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<!DOCTYPE html> <html lang="en"> <head> <meta charset="utf-8"/> <meta name="viewport" content="width=device-width,initial-scale=1"> <title>KEGG BRITE: Lipid Biosynthesis Proteins</title> <link rel="canonical" href="https://www.kegg.jp/brite/ko01004"> <script src="/js/jquery-3.5.1.min.js"></script> <script src="/js/jquery-ui.js"></script> <script src="/js/jquery.balloon.min.js"></script> <script src="/js/lz-string.min.js"></script> <script src="/kegg-bin/get_data.cgi?data=0021&id=show_brite.merged.js&v1.06"></script> <link rel="stylesheet" href="/css/kegg.css?v1.06"> <link rel="stylesheet" href="/css/get_htext.css?v1.06"> <link rel="stylesheet" href="/css/kegg-brite-viewer.css?v1.06" /> <link rel="stylesheet" href="/css/kegg-brite-control-panel.css?v1.06" /> <link rel="stylesheet" href="/css/jquery-ui.css" /> <style type="text/css"> html, body { -webkit-text-size-adjust: 100%; } body > .footer hr { margin-top: 0px; } body > .footer { margin-top: 5px; } h2 .subtitle:before { content: ' - '; 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display:none;"> <hr align="left" style="color:#dddddd; width:95%;"> <span class="current">0</span> / <span class="all">0</span> <button type="button" class="move prev"> <svg width="16px" height="10px"> <polyline points="2,8,8,2,14,8" stroke="#000" fill="none"> </svg> </button> <button type="button" class="move next"> <svg width="16px" height="10px"> <polyline points="2,2,8,8,14,2" stroke="#000" fill="none"> </svg> </button> </div> </form> </div> <h5> ID search <span class="ui-icon ui-icon-shuffle search-brite pruning "></span> <span class="ui-icon ui-icon-plus search-brite"></span> </h5> <div class="mapper search-brite"> <form class="query"> <div class="row" style="display:grid; grid-template-columns:115px 1fr; column-gap:5px;"> <div> <textarea class="query" rows="2" style="width:110px; resize:none;"></textarea> </div> <div> <input type="button" class="submit" value="Go"> <span class="ui-icon ui-icon-close clear-query hidden"></span> </div> </div> </form> <ul class="personal simple hidden"></ul> </div> <h5> Join <span class="ui-icon ui-icon-lightbulb join-brite id-highlight "></span> <span class="ui-icon ui-icon-shuffle join-brite pruning "></span> <span class="ui-icon ui-icon-plus join-brite"></span> </h5> <div class="mapper join-brite"> <ul class="binary-relation simple"> <li> <label> <input class="dataset" type="checkbox" value="ko2pathway" data-entry="0" data-header="1" data-inherit-entry="1" > <span class="title">Pathway</span> </label> </li> </ul> <ul class="personal simple"></ul> </div> <h5>Related Pathway</h5> <div class="related-data"> <ul class="simple"> <li><a href="/pathway/map01212" target="_blank">01212</a>  Fatty acid metabolism</li> <li><a href="/pathway/map00061" target="_blank">00061</a>  Fatty acid biosynthesis</li> <li><a href="/pathway/map00062" target="_blank">00062</a>  Fatty acid elongation</li> <li><a href="/pathway/map00074" target="_blank">00074</a>  Mycolic acid biosynthesis</li> <li><a href="/pathway/map00561" target="_blank">00561</a>  Glycerolipid metabolism</li> <li><a href="/pathway/map00564" target="_blank">00564</a>  Glycerophospholipid metabolism</li> <li><a href="/pathway/map01040" target="_blank">01040</a>  Biosynthesis of unsaturated fatty acids</li> </ul> </div> </div> <button class="close"> <img src="/Fig/left_triangle_12x12.png"> </button> <button class="open"> <img src="/Fig/right_triangle_12x12.png"> </button> </div> <div class="footer"> <hr>[ <a href="/kegg/compound/">COMPOUND</a> | <a href="/kegg/brite.html">BRITE</a> | <a href="/kegg/kegg2.html">KEGG2</a> | <a href="/kegg/">KEGG</a> ]<br>Last updated: December 11, 2024<br>Desaturase/elongase family classification based on <a href="http://www.ncbi.nlm.nih.gov/pubmed/17921532">Hashimoto et al. (2008)</a> </div> <div id="waiting-circle"> <img src="/Fig/waiting-circle-small.gif"> </div> <input type="text" class="hidden" id="displayControlPanel" value="" /> <input type="text" class="hidden" id="expandClass" value="" /> <input type="text" class="hidden" id="initialExpandedNodes" value="" /> <input type="text" class="hidden" id="expandedNodes" value="" /> <input type="text" class="hidden" id="initialParameters" value="htext=ko01004" /> <input type="text" class="hidden" id="pageParameters" /> <script