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<header class="mw-body-header vector-page-titlebar"> <nav aria-label="Indice" class="vector-toc-landmark"> <div id="vector-page-titlebar-toc" class="vector-dropdown vector-page-titlebar-toc vector-button-flush-left" title="Indice" > <input type="checkbox" id="vector-page-titlebar-toc-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-titlebar-toc" class="vector-dropdown-checkbox " aria-label="Mostra/Nascondi l'indice" > <label id="vector-page-titlebar-toc-label" for="vector-page-titlebar-toc-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-listBullet mw-ui-icon-wikimedia-listBullet"></span> <span class="vector-dropdown-label-text">Mostra/Nascondi l'indice</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-titlebar-toc-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <h1 id="firstHeading" class="firstHeading mw-first-heading"><span class="mw-page-title-main">(S)-2-idrossiacido ossidasi</span></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" > <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="Vai a una voce in un'altra lingua. 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color:#000;">(S)-2-idrossiacido ossidasi</th></tr><tr><td class="sinottico_testo_centrale" colspan="2"><span typeof="mw:File"><a href="/wiki/File:2rdw.jpg" class="mw-file-description" title="Modello tridimensionale dell'enzima"><img alt="Modello tridimensionale dell'enzima" src="//upload.wikimedia.org/wikipedia/commons/thumb/f/fa/2rdw.jpg/220px-2rdw.jpg" decoding="async" width="220" height="175" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/f/fa/2rdw.jpg/330px-2rdw.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/f/fa/2rdw.jpg/440px-2rdw.jpg 2x" data-file-width="1000" data-file-height="797" /></a></span><br /><small>Glycolate oxidase tetramer, Human</small></td></tr><tr><th><a href="/wiki/Classificazione_EC" title="Classificazione EC">Numero EC</a></th><td>1.1.3.15 </td></tr><tr><th>Classe</th><td><a href="/wiki/Ossidoreduttasi" title="Ossidoreduttasi">Ossidoreduttasi</a> </td></tr><tr class="sinottico_divisione"><th colspan="2">Nome sistematico</th></tr><tr><td class="sinottico_testo_centrale" colspan="2">(<i>S</i>)-2-idrossiacido:ossigeno 2-ossidoreduttasi </td></tr><tr class="sinottico_divisione"><th colspan="2">Altri nomi</th></tr><tr><td class="sinottico_testo_centrale" colspan="2">glicolato ossidasi; idrossiacido ossidasi A; idrossiacido ossidasi B; <small>L</small>-α-idrossiacido ossidasi; <small>L</small>-2-idrossiacido ossidasi </td></tr><tr><th>Banche dati</th><td><a rel="nofollow" class="external text" href="http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.3.15">BRENDA</a>, <a rel="nofollow" class="external text" href="http://enzyme.expasy.org/EC/1.1.3.15">EXPASY</a>, <a rel="nofollow" class="external text" href="http://xpdb.nist.gov/enzyme_thermodynamics/enzyme_compose_query.pl?EC=1.1.3.15">GTD</a>, PDB (<a rel="nofollow" class="external text" href="https://www.rcsb.org/search?q=rcsb_polymer_entity.rcsb_ec_lineage.id:1.1.3.15">RCSB PDB</a> <a rel="nofollow" class="external text" href="https://www.ebi.ac.uk/pdbe/entry/search/index?ec_number:1.1.3.15">PDBe</a> <a rel="nofollow" class="external text" href="https://pdbj.org/mine/sql?query=SELECT+DISTINCT+pdbid+FROM+entity+WHERE+entity.pdbx_ec%3D%271.1.3.15%27">PDBj</a> <a rel="nofollow" class="external text" href="https://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/enzymes/GetPage.pl?ec_number=1.1.3.15">PDBsum</a>) </td></tr><tr><td colspan="2" class="sinottico_piede" style="background:#FFC253; color:#000;">Fonte: <a rel="nofollow" class="external text" href="http://www.enzyme-database.org/query.php?ec=1.1.3.15">IUBMB</a> </td></tr><tr><td class="sinottico_piede2 noprint nomobile metadata" colspan="2"><a href="https://www.wikidata.org/wiki/Q2813715" class="extiw" title="d:Q2813715"><span title="Modifica i dati della voce (S)-2-idrossiacido ossidasi su Wikidata">Modifica dati su Wikidata</span></a><b> ·</b> <a