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syndrome (DSS)</title> <meta name="description" content="Search results for: dengue shock syndrome (DSS)"> <meta name="keywords" content="dengue shock syndrome (DSS)"> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1, maximum-scale=1, user-scalable=no"> <meta charset="utf-8"> <link href="https://cdn.waset.org/favicon.ico" type="image/x-icon" rel="shortcut icon"> <link href="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/css/bootstrap.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/plugins/fontawesome/css/all.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/css/site.css?v=150220211555" rel="stylesheet"> </head> <body> <header> <div class="container"> <nav class="navbar navbar-expand-lg navbar-light"> <a class="navbar-brand" href="https://waset.org"> <img src="https://cdn.waset.org/static/images/wasetc.png" alt="Open Science Research Excellence" title="Open Science Research Excellence" /> </a> <button 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action="https://publications.waset.org/abstracts/search"> <div id="custom-search-input"> <div class="input-group"> <i class="fas fa-search"></i> <input type="text" class="search-query" name="q" placeholder="Author, Title, Abstract, Keywords" value="dengue shock syndrome (DSS)"> <input type="submit" class="btn_search" value="Search"> </div> </div> </form> </div> </div> <div class="row mt-3"> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Commenced</strong> in January 2007</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Frequency:</strong> Monthly</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Edition:</strong> International</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Paper Count:</strong> 1253</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: dengue shock syndrome (DSS)</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">983</span> Interaction Effects of Vitamin D Supplementation and Aerobic Exercises on Balance and Physical Performance in Children with Down Syndrome</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mohamed%20A.%20Eid">Mohamed A. Eid</a>, <a href="https://publications.waset.org/abstracts/search?q=Sobhy%20M.%20Aly"> Sobhy M. Aly</a>, <a href="https://publications.waset.org/abstracts/search?q=Marwa%20M.%20Ibrahim"> Marwa M. Ibrahim</a>, <a href="https://publications.waset.org/abstracts/search?q=Nadia%20L.%20%20Radwan"> Nadia L. Radwan</a> </p> <p class="card-text"><strong>Abstract:</strong></p> To investigate the interaction effects of vitamin D supplementation combined with aerobic exercises (AE) and conventional physical therapy program (CPTP) on balance and physical performance in children with Down syndrome (DS).Methods: A randomized controlled trial was conducted for 38 children with DS, with ages ranging from 8 to 12 years. They were divided randomly to two groups. The control group (n=19) received the CPTP, while the study group (n=19) received the CPTP, AE, and vitamin D in the form of an oral daily dose of vitamin D3 400 IU (Cholecalciferol). Evaluation of balance by using the Biodex Stability System and physical performance by using the six-minute walk test (6MWT)was performed before and after 12 weeks of the treatment program. Findings: All groups showed a significant improvement in balance and physical performance after treatment (p < 0.05). The study group showed a significant improvement in balance and physical performancecompared with that of the control group (p < 0.05). Conclusion: Vitamin D supplementation combined with AE and CPTP could improve balance and physical performance in children with DS. Therefore, vitamin D and AEshould be considered as adjunctive to the rehabilitation program of these children. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=aerobic%20exercises" title="aerobic exercises">aerobic exercises</a>, <a href="https://publications.waset.org/abstracts/search?q=balance" title=" balance"> balance</a>, <a href="https://publications.waset.org/abstracts/search?q=down%20syndrome" title=" down syndrome"> down syndrome</a>, <a href="https://publications.waset.org/abstracts/search?q=physical%20performance" title=" physical performance"> physical performance</a>, <a href="https://publications.waset.org/abstracts/search?q=vitamin%20D" title=" vitamin D"> vitamin D</a> </p> <a href="https://publications.waset.org/abstracts/138154/interaction-effects-of-vitamin-d-supplementation-and-aerobic-exercises-on-balance-and-physical-performance-in-children-with-down-syndrome" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/138154.