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<li id="toc-Timeline" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Timeline"> <div class="vector-toc-text"> 2 Timeline </div> </a> <ul id="toc-Timeline-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Amgen_Foundation" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Amgen_Foundation"> <div class="vector-toc-text"> 3 Amgen Foundation </div> </a> <ul id="toc-Amgen_Foundation-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Acquisitions" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Acquisitions"> <div class="vector-toc-text"> 4 Acquisitions </div> </a> <ul id="toc-Acquisitions-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Products" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Products"> <div class="vector-toc-text"> 5 Products </div> </a> <button aria-controls="toc-Products-sublist" class="cdx-button cdx-button--weight-quiet cdx-button--icon-only vector-toc-toggle"> Toggle Products subsection </button> <ul id="toc-Products-sublist" class="vector-toc-list"> <li id="toc-Products_developed_and_then_sold_off" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Products_developed_and_then_sold_off"> <div class="vector-toc-text"> 5.1 Products developed and then sold off </div> </a> <ul id="toc-Products_developed_and_then_sold_off-sublist" class="vector-toc-list"> </ul> </li> </ul> </li> <li id="toc-Pipeline_and_clinical_trials" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Pipeline_and_clinical_trials"> <div class="vector-toc-text"> 6 Pipeline and clinical trials </div> </a> <ul id="toc-Pipeline_and_clinical_trials-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Carbon_footprint" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Carbon_footprint"> <div class="vector-toc-text"> 7 Carbon footprint </div> </a> <ul id="toc-Carbon_footprint-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Controversies" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Controversies"> <div class="vector-toc-text"> 8 Controversies </div> </a> <ul id="toc-Controversies-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Public-private_engagement" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Public-private_engagement"> <div class="vector-toc-text"> 9 Public-private engagement </div> </a> <button aria-controls="toc-Public-private_engagement-sublist" class="cdx-button cdx-button--weight-quiet cdx-button--icon-only vector-toc-toggle"> Toggle Public-private engagement subsection </button> <ul id="toc-Public-private_engagement-sublist" class="vector-toc-list"> <li id="toc-Academia" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Academia"> <div class="vector-toc-text"> 9.1 Academia </div> </a> <ul id="toc-Academia-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Events_and_conferences" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Events_and_conferences"> <div class="vector-toc-text"> 9.2 Events and conferences </div> </a> <ul id="toc-Events_and_conferences-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Health_care" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Health_care"> <div class="vector-toc-text"> 9.3 Health care </div> </a> <ul id="toc-Health_care-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Media" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Media"> <div class="vector-toc-text"> 9.4 Media </div> </a> <ul id="toc-Media-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Medical_societies" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Medical_societies"> <div class="vector-toc-text"> 9.5 Medical societies </div> </a> <ul id="toc-Medical_societies-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Political_lobbying" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Political_lobbying"> <div class="vector-toc-text"> 9.6 Political lobbying </div> </a> <ul id="toc-Political_lobbying-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Professional_associations" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Professional_associations"> <div class="vector-toc-text"> 9.7 Professional associations </div> </a> <ul id="toc-Professional_associations-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Research_and_development" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Research_and_development"> <div class="vector-toc-text"> 9.8 Research and development </div> </a> <ul id="toc-Research_and_development-sublist" class="vector-toc-list"> </ul> </li> </ul> </li> <li id="toc-Awards_and_recognition" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Awards_and_recognition"> <div class="vector-toc-text"> 10 Awards and recognition </div> </a> <ul id="toc-Awards_and_recognition-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-See_also" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#See_also"> <div class="vector-toc-text"> 11 See also </div> </a> <ul id="toc-See_also-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-References" class="vector-toc-list-item vector-toc-level-1 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Available in 27 languages" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-27" aria-hidden="true" > 27 languages </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-ar mw-list-item"><a href="https://ar.wikipedia.org/wiki/%D8%A3%D9%85%D8%AC%D9%86" title="أمجن – Arabic" lang="ar" hreflang="ar" data-title="أمجن" data-language-autonym="العربية" data-language-local-name="Arabic" class="interlanguage-link-target">العربية</a></li><li class="interlanguage-link interwiki-bg mw-list-item"><a href="https://bg.wikipedia.org/wiki/%D0%90%D0%BC%D0%B4%D0%B6%D0%B5%D0%BD" title="Амджен – Bulgarian" lang="bg" hreflang="bg" data-title="Амджен" data-language-autonym="Български" data-language-local-name="Bulgarian" class="interlanguage-link-target">Български</a></li><li class="interlanguage-link interwiki-da mw-list-item"><a href="https://da.wikipedia.org/wiki/Amgen" title="Amgen – Danish" lang="da" hreflang="da" data-title="Amgen" data-language-autonym="Dansk" data-language-local-name="Danish" class="interlanguage-link-target">Dansk</a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/Amgen" title="Amgen – German" lang="de" hreflang="de" data-title="Amgen" data-language-autonym="Deutsch" data-language-local-name="German" class="interlanguage-link-target">Deutsch</a></li><li class="interlanguage-link interwiki-et mw-list-item"><a href="https://et.wikipedia.org/wiki/Amgen" title="Amgen – Estonian" lang="et" hreflang="et" data-title="Amgen" data-language-autonym="Eesti" data-language-local-name="Estonian" class="interlanguage-link-target">Eesti</a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/Amgen" title="Amgen – Spanish" lang="es" hreflang="es" data-title="Amgen" data-language-autonym="Español" data-language-local-name="Spanish" class="interlanguage-link-target">Español</a></li><li class="interlanguage-link interwiki-eo mw-list-item"><a href="https://eo.wikipedia.org/wiki/Amgen" title="Amgen – Esperanto" lang="eo" hreflang="eo" data-title="Amgen" data-language-autonym="Esperanto" data-language-local-name="Esperanto" class="interlanguage-link-target">Esperanto</a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/%D8%A7%D9%85%DA%98%D9%86" title="امژن – Persian" lang="fa" hreflang="fa" data-title="امژن" data-language-autonym="فارسی" data-language-local-name="Persian" class="interlanguage-link-target">فارسی</a></li><li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/Amgen" title="Amgen – French" lang="fr" hreflang="fr" data-title="Amgen" data-language-autonym="Français" data-language-local-name="French" class="interlanguage-link-target">Français</a></li><li class="interlanguage-link interwiki-ko mw-list-item"><a href="https://ko.wikipedia.org/wiki/%EC%95%94%EC%A0%A0" title="암젠 – Korean" lang="ko" hreflang="ko" data-title="암젠" data-language-autonym="한국어" data-language-local-name="Korean" class="interlanguage-link-target">한국어</a></li><li class="interlanguage-link interwiki-id mw-list-item"><a href="https://id.wikipedia.org/wiki/Amgen" title="Amgen – Indonesian" lang="id" hreflang="id" data-title="Amgen" data-language-autonym="Bahasa Indonesia" data-language-local-name="Indonesian" class="interlanguage-link-target">Bahasa Indonesia</a></li><li class="interlanguage-link interwiki-it mw-list-item"><a href="https://it.wikipedia.org/wiki/Amgen" title="Amgen – Italian" lang="it" hreflang="it" data-title="Amgen" data-language-autonym="Italiano" data-language-local-name="Italian" class="interlanguage-link-target">Italiano</a></li><li class="interlanguage-link interwiki-he mw-list-item"><a href="https://he.wikipedia.org/wiki/%D7%90%D7%9E%D7%92%27%D7%9F" title="אמג'ן – Hebrew" lang="he" hreflang="he" data-title="אמג'ן" data-language-autonym="עברית" data-language-local-name="Hebrew" class="interlanguage-link-target">עברית</a></li><li class="interlanguage-link interwiki-arz mw-list-item"><a href="https://arz.wikipedia.org/wiki/%D8%A7%D9%85%D8%AC%D9%86" title="امجن – Egyptian Arabic" lang="arz" hreflang="arz" data-title="امجن" data-language-autonym="مصرى" data-language-local-name="Egyptian Arabic" class="interlanguage-link-target">مصرى</a></li><li class="interlanguage-link interwiki-ms mw-list-item"><a href="https://ms.wikipedia.org/wiki/Amgen" title="Amgen – Malay" lang="ms" hreflang="ms" data-title="Amgen" data-language-autonym="Bahasa Melayu" data-language-local-name="Malay" class="interlanguage-link-target">Bahasa Melayu</a></li><li class="interlanguage-link interwiki-nl mw-list-item"><a href="https://nl.wikipedia.org/wiki/Amgen" title="Amgen – Dutch" lang="nl" hreflang="nl" data-title="Amgen" data-language-autonym="Nederlands" data-language-local-name="Dutch" class="interlanguage-link-target">Nederlands</a></li><li class="interlanguage-link interwiki-ja mw-list-item"><a href="https://ja.wikipedia.org/wiki/%E3%82%A2%E3%83%A0%E3%82%B8%E3%82%A7%E3%83%B3" title="アムジェン – Japanese" lang="ja" hreflang="ja" data-title="アムジェン" data-language-autonym="日本語" data-language-local-name="Japanese" class="interlanguage-link-target">日本語</a></li><li class="interlanguage-link interwiki-pl mw-list-item"><a href="https://pl.wikipedia.org/wiki/Amgen" title="Amgen – Polish" lang="pl" hreflang="pl" data-title="Amgen" data-language-autonym="Polski" data-language-local-name="Polish" class="interlanguage-link-target">Polski</a></li><li class="interlanguage-link interwiki-pt mw-list-item"><a href="https://pt.wikipedia.org/wiki/Amgen" title="Amgen – Portuguese" lang="pt" hreflang="pt" data-title="Amgen" data-language-autonym="Português" data-language-local-name="Portuguese" class="interlanguage-link-target">Português</a></li><li class="interlanguage-link interwiki-ro mw-list-item"><a href="https://ro.wikipedia.org/wiki/Amgen" title="Amgen – Romanian" lang="ro" hreflang="ro" data-title="Amgen" data-language-autonym="Română" data-language-local-name="Romanian" class="interlanguage-link-target">Română</a></li><li class="interlanguage-link interwiki-ru mw-list-item"><a href="https://ru.wikipedia.org/wiki/Amgen" title="Amgen – Russian" lang="ru" hreflang="ru" data-title="Amgen" data-language-autonym="Русский" data-language-local-name="Russian" class="interlanguage-link-target">Русский</a></li><li class="interlanguage-link interwiki-fi mw-list-item"><a href="https://fi.wikipedia.org/wiki/Amgen" title="Amgen – Finnish" lang="fi" hreflang="fi" data-title="Amgen" data-language-autonym="Suomi" data-language-local-name="Finnish" class="interlanguage-link-target">Suomi</a></li><li class="interlanguage-link interwiki-sv mw-list-item"><a href="https://sv.wikipedia.org/wiki/Amgen" title="Amgen – Swedish" lang="sv" hreflang="sv" data-title="Amgen" data-language-autonym="Svenska" data-language-local-name="Swedish" class="interlanguage-link-target">Svenska</a></li><li class="interlanguage-link interwiki-uk mw-list-item"><a href="https://uk.wikipedia.org/wiki/Amgen" title="Amgen – Ukrainian" lang="uk" hreflang="uk" data-title="Amgen" data-language-autonym="Українська" data-language-local-name="Ukrainian" class="interlanguage-link-target">Українська</a></li><li class="interlanguage-link interwiki-vi mw-list-item"><a href="https://vi.wikipedia.org/wiki/Amgen" title="Amgen – Vietnamese" lang="vi" hreflang="vi" data-title="Amgen" data-language-autonym="Tiếng Việt" data-language-local-name="Vietnamese" class="interlanguage-link-target">Tiếng Việt</a></li><li class="interlanguage-link interwiki-zh-yue mw-list-item"><a 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dir="ltr"><div class="shortdescription nomobile noexcerpt noprint searchaux" style="display:none">American multinational biopharmaceutical company</div> <style data-mw-deduplicate="TemplateStyles:r1251242444">.mw-parser-output .ambox{border:1px solid #a2a9b1;border-left:10px solid #36c;background-color:#fbfbfb;box-sizing:border-box}.mw-parser-output .ambox+link+.ambox,.mw-parser-output .ambox+link+style+.ambox,.mw-parser-output .ambox+link+link+.ambox,.mw-parser-output .ambox+.mw-empty-elt+link+.ambox,.mw-parser-output .ambox+.mw-empty-elt+link+style+.ambox,.mw-parser-output .ambox+.mw-empty-elt+link+link+.ambox{margin-top:-1px}html body.mediawiki .mw-parser-output .ambox.mbox-small-left{margin:4px 1em 4px 0;overflow:hidden;width:238px;border-collapse:collapse;font-size:88%;line-height:1.25em}.mw-parser-output .ambox-speedy{border-left:10px solid #b32424;background-color:#fee7e6}.mw-parser-output .ambox-delete{border-left:10px solid #b32424}.mw-parser-output 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Please help <a class="external text" href="https://en.wikipedia.org/w/index.php?title=Amgen&action=edit">improve it</a> by replacing them with more appropriate <a href="/wiki/Wikipedia:Citing_sources" title="Wikipedia:Citing sources">citations</a> to <a href="/wiki/Wikipedia:Independent_sources" title="Wikipedia:Independent sources">reliable, independent sources</a>. (August 2020) (<a href="/wiki/Help:Maintenance_template_removal" title="Help:Maintenance template removal">Learn how and when to remove this message</a>)</div></td></tr></tbody></table> <style data-mw-deduplicate="TemplateStyles:r1257001546">.mw-parser-output .infobox-subbox{padding:0;border:none;margin:-3px;width:auto;min-width:100%;font-size:100%;clear:none;float:none;background-color:transparent}.mw-parser-output .infobox-3cols-child{margin:auto}.mw-parser-output .infobox .navbar{font-size:100%}@media screen{html.skin-theme-clientpref-night .mw-parser-output .infobox-full-data:not(.notheme)>div:not(.notheme)[style]{background:#1f1f23!important;color:#f8f9fa}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .infobox-full-data:not(.notheme) div:not(.notheme){background:#1f1f23!important;color:#f8f9fa}}@media(min-width:640px){body.skin--responsive .mw-parser-output .infobox-table{display:table!important}body.skin--responsive .mw-parser-output .infobox-table>caption{display:table-caption!important}body.skin--responsive .mw-parser-output .infobox-table>tbody{display:table-row-group}body.skin--responsive .mw-parser-output .infobox-table tr{display:table-row!important}body.skin--responsive .mw-parser-output .infobox-table th,body.skin--responsive .mw-parser-output .infobox-table td{padding-left:inherit;padding-right:inherit}}</style><style data-mw-deduplicate="TemplateStyles:r1242257876">.mw-parser-output .ib-company .infobox-label{padding-right:0.5em}.mw-parser-output .ib-company .infobox-data,.mw-parser-output .ib-company .infobox-below{line-height:1.35em}.mw-parser-output .ib-company-logo img{background-color:#f8f9fa}.mw-parser-output .ib-company-locality,.mw-parser-output .ib-company-country{display:inline}</style><table class="infobox ib-company vcard"><caption class="infobox-title fn org" style="font-size: 125%;">Amgen Inc.