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ATTRv Amyloidosis Hub | Resources to understand how Alnylam’s RNAi-based medicines work
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in</a> </li> </ul> </nav> <span class="menu-separator">|</span> <nav class="signup-menu-wrapper"> <ul class="al-menu-signup menu"> <li class="menu-item"> <a href="/user/register" data-drupal-link-system-path="user/register">Sign Up</a> </li> </ul> </nav> </div> </div> </div> </nav> </div> <div class="row"> <div class="top-content col-12"> <div class="region region-content"> <div id="block-alnylam-breadcrumbs" class="block block-system block-system-breadcrumb-block"> </div> <div id="block-alnylam-content" class="block block-system block-system-main-block"> <article about="/attrv-amyloidosis-hub" class="node node--type-generic node--promoted node--view-mode-full"> <div class="node__content"> <h1><span class="field field--name-title field--type-string field--label-hidden">ATTRv Amyloidosis Hub</span> </h1> <div class="meta"> <div class="date-keywords"> <div class="posted-by"> <span class="posted-date">Posted: August 05, 2024</span> </div> <div class="keywords"> Keywords: <div class="field field--name-field-generic-keywords field--type-entity-reference field--label-hidden field__items"> <div class="field__item"> <a href="/search?query=amyloidosis">amyloidosis</a> </div> <div class="field__item"> <a href="/search?query=ATTRv">ATTRv</a> </div> <div class="field__item"> <a href="/search?query=diagnosis">diagnosis</a> </div> <div class="field__item"> <a href="/search?query=hATTR">hATTR</a> </div> </div> </div> </div> <div class="bookmark-share-widgets full content-131"> <div class="block block-social-media block-social-sharing-block"> <div class="sharing"> <a class="icon" tabindex="0"> <img src="/themes/custom/alnylam/assets/dist/images/share.svg" class="desktop" alt="Share this page on social media"> <img src="/themes/custom/alnylam/assets/dist/images/share-mobile.svg" class="mobile" alt="Share this page on social media"> </a> <div class="socials"> <a class="copy-link" tabindex="0" data-copy-link=https://www.rnaiscience.com/attrv-amyloidosis-hub> <img src="/themes/custom/alnylam/assets/dist/images/copy-link.svg" class="share-image" alt="Copy a link to this page">Copy Link<span class="copied-message">Copied!</span> </a> </div> </div> </div> <div class="bookmarks no-auth force-auth"><a id="bookmark-login"><img src="/themes/custom/alnylam/assets/dist/images/bookmark.svg" class="desktop" alt="Bookmark this page"><img src="/themes/custom/alnylam/assets/dist/images/bookmark-mobile.svg" class="mobile" alt="Bookmark this page"></a></div> </div> </div> <div class="field field--name-field-modules field--type-entity-reference-revisions field--label-hidden field__items"> <div class="bundle-full-width-image field__item"> <div class="hero paragraph paragraph--type--full-width-image paragraph--view-mode--default"> <div class="full-width-image"> <div class="image"> <div class="desktop"> <img src="https://www.rnaiscience.com/sites/default/files/styles/webp/public/2024-08/PRIME%20logo_0.png.webp?itok=ClZsRRn2" alt="Prime Logo" loading="lazy"> </div> <div class="mobile"> <img src="https://www.rnaiscience.com/sites/default/files/styles/webp/public/2024-08/Prime-Logo.png.webp?itok=SPCD03Go" alt="Prime Logo" loading="lazy"> </div> </div> </div> </div> </div> <div class="bundle-general-text-section field__item"> <div class="general-text-section paragraph paragraph--type--general-text-section paragraph--view-mode--default color--default"> <div class="clearfix text-formatted field field--name-field-general-text-section-text field--type-text-with-summary field--label-hidden field__item"><p>This Resource Center, provided by PRIME Education and supported by Alnylam Pharmaceuticals, contains downloadable resources and practical tools to support coordinated, multidisciplinary care and facilitate timely, comprehensive diagnostic evaluations for patients with ATTRv (also known as hATTR) amyloidosis.