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">232</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">982</span> Imprecise Vowel Articulation in Down Syndrome: An Acoustic Study</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Anitha%20Naittee%20Abraham">Anitha Naittee Abraham</a>, <a href="https://publications.waset.org/abstracts/search?q=N.%20Sreedevi"> N. Sreedevi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Individuals with Down syndrome (DS) have relatively better expressive language compared to other individuals with intellectual disabilities. Reduced speech intelligibility is one of the major concerns of this group of individuals due to their anatomical and physiological differences. The study investigated the vowel articulation of Malayalam speaking children with DS in the age range of 5-10 years. The vowel production of 10 children with DS was compared with typically developing children in the same age range. Vowels were extracted from 3 words with the corner vowels /a/, /i/ and /u/ in the word-initial position, using Praat (version 5.3.23) software. Acoustic analysis was based on vowel space area (VSA), Formant centralization ration (FCR) and F2i/F2u. The findings revealed increased formant values for the control group except for F2a and F2u. Also, the experimental group had higher FCR, lower VSA, and F2i/F2u values suggestive of imprecise vowel articulation due to restricted tongue movements. The results of the independent t-test revealed a significant difference in F1a, F2i, F2u, VSA, FCR and F2i/F2u values between the experimental and control group. These findings support the fact that children with DS have imprecise vowel articulation that interferes with the overall speech intelligibility. Hence it is essential to target the oromotor skills to enhance the speech intelligibility which in turn benefit in the social and vocational domains of these individuals. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Down%20syndrome" title="Down syndrome">Down syndrome</a>, <a href="https://publications.waset.org/abstracts/search?q=FCR" title=" FCR"> FCR</a>, <a href="https://publications.waset.org/abstracts/search?q=vowel%20articulation" title=" vowel articulation"> vowel articulation</a>, <a href="https://publications.waset.org/abstracts/search?q=vowel%20space" title=" vowel space"> vowel space</a> </p> <a href="https://publications.waset.org/abstracts/99225/imprecise-vowel-articulation-in-down-syndrome-an-acoustic-study" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/99225.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">185</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">981</span> Isolation and Characterization White Spot Syndrome Protein Envelope Protein 19 from Black Tiger Shrimp (Penaeus monodon)</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Andi%20Aliah%20Hidayani">Andi Aliah Hidayani</a>, <a href="https://publications.waset.org/abstracts/search?q=Asmi%20Citra%20Malina%20A.%20R.%20Tassakka"> Asmi Citra Malina A. R. Tassakka</a>, <a href="https://publications.waset.org/abstracts/search?q=Andi%20Parenrengi"> Andi Parenrengi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Vanname Shrimp is one of the high yielding varieties that are more resistant to virus attacks. However, now this shrimp more death due to virus attack such as white spot disease caused by white spot syndrome virus (WSSV). Various efforts have done to prevent the disease, like immunostimulatory, probiotics, and vaccine. White spot syndrome virus (WSSV) envelope protein VP19 gene is important because of its involvement in the system infection of shrimp. This study aimed to isolate and characterize an envelope protein VP19 – encoding gene of WSSV using WSSV infected Vanname Shrimp sample from some areas in South Sulawesi (Pangkep, Barru and Pinrang). The genomic of DNA were isolated from shrimp muscle using DTAB-CTAB method. Isolation of gene encoding envelope protein VP19 WSSV ws successfully performed with the results of the length of DNA fragment was 387 bp. The results of homology analysis using BLASTn homology suggested that these isolates genes from Barru, Pangkep and Pinrang have closest relationship with isolates from Mexican. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=vanname" title="vanname">vanname</a>, <a href="https://publications.waset.org/abstracts/search?q=shrimp" title=" shrimp"> shrimp</a>, <a href="https://publications.waset.org/abstracts/search?q=WSSV" title=" WSSV"> WSSV</a>, <a href="https://publications.waset.org/abstracts/search?q=viral%20protein%2019" title=" viral protein 19"> viral protein 19</a> </p> <a href="https://publications.waset.org/abstracts/20491/isolation-and-characterization-white-spot-syndrome-protein-envelope-protein-19-from-black-tiger-shrimp-penaeus-monodon" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/20491.