</caption><tbody><tr><td colspan="2" class="infobox-image ib-company-logo logo"><a href="/wiki/File:Amgen.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/a/ab/Amgen.svg/250px-Amgen.svg.png" decoding="async" width="250" height="64" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/a/ab/Amgen.svg/375px-Amgen.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/a/ab/Amgen.svg/500px-Amgen.svg.png 2x" data-file-width="167" data-file-height="43" /></a></td></tr><tr><td colspan="2" class="infobox-image ib-company-logo logo"><a href="/wiki/File:Amgenheadquarters.jpg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/3/3e/Amgenheadquarters.jpg/250px-Amgenheadquarters.jpg" decoding="async" width="250" height="176" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/3/3e/Amgenheadquarters.jpg/500px-Amgenheadquarters.jpg 1.5x" data-file-width="4904" data-file-height="3456" /></a><div class="infobox-caption">Headquarters in Thousand Oaks, California</div></td></tr><tr><th scope="row" class="infobox-label">Formerly</th><td class="infobox-data nickname">Applied Molecular Genetics (1980–1983)</td></tr><tr><th scope="row" class="infobox-label">Company type</th><td class="infobox-data category"><a href="/wiki/Public_company" title="Public company">Public</a></td></tr><tr><th scope="row" class="infobox-label"><div style="display: inline-block; line-height: 1.2em; padding: .1em 0;"><a href="/wiki/Ticker_symbol" title="Ticker symbol">Traded as</a></div></th><td class="infobox-data"><style data-mw-deduplicate="TemplateStyles:r1126788409">.mw-parser-output .plainlist ol,.mw-parser-output .plainlist ul{line-height:inherit;list-style:none;margin:0;padding:0}.mw-parser-output .plainlist ol li,.mw-parser-output .plainlist ul li{margin-bottom:0}</style><div class="plainlist"><ul><li><a href="/wiki/Nasdaq" title="Nasdaq">Nasdaq</a>: <a rel="nofollow" class="external text" href="https://www.nasdaq.com/market-activity/stocks/amgn">AMGN</a></li><li><a href="/wiki/Nasdaq-100" title="Nasdaq-100">Nasdaq-100</a> component</li><li><a href="/wiki/DJIA" class="mw-redirect" title="DJIA">DJIA</a> component</li><li><a href="/wiki/S%26P_100" title="S&P 100">S&P 100</a> component</li><li><a href="/wiki/S%26P_500" title="S&P 500">S&P 500</a> component</li></ul></div></td></tr><tr><th scope="row" class="infobox-label"><a href="/wiki/International_Securities_Identification_Number" title="International Securities Identification Number">ISIN</a></th><td class="infobox-data"><a class="external text" href="https://isin.toolforge.org/?language=en&isin=US0311621009">US0311621009</a></td></tr><tr><th scope="row" class="infobox-label">Industry</th><td class="infobox-data category"><a href="/wiki/Biotechnology" title="Biotechnology">Biotechnology</a></td></tr><tr><th scope="row" class="infobox-label">Founded</th><td class="infobox-data">April 8, 1980; 44 years ago (1980-04-08)</td></tr><tr><th scope="row" class="infobox-label">Headquarters</th><td class="infobox-data label"><a href="/wiki/Thousand_Oaks,_California" title="Thousand Oaks, California">Thousand Oaks, California</a>, U.S.</td></tr><tr><th scope="row" class="infobox-label"><div style="display: inline-block; line-height: 1.2em; padding: .1em 0;">Key people</div></th><td class="infobox-data agent"><a href="/wiki/Robert_A._Bradway" title="Robert A. Bradway">Robert A. Bradway</a> (<a href="/wiki/Chairman" class="mw-redirect" title="Chairman">chairman</a>, <a href="/wiki/President_(corporate_title)" title="President (corporate title)">president</a> & <a href="/wiki/Chief_executive_officer" title="Chief executive officer">CEO</a>)</td></tr><tr><th scope="row" class="infobox-label">Products</th><td class="infobox-data"><style data-mw-deduplicate="TemplateStyles:r1129693374">.mw-parser-output .hlist dl,.mw-parser-output .hlist ol,.mw-parser-output .hlist ul{margin:0;padding:0}.mw-parser-output .hlist dd,.mw-parser-output .hlist dt,.mw-parser-output .hlist li{margin:0;display:inline}.mw-parser-output .hlist.inline,.mw-parser-output .hlist.inline dl,.mw-parser-output .hlist.inline ol,.mw-parser-output .hlist.inline ul,.mw-parser-output .hlist dl dl,.mw-parser-output .hlist dl ol,.mw-parser-output .hlist dl ul,.mw-parser-output .hlist ol dl,.mw-parser-output .hlist ol ol,.mw-parser-output .hlist ol ul,.mw-parser-output .hlist ul dl,.mw-parser-output .hlist ul ol,.mw-parser-output .hlist ul ul{display:inline}.mw-parser-output .hlist .mw-empty-li{display:none}.mw-parser-output .hlist dt::after{content:": "}.mw-parser-output .hlist dd::after,.mw-parser-output .hlist li::after{content:" · ";font-weight:bold}.mw-parser-output .hlist dd:last-child::after,.mw-parser-output .hlist dt:last-child::after,.mw-parser-output .hlist li:last-child::after{content:none}.mw-parser-output .hlist dd dd:first-child::before,.mw-parser-output .hlist dd dt:first-child::before,.mw-parser-output .hlist dd li:first-child::before,.mw-parser-output .hlist dt dd:first-child::before,.mw-parser-output .hlist dt dt:first-child::before,.mw-parser-output .hlist dt li:first-child::before,.mw-parser-output .hlist li dd:first-child::before,.mw-parser-output .hlist li dt:first-child::before,.mw-parser-output .hlist li li:first-child::before{content:" (";font-weight:normal}.mw-parser-output .hlist dd dd:last-child::after,.mw-parser-output .hlist dd dt:last-child::after,.mw-parser-output .hlist dd li:last-child::after,.mw-parser-output .hlist dt dd:last-child::after,.mw-parser-output .hlist dt dt:last-child::after,.mw-parser-output .hlist dt li:last-child::after,.mw-parser-output .hlist li dd:last-child::after,.mw-parser-output .hlist li dt:last-child::after,.mw-parser-output .hlist li li:last-child::after{content:")";font-weight:normal}.mw-parser-output .hlist ol{counter-reset:listitem}.mw-parser-output .hlist ol>li{counter-increment:listitem}.mw-parser-output .hlist ol>li::before{content:" "counter(listitem)"\a0 "}.mw-parser-output .hlist dd ol>li:first-child::before,.mw-parser-output .hlist dt ol>li:first-child::before,.mw-parser-output .hlist li ol>li:first-child::before{content:" ("counter(listitem)"\a0 "}</style><div class="hlist"><ul><li><a href="/wiki/Aimovig" class="mw-redirect" title="Aimovig">Aimovig</a></li><li><a href="/wiki/Aranesp" class="mw-redirect" title="Aranesp">Aranesp</a></li><li><a href="/wiki/Blincyto" class="mw-redirect" title="Blincyto">Blincyto</a></li><li><a href="/wiki/Epogen" class="mw-redirect" title="Epogen">Epogen</a></li><li><a href="/wiki/Anakinra" title="Anakinra">Kineret</a></li><li><a href="/wiki/Enbrel" class="mw-redirect" title="Enbrel">Enbrel</a></li><li><a href="/wiki/Kyprolis" class="mw-redirect" title="Kyprolis">Kyprolis</a></li><li><a href="/wiki/Neulasta" class="mw-redirect" title="Neulasta">Neulasta</a></li><li><a href="/wiki/Neupogen" class="mw-redirect" title="Neupogen">Neupogen</a></li><li><a href="/wiki/Nplate" class="mw-redirect" title="Nplate">Nplate</a></li><li><a href="/wiki/Parsabiv" class="mw-redirect" title="Parsabiv">Parsabiv</a></li><li><a href="/wiki/Prolia" class="mw-redirect" title="Prolia">Prolia</a></li><li><a href="/wiki/Repatha" class="mw-redirect" title="Repatha">Repatha</a></li><li><a href="/wiki/Sensipar" class="mw-redirect" title="Sensipar">Sensipar</a>/<a href="/wiki/Mimpara" class="mw-redirect" title="Mimpara">Mimpara</a></li><li><a href="/wiki/Vectibix" class="mw-redirect" title="Vectibix">Vectibix</a></li><li><a href="/wiki/Xgeva" class="mw-redirect" title="Xgeva">Xgeva</a></li></ul></div></td></tr><tr><th scope="row" class="infobox-label">Revenue</th><td class="infobox-data"><img alt="Increase" src="//upload.wikimedia.org/wikipedia/commons/thumb/b/b0/Increase2.svg/20px-Increase2.svg.png" decoding="async" width="11" height="11" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/b/b0/Increase2.svg/40px-Increase2.svg.png 2x" data-file-width="300" data-file-height="300" /> <a href="/wiki/United_States_dollar" title="United States dollar">US$</a>33.4 billion (2024)</td></tr><tr><th scope="row" class="infobox-label"><div style="display: inline-block; line-height: 1.2em; padding: .1em 0;"><a href="/wiki/Earnings_before_interest_and_taxes" title="Earnings before interest and taxes">Operating income</a></div></th><td class="infobox-data"><img alt="Decrease" src="//upload.wikimedia.org/wikipedia/commons/thumb/e/ed/Decrease2.svg/20px-Decrease2.svg.png" decoding="async" width="11" height="11" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/e/ed/Decrease2.svg/40px-Decrease2.svg.png 2x" data-file-width="300" data-file-height="300" /> US$7.26 billion (2024)</td></tr><tr><th scope="row" class="infobox-label"><div style="display: inline-block; line-height: 1.2em; padding: .1em 0;"><a href="/wiki/Net_income" title="Net income">Net income</a></div></th><td class="infobox-data"><img alt="Decrease" src="//upload.wikimedia.org/wikipedia/commons/thumb/e/ed/Decrease2.svg/20px-Decrease2.svg.png" decoding="async" width="11" height="11" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/e/ed/Decrease2.svg/40px-Decrease2.svg.png 2x" data-file-width="300" data-file-height="300" /> US$4.09 billion (2024)</td></tr><tr><th scope="row" class="infobox-label"><a href="/wiki/Asset" title="Asset">Total assets</a></th><td class="infobox-data"><img alt="Decrease" src="//upload.wikimedia.org/wikipedia/commons/thumb/e/ed/Decrease2.svg/20px-Decrease2.svg.png" decoding="async" width="11" height="11" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/e/ed/Decrease2.svg/40px-Decrease2.svg.png 2x" data-file-width="300" data-file-height="300" /> US$91.8 billion (2024)</td></tr><tr><th scope="row" class="infobox-label"><a href="/wiki/Equity_(finance)" title="Equity (finance)">Total equity</a></th><td class="infobox-data"><img alt="Decrease" src="//upload.wikimedia.org/wikipedia/commons/thumb/e/ed/Decrease2.svg/20px-Decrease2.svg.png" decoding="async" width="11" height="11" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/e/ed/Decrease2.svg/40px-Decrease2.svg.png 2x" data-file-width="300" data-file-height="300" /> US$5.88 billion (2024)</td></tr><tr><th scope="row" class="infobox-label"><div style="display: inline-block; line-height: 1.2em; padding: .1em 0;">Number of employees</div></th><td class="infobox-data">28,000 (2024)</td></tr><tr><th scope="row" class="infobox-label">Website</th><td class="infobox-data"><a rel="nofollow" class="external text" href="https://amgen.com/">amgen.com</a></td></tr><tr><td colspan="2" class="infobox-below">Footnotes / references <a href="#cite_note-quickfacts2020-1">[1]</a><a href="#cite_note-2">[2]</a></td></tr></tbody></table> Amgen Inc. (formerly Applied Molecular Genetics Inc.) is an American multinational <a href="/wiki/Biopharmaceutical" title="Biopharmaceutical">biopharmaceutical</a> <a href="/wiki/Corporation" title="Corporation">company</a> headquartered in <a href="/wiki/Thousand_Oaks,_California" title="Thousand Oaks, California">Thousand Oaks, California</a>.<a href="#cite_note-3">[3]</a><a href="#cite_note-4">[4]</a> As one of the world's largest independent <a href="/wiki/Biotechnology" title="Biotechnology">biotechnology</a> companies, Amgen has approximately 24,000 staff in total as of 2022.<a href="#cite_note-Talhelm-5">[5]</a> The name "AMGen" is a <a href="/wiki/Portmanteau" class="mw-redirect" title="Portmanteau">portmanteau</a> of the company's original name, Applied Molecular Genetics, which became the official name of the company in 1983 (three years after incorporation and coincident with its <a href="/wiki/Initial_public_offering" title="Initial public offering">initial public offering</a>). The company is listed on the Nasdaq Global Select Market under the ticker symbol "AMGN", as well as a component of the <a href="/wiki/Nasdaq-100" title="Nasdaq-100">Nasdaq-100</a>, the <a href="/wiki/Dow_Jones_Industrial_Average" title="Dow Jones Industrial Average">Dow Jones Industrial Average</a>, and the <a href="/wiki/S%26P_100" title="S&P 100">S&P 100</a> and <a href="/wiki/S%26P_500" title="S&P 500">500</a> indices. <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="History">History</h2>[<a href="/w/index.php?title=Amgen&action=edit&section=1" title="Edit section: History">edit</a>]</div> <figure class="mw-default-size mw-halign-right" typeof="mw:File/Thumb"><a href="/wiki/File:AMGenelogo.jpg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/en/b/b7/AMGenelogo.jpg" decoding="async" width="179" height="150" class="mw-file-element" data-file-width="179" data-file-height="150" /></a><figcaption>AMGen corporate logo, 1983</figcaption></figure> <figure class="mw-default-size" typeof="mw:File/Thumb"><a href="/wiki/File:Macri_Amgen.jpg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/a/ad/Macri_Amgen.jpg/250px-Macri_Amgen.jpg" decoding="async" width="220" height="202" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/a/ad/Macri_Amgen.jpg/330px-Macri_Amgen.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/a/ad/Macri_Amgen.jpg/500px-Macri_Amgen.jpg 2x" data-file-width="1920" data-file-height="1764" /></a><figcaption>Argentine president <a href="/wiki/Mauricio_Macri" title="Mauricio Macri">Mauricio Macri</a> meets with heads of Amgen, in 2018.</figcaption></figure> Amgen was established in Thousand Oaks in 1980, as Applied Molecular Genetics.<a href="#cite_note-6">[6]</a><a href="#cite_note-Baker,_Pam_2002_Page_37-7">[7]</a> Amgen was backed by a small group of venture capitalists, and its early focus was on <a href="/wiki/Recombinant_DNA" title="Recombinant DNA">recombinant DNA</a> technology and recombinant human <a href="/wiki/Insulin" title="Insulin">insulin</a>.<a href="#cite_note-Walsh-8">[8]</a> Its initial scientific advisory board consisted of <a href="/wiki/Norman_Davidson_(biologist)" title="Norman Davidson (biologist)">Norman Davidson</a>, <a href="/wiki/Leroy_Hood" title="Leroy Hood">Leroy Hood</a>, <a href="/wiki/Arnold_Berk" title="Arnold Berk">Arnold Berk</a>, <a href="/wiki/John_Carbon" title="John Carbon">John Carbon</a>, <a href="/wiki/Robert_Schimke" title="Robert Schimke">Robert Schimke</a>, <a href="/wiki/Arno_Motulsky" title="Arno Motulsky">Arno Motulsky</a>, <a href="/wiki/Marvin_H._Caruthers" title="Marvin H. Caruthers">Marvin H. Caruthers</a>, and Dave Gibson.<a href="#cite_note-9">[9]</a> In October 1980, Amgen named <a href="/wiki/George_Rathmann" title="George Rathmann">George Rathmann</a> its first president and chief executive officer.<a href="#cite_note-Walsh-8">[8]</a> On June 17, 1983, Amgen went public, selling two million <a href="/wiki/Common_shares" class="mw-redirect" title="Common shares">common shares</a> and raising nearly $40 million.<a href="#cite_note-10">[10]</a><a href="#cite_note-11">[11]</a><a href="#cite_note-12">[12]</a> That same year, after more than two years of work, an Amgen research team led by <a href="/wiki/Fu-Kuen_Lin" title="Fu-Kuen Lin">Fu-Kuen Lin</a> had a breakthrough in finding and cloning the <a href="/wiki/Erythropoietin" title="Erythropoietin">erythropoietin</a> gene, a protein created in the kidney that stimulates <a href="/wiki/Red_blood_cell" title="Red blood cell">red blood cell</a> production. Lin's team created what would become Epogen (<a href="/wiki/Epoetin_alfa" title="Epoetin alfa">epoetin alfa</a>).<a href="#cite_note-13">[13]</a><a href="#cite_note-Kim-14">[14]</a> In 1985, Amgen researcher Larry Souza and his team cloned <a href="/wiki/Granulocyte_colony-stimulating_factor" title="Granulocyte colony-stimulating factor">granulocyte colony-stimulating factor</a> (G-CSF), leading to the development of Neupogen (<a href="/wiki/Filgrastim" title="Filgrastim">filgrastim</a>).