type="text/javascript"> const env = {"org":"ko","joinPruningQuery":[],"isIndexFile":false,"devMode":false,"alignTerminalNode":false,"zoomout":null,"root":{"expanded":true,"isRoot":true,"children":[{"values":["<b>Fatty acid synthase</b>"],"children":[{"expanded":false,"children":[{"values":["<a href=\"/entry/K00665\">K00665</a> FASN; fatty acid synthase, animal type [EC:<a href=\"/entry/2.3.1.85\">2.3.1.85</a>]"],"children":[],"expanded":false}],"values":["Animal type"]},{"expanded":false,"children":[{"expanded":false,"children":[],"values":["<a href=\"/entry/K00668\">K00668</a> FAS1; fatty acid synthase subunit beta, fungi type [EC:<a href=\"/entry/2.3.1.86\">2.3.1.86</a>]"]},{"expanded":false,"values":["<a href=\"/entry/K00667\">K00667</a> FAS2; fatty acid synthase subunit alpha, fungi type [EC:<a href=\"/entry/2.3.1.86\">2.3.1.86</a>]"],"children":[]}],"values":["Yeast type"]},{"expanded":false,"children":[{"children":[],"values":["<a href=\"/entry/K11533\">K11533</a> fas; fatty acid synthase, bacteria type [EC:2.3.1.-]"],"expanded":false}],"values":["Bacteria type"]},{"children":[{"expanded":false,"children":[],"values":["<a href=\"/entry/K00645\">K00645</a> fabD, MCAT, MCT1; [acyl-carrier-protein] S-malonyltransferase [EC:<a href=\"/entry/2.3.1.39\">2.3.1.39</a>]"]},{"expanded":false,"values":["<a href=\"/entry/K00648\">K00648</a> fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:<a href=\"/entry/2.3.1.180\">2.3.1.180</a>]"],"children":[]},{"children":[],"values":["<a href=\"/entry/K18473\">K18473</a> fabY; acetoacetyl-[acyl-carrier protein] synthase [EC:<a href=\"/entry/2.3.1.180\">2.3.1.180</a>]"],"expanded":false},{"expanded":false,"values":["<a href=\"/entry/K00647\">K00647</a> fabB; 3-oxoacyl-[acyl-carrier-protein] synthase I [EC:<a href=\"/entry/2.3.1.41\">2.3.1.41</a>]"],"children":[]},{"children":[],"values":["<a href=\"/entry/K09458\">K09458</a> fabF, OXSM, CEM1; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:<a href=\"/entry/2.3.1.179\">2.3.1.179</a>]"],"expanded":false},{"expanded":false,"children":[],"values":["<a href=\"/entry/K00059\">K00059</a> fabG, OAR1; 3-oxoacyl-[acyl-carrier protein] reductase [EC:<a href=\"/entry/1.1.1.100\">1.1.1.100</a>]"]},{"children":[],"values":["<a href=\"/entry/K01716\">K01716</a> fabA; 3-hydroxyacyl-[acyl-carrier protein] dehydratase / trans-2-decenoyl-[acyl-carrier protein] isomerase [EC:<a href=\"/entry/4.2.1.59\">4.2.1.59</a> <a href=\"/entry/5.3.3.14\">5.3.3.14</a>]"],"expanded":false},{"expanded":false,"values":["<a href=\"/entry/K02372\">K02372</a> fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:<a href=\"/entry/4.2.1.59\">4.2.1.59</a>]"],"children":[]},{"children":[],"values":["<a href=\"/entry/K16363\">K16363</a> lpxC-fabZ; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase / 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:<a href=\"/entry/3.5.1.108\">3.5.1.108</a> <a href=\"/entry/4.2.1.59\">4.2.1.59</a>]"],"expanded":false},{"expanded":false,"values":["<a href=\"/entry/K00208\">K00208</a> fabI; enoyl-[acyl-carrier protein] reductase I [EC:<a href=\"/entry/1.3.1.9\">1.3.1.9</a> <a href=\"/entry/1.3.1.10\">1.3.1.10</a>]"],"children":[]},{"expanded":false,"children":[],"values":["<a href=\"/entry/K02371\">K02371</a> fabK; enoyl-[acyl-carrier protein] reductase II [EC:<a href=\"/entry/1.3.1.9\">1.3.1.9</a>]"]},{"expanded":false,"children":[],"values":["<a href=\"/entry/K10780\">K10780</a> fabL; enoyl-[acyl-carrier protein] reductase III [EC:<a href=\"/entry/1.3.1.104\">1.3.1.104</a>]"]},{"children":[],"values":["<a href=\"/entry/K00209\">K00209</a> fabV, ter; enoyl-[acyl-carrier protein] reductase / trans-2-enoyl-CoA reductase (NAD+) [EC:<a href=\"/entry/1.3.1.9\">1.3.1.9</a> <a href=\"/entry/1.3.1.44\">1.3.1.44</a>]"],"expanded":false},{"expanded":false,"values":["<a href=\"/entry/K18474\">K18474</a> fabM; trans-2-decenoyl-[acyl-carrier protein] isomerase [EC:<a href=\"/entry/5.3.3.14\">5.3.3.14</a>]"],"children":[]},{"expanded":false,"values":["<a href=\"/entry/K10251\">K10251</a> HSD17B12, KAR, IFA38; 17beta-estradiol 17-dehydrogenase / very-long-chain 3-oxoacyl-CoA reductase [EC:<a href=\"/entry/1.1.1.62\">1.1.1.62</a> <a href=\"/entry/1.1.1.330\">1.1.1.330</a>]"],"children":[]},{"expanded":false,"children":[],"values":["<a