href="/wiki/Template:Enzima/man" title="Template:Enzima/man"><span title="Manuale del template Enzima">Manuale</span></a></td></tr></tbody></table> <p>La <b>(S)-2-idrossiacido ossidasi</b> è un <a href="/wiki/Enzima" title="Enzima">enzima</a> appartenente alla classe delle <a href="/wiki/Ossidoreduttasi" title="Ossidoreduttasi">ossidoreduttasi</a>, che catalizza la seguente <a href="/wiki/Reazione_chimica" title="Reazione chimica">reazione</a>: </p> <dl><dd>(<i>S</i>)-2-<a href="/w/index.php?title=Idrossiacido&action=edit&redlink=1" class="new" title="Idrossiacido (la pagina non esiste)">idrossiacido</a> + O<sub>2</sub> <style data-mw-deduplicate="TemplateStyles:r107150125">.mw-parser-output .Unicode{font-family:TITUS Cyberbit Basic,Code2000,Doulos SIL,Chrysanthi Unicode,Bitstream Cyberbit,Bitstream CyberBase,Bitstream Vera,Thryomanes,Gentium,GentiumAlt,Visual Geez Unicode,Lucida Grande,Arial Unicode MS,Microsoft Sans Serif,Lucida Sans Unicode;font-family:inherit}</style><span class="Unicode" style="font-family:Antinoou, Code2000, Code2001, TITUS Cyberbit Basic, Doulos SIL, Chrysanthi Unicode, Arial Unicode MS, Bitstream Cyberbit, Bitstream Vera, Gentium, GentiumAlt, Lucida Sans Unicode, Noto Sans Mandaic, Penuturesu, Segoe UI Symbol; font-family :inherit;">⇄</span> 2-<a href="/wiki/Ossoacido" class="mw-redirect" title="Ossoacido">ossoacido</a> + H<sub>2</sub>O<sub>2</sub></dd></dl> <p>L'enzima è una <a href="/wiki/Flavoproteina" class="mw-redirect" title="Flavoproteina">flavoproteina</a> contenente <a href="/wiki/Flavina_mononucleotide" title="Flavina mononucleotide">FMN</a>, esistente in due tipi diversi di <a href="/wiki/Isoenzima" title="Isoenzima">isoenzima</a>. La forma A ossida preferenzialmente gli idrossiacidi che presentano catene alifatiche brevi (ed è stata precedentemente classificata con il nome di <b>glicolato ossidasi</b> e la classificazione EC 1.1.3.1). La forma B ossida invece preferenzialmente idrossiacidi a catena lunga o <a href="/wiki/Composti_aromatici" title="Composti aromatici">aromatica</a>. L'isoenzima presente nel <a href="/wiki/Ratto" class="mw-redirect" title="Ratto">ratto</a> agisce anche come una <a href="/wiki/L-amminoacido_ossidasi" title="L-amminoacido ossidasi"><small>L</small>-amminoacido ossidasi</a>. </p> <div class="mw-heading mw-heading2"><h2 id="Bibliografia">Bibliografia</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=(S)-2-idrossiacido_ossidasi&veaction=edit&section=1" title="Modifica la sezione Bibliografia" class="mw-editsection-visualeditor"><span>modifica</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=(S)-2-idrossiacido_ossidasi&action=edit&section=1" title="Edit section's source code: Bibliografia"><span>modifica wikitesto</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><cite class="citation pubblicazione" style="font-style:normal">(<span style="font-weight:bolder; font-size:80%"><abbr title="inglese">EN</abbr></span>) M. Blanchard, D.E. Green, V. Nocito-Carroll e S. Ratner, <a rel="nofollow" class="external text" href="https://linkinghub.elsevier.com/retrieve/pii/S0021925817413536"><span style="font-style:italic;">l-HYDROXY ACID OXIDASE</span></a>, in <span style="font-style:italic;">Journal of Biological Chemistry</span>, vol. 163, n. 1, 1946, pp. 137-144, <a href="/wiki/Digital_object_identifier" title="Digital object identifier">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1016%2FS0021-9258%2817%2941353-6">10.1016/S0021-9258(17)41353-6</a>. <small>URL consultato il 1º febbraio 2023</small>.</cite></li> <li><cite class="citation pubblicazione" style="font-style:normal">(<span style="font-weight:bolder; font-size:80%"><abbr title="inglese">EN</abbr></span>) N. A. Frigerio e H. A. Harbury, <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/13538955"><span style="font-style:italic;">Preparation and some properties of crystalline glycolic acid oxidase of spinach</span></a>, in <span style="font-style:italic;">The Journal of Biological Chemistry</span>, vol. 231, n. 1, marzo 1958, pp. 135-157, <a href="/wiki/PMID" title="PMID">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/13538955">13538955</a>. <small>URL consultato il 1º febbraio 2023</small>.