<a href="#cite_note-Kim-14">[14]</a><a href="#cite_note-15">[15]</a><a href="#cite_note-16">[16]</a> In October 1988, <a href="/wiki/Gordon_Binder" title="Gordon Binder">Gordon Binder</a> was named CEO, succeeding George Rathmann.<a href="#cite_note-17">[17]</a> The following year, in 1989, Amgen received approval for the first recombinant human erythropoetin product, Epogen (<a href="/wiki/Epoetin_alfa" title="Epoetin alfa">epoetin alfa</a>).<a href="#cite_note-auto-18">[18]</a><a href="#cite_note-19">[19]</a> In February 1991, Amgen received FDA approval for Neupogen for the prevention of infections in patients whose immune systems are suppressed due to cancer chemotherapy.<a href="#cite_note-20">[20]</a><a href="#cite_note-21">[21]</a> Amgen opened a new manufacturing facility in <a href="/wiki/Puerto_Rico" title="Puerto Rico">Puerto Rico</a>, in March 1993, which later became the company's flagship manufacturing site.<a href="#cite_note-22">[22]</a><a href="#cite_note-23">[23]</a> In 1994, Amgen became the fifth company to receive the <a href="/wiki/United_States_Department_of_Commerce" title="United States Department of Commerce">U.S. Department of Commerce</a>'s <a href="/wiki/National_Medal_of_Technology_and_Innovation" title="National Medal of Technology and Innovation">National Medal of Technology and Innovation</a>, in recognition of its work developing medicines to improve quality of life for kidney and cancer patients.<a href="#cite_note-24">[24]</a> Also around this time, Amgen researcher Steve Elliott and his team added more sugar molecules to erythropoietin, causing it to remain in the body longer. This led to the development of Aranesp (<a href="/wiki/Darbepoetin_alfa" title="Darbepoetin alfa">darbepoetin alfa</a>).<a href="#cite_note-25">[25]</a> <div class="mw-heading mw-heading3"><h3 id="2000-2014">2000-2014</h3>[<a href="/w/index.php?title=Amgen&action=edit&section=2" title="Edit section: 2000-2014">edit</a>]</div> Binder was succeeded as CEO by <a href="/wiki/Kevin_W._Sharer" title="Kevin W. Sharer">Kevin W. Sharer</a> in 2000.<a href="#cite_note-26">[26]</a> Robert A. Bradway became Amgen's president and chief executive officer in May 2012, following Sharer's retirement.<a href="#cite_note-Amgen-May-2012-8-K-27">[27]</a> In March 2011, Amgen acquired a manufacturing facility near Dublin, Ireland, in March.<a href="#cite_note-28">[28]</a> Amgen also opened an affiliate in China in 2013.<a href="#cite_note-29">[29]</a><a href="#cite_note-30">[30]</a> In November 2014 the company announced it was halting all trials of <a href="/wiki/Rilotumumab" title="Rilotumumab">rilotumumab</a> in advanced <a href="/wiki/Gastric_cancer" class="mw-redirect" title="Gastric cancer">gastric cancer</a> patients after one of the trials found more deaths in those who took the compound with chemotherapy, than those without.<a href="#cite_note-31">[31]</a> Later in the same week, the company in conjunction with <a href="/wiki/AstraZeneca" title="AstraZeneca">AstraZeneca</a> reported positive results for <a href="/wiki/Brodalumab" title="Brodalumab">brodalumab</a> in a Phase III trial comparing the compound with <a href="/wiki/Ustekinumab" title="Ustekinumab">ustekinumab</a> and a <a href="/wiki/Placebo" title="Placebo">placebo</a> in treating <a href="/wiki/Psoriasis" title="Psoriasis">psoriasis</a>.<a href="#cite_note-32">[32]</a> In the same month, construction was completed on Amgen's next-generation biomanufacturing facility in Singapore.<a href="#cite_note-33">[33]</a> Blincyto (<a href="/wiki/Blinatumomab" title="Blinatumomab">blinatumomab</a>) was approved by the FDA in December of that year.<a href="#cite_note-34">[34]</a><a href="#cite_note-35">[35]</a> Amgen's Thousand Oaks staff in 2022 numbered approximately 5,000<a href="#cite_note-36">[36]</a> (8.5% of total city employment)<a href="#cite_note-37">[37]</a> and included hundreds of scientists, making Amgen the largest employer in <a href="/wiki/Ventura_County,_California" title="Ventura County, California">Ventura County</a>.<a href="#cite_note-Baker,_Pam_2002_Page_37-7">[7]</a><a href="#cite_note-38">[38]</a> <div class="mw-heading mw-heading2"><h2 id="Timeline">Timeline</h2>[<a href="/w/index.php?title=Amgen&action=edit&section=3" title="Edit section: Timeline">edit</a>]</div> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1251242444" /><table class="box-Prose plainlinks metadata ambox ambox-style ambox-Prose" role="presentation"><tbody><tr><td class="mbox-image"><div class="mbox-image-div"><img alt="" src="//upload.wikimedia.org/wikipedia/en/thumb/f/f2/Edit-clear.svg/40px-Edit-clear.svg.png" decoding="async" width="40" height="40" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/f/f2/Edit-clear.svg/60px-Edit-clear.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/f/f2/Edit-clear.svg/80px-Edit-clear.svg.png 2x" data-file-width="48" data-file-height="48" /></div></td><td class="mbox-text"><div class="mbox-text-span">This article is in <a href="/wiki/MOS:LIST" class="mw-redirect" title="MOS:LIST">list</a> format but may read better as <a href="/wiki/MOS:PROSE" class="mw-redirect" title="MOS:PROSE">prose</a>. You can help by <a class="external text" href="https://en.wikipedia.org/w/index.php?title=Amgen&action=edit">converting this article</a>, if appropriate. <a href="/wiki/Help:Editing" title="Help:Editing">Editing help</a> is available. (October 2024)</div></td></tr></tbody></table> <ul><li>1984: In June, Amgen and Kirin formed a joint venture giving Kirin the rights to Epogen in Japan.<a href="#cite_note-39">[39]</a><a href="#cite_note-40">[40]</a></li> <li>2002: In July, Amgen acquired Immunex, the developer of Enbrel (etanercept).<a href="#cite_note-41">[41]</a></li> <li>2004: Also, Amgen acquired Tularik, another biotechnology company, expanding the company's research and development pipeline.<a href="#cite_note-42">[42]</a><a href="#cite_note-43">[43]</a></li> <li>2006: In April, Amgen acquired Abgenix, the developer of Vectibix (<a href="/wiki/Panitumumab" title="Panitumumab">panitumumab</a>), a treatment developed for certain patients with metastatic <a href="/wiki/Colorectal_cancer" title="Colorectal cancer">colorectal cancer</a>.<a href="#cite_note-44">[44]</a><a href="#cite_note-45">[45]</a></li> <li>2010: On June 6, 2010, Amgen received <a href="/wiki/Food_and_Drug_Administration" title="Food and Drug Administration">FDA</a> approval for Prolia, a protein drug for the treatment of post-menopausal osteoporosis.<a href="#cite_note-46">[46]</a> In clinical trials, Prolia reduced the rate of vertebral fractures by 61% and the risk of hip fractures by 40%.<a href="#cite_note-47">[47]</a> In November 2010 the <a href="/wiki/Food_and_Drug_Administration" title="Food and Drug Administration">FDA</a> approved Xgeva for the prevention of complications of bone metastases in patients with solid tumors.<a href="#cite_note-48">[48]</a> The clinical trials primarily enrolled patients with breast or prostate cancer.</li> <li>2011: In May, Amgen acquired BioVex,<a href="#cite_note-49">[49]</a><a href="#cite_note-50">[50]</a> developer of Imlygic (<a href="/wiki/Talimogene_laherparepvec" title="Talimogene laherparepvec">talimogene laherparepvec</a>).<a href="#cite_note-51">[51]</a> In December, Amgen and <a href="/wiki/Watson_Pharmaceuticals" class="mw-redirect" title="Watson Pharmaceuticals">Watson Pharmaceuticals</a> announced a collaboration to develop and commercialize several <a href="/wiki/Biosimilar" title="Biosimilar">biosimilar</a> medicines worldwide.<a href="#cite_note-52">[52]</a><a href="#cite_note-53">[53]</a></li> <li>2012: Amgen acquired Micromet, a company focused on <a href="/wiki/Bi-specific_T-cell_engager" title="Bi-specific T-cell engager">BiTE</a> technology.<a href="#cite_note-54">[54]</a><a href="#cite_note-55">[55]</a></li> <li>2013: Lawmakers inserted text into the fiscal cliff bill that would allow the drugmaker to sell a class of drugs that includes Sensipar without government controls for an additional two years. The New York Times estimated that the paragraph in the fiscal cliff bill will cost taxpayers an estimated $500 million<a href="#cite_note-56">[56]</a> but other assessments concluded that the change would protect seniors in rural areas and reduce overall Medicare spending.<a href="#cite_note-57">[57]</a><a href="#cite_note-58">[58]</a> In May, Kevin Sharer retired, and Robert Bradway, formerly Amgen's president and chief operating officer, became CEO.<a href="#cite_note-59">[59]</a> In June, Amgen acquired Turkish company Mustafa Nevzat Pharmaceuticals, expanding Amgen's presence in Turkey and nearby areas.<a href="#cite_note-60">[60]</a> In July, Amgen acquired KAI Pharmaceuticals, developer of Parsabiv (<a href="/wiki/Etelcalcetide" title="Etelcalcetide">etelcalcetide</a>).<a href="#cite_note-61">[61]</a><a href="#cite_note-62">[62]</a> Amgen acquired Iceland-based <a href="/wiki/DeCODE_genetics" title="DeCODE genetics">deCODE Genetics</a> in December.<a href="#cite_note-63">[63]</a></li> <li>2013: In October, Amgen acquired <a href="/wiki/Onyx_Pharmaceuticals" title="Onyx Pharmaceuticals">Onyx Pharmaceuticals</a>, developer of Kyprolis (<a href="/wiki/Carfilzomib" title="Carfilzomib">carfilzomib</a>).<a href="#cite_note-64">[64]</a></li> <li>2015: In March, the company announced it would license its Phase II candidate drug <a href="/w/index.php?title=AMG_714&action=edit&redlink=1" class="new" title="AMG 714 (page does not exist)">AMG 714</a> to developer <a href="/w/index.php?title=Celimmune&action=edit&redlink=1" class="new" title="Celimmune (page does not exist)">Celimmune</a> who plan to develop the anti-IL-15 <a href="/wiki/Monoclonal_antibody" title="Monoclonal antibody">monoclonal antibody</a> for treatment against diet nonresponsive <a href="/wiki/Celiac_disease" class="mw-redirect" title="Celiac disease">celiac disease</a> and refractory celiac disease.<a href="#cite_note-65">[65]</a></li> <li>2015: Repatha (<a href="/wiki/Evolocumab" title="Evolocumab">evolocumab</a>) was approved by the FDA in August.<a href="#cite_note-66">[66]</a> In September the company announced it would acquire Dezima Pharma for more than $1.55 billion.<a href="#cite_note-genengnews.com-67">[67]</a><a href="#cite_note-68">[68]</a> The same day the company announced a collaboration with Xencor on 6 early stage immuno-oncology and inflammation programmes. As part of the deal Amgen will pay $45 million upfront, with the deal being worth up to another $1.7 billion.<a href="#cite_note-69">[69]</a><a href="#cite_note-70">[70]</a> In October, the FDA approved Imlygic.<a href="#cite_note-71">[71]</a></li> <li>2016: In September, the company announced it would purchase the rights to <a href="/wiki/Boehringer_Ingelheim" title="Boehringer Ingelheim">Boehringer Ingelheims</a> Phase I bispecific T-cell engager compound (BI 836909, now AMG 420) for use in the treatment of <a href="/wiki/Multiple_myeloma" title="Multiple myeloma">multiple myeloma</a>.<a href="#cite_note-72">[72]</a> Also in September, the FDA approved Amjevita (<a href="/wiki/Adalimumab" title="Adalimumab">adalimumab</a>-atto).<a href="#cite_note-Staton-73">[73]</a></li> <li>2017: The FDA approved Parsabiv in February<a href="#cite_note-74">[74]</a> and Mvasi (<a href="/wiki/Bevacizumab" title="Bevacizumab">bevacizumab</a>-awwb) in September.<a href="#cite_note-Mvasi_approval-75">[75]</a></li> <li>2018:Amgen began constructing a next-generation <a href="/wiki/Biomanufacturing" title="Biomanufacturing">biomanufacturing</a> plant at its <a href="/wiki/West_Greenwich,_Rhode_Island" title="West Greenwich, Rhode Island">West Greenwich, Rhode Island</a>, campus in July.<a href="#cite_note-76">[76]</a></li> <li>2019: In January, Evenity (<a href="/wiki/Romosozumab" title="Romosozumab">romosozumab</a>) received approval in Japan,<a href="#cite_note-77">[77]</a><a href="#cite_note-78">[78]</a> followed by FDA approval in April.<a href="#cite_note-79">[79]</a> In June, Kanjinti (<a href="/wiki/Trastuzumab" title="Trastuzumab">trastuzumab</a>-anns) was approved by the FDA.<a href="#cite_note-Kanjinti_approval-80">[80]</a> Amgen announced it would acquire Nuevolution AB for 1.61 billion Swedish crowns ($166.8 million) to enhance its drug discovery capabilities.<a href="#cite_note-81">[81]</a> In August the company announced it would acquire the <a href="/wiki/Otezla" class="mw-redirect" title="Otezla">Otezla</a> drug programme from <a href="/wiki/Celgene" title="Celgene">Celgene</a> for $13.4 billion, as part of Celgene and <a href="/wiki/Bristol-Myers_Squibb" class="mw-redirect" title="Bristol-Myers Squibb">Bristol-Myers Squibbs</a> merger deal.<a href="#cite_note-82">[82]</a><a href="#cite_note-83">[83]</a> In October, Amgen announced it would be acquiring a 20.5% stake in the <a href="/wiki/Beijing" title="Beijing">Beijing</a>-based BeiGene for $2.7 billion.<a href="#cite_note-84">[84]</a> In November, Amgen awarded a $2 million grant to the <a href="/wiki/CDC_Foundation" class="mw-redirect" title="CDC Foundation">CDC Foundation</a> to launch the latter's EmPOWERED Health Program, promoting patient engagement in decision making for their cancer treatment.<a href="#cite_note-85">[85]</a> In December, the FDA approved Avsola (<a href="/wiki/Infliximab" title="Infliximab">infliximab</a>-axxq).<a href="#cite_note-86">[86]</a></li> <li>2020: In April, Amgen established Amgen K.K. as the company's wholly-owned affiliate in Japan.<a href="#cite_note-87">[87]</a><a href="#cite_note-88">[88]</a> Amgen announced in July that the <a href="/wiki/United_States_Court_of_Appeals_for_the_Federal_Circuit" title="United States Court of Appeals for the Federal Circuit">United States Court of Appeals for the Federal Circuit</a> had upheld the validity of two Amgen patents that described and claimed Enbrel and methods for making it. The appellate court affirmed an August 2019 decision by the <a href="/wiki/United_States_District_Court_for_the_District_of_New_Jersey" title="United States District Court for the District of New Jersey">United States District Court for the District of New Jersey</a> and rejected <a href="/wiki/Sandoz" title="Sandoz">Sandoz</a>'s attempt to invalidate the patents on Enbrel.<a href="#cite_note-89">[89]</a> Amgen joined the <a href="/wiki/Dow_Jones_Industrial_Average" title="Dow Jones Industrial Average">Dow Jones Industrial Average</a> on August 24, 2020.<a href="#cite_note-90">[90]</a> In September, Amgen and <a href="/wiki/Eli_Lilly_and_Company" title="Eli Lilly and Company">Eli Lilly and Company</a> announced a global manufacturing collaboration for <a href="/wiki/COVID-19" title="COVID-19">COVID-19</a> antibody therapies.<a href="#cite_note-91">[91]</a> On December 10, Amgen announced that it joined OneTen, a coalition of large employers that aims to hire and advance one million black Americans over the next ten years.<a href="#cite_note-92">[92]</a> Later that month, the FDA approved Riabni (<a href="/wiki/Rituximab" title="Rituximab">rituximab</a>-arrx), a biosimilar to Rituxan.<a href="#cite_note-Riabni_approval-93">[93]</a></li> <li>2021: In March, the company announced it would acquire Five Prime Therapeutics and its lead candidate, <a href="/w/index.php?title=Bemarituzumab&action=edit&redlink=1" class="new" title="Bemarituzumab (page does not exist)">bemarituzumab</a>, for $1.9 billion.<a href="#cite_note-94">[94]</a><a href="#cite_note-95">[95]</a><a href="#cite_note-96">[96]</a> In the same month, Amgen acquired Rodeo Therapeutics for $720 million.<a href="#cite_note-97">[97]</a><a href="#cite_note-98">[98]</a> The FDA approved Amgen's <a href="/wiki/Sotorasib" title="Sotorasib">Lumakras</a> in May for treatment of patients with KRAS-G12C-mutated non-small cell lung cancer.