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tabindex="-1"></div><div class="section"><div class="block block--content" id="block-mainpagecontent-2"><article><h1>National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)</h1><p><strong>Scientific Director: <a href="/pi/john-oshea">John O’Shea, M.D.</a></strong></p> <p>NIAMS focuses on studying diseases that involve bones, joints, muscles and skin, which affect almost every person in America and are a major cause of disability in the US and elsewhere. The Intramural Research Program (IRP) provides a unique contribution to the overall NIAMS research agenda and utilizes a broad spectrum of disciplines to conduct clinical and laboratory research related to arthritis and musculoskeletal and skin diseases.</p> <p>For 25 years, the IRP has established a tradition of excellence with a strong focus on long-term, high-risk research aiming to develop innovative therapies for a number of serious disorders, for which satisfactory treatments are non-existent.</p> <p>The program is firmly grounded on a foundation of world-class basic science research and technology within the NIAMS IRP itself, as well as with widespread collaborations with other outstanding intramural and extramural clinicians and scientists. The result is a cocktail of cutting-edge research in immunology, inflammation, signal transduction, epigenetics and transcriptional regulation, genetics, stem cell biology, structural biology, developmental biology, biophysics, and cartilage biology, with a generous twist of translational investigation in a number of clinical specialties.</p> <p><a href="https://www.niams.nih.gov/Research/Ongoing_Research/default.asp">Learn more about the National Institute of Arthritis and Musculoskeletal and Skin Diseases’ Intramural Research Program.</a></p><div class="updated"> <p class="updated__date"><small>This page was last updated on Tuesday, January 11, 2022</small></p> </div></article> </div></div></main><footer class="footer"><div class="footer-content"><div class="section"><div class="footer-content__wrapper"><div class="footer-content__item"><h2 class="footer-content__heading">Get IRP Updates</h2></div><div class="footer-content__item"><p class="footer-content__text"><a 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