href=\"/entry/K10703\">K10703</a> HACD, PHS1, PAS2; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase [EC:<a href=\"/entry/4.2.1.134\">4.2.1.134</a>]"]},{"expanded":false,"children":[],"values":["<a href=\"/entry/K07753\">K07753</a> PECR; peroxisomal trans-2-enoyl-CoA reductase [EC:<a href=\"/entry/1.3.1.38\">1.3.1.38</a>]"]},{"values":["<a href=\"/entry/K10258\">K10258</a> TER, TSC13, CER10; very-long-chain enoyl-CoA reductase [EC:<a href=\"/entry/1.3.1.93\">1.3.1.93</a>]"],"children":[],"expanded":false},{"expanded":false,"children":[],"values":["<a href=\"/entry/K01071\">K01071</a> MCH; medium-chain acyl-[acyl-carrier-protein] hydrolase [EC:<a href=\"/entry/3.1.2.21\">3.1.2.21</a>]"]},{"children":[],"values":["<a href=\"/entry/K10782\">K10782</a> FATA; fatty acyl-ACP thioesterase A [EC:<a href=\"/entry/3.1.2.14\">3.1.2.14</a>]"],"expanded":false},{"expanded":false,"children":[],"values":["<a href=\"/entry/K10781\">K10781</a> FATB; fatty acyl-ACP thioesterase B [EC:<a href=\"/entry/3.1.2.14\">3.1.2.14</a> <a href=\"/entry/3.1.2.21\">3.1.2.21</a>]"]},{"values":["<a href=\"/entry/K01074\">K01074</a> PPT; palmitoyl-protein thioesterase [EC:<a href=\"/entry/3.1.2.22\">3.1.2.22</a>]"],"children":[],"expanded":false},{"values":["<a href=\"/entry/K01068\">K01068</a> ACOT1_2_4; acyl-coenzyme A thioesterase 1/2/4 [EC:<a href=\"/entry/3.1.2.2\">3.1.2.2</a>]"],"children":[],"expanded":false},{"values":["<a href=\"/entry/K11993\">K11993</a> ACOT6; acyl-CoA thioesterase 6 [EC:3.1.2.-]"],"children":[],"expanded":false},{"expanded":false,"values":["<a href=\"/entry/K17360\">K17360</a> ACOT7; acyl-coenzyme A thioesterase 7 [EC:<a href=\"/entry/3.1.2.2\">3.1.2.2</a>]"],"children":[]},{"expanded":false,"values":["<a href=\"/entry/K17361\">K17361</a> ACOT9; acyl-coenzyme A thioesterase 9 [EC:3.1.2.-]"],"children":[]},{"values":["<a href=\"/entry/K12417\">K12417</a> ACOT11; acyl-CoA thioesteraes 11 [EC:3.1.2.-]"],"children":[],"expanded":false},{"children":[],"values":["<a href=\"/entry/K17362\">K17362</a> ACOT13; acyl-coenzyme A thioesterase 13 [EC:3.1.2.-]"],"expanded":false},{"values":["<a href=\"/entry/K10804\">K10804</a> tesA; acyl-CoA thioesterase I [EC:3.1.2.- <a href=\"/entry/3.1.2.2\">3.1.2.2</a> <a href=\"/entry/3.1.1.2\">3.1.1.2</a> <a href=\"/entry/3.1.1.5\">3.1.1.5</a>]"],"children":[],"expanded":false},{"values":["<a href=\"/entry/K10805\">K10805</a> tesB; acyl-CoA thioesterase II [EC:3.1.2.-]"],"children":[],"expanded":false},{"expanded":false,"values":["<a href=\"/entry/K10806\">K10806</a> yciA; acyl-CoA thioesterase YciA [EC:3.1.2.-]"],"children":[]},{"expanded":false,"children":[],"values":["<a href=\"/entry/K12500\">K12500</a> tesC; thioesterase III [EC:3.1.2.-]"]},{"children":[],"values":["<a href=\"/entry/K11608\">K11608</a> mtfabH; mycobacterial beta-ketoacyl-[acyl-carrier protein] synthase III [EC:<a href=\"/entry/2.3.1.301\">2.3.1.301</a>]"],"expanded":false},{"values":["<a href=\"/entry/K11609\">K11609</a> kasA; meromycolic acid 3-oxoacyl-[acyl-carrier protein] synthase I [EC:<a href=\"/entry/2.3.1.293\">2.3.1.293</a>]"],"children":[],"expanded":false},{"expanded":false,"children":[],"values":["<a href=\"/entry/K27070\">K27070</a> kasB; meromycolic acid 3-oxoacyl-[acyl-carrier protein] synthase II [EC:<a href=\"/entry/2.3.1.294\">2.3.1.294</a>]"]},{"children":[],"values":["<a href=\"/entry/K11610\">K11610</a> mabA; meromycolic acid 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.-]"],"expanded":false},{"values":["<a href=\"/entry/K27071\">K27071</a> hadA; meromycolic acid (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase HadA [EC:4.2.1.-]"],"children":[],"expanded":false},{"expanded":false,"children":[],"values":["<a href=\"/entry/K27072\">K27072</a> hadB; meromycolic acid (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase HadB [EC:4.2.1.-]"]},{"values":["<a href=\"/entry/K27689\">K27689</a> hadAB; meromycolic acid (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase HadAB [EC:4.2.1.-]"],"children":[],"expanded":false},{"expanded":false,"values":["<a href=\"/entry/K27073\">K27073</a> hadC; meromycolic acid (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase HadC [EC:4.2.1.-]"],"children":[]},{"children":[],"values":["<a href=\"/entry/K27074\">K27074</a> hadD; meromycolic acid (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase HadD [EC:4.2.1.