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">535</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">980</span> Association of Genetic Variants of Apolipoprotein A5 Gene with the Metabolic Syndrome in the Pakistani Population</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Muhammad%20Fiaz">Muhammad Fiaz</a>, <a href="https://publications.waset.org/abstracts/search?q=Muhammad%20Saqlain"> Muhammad Saqlain</a>, <a href="https://publications.waset.org/abstracts/search?q=Bernard%20M.%20Y.%20Cheung"> Bernard M. Y. Cheung</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20M.%20Saqlan%20Naqvi"> S. M. Saqlan Naqvi</a>, <a href="https://publications.waset.org/abstracts/search?q=Ghazala%20Kaukab%20Raja"> Ghazala Kaukab Raja</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Association of C allele of rs662799 SNP of APOA5 gene with metabolic syndrome (MetS) has been reported in different populations around the world. A case control study was conducted to explore the relationship of rs662799 variants (T/C) with the MetS and the associated risk phenotypes in a population of Pakistani origin. Methods: MetS was deﬁned according to the IDF criteria. Blood samples were collected from the Pakistan Institute of Medical Sciences, Islamabad, Pakistan for biochemical profiling and DNA extraction. Genotyping of rs662799 was performed using mass ARRAY, iPEX Gold technology. A total of 712 unrelated case and control subjects were genotyped. Data were analyzed using Plink software and SPSS 16.0. Results: The risk allele C of rs662799 showed highly significant association with MetS (OR=1.5, Ρ=0.002). Among risk phenotypes, dyslipidemia, and obesity showed strong association with SNP (OR=1.49, p=0.03; OR =1.46, p=0.01) respectively in models adjusted for age and gender. Conclusion: The rs662799C allele is a significant risk marker for MetS in the local Pakistani population studied. The effect of the SNP is more on dyslipidemia than the other components of the MetS. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=metabolic%20syndrome" title="metabolic syndrome">metabolic syndrome</a>, <a href="https://publications.waset.org/abstracts/search?q=APOA5" title=" APOA5"> APOA5</a>, <a href="https://publications.waset.org/abstracts/search?q=rs662799" title=" rs662799"> rs662799</a>, <a href="https://publications.waset.org/abstracts/search?q=dyslipidemia" title=" dyslipidemia"> dyslipidemia</a>, <a href="https://publications.waset.org/abstracts/search?q=obesity" title=" obesity"> obesity</a> </p> <a href="https://publications.waset.org/abstracts/16134/association-of-genetic-variants-of-apolipoprotein-a5-gene-with-the-metabolic-syndrome-in-the-pakistani-population" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/16134.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">503</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">979</span> Molecular Characterization of White Spot Syndrome Virus in Some Cultured Penaeid Shrimps of Coastal Regions in Bangladesh</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Md.%20Baki%20Billah">Md. Baki Billah</a>, <a href="https://publications.waset.org/abstracts/search?q=Suraiya%20Parveen"> Suraiya Parveen</a>, <a href="https://publications.waset.org/abstracts/search?q=Shuvra%20Kanti%20Dey"> Shuvra Kanti Dey</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Bangladesh is earning a lot of foreign currency by exporting shrimp, but this industry is facing a tremendous problem due to the infection of white spot syndrome virus (WSSV). This study was undermined to develop rapid detection method of WSSV. A total of shrimp samples 240 collected from the 12 shrimp farms of different coastal regions (Satkhira, Khulna, and Bagerhat) were analyzed by conventional PCR using VP28 and VP664 gene-specific primers. In satkhira, Bagerhat and Khulna 39, 41 and 29 samples were found WSSV positive respectively. Real-time PCR using 71-bp amplicon for VP664 gene correlated well with conventional PCR data. The prevalence rates of WSSV among the collected 240 samples were Satkhira 38%, Khulna 47% and Bagerhat 50%. Molecular analysis of the VP28 gene sequences of WSSV revealed that Bangladeshi strains phylogenetically affiliated to the strains belong to India. This work concluded that WSSV infections are widely distributed in the coastal regions cultured shrimp in Bangladesh. Physico-chemical parameters were within the range of fish culture. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=coastal%20regions%20of%20Bangladesh" title="coastal regions of Bangladesh">coastal regions of Bangladesh</a>, <a href="https://publications.waset.org/abstracts/search?q=PCR" title=" PCR"> PCR</a>, <a href="https://publications.waset.org/abstracts/search?q=shrimp" title=" shrimp"> shrimp</a>, <a href="https://publications.waset.org/abstracts/search?q=white%20spot%20syndrome%20virus" title=" white spot syndrome virus"> white spot syndrome virus</a> </p> <a href="https://publications.waset.org/abstracts/95250/molecular-characterization-of-white-spot-syndrome-virus-in-some-cultured-penaeid-shrimps-of-coastal-regions-in-bangladesh" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/95250.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">128</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">978</span> An Experimental Investigation on Explosive Phase Change of Liquefied Propane During a Bleve Event</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Frederic%20Heymes">Frederic Heymes</a>, <a href="https://publications.waset.org/abstracts/search?q=Michael%20Albrecht%20Birk"> Michael Albrecht Birk</a>, <a href="https://publications.waset.org/abstracts/search?q=Roland%20Eyssette"> Roland Eyssette</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Boiling Liquid Expanding Vapor Explosion (BLEVE) has been a well know industrial accident for over 6 decades now, and yet it is still poorly predicted and avoided. BLEVE is created when a vessel containing a pressure liquefied gas (PLG) is engulfed in a fire until the tank rupture. At this time, the pressure drops suddenly, leading the liquid to be in a superheated state. The vapor expansion and the violent boiling of the liquid produce several shock waves. This works aimed at understanding the contribution of vapor ad liquid phases in the overpressure generation in the near field. An experimental work was undertaken at a small scale to reproduce realistic BLEVE explosions. Key parameters were controlled through the experiments, such as failure pressure, fluid mass in the vessel, and weakened length of the vessel. Thirty-four propane BLEVEs were then performed to collect data on scenarios similar to common industrial cases. The aerial overpressure was recorded all around the vessel, and also the internal pressure changed during the explosion and ground loading under the vessel. Several high-speed cameras were used to see the vessel explosion and the blast creation by shadowgraph. Results highlight how the pressure field is anisotropic around the cylindrical vessel and highlights a strong dependency between vapor content and maximum overpressure from the lead shock. The time chronology of events reveals that the vapor phase is the main contributor to the aerial overpressure peak. A prediction model is built upon this assumption. Secondary flow patterns are observed after the lead. A theory on how the second shock observed in experiments forms is exposed thanks to an analogy with numerical simulation. The phase change dynamics are also discussed thanks to a window in the vessel. Ground loading measurements are finally presented and discussed to give insight into the order of magnitude of the force. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=phase%20change" title="phase change">phase change</a>, <a href="https://publications.waset.org/abstracts/search?q=superheated%20state" title=" superheated state"> superheated state</a>, <a href="https://publications.waset.org/abstracts/search?q=explosion" title=" explosion"> explosion</a>, <a href="https://publications.waset.org/abstracts/search?q=vapor%20expansion" title=" vapor expansion"> vapor expansion</a>, <a href="https://publications.waset.org/abstracts/search?q=blast" title=" blast"> blast</a>, <a href="https://publications.waset.org/abstracts/search?q=shock%20wave" title=" shock wave"> shock wave</a>, <a href="https://publications.waset.org/abstracts/search?q=pressure%20liquefied%20gas" title=" pressure liquefied gas"> pressure liquefied gas</a> </p> <a href="https://publications.waset.org/abstracts/160413/an-experimental-investigation-on-explosive-phase-change-of-liquefied-propane-during-a-bleve-event" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/160413.