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href="javascript:;" id="mobile_nav_icon"><span class="ti-menu"></span></a>  </div>  </div>  </div> </div> </div> </div> </div> <div id="page_caption" class=" "> <div class="page_title_wrapper"> <div class="standard_wrapper"> <div class="page_title_inner"> <div class="page_title_content"> <h1>The Blog</h1> </div> </div> </div> </div> </div>  <div id="page_content_wrapper" class=""> <div class="inner">  <div class="inner_wrapper"> <div class="sidebar_content">  <div id="post-7862" class="post-7862 post type-post status-publish format-standard has-post-thumbnail hentry category-abbotttalks tag-abbott tag-abbotttalks tag-cardiology tag-cardiovascular tag-devicetalks tag-fda-approval tag-innovation tag-interviews tag-leadership tag-medical-device tag-medical-technology tag-medtech tag-podcast tag-product-development tag-women-in-medtech"> <div class="post_wrapper"> <div class="post_content_wrapper"> <h1>Abbott’s Jones-McMeans and Dr. DeRubertis on PAD below-the-knee, LIFE-BTK trial and Esprit BTK approval</h1> <div class="post_detail single_post"> <span class="post_info_date"> September 17, 2024 </span> <span class="post_info_comment"> • 0 Comment </span> </div> <div class="post_img static"> <img src="https://www.devicetalks.com/wp-content/uploads/2024/09/AbbottTalks_9.17.24_1200x800_MAIN_Vs1-960x636.png" alt="" class="" /> </div> <div class="addtoany_share_save_container addtoany_content addtoany_content_top"><div class="a2a_kit a2a_kit_size_16 addtoany_list" data-a2a-url="https://www.devicetalks.com/abbotts-jones-mcmeans-and-dr-derubertis-on-pad-below-the-knee-life-btk-trial-and-esprit-btk-approval/" data-a2a-title="Abbott’s Jones-McMeans and Dr. DeRubertis on PAD below-the-knee, LIFE-BTK trial and Esprit BTK approval"><a class="a2a_button_facebook" href="https://www.addtoany.com/add_to/facebook?linkurl=https%3A%2F%2Fwww.devicetalks.com%2Fabbotts-jones-mcmeans-and-dr-derubertis-on-pad-below-the-knee-life-btk-trial-and-esprit-btk-approval%2F&linkname=Abbott%E2%80%99s%20Jones-McMeans%20and%20Dr.%20DeRubertis%20on%20PAD%20below-the-knee%2C%20LIFE-BTK%20trial%20and%20Esprit%20BTK%20approval" title="Facebook" rel="nofollow noopener" target="_blank"></a><a class="a2a_button_twitter" href="https://www.addtoany.com/add_to/twitter?linkurl=https%3A%2F%2Fwww.devicetalks.com%2Fabbotts-jones-mcmeans-and-dr-derubertis-on-pad-below-the-knee-life-btk-trial-and-esprit-btk-approval%2F&linkname=Abbott%E2%80%99s%20Jones-McMeans%20and%20Dr.%20DeRubertis%20on%20PAD%20below-the-knee%2C%20LIFE-BTK%20trial%20and%20Esprit%20BTK%20approval" title="Twitter" rel="nofollow noopener" target="_blank"></a><a class="a2a_button_linkedin" href="https://www.addtoany.com/add_to/linkedin?linkurl=https%3A%2F%2Fwww.devicetalks.com%2Fabbotts-jones-mcmeans-and-dr-derubertis-on-pad-below-the-knee-life-btk-trial-and-esprit-btk-approval%2F&linkname=Abbott%E2%80%99s%20Jones-McMeans%20and%20Dr.%20DeRubertis%20on%20PAD%20below-the-knee%2C%20LIFE-BTK%20trial%20and%20Esprit%20BTK%20approval" title="LinkedIn" rel="nofollow noopener" target="_blank"></a><a class="a2a_dd addtoany_share_save addtoany_share" href="https://www.addtoany.com/share"><img src="https://static.addtoany.com/buttons/favicon.png" alt="Share"></a></div></div><p><span style="font-weight: 400;">In this episode of AbbottTalks, Jennifer Jones-McMeans, PhD, Divisional VP of Global Clinical Affairs at Abbott and </span><span style="font-weight: 400;">Brian DeRubertis, MD, Chief, Division of Vascular & Endovascular Surgery at </span><span style="font-weight: 400;">Weill Cornell Medical Center</span><span style="font-weight: 400;"> tackle the complexities of treating peripheral arterial disease (PAD) below the knee, particularly chronic limb-threatening ischemia (CLTI), a severe form of PAD that drastically impacts patients’ quality of life and longevity.