</p></div> </div> </div> <div class="bundle-general-text-section field__item"> <div class="general-text-section paragraph paragraph--type--general-text-section paragraph--view-mode--default color--default"> <div class="clearfix text-formatted field field--name-field-general-text-section-text field--type-text-with-summary field--label-hidden field__item"><p><a href="https://primeinc.org/resourcecenter/attrv-amyloidosis-hub" target="_blank">ATTRv Amyloidosis Hub</a></p></div> </div> </div> <div class="bundle-left-image-right-text field__item"> <div class="paragraph paragraph--type--left-image-right-text paragraph--view-mode--default"> <div class="left"> <div class="field field--name-field-left-image field--type-entity-reference field--label-hidden field__item"><article class="media media--type-image media--view-mode-default"> <div class="field field--name-field-media-image field--type-image field--label-visually_hidden"> <div class="field__label visually-hidden">Image</div> <div class="field__item"> <img loading="lazy" class="no-image-style image-style-webp" src="/sites/default/files/2024-08/iconizer-ATTR_Playbook.svg" alt="ATTR Playbook" typeof="foaf:Image" /> </div> </div> </article> </div> </div> <div class="right"> <div class="clearfix text-formatted field field--name-field-right-text field--type-text-long field--label-hidden field__item"><h3><a href="https://primeinc.org/resourcecenter/attrv-amyloidosis-hub" target="_blank">Performance Improvement Playbook</a></h3><p>The goal of the ATTRv Amyloidosis Performance Improvement Playbook (“Playbook”) is to provide clinicians with practical tools to improve the delivery of comprehensive, collaborative care that meets the individual needs of patients with ATTRv amyloidosis. The Playbook offers insights and resources informed by a nationwide quality improvement (QI) initiative and curated to address four major barriers that can inhibit comprehensive care and improved outcomes for patients with ATTRv amyloidosis: 1) delayed diagnosis; 2) incomplete diagnostic workups; 3) lack of shared decision-making with patients; and 4) insufficient follow-up to monitor for disease progression.</p></div> </div> </div> </div> <div class="bundle-left-image-right-text field__item"> <div class="paragraph paragraph--type--left-image-right-text paragraph--view-mode--default"> <div class="left"> <div class="field field--name-field-left-image field--type-entity-reference field--label-hidden field__item"><article class="media media--type-image media--view-mode-default"> <div class="field field--name-field-media-image field--type-image field--label-visually_hidden"> <div class="field__label visually-hidden">Image</div> <div class="field__item"> <img loading="lazy" class="no-image-style image-style-webp" src="/sites/default/files/2024-08/ATTR_Disease%20Awareness.svg" alt="Disease Awareness" typeof="foaf:Image" /> </div> </div> </article> </div> </div> <div class="right"> <div class="clearfix text-formatted field field--name-field-right-text field--type-text-long field--label-hidden field__item"><h3><a href="https://primeinc.org/resourcecenter/attrv-amyloidosis-disease-awareness" target="_blank">Disease Awareness</a></h3><p>ATTRv amyloidosis is an underrecognized multisystemic disease that presents with varying signs and symptoms often misattributed to other conditions. This Resource Center contains tools to elevate awareness of ATTRv amyloidosis in your community.</p></div> </div> </div> </div> <div class="bundle-left-image-right-text field__item"> <div class="paragraph paragraph--type--left-image-right-text paragraph--view-mode--default"> <div class="left"> <div class="field field--name-field-left-image field--type-entity-reference field--label-hidden field__item"><article class="media media--type-image media--view-mode-default"> <div class="field field--name-field-media-image field--type-image field--label-visually_hidden"> <div class="field__label visually-hidden">Image</div> <div class="field__item"> <img loading="lazy" class="no-image-style image-style-webp" src="/sites/default/files/2024-08/iconizer-ATTR_Diagnosis.svg" alt="Diagnosis" typeof="foaf:Image" /> </div> </div> </article> </div> </div> <div class="right"> <div class="clearfix text-formatted field field--name-field-right-text field--type-text-long field--label-hidden field__item"><h3><a href="https://primeinc.org/resourcecenter/attrv-amyloidosis-diagnosis" target="_blank">Diagnosis</a></h3><p>This Resource Center offers tools to assist you in the comprehensive evaluation and diagnosis of ATTRv amyloidosis with cardiomyopathy and/or polyneuropathy.