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">77</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">977</span> Association of Vitamin D Levels in Obese and Non-Obese Patients with Polycystic Ovarian Syndrome in East Indian Populations</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Dipanshu%20Sur">Dipanshu Sur</a>, <a href="https://publications.waset.org/abstracts/search?q=Ratnabali%20Chakravorty"> Ratnabali Chakravorty</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: Polycystic ovary syndrome (PCOS) is the most common metabolic abnormality such as changes in lipid profile, diabetes, hypertension and metabolic syndrome occurring in women. Hypovitaminsis D was found to be associated with the development of obesity and insulin resistance in women with PCOS. Aim: To evaluate the association of vitamin D levels in obese and non-obese patients with PCOS in an East Indian populations. Methods: A case control study was conducted. It enrolled 100 cases of PCOS based on Rotterdam criteria and 100 ovulatory normal cases matched for their age and BMI. Vitamin D levels were compared in the obese and non-obese PCOS groups and also with the controls. Results: The mean age of subjects was 29.48 ± 3.29 years in the PCOS group and 26.24 ± 2.56 years in the control group. Hypovitaminosis D was present in 75 out of 100 PCOS women (75.0%) and 25 women (25.0%) showed sufficient 25OHD levels ≥30 ng/ml. Women with PCOS had significantly lower total serum calcium (8.4 ± 0.25 mg/dl versus 9.8 ± 0.17 mg/dl in controls), and 25 OHD (21.2 ± 2.56 ng/ml versus 32.6 ± 2.23 ng/ml in control group) than ovulatory normal women. This difference remained significant for both groups after adjustment for BMI. Obese women in both groups had significantly lower concentration of calcium and 25OHD than normal weight patients in this study. Conclusion: Our study shows majority of the patients and controls had vitamin D deficiency and there was significant difference in the vitamin D levels in PCOS group and controls as well as obese and non-obese groups. This may reflect the vitamin D deficiency status of the community. Vitamin D deficiency should demands immediate attention as it is a severe problem among the East Indian population. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=vitamin%20D%20deficiency" title="vitamin D deficiency">vitamin D deficiency</a>, <a href="https://publications.waset.org/abstracts/search?q=polycystic%20ovary%20syndrome" title=" polycystic ovary syndrome"> polycystic ovary syndrome</a>, <a href="https://publications.waset.org/abstracts/search?q=obese" title=" obese"> obese</a>, <a href="https://publications.waset.org/abstracts/search?q=hypovitaminsis%20D" title=" hypovitaminsis D"> hypovitaminsis D</a> </p> <a href="https://publications.waset.org/abstracts/33998/association-of-vitamin-d-levels-in-obese-and-non-obese-patients-with-polycystic-ovarian-syndrome-in-east-indian-populations" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/33998.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">316</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">976</span> Effect of Antioxidant-Rich Nutraceutical on Serum Glucose, Lipid Profile and Oxidative Stress Markers of Salt-Induced Metabolic Syndrome in Rats </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nura%20Lawal">Nura Lawal</a>, <a href="https://publications.waset.org/abstracts/search?q=Lawal%20Suleiman%20Bilbis"> Lawal Suleiman Bilbis</a>, <a href="https://publications.waset.org/abstracts/search?q=Rabiu%20Aliyu%20Umar"> Rabiu Aliyu Umar</a>, <a href="https://publications.waset.org/abstracts/search?q=Anas%20A.%20Sabir"> Anas A. Sabir</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Metabolic syndrome (MS) a high-risk condition involving obesity, dyslipidemia, hypertension, and diabetes mellitus is prevalent in Nigeria. The study aims to formulate an antioxidant-rich nutraceutical from locally available foodstuff (onion, garlic, ginger, tomato, lemon, palm oil, watermelon seeds) and investigate their effects on blood pressure, body weight, serum glucose, lipid profile, insulin and oxidative stress markers in salt-induced rats. The rats were placed on 8% salt diet for 6 weeks and then supplementation and treatment with nutraceutical and nifedipine in the presence of salt diet for additional 4 weeks. Feeding rats with salt diet for 6 weeks increased blood pressure and body weight of the salt-loaded rats relative to control. Significant (P < 0.001) increase in serum blood glucose and lipid profile, and the decrease in high-density lipoprotein-cholesterol (HDL-C) was observed in salt-loaded rats as compared with control. Both supplementation and treatment (nifedipine) lowered the blood pressure but the only supplementation lowered the body weight. Supplementation with nutraceutical resulted in significant (P < 0.001) decrease in the serum blood glucose, lipid profile, malonyldialdehyde (MDA), insulin levels, insulin resistance, and increased HDL-C and antioxidant indices. The percentage protection against atherogenesis was 76.5±2.13%. There is strong positive correlation between blood pressure, body weight and serum blood glucose, lipid profile, markers of oxidative stress and strong negative correlation with HDL-C and antioxidant status. The results suggest that the nutraceuticals are useful in reversing most of the component of metabolic syndrome and might be beneficial in the treatment of patients with metabolic syndrome. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=metabolic%20syndrome" title="metabolic syndrome">metabolic syndrome</a>, <a href="https://publications.waset.org/abstracts/search?q=hypertension" title=" hypertension"> hypertension</a>, <a href="https://publications.waset.org/abstracts/search?q=diabetes%20mallitus" title=" diabetes mallitus"> diabetes mallitus</a>, <a href="https://publications.waset.org/abstracts/search?q=obesity" title=" obesity"> obesity</a> </p> <a href="https://publications.waset.org/abstracts/91363/effect-of-antioxidant-rich-nutraceutical-on-serum-glucose-lipid-profile-and-oxidative-stress-markers-of-salt-induced-metabolic-syndrome-in-rats" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/91363.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">249</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">975</span> Modelling Exchange-Rate Pass-Through: A Model of Oil Prices and Asymmetric Exchange Rate Fluctuations in Selected African Countries</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Fajana%20Sola%20Isaac">Fajana Sola Isaac</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In the last two decades, we have witnessed an increased interest in exchange rate pass-through (ERPT) in developing economies and emerging markets. This is perhaps due to the acknowledged significance of the pattern of exchange rate pass-through as a key instrument in monetary policy design, principally in retort to a shock in exchange rate in literature. This paper analyzed Exchange Rate Pass-Through by A Model of Oil Prices and Asymmetric Exchange Rate Fluctuations in Selected African Countries. The study adopted A Non-Linear Autoregressive Distributed Lag approach using yearly data on Algeria, Burundi, Nigeria and South Africa from 1986 to 2022. The paper found asymmetry in exchange rate pass-through in net oil-importing and net oil-exporting countries in the short run during the period under review. An ERPT exhibited a complete pass-through in the short run in the case of net oil-importing countries but an incomplete pass-through in the case of the net oil-exporting countries that were examined. An extended result revealed a significant impact of oil price shock on exchange rate pass-through to domestic price in the long run only for net oil importing countries. The Wald restriction test also confirms the evidence of asymmetric with the role of oil price acting as an accelerator to exchange rate pass-through to domestic price in the countries examined. The study found the outcome to be very useful for gaining expansive knowledge on the external shock impact on ERPT and could be of critical value for national monetary policy decisions on inflation targeting, especially for countries examined and other developing net oil importers and exporters. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=pass%20through" title="pass through">pass through</a>, <a href="https://publications.waset.org/abstracts/search?q=exchange%20rate" title=" exchange rate"> exchange rate</a>, <a href="https://publications.waset.org/abstracts/search?q=ARDL" title=" ARDL"> ARDL</a>, <a href="https://publications.waset.org/abstracts/search?q=monetary%20policy" title=" monetary policy"> monetary policy</a> </p> <a href="https://publications.waset.org/abstracts/173471/modelling-exchange-rate-pass-through-a-model-of-oil-prices-and-asymmetric-exchange-rate-fluctuations-in-selected-african-countries" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/173471.