</cite></li> <li><cite class="citation pubblicazione" style="font-style:normal"> E. Kun, J. M. Dechary e H. C. Pitot, <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/13201588"><span style="font-style:italic;">The oxidation of glycolic acid by a liver enzyme</span></a>, in <span style="font-style:italic;">The Journal of Biological Chemistry</span>, vol. 210, n. 1, settembre 1954, pp. 269-280, <a href="/wiki/PMID" title="PMID">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/13201588">13201588</a>. <small>URL consultato il 1º febbraio 2023</small>.</cite></li> <li><cite class="citation pubblicazione" style="font-style:normal">(<span style="font-weight:bolder; font-size:80%"><abbr title="inglese">EN</abbr></span>) M. Nakano e T. S. Danowski, <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/5946631"><span style="font-style:italic;">Crystalline mammalian L-amino acid oxidase from rat kidney mitochondria</span></a>, in <span style="font-style:italic;">The Journal of Biological Chemistry</span>, vol. 241, n. 9, 10 maggio 1966, pp. 2075-2083, <a href="/wiki/PMID" title="PMID">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/5946631">5946631</a>. <small>URL consultato il 1º febbraio 2023</small>.</cite></li> <li><cite class="citation pubblicazione" style="font-style:normal">(<span style="font-weight:bolder; font-size:80%"><abbr title="inglese">EN</abbr></span>) M. Nakano, Y. Ushijima, M. Saga, Y. Tsutsumi e H. Asami, <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/5686300"><span style="font-style:italic;">Aliphatic L-alpha-hydroxyacid oxidase from rat livers: purification and properties</span></a>, in <span style="font-style:italic;">Biochimica Et Biophysica Acta</span>, vol. 167, n. 1, 27 agosto 1968, pp. 9-22, <a href="/wiki/Digital_object_identifier" title="Digital object identifier">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1016%2F0005-2744%2868%2990273-8">10.1016/0005-2744(68)90273-8</a>, <a href="/wiki/PMID" title="PMID">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/5686300">5686300</a>. <small>URL consultato il 1º febbraio 2023</small>.</cite></li> <li><cite class="citation pubblicazione" style="font-style:normal">(<span style="font-weight:bolder; font-size:80%"><abbr title="inglese">EN</abbr></span>) D. R. Phillips, J. A. Duley, D. J. Fennell e R. S. Holmes, <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/1268224"><span style="font-style:italic;">The self-association of L-alpha hydroxyacid oxidase</span></a>, in <span style="font-style:italic;">Biochimica Et Biophysica Acta</span>, vol. 427, n. 2, 14 aprile 1976, pp. 679-687, <a href="/wiki/Digital_object_identifier" title="Digital object identifier">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1016%2F0005-2795%2876%2990211-7">10.1016/0005-2795(76)90211-7</a>, <a href="/wiki/PMID" title="PMID">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/1268224">1268224</a>. <small>URL consultato il 1º febbraio 2023</small>.</cite></li> <li><cite class="citation pubblicazione" style="font-style:normal">(<span style="font-weight:bolder; font-size:80%"><abbr title="inglese">EN</abbr></span>) M. Schuman e V. Massey, <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/5569122"><span style="font-style:italic;">Purification and characterization of glycolic acid oxidase from pig liver</span></a>, in <span style="font-style:italic;">Biochimica Et Biophysica Acta</span>, vol. 227, n. 3, 10 marzo 1971, pp. 500-520, <a href="/wiki/Digital_object_identifier" title="Digital object identifier">DOI</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1016%2F0005-2744%2871%2990003-9">10.1016/0005-2744(71)90003-9</a>, <a href="/wiki/PMID" title="PMID">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/5569122">5569122</a>. <small>URL consultato il 1º febbraio 2023</small>.