-]"],"expanded":false},{"expanded":false,"values":["<a href=\"/entry/K11611\">K11611</a> inhA; meromycolic acid enoyl-[acyl-carrier protein] reductase [EC:<a href=\"/entry/1.3.1.118\">1.3.1.118</a>]"],"children":[]},{"values":["<a href=\"/entry/K27985\">K27985</a> nasA; long-chain acyl-[acp]:L-phenylalanine N-acyltransferase [EC:<a href=\"/entry/2.3.1.327\">2.3.1.327</a>]"],"children":[],"expanded":false},{"expanded":false,"children":[],"values":["<a href=\"/entry/K27986\">K27986</a> nasB; branched-chain 2-oxoacid:malonyl-[acyl-carrier protein] acyltransferase [EC:<a href=\"/entry/2.3.1.328\">2.3.1.328</a>]"]}],"values":["Component type"],"expanded":false}],"expanded":false},{"values":[],"children":[],"expanded":false},{"children":[{"children":[{"expanded":false,"children":[],"values":["<a href=\"/entry/K00507\">K00507</a> SCD, desC; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:<a href=\"/entry/1.14.19.1\">1.14.19.1</a>]"]},{"children":[],"values":["<a href=\"/entry/K03921\">K03921</a> FAB2, SSI2, desA1; acyl-[acyl-carrier protein] desaturase [EC:<a href=\"/entry/1.14.19.2\">1.14.19.2</a> <a href=\"/entry/1.14.19.11\">1.14.19.11</a> <a href=\"/entry/1.14.19.26\">1.14.19.26</a>]"],"expanded":false},{"expanded":false,"values":["<a href=\"/entry/K03922\">K03922</a> desA2; acyl-[acyl-carrier protein] desaturase [EC:<a href=\"/entry/1.14.19.2\">1.14.19.2</a> 1.14.19.-]"],"children":[]},{"expanded":false,"values":["<a href=\"/entry/K22769\">K22769</a> desA3; NADPH-dependent stearoyl-CoA 9-desaturase [EC:1.14.19.-]"],"children":[]}],"values":["First"],"expanded":false},{"values":["Omega"],"children":[{"children":[],"values":["<a href=\"/entry/K10256\">K10256</a> FAD2; omega-6 fatty acid desaturase / acyl-lipid omega-6 desaturase (Delta-12 desaturase) [EC:<a href=\"/entry/1.14.19.6\">1.14.19.6</a> <a href=\"/entry/1.14.19.22\">1.14.19.22</a>]"],"expanded":false},{"expanded":false,"values":["<a href=\"/entry/K10255\">K10255</a> FAD6, desA; acyl-lipid omega-6 desaturase (Delta-12 desaturase) [EC:<a href=\"/entry/1.14.19.23\">1.14.19.23</a> <a href=\"/entry/1.14.19.45\">1.14.19.45</a>]"],"children":[]},{"expanded":false,"children":[],"values":["<a href=\"/entry/K10257\">K10257</a> FAD3, FAD7, FAD8, desB; acyl-lipid omega-3 desaturase [EC:<a href=\"/entry/1.14.19.25\">1.14.19.25</a> <a href=\"/entry/1.14.19.35\">1.14.19.35</a> <a href=\"/entry/1.14.19.36\">1.14.19.36</a>]"]},{"expanded":false,"values":["<a href=\"/entry/K10225\">K10225</a> FADS3; fatty acid desaturase 3 (Delta-13 desaturase) [EC:1.14.19.-]"],"children":[]}],"expanded":false},{"expanded":false,"children":[{"values":["<a href=\"/entry/K00508\">K00508</a> E1.14.19.3; linoleoyl-CoA desaturase [EC:<a href=\"/entry/1.14.19.3\">1.14.19.3</a>]"],"children":[],"expanded":false},{"children":[],"values":["<a href=\"/entry/K10224\">K10224</a> FADS1; acyl-CoA (8-3)-desaturase (Delta-5 desaturase) [EC:<a href=\"/entry/1.14.19.44\">1.14.19.44</a>]"],"expanded":false},{"expanded":false,"children":[],"values":["<a href=\"/entry/K10226\">K10226</a> FADS2; acyl-CoA 6-desaturase (Delta-6 desaturase) [EC:<a href=\"/entry/1.14.19.3\">1.14.19.3</a>]"]},{"values":["<a href=\"/entry/K12418\">K12418</a> DES4, des1; acyl-lipid (7-3)-desaturase (Delta-4 desaturase) [EC:<a href=\"/entry/1.14.19.31\">1.14.19.31</a>]"],"children":[],"expanded":false}],"values":["Front-end"]},{"expanded":false,"children":[{"expanded":false,"children":[],"values":["<a href=\"/entry/K04712\">K04712</a> DEGS; sphingolipid 4-desaturase/C4-monooxygenase [EC:<a href=\"/entry/1.14.19.17\">1.14.19.17</a> <a href=\"/entry/1.14.18.5\">1.14.18.5</a>]"]}],"values":["Sphingolipid"]},{"expanded":false,"children":[{"children":[],"values":["<a href=\"/entry/K12419\">K12419</a> FADS6; fatty acid desaturase 6 [EC:1.14.19.