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Biocompatibility of NiTi Alloy Implants in vivo
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href="https://publications.waset.org/search?q=Gul%20Tosun">Gul Tosun</a>, <a href="https://publications.waset.org/search?q=Emine%20%C3%9Cnsaldi%20Latif%20%C3%96zler"> Emine Ünsaldi Latif Özler</a>, <a href="https://publications.waset.org/search?q=Nuri%20Orhan"> Nuri Orhan</a>, <a href="https://publications.waset.org/search?q=Ali%20Said%20Durmus"> Ali Said Durmus</a>, <a href="https://publications.waset.org/search?q=Hatice%20Er%C3%B6ks%C3%BCz"> Hatice Eröksüz</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In this study, the powders of Ni and Ti with 50.5 at.% Ni for 12 h were blended and cold pressed at the different pressures (50, 75 and100 MPa).The porous product obtained after Ni-Ti compacts were synthesized by SHS (self-propagating hightemperature synthesis) in the different preheating temperatures (200, 250 and 300oC) and heating rates (30, 60 and 90oC/min). The effects of the pressure, preheating temperature and heating rate were investigated on biocompatibility in vivo. The porosity in the synthesized products was in the range of 50.7–59.7 vol. %. The pressure, preheating temperature and heating rate were found to have an important effect on the biocompatibility in-vivo of the synthesized products. Max. fibrotic tissue within the porous implant was found in vivo periods (6 months), in which compacting pressure 100MPa. <iframe src="https://publications.waset.org/299.pdf" style="width:100%; height:400px;" frameborder="0"></iframe> <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/search?q=NiTi" title="NiTi">NiTi</a>, <a href="https://publications.waset.org/search?q=biomaterial" title=" biomaterial"> biomaterial</a>, <a href="https://publications.waset.org/search?q=SHS" title=" SHS"> SHS</a>, <a href="https://publications.waset.org/search?q=biocompatibility." title=" biocompatibility."> biocompatibility.</a> </p> <p class="card-text"><strong>Digital Object Identifier (DOI):</strong> <a href="https://doi.org/10.5281/zenodo.1328078" target="_blank">doi.org/10.5281/zenodo.1328078</a> </p> <a href="https://publications.waset.org/299/biocompatibility-of-niti-alloy-implants-in-vivo" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/299/apa" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">APA</a> <a href="https://publications.waset.org/299/bibtex" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">BibTeX</a> <a href="https://publications.waset.org/299/chicago" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">Chicago</a> <a href="https://publications.waset.org/299/endnote" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">EndNote</a> <a href="https://publications.waset.org/299/harvard" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">Harvard</a> <a href="https://publications.waset.org/299/json" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">JSON</a> <a href="https://publications.waset.org/299/mla" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">MLA</a> <a href="https://publications.waset.org/299/ris" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">RIS</a> <a href="https://publications.waset.org/299/xml" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">XML</a> <a href="https://publications.waset.org/299/iso690" target="_blank" rel="nofollow" class="btn btn-primary btn-sm">ISO 690</a> <a href="https://publications.waset.org/299.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">2830</span> </span> <p class="card-text"><strong>References:</strong></p> <br>[1] F. Sarsilmaz, N. Orhan, E. Unsaldi, A. S. Durmus, N.A. Colakoglu, A polyethylene-high proportion hydroxyapatite implant and its investigation in vivo Acta Bioeng Biomech, 9, 9-16, 2007. <br>[2] B.Y.Li, L. J. Rong, Y.Y. Li, V.E. Gjunter, Synthesis of porous Ni-Ti shape-memory alloys by self-propagating high temperature synthesis: reaction mechanism and an─▒sotropy ─▒n pore structure, Acta Mater, 48, 3895-904, 2000. <br>[3] A. Michiardi, C .Aparicio, J.A. Planell, F.J. Gil, Electrochemical behaviour of oxidized NiTi shape memory alloys for biomedical applications. Surf Coat Tech. 201,6484-8, 2007. <br>[4] C.L. Yeh, W.Y. Sung, Synthesis of NiTi intermetallics by selfpropagating combustion, J Alloy Compd, 376, 79-88, 2004. <br>[5] C.L. Chu, C.Y. Chung, P.H. Lin, S.D. Wang Fabrication of porous NiTi shape memory alloy for hard tissue implants by combustion synthesis, Mat Sci Eng A-Struct., 366,114-9, 2004. <br>[6] B.Y. Li, L.J. Rong, Y.Y. Li, Stres-strain behavior of porous Ni-Ti shape memory intermetallics synthesized from powder sintering, Intermetallics, 8, 643-6, 2000. <br>[7] D. Bogdanski, M. Koller, D. Muller, G. Muhr, M Bram, H.P. Buchkremer et al. Easy assessment of the biocompatibility of Ni-Ti alloys by in vitro cell culture experiments on a functionally graded Ni- NiTi-Ti material. Biomaterials, 23, 4549-4555, 2002. <br>[8] A. Kapanen, J. Ilvesaro, A. Danilov, J. Ryhanen, P. Lehenkari, J. Tuukkanen, Behaviour of Nitinol in osteoblast-like ROS-17 cell cultures. Biomaterials, 23, 645-650, 2002. <br>[9] P.K. Chu, Bioactivity of plasma implanted biomaterials Nucl Instrum Meth B, 24, 