<a href="#cite_note-Lumakras_approval-99">[99]</a> In June, Amgen and <a href="/wiki/Kyowa_Kirin" title="Kyowa Kirin">Kyowa Kirin</a> announced joint plans to develop and commercialize a treatment for <a href="/wiki/Atopic_dermatitis" title="Atopic dermatitis">atopic dermatitis</a>.<a href="#cite_note-100">[100]</a> In July, Amgen acquired Teneobio for $900 million.<a href="#cite_note-101">[101]</a> In October, Amgen and Neumora Therapeutics announced a research and development collaboration focused on novel precision therapies for certain brain diseases.<a href="#cite_note-102">[102]</a><a href="#cite_note-103">[103]</a> Amgen began construction on a new biomanufacturing plant in <a href="/wiki/New_Albany,_Ohio" title="New Albany, Ohio">New Albany, Ohio</a>, in November.<a href="#cite_note-104">[104]</a> In December, the FDA approved Amgen and AstraZeneca's Tezspire (<a href="/wiki/Tezepelumab" title="Tezepelumab">tezepelumab</a>) for severe <a href="/wiki/Asthma" title="Asthma">asthma</a>.<a href="#cite_note-Dunleavy-105">[105]</a> The FDA also approved Amgen's Otezla for adults with plaque <a href="/wiki/Psoriasis" title="Psoriasis">psoriasis</a> of any severity level.<a href="#cite_note-106">[106]</a></li> <li>2022: In January, Amgen announced a research collaboration with Generate Biomedicines across multiple modalities and several therapeutic areas for up to $1.9 billion.<a href="#cite_note-107">[107]</a><a href="#cite_note-108">[108]</a> The company also launched a multi-target collaboration with <a href="/wiki/Arrakis_Therapeutics" title="Arrakis Therapeutics">Arrakis Therapeutics</a> to identify novel targeted RNA degrader therapeutics.<a href="#cite_note-109">[109]</a><a href="#cite_note-110">[110]</a> The next month, Amgen entered a multi-year collaboration with Plexium to discover novel targeted protein degradation therapies.<a href="#cite_note-111">[111]</a><a href="#cite_note-112">[112]</a> Also in February, Amgen issued its first <a href="/wiki/Green_bond" title="Green bond">green bond</a> to fund various environmentally friendly initiatives across the company.<a href="#cite_note-113">[113]</a><a href="#cite_note-114">[114]</a> The company broke ground on a new manufacturing facility in <a href="/wiki/Holly_Springs,_North_Carolina" title="Holly Springs, North Carolina">Holly Springs, North Carolina</a>, in March.<a href="#cite_note-115">[115]</a><a href="#cite_note-116">[116]</a> In August, the company agreed to acquire ChemoCentryx for $3.7 billion in an all-cash deal.<a href="#cite_note-117">[117]</a> ChemoCentryx is the maker of <a href="/wiki/Tavneos" class="mw-redirect" title="Tavneos">Tavneos</a>—a drug treatment for rare diseases called anti-neutrophil cytoplasmic autoantibody-associated <a href="/wiki/Vasculitis" title="Vasculitis">vasculitis</a>—which was approved last year.<a href="#cite_note-118">[118]</a> In December, the company announced it would acquire <a href="/wiki/Horizon_Therapeutics" title="Horizon Therapeutics">Horizon Therapeutics</a> for $27.8 billion ($116.50 in cash for each Horizon share, a 20% premium) expanding its rare disease treatments.<a href="#cite_note-119">[119]</a></li> <li>2023: Amgen completed the acquisition of <a href="/wiki/Horizon_Therapeutics" title="Horizon Therapeutics">Horizon Therapeutics</a> in October 2023.<a href="#cite_note-120">[120]</a> In December, announced plans to use artificial intelligence in partnership with Amazon Web Services to help discover and create medicines.<a href="#cite_note-:1-121">[121]</a> Amgen will use Amazon's SageMaker machine learning service to help with the manufacturing process.<a href="#cite_note-:1-121">[121]</a> That same month, it was confirmed that Amgen would sponsor the 2024 Irish Open as the title sponsor.<a href="#cite_note-122">[122]</a></li></ul> <div class="mw-heading mw-heading2"><h2 id="Amgen_Foundation">Amgen Foundation</h2>[<a href="/w/index.php?title=Amgen&action=edit&section=4" title="Edit section: Amgen Foundation">edit</a>]</div> In October 2017, the Amgen Foundation pledged $3 million to <a href="/wiki/Khan_Academy" title="Khan Academy">Khan Academy</a> to support the development of free online biology lessons.<a href="#cite_note-123">[123]</a><a href="#cite_note-124">[124]</a> In July 2020, Amgen granted an additional $3 million Khan Academy to support educational equity and science learning.<a href="#cite_note-125">[125]</a><a href="#cite_note-126">[126]</a> In January 2020, the Amgen Foundation and <a href="/wiki/Harvard_University" title="Harvard University">Harvard University</a> debuted LabXchange, a free online science education platform.<a href="#cite_note-127">[127]</a><a href="#cite_note-128">[128]</a> Amgen and the Amgen Foundation announced a commitment of up to $12.5 million to support COVID-19 relief efforts in March.<a href="#cite_note-129">[129]</a> <div class="mw-heading mw-heading2"><h2 id="Acquisitions">Acquisitions</h2>[<a href="/w/index.php?title=Amgen&action=edit&section=5" title="Edit section: Acquisitions">edit</a>]</div> <style data-mw-deduplicate="TemplateStyles:r1214851843">.mw-parser-output .hidden-begin{box-sizing:border-box;width:100%;padding:5px;border:none;font-size:95%}.mw-parser-output .hidden-title{font-weight:bold;line-height:1.6;text-align:left}.mw-parser-output .hidden-content{text-align:left}@media all and (max-width:500px){.mw-parser-output .hidden-begin{width:auto!important;clear:none!important;float:none!important}}</style><div class="hidden-begin mw-collapsible mw-collapsible-leftside-toggle mw-collapsed" style=""><div class="hidden-title skin-nightmode-reset-color" style="background:white;">The following is an illustration of the company's major mergers and acquisitions and historical predecessors (this is not a comprehensive list):</div><div class="hidden-content mw-collapsible-content" style=""> <style data-mw-deduplicate="TemplateStyles:r1116488514">.mw-parser-output .treeview ul{padding:0;margin:0}.mw-parser-output .treeview li{padding:0;margin:0;list-style-type:none;list-style-image:none}.mw-parser-output .treeview li li{background:url("https://upload.wikimedia.org/wikipedia/commons/f/f2/Treeview-grey-line.png")no-repeat 0 -2981px;padding-left:21px;text-indent:0.3em}.mw-parser-output .treeview li li:last-child{background-position:0 -5971px}.mw-parser-output .treeview li.emptyline>ul>.mw-empty-elt:first-child+.emptyline,.mw-parser-output .treeview li.emptyline>ul>li:first-child{background-position:0 9px}</style><div class="treeview"> <ul><li>Amgen (Founded 1983 as Applied Molecular Genetics) <ul><li>Synergen Inc (Acq 1994)<a href="#cite_note-130">[130]</a></li> <li>Kinetix Pharmaceuticals Inc (Acq 2000)<a href="#cite_note-131">[131]</a></li> <li>Immunex Corporation (Acq 2002)</li> <li>Tularik Inc (Acq 2004)</li> <li>Abgenix Inc (Acq 2006)</li> <li>Avidia Inc (Acq 2006)<a href="#cite_note-132">[132]</a></li> <li>Alantos Pharmaceuticals (Acq 2007)<a href="#cite_note-133">[133]</a></li> <li>Ilypsa Inc (Acq 2007)<a href="#cite_note-134">[134]</a></li> <li>BioVex Group Inc (Acq 2011)</li> <li>Micromet Inc (Acq 2012)</li> <li>Mustafa Nevzat İlaç (Acq 2012)</li> <li>KAI Pharmaceuticals (Acq 2012)</li> <li><a href="/wiki/DeCODE_genetics" title="DeCODE genetics">deCODE genetics</a> (Acq 2012)</li> <li><a href="/wiki/Onyx_Pharmaceuticals" title="Onyx Pharmaceuticals">Onyx Pharmaceuticals</a> (Acq 2013)</li> <li>NextCODE genetics (Spun off 2013)</li> <li>Dezima Pharma (Acq 2015)</li> <li>Catherex (Acq 2015)<a href="#cite_note-135">[135]</a></li> <li>Nuevolution AB (Acq 2019)</li> <li>Otezla (<a href="/wiki/Apremilast" title="Apremilast">apremilast</a>) (Acq 2019)<a href="#cite_note-136">[136]</a></li> <li>Five Prime Therapeutics (Acq 2021)<a href="#cite_note-137">[137]</a></li> <li>Rodeo Therapeutics Corporation (Acq 2021)<a href="#cite_note-138">[138]</a></li> <li>Teneobio (Acq 2021)</li> <li>ChemoCentryx (Acq 2022)<a href="#cite_note-139">[139]</a></li> <li><a href="/wiki/Horizon_Therapeutics" title="Horizon Therapeutics">Horizon Therapeutics</a> (Acq 2023) <ul><li>Vidara Therapeutics International (Acq 2014)</li> <li>Hyperion Therapeutics (Acq 2015)</li> <li>Crealta Holdings (Acq 2015)</li> <li>Raptor Pharmaceutical (Acq 2016)</li> <li>River Vision Development Corp. (Acq 2017)</li> <li>Viela Bio Inc (Acq 2021)<a href="#cite_note-140">[140]</a></li></ul></li></ul></li></ul> </div> </div></div> <div class="mw-heading mw-heading2"><h2 id="Products">Products</h2>[<a href="/w/index.php?title=Amgen&action=edit&section=6" title="Edit section: Products">edit</a>]</div> Amgen's <a href="/wiki/Approved_drug" title="Approved drug">approved drugs</a> or therapeutic biologicals include: <ul><li>Aimovig (<a href="/wiki/Erenumab-aooe" class="mw-redirect" title="Erenumab-aooe">erenumab-aooe</a>) for <a href="/wiki/Migraine_headaches" class="mw-redirect" title="Migraine headaches">migraine headaches</a> (FDA approved May 2018)<a href="#cite_note-141">[141]</a></li> <li>Amjevita (<a href="/wiki/Adalimumab" title="Adalimumab">adalimumab</a>)<a href="#cite_note-Staton-73">[73]</a> (FDA approved September 2016)</li> <li>Aranesp (<a href="/wiki/Darbepoetin_alfa" title="Darbepoetin alfa">darbepoetin alfa</a>) for <a href="/wiki/Anemia" title="Anemia">anemia</a> (FDA approval in September 2001)<a href="#cite_note-142">[142]</a></li> <li>Blincyto (<a href="/wiki/Blinatumomab" title="Blinatumomab">blinatumomab</a> for the treatment of <a href="/wiki/Acute_lymphoblastic_leukemia" title="Acute lymphoblastic leukemia">acute lymphoblastic leukemia</a>)<a href="#cite_note-143">[143]</a></li> <li>Corlanor (<a href="/wiki/Ivabradine" title="Ivabradine">ivabradine</a>)</li> <li>Enbrel (<a href="/wiki/Etanercept" title="Etanercept">etanercept</a>) for various forms of <a href="/wiki/Arthritis" title="Arthritis">arthritis</a></li> <li>Epogen (<a href="/wiki/Erythropoietin" title="Erythropoietin">erythropoietin</a>) for <a href="/wiki/Anemia" title="Anemia">anemia</a></li> <li>Evenity (<a href="/wiki/Romosozumab-aqqg" class="mw-redirect" title="Romosozumab-aqqg">romosozumab-aqqg</a>) for <a href="/wiki/Osteoporosis" title="Osteoporosis">osteoporosis</a></li> <li>Imlygic (<a href="/wiki/Talimogene_laherparepvec" title="Talimogene laherparepvec">talimogene laherparepvec</a>) for local treatment of unresectable cutaneous, subcutaneous, and nodal lesions in melanoma recurrent after initial surgery (FDA approved October 2015)<a href="#cite_note-144">[144]</a></li> <li>Kanjinti (<a href="/wiki/Trastuzumab" title="Trastuzumab">trastuzumab</a>-anns)<a href="#cite_note-Kanjinti_approval-80">[80]</a> (FDA approved June 2019)</li> <li>Kyprolis (<a href="/wiki/Carfilzomib" title="Carfilzomib">carfilzomib</a>)</li> <li>Lumakras (<a href="/wiki/Sotorasib" title="Sotorasib">sotorasib</a>)<a href="#cite_note-Lumakras_approval-99">[99]</a></li> <li>Mvasi (<a href="/wiki/Bevacizumab" title="Bevacizumab">bevacizumab</a>-awwb)<a href="#cite_note-Mvasi_approval-75">[75]</a></li> <li>Neulasta (<a href="/wiki/Pegfilgrastim" title="Pegfilgrastim">pegfilgrastim</a>) for <a href="/wiki/Neutropenia" title="Neutropenia">neutropenia</a> (FDA approved 2002)<a href="#cite_note-145">[145]</a></li> <li>Neupogen (<a href="/wiki/Granulocyte_colony-stimulating_factor" title="Granulocyte colony-stimulating factor">granulocyte colony-stimulating factor</a>) for <a href="/wiki/Neutropenia" title="Neutropenia">neutropenia</a></li> <li>Nplate (<a href="/wiki/Romiplostim" title="Romiplostim">romiplostim</a>) for chronic <a href="/wiki/Immune_thrombocytopenic_purpura" title="Immune thrombocytopenic purpura">immune thrombocytopenic purpura</a> (FDA approved 2008)<a href="#cite_note-146">[146]</a><a href="#cite_note-147">[147]</a></li> <li>Otezla (<a href="/wiki/Apremilast" title="Apremilast">apremilast</a>)<a href="#cite_note-148">[148]</a></li> <li>Parsabiv (<a href="/wiki/Etelcalcetide" title="Etelcalcetide">etelcalcetide</a>)</li> <li>Prolia (<a href="/wiki/Denosumab" title="Denosumab">denosumab</a>) for postmenopausal <a href="/wiki/Osteoporosis" title="Osteoporosis">osteoporosis</a></li> <li>Repatha (<a href="/wiki/Evolocumab" title="Evolocumab">evolocumab</a>)</li> <li>Riabni (<a href="/wiki/Rituximab" title="Rituximab">rituximab</a>-arrx)<a href="#cite_note-Riabni_approval-93">[93]</a></li> <li>Sensipar/Mimpara (<a href="/wiki/Cinacalcet" title="Cinacalcet">cinacalcet</a> for primary and <a href="/wiki/Secondary_hyperparathyroidism" title="Secondary hyperparathyroidism">secondary hyperparathyroidism</a>, a mineral metabolism complication common in patients with kidney failure) (FDA approved 2004)<a href="#cite_note-149">[149]</a><a href="#cite_note-150">[150]</a></li> <li>Tezspire (<a href="/wiki/Tezepelumab" title="Tezepelumab">tezepelumab</a>-ekko)<a href="#cite_note-Dunleavy-105">[105]</a></li> <li>Tavneos (<a href="/wiki/Avacopan" title="Avacopan">avacopan</a>)</li> <li>Vectibix (<a href="/wiki/Panitumumab" title="Panitumumab">panitumumab</a> for <a href="/wiki/Colon_cancer" class="mw-redirect" title="Colon cancer">colon cancer</a>) (FDA approved 2006)<a href="#cite_note-151">[151]</a></li> <li>Xgeva (<a href="/wiki/Denosumab" title="Denosumab">denosumab</a>) for the prevention of skeletal-related events (pathological fracture, radiation to bone, spinal cord compression or surgery to bone in adults with bone metastases from solid tumors)</li></ul> <div class="mw-heading mw-heading3"><h3 id="Products_developed_and_then_sold_off">Products developed and then sold off</h3>[<a href="/w/index.php?title=Amgen&action=edit&section=7" title="Edit section: Products developed and then sold off">edit</a>]</div> <ul><li>Kepivance (<a href="/wiki/Palifermin" title="Palifermin">palifermin</a> for <a href="/wiki/Oral_mucositis" class="mw-redirect" title="Oral mucositis">oral mucositis</a>, sold to Biovitrium, now <a href="/wiki/Swedish_Orphan_Biovitrum" title="Swedish Orphan Biovitrum">Swedish Orphan Biovitrum</a>, in December 2008<a href="#cite_note-BiovitriumDeal-152">[152]</a></li> <li>StemGen (<a href="/wiki/Ancestim" title="Ancestim">ancestim</a>) for use in combination with <a href="/wiki/Filgrastim" title="Filgrastim">filgrastim</a> for mobilizing peripheral <a href="/wiki/Hematopoietic_stem_cells" class="mw-redirect" title="Hematopoietic stem cells">hematopoietic stem cells</a><a href="#cite_note-153">[153]</a>) (sold to Biovitrium, now Swedish Orphan Biovitrum, in December 2008)<a href="#cite_note-BiovitriumDeal-152">[152]</a></li> <li>Kineret (<a href="/wiki/Anakinra" title="Anakinra">anakinra</a>) for <a href="/wiki/Rheumatoid_arthritis" title="Rheumatoid arthritis">rheumatoid arthritis</a>, exclusively licensed to Biovitrium, now Swedish Orphan Biovitrum, in December 2008<a href="#cite_note-BiovitriumDeal-152">[152]</a></li></ul> In 2019, the company's largest selling products were Enbrel (<a href="/wiki/Etanercept" title="Etanercept">etanercept</a>),<a href="#cite_note-154">[154]</a> a <a href="/wiki/Tumor_necrosis_factor" title="Tumor necrosis factor">tumor necrosis factor</a> blocker used in the treatment of <a href="/wiki/Rheumatoid_arthritis" title="Rheumatoid arthritis">rheumatoid arthritis</a> and other autoimmune diseases, and Neulasta (<a href="/wiki/Pegfilgrastim" title="Pegfilgrastim">pegfilgrastim</a>), an <a href="/wiki/Immunostimulator" class="mw-redirect" title="Immunostimulator">immunostimulator</a> used to prevent infections in patients undergoing cancer <a href="/wiki/Chemotherapy" title="Chemotherapy">chemotherapy</a>.<a href="#cite_note-155">[155]</a> <div class="mw-heading mw-heading2"><h2 id="Pipeline_and_clinical_trials">Pipeline and clinical trials</h2>[<a href="/w/index.php?title=Amgen&action=edit&section=8" title="Edit section: Pipeline and clinical trials">edit</a>]</div> As of August 2022, Amgen had 17 clinical programs underway in Phase III, eight in Phase II, and 19 in Phase I.