</cite></li></ul> <div class="noprint" style="width:100%; padding: 3px 0; display: flex; flex-wrap: wrap; row-gap: 4px; column-gap: 8px; box-sizing: border-box;"><div style="flex-basis: calc( 100% / 2 - 8px / 2 );"><style data-mw-deduplicate="TemplateStyles:r140555418">.mw-parser-output .itwiki-template-occhiello{width:100%;line-height:25px;border:1px solid #CCF;background-color:#F0EEFF;box-sizing:border-box}.mw-parser-output .itwiki-template-occhiello-progetto{background-color:#FAFAFA}@media screen{html.skin-theme-clientpref-night .mw-parser-output .itwiki-template-occhiello{background-color:#202122;border-color:#54595D}html.skin-theme-clientpref-night .mw-parser-output .itwiki-template-occhiello-progetto{background-color:#282929}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .itwiki-template-occhiello{background-color:#202122;border-color:#54595D}html.skin-theme-clientpref-os .mw-parser-output .itwiki-template-occhiello-progetto{background-color:#282929}}</style><div class="itwiki-template-occhiello"><span class="noviewer" typeof="mw:File"><a href="/wiki/File:DNA.png" class="mw-file-description" title="Biologia"><img alt=" " src="//upload.wikimedia.org/wikipedia/commons/thumb/4/47/DNA.png/24px-DNA.png" decoding="async" width="24" height="25" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/4/47/DNA.png/36px-DNA.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/4/47/DNA.png/47px-DNA.png 2x" data-file-width="298" data-file-height="314" /></a></span> <b><a href="/wiki/Portale:Biologia" title="Portale:Biologia">Portale Biologia</a></b></div></div><div style="flex-basis: calc( 100% / 2 - 8px / 2 );"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r140555418" /><div class="itwiki-template-occhiello"><span class="noviewer" typeof="mw:File"><a href="/wiki/File:Gnome-applications-science.svg" class="mw-file-description" title="Chimica"><img alt=" " src="//upload.wikimedia.org/wikipedia/commons/thumb/2/2e/Gnome-applications-science.svg/25px-Gnome-applications-science.svg.png" decoding="async" width="25" height="25" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/2/2e/Gnome-applications-science.svg/38px-Gnome-applications-science.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/2/2e/Gnome-applications-science.svg/50px-Gnome-applications-science.svg.png 2x" data-file-width="48" data-file-height="48" /></a></span> <b><a href="/wiki/Portale:Chimica" title="Portale:Chimica">Portale Chimica</a></b></div></div></div>    </div><noscript><img src="https://auth.wikimedia.org/loginwiki/wiki/Special:CentralAutoLogin/start?useformat=desktop&type=1x1&usesul3=1" alt="" width="1" height="1" style="border: none; position: absolute;"></noscript> <div class="printfooter" data-nosnippet="">Estratto da "<a dir="ltr" href="https://it.wikipedia.org/w/index.php?title=(S)-2-idrossiacido_ossidasi&oldid=143991952">https://it.wikipedia.org/w/index.php?title=(S)-2-idrossiacido_ossidasi&oldid=143991952</a>"</div></div> <div id="catlinks" class="catlinks" data-mw="interface"><div id="mw-normal-catlinks" class="mw-normal-catlinks"><a href="/wiki/Categoria:Categorie" title="Categoria:Categorie">Categoria</a>: <ul><li><a href="/wiki/Categoria:EC_1.1.3" title="Categoria:EC 1.1.3">EC 1.1.3</a></li></ul></div><div id="mw-hidden-catlinks" class="mw-hidden-catlinks mw-hidden-cats-hidden">Categorie nascoste: <ul><li><a href="/wiki/Categoria:Stub_-_enzimi" title="Categoria:Stub - enzimi">Stub - enzimi</a></li><li><a href="/wiki/Categoria:P591_letta_da_Wikidata" title="Categoria:P591 letta da Wikidata">P591 letta da Wikidata</a></li></ul></div></div> </div> </main> </div> <div class="mw-footer-container"> <footer id="footer" class="mw-footer" > <ul id="footer-info"> <li id="footer-info-lastmod"> Questa pagina è stata modificata per l'ultima volta il 13 mar 2025 alle 08:02.</li> <li id="footer-info-copyright">Il testo è disponibile secondo la <a rel="nofollow" class="external text" href="https://creativecommons.org/licenses/by-sa/4.0/deed.it">licenza Creative Commons Attribuzione-Condividi allo stesso modo</a>; possono applicarsi condizioni ulteriori. 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