</span></p> <p><span style="font-weight: 400;">In the episode, the two discuss Abbott’s Esprit BTK System, the first-and-only FDA-approved drug-eluting resorbable scaffold for infrapopliteal CLTI. Dr. Jones-McMeans explains how Esprit BTK works by releasing a drug that prevents artery re-narrowing, crucial for maintaining sustained blood flow and promoting wound healing. </span></p> <p><span style="font-weight: 400;">Later, they walk us through the pivotal LIFE-BTK trial, a significant milestone that demonstrated Esprit’s efficacy and led to its FDA approval. They also highlight the importance of including diverse patient populations in clinical trials, particularly those disproportionately affected by PAD, such as African Americans, Latinos, Native Americans, and women. This inclusive approach not only ensures the treatment’s effectiveness across varied demographics but also sets a precedent for future trials.</span></p> <p><span style="font-weight: 400;">Thank you to <a href="http://www.freudenbergmedical.com" target="_blank" rel="noopener">Freudenberg Medical</a> for sponsoring this episode of AbbottTalks. For more information on how Freudenberg Medical works with medical device companies, visit www.freudenbergmedical.com.</span></p> <p><span style="font-weight: 400;">Thank you for listening to the AbbottTalks Podcast. Tune in and subscribe to DeviceTalks on all major podcast channels to never miss an episode.</span></p> <p><iframe src="https://w.soundcloud.com/player/?url=https%3A//api.soundcloud.com/tracks/1918332053&color=%23ff5500&auto_play=false&hide_related=false&show_comments=true&show_user=true&show_reposts=false&show_teaser=true&visual=true" width="100%" height="300" frameborder="no" scrolling="no"></iframe></p> <div style="font-size: 10px; color: #cccccc; line-break: anywhere; word-break: normal; overflow: hidden; white-space: nowrap; text-overflow: ellipsis; font-family: Interstate,Lucida Grande,Lucida Sans Unicode,Lucida Sans,Garuda,Verdana,Tahoma,sans-serif; font-weight: 100;"><a style="color: #cccccc; text-decoration: none;" title="DeviceTalks" href="https://soundcloud.com/devicetalks" target="_blank" rel="noopener">DeviceTalks</a> · <a style="color: #cccccc; text-decoration: none;" title="Abbott’s Jones-McMeans and Dr DeRubertis on PAD below-the-knee, LIFE-BTK trial & Esprit BTK approval" href="https://soundcloud.com/devicetalks/abbotts-jones-mcmeans-and-dr-derubertis-on-pad-below-the-knee-life-btk-trial-esprit-btk-approval" target="_blank" rel="noopener">Abbott’s Jones-McMeans and Dr DeRubertis on PAD below-the-knee, LIFE-BTK trial & Esprit BTK approval</a></div> <div class="post_excerpt post_tag"> <a href="https://www.devicetalks.com/tag/abbott/">#Abbott</a><a href="https://www.devicetalks.com/tag/abbotttalks/">#AbbottTalks</a><a href="https://www.devicetalks.com/tag/cardiology/">#Cardiology</a><a href="https://www.devicetalks.com/tag/cardiovascular/">#cardiovascular</a><a href="https://www.devicetalks.com/tag/devicetalks/">#DeviceTalks</a><a href="https://www.devicetalks.com/tag/fda-approval/">#FDA Approval</a><a href="https://www.devicetalks.com/tag/innovation/">#Innovation</a><a href="https://www.devicetalks.com/tag/interviews/">#Interviews</a><a href="https://www.devicetalks.com/tag/leadership/">#Leadership</a><a 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