<a href="#cite_note-156">[156]</a> In September 2019, FDA granted <a href="/wiki/Fast_track_designation" class="mw-redirect" title="Fast track designation">fast track designation</a> to <a href="/wiki/Sotorasib" title="Sotorasib">sotorasib</a> for the treatment of metastatic <a href="/wiki/Non-small-cell_lung_carcinoma" class="mw-redirect" title="Non-small-cell lung carcinoma">non-small-cell lung carcinoma</a> (NSCLC) with the KRAS G12C mutation.<a href="#cite_note-157">[157]</a> In August 2020, Amgen, <a href="/wiki/Takeda_Pharmaceutical_Company" title="Takeda Pharmaceutical Company">Takeda</a>, and <a href="/wiki/AbbVie" title="AbbVie">AbbVie</a>, as part of a COVID-19 research and development (R&D) alliance, announced the first patients enrolled in the I-SPY COVID clinical trial. The trial evaluated the efficacy of Otezla and two other medicines in severely ill, hospitalized COVID-19 patients who required high-flow oxygen.<a href="#cite_note-158">[158]</a> In October 2020, Amgen announced positive topline Phase 2 results from the CodeBreaK 100 clinical study, evaluating sotorasib in 126 patients with KRAS G12C-mutant advanced NSCLC who had failed three or fewer prior lines of anti-cancer therapies (including <a href="/wiki/Immunotherapy" title="Immunotherapy">immunotherapy</a> and/or chemotherapy).<a href="#cite_note-159">[159]</a> Amgen, the Global Coalition for Adaptive Research, and <a href="/wiki/Eisai_(company)" title="Eisai (company)">Eisai Co., Ltd.</a> also announced enrollment of the first patient in a study testing multiple interventions for the treatment of patients hospitalized with COVID-19.<a href="#cite_note-160">[160]</a><a href="#cite_note-161">[161]</a> In November 2020, Amgen, Takeda, and <a href="/wiki/UCB_(company)" title="UCB (company)">UCB</a>, as part of the COVID R&D alliance, announced the first patient enrolled in another trial evaluating Otezla and two other drugs as treatments for COVID-19.<a href="#cite_note-162">[162]</a> Amgen also announced that it would terminate its collaboration with <a href="/wiki/Cytokinetics" title="Cytokinetics">Cytokinetics</a> and transition the development and commercialization rights for <a href="/wiki/Omecamtiv_mecarbil" title="Omecamtiv mecarbil">omecamtiv mecarbil</a> and AMG 594.<a href="#cite_note-163">[163]</a> Amgen and <a href="/wiki/AstraZeneca" title="AstraZeneca">AstraZeneca</a> announced positive topline results from a Phase 3 trial in which the investigational medicine <a href="/wiki/Tezepelumab" title="Tezepelumab">tezepelumab</a> demonstrated a statistically significant reduction in exacerbations in patients with severe asthma.<a href="#cite_note-164">[164]</a> In December 2020, the FDA granted <a href="/wiki/Breakthrough_therapy" title="Breakthrough therapy">breakthrough therapy</a> designation to sotorasib for advanced or metastatic non-small cell lung cancer patients with KRAS G12C mutation.<a href="#cite_note-165">[165]</a> In May 2021, sotorasib received accelerated approval from FDA for treatment of adult patients with NSCLC whose tumors have a KRAS G12C mutation and who have received at least one prior systemic therapy; this was the first approved targeted therapy for tumors with any KRAS mutation.<a href="#cite_note-166">[166]</a> Similar approvals for sotorasib in NSCLC followed in January 2022 in Europe<a href="#cite_note-167">[167]</a> and Japan.<a href="#cite_note-168">[168]</a> In September 2022, data from a late-stage study showed the company's cancer pill Lumakras beating out chemotherapy. This was the first approved drug in the set of treatments that target KRAS, among the most common generic mutations found in cancers but one where researchers have struggled for years to design drugs to treat. The drug was approved in 2021 with a list price of $17,900 per month.<a href="#cite_note-169">[169]</a> In March 2025, data for the drug Tezspire, showed the best results for treating chronic rhinosinusitis with nasal polyps.<a href="#cite_note-170">[170]</a> In the same month, Amgen announced the start of two late-stage trials for MariTide, a weight loss drug.<a href="#cite_note-171">[171]</a><a href="#cite_note-172">[172]</a> <div class="mw-heading mw-heading2"><h2 id="Carbon_footprint">Carbon footprint</h2>[<a href="/w/index.php?title=Amgen&action=edit&section=9" title="Edit section: Carbon footprint">edit</a>]</div> Amgen reported Total <a href="/wiki/Carbon_footprint" title="Carbon footprint">CO2e emissions</a> (Direct + Indirect) for the twelve months ending 31 December 2020 at 243 Kt (-6 /-2.4% y-o-y)<a href="#cite_note-Amgen_Total_CO2e_emissions-173">[173]</a> and aims to reach net zero emissions by 2027.<a href="#cite_note-174">[174]</a> <table class="wikitable"> <caption>Amgen's annual Total CO2e Emissions - Location-Based Scope 1 + Scope 2 (in kilotonnes)<a href="#cite_note-Amgen_Total_CO2e_emissions-173">[173]</a> </caption> <tbody><tr> <th>Dec 2014</th> <th>Dec 2015</th> <th>Dec 2016</th> <th>Dec 2017</th> <th>Dec 2018</th> <th>Dec 2019</th> <th>Dec 2020 </th></tr> <tr> <td>354</td> <td>369</td> <td>292</td> <td>279</td> <td>264</td> <td>249</td> <td>243 </td></tr></tbody></table> <div class="mw-heading mw-heading2"><h2 id="Controversies">Controversies</h2>[<a href="/w/index.php?title=Amgen&action=edit&section=10" title="Edit section: Controversies">edit</a>]</div> The <a href="/wiki/Los_Angeles_Times" title="Los Angeles Times">Los Angeles Times</a> reported on December 18, 2012, that Amgen pleaded guilty and agreed to pay $150 million in criminal penalty and $612 million to resolve 11 related <a href="/wiki/Whistleblower" class="mw-redirect" title="Whistleblower">whistleblower</a> complaints. Federal prosecutors accused the company of pursuing profits while putting patients at risk.<a href="#cite_note-175">[175]</a> Larry Husten, a contributor at Forbes.com elaborates on AMGEN's illegal marketing practices in this case, namely that the "government accused Amgen of marketing Aranesp for indications not approved by the FDA and other illegal marketing practices".<a href="#cite_note-176">[176]</a> <div class="mw-heading mw-heading2"><h2 id="Public-private_engagement">Public-private engagement</h2>[<a href="/w/index.php?title=Amgen&action=edit&section=11" title="Edit section: Public-private engagement">edit</a>]</div> Amgen engages with the public and private sectors in a variety of settings including to promote <a href="/wiki/Research_and_development" title="Research and development">research and development</a>, academic funding, event sponsorship, <a href="/wiki/Philanthropy" title="Philanthropy">philanthropy</a>, and <a href="/wiki/Political_lobbying" class="mw-redirect" title="Political lobbying">political lobbying</a>. <div class="mw-heading mw-heading3"><h3 id="Academia">Academia</h3>[<a href="/w/index.php?title=Amgen&action=edit&section=12" title="Edit section: Academia">edit</a>]</div> <ul><li><a href="/wiki/Institute_for_Advanced_Study" title="Institute for Advanced Study">Institute for Advanced Study</a> - Donor to various IAS campaigns, including the IAS/Park City Mathematics Institute (PCMI), the Regional Initiative in Science and Education (RISE), and the Opportunity Equation (OE).<a href="#cite_note-177">[177]</a></li> <li><a href="/w/index.php?title=LA_Promise_Fund&action=edit&redlink=1" class="new" title="LA Promise Fund (page does not exist)">LA Promise Fund</a> - Sponsor of the Amgen Biotech Experience Los Angeles (ABE-LA).<a href="#cite_note-178">[178]</a></li> <li><a href="/wiki/University_of_Toronto" title="University of Toronto">University of Toronto</a> - Donor to U of T's Boundless campaign.<a href="#cite_note-179">[179]</a></li> <li><a href="/wiki/University_of_Washington" title="University of Washington">University of Washington</a> - Donor.<a href="#cite_note-180">[180]</a></li></ul> <div class="mw-heading mw-heading3"><h3 id="Events_and_conferences">Events and conferences</h3>[<a href="/w/index.php?title=Amgen&action=edit&section=13" title="Edit section: Events and conferences">edit</a>]</div> <ul><li>Alberta Kidney Days - Virtual series sponsor.<a href="#cite_note-181">[181]</a></li> <li>BC Kidney Days - Sponsor.<a href="#cite_note-182">[182]</a></li> <li>Mentoring in IBD - Sponsor.<a href="#cite_note-183">[183]</a></li> <li><a href="/wiki/Princess_Margaret_Cancer_Centre" title="Princess Margaret Cancer Centre">Princess Margaret Cancer Centre</a> (PMCC) Conference - Sponsor.<a href="#cite_note-184">[184]</a></li></ul> <div class="mw-heading mw-heading3"><h3 id="Health_care">Health care</h3>[<a href="/w/index.php?title=Amgen&action=edit&section=14" title="Edit section: Health care">edit</a>]</div> <ul><li><a href="/wiki/Kingston_General_Hospital" title="Kingston General Hospital">Kingston General Hospital</a> - Donor.<a href="#cite_note-185">[185]</a></li> <li><a href="/wiki/Princess_Margaret_Cancer_Centre" title="Princess Margaret Cancer Centre">Princess Margaret Cancer Centre</a> - Donor to the Princess Margaret Cancer Foundation.<a href="#cite_note-186">[186]</a></li> <li><a href="/wiki/Providence_Health_Care_(Vancouver)" title="Providence Health Care (Vancouver)">Providence Health Care</a> - Donor.<a href="#cite_note-187">[187]</a></li> <li><a href="/wiki/Scarborough_Health_Network" title="Scarborough Health Network">Scarborough Health Network</a> - Donor to the SHN Foundation.<a href="#cite_note-188">[188]</a></li> <li><a href="/wiki/SickKids" class="mw-redirect" title="SickKids">SickKids</a> - Donor to the SickKids Foundation.<a href="#cite_note-189">[189]</a></li> <li><a href="/wiki/Sinai_Health_System" title="Sinai Health System">Sinai Health System</a> - Donor to the Sinai Health Foundation.<a href="#cite_note-190">[190]</a></li> <li><a href="/wiki/St._Michael%27s_Hospital_(Toronto)" title="St. Michael's Hospital (Toronto)">St. Michael's Hospital</a> - Donor.<a href="#cite_note-:0-191">[191]</a></li> <li><a href="/wiki/Sunnybrook_Health_Sciences_Centre" title="Sunnybrook Health Sciences Centre">Sunnybrook Health Sciences Centre</a> - Donor to the Sunnybrook Foundation.<a href="#cite_note-192">[192]</a></li> <li><a href="/wiki/Unity_Health_Toronto" title="Unity Health Toronto">Unity Health Toronto</a> - Donor.<a href="#cite_note-:0-191">[191]</a></li> <li><a href="/wiki/University_Health_Network" title="University Health Network">University Health Network</a> - Donor to the UHN Foundation.<a href="#cite_note-193">[193]</a></li> <li><a href="/wiki/Women%27s_College_Hospital" title="Women's College Hospital">Women's College Hospital</a> - Donor.<a href="#cite_note-194">[194]</a></li></ul> <div class="mw-heading mw-heading3"><h3 id="Media">Media</h3>[<a href="/w/index.php?title=Amgen&action=edit&section=15" title="Edit section: Media">edit</a>]</div> <ul><li><a href="/wiki/National_Geographic_Society" title="National Geographic Society">National Geographic Society</a> - Donor.<a href="#cite_note-195">[195]</a></li></ul> <div class="mw-heading mw-heading3"><h3 id="Medical_societies">Medical societies</h3>[<a href="/w/index.php?title=Amgen&action=edit&section=16" title="Edit section: Medical societies">edit</a>]</div> <ul><li><a href="/wiki/American_Society_of_Hematology" title="American Society of Hematology">American Society of Hematology</a> - Corporate funder.<a href="#cite_note-196">[196]</a></li> <li><a href="/w/index.php?title=Arthritis_Society&action=edit&redlink=1" class="new" title="Arthritis Society (page does not exist)">Arthritis Society</a> (Canada) - Partner.<a href="#cite_note-197">[197]</a></li> <li><a href="/wiki/Canadian_Society_of_Hospital_Pharmacists" title="Canadian Society of Hospital Pharmacists">Canadian Society of Hospital Pharmacists</a> - Donor to the CSHP Foundation.<a href="#cite_note-198">[198]</a></li> <li><a href="/w/index.php?title=Canadian_Society_of_Nephrology&action=edit&redlink=1" class="new" title="Canadian Society of Nephrology (page does not exist)">Canadian Society of Nephrology</a> - Corporate partner.<a href="#cite_note-199">[199]</a></li> <li><a href="/wiki/Endocrine_Society" title="Endocrine Society">Endocrine Society</a> - Corporate liaison board member.<a href="#cite_note-200">[200]</a></li> <li><a href="/wiki/European_Society_of_Cardiology" title="European Society of Cardiology">European Society of Cardiology</a> - Sponsor for the EORP registry programme.<a href="#cite_note-201">[201]</a></li> <li><a href="/w/index.php?title=Federation_of_Medical_Women_in_Canada&action=edit&redlink=1" class="new" title="Federation of Medical Women in Canada (page does not exist)">Federation of Medical Women in Canada</a> - Sponsor.<a href="#cite_note-202">[202]</a></li></ul> <div class="mw-heading mw-heading3"><h3 id="Political_lobbying">Political lobbying</h3>[<a href="/w/index.php?title=Amgen&action=edit&section=17" title="Edit section: Political lobbying">edit</a>]</div> <ul><li><a href="/w/index.php?title=Alliance_for_a_Stronger_FDA&action=edit&redlink=1" class="new" title="Alliance for a Stronger FDA (page does not exist)">Alliance for a Stronger FDA</a> - Member.<a href="#cite_note-203">[203]</a></li> <li><a href="/wiki/Alliance_for_Aging_Research" title="Alliance for Aging Research">Alliance for Aging Research</a> - Donor.<a href="#cite_note-204">[204]</a></li> <li><a href="/wiki/BIOTECanada" title="BIOTECanada">BIOTECanada</a> - Member.<a href="#cite_note-205">[205]</a></li> <li><a href="/wiki/Bipartisan_Policy_Center" title="Bipartisan Policy Center">Bipartisan Policy Center</a> - Donor.<a href="#cite_note-206">[206]</a></li> <li><a href="/wiki/The_Business_Council" title="The Business Council">The Business Council</a> - Member, represented by Amgen chairman and CEO <a href="/wiki/Robert_A._Bradway" title="Robert A. Bradway">Robert A. Bradway</a>.<a href="#cite_note-207">[207]</a></li> <li><a href="/wiki/CDC_Foundation" class="mw-redirect" title="CDC Foundation">CDC Foundation</a> - Funding partner.<a href="#cite_note-208">[208]</a></li> <li><a href="/w/index.php?title=Centre_for_Commercialization_of_Regenerative_Medicine&action=edit&redlink=1" class="new" title="Centre for Commercialization of Regenerative Medicine (page does not exist)">Centre for Commercialization of Regenerative Medicine</a> (CCRM) - Industry partner.<a href="#cite_note-209">[209]</a></li> <li><a href="/wiki/Council_on_Foreign_Relations" title="Council on Foreign Relations">Council on Foreign Relations</a> - Affiliate.<a href="#cite_note-210">[210]</a></li> <li><a href="/wiki/European_Federation_of_Pharmaceutical_Industries_and_Associations" title="European Federation of Pharmaceutical Industries and Associations">European Federation of Pharmaceutical Industries and Associations</a> (EFPIA) - Member.<a href="#cite_note-211">[211]</a></li> <li><a href="/wiki/Foundation_for_the_National_Institutes_of_Health" title="Foundation for the National Institutes of Health">Foundation for the National Institutes of Health</a> (FNIH) - Donor.<a href="#cite_note-212">[212]</a></li> <li><a href="/w/index.php?title=Global_Health_Progress&action=edit&redlink=1" class="new" title="Global Health Progress (page does not exist)">Global Health Progress</a> - Partner.<a href="#cite_note-213">[213]</a> GHP is a multinational resource hub hosted by the <a href="/wiki/International_Federation_of_Pharmaceutical_Manufacturers_%26_Associations" title="International Federation of Pharmaceutical Manufacturers & Associations">International Federation of Pharmaceutical Manufacturers & Associations</a> (IFPMA).