Kidney Disease - Renal Disorders

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The kidneys are essential for filtering waste products and excess fluids from the blood, regulating blood pressure, and maintaining electrolyte balance. Understanding kidney disease is vital due to its significant impact on a person's overall health and quality of life.</div><div><h3>What is Kidney Disease?</h3><a href="https://renaldisorders.com/about/index/kidney-disease" title="Kidney disease" target="_blank">Kidney disease</a> refers to a range of conditions that affect the proper functioning of the kidneys. It can be classified into two main types: acute kidney injury (AKI) and <a href="https://renaldisorders.com/about/index/chronic-kidney-disease-(ckd)" title="chronic kidney disease (CKD)" target="_blank">chronic kidney disease (CKD)</a>. AKI is characterized by a sudden loss of kidney function, often reversible with prompt treatment, while CKD is a progressive loss of kidney function over time.</div><div><h3>What Causes Kidney Disease?</h3>Numerous factors can lead to kidney disease, with the most common being <a href="https://renaldisorders.com/about/index/diabetes" title="diabetes" target="_blank">diabetes</a> and <a href="https://renaldisorders.com/about/index/hypertension" title="hypertension" target="_blank">hypertension</a>. These conditions damage the blood vessels in the kidneys, reducing their ability to filter blood effectively. Other causes include glomerulonephritis, polycystic kidney disease, prolonged obstruction of the urinary tract, and recurrent kidney infections.</div><div><h3>What Are the Symptoms of Kidney Disease?</h3>In the early stages, kidney disease may not present any noticeable symptoms. As the disease progresses, symptoms can include <a href="https://renaldisorders.com/about/index/fatigue" title="fatigue" target="_blank">fatigue</a>, reduced urine output, swelling in legs and ankles, shortness of breath, and persistent nausea. It's essential to monitor any changes in health and seek medical attention if these symptoms arise.</div><div><h3>How is Kidney Disease Diagnosed?</h3>Kidney disease is often diagnosed through blood tests, such as the serum creatinine test, which measures waste product levels in the blood, and the <a href="https://renaldisorders.com/about/index/glomerular-filtration-rate-(gfr)" title="glomerular filtration rate (GFR)" target="_blank">glomerular filtration rate (GFR)</a> test, which assesses kidney function. Urine tests can also detect abnormalities like proteinuria. Imaging studies, including ultrasound or CT scans, may be used to evaluate the kidneys' structure.</div><div><h3>What Are the Risk Factors for Kidney Disease?</h3>Several risk factors increase the likelihood of developing kidney disease. These include a family history of kidney disease, advanced age, obesity, smoking, and cardiovascular diseases. People with diabetes or hypertension are at particularly high risk and should have regular kidney function screenings.</div><div><h3>How Can Kidney Disease Be Managed?</h3>Managing kidney disease involves addressing underlying causes and adopting lifestyle changes to slow disease progression. This includes controlling <a href="https://renaldisorders.com/about/index/blood-pressure" title="blood pressure" target="_blank">blood pressure</a>, managing blood sugar levels, maintaining a balanced diet, and staying physically active. In advanced stages, treatments such as dialysis or a kidney transplant may be necessary.</div><div><h3>How Can Kidney Disease Be Prevented?</h3>Prevention strategies focus on maintaining a healthy lifestyle. Regular exercise, a balanced diet low in salt and sugar, adequate hydration, and avoiding tobacco and excessive alcohol consumption can significantly reduce the risk. Regular medical check-ups and monitoring of kidney function are crucial, especially for those with risk factors.</div><div><h3>What Is the Prognosis for People with Kidney Disease?</h3>The prognosis for kidney disease varies depending on the type and stage of the disease. Early detection and management can slow progression and improve quality of life. However, end-stage renal disease (ESRD) may require long-term treatments like <a href="https://renaldisorders.com/about/index/dialysis" title="dialysis" target="_blank">dialysis</a> or kidney transplantation. Lifelong monitoring and treatment adherence are critical for managing the condition effectively.</div><div><h3>What Are the Latest Advances in Kidney Disease Treatment?</h3>Recent advances in kidney disease treatment include the development of new medications that target specific pathways involved in disease progression, such as SGLT2 inhibitors for those with diabetes-related kidney disease. Research into regenerative medicine and bioartificial kidneys holds promise for future treatment options.</div><div>In conclusion, understanding kidney disease is crucial for preventing and managing renal disorders effectively. By recognizing the causes, symptoms, and risk factors, individuals can take proactive steps to maintain kidney health and improve their overall well-being.