-]"],"expanded":false}],"values":["Other"]}],"values":["<b>Desaturase</b>"],"expanded":false},{"expanded":false,"values":[],"children":[]},{"expanded":false,"children":[{"expanded":false,"values":["LCFA"],"children":[{"children":[],"values":["<a href=\"/entry/K10245\">K10245</a> ELO2; fatty acid elongase 2 [EC:<a href=\"/entry/2.3.1.199\">2.3.1.199</a>]"],"expanded":false},{"expanded":false,"children":[],"values":["<a href=\"/entry/K10246\">K10246</a> ELO3; fatty acid elongase 3 [EC:<a href=\"/entry/2.3.1.199\">2.3.1.199</a>]"]}]},{"children":[{"values":["<a href=\"/entry/K10247\">K10247</a> ELOVL1; elongation of very long chain fatty acids protein 1 [EC:<a href=\"/entry/2.3.1.199\">2.3.1.199</a>]"],"children":[],"expanded":false},{"expanded":false,"children":[],"values":["<a href=\"/entry/K10205\">K10205</a> ELOVL2; elongation of very long chain fatty acids protein 2 [EC:<a href=\"/entry/2.3.1.199\">2.3.1.199</a>]"]},{"values":["<a href=\"/entry/K10249\">K10249</a> ELOVL4; elongation of very long chain fatty acids protein 4 [EC:<a href=\"/entry/2.3.1.199\">2.3.1.199</a>]"],"children":[],"expanded":false},{"children":[],"values":["<a href=\"/entry/K10244\">K10244</a> ELOVL5; elongation of very long chain fatty acids protein 5 [EC:<a href=\"/entry/2.3.1.199\">2.3.1.199</a>]"],"expanded":false},{"expanded":false,"children":[],"values":["<a href=\"/entry/K10203\">K10203</a> ELOVL6; elongation of very long chain fatty acids protein 6 [EC:<a href=\"/entry/2.3.1.199\">2.3.1.199</a>]"]},{"expanded":false,"children":[],"values":["<a href=\"/entry/K10250\">K10250</a> ELOVL7; elongation of very long chain fatty acids protein 7 [EC:<a href=\"/entry/2.3.1.199\">2.3.1.199</a>]"]}],"values":["PUFA"],"expanded":false},{"values":["Unclassified"],"children":[{"expanded":false,"values":["<a href=\"/entry/K10248\">K10248</a> ELOVL3; elongation of very long chain fatty acids protein 3 [EC:<a href=\"/entry/2.3.1.199\">2.3.1.199</a>]"],"children":[]}],"expanded":false}],"values":["<b>Elongase</b>"]},{"children":[],"values":[],"expanded":false},{"expanded":false,"children":[{"expanded":false,"values":["Modular PKS"],"children":[{"expanded":false,"children":[],"values":["<a href=\"/entry/K10817\">K10817</a> eryAI; 6-deoxyerythronolide-B synthase EryAI [EC:<a href=\"/entry/2.3.1.94\">2.3.1.94</a>]"]},{"expanded":false,"children":[],"values":["<a href=\"/entry/K04786\">K04786</a> irp1, HMWP1; yersiniabactin nonribosomal peptide/polyketide synthase"]},{"children":[],"values":["<a href=\"/entry/K04784\">K04784</a> irp2, HMWP2; yersiniabactin nonribosomal peptide synthetase"],"expanded":false},{"expanded":false,"values":["<a href=\"/entry/K11628\">K11628</a> mas; mycocerosic acid synthase [EC:<a href=\"/entry/2.3.1.111\">2.3.1.111</a>]"],"children":[]},{"values":["<a href=\"/entry/K12430\">K12430</a> pks1_15; 4-hydroxyphenylalkanoate synthase [EC:<a href=\"/entry/2.3.1.261\">2.3.1.261</a>]"],"children":[],"expanded":false},{"values":["<a href=\"/entry/K12431\">K12431</a> pks2; phthioceranic/hydroxyphthioceranic acid synthase [EC:<a href=\"/entry/2.3.1.287\">2.3.1.287</a>]"],"children":[],"expanded":false},{"expanded":false,"values":["<a href=\"/entry/K12436\">K12436</a> pks12; mycoketide-CoA synthase [EC:<a href=\"/entry/2.3.1.295\">2.3.1.295</a>]"],"children":[]},{"expanded":false,"values":["<a href=\"/entry/K12437\">K12437</a> pks13; polyketide synthase 13"],"children":[]},{"values":["<a href=\"/entry/K13611\">K13611</a> pksJ, baeJ; bacillaene biosynthesis, polyketide synthase / nonribosomal peptide synthetase PksJ/BaeJ"],"children":[],"expanded":false},{"expanded":false,"children":[],"values":["<a href=\"/entry/K13612\">K13612</a> pksL, baeL; bacillaene polyketide synthase PksL/BaeL"]},{"expanded":false,"values":["<a href=\"/entry/K13613\">K13613</a> pksM, baeM; bacillaene polyketide synthase PksM/BaeM"],"children":[]},{"values":["<a href=\"/entry/K13614\">K13614</a> pksN, baeN; bacillaene biosynthesis, polyketide synthase / nonribosomal peptide synthetase PksN/BaeN"],"children":[],"expanded":false},{"values":["<a href=\"/entry/K13615\">K13615</a> pksR, baeR; bacillaene polyketide synthase PksR/BaeR"],"children":[],"expanded":false},{"children":[],"values":["<a href=\"/entry/K12440\">K12440</a> ppsA; phthiocerol/phenolphthiocerol synthesis type-I polyketide synthase A [EC:<a href=\"/entry/2.3.1.292\">2.3.1.292</a>]"],"expanded":false},{"children":[],"values":["<a href=\"/entry/K12441\">K12441</a> ppsB; phthiocerol/phenolphthiocerol synthesis type-I polyketide synthase B [EC:<a href=\"/entry/2.3.1.292\">2.3.1.292</a>]"],"expanded":false},{"expanded":false,"values":["<a href=\"/entry/K12442\">K12442</a> ppsC; phthiocerol/phenolphthiocerol synthesis type-I polyketide synthase C [EC:<a href=\"/entry/2.3.1.292\">2.3.1.292</a>]"],"children":[]},{"children":[],"values":["<a href=\"/entry/K12443\">K12443</a> ppsD; phthiocerol/phenolphthiocerol synthesis type-I polyketide synthase D [EC:<a href=\"/entry/2.3.1.292\">2.3.1.292</a>]"],"expanded":false},{"expanded":false,"children":[],"values":["<a href=\"/entry/K12444\">K12444</a> ppsE; phthiocerol/phenolphthiocerol synthesis type-I polyketide synthase E [EC:<a href=\"/entry/2.3.1.292\">2.3.1.292</a>]"]}]},{"expanded":false,"values":["Component type"],"children":[{"children":[],"values":["<a href=\"/entry/K05551\">K05551</a> actI1, oxyA, tcmK, snoa1, aknB, mtmP; minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.