</li> <li><a href="/w/index.php?title=Health_Products_Stewardship_Association&action=edit&redlink=1" class="new" title="Health Products Stewardship Association (page does not exist)">Health Products Stewardship Association</a> - Member.<a href="#cite_note-214">[214]</a></li> <li><a href="/wiki/Innovative_Medicines_Canada" title="Innovative Medicines Canada">Innovative Medicines Canada</a> - Member company.<a href="#cite_note-215">[215]</a></li> <li><a href="/wiki/International_Federation_of_Pharmaceutical_Manufacturers_%26_Associations" title="International Federation of Pharmaceutical Manufacturers & Associations">International Federation of Pharmaceutical Manufacturers & Associations</a> (IFPMA) - Member.<a href="#cite_note-216">[216]</a></li> <li><a href="/w/index.php?title=Life_Sciences_British_Columbia&action=edit&redlink=1" class="new" title="Life Sciences British Columbia (page does not exist)">Life Sciences British Columbia</a> - Sponsor.<a href="#cite_note-217">[217]</a></li> <li><a href="/wiki/Mayor_of_Los_Angeles" title="Mayor of Los Angeles">Mayor's Fund for Los Angeles</a> - Disaster relief grant provider.<a href="#cite_note-218">[218]</a></li> <li><a href="/wiki/National_Health_Council" title="National Health Council">National Health Council</a> - Member.<a href="#cite_note-219">[219]</a></li> <li><a href="/w/index.php?title=Personalized_Medicine_Coalition&action=edit&redlink=1" class="new" title="Personalized Medicine Coalition (page does not exist)">Personalized Medicine Coalition</a> - Member.<a href="#cite_note-220">[220]</a></li> <li><a href="/wiki/Pharmaceutical_Advertising_Advisory_Board" title="Pharmaceutical Advertising Advisory Board">Pharmaceutical Advertising Advisory Board</a> (PAAB) - Client.<a href="#cite_note-221">[221]</a> PAAB "maintains a collaborative relationship” with <a href="/wiki/Health_Canada" title="Health Canada">Health Canada</a>.</li> <li><a href="/wiki/Pharmaceutical_Research_and_Manufacturers_of_America" title="Pharmaceutical Research and Manufacturers of America">Pharmaceutical Research and Manufacturers of America</a> (PhRMA) - Member.<a href="#cite_note-222">[222]</a></li> <li><a href="/wiki/Reagan-Udall_Foundation" title="Reagan-Udall Foundation">Reagan-Udall Foundation for the Food and Drug Administration</a> - Donor.<a href="#cite_note-223">[223]</a></li> <li><a href="/w/index.php?title=Research!America&action=edit&redlink=1" class="new" title="Research!America (page does not exist)">Research!America</a> - Member.<a href="#cite_note-224">[224]</a></li></ul> <div class="mw-heading mw-heading3"><h3 id="Professional_associations">Professional associations</h3>[<a href="/w/index.php?title=Amgen&action=edit&section=18" title="Edit section: Professional associations">edit</a>]</div> <ul><li><a href="/w/index.php?title=British_Columbia_Pharmacy_Association&action=edit&redlink=1" class="new" title="British Columbia Pharmacy Association (page does not exist)">British Columbia Pharmacy Association</a> - Sponsor.<a href="#cite_note-225">[225]</a></li> <li><a href="/wiki/Canadian_Association_of_Gastroenterology" title="Canadian Association of Gastroenterology">Canadian Association of Gastroenterology</a> - Corporate sponsor.<a href="#cite_note-226">[226]</a></li> <li><a href="/w/index.php?title=Canadian_Association_of_Radiologists&action=edit&redlink=1" class="new" title="Canadian Association of Radiologists (page does not exist)">Canadian Association of Radiologists</a> - Corporate partner.<a href="#cite_note-227">[227]</a></li> <li><a href="/wiki/Canadian_Rheumatology_Association" title="Canadian Rheumatology Association">Canadian Rheumatology Association</a> - Corporate sponsor.<a href="#cite_note-228">[228]</a></li> <li><a href="/w/index.php?title=Canadian_Urological_Association&action=edit&redlink=1" class="new" title="Canadian Urological Association (page does not exist)">Canadian Urological Association</a> - Corporate sponsor.<a href="#cite_note-229">[229]</a></li> <li><a href="/w/index.php?title=Colorectal_Cancer_Canada&action=edit&redlink=1" class="new" title="Colorectal Cancer Canada (page does not exist)">Colorectal Cancer Canada</a> - Sponsor.<a href="#cite_note-230">[230]</a></li> <li><a href="/wiki/Ontario_Medical_Association" title="Ontario Medical Association">Ontario Medical Association</a> - Donor.<a href="#cite_note-231">[231]</a></li></ul> <div class="mw-heading mw-heading3"><h3 id="Research_and_development">Research and development</h3>[<a href="/w/index.php?title=Amgen&action=edit&section=19" title="Edit section: Research and development">edit</a>]</div> <ul><li><a href="/w/index.php?title=Alberta_Kidney_Disease_Network&action=edit&redlink=1" class="new" title="Alberta Kidney Disease Network (page does not exist)">Alberta Kidney Disease Network</a> - Grant provider.<a href="#cite_note-232">[232]</a></li> <li><a href="/w/index.php?title=Can-SOLVE_CKD_Network&action=edit&redlink=1" class="new" title="Can-SOLVE CKD Network (page does not exist)">Can-SOLVE CKD Network</a> - Funding partner.<a href="#cite_note-233">[233]</a></li> <li><a href="/wiki/Urban_Institute" title="Urban Institute">Urban Institute</a> - Donor.<a href="#cite_note-234">[234]</a></li></ul> <div class="mw-heading mw-heading2"><h2 id="Awards_and_recognition">Awards and recognition</h2>[<a href="/w/index.php?title=Amgen&action=edit&section=20" title="Edit section: Awards and recognition">edit</a>]</div> Amgen was ranked 151 on the Fortune 500 list of the largest United States corporations by revenue in 2024.<a href="#cite_note-235">[235]</a> <div class="mw-heading mw-heading2"><h2 id="See_also">See also</h2>[<a href="/w/index.php?title=Amgen&action=edit&section=21" title="Edit section: See also">edit</a>]</div> <style data-mw-deduplicate="TemplateStyles:r1266661725">.mw-parser-output .portalbox{padding:0;margin:0.5em 0;display:table;box-sizing:border-box;max-width:175px;list-style:none}.mw-parser-output .portalborder{border:1px solid var(--border-color-base,#a2a9b1);padding:0.1em;background:var(--background-color-neutral-subtle,#f8f9fa)}.mw-parser-output .portalbox-entry{display:table-row;font-size:85%;line-height:110%;height:1.9em;font-style:italic;font-weight:bold}.mw-parser-output .portalbox-image{display:table-cell;padding:0.2em;vertical-align:middle;text-align:center}.mw-parser-output .portalbox-link{display:table-cell;padding:0.2em 0.2em 0.2em 0.3em;vertical-align:middle}@media(min-width:720px){.mw-parser-output .portalleft{margin:0.5em 1em 0.5em 0}.mw-parser-output .portalright{clear:right;float:right;margin:0.5em 0 0.5em 1em}}</style><ul role="navigation" aria-label="Portals" class="noprint portalbox portalborder portalright"> <li class="portalbox-entry"><img alt="flag" src="//upload.wikimedia.org/wikipedia/commons/thumb/0/01/Flag_of_California.svg/32px-Flag_of_California.svg.png" decoding="async" width="32" height="21" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/0/01/Flag_of_California.svg/48px-Flag_of_California.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/0/01/Flag_of_California.svg/64px-Flag_of_California.svg.png 2x" data-file-width="900" data-file-height="600" /><a href="/wiki/Portal:California" title="Portal:California">California portal</a></li><li class="portalbox-entry"><img alt="" src="//upload.wikimedia.org/wikipedia/commons/thumb/2/2a/Industry5.svg/28px-Industry5.svg.png" decoding="async" width="28" height="28" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/2/2a/Industry5.svg/42px-Industry5.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/2/2a/Industry5.svg/56px-Industry5.svg.png 2x" data-file-width="512" data-file-height="512" /><a href="/wiki/Portal:Companies" title="Portal:Companies">Companies portal</a></li></ul> <ul><li><a href="/wiki/Kirin-Amgen_v_Hoechst_Marion_Roussel" class="mw-redirect" title="Kirin-Amgen v Hoechst Marion Roussel">Kirin-Amgen v Hoechst Marion Roussel</a>, a <a href="/wiki/United_Kingdom" title="United Kingdom">UK</a> <a href="/wiki/Patent" title="Patent">patent</a> case decided by the <a href="/wiki/House_of_Lords" title="House of Lords">House of Lords</a></li> <li><a href="/wiki/Amgen_Inc._v._Harris" class="mw-redirect" title="Amgen Inc. v. Harris">Amgen Inc. v. Harris</a>, a United States Supreme Court case on employment law.</li> <li><a href="/wiki/Evolocumab" title="Evolocumab">Evolocumab</a></li> <li><a href="/wiki/Amgen_Inc_v._Sanofi" title="Amgen Inc v. Sanofi">Amgen Inc v. Sanofi</a>, a United States Supreme Court case on patent enablement.</li></ul> <div class="mw-heading mw-heading2"><h2 id="References">References</h2>[<a href="/w/index.php?title=Amgen&action=edit&section=22" title="Edit section: References">edit</a>]</div> <style data-mw-deduplicate="TemplateStyles:r1239543626">.mw-parser-output .reflist{margin-bottom:0.5em;list-style-type:decimal}@media screen{.mw-parser-output .reflist{font-size:90%}}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output .reflist-columns-2{column-width:30em}.mw-parser-output .reflist-columns-3{column-width:25em}.mw-parser-output .reflist-columns{margin-top:0.3em}.mw-parser-output .reflist-columns ol{margin-top:0}.mw-parser-output .reflist-columns li{page-break-inside:avoid;break-inside:avoid-column}.mw-parser-output .reflist-upper-alpha{list-style-type:upper-alpha}.mw-parser-output .reflist-upper-roman{list-style-type:upper-roman}.mw-parser-output .reflist-lower-alpha{list-style-type:lower-alpha}.mw-parser-output .reflist-lower-greek{list-style-type:lower-greek}.mw-parser-output .reflist-lower-roman{list-style-type:lower-roman}</style><div class="reflist reflist-columns references-column-width reflist-columns-2"> <ol class="references"> <li id="cite_note-quickfacts2020-1"><a href="#cite_ref-quickfacts2020_1-0">^</a> <style data-mw-deduplicate="TemplateStyles:r1238218222">.mw-parser-output cite.citation{font-style:inherit;word-wrap:break-word}.mw-parser-output .citation q{quotes:"\"""\"""'""'"}.mw-parser-output .citation:target{background-color:rgba(0,127,255,0.133)}.mw-parser-output .id-lock-free.id-lock-free a{background:url("//upload.wikimedia.org/wikipedia/commons/6/65/Lock-green.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-limited.id-lock-limited a,.mw-parser-output .id-lock-registration.id-lock-registration a{background:url("//upload.wikimedia.org/wikipedia/commons/d/d6/Lock-gray-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-subscription.id-lock-subscription a{background:url("//upload.wikimedia.org/wikipedia/commons/a/aa/Lock-red-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .cs1-ws-icon a{background:url("//upload.wikimedia.org/wikipedia/commons/4/4c/Wikisource-logo.svg")right 0.1em center/12px no-repeat}body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-free a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-limited a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-registration a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-subscription a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .cs1-ws-icon a{background-size:contain;padding:0 1em 0 0}.mw-parser-output .cs1-code{color:inherit;background:inherit;border:none;padding:inherit}.mw-parser-output .cs1-hidden-error{display:none;color:var(--color-error,#d33)}.mw-parser-output .cs1-visible-error{color:var(--color-error,#d33)}.mw-parser-output .cs1-maint{display:none;color:#085;margin-left:0.3em}.mw-parser-output .cs1-kern-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right{padding-right:0.2em}.mw-parser-output .citation .mw-selflink{font-weight:inherit}@media screen{.mw-parser-output .cs1-format{font-size:95%}html.skin-theme-clientpref-night .mw-parser-output .cs1-maint{color:#18911f}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .cs1-maint{color:#18911f}}</style><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://wwwext.amgen.com/~/media/amgen/full/www-amgen-com/downloads/fact-sheets/fact_sheet_amgen.ashx">"About Amgen Fact Sheet"</a>. amgen.com. Retrieved 9 March 2020.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=amgen.com&rft.atitle=About+Amgen+Fact+Sheet&rft_id=https%3A%2F%2Fwwwext.amgen.com%2F~%2Fmedia%2Famgen%2Ffull%2Fwww-amgen-com%2Fdownloads%2Ffact-sheets%2Ffact_sheet_amgen.ashx&rfr_id=info%3Asid%2Fen.wikipedia.org%3AAmgen" class="Z3988"> </li> <li id="cite_note-2"><a href="#cite_ref-2">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.sec.gov/ix?doc=/Archives/edgar/data/318154/000031815425000010/amgn-20241231.htm">"2024 Annual Report (Form 10-K)"</a>. <a href="/wiki/U.S._Securities_and_Exchange_Commission" title="U.S. Securities and Exchange Commission">U.S. Securities and Exchange Commission</a>. February 14, 2025.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=2024+Annual+Report+%28Form+10-K%29&rft.pub=U.S.+Securities+and+Exchange+Commission&rft.date=2025-02-14&rft_id=https%3A%2F%2Fwww.sec.gov%2Fix%3Fdoc%3D%2FArchives%2Fedgar%2Fdata%2F318154%2F000031815425000010%2Famgn-20241231.htm&rfr_id=info%3Asid%2Fen.wikipedia.org%3AAmgen" class="Z3988"> </li> <li id="cite_note-3"><a href="#cite_ref-3">^</a> <a rel="nofollow" class="external text" href="http://www.amgenhistory.com/">Amgen History official site</a> page accessed January 2, 2016 </li> <li id="cite_note-4"><a href="#cite_ref-4">^</a> Ronald Vogel. Pharmaceutical Economics and Public Policy. CRC Press, 2007. <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><a href="/wiki/ISBN_(identifier)" class="mw-redirect" title="ISBN (identifier)">ISBN</a> <a href="/wiki/Special:BookSources/9781439801345" title="Special:BookSources/9781439801345">9781439801345</a>. <a rel="nofollow" class="external text" href="https://books.google.com/books?id=ejNC3HJmjhwC&pg=PA208">P. 208</a> </li> <li id="cite_note-Talhelm-5"><a href="#cite_ref-Talhelm_5-0">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFTalhelm2022" class="citation news cs1">Talhelm, Matt (7 March 2022). <a rel="nofollow" class="external text" href="https://wraltechwire.com/2022/03/07/amgen-to-officially-break-ground-on-550-million-facility-in-holly-springs/">"Amgen to offer workers an average salary of $119,510 at new facility"</a>. WRAL TechWire. Retrieved 20 September 2022.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=WRAL+TechWire&rft.atitle=Amgen+to+offer+workers+an+average+salary+of+%24119%2C510+at+new+facility&rft.date=2022-03-07&rft.aulast=Talhelm&rft.aufirst=Matt&rft_id=https%3A%2F%2Fwraltechwire.com%2F2022%2F03%2F07%2Famgen-to-officially-break-ground-on-550-million-facility-in-holly-springs%2F&rfr_id=info%3Asid%2Fen.wikipedia.org%3AAmgen" class="Z3988"> </li> <li id="cite_note-6"><a href="#cite_ref-6">^</a> Bidwell, Carol A. (1989). The Conejo Valley: Old and New Frontiers. 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Retrieved 2022-08-05.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=Pharmaceutical+Research+and+Manufacturers+of+America&rft.atitle=About&rft_id=https%3A%2F%2Fphrma.org%2FAbout&rfr_id=info%3Asid%2Fen.wikipedia.org%3AAmgen" class="Z3988"> </li> <li id="cite_note-223"><a href="#cite_ref-223">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFWincklerWoodcock2021" class="citation web cs1">Winckler, Susan C.; Woodcock, Janet (2021-07-01). <a rel="nofollow" class="external text" href="https://reaganudall.org/sites/default/files/2021-07/7-1-21_Reagan-Udall_AR.pdf">"Annual Report 2020"</a> (PDF). <a href="/wiki/Reagan-Udall_Foundation" title="Reagan-Udall Foundation">Reagan-Udall Foundation</a>. <a rel="nofollow" class="external text" href="https://web.archive.org/web/20220712065838/https://reaganudall.org/sites/default/files/2021-07/7-1-21_Reagan-Udall_AR.pdf">Archived</a> (PDF) from the original on 2022-07-12. 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Can-SOLVE CKD Network. 