<br></div></div> </div> <div id="recent_papers"> <br><hr /><br><h2 class="heading1">Relevant Publications</h2> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38916150" target='_blank' title="Cost-effectiveness of add-on empagliflozin versus standard of care in management of CKD in Malaysia, Thailand and Vietnam - findings from a modelling study assessing an EMPA-KIDNEY eligible population, using CKD progression model.">Cost-effectiveness of add-on empagliflozin versus standard of care in management of CKD in Malaysia, Thailand and Vietnam - findings from a modelling study assessing an EMPA-KIDNEY eligible population, using CKD progression model.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38946053" target='_blank' title="Tubulocystic Carcinoma of Bile Ducts: A Distinct Type of Cholangiocarcinoma Associated With Adenofibroma-type Lesions.">Tubulocystic Carcinoma of Bile Ducts: A Distinct Type of Cholangiocarcinoma Associated With Adenofibroma-type Lesions.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38945640" target='_blank' title="Renal Complications in Portal Hypertension.">Renal Complications in Portal Hypertension.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38945692" target='_blank' title="A rare presentation of isolated candidal hepatic abscess in a maintenance hemodialysis patient.">A rare presentation of isolated candidal hepatic abscess in a maintenance hemodialysis patient.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38946781" target='_blank' title="Association between dietary protein intake and risk of chronic kidney disease: a systematic review and meta-analysis.">Association between dietary protein intake and risk of chronic kidney disease: a systematic review and meta-analysis.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38946975" target='_blank' title="Clonal hematopoiesis of indeterminate potential contributes to accelerated chronic kidney disease progression.">Clonal hematopoiesis of indeterminate potential contributes to accelerated chronic kidney disease progression.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38947587" target='_blank' title="Chronic Kidney Disease Study in Diabetic Patients: Insights From Primary Care Units in Northern Portugal.">Chronic Kidney Disease Study in Diabetic Patients: Insights From Primary Care Units in Northern Portugal.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38942091" target='_blank' title="Activation of TAS2R4 signaling attenuates podocyte injury induced by high glucose.">Activation of TAS2R4 signaling attenuates podocyte injury induced by high glucose.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38943304" target='_blank' title="Comfort Level of Patients Undergoing Hemodialysis and Associated Factors in Turkey: A Cross-Sectional Study.">Comfort Level of Patients Undergoing Hemodialysis and Associated Factors in Turkey: A Cross-Sectional Study.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38944202" target='_blank' title="Sodium Tungstate (NaW) Decreases Inflammation and Renal Fibrosis in Diabetic Nephropathy.">Sodium Tungstate (NaW) Decreases Inflammation and Renal Fibrosis in Diabetic Nephropathy.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38945255" target='_blank' title="IGF2BP3/NCBP1 complex inhibits renal tubular senescence through regulation of CDK6 mRNA stability.">IGF2BP3/NCBP1 complex inhibits renal tubular senescence through regulation of CDK6 mRNA stability.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38946127" target='_blank' title="Management of Massive Flank Hernia After Lateral Lumbar Fusion: Preoperative Botulinum Toxin Injections and Open Repair - A Case Report.">Management of Massive Flank Hernia After Lateral Lumbar Fusion: Preoperative Botulinum Toxin Injections and Open Repair - A Case Report.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38947355" target='_blank' title="Association between machine learning-assisted heavy metal exposures and diabetic kidney disease: a cross-sectional survey and Mendelian randomization analysis.">Association between machine learning-assisted heavy metal exposures and diabetic kidney disease: a cross-sectional survey and Mendelian randomization analysis.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38947546" target='_blank' title="Relapsing nephrotic syndrome with acute renal failure following a unique episode of multiple bee stings: A case report.">Relapsing nephrotic syndrome with acute renal failure following a unique episode of multiple bee stings: A case report.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38953354" target='_blank' title="Brincidofovir inhibits polyomavirus infection .">Brincidofovir inhibits polyomavirus infection .</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38953545" target='_blank' title="Combining telemedicine and in-person visits to deliver care to patients with severe chronic kidney disease (CKD): Lessons learned from COVID-19.">Combining telemedicine and in-person visits to deliver care to patients with severe chronic kidney disease (CKD): Lessons learned from COVID-19.