- <a href=\"/entry/2.3.1.260\">2.3.1.260</a> <a href=\"/entry/2.3.1.235\">2.3.1.235</a>]"],"expanded":false},{"values":["<a href=\"/entry/K05552\">K05552</a> actI2, oxyB, tcmL, snoa2, aknC, mtmK; minimal PKS chain-length factor (CLF/KS beta) [EC:2.3.1.- <a href=\"/entry/2.3.1.260\">2.3.1.260</a> <a href=\"/entry/2.3.1.235\">2.3.1.235</a>]"],"children":[],"expanded":false},{"values":["<a href=\"/entry/K05553\">K05553</a> actI3, oxyC, tcmM, snoa3, aknD, mtmS; minimal PKS acyl carrier protein"],"children":[],"expanded":false},{"expanded":false,"children":[],"values":["<a href=\"/entry/K12420\">K12420</a> actIII, oxyJ, snoaD, aknA; ketoreductase [EC:1.1.1.-]"]},{"expanded":false,"values":["<a href=\"/entry/K05554\">K05554</a> actVII; aromatase [EC:4.2.1.-]"],"children":[]},{"expanded":false,"values":["<a href=\"/entry/K04790\">K04790</a> mbtC; mycobactin polyketide synthetase MbtC"],"children":[]},{"children":[],"values":["<a href=\"/entry/K04791\">K04791</a> mbtD; mycobactin polyketide synthetase MbtD"],"expanded":false}]}],"values":["<b>Polyketide synthase</b>"]},{"expanded":false,"values":[],"children":[]},{"children":[{"children":[{"expanded":false,"children":[],"values":["<a href=\"/entry/K01895\">K01895</a> ACSS1_2, acs; acetyl-CoA synthetase [EC:<a href=\"/entry/6.2.1.1\">6.2.1.1</a>]"]},{"children":[],"values":["<a href=\"/entry/K01908\">K01908</a> ACSS3, prpE; propionyl-CoA synthetase [EC:<a href=\"/entry/6.2.1.17\">6.2.1.17</a>]"],"expanded":false},{"values":["<a href=\"/entry/K01907\">K01907</a> AACS, acsA; acetoacetyl-CoA synthetase [EC:<a href=\"/entry/6.2.1.16\">6.2.1.16</a>]"],"children":[],"expanded":false},{"expanded":false,"values":["<a href=\"/entry/K23756\">K23756</a> ACSM1, LAE; medium-chain acyl-CoA ligase / lipoate-activating enzyme [EC:<a href=\"/entry/6.2.1.2\">6.2.1.2</a>]"],"children":[]},{"expanded":false,"values":["<a href=\"/entry/K01896\">K01896</a> ACSM; medium-chain acyl-CoA synthetase [EC:<a href=\"/entry/6.2.1.2\">6.2.1.2</a>]"],"children":[]},{"children":[],"values":["<a href=\"/entry/K23617\">K23617</a> ACSF2; medium-chain acyl-CoA ligase, mitochondrial [EC:<a href=\"/entry/6.2.1.2\">6.2.1.2</a>]"],"expanded":false},{"values":["<a href=\"/entry/K01913\">K01913</a> AAE7, ACN1; acetate/butyrate---CoA ligase [EC:<a href=\"/entry/6.2.1.1\">6.2.1.1</a> <a href=\"/entry/6.2.1.2\">6.2.1.2</a>]"],"children":[],"expanded":false},{"expanded":false,"children":[],"values":["<a href=\"/entry/K23618\">K23618</a> AAE11_12; acyl-activating enzyme 11/12 [EC:<a href=\"/entry/6.2.1.2\">6.2.1.2</a> 6.2.1.-]"]},{"expanded":false,"values":["<a href=\"/entry/K01905\">K01905</a> acdA; acetate---CoA ligase (ADP-forming) subunit alpha [EC:<a href=\"/entry/6.2.1.13\">6.2.1.13</a>]"],"children":[]},{"expanded":false,"children":[],"values":["<a href=\"/entry/K22224\">K22224</a> acdB; acetate---CoA ligase (ADP-forming) subunit beta [EC:<a href=\"/entry/6.2.1.13\">6.2.1.13</a>]"]},{"values":["<a href=\"/entry/K24012\">K24012</a> acdAB; acetate---CoA ligase (ADP-forming) [EC:<a href=\"/entry/6.2.1.13\">6.2.1.13</a>]"],"children":[],"expanded":false},{"children":[],"values":["<a href=\"/entry/K12507\">K12507</a> fadK; acyl-CoA synthetase [EC:6.2.1.-]"],"expanded":false},{"expanded":false,"children":[],"values":["<a href=\"/entry/K13776\">K13776</a> atuH; citronellyl-CoA synthetase [EC:6.2.1.-]"]}],"values":["Short/medium chain acyl-CoA ligase"],"expanded":false},{"expanded":false,"values":["Long/very long chain acyl-CoA ligase"],"children":[{"expanded":false,"children":[],"values":["<a href=\"/entry/K01897\">K01897</a> ACSL, fadD; long-chain-fatty-acid---CoA ligase [EC:<a href=\"/entry/6.2.1.3\">6.2.1.3</a>]"]},{"expanded":false,"children":[],"values":["<a href=\"/entry/K15013\">K15013</a> ACSBG; long-chain-fatty-acid---CoA ligase [EC:<a href=\"/entry/6.2.1.3\">6.2.1.3</a>]"]},{"expanded":false,"children":[],"values":["<a href=\"/entry/K03822\">K03822</a> K03822; putative long chain acyl-CoA synthase [EC:6.2.1.