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Pairwise kinship inference and pedigree reconstruction using 91 microhaplotypes - Peeref
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<strong>My Account</strong> </a> </li> </ul> <ul class="nav navbar-nav navbar-right" style="display: inline-flex; align-items: center; margin-left: 20px;"> <li id="language"> <a href="javascript:"> <div class="current"> <i class="ivu-icon ivu-icon-md-globe"></i> EN </div> </a> <div class="selection"> <a rel="alternate" hreflang="en" href="https://www.peeref.com/works/82931435" > <span>English</span> </a> <a rel="alternate" hreflang="zh" href="https://www.peeref.com/zh/works/82931435" > <span>中文</span> </a> </div> </li> </ul> </ul> </div> </nav> <main> <div id="top-info-banner" class="container-fluid mb-0"> <div class="container"> <div class="d-flex align-items-center" style="margin-top: 30px;"> <span class="text-white"> <strong class="f18">☆</strong> <span class="f16">4.7</span> </span> <span class="mx-3"></span> <span class="tag">Article</span> </div> <h1 class="title title-for-article"> Pairwise kinship inference and pedigree reconstruction using 91 microhaplotypes </h1> <div class="help-links-left"> <p class="pub-info"> FOOD AND CHEMICAL TOXICOLOGY (2024) </p> </div> </div> </div> <div id="article-sticky-navbar"> <div class="container"> <div class="d-flex justify-content-between flex-wrap flex-md-nowrap"> <div class="d-flex align-items-center mb-2"> <ul class="nav nav-underline f16 font-weight-bold"> <li class="active"> <a href="javascript:;"> Overview </a> </li> <li class=""> <a href="https://www.peeref.com/works/82931435/comments"> Write a Review </a> </li> </ul> </div> <div class="d-flex align-items-center justify-content-md-end flex-wrap flex-md-nowrap"> <div class="mr-3 mt-3 mt-md-0 flex-shrink-0"> <a href="https://doi.org/10.1016/j.fsigen.2024.103090" target="_blank" class="btn btn-warning btn-circle"> <i class="ivu-icon ivu-icon-md-copy f16"></i> <strong>Get Full Text</strong> </a> </div> <div class="mr-3 mt-3 mt-md-0 flex-shrink-0"> <a href="https://www.peeref.com/works/82931435/add-to-collection" class="btn btn-success btn-circle"> <strong>Add to 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<div id="article-details" class="container"> <div class="col-md-4 px-0 pr-md-3"> <div class="f15 panel-box rounded shadow-none border"> <div class="mb-3 pb-3"> <h4 class="mt-0">Journal</h4> <div class="f16"> <h5 class="title f16"> <a href="https://www.peeref.com/journals/2886/food-and-chemical-toxicology"> FOOD AND CHEMICAL TOXICOLOGY </a> </h5> <span> Volume 191, Issue -, Pages - </span> </div> </div> <div class="mb-3 pb-3"> <h4 class="mt-0">Publisher</h4> <div class="f16"> <h5 class="title f16 text-primary"> PERGAMON-ELSEVIER SCIENCE LTD </h5> <div class="my-2"> DOI: 10.1016/j.fsigen.2024.103090 </div> </div> </div> <div class="mb-3 pb-3"> <h4 class="mt-0">Keywords</h4> <div class="f16"> Relatedness; Kinship; Microhaplotypes (MH); Likelihood ratio (LR); Pedigree </div> </div> <div class="mb-3 pb-3"> <h4 class="mt-0">Categories</h4> <div class="f16"> <span class="d-block"> <a href="https://www.peeref.com/works/list?category=Food+Science+%26+Technology" target="_blank" class="text-dark btn btn-link p-0 text-left"> Food Science & Technology </a> </span> <span class="d-block"> <a href="https://www.peeref.com/works/list?category=Toxicology" target="_blank" class="text-dark btn btn-link p-0 text-left"> Toxicology </a> </span> </div> </div> <div class="mb-3 pb-3"> <h4 class="mt-0">Funding</h4> <div class="f16"> <ol class=""> <li>National Natural Science Foundation of China [82230064, 82072120, 81630054]</li> </ol> </div> </div> </div> <div class="f15 panel-box rounded shadow-none border"> <h4 class="mt-0 text-center">Ask authors/readers for more resources</h4> <div class="requests"> <div class="requests-item"> <div class="icon"> <img src="https://peeref-open.s3.amazonaws.com/images/file.png" alt=""> </div> <h4>Protocol</h4> <p> <a href="https://www.peeref.com/works/82931435/resource" class="btn btn-outline-primary btn-sm"> Community support </a> </p> </div> <div class="requests-item"> <div class="icon"> <img src="https://peeref-open.s3.amazonaws.com/images/experiment.png" alt=""> </div> <h4>Reagent</h4> <p> <a href="https://www.peeref.com/works/82931435/resource" class="btn btn-outline-primary btn-sm"> Community support </a> </p> </div> </div> </div> </div> <div class="col-md-8 px-0 pl-md-3"> <div id="article-summary-panel" class="mb-4"> <ul class="nav nav-tabs" style="list-style: none; padding-left: 0;"> <li class="active"> <a href="#ai_summary" data-toggle="tab" class="summary-tab mx-0 f16 text-dark"> <strong>Automated Summary</strong> <strong class="text-danger ml-1"><i>New</i></strong> </a> </li> <li class=""> <a href="#raw_abstract" data-toggle="tab" class="abstract-tab mx-0 f16 text-dark"> <strong>Abstract</strong> </a> </li> </ul> <div class="tab-content border border-top-0"> <div id="ai_summary" class="tab-pane active"> <div class="summary-panel panel-box mb-0 rounded shadow-none"> <div class="f16">This study addresses the issue of kinship inference when there are no prior assumptions and the relationships between multiple individuals are unknown. It uses genotyping and likelihood ratio calculation to infer relatedness and reconstruct pedigrees. The results show that 91 microhaplotypes can discriminate second-degree relatives from unrelated individuals, and more loci are needed to distinguish more distant relatives. Correct classification can be achieved by expanding the suspected relationships. This study provides a new solution for kinship inference.