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38953510" target='_blank' title="Recent developments in the management of resistant hypertension: focus on endothelin receptor antagonists.">Recent developments in the management of resistant hypertension: focus on endothelin receptor antagonists.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38953786" target='_blank' title="Wearable device-measured moderate to vigorous physical activity and risk of degenerative aortic valve stenosis.">Wearable device-measured moderate to vigorous physical activity and risk of degenerative aortic valve stenosis.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38954486" target='_blank' title="Inflammation primes the murine kidney for recovery by activating AZIN1 adenosine-to-inosine editing.">Inflammation primes the murine kidney for recovery by activating AZIN1 adenosine-to-inosine editing.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38954308" target='_blank' 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src="https://cancerscience.net/media-partners/cancerscience.png" alt="Cancer Science" title="Cancer Science"></a></li> <li class="slide"><a href="https://vaccine-studies.com" title="Vaccine Studies" target="_blank"><img src="https://vaccine-studies.com/media-partners/vaccine-studies.png" alt="Vaccine Studies" title="Vaccine Studies"></a></li> <li class="slide"><a href="https://gynecology.blog" title="Gynecology" target="_blank"><img src="https://gynecology.blog/media-partners/gynecology.png" alt="Gynecology" title="Gynecology"></a></li> <li class="slide"><a href="https://food-nutrition.blog" title="Food Nutrition" target="_blank"><img src="https://food-nutrition.blog/media-partners/food-nutrition.png" alt="Food Nutrition" title="Food Nutrition"></a></li> <li class="slide"><a href="https://nursing-science.com" title="Nursing Science" target="_blank"><img src="https://nursing-science.com/media-partners/nursing-science.png" alt="Nursing Science" title="Nursing Science"></a></li> <li 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title="Catalysis"></a></li> <li class="slide"><a href="https://neonatalbiology.com" title="Neonatal Biology" target="_blank"><img src="https://neonatalbiology.com/media-partners/neonatalbiology.png" alt="Neonatal Biology" title="Neonatal Biology"></a></li> <li class="slide"><a href="https://neonataldisorders.com" title="Neonatal Disorders" target="_blank"><img src="https://neonataldisorders.com/media-partners/neonataldisorders.png" alt="Neonatal Disorders" title="Neonatal Disorders"></a></li> <li class="slide"><a href="https://mutation.blog" title="Mutation" target="_blank"><img src="https://mutation.blog/media-partners/mutation.png" alt="Mutation" title="Mutation"></a></li> <li class="slide"><a href="https://nanotechnology.blog" title="Nanotechnology" target="_blank"><img src="https://nanotechnology.blog/media-partners/nanotechnology.png" alt="Nanotechnology" title="Nanotechnology"></a></li> <li class="slide"><a href="https://toxicology.blog" title="Toxicology" target="_blank"><img src="https://toxicology.blog/media-partners/toxicology.png" alt="Toxicology" title="Toxicology"></a></li> <li class="slide"><a href="https://darkbiotechnology.com" title="Dark Biotechnology" target="_blank"><img src="https://darkbiotechnology.com/media-partners/darkbiotechnology.png" alt="Dark Biotechnology" title="Dark Biotechnology"></a></li> <li class="slide"><a href="https://pollutiontoxicology.com" title="Pollution Toxicology" target="_blank"><img src="https://pollutiontoxicology.com/media-partners/pollutiontoxicology.png" alt="Pollution Toxicology" title="Pollution Toxicology"></a></li> <li class="slide"><a href="https://cellbiology.blog" title="Cell Biology" target="_blank"><img src="https://cellbiology.blog/media-partners/cellbiology.png" alt="Cell Biology" title="Cell Biology"></a></li> <li class="slide"><a href="https://bioanalyticalresearch.com" title="Bioanalytical Research" target="_blank"><img 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alt="Epidemiology" title="Epidemiology"></a></li> <li class="slide"><a href="https://histology.blog" title="Histology" target="_blank"><img src="https://histology.blog/media-partners/histology.png" alt="Histology" title="Histology"></a></li> </ul> </div> </div> <div class="citybg"> <div class="container"> <h2>Relevant Topics</h2> <ul class="cities"> <li> <a href="https://renaldisorders.com/archive/tag/ace-inhibitors/" title="ACE inhibitors"> ACE inhibitors </a></li> <li> <a href="https://renaldisorders.com/archive/tag/acute-kidney-injury/" title="acute kidney injury"> acute kidney injury </a></li> <li> <a href="https://renaldisorders.com/archive/tag/albumin-therapy/" title="Albumin Therapy"> Albumin Therapy </a></li> <li> <a href="https://renaldisorders.com/archive/tag/angiotensin-converting-enzyme/" title="angiotensin-converting enzyme"> angiotensin-converting enzyme </a></li> <li> <a href="https://renaldisorders.com/archive/tag/benazepril/" title="benazepril"> benazepril </a></li> 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