</p></div> </div> </div> </div> <div class="bundle-left-image-right-text field__item"> <div class="paragraph paragraph--type--left-image-right-text paragraph--view-mode--default"> <div class="left"> <div class="field field--name-field-left-image field--type-entity-reference field--label-hidden field__item"><article class="media media--type-image media--view-mode-default"> <div class="field field--name-field-media-image field--type-image field--label-visually_hidden"> <div class="field__label visually-hidden">Image</div> <div class="field__item"> <img loading="lazy" src="/sites/default/files/styles/webp/public/2024-08/Shared-Decision-Making.png.webp?itok=bMX0CZMt" width="392" height="338" alt="Shared Decision Making" typeof="foaf:Image" class="image-style-webp" /> </div> </div> </article> </div> </div> <div class="right"> <div class="clearfix text-formatted field field--name-field-right-text field--type-text-long field--label-hidden field__item"><h3><a href="https://primeinc.org/resourcecenter/attrv-amyloidosis-shared-decision-making" target="_blank">Shared Decision-Making</a></h3><p>ATTRv amyloidosis is a complex condition impacting every aspect of a patient's life. Patient-centered, coordinated care is therefore essential for ensuring clinical, personal, and social needs are addressed. This Resource Center offers tools to help prepare you and your patients for holistic discussions that ensure care decisions align with both clinical goals and individual needs and preferences.</p></div> </div> </div> </div> <div class="bundle-left-image-right-text field__item"> <div class="paragraph paragraph--type--left-image-right-text paragraph--view-mode--default"> <div class="left"> <div class="field field--name-field-left-image field--type-entity-reference field--label-hidden field__item"><article class="media media--type-image media--view-mode-default"> <div class="field field--name-field-media-image field--type-image field--label-visually_hidden"> <div class="field__label visually-hidden">Image</div> <div class="field__item"> <img loading="lazy" class="no-image-style image-style-webp" src="/sites/default/files/2024-08/iconizer-ATTR_Disease_Progression.svg" alt="Disease Progression" typeof="foaf:Image" /> </div> </div> </article> </div> </div> <div class="right"> <div class="clearfix text-formatted field field--name-field-right-text field--type-text-long field--label-hidden field__item"><h3><a href="https://primeinc.org/resourcecenter/attrv-amyloidosis-disease-progression" target="_blank">Disease Progression</a></h3><p>This Resource Center offers tools to help you and your team monitor patients for clinical deterioration and disease progression to inform treatment decisions.</p></div> </div> </div> </div> <div class="bundle-left-image-right-text field__item"> <div class="paragraph paragraph--type--left-image-right-text paragraph--view-mode--default"> <div class="left"> <div class="field field--name-field-left-image field--type-entity-reference field--label-hidden field__item"><article class="media media--type-image media--view-mode-default"> <div class="field field--name-field-media-image field--type-image field--label-visually_hidden"> <div class="field__label visually-hidden">Image</div> <div class="field__item"> <img loading="lazy" class="no-image-style image-style-webp" src="/sites/default/files/2024-08/iconizer-download-svgrepo-com.svg" alt="Downloadable Resources" typeof="foaf:Image" /> </div> </div> </article> </div> </div> <div class="right"> <div class="clearfix text-formatted field field--name-field-right-text field--type-text-long field--label-hidden field__item"><h3><a href="https://primeinc.org/resourcecenter/attrv-amyloidosis-hub#:~:text=START-,DOWNLOADABLE%20RESOURCES,-ATTRV%20AMYLOIDOSIS%20101" target="_blank">Downloadable Resources</a></h3><p>The Performance Improvement Playbook contains many downloadable resources, including but not limited to:</p><ul><li>ATTRv Amyloidosis Disease Progression Checklist</li><li>ATTRv Amyloidosis Pocket Cards</li><li>ATTRv Amyloidosis Shared Decision-Making Guide</li><li>ATTRv Amyloidosis Diagnosis Algorithms</li><li>Cascade Screening and Referral Letters</li><li>Sample EHR Order Sets</li></ul></div> </div> </div> </div> <div class="bundle-general-text-section field__item"> <div class="general-text-section paragraph paragraph--type--general-text-section paragraph--view-mode--default color--default"> <div class="clearfix text-formatted field field--name-field-general-text-section-text field--type-text-with-summary field--label-hidden field__item"><p>This content was developed by a third-party. 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