">tesztoszteron</a><span style="font-weight:bold;"> ·</span>  <a href="/w/index.php?title=Anti-m%C3%BCller_hormon&action=edit&redlink=1" class="new" title="Anti-müller hormon (a lap nem létezik)">AMH</a><span style="font-weight:bold;"> ·</span>  <a href="/wiki/Inhibin" class="mw-redirect" title="Inhibin">inhibin</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;"><div style="padding:0em 0.75em;"><a href="/wiki/Petef%C3%A9szek" title="Petefészek">Petefészek</a></div></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/%C3%96sztradiol" title="Ösztradiol">ösztradiol</a><span style="font-weight:bold;"> ·</span>  <a href="/wiki/S%C3%A1rgatesthormon" title="Sárgatesthormon">progeszteron</a><span style="font-weight:bold;"> ·</span>  <a class="mw-selflink selflink">inhibin</a><span style="font-weight:bold;"> ·</span>  <a class="mw-selflink selflink">aktivin</a><span style="font-weight:bold;"> ·</span>  <a href="/w/index.php?title=Relaxin&action=edit&redlink=1" class="new" title="Relaxin (a lap nem létezik)">relaxin</a> (terhesség)</div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;"><div style="padding:0em 0.75em;"><a href="/wiki/M%C3%A9hlep%C3%A9ny" title="Méhlepény">Méhlepény</a></div></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/w/index.php?title=Human_chorion_gonadotropin&action=edit&redlink=1" class="new" title="Human chorion gonadotropin (a lap nem létezik)">hCG</a><span style="font-weight:bold;"> ·</span>  <a href="/w/index.php?title=Human_placental_lactogen&action=edit&redlink=1" class="new" title="Human placental lactogen (a lap nem létezik)">HPL</a><span style="font-weight:bold;"> ·</span>  <a href="/wiki/T%C3%BCsz%C5%91hormon" title="Tüszőhormon">ösztrogén</a><span style="font-weight:bold;"> ·</span>  <a href="/wiki/S%C3%A1rgatesthormon" title="Sárgatesthormon">progeszteron</a></div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><i>Egyéb</i></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;"><div style="padding:0em 0.75em;"><a href="/wiki/Zs%C3%ADrsz%C3%B6vet" title="Zsírszövet">Zsírszövet</a></div></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Leptin" title="Leptin">leptin</a><span style="font-weight:bold;"> ·</span>  <a href="/w/index.php?title=Adiponektin&action=edit&redlink=1" class="new" title="Adiponektin (a lap nem létezik)">adiponektin</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;"><div style="padding:0em 0.75em;"><a href="/wiki/B%C5%91r_(anat%C3%B3mia)" title="Bőr (anatómia)">Bőr</a></div></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/w/index.php?title=Previtamin_D3&action=edit&redlink=1" class="new" title="Previtamin D3 (a lap nem létezik)">previtamin D3</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;"><div style="padding:0em 0.75em;"><a href="/wiki/%C3%89r_(anat%C3%B3mia)" title="Ér (anatómia)">Érfal</a>, <a href="/wiki/V%C3%A9rplazma" title="Vérplazma">vérplazma</a></div></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/wiki/Angiotenzin#Angiotenzin_I" title="Angiotenzin">angiotenzin I</a><span style="font-weight:bold;"> ·</span>  <a href="/wiki/Angiotenzin#Angiotenzin_II" title="Angiotenzin">angiotenzin II</a></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;padding-left:0em;padding-right:0em;"><div style="padding:0em 0.75em;">Target-derived</div></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><a href="/w/index.php?title=Nerve_growth_factor&action=edit&redlink=1" class="new" title="Nerve growth factor (a lap nem létezik)">NGF</a><span style="font-weight:bold;"> ·</span>  <a href="/w/index.php?title=Brain-derived_neurotrophic_factor&action=edit&redlink=1" class="new" title="Brain-derived neurotrophic factor (a lap nem létezik)">BDNF</a><span style="font-weight:bold;"> ·</span>  <a href="/w/index.php?title=NT-3&action=edit&redlink=1" class="new" title="NT-3 (a lap nem létezik)">NT-3</a></div></td></tr></tbody></table><div></div></td></tr></tbody></table></div> <div class="noprint noviewer" style="overflow: hidden; clear: both;"><div style="margin-left:3px; margin-right:3px;"><ul style="display:block; list-style-image:none; list-style-type:none; width:100%; vertical-align:middle; margin:0; padding:0; min-height: 27px;"><li style="float:left; min-height: 27px; line-height:25px; width:49%; margin:0; margin-top:.5em; margin-left:-3px; margin-right:1%; padding:0; border:1px solid #CCF; background-color:#F0EEFF"><span typeof="mw:File"><a href="/wiki/F%C3%A1jl:Caduceus_-_black.png" class="mw-file-description" 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