2022. <a rel="nofollow" class="external text" href="https://web.archive.org/web/20220802200756/https://cansolveckd.ca/about/funding-partners/">Archived</a> from the original on 2022-08-02. Retrieved 2022-08-02.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=Can-SOLVE+CKD+Network&rft.atitle=Funding+Partners&rft.date=2022&rft_id=https%3A%2F%2Fcansolveckd.ca%2Fabout%2Ffunding-partners%2F&rfr_id=info%3Asid%2Fen.wikipedia.org%3AAmgen" class="Z3988"> </li> <li id="cite_note-234"><a href="#cite_ref-234">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite id="CITEREFWartell" class="citation web cs1">Wartell, Sarah Rosen. <a rel="nofollow" class="external text" href="https://www.urban.org/sites/default/files/2021/11/01/2020-annual-report.pdf">"2020 Annual Report"</a> (PDF). <a href="/wiki/Urban_Institute" title="Urban Institute">Urban Institute</a>. <a rel="nofollow" class="external text" href="https://web.archive.org/web/20220630041643/https://www.urban.org/sites/default/files/2021/11/01/2020-annual-report.pdf">Archived</a> (PDF) from the original on 2022-06-30. Retrieved 2022-08-05.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=Urban+Institute&rft.atitle=2020+Annual+Report&rft.aulast=Wartell&rft.aufirst=Sarah+Rosen&rft_id=https%3A%2F%2Fwww.urban.org%2Fsites%2Fdefault%2Ffiles%2F2021%2F11%2F01%2F2020-annual-report.pdf&rfr_id=info%3Asid%2Fen.wikipedia.org%3AAmgen" class="Z3988"> </li> <li id="cite_note-235"><a href="#cite_ref-235">^</a> <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222" /><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.50pros.com/fortune500">"Fortune 500 Full List (2024)"</a>. www.50pros.com. Retrieved 2024-11-12.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=www.50pros.com&rft.atitle=Fortune+500+Full+List+%282024%29&rft_id=https%3A%2F%2Fwww.50pros.com%2Ffortune500&rfr_id=info%3Asid%2Fen.wikipedia.org%3AAmgen" class="Z3988"> </li> </ol></div> <div class="mw-heading mw-heading2"><h2 id="External_links">External links</h2>[<a href="/w/index.php?title=Amgen&action=edit&section=23" title="Edit section: External links">edit</a>]</div> <style data-mw-deduplicate="TemplateStyles:r1235681985">.mw-parser-output .side-box{margin:4px 0;box-sizing:border-box;border:1px solid #aaa;font-size:88%;line-height:1.25em;background-color:var(--background-color-interactive-subtle,#f8f9fa);display:flow-root}.mw-parser-output .side-box-abovebelow,.mw-parser-output .side-box-text{padding:0.25em 0.9em}.mw-parser-output .side-box-image{padding:2px 0 2px 0.9em;text-align:center}.mw-parser-output .side-box-imageright{padding:2px 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campaign finance and lobbying <a href="https://www.wikidata.org/wiki/Q470517#P4691" title="Edit this at Wikidata"><img alt="Edit this at Wikidata" src="//upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/10px-OOjs_UI_icon_edit-ltr-progressive.svg.png" decoding="async" width="10" height="10" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/15px-OOjs_UI_icon_edit-ltr-progressive.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/20px-OOjs_UI_icon_edit-ltr-progressive.svg.png 2x" data-file-width="20" data-file-height="20" /></a></li> <li>Business data for Amgen: <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374" /><div class="hlist inline"><ul><li><a rel="nofollow" class="external text" href="https://www.google.com/finance/quote/AMGN:NASDAQ">Google</a></li><li><a rel="nofollow" class="external text" href="https://www.sec.gov/cgi-bin/browse-edgar?action=getcompany&CIK=318154">SEC filings</a></li><li><a rel="nofollow" class="external text" href="https://finance.yahoo.com/quote/AMGN">Yahoo!</a></li></ul></div></li></ul> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374" /><style data-mw-deduplicate="TemplateStyles:r1236075235">.mw-parser-output .navbox{box-sizing:border-box;border:1px solid #a2a9b1;width:100%;clear:both;font-size:88%;text-align:center;padding:1px;margin:1em auto 0}.mw-parser-output .navbox .navbox{margin-top:0}.mw-parser-output .navbox+.navbox,.mw-parser-output .navbox+.navbox-styles+.navbox{margin-top:-1px}.mw-parser-output .navbox-inner,.mw-parser-output .navbox-subgroup{width:100%}.mw-parser-output .navbox-group,.mw-parser-output .navbox-title,.mw-parser-output .navbox-abovebelow{padding:0.25em 1em;line-height:1.5em;text-align:center}.mw-parser-output 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abbr{color:var(--color-base)!important}}@media print{.mw-parser-output .navbar{display:none!important}}</style><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:Pharmaceutical_companies_of_the_United_States" title="Template:Pharmaceutical companies of the United States"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Pharmaceutical_companies_of_the_United_States" title="Template talk:Pharmaceutical companies of the United States"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Pharmaceutical_companies_of_the_United_States" title="Special:EditPage/Template:Pharmaceutical companies of the United States"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Pharmaceutical_companies_of_the_United_States156" style="font-size:114%;margin:0 4em"><a href="/wiki/Category:Pharmaceutical_companies_of_the_United_States" title="Category:Pharmaceutical companies of the United States">Pharmaceutical companies of the United States</a></div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%">Current</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Abbott_Laboratories" title="Abbott Laboratories">Abbott Laboratories</a></li> <li><a href="/wiki/AbbVie" title="AbbVie">AbbVie Inc.</a></li> <li><a href="/wiki/Acorda_Therapeutics" title="Acorda Therapeutics">Acorda Therapeutics</a></li> <li><a href="/wiki/Advaxis" title="Advaxis">Advaxis</a></li> <li><a href="/wiki/Alcon" title="Alcon">Alcon</a></li> <li><a href="/wiki/Alexion_Pharmaceuticals" title="Alexion Pharmaceuticals">Alexion</a></li> <li><a href="/wiki/Alnylam" class="mw-redirect" title="Alnylam">Alnylam</a></li> <li><a class="mw-selflink selflink">Amgen</a></li> <li><a href="/wiki/Amneal_Pharmaceuticals" title="Amneal Pharmaceuticals">Amneal Pharmaceuticals</a></li> <li><a href="/wiki/Avax_Technologies" title="Avax Technologies">Avax Technologies</a></li> <li><a href="/wiki/Baxter_International" title="Baxter International">Baxter</a></li> <li><a href="/wiki/BioCryst_Pharmaceuticals" title="BioCryst Pharmaceuticals">BioCryst</a></li> <li><a href="/wiki/Biogen" title="Biogen">Biogen</a></li> <li><a href="/wiki/Bioverativ" title="Bioverativ">Bioverativ</a></li> <li><a href="/wiki/Biovest" title="Biovest">Biovest</a></li> <li><a href="/wiki/Biovista" title="Biovista">Biovista</a></li> <li><a href="/wiki/Bristol_Myers_Squibb" title="Bristol Myers Squibb">Bristol Myers Squibb</a></li> <li><a href="/wiki/Century_Pharmaceuticals" title="Century Pharmaceuticals">Century</a></li> <li><a href="/wiki/Ceragenix_Pharmaceuticals" title="Ceragenix Pharmaceuticals">Ceragenix</a></li> <li><a href="/wiki/Combe_Incorporated" title="Combe Incorporated">Combe</a></li> <li><a href="/wiki/CytoSport" title="CytoSport">CytoSport</a></li> <li><a href="/wiki/CytRx" title="CytRx">CytRx</a></li> <li><a href="/wiki/Danco_Laboratories" title="Danco Laboratories">Danco Laboratories</a></li> <li><a href="/wiki/Eli_Lilly_and_Company" title="Eli Lilly and Company">Eli Lilly</a></li> <li><a href="/wiki/Galena_Biopharma" title="Galena Biopharma">Galena Biopharma</a></li> <li><a href="/wiki/Genentech" title="Genentech">Genentech</a></li> <li><a href="/wiki/Gilead_Sciences" title="Gilead Sciences">Gilead Sciences</a></li> <li><a href="/wiki/Ionis_Pharmaceuticals" title="Ionis Pharmaceuticals">Ionis</a></li> <li><a href="/wiki/Institute_for_OneWorld_Health" class="mw-redirect" title="Institute for OneWorld Health">Institute for OneWorld Health</a></li> <li><a href="/wiki/Intercept_Pharmaceuticals" title="Intercept Pharmaceuticals">Intercept</a></li> <li><a href="/wiki/Johnson_%26_Johnson" title="Johnson & Johnson">Johnson & Johnson</a> <ul><li><a href="/wiki/Ethicon" title="Ethicon">Ethicon</a></li> <li><a href="/wiki/Janssen_Biotech" class="mw-redirect" title="Janssen Biotech">Janssen Biotech</a></li> <li><a href="/wiki/McNeil_Consumer_Healthcare" title="McNeil Consumer Healthcare">McNeil Consumer Healthcare</a></li> <li><a href="/wiki/Ortho-McNeil_Pharmaceutical" title="Ortho-McNeil Pharmaceutical">Ortho-McNeil</a></li></ul></li> <li><a href="/wiki/Kinetic_Concepts" title="Kinetic Concepts">Kinetic Concepts</a></li> <li><a href="/wiki/McKesson_Corporation" title="McKesson Corporation">McKesson</a></li> <li><a href="/wiki/Melinta_Therapeutics" title="Melinta Therapeutics">Melinta Therapeutics</a></li> <li><a href="/wiki/Melior_Discovery" title="Melior Discovery">Melior Discovery</a></li> <li><a href="/wiki/Mentholatum" title="Mentholatum">Mentholatum</a></li> <li><a href="/wiki/Merck_%26_Co." title="Merck & Co.">Merck & Co.</a></li> <li><a href="/wiki/Merrimack_Pharmaceuticals" title="Merrimack Pharmaceuticals">Merrimack Pharmaceuticals</a></li> <li><a href="/wiki/Myriad_Genetics" title="Myriad Genetics">Myriad Genetics</a></li> <li><a href="/wiki/Moderna" title="Moderna">Moderna</a></li> <li><a href="/wiki/Northwest_Biotherapeutics" title="Northwest Biotherapeutics">Northwest Biotherapeutics</a></li> <li><a href="/wiki/Norwich_Pharma_Services" title="Norwich Pharma Services">Norwich Pharma</a></li> <li><a href="/wiki/NovaBay_Pharmaceuticals" title="NovaBay Pharmaceuticals">NovaBay</a></li> <li><a href="/wiki/Organon_%26_Co." title="Organon & Co.">Organon</a></li> <li><a href="/wiki/Ovation_Pharmaceuticals" title="Ovation Pharmaceuticals">Ovation</a></li> <li><a href="/wiki/Pfizer" title="Pfizer">Pfizer</a> <ul><li><a href="/wiki/Hospira" title="Hospira">Hospira</a></li> <li><a href="/wiki/G.D._Searle,_LLC" title="G.D. Searle, LLC">Searle</a></li></ul></li> <li><a href="/wiki/PPD,_Inc." title="PPD, Inc.">Pharmaceutical Product Development</a></li> <li><a href="/wiki/Prasco_Laboratories" title="Prasco Laboratories">Prasco Laboratories</a></li> <li><a href="/wiki/Procter_%26_Gamble" title="Procter & Gamble">Procter & Gamble</a></li> <li><a href="/wiki/Proteon_Therapeutics" title="Proteon Therapeutics">Proteon Therapeutics</a></li> <li><a href="/wiki/Purdue_Pharma" title="Purdue Pharma">Purdue Pharma</a></li> <li><a href="/wiki/Quark_Pharmaceuticals" title="Quark Pharmaceuticals">Quark</a></li> <li><a href="/wiki/Regeneron_Pharmaceuticals" title="Regeneron Pharmaceuticals">Regeneron</a></li> <li><a href="/wiki/RespireRx" title="RespireRx">RespireRx</a></li> <li><a href="/wiki/Sarepta_Therapeutics" title="Sarepta Therapeutics">Sarepta Therapeutics</a></li> <li><a href="/wiki/Sheffield_Pharmaceuticals" title="Sheffield Pharmaceuticals">Sheffield</a></li> <li><a href="/wiki/Spectrum_Pharmaceuticals" title="Spectrum Pharmaceuticals">Spectrum</a></li> <li><a href="/wiki/Tec_Laboratories" title="Tec Laboratories">Tec Laboratories</a></li> <li><a href="/wiki/Titan_Pharmaceuticals" title="Titan Pharmaceuticals">Titan</a></li> <li><a href="/wiki/Trevena_Inc" class="mw-redirect" title="Trevena Inc">Trevena Inc</a></li> <li><a href="/wiki/Ultragenyx" title="Ultragenyx">Ultragenyx</a></li> <li><a href="/wiki/Upsher-Smith_Laboratories" title="Upsher-Smith Laboratories">Upsher-Smith</a></li> <li><a href="/wiki/Ventria_Bioscience" title="Ventria Bioscience">Ventria Bioscience</a></li> <li><a href="/wiki/Vertex_Pharmaceuticals" title="Vertex Pharmaceuticals">Vertex</a></li> <li><a href="/wiki/Viatris" title="Viatris">Viatris</a></li> <li><a href="/wiki/West_Pharmaceutical_Services" title="West Pharmaceutical Services">West Pharmaceutical Services</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Former</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th id="Tax_inversion22" scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Tax_inversion" title="Tax inversion">Tax inversion</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Actavis" title="Actavis">Actavis</a> (<a href="/wiki/Corporation_tax_in_the_Republic_of_Ireland#List_of_inversions" title="Corporation tax in the Republic of Ireland">Ireland</a>, 2013)</li> <li><a href="/wiki/Alkermes_(company)" class="mw-redirect" title="Alkermes (company)">Alkermes</a> (<a href="/wiki/Corporation_tax_in_the_Republic_of_Ireland#List_of_inversions" title="Corporation tax in the Republic of Ireland">Ireland</a>, 2011)</li> <li><a href="/wiki/Allergan" title="Allergan">Allergan</a> (<a href="/wiki/Corporation_tax_in_the_Republic_of_Ireland#List_of_inversions" title="Corporation tax in the Republic of Ireland">Ireland</a>, 2015)</li> <li><a href="/wiki/Covidien" title="Covidien">Covidien</a> (<a href="/wiki/Corporation_tax_in_the_Republic_of_Ireland#List_of_inversions" title="Corporation tax in the Republic of Ireland">Ireland</a>, 2007)</li> <li><a href="/wiki/Endo_International" title="Endo International">Endo International</a> (<a href="/wiki/Corporation_tax_in_the_Republic_of_Ireland#List_of_inversions" title="Corporation tax in the Republic of Ireland">Ireland</a>, 2014)</li> <li><a href="/wiki/Horizon_Therapeutics" title="Horizon Therapeutics">Horizon Therapeutics</a> (<a href="/wiki/Corporation_tax_in_the_Republic_of_Ireland#List_of_inversions" title="Corporation tax in the Republic of Ireland">Ireland</a>, 2014)</li> <li><a href="/wiki/Jazz_Pharmaceuticals" title="Jazz Pharmaceuticals">Jazz Pharmaceuticals</a> (<a href="/wiki/Corporation_tax_in_the_Republic_of_Ireland#List_of_inversions" title="Corporation tax in the Republic of Ireland">Ireland</a>, 2012)</li> <li><a href="/wiki/Mallinckrodt" title="Mallinckrodt">Mallinckrodt</a> (<a href="/wiki/Corporation_tax_in_the_Republic_of_Ireland#List_of_inversions" title="Corporation tax in the Republic of Ireland">Ireland</a>, 2013)</li> <li><a href="/wiki/Perrigo" title="Perrigo">Perrigo</a> (<a href="/wiki/Corporation_tax_in_the_Republic_of_Ireland#List_of_inversions" title="Corporation tax in the Republic of Ireland">Ireland</a>, 2013)</li> <li><a href="/wiki/Bausch_Health" title="Bausch Health">Bausch Health</a> (Canada, 2010)</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Other</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Alza" title="Alza">Alza</a></li> <li><a href="/wiki/Allergan,_Inc." title="Allergan, Inc.">Allergan, Inc.