1-7, 2006. <br>[10] C.Y. Li, X.J. Yang, L.Y. Zhang, M. F. Chen, Z. D. Cui, In vivo histological evaluation of bioactive NiTi alloy after two years implantation, Mat Sci Eng C-Bio S, 27, 122-126, 2007. <br>[11] A. Bansiddhi, T.D. Sargeant, S.I. Stupp, D.C. Dunand, Porous NiTi for bone implants: A review, Acta Biomater, 4, 773-82, 2008. <br>[12] A. Biswas, Porous NiTi by thermal explosion mode of SHS: processing, mechanism and generation of single phase microstructure, Acta Mater, 53, 1415-1425, 2005. <br>[13] C. Shearwood, Y.Q. Fu, L. Yu, K.A. Khor, Spark plasma sintering of TiNi nano-powder , Scripta Mater, 52, 455-60, 2005. <br>[14] S. Rhalmi, M. Odin, M. Assad, M. Tabrizian, C.H. Rivard, L.H. Yahia, Hard. soft tissue and in vitro cell response to porous nickel- titanium: a biocompatibility evaluation Biomed Mater Eng, 9, 151-62, 1999. <br>[15] T. Duerig, A. Pelton, D. Stockel, An overview of nitinol medical applications Mat Sci Eng A-Struct, 273-275, 149-60, 1999. <br>[16] G. Tosun, L. Ozler, M. Kaya, N. Orhan, A study on microstructure and porosity of NiTi alloy implants produced by SHS, J Alloys Comp, 487, 605-611, 2009. <br>[17] D.A. Armitage, T.L. Parker, D.M. Grant, Biocompatibility and hemocompatibility of surface-modified NiTi alloys J Biomed Mater Res A, 66, 129-37, 2003. <br>[18] M.F. Chen, X.J. Yang, R.X. Hu, Z.D. Cui, H.C. Man, Bioactive NiTi shape memory alloy used as bone bonding implants, Mater. Sci. Eng. C, 24, 497, 2004. <br>[19] S.L. Zhu, X. J. Yang, M.F. Chen, C.Y. Li, Z.D. Cui, Effect of porous NiTi alloy on bone formation: A comparative investigation with bulk NiTi alloy for 15 weeks in vivo, Mat Sci Eng, 28, 1271-1275, 2008. </div> </div> </div> </main> <footer> <div id="infolinks" class="pt-3 pb-2"> <div class="container"> <div style="background-color:#f5f5f5;" class="p-3"> <div class="row"> <div class="col-md-2"> <ul class="list-unstyled"> About <li><a href="https://waset.org/page/support">About Us</a></li> <li><a href="https://waset.org/page/support#legal-information">Legal</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/WASET-16th-foundational-anniversary.pdf">WASET celebrates its 16th foundational anniversary</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Account <li><a href="https://waset.org/profile">My Account</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Explore <li><a href="https://waset.org/disciplines">Disciplines</a></li> <li><a href="https://waset.org/conferences">Conferences</a></li> <li><a href="https://waset.org/conference-programs">Conference Program</a></li> <li><a href="https://waset.org/committees">Committees</a></li> <li><a href="https://publications.waset.org">Publications</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Research <li><a href="https://publications.waset.org/abstracts">Abstracts</a></li> <li><a href="https://publications.waset.org">Periodicals</a></li> <li><a href="https://publications.waset.org/archive">Archive</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Open Science <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Science-Philosophy.pdf">Open Science Philosophy</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Science-Award.pdf">Open Science Award</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Society-Open-Science-and-Open-Innovation.pdf">Open Innovation</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Postdoctoral-Fellowship-Award.pdf">Postdoctoral Fellowship Award</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Scholarly-Research-Review.pdf">Scholarly Research Review</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Support <li><a href="https://waset.org/page/support">Support</a></li> <li><a href="https://waset.org/profile/messages/create">Contact Us</a></li> <li><a href="https://waset.org/profile/messages/create">Report Abuse</a></li> </ul> </div> </div> </div> </div> </div> <div class="container text-center"> <hr style="margin-top:0;margin-bottom:.3rem;"> <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank" class="text-muted small">Creative Commons Attribution 4.0 International License</a> <div id="copy" class="mt-2">© 2024 World Academy of Science, Engineering and Technology</div> </div> </footer> <a href="javascript:" id="return-to-top"><i class="fas fa-arrow-up"></i></a> <div class="modal" id="modal-template"> <div class="modal-dialog"> <div class="modal-content"> <div class="row m-0 mt-1"> <div class="col-md-12"> <button type="button" class="close" data-dismiss="modal" aria-label="Close"><span aria-hidden="true">×</span></button> </div> </div> <div class="modal-body"></div> </div> </div> </div> <script src="https://cdn.waset.org/static/plugins/jquery-3.3.1.min.js"></script> <script src="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/js/bootstrap.bundle.min.js"></script> <script src="https://cdn.waset.org/static/js/site.js?v=150220211556"></script> <script> jQuery(document).ready(function() { /*jQuery.get("https://publications.waset.org/xhr/user-menu", function (response) { jQuery('#mainNavMenu').append(response); });*/ jQuery.get({ url: "https://publications.waset.org/xhr/user-menu", cache: false }).then(function(response){ jQuery('#mainNavMenu').append(response); }); }); </script> </body> </html>