-]"]},{"children":[],"values":["<a href=\"/entry/K12429\">K12429</a> fadD36; fatty acid CoA ligase FadD36"],"expanded":false},{"values":["<a href=\"/entry/K08745\">K08745</a> SLC27A1_4, FATP1_4; solute carrier family 27 (fatty acid transporter), member 1/4 [EC:6.2.1.-]"],"children":[],"expanded":false},{"children":[],"values":["<a href=\"/entry/K08746\">K08746</a> SLC27A2, FACVL1, FATP2; solute carrier family 27 (fatty acid transporter), member 2 [EC:6.2.1.- <a href=\"/entry/6.2.1.3\">6.2.1.3</a>]"],"expanded":false},{"expanded":false,"values":["<a href=\"/entry/K08772\">K08772</a> SLC27A3, FATP3; solute carrier family 27 (fatty acid transporter), member 3 [EC:6.2.1.-]"],"children":[]}]},{"expanded":false,"children":[{"expanded":false,"children":[],"values":["<a href=\"/entry/K12421\">K12421</a> fadD9; fatty acid CoA ligase FadD9"]},{"children":[],"values":["<a href=\"/entry/K12423\">K12423</a> fadD21; fatty acid CoA ligase FadD21"],"expanded":false},{"expanded":false,"values":["<a href=\"/entry/K00142\">K00142</a> AASDH; acyl-CoA synthetase [EC:6.2.1.-]"],"children":[]},{"children":[],"values":["<a href=\"/entry/K00666\">K00666</a> K00666; fatty-acyl-CoA synthase [EC:6.2.1.-]"],"expanded":false}],"values":["Unknown"]}],"values":["<b>Acyl-CoA ligase</b>"],"expanded":false},{"values":[],"children":[],"expanded":false},{"children":[{"expanded":false,"children":[{"expanded":false,"children":[],"values":["<a href=\"/entry/K12422\">K12422</a> fadD10; medium/long-chain-fatty-acid---[acyl-carrier-protein] ligase FadD10 [EC:6.2.1.-]"]},{"expanded":false,"values":["<a href=\"/entry/K12425\">K12425</a> fadD23; long-chain fatty acid adenylase/transferase FadD23 [EC:<a href=\"/entry/6.2.1.57\">6.2.1.57</a>]"],"children":[]},{"values":["<a href=\"/entry/K12426\">K12426</a> fadD26; long-chain fatty acid adenylase/transferase FadD26 [EC:<a href=\"/entry/6.2.1.59\">6.2.1.59</a>]"],"children":[],"expanded":false},{"expanded":false,"children":[],"values":["<a href=\"/entry/K12427\">K12427</a> fadD28; long-chain fatty acid adenylyltransferase FadD28 [EC:<a href=\"/entry/6.2.1.49\">6.2.1.49</a>]"]},{"children":[],"values":["<a href=\"/entry/K21059\">K21059</a> fadD29; 4-hydroxyphenylalkanoate adenylyltransferase [EC:<a href=\"/entry/6.2.1.51\">6.2.1.51</a>]"],"expanded":false},{"expanded":false,"values":["<a href=\"/entry/K12428\">K12428</a> fadD32; fatty acyl-AMP ligase FadD32 [EC:6.2.1.-]"],"children":[]}],"values":["Fatty acyl-AMP ligase (FAAL)"]},{"expanded":false,"children":[{"children":[],"values":["<a href=\"/entry/K12424\">K12424</a> fadD22; 4-hydroxybenzoate adenylyltransferase [EC:<a href=\"/entry/6.2.1.50\">6.2.1.50</a>]"],"expanded":false}],"values":["Aryl-AMP ligase"]}],"values":["<b>Acyl-AMP ligase</b>"],"expanded":false},{"expanded":false,"children":[],"values":[]},{"values":["<b>Phospholipid acyltransferase</b>"],"children":[{"expanded":false,"values":["GPAT"],"children":[{"expanded":false,"values":["<a href=\"/entry/K00629\">K00629</a> GPAT1_2; glycerol-3-phosphate O-acyltransferase 1/2 [EC:<a href=\"/entry/2.3.1.15\">2.3.1.15</a>]"],"children":[]},{"values":["<a href=\"/entry/K13506\">K13506</a> GPAT3_4, AGPAT9, AGPAT6; glycerol-3-phosphate O-acyltransferase 3/4 [EC:<a href=\"/entry/2.3.1.15\">2.3.1.15</a>]"],"children":[],"expanded":false},{"expanded":false,"values":["<a href=\"/entry/K13507\">K13507</a> GAT; glycerol-3-phosphate O-acyltransferase / dihydroxyacetone phosphate acyltransferase [EC:<a href=\"/entry/2.3.1.15\">2.3.1.15</a> <a href=\"/entry/2.3.1.42\">2.3.1.42</a>]"],"children":[]},{"values":["<a href=\"/entry/K00630\">K00630</a> ATS1; glycerol-3-phosphate O-acyltransferase [EC:<a href=\"/entry/2.3.1.15\">2.3.1.15</a>]"],"children":[],"expanded":false},{"children":[],"values":["<a href=\"/entry/K13508\">K13508</a> GPAT; glycerol-3-phosphate acyltransferase [EC:<a href=\"/entry/2.3.1.15\">2.3.1.15</a> <a href=\"/entry/2.3.1.198\">2.3.1.198</a>]"],"expanded":false},{"values":["<a href=\"/entry/K00631\">K00631</a> plsB; glycerol-3-phosphate O-acyltransferase [EC:<a href=\"/entry/2.3.1.15\">2.3.1.15</a>]"],"children":[],"expanded":false},{"expanded":false,"values":["<a