</a></li> <li><a href="/wiki/Amylin_Pharmaceuticals" title="Amylin Pharmaceuticals">Amylin</a></li> <li><a href="/wiki/ARIAD_Pharmaceuticals" title="ARIAD Pharmaceuticals">ARIAD</a></li> <li><a href="/wiki/Barr_Pharmaceuticals" title="Barr Pharmaceuticals">Barr</a></li> <li><a href="/wiki/Biolex" title="Biolex">Biolex</a></li> <li><a href="/wiki/Bradley_Pharmaceuticals" title="Bradley Pharmaceuticals">Bradley</a></li> <li><a href="/wiki/CancerVax" title="CancerVax">CancerVax</a></li> <li><a href="/wiki/Cephalon" title="Cephalon">Cephalon</a></li> <li><a href="/wiki/CoTherix" class="mw-redirect" title="CoTherix">CoTherix</a></li> <li><a href="/wiki/Cubist_Pharmaceuticals" title="Cubist Pharmaceuticals">Cubist</a></li> <li><a href="/wiki/Cutter_Laboratories" title="Cutter Laboratories">Cutter Laboratories</a></li> <li><a href="/wiki/DNAPrint_Genomics" title="DNAPrint Genomics">DNAPrint Genomics</a></li> <li><a href="/wiki/Epix_Pharmaceuticals" title="Epix Pharmaceuticals">Epix</a></li> <li><a href="/wiki/Forest_Laboratories" title="Forest Laboratories">Forest Laboratories</a></li> <li><a href="/wiki/Genta_(company)" title="Genta (company)">Genta</a></li> <li><a href="/wiki/ImClone_Systems" title="ImClone Systems">ImClone Systems</a></li> <li><a href="/wiki/ISTA_Pharmaceuticals" title="ISTA Pharmaceuticals">ISTA</a></li> <li><a href="/wiki/King_Pharmaceuticals" title="King Pharmaceuticals">King</a></li> <li><a href="/wiki/KV_Pharmaceutical" title="KV Pharmaceutical">KV</a></li> <li><a href="/wiki/Leiner_Health_Products" title="Leiner Health Products">Leiner Health Products</a></li> <li><a href="/wiki/Martek_Biosciences_Corporation" title="Martek Biosciences Corporation">Martek Biosciences</a></li> <li><a href="/wiki/S._E._Massengill_Company" title="S. E. Massengill Company">Massengill</a></li> <li><a href="/wiki/Miles_Laboratories" title="Miles Laboratories">Miles Laboratories</a></li> <li><a href="/wiki/Mylan" title="Mylan">Mylan</a></li> <li><a href="/wiki/Naurex" class="mw-redirect" title="Naurex">Naurex</a></li> <li><a href="/wiki/Nereus_Pharmaceuticals" title="Nereus Pharmaceuticals">Nereus</a></li> <li><a href="/wiki/Nuvelo" title="Nuvelo">Nuvelo</a></li> <li><a href="/wiki/Ortho_Pharmaceutical" title="Ortho Pharmaceutical">Ortho</a></li> <li><a href="/wiki/OSI_Pharmaceuticals" title="OSI Pharmaceuticals">OSI</a></li> <li><a href="/wiki/Parke-Davis" title="Parke-Davis">Parke-Davis</a></li> <li><a href="/wiki/Repros_Therapeutics" title="Repros Therapeutics">Repros Therapeutics</a></li> <li><a href="/wiki/Qualitest" class="mw-redirect" title="Qualitest">Qualitest</a></li> <li><a href="/wiki/Melinta_Therapeutics" title="Melinta Therapeutics">Rib-X</a></li> <li><a href="/wiki/Schering-Plough" title="Schering-Plough">Schering-Plough</a></li> <li><a href="/wiki/Smith,_Kline_%26_French" title="Smith, Kline & French">Smith, Kline & French</a></li> <li><a href="/wiki/Sterling_Drug" title="Sterling Drug">Sterling Drug</a></li> <li><a href="/wiki/Tanox" title="Tanox">Tanox</a></li> <li><a href="/wiki/TAP_Pharmaceuticals" title="TAP Pharmaceuticals">TAP</a></li> <li><a href="/wiki/Trubion" title="Trubion">Trubion</a></li> <li><a href="/wiki/Upjohn" title="Upjohn">Upjohn</a></li> <li><a href="/wiki/Verus_Pharmaceuticals" title="Verus Pharmaceuticals">Verus</a></li> <li><a href="/wiki/ViroPharma" title="ViroPharma">ViroPharma</a></li> <li><a href="/wiki/Wyeth" title="Wyeth">Wyeth</a></li> <li><a href="/wiki/Zonite_Products_Corporation" title="Zonite Products Corporation">Zonite</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><td class="navbox-abovebelow" colspan="2"><div> <ul><li><a href="/wiki/List_of_pharmaceutical_companies" title="List of pharmaceutical companies">List of pharmaceutical companies</a></li></ul> </div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374" /><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236075235" /></div><div role="navigation" class="navbox" aria-labelledby="Components_of_the_Dow_Jones_Industrial_Average50" style="padding:3px"><table class="nowraplinks mw-collapsible autocollapse navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374" /><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1239400231" /><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:Dow_Jones_Industrial_Average_companies" title="Template:Dow Jones Industrial Average companies"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Dow_Jones_Industrial_Average_companies" title="Template talk:Dow Jones Industrial Average companies"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Dow_Jones_Industrial_Average_companies" title="Special:EditPage/Template:Dow Jones Industrial Average companies"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Components_of_the_Dow_Jones_Industrial_Average50" style="font-size:114%;margin:0 4em">Components of the <a href="/wiki/Dow_Jones_Industrial_Average" title="Dow Jones Industrial Average">Dow Jones Industrial Average</a></div></th></tr><tr><td colspan="2" class="navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/3M" title="3M">3M</a></li> <li><a href="/wiki/Amazon_(company)" title="Amazon (company)">Amazon</a></li> <li><a href="/wiki/American_Express" title="American Express">American Express</a></li> <li><a class="mw-selflink selflink">Amgen</a></li> <li><a href="/wiki/Apple_Inc." title="Apple Inc.">Apple</a></li> <li><a href="/wiki/Boeing" title="Boeing">Boeing</a></li> <li><a href="/wiki/Caterpillar_Inc." title="Caterpillar Inc.">Caterpillar</a></li> <li><a href="/wiki/Chevron_Corporation" title="Chevron Corporation">Chevron</a></li> <li><a href="/wiki/Cisco" title="Cisco">Cisco</a></li> <li><a href="/wiki/The_Coca-Cola_Company" title="The Coca-Cola Company">Coca-Cola</a></li> <li><a href="/wiki/The_Walt_Disney_Company" title="The Walt Disney Company">Disney</a></li> <li><a href="/wiki/Goldman_Sachs" title="Goldman Sachs">Goldman Sachs</a></li> <li><a href="/wiki/Home_Depot" title="Home Depot">Home Depot</a></li> <li><a href="/wiki/Honeywell" title="Honeywell">Honeywell</a></li> <li><a href="/wiki/IBM" title="IBM">IBM</a></li> <li><a href="/wiki/Johnson_%26_Johnson" title="Johnson & Johnson">Johnson & Johnson</a></li> <li><a href="/wiki/JPMorgan_Chase" title="JPMorgan Chase">JPMorgan Chase</a></li> <li><a href="/wiki/McDonald%27s" title="McDonald's">McDonald's</a></li> <li><a href="/wiki/Merck_%26_Co." title="Merck & Co.">Merck</a></li> <li><a href="/wiki/Microsoft" title="Microsoft">Microsoft</a></li> <li><a href="/wiki/Nike,_Inc." title="Nike, Inc.">Nike</a></li> <li><a href="/wiki/Nvidia" title="Nvidia">Nvidia</a></li> <li><a href="/wiki/Procter_%26_Gamble" title="Procter & Gamble">Procter & Gamble</a></li> <li><a href="/wiki/Salesforce" title="Salesforce">Salesforce</a></li> <li><a href="/wiki/Sherwin-Williams" title="Sherwin-Williams">Sherwin-Williams</a></li> <li><a href="/wiki/The_Travelers_Companies" title="The Travelers Companies">Travelers</a></li> <li><a href="/wiki/UnitedHealth_Group" title="UnitedHealth Group">UnitedHealth</a></li> <li><a href="/wiki/Verizon" title="Verizon">Verizon</a></li> <li><a href="/wiki/Visa_Inc." title="Visa Inc.">Visa</a></li> <li><a href="/wiki/Walmart" title="Walmart">Walmart</a></li></ul> </div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374" /><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236075235" /></div><div role="navigation" class="navbox" aria-labelledby="Companies_of_the_Nasdaq-100_index37" style="padding:3px"><table class="nowraplinks mw-collapsible autocollapse navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374" /><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1239400231" /><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:Nasdaq-100" title="Template:Nasdaq-100"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Nasdaq-100" title="Template talk:Nasdaq-100"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Nasdaq-100" title="Special:EditPage/Template:Nasdaq-100"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Companies_of_the_Nasdaq-100_index37" style="font-size:114%;margin:0 4em">Companies of the <a href="/wiki/Nasdaq-100" title="Nasdaq-100">Nasdaq-100</a> index</div></th></tr><tr><td colspan="2" class="navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Adobe_Inc." title="Adobe Inc.">Adobe</a></li> <li><a href="/wiki/ADP_(company)" title="ADP (company)">ADP</a></li> <li><a href="/wiki/AMD" title="AMD">AMD</a></li> <li><a href="/wiki/Airbnb" title="Airbnb">Airbnb</a></li> <li><a href="/wiki/Alphabet_Inc." title="Alphabet Inc.">Alphabet</a></li> <li><a href="/wiki/Amazon_(company)" title="Amazon (company)">Amazon</a></li> <li><a href="/wiki/American_Electric_Power" title="American Electric Power">AEP</a></li> <li><a class="mw-selflink selflink">Amgen</a></li> <li><a href="/wiki/Analog_Devices" title="Analog Devices">Analog Devices</a></li> <li><a href="/wiki/Ansys" title="Ansys">Ansys</a></li> <li><a href="/wiki/Apple_Inc." title="Apple Inc.">Apple</a></li> <li><a href="/wiki/Applied_Materials" title="Applied Materials">Applied Materials</a></li> <li><a href="/wiki/AppLovin" title="AppLovin">AppLovin</a></li> <li><a href="/wiki/Arm_Holdings" title="Arm Holdings">Arm</a></li> <li><a href="/wiki/ASML_Holding" title="ASML Holding">ASML</a></li> <li><a href="/wiki/AstraZeneca" title="AstraZeneca">AstraZeneca</a></li> <li><a href="/wiki/Atlassian" title="Atlassian">Atlassian</a></li> <li><a href="/wiki/Autodesk" title="Autodesk">Autodesk</a></li> <li><a href="/wiki/Axon_Enterprise" title="Axon Enterprise">Axon</a></li> <li><a href="/wiki/Baker_Hughes" title="Baker Hughes">Baker Hughes</a></li> <li><a href="/wiki/Biogen" title="Biogen">Biogen</a></li> <li><a href="/wiki/Booking_Holdings" title="Booking Holdings">Booking Holdings</a></li> <li><a href="/wiki/Broadcom" title="Broadcom">Broadcom</a></li> <li><a href="/wiki/Cadence_Design_Systems" title="Cadence Design Systems">Cadence</a></li> <li><a href="/wiki/CDW" title="CDW">CDW</a></li> <li><a href="/wiki/Charter_Communications" title="Charter Communications">Charter Communications</a></li> <li><a href="/wiki/Cintas" title="Cintas">Cintas</a></li> <li><a href="/wiki/Cisco" title="Cisco">Cisco</a></li> <li><a href="/wiki/Coca-Cola_Europacific_Partners" title="Coca-Cola Europacific Partners">Coca-Cola Europacific Partners</a></li> <li><a href="/wiki/Cognizant" title="Cognizant">Cognizant</a></li> <li><a href="/wiki/Comcast" title="Comcast">Comcast</a></li> <li><a href="/wiki/Constellation_Energy" title="Constellation Energy">Constellation Energy</a></li> <li><a href="/wiki/Copart" title="Copart">Copart</a></li> <li><a href="/wiki/CoStar_Group" title="CoStar Group">CoStar</a></li> <li><a href="/wiki/Costco" title="Costco">Costco</a></li> <li><a href="/wiki/CrowdStrike" title="CrowdStrike">CrowdStrike</a></li> <li><a href="/wiki/CSX_Corporation" title="CSX Corporation">CSX</a></li> <li><a href="/wiki/Datadog" title="Datadog">Datadog</a></li> <li><a href="/wiki/Dexcom" title="Dexcom">Dexcom</a></li> <li><a href="/wiki/Diamondback_Energy" title="Diamondback Energy">Diamondback Energy</a></li> <li><a href="/wiki/DoorDash" title="DoorDash">DoorDash</a></li> <li><a href="/wiki/Electronic_Arts" title="Electronic Arts">Electronic Arts</a></li> <li><a href="/wiki/Exelon" title="Exelon">Exelon</a></li> <li><a href="/wiki/Fastenal" title="Fastenal">Fastenal</a></li> <li><a href="/wiki/Fortinet" title="Fortinet">Fortinet</a></li> <li><a href="/wiki/GE_HealthCare" title="GE HealthCare">GE HealthCare</a></li> <li><a href="/wiki/Gilead_Sciences" title="Gilead Sciences">Gilead</a></li> <li><a href="/wiki/GlobalFoundries" title="GlobalFoundries">GlobalFoundries</a></li> <li><a href="/wiki/Honeywell" title="Honeywell">Honeywell</a></li> <li><a href="/wiki/Idexx_Laboratories" title="Idexx Laboratories">Idexx Laboratories</a></li> <li><a href="/wiki/Intel" title="Intel">Intel</a></li> <li><a href="/wiki/Intuit" title="Intuit">Intuit</a></li> <li><a href="/wiki/Intuitive_Surgical" title="Intuitive Surgical">Intuitive Surgical</a></li> <li><a href="/wiki/Keurig_Dr_Pepper" title="Keurig Dr Pepper">Keurig Dr Pepper</a></li> <li><a href="/wiki/KLA_Corporation" title="KLA Corporation">KLA</a></li> <li><a href="/wiki/Kraft_Heinz" title="Kraft Heinz">Kraft Heinz</a></li> <li><a href="/wiki/Lam_Research" title="Lam Research">Lam Research</a></li> <li><a href="/wiki/Linde_plc" title="Linde plc">Linde</a></li> <li><a href="/wiki/Lululemon_Athletica" class="mw-redirect" title="Lululemon Athletica">Lululemon</a></li> <li><a href="/wiki/Marriott_International" title="Marriott International">Marriott International</a></li> <li><a href="/wiki/Marvell_Technology" title="Marvell Technology">Marvell</a></li> <li><a href="/wiki/Mercado_Libre" title="Mercado Libre">Mercado Libre</a></li> <li><a href="/wiki/Meta_Platforms" title="Meta Platforms">Meta</a></li> <li><a href="/wiki/Microchip_Technology" title="Microchip Technology">Microchip</a></li> <li><a href="/wiki/Micron_Technology" title="Micron Technology">Micron</a></li> <li><a href="/wiki/Microsoft" title="Microsoft">Microsoft</a></li> <li><a href="/wiki/MicroStrategy" title="MicroStrategy">MicroStrategy</a></li> <li><a href="/wiki/Mondelez_International" title="Mondelez International">Mondelez International</a></li> <li><a href="/wiki/MongoDB_Inc." title="MongoDB Inc.">MongoDB</a></li> <li><a href="/wiki/Monster_Beverage" title="Monster Beverage">Monster Beverage</a></li> <li><a href="/wiki/Netflix,_Inc." title="Netflix, Inc.">Netflix</a></li> <li><a href="/wiki/Nvidia" title="Nvidia">Nvidia</a></li> <li><a href="/wiki/NXP_Semiconductors" title="NXP Semiconductors">NXP</a></li> <li><a href="/wiki/O%27Reilly_Auto_Parts" title="O'Reilly Auto Parts">O'Reilly Auto Parts</a></li> <li><a href="/wiki/Old_Dominion_Freight_Line" title="Old Dominion Freight Line">Old Dominion</a></li> <li><a href="/wiki/Onsemi" title="Onsemi">onsemi</a></li> <li><a href="/wiki/Paccar" title="Paccar">Paccar</a></li> <li><a href="/wiki/Palantir_Technologies" title="Palantir Technologies">Palantir</a></li> <li><a href="/wiki/Palo_Alto_Networks" title="Palo Alto Networks">Palo Alto Networks</a></li> <li><a href="/wiki/Paychex" title="Paychex">Paychex</a></li> <li><a href="/wiki/PayPal" title="PayPal">PayPal</a></li> <li><a href="/wiki/Pinduoduo" title="Pinduoduo">PDD Holdings</a></li> <li><a href="/wiki/PepsiCo" title="PepsiCo">PepsiCo</a></li> <li><a href="/wiki/Qualcomm" title="Qualcomm">Qualcomm</a></li> <li><a href="/wiki/Regeneron_Pharmaceuticals" title="Regeneron Pharmaceuticals">Regeneron</a></li> <li><a href="/wiki/Roper_Technologies" title="Roper Technologies">Roper Technologies</a></li> <li><a href="/wiki/Ross_Stores" title="Ross Stores">Ross Stores</a></li> <li><a href="/wiki/Starbucks" title="Starbucks">Starbucks</a></li> <li><a href="/wiki/Synopsys" title="Synopsys">Synopsys</a></li> <li><a href="/wiki/Take-Two_Interactive" title="Take-Two Interactive">Take-Two Interactive</a></li> <li><a href="/wiki/T-Mobile_US" title="T-Mobile US">T-Mobile US</a></li> <li><a href="/wiki/Tesla,_Inc." title="Tesla, Inc.">Tesla</a></li> <li><a href="/wiki/Texas_Instruments" title="Texas Instruments">Texas Instruments</a></li> <li><a href="/wiki/The_Trade_Desk" title="The Trade Desk">Trade Desk</a></li> <li><a href="/wiki/Verisk_Analytics" title="Verisk Analytics">Verisk</a></li> <li><a href="/wiki/Vertex_Pharmaceuticals" title="Vertex Pharmaceuticals">Vertex</a></li> <li><a href="/wiki/Warner_Bros._Discovery" title="Warner Bros. Discovery">Warner Bros. Discovery</a></li> <li><a href="/wiki/Workday,_Inc." title="Workday, Inc.">Workday</a></li> <li><a href="/wiki/Xcel_Energy" title="Xcel Energy">Xcel Energy</a></li> <li><a href="/wiki/Zscaler" title="Zscaler">Zscaler</a></li></ul> </div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374" /><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236075235" /></div><div role="navigation" class="navbox authority-control" aria-labelledby="Authority_control_databases_frameless&#124;text-top&#124;10px&#124;alt=Edit_this_at_Wikidata&#124;link=https&#58;//www.wikidata.org/wiki/Q470517#identifiers&#124;class=noprint&#124;Edit_this_at_Wikidata676" style="padding:3px"><table class="nowraplinks hlist mw-collapsible autocollapse navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><div 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/></a></div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%">International</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><ul><li><a rel="nofollow" class="external text" href="https://isni.org/isni/0000000106575612">ISNI</a></li><li><a rel="nofollow" class="external text" href="https://viaf.org/viaf/125944315">VIAF</a></li></ul></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">National</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"><ul><li><a rel="nofollow" class="external text" href="https://id.loc.gov/authorities/nr94015151">United States</a></li><li><a rel="nofollow" class="external text" href="https://www.nli.org.il/en/authorities/987007605084405171">Israel</a></li></ul></div></td></tr></tbody></table></div>    </div><noscript><img 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