</div> </div> </div> <div id="raw_abstract" class="tab-pane "> <div class="abstract-panel panel-box mb-0 rounded shadow-none"> <div class="f16">Kinship inference has been a major issue in forensic genetics, and it remains to be solved when there is no prior hypothesis and the relationships between multiple individuals are unknown. In this study, we genotyped 91 microhaplotypes from 46 pedigree samples using massive parallel sequencing and inferred their relatedness by calculating the likelihood ratio (LR). Based on simulated and real data, different treatments were applied in the presence and absence of relatedness assumptions. The pedigree of multiple individuals was reconstructed by calculating pedigree likelihoods based on real pedigree samples. The results showed that the 91 MHs could discriminate pairs of second-degree relatives from unrelated individuals. And more highly polymorphic loci were needed to discriminate the pairs of second-degree or more distant relative from other degrees of relationship, but correct classification could be obtained by expanding the suspected relationship searched to other relationships with lower LR values. Multiple individuals with unknown relationships can be successfully reconstructed if they are closely related. Our study provides a solution for kinship inference when there are no prior assumptions, and explores the possibility of pedigree reconstruction when the relationships of multiple individuals are unknown.</div> </div> </div> </div> </div> <div class="f15 panel-box rounded shadow-none border"> <h4 class="mt-0 heading-count">Authors</h4> <div class="mb-3"> <article-authors tid="82931435" list="[{"name":"Yifan Wei","sequence":1},{"name":"Qiang Zhu","sequence":2},{"name":"Haoyu Wang","sequence":3},{"name":"Yueyan Cao","sequence":4},{"name":"Xi Li","sequence":5},{"name":"Xiaokang Zhang","sequence":6},{"name":"Yufang Wang","sequence":7},{"name":"Ji Zhang","sequence":8}]" verified="[]" page="work" ></article-authors> </div> <div class="alert alert-warning mb-0"> <h5 class="mt-0 bg-warning text-dark px-3 rounded d-inline-block"> I am an author on this paper </h5> <div class="font-weight-bold f13"> Click your name to claim this paper and add it to your profile. </div> </div> </div> <div class="f15 panel-box rounded shadow-none border"> <h4 class="mt-0 heading-count">Reviews</h4> <div class="d-flex flex-wrap flex-md-nowrap"> <div class="flex-grow-1"> <h4 class="f16"> Primary Rating <a href="javascript:;" data-toggle="tooltip" data-placement="right" title="The primary rating indicates the level of overall quality for the paper."> <i class="ivu-icon ivu-icon-md-help-circle f18 ml-2"></i> </a> </h4> <div class="d-flex flex-wrap flex-md-nowrap align-items-center alert mb-0"> <div class="d-flex align-items-center justify-content-center"> <Rate disabled allow-half value="4.7" style="font-size: 28px;"></Rate> <strong class="f20 m-3" style="color: #f5a623;">4.7</strong> </div> <div class="text-muted mx-4"> Not enough ratings </div> </div> <h4 class="f16"> Secondary Ratings <a href="javascript:;" data-toggle="tooltip" data-placement="right" title="Secondary ratings independently reflect strengths or weaknesses of the paper."> <i class="ivu-icon ivu-icon-md-help-circle f18 ml-2"></i> </a> </h4> <div class="d-flex flex-wrap flex-md-nowrap alert"> <div class="d-flex flex-shrink-0 align-items-center mr-3"> <h5 class="my-0">Novelty</h5> <strong class="mx-4">-</strong> </div> <div class="d-flex flex-shrink-0 align-items-center mr-3"> <h5 class="my-0">Significance</h5> <strong class="mx-4">-</strong> </div> <div class="d-flex flex-shrink-0 align-items-center mr-3"> <h5 class="my-0">Scientific rigor</h5> <strong class="mx-4">-</strong> </div> </div> </div> <div class="flex-shrink-0"> <div class="border bg-light py-2 px-4"> <h5 class="mb-1">Rate this paper</h5> <Rate class="f24" @on-change="function(value){ location.href='https://www.peeref.com/works/82931435/comments?rating='+value }"></Rate> </div> </div> </div> </div> <div id="collection" class="f15 panel-box rounded shadow-none border"> <h4 class="mt-0 heading-count">Recommended</h4> <div class="my-3"> <ul class="nav nav-pills border-bottom pb-3" style="list-style: none; padding-left: 0;"> <li class="active"> <a href="#articles_from_related" data-toggle="tab" class="mx-0 f15"> <strong>Related</strong> </a> </li> <li class=""> <a href="#articles_from_authors" data-toggle="tab" class="mx-0 f15"> <strong>From Same Authors</strong> </a> </li> <li class=""> <a href="#articles_from_journal" data-toggle="tab" class="mx-0 f15"> <strong>From Same Journal</strong> </a> </li> </ul> <div class="tab-content"> <div id="articles_from_related" class="tab-pane active"> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Genetics & Heredity </span> </div> <h4> <a href="https://www.peeref.com/works/82936722" class="text-dark hover-underline">Pairwise kinship inference and pedigree reconstruction using 91 microhaplotypes</a> </h4> <p class="text-ellipsis-2">Yifan Wei, Qiang Zhu, Haoyu Wang, Yueyan Cao, Xi Li, Xiaokang Zhang, Yufang Wang, Ji Zhang</p> <div class="d-flex mb-3"> <div class="flex-shrink-0 d-none d-sm-block"> <img src="https://peeref-open.s3.amazonaws.com/storage/images/covers/2908.jpg" alt="" class="border mr-3" width="100"> </div> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> This study solves the problem of kinship inference without prior assumptions by genotyping and calculating the likelihood ratio to infer the relatedness of individuals. It is found that increasing the number of polymorphic loci can improve the accuracy of kinship inference, and correct classification can be achieved by expanding the suspected relationship. In addition, this method can also be used to reconstruct the pedigree of multiple individuals with unknown relationships. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">FORENSIC SCIENCE INTERNATIONAL-GENETICS</span> (2024) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/82936722/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Multidisciplinary Sciences </span> </div> <h4> <a href="https://www.peeref.com/works/28855387" class="text-dark hover-underline">Kinship composition in mammals</a> </h4> <p class="text-ellipsis-2">Andre S. Pereira, Delphine De Moor, Catarina Casanova, Lauren J. N. Brent</p> <div class="d-flex mb-3"> <div class="flex-shrink-0 d-none d-sm-block"> <img src="https://peeref-open.s3.amazonaws.com/storage/images/covers/10246.jpg" alt="" class="border mr-3" width="100"> </div> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> Understanding the evolution of group-living and cooperation requires knowledge of the kinship composition in animal groups. This study presents initial findings on the kinship composition of mammalian groups, showing that social mammals often live with unrelated individuals of the same sex. These results emphasize the importance of considering both indirect and direct fitness benefits in the evolution of sociality. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">ROYAL SOCIETY OPEN SCIENCE</span> (2023) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/28855387/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Biotechnology & Applied Microbiology </span> </div> <h4> <a href="https://www.peeref.com/works/27217671" class="text-dark hover-underline">Inferring biological kinship in ancient datasets: comparing the response of ancient DNA-specific software packages to low coverage data</a> </h4> <p class="text-ellipsis-2">William A. Marsh, Selina Brace, Ian Barnes</p> <div class="d-flex mb-3"> <div class="flex-shrink-0 d-none d-sm-block"> <img src="https://peeref-open.s3.amazonaws.com/storage/images/covers/1255.jpg" alt="" class="border mr-3" width="100"> </div> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> The use of archaeogenetic techniques, in combination with traditional methods, allows for improved interpretation of burial practices, cultural behaviors, and societal stratification in ancient societies. However, questions remain regarding the accuracy of these techniques, especially when it comes to low coverage datasets obtained from degraded ancient material. A study comparing six commonly used kinship identification software methods revealed differences in performance, emphasizing the importance of applying multiple methods for authentication of kin relationships in ancient material. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">BMC GENOMICS</span> (2023) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/27217671/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Genetics & Heredity </span> </div> <h4> <a href="https://www.peeref.com/works/83039808" class="text-dark hover-underline">Application of a newly constructed NGS panel with 45 X-linked microhaplotypes demonstrates the unique value of X-MH for kinship testing and mixture analysis</a> </h4> <p class="text-ellipsis-2">Guanju Ma, Kailiang Liu, Chaolong Lu, Qingqing Du, Mengjie Zhang, Qian Wang, Guangping Fu, Junyan Wang, Chunling Ma, Bin Cong, Shujin Li, Lihong Fu</p> <div class="d-flex mb-3"> <div class="flex-shrink-0 d-none d-sm-block"> <img src="https://peeref-open.s3.amazonaws.com/storage/images/covers/2908.jpg" alt="" class="border mr-3" width="100"> </div> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> This study screened 63 X-MHs, evaluated their performance, and calculated population parameters. The panel performed well in personal identification and paternity testing, and showed unique advantages in complex kinship and male DNA mixture analyses. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">FORENSIC SCIENCE INTERNATIONAL-GENETICS</span> (2024) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/83039808/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Genetics & Heredity </span> </div> <h4> <a href="https://www.peeref.com/works/25558075" class="text-dark hover-underline">State of the Art for Microhaplotypes</a> </h4> <p class="text-ellipsis-2">Kenneth K. Kidd, Andrew J. Pakstis</p> <div class="d-flex mb-3"> <div class="flex-shrink-0 d-none d-sm-block"> <img src="https://peeref-open.s3.amazonaws.com/storage/images/covers/9770.jpg" alt="" class="border mr-3" width="100"> </div> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> In recent years, there has been a significant increase in the number of publications on microhaplotypes, which have proven to be highly informative in various areas of forensic DNA analysis. Microhaplotypes can be measured using different indicators and have important applications in parentage testing and missing persons cases. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">GENES</span> (2022) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/25558075/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Biochemical Research Methods </span> </div> <h4> <a href="https://www.peeref.com/works/26436098" class="text-dark hover-underline">Privacy-aware estimation of relatedness in admixed populations</a> </h4> <p class="text-ellipsis-2">Su Wang, Miran Kim, Wentao Li, Xiaoqian Jiang, Han Chen, Arif Harmanci</p> <div class="d-flex mb-3"> <div class="flex-shrink-0 d-none d-sm-block"> <img src="https://peeref-open.s3.amazonaws.com/storage/images/covers/1344.jpg" alt="" class="border mr-3" width="100"> </div> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> The study introduces a projection-based approach called SIGFRIED to simplify kinship estimation in admixed populations. The accuracy and efficiency of the method are demonstrated using simulated and real datasets. A secure federated kinship estimation framework is proposed, along with a secure kinship estimator using homomorphic encryption-based primitives. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">BRIEFINGS IN BIOINFORMATICS</span> (2022) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/26436098/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Evolutionary Biology </span> </div> <h4> <a href="https://www.peeref.com/works/33834539" class="text-dark hover-underline">Implications of methodologies for integrating empirical kinships into ex situ population management using PMx: A case study of Baer's Pochard (Aythya baeri) in North America</a> </h4> <p class="text-ellipsis-2">Asako Y. Chaille, Robert C. Lacy, Andrea S. Putnam, Jamie L. Toste, Aryn P. Wilder, Jamie A. Ivy</p> <div class="d-flex mb-3"> <div class="flex-shrink-0 d-none d-sm-block"> <img src="https://peeref-open.s3.amazonaws.com/storage/images/covers/4624.jpg" alt="" class="border mr-3" width="100"> </div> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> The integration of empirical kinships into the genetic management of ex situ populations can impact genetic summary statistics and highlights the importance of understanding the scale of molecular kinships. This study focuses on Baer's pochard and provides guidance on incorporating empirical kinships into population management. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">JOURNAL OF HEREDITY</span> (2023) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/33834539/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Genetics & Heredity </span> </div> <h4> <a href="https://www.peeref.com/works/24609598" class="text-dark hover-underline">Streamlining the decision-making process for international DNA kinship matching using Worldwide allele frequencies and tailored cutoff log10LR thresholds</a> </h4> <p class="text-ellipsis-2">Francois-Xavier Laurent, Andrea Fischer, Robert F. Oldt, Sree Kanthaswamy, John S. Buckleton, Susan Hitchin</p> <div class="d-flex mb-3"> <div class="flex-shrink-0 d-none d-sm-block"> <img src="https://peeref-open.s3.amazonaws.com/storage/images/covers/2908.jpg" alt="" class="border mr-3" width="100"> </div> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> The identification of human remains belonging to missing persons is a challenge for forensic genetics, with DNA being a valuable tool for supporting potential associations. Indirect identification through DNA from missing person's relatives is common in cases where reference DNA samples cannot be collected. While implementing DNA kinship matching nationally is feasible, challenges need to be addressed before applying this method internationally. This study introduces a method for international DNA kinship matching, aiding in the classification of potential candidates based on DNA evidence strength and reducing adventitious matches in missing person investigations. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">FORENSIC SCIENCE INTERNATIONAL-GENETICS</span> (2022) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/24609598/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Medicine, Legal </span> </div> <h4> <a href="https://www.peeref.com/works/22497672" class="text-dark hover-underline">Pairwise kinship testing with microhaplotypes: Can advancements be made in kinship inference with these markers?</a> </h4> <p class="text-ellipsis-2">Riga Wu, Hui Chen, Ran Li, Yu Zang, Xuefeng Shen, Bo Hao, Qiangwei Wang, Hongyu Sun</p> <div class="d-flex mb-3"> <div class="flex-shrink-0 d-none d-sm-block"> <img src="https://peeref-open.s3.amazonaws.com/storage/images/covers/2907.jpg" alt="" class="border mr-3" width="100"> </div> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> The study found that 54 highly polymorphic microhaplotypes are reliable for first-degree relationship testing, but not sufficient for distant relationship testing. Therefore, more markers need to be added to improve the accuracy of kinship testing. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">FORENSIC SCIENCE INTERNATIONAL</span> (2021) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/22497672/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Genetics & Heredity </span> </div> <h4> <a href="https://www.peeref.com/works/21292460" class="text-dark hover-underline">Distinguishing pedigree relationships via multi-way identity by descent sharing and sex-specific genetic maps</a> </h4> <p class="text-ellipsis-2">Ying Qiao, Jens G. Sannerud, Sayantani Basu-Roy, Caroline Hayward, Amy L. Williams</p> <div class="d-flex mb-3"> <div class="flex-shrink-0 d-none d-sm-block"> <img src="https://peeref-open.s3.amazonaws.com/storage/images/covers/424.jpg" alt="" class="border mr-3" width="100"> </div> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> The study highlights the importance of relatedness modeling and pedigree-based analyses in genetic datasets with multiple close relatives. CREST, an accurate and fast method, effectively identifies pedigree relationships among close relatives, outperforming traditional methods in classifying different types of kinship relationships. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">AMERICAN JOURNAL OF HUMAN GENETICS</span> (2021) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/21292460/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Genetics & Heredity </span> </div> <h4> <a href="https://www.peeref.com/works/26795527" class="text-dark hover-underline">Two-locus identity coefficients in pedigrees</a> </h4> <p class="text-ellipsis-2">Magnus Dehli Vigeland</p> <div class="d-flex mb-3"> <div class="flex-shrink-0 d-none d-sm-block"> <img src="https://peeref-open.s3.amazonaws.com/storage/images/covers/8818.jpg" alt="" class="border mr-3" width="100"> </div> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> This paper proposes a solution to a long-standing problem of joint distribution of allelic identity by descent between two individuals at two linked loci. The recursive algorithm described in this paper and its implementation in R allow efficient calculation of two-locus identity coefficients in any pedigree. This enables the application of existing procedures and techniques to complex and inbred relationships. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">G3-GENES GENOMES GENETICS</span> (2023) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/26795527/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Behavioral Sciences </span> </div> <h4> <a href="https://www.peeref.com/works/27204001" class="text-dark hover-underline">Turnover in male dominance offsets the positive effect of polygyny on within-group relatedness</a> </h4> <p class="text-ellipsis-2">Mark Dyble, Tim H. Clutton-Brock</p> <div class="d-flex mb-3"> <div class="flex-shrink-0 d-none d-sm-block"> <img src="https://peeref-open.s3.amazonaws.com/storage/images/covers/1045.jpg" alt="" class="border mr-3" width="100"> </div> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> In species with polygynous mating systems, the high male reproductive skew and frequent changes in male dominance due to intense competition between males may not necessarily increase average genetic relatedness within groups. Previous studies have suggested an association between cooperative breeding systems and average coefficients of relatedness in vertebrates, but in multiparous polygynous animals with intense male competition, paternal relatedness and average kinship between multigenerational group members are reduced due to frequent male turnover. A theoretical model shows that increases in turnover rates of breeding males in polygynous systems can offset the positive effect of male skew on relatedness within seasons, suggesting that polygynous mating systems may not necessarily lead to significant increases in average relatedness, especially when there is extensive overlap between generations among group members. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">BEHAVIORAL ECOLOGY</span> (2023) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/27204001/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Forestry </span> </div> <h4> <a href="https://www.peeref.com/works/23951761" class="text-dark hover-underline">Kinship Analysis and Pedigree Reconstruction of a Natural Regenerated Cork Oak (Quercus suber) Population</a> </h4> <p class="text-ellipsis-2">Bruna Mendes, Teresa Sampaio, Marta A. Antunes, Hugo Magalhaes, Filipe Costa e Silva, Carla Borges, Fernanda Simoes, Ana Usie, Maria Helena Almeida, Antonio Marcos Ramos</p> <div class="d-flex mb-3"> <div class="flex-shrink-0 d-none d-sm-block"> <img src="https://peeref-open.s3.amazonaws.com/storage/images/covers/8812.jpg" alt="" class="border mr-3" width="100"> </div> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> This study investigates the potential of using SNP genotyping to predict kinship and reconstruct pedigrees in a natural cork oak population. By genotyping a total of 494 trees, the study reveals a large number of relationships among individuals, demonstrating the importance of SNP genotyping in cork oak breeding and conservation programs. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">FORESTS</span> (2022) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/23951761/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Biochemical Research Methods </span> </div> <h4> <a href="https://www.peeref.com/works/25266820" class="text-dark hover-underline">QuickPed: an online tool for drawing pedigrees and analysing relatedness</a> </h4> <p class="text-ellipsis-2">Magnus D. Vigeland</p> <div class="d-flex mb-3"> <div class="flex-shrink-0 d-none d-sm-block"> <img src="https://peeref-open.s3.amazonaws.com/storage/images/covers/1243.jpg" alt="" class="border mr-3" width="100"> </div> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> QuickPed is a user-friendly pedigree tool aimed at researchers, case workers, and teachers. It contains features not found in other similar tools and makes advanced relatedness analyses available for non-bioinformaticians. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">BMC BIOINFORMATICS</span> (2022) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/25266820/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> <div class="my-4 "> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Genetics & Heredity </span> </div> <h4> <a href="https://www.peeref.com/works/26836912" class="text-dark hover-underline">Compound and Conditioned Likelihood Ratio Behavior within a Probabilistic Genotyping Context</a> </h4> <p class="text-ellipsis-2">Kyle Duke, Daniela Cuenca, Steven Myers, Jeanette Wallin</p> <div class="d-flex mb-3"> <div class="flex-shrink-0 d-none d-sm-block"> <img src="https://peeref-open.s3.amazonaws.com/storage/images/covers/9770.jpg" alt="" class="border mr-3" width="100"> </div> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> In DNA mixture analysis, comparing compound likelihood ratios and simple likelihood ratio products can help evaluate the contribution of questioned individuals to mixed DNA. The study found that the magnitude of increase in likelihood ratios depends on the proportion and input of DNA mixture. The impact of constrained genotype combinations on the outcome of likelihood ratio calculations is comparable whether the restriction is applied before or after interpretation. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">GENES</span> (2022) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/26836912/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> </div> <div id="articles_from_authors" class="tab-pane "> <div class="nodata my-4">No Data Available</div> </div> <div id="articles_from_journal" class="tab-pane "> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Food Science & Technology </span> </div> <h4> <a href="https://www.peeref.com/works/83134402" class="text-dark hover-underline">Characterization, hazard identification, and risk assessment of volatile organic compounds in Poly(butylene adipate-co-terephthalate)-based food contact articles</a> </h4> <p class="text-ellipsis-2">Hanke Li, Hongjian Miao, Lichang Chen, Qi-Zhi Su, Zhenwei Liu, Canghao Xie, Jinxin Liang, Siliang Wu, An-Qi Cui, Can Xu, Ben Dong, Dan Li, Sheng Chen, Huai-Ning Zhong, Jianguo Zheng</p> <div class="d-flex mb-3"> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> This study characterized and assessed the risks of volatile organic compounds in PBAT-based food contact articles, and found that some of these compounds have genotoxic or carcinogenic hazards, which require prioritized attention to improve their chemical safety. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">FOOD AND CHEMICAL TOXICOLOGY</span> (2024) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/83134402/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Food Science & Technology </span> </div> <h4> <a href="https://www.peeref.com/works/83085673" class="text-dark hover-underline">Concentration and health risk assessment of 16 rare earth elements in six types of tea in China</a> </h4> <p class="text-ellipsis-2">Tong Ou, Hanbing Bao, Yujing Zhou, Zhaoping Liu, Haixia Sui, Ling Yong, Weifeng Mao, Yibaina Wang, Huihui Bao, Xiao Xiao, Lei Zhang, Dajin Yang, Dingguo Jiang, Ning Li, Sheng Wei, Yan Song</p> <div class="d-flex mb-3"> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> This study analyzed the concentration of rare earth elements in Chinese tea and the associated health risks for consumers. The results showed that the content of 16 REEs in tea was similar, with the highest level in oolong tea. The concentration of LREEs was higher than that of HREEs. The intake of REEs from tea by the general population in China was much lower than the provisional tolerable daily intake, posing no known health risks. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">FOOD AND CHEMICAL TOXICOLOGY</span> (2024) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/83085673/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Food Science & Technology </span> </div> <h4> <a href="https://www.peeref.com/works/83136487" class="text-dark hover-underline">Changes in PI3K/AKT and NRF2/HO-1 signaling expression and intestinal microbiota in bleomycin-induced pulmonary fibrosis</a> </h4> <p class="text-ellipsis-2">Chenchen Li, Yuxia Cao, Yousheng Peng, Ting Ma, Fanlin Wu, Yongli Hua, Xiuqin Wang, Tong Bai, Yanming Wei, Peng Ji</p> <div class="d-flex mb-3"> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> This study established a novel bleomycin-induced pulmonary fibrosis rat model and found that the model showed widened alveolar septum, infiltration of inflammatory cells, alveolar atrophy, and distribution of fibrous tissue, accompanied by decreased mRNA expression of HO-1 and NRF2, increased mRNA expression of HIF-1α, VEGF, PI3K, and AKT, decreased protein expression of E-cad, HO-1, and NRF2, increased protein expression of α-SMA and p-AKT, and imbalance of intestinal microbiota. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">FOOD AND CHEMICAL TOXICOLOGY</span> (2024) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/83136487/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Food Science & Technology </span> </div> <h4> <a href="https://www.peeref.com/works/83365090" class="text-dark hover-underline">Acetamiprid induces cardiotoxicity in rats by dysregulating α 7 nAChR and its downstream targets: The ameliorative role of resveratrol</a> </h4> <p class="text-ellipsis-2">Rehab E. Abdelrahman, Mohamed S. Hassan, Ashraf M. Morgan, Marwa A. Ibrahim, Eman I. Hassanen</p> <div class="d-flex mb-3"> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> This study investigated the mechanism of ACP-induced cardiotoxicity and the alleviative effects of RSV. The results showed that ACP exposure caused oxidative stress, histopathological and immunohistochemical changes, and alterations in gene expression, while RSV could alleviate these toxic effects. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">FOOD AND CHEMICAL TOXICOLOGY</span> (2024) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/83365090/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Food Science & Technology </span> </div> <h4> <a href="https://www.peeref.com/works/83195906" class="text-dark hover-underline">Prenatal exposure to bisphenol AF causes toxicities in liver, spleen, and kidney tissues of SD rats</a> </h4> <p class="text-ellipsis-2">Yaxuan Zhu, Xiuxiang Liu, Yijiao Shi, Xiuying Liu, Huaxin Li, Shaoguo Ru, Hua Tian</p> <div class="d-flex mb-3"> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> This study shows that as a replacement for BPA, BPAF has stronger maternal transfer and fetal accumulation capabilities, which may pose risks to the health of offspring. The study found that BPAF accumulated in the liver, spleen, and kidney tissues of the offspring by exposing SD rats to BPAF during pregnancy, and caused adverse effects, including organ damage and changes in gene expression. In addition, dysregulated metabolomics was also found in the spleen. The results of the study provide a comprehensive understanding of the systemic toxicity of BPAF and emphasize the need to re-consider its safety. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">FOOD AND CHEMICAL TOXICOLOGY</span> (2024) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/83195906/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Food Science & Technology </span> </div> <h4> <a href="https://www.peeref.com/works/83110009" class="text-dark hover-underline">Allergenicity assessment of new or modified protein-containing food sources and ingredients</a> </h4> <p class="text-ellipsis-2">R. W. R. Crevel, K. Verhoeckx, K. L. Bogh, N. Buck, A. Chentouf, S. Flanagan, M. Galano, J. A. Garthoff, S. Hazebrouck, R. Yarham, G. Borja, G. Houben</p> <div class="d-flex mb-3"> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> This paper discusses the challenges posed by the development of novel foods, including the difficulties in assessing their allergenicity and the insufficiency of methodological tools. It proposes a comprehensive assessment framework that emphasizes the importance of knowledge and data, and calls for attention to research priorities to fill the gaps. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">FOOD AND CHEMICAL TOXICOLOGY</span> (2024) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/83110009/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Food Science & Technology </span> </div> <h4> <a href="https://www.peeref.com/works/83157577" class="text-dark hover-underline">Preface to the special issue of Food and Chemical Toxicology on New approach methodologies and machine learning in food safety and chemical risk assessment: Development of reproducible, open-source, and user-friendly tools for exposure, toxicokinetic, and toxicity assessments in the 21st century </a> </h4> <p class="text-ellipsis-2">Zhoumeng Lin, Danilo Basili, Wei-Chun Chou</p> <div class="d-flex mb-3"> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> This Special Issue presents the applications of NAMs in toxicology and risk assessment, such as in vitro high-throughput screening and QSAR modeling. These methods can be used in food safety assessment and help to investigate the potential mechanisms of toxicities. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">FOOD AND CHEMICAL TOXICOLOGY</span> (2024) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/83157577/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Food Science & Technology </span> </div> <h4> <a href="https://www.peeref.com/works/83358889" class="text-dark hover-underline">Emamectin benzoate-induced toxicity affects intestinal epithelial integrity involving apoptosis</a> </h4> <p class="text-ellipsis-2">Xingyu Yue, Fengxiang Lin, Shuyan Gui, Sai Zhang, Zongbin Wu, Yuxin Xiang, Tianxiang Xiao, Jinjing Xiao, Haiqun Cao, Yanhong Shi</p> <div class="d-flex mb-3"> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> This study evaluated the intestinal toxicity and pathogenic potential of emamectin benzoate using a Caco-2 cell model, and found that it can damage the intestinal epithelial barrier and induce apoptosis. It also identified key genes and differentially expressed genes related to apoptosis, as well as pathways related to neurodegenerative diseases. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">FOOD AND CHEMICAL TOXICOLOGY</span> (2024) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/83358889/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Review </span> <span class="d-inline-block badge badge-cyan"> Food Science & Technology </span> </div> <h4> <a href="https://www.peeref.com/works/83980000" class="text-dark hover-underline">Recent advances in environmental toxicology: Exploring gene editing, organ-on-a-chip, chimeric animals, and in silico models</a> </h4> <p class="text-ellipsis-2">Yanyi Zhao, Nuoya Yin, Renjun Yang, Francesco Faiola</p> <div class="d-flex mb-3"> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> This review summarizes the limitations of traditional environmental toxicology methods and the application of high-end technologies in environmental toxicology research. The development of high-end technologies provides new opportunities for environmental toxicology research, which can more accurately predict the toxicity of environmental pollutants. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">FOOD AND CHEMICAL TOXICOLOGY</span> (2024) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/83980000/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Review </span> <span class="d-inline-block badge badge-cyan"> Food Science & Technology </span> </div> <h4> <a href="https://www.peeref.com/works/83733674" class="text-dark hover-underline">Oocyte maturation, blastocyst and embryonic development are mediated and enhanced via hormesis</a> </h4> <p class="text-ellipsis-2">Edward J. Calabrese, Peter Pressman, A. Wallace Hayes, Gaurav Dhawan, Rachna Kapoor, Evgenios Agathokleous, Vittorio Calabrese</p> <div class="d-flex mb-3"> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> This study evaluated the effects of various factors on oocyte and early embryonic development, and found that many factors can promote oocyte maturation and blastocyst/embryo development in a hormetic manner, and also enhance the ability of oocytes to prevent damage. This suggests that hormesis-based lifestyles and dietary interventions may help improve fertility and reproductive success, and the study also extends the generality of the hormesis dose response concept. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">FOOD AND CHEMICAL TOXICOLOGY</span> (2024) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/83733674/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Food Science & Technology </span> </div> <h4> <a href="https://www.peeref.com/works/83364910" class="text-dark hover-underline">Health risks associated with mercury intake from rice and rice products</a> </h4> <p class="text-ellipsis-2">Agata Witczak, Monika Rajkowska-Mysliwiec, Kamila Pokorska-Niewiada, Carolina Borja Navarro</p> <div class="d-flex mb-3"> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> This study determined the concentration of total mercury in rice and rice products sold in Poland and assessed the consumer risk. The results showed that the mercury content in rice cakes was the highest, while that in white rice and rice noodles was the lowest, all below the maximum permitted level. The EDI and THQ values of THg and MeHg were both lower than 1, indicating that these foods pose no risk to health. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">FOOD AND CHEMICAL TOXICOLOGY</span> (2024) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/83364910/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Food Science & Technology </span> </div> <h4> <a href="https://www.peeref.com/works/83358822" class="text-dark hover-underline">Hydroxygenkwanin exerts a neuroprotective effect by activating the Nrf2/ ARE signaling pathway</a> </h4> <p class="text-ellipsis-2">Alsiddig Osama, Jun Wu, Qiuying Nie, Zi-Long Song, Linjie Zhang, Jia Gao, Baoxin Zhang</p> <div class="d-flex mb-3"> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> This study investigated the therapeutic effects and mechanisms of hydroxygenkwanin (HGK) on neurodegenerative diseases. The results showed that HGK can protect PC12 cells from oxidative damage by activating the Nrf2/ARE signaling pathway and upregulating endogenous antioxidant proteins. This provides a theoretical basis for the development of HGK as a potential drug for the treatment of oxidative stress-related neuropathologies. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">FOOD AND CHEMICAL TOXICOLOGY</span> (2024) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/83358822/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Food Science & Technology </span> </div> <h4> <a href="https://www.peeref.com/works/83781324" class="text-dark hover-underline">Influence of artificial digestion on characteristics and intestinal cellular effects of micro-, submicro- and nanoplastics</a> </h4> <p class="text-ellipsis-2">Maxi B. Paul, Linda Boehmert, Andreas F. Thuenemann, Katrin Loeschner, Lucas Givelet, Christoph Fahrenson, Albert Braeuning, Holger Sieg</p> <div class="d-flex mb-3"> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> This study investigated the effects of artificial digestion on plastic particles of different materials and sizes, and their cellular effects. The results showed that artificial digestion decreased cellular interaction and increased particle transport, and the polymer, size and surface properties of the particles affected their cellular effects. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">FOOD AND CHEMICAL TOXICOLOGY</span> (2024) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/83781324/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> <div class="my-4 border-bottom"> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Food Science & Technology </span> </div> <h4> <a href="https://www.peeref.com/works/83136226" class="text-dark hover-underline">Maternal diet quality during pregnancy and biomarkers of potentially toxic trace element exposure: Data from the ELFE cohort</a> </h4> <p class="text-ellipsis-2">Courtney Dow, Manik Kadawathagedara, Manel Ghozal, Marie-Aline Charles, Karine Adel-Patient, Clementine Dereumeaux, Blandine de Lauzon-Guillain</p> <div class="d-flex mb-3"> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> This study investigated the association between maternal diet during pregnancy and exposure to potentially toxic trace elements. The results showed that a healthy dietary pattern was associated with higher concentrations of arsenic and mercury, while the relationship between cord blood lead levels and dietary patterns was inconsistent. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">FOOD AND CHEMICAL TOXICOLOGY</span> (2024) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/83136226/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> <div class="my-4 "> <div> <span class="d-inline-block badge badge-blue"> Article </span> <span class="d-inline-block badge badge-cyan"> Food Science & Technology </span> </div> <h4> <a href="https://www.peeref.com/works/83735984" class="text-dark hover-underline">The ameliorative effect of Naringenin on fenamiphos induced hepatotoxicity and nephrotoxicity in a rat model: Oxidative stress, inflammatory markers, biochemical, histopathological, immunohistochemical and electron microscopy study</a> </h4> <p class="text-ellipsis-2">Hatice Karaboduk, Caglar Adiguzel, Fatma Gokce Apaydin, Meltem Uzunhisarcikli, Suna Kalender, Yusuf Kalender</p> <div class="d-flex mb-3"> <div class="p-3 rounded" style="background-color: #e8f3ff;"> <strong>Summary:</strong> This study investigated the toxicity of fenamiphos on the liver and kidney of rats and the protective effect of naringenin. The results showed that fenamiphos could cause oxidative stress and tissue damage, while naringenin could alleviate its toxicity. </div> </div> <div class="d-flex justify-content-between"> <p class="font-weight-bold"> <span class="text-primary">FOOD AND CHEMICAL TOXICOLOGY</span> (2024) </p> <div class="flex-shrink-0"> <a class="btn btn-outline-primary btn-sm" href="https://www.peeref.com/works/83735984/add-to-collection" target="_blank"> <strong>Add to Collection</strong> </a> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div class="modal fade" id="export-citation" tabindex="-1"> <div class="modal-dialog"> <div class="modal-content"> <div class="modal-header"> <button type="button" class="close" data-dismiss="modal"><span>×</span></button> <h4 class="modal-title">Export Citation <b class="text-primary"></b></h4> </div> <div class="modal-body"> <div class="my-3 px-4 f16"> <form action="https://www.peeref.com/works/citation/download" method="GET" target="_blank"> <div 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