href=\"/entry/K03621\">K03621</a> plsX; phosphate acyltransferase [EC:<a href=\"/entry/2.3.1.274\">2.3.1.274</a>]"],"children":[]},{"expanded":false,"values":["<a href=\"/entry/K08591\">K08591</a> plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:<a href=\"/entry/2.3.1.275\">2.3.1.275</a>]"],"children":[]}]},{"children":[{"expanded":false,"children":[],"values":["<a href=\"/entry/K13509\">K13509</a> AGPAT1_2; lysophosphatidate acyltransferase [EC:<a href=\"/entry/2.3.1.51\">2.3.1.51</a>]"]},{"expanded":false,"values":["<a href=\"/entry/K13699\">K13699</a> ABHD5, CGI-58; abhydrolase domain-containing protein 5 [EC:<a href=\"/entry/2.3.1.51\">2.3.1.51</a>]"],"children":[]},{"children":[],"values":["<a href=\"/entry/K13513\">K13513</a> LCLAT1, AGPAT8; lysocardiolipin and lysophospholipid acyltransferase [EC:2.3.1.- <a href=\"/entry/2.3.1.51\">2.3.1.51</a>]"],"expanded":false},{"children":[],"values":["<a href=\"/entry/K13511\">K13511</a> TAZ; monolysocardiolipin acyltransferase [EC:2.3.1.-]"],"expanded":false},{"values":["<a href=\"/entry/K13517\">K13517</a> MBOAT1_2; lysophospholipid acyltransferase 1/2 [EC:<a href=\"/entry/2.3.1.51\">2.3.1.51</a> 2.3.1.-]"],"children":[],"expanded":false},{"expanded":false,"children":[],"values":["<a href=\"/entry/K13519\">K13519</a> LPT1, ALE1; lysophospholipid acyltransferase [EC:<a href=\"/entry/2.3.1.51\">2.3.1.51</a> <a href=\"/entry/2.3.1.23\">2.3.1.23</a> 2.3.1.-]"]},{"expanded":false,"values":["<a href=\"/entry/K13523\">K13523</a> AGPAT3_4; lysophosphatidic acid acyltransferase / lysophosphatidylinositol acyltransferase [EC:<a href=\"/entry/2.3.1.51\">2.3.1.51</a> 2.3.1.-]"],"children":[]},{"expanded":false,"values":["<a href=\"/entry/K00655\">K00655</a> plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:<a href=\"/entry/2.3.1.51\">2.3.1.51</a>]"],"children":[]},{"expanded":false,"children":[],"values":["<a href=\"/entry/K13510\">K13510</a> LPCAT1_2; lysophosphatidylcholine acyltransferase / lyso-PAF acetyltransferase [EC:<a href=\"/entry/2.3.1.23\">2.3.1.23</a> <a href=\"/entry/2.3.1.67\">2.3.1.67</a>]"]},{"values":["<a href=\"/entry/K13512\">K13512</a> LPCAT4, AGPAT7; lysophospholipid acyltransferase [EC:<a href=\"/entry/2.3.1.23\">2.3.1.23</a> 2.3.1.-]"],"children":[],"expanded":false},{"values":["<a href=\"/entry/K13514\">K13514</a> LPGAT1; lysophosphatidylglycerol acyltransferase 1 [EC:2.3.1.-]"],"children":[],"expanded":false},{"children":[],"values":["<a href=\"/entry/K13515\">K13515</a> LPCAT3, MBOAT5; lysophospholipid acyltransferase 5 [EC:<a href=\"/entry/2.3.1.23\">2.3.1.23</a> 2.3.1.-]"],"expanded":false},{"values":["<a href=\"/entry/K13516\">K13516</a> MBOAT7; lysophospholipid acyltransferase 7 [EC:2.3.1.-]"],"children":[],"expanded":false}],"values":["LPAAT/LPLAT"],"expanded":false}],"expanded":false},{"children":[],"values":[],"expanded":false},{"children":[{"children":[{"expanded":false,"children":[],"values":["<a href=\"/entry/K12432\">K12432</a> pks3_4; mycolipanoate synthase [EC:<a href=\"/entry/2.3.1.252\">2.3.1.252</a>]"]},{"values":["<a href=\"/entry/K12433\">K12433</a> pks5; polyketide synthase 5"],"children":[],"expanded":false},{"expanded":false,"values":["<a href=\"/entry/K12434\">K12434</a> pks7; polyketide synthase 7"],"children":[]},{"expanded":false,"values":["<a href=\"/entry/K12435\">K12435</a> pks8; polyketide synthase 8"],"children":[]},{"expanded":false,"children":[],"values":["<a href=\"/entry/K12439\">K12439</a> pks17; polyketide synthase 17"]}],"values":["Multifunctional type"],"expanded":false},{"values":["Component type"],"children":[{"children":[],"values":["<a href=\"/entry/K12445\">K12445</a> K12445; trans enoyl reductase [EC:1.3.1.-]"],"expanded":false}],"expanded":false}],"values":["<b>Others</b>"],"expanded":false}],"values":[]},"htextNo":"01004","columnWidth":[],"highlight":{},"visibleIndentHandle":false,"joinPruningColumn":[],"columnTitle":["Lipid biosynthesis protein"]} let isSmartPhone = navigator.userAgent.match(/iPhone|Android.+Mobile/) let isSmallView = (window.matchMedia && window.matchMedia('(max-width:640px)').matches) // パネルの開閉フラグが未定の場合はデバイスサイズ等をみて決める。 let e = document.getElementById('displayControlPanel') if (e != null) { if (e.value === '') { e.value = (isSmartPhone || isSmallView) ? 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