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">79</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">974</span> Bulk/Hull Cavitation Induced by Underwater Explosion: Effect of Material Elasticity and Surface Curvature</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Wenfeng%20Xie">Wenfeng Xie</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Bulk/hull cavitation evolution induced by an underwater explosion (UNDEX) near a free surface (bulk) or a deformable structure (hull) is numerically investigated using a multiphase compressible ﬂuid solver coupled with a one-ﬂuid cavitation model. A series of two-dimensional computations is conducted with varying material elasticity and surface curvature. Results suggest that material elasticity and surface curvature inﬂuence the peak pressures generated from UNDEX shock and cavitation collapse, as well as the bulk/hull cavitation regions near the surface. Results also show that such effects can be different for bulk cavitation generated from UNDEX-free surface interaction and for hull cavitation generated from UNDEX-structure interaction. More importantly, results demonstrate that shock wave focusing caused by a concave solid surface can lead to a larger cavitation region and thus intensify the cavitation reload. The ﬁndings can be linked to the strength and the direction of reﬂected waves from the structural surface and reﬂected waves from the expanding bubble surface, which are functions of material elasticity and surface curvature. Shockwave focusing effects are also observed for axisymmetric simulations, but the strength of the pressure contours for the axisymmetric simulations is less than those for the 2D simulations due to the difference between the initial shock energy. The current method is limited to two-dimensional or axisymmetric applications. Moreover, the thermal effects are neglected and the liquid is not allowed to sustain tension in the cavitation model. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cavitation" title="cavitation">cavitation</a>, <a href="https://publications.waset.org/abstracts/search?q=UNDEX" title=" UNDEX"> UNDEX</a>, <a href="https://publications.waset.org/abstracts/search?q=fluid-structure%20interaction" title=" fluid-structure interaction"> fluid-structure interaction</a>, <a href="https://publications.waset.org/abstracts/search?q=multiphase" title=" multiphase"> multiphase</a> </p> <a href="https://publications.waset.org/abstracts/98340/bulkhull-cavitation-induced-by-underwater-explosion-effect-of-material-elasticity-and-surface-curvature" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/98340.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">185</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">973</span> Extracorporeal Co2 Removal (Ecco2r): An Option for Treatment for Refractory Hypercapnic Respiratory Failure</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Shweh%20Fern%20Loo">Shweh Fern Loo</a>, <a href="https://publications.waset.org/abstracts/search?q=Jun%20Yin%20Ong"> Jun Yin Ong</a>, <a href="https://publications.waset.org/abstracts/search?q=Than%20Zaw%20Oo"> Than Zaw Oo</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Acute respiratory distress syndrome (ARDS) is a common serious condition of bilateral lung infiltrates that develops secondary to various underlying conditions such as diseases or injuries. ARDS with severe hypercapnia is associated with higher ICU mortality and morbidity. Venovenous Extracorporeal membrane oxygenation (VV-ECMO) support has been established to avert life-threatening hypoxemia and hypercapnic respiratory failure despite optimal conventional mechanical ventilation. However, VV-ECMO is relatively not advisable in particular groups of patients, especially in multi-organ failure, advanced age, hemorrhagic complications and irreversible central nervous system pathology. We presented a case of a 79-year-old Chinese lady without any pre-existing lung disease admitted to our hospital intensive care unit (ICU) after acute presentation of breathlessness and chest pain. After extensive workup, she was diagnosed with rapidly progressing acute interstitial pneumonia with ARDS and hypercapnia respiratory failure. The patient received lung protective strategies of mechanical ventilation and neuromuscular blockage therapy as per clinical guidelines. However, hypercapnia respiratory failure was refractory, and she was deemed not a good candidate for VV-ECMO support given her advanced age and high vasopressor requirements from shock. Alternative therapy with extracorporeal CO2 removal (ECCO2R) was considered and implemented. The patient received 12 days of ECCO2R paired with muscle paralysis, optimization of lung-protective mechanical ventilation and dialysis. Unfortunately, the patient still had refractory hypercapnic respiratory failure with dual vasopressor support despite prolonged therapy. Given failed and futile medical treatment, the family opted for withdrawal of care, a conservative approach, and comfort care, which led to her demise. The effectivity of extracorporeal CO2 removal may depend on disease burden, involvement and severity of the disease. There is insufficient data to make strong recommendations about its benefit-risk ratio for ECCO2R devices, and further studies and data would be required. Nonetheless, ECCO2R can be considered an alternative treatment for refractory hypercapnic respiratory failure patients who are unsuitable for initiating venovenous ECMO. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=extracorporeal%20CO2%20removal%20%28ECCO2R%29" title="extracorporeal CO2 removal (ECCO2R)">extracorporeal CO2 removal (ECCO2R)</a>, <a href="https://publications.waset.org/abstracts/search?q=acute%20respiratory%20distress%20syndrome%20%28ARDS%29" title=" acute respiratory distress syndrome (ARDS)"> acute respiratory distress syndrome (ARDS)</a>, <a href="https://publications.waset.org/abstracts/search?q=acute%20interstitial%20pneumonia%20%28AIP%29" title=" acute interstitial pneumonia (AIP)"> acute interstitial pneumonia (AIP)</a>, <a href="https://publications.waset.org/abstracts/search?q=hypercapnic%20respiratory%20failure" title=" hypercapnic respiratory failure"> hypercapnic respiratory failure</a> </p> <a href="https://publications.waset.org/abstracts/173465/extracorporeal-co2-removal-ecco2r-an-option-for-treatment-for-refractory-hypercapnic-respiratory-failure" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/173465.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">65</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">972</span> Coil-Over Shock Absorbers Compared to Inherent Material Damping</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Carina%20Emminger">Carina Emminger</a>, <a href="https://publications.waset.org/abstracts/search?q=Umut%20D.%20Cakmak"> Umut D. Cakmak</a>, <a href="https://publications.waset.org/abstracts/search?q=Evrim%20Burkut"> Evrim Burkut</a>, <a href="https://publications.waset.org/abstracts/search?q=Rene%20Preuer"> Rene Preuer</a>, <a href="https://publications.waset.org/abstracts/search?q=Ingrid%20Graz"> Ingrid Graz</a>, <a href="https://publications.waset.org/abstracts/search?q=Zoltan%20Major"> Zoltan Major</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Damping accompanies us daily in everyday life and is used to protect (e.g., in shoes) and make our life more comfortable (damping of unwanted motion) and calm (noise reduction). In general, damping is the absorption of energy which is either stored in the material (vibration isolation systems) or changed into heat (vibration absorbers). In case of the last, the damping mechanism can be split in active, passive, as well as semi-active (a combination of active and passive). Active damping is required to enable an almost perfect damping over the whole application range and is used, for instance, in sport cars. In contrast, passive damping is a response of the material due to external loading. Consequently, the material composition has a huge influence on the damping behavior. For elastomers, the material behavior is inherent viscoelastic, temperature, and frequency dependent. However, passive damping is not adjustable during application. Therefore, it is of importance to understand the fundamental viscoelastic behavior and the dissipation capability due to external loading. The objective of this work is to assess the limitation and applicability of viscoelastic material damping for applications in which currently coil-over shock absorbers are utilized. Coil-over shock absorbers are usually made of various mechanical parts and incorporate fluids within the damper. These shock absorbers are well-known and studied in the industry, and when needed, they can be easily adjusted during their product lifetime. In contrary, dampers made of – ideally – a single material are more resource efficient, have an easier serviceability, and are easier manufactured. However, they lack of adaptability and adjustability in service. Therefore, a case study with a remote-controlled sport car was conducted. The original shock absorbers were redesigned, and the spring-dashpot system was replaced by both an elastomer and a thermoplastic-elastomer, respectively. Here, five different formulations of elastomers were used, including a pure and an iron-particle filled thermoplastic poly(urethan) (TPU) and blends of two different poly(dimethyl siloxane) (PDMS). In addition, the TPUs were investigated as full and hollow dampers to investigate the difference between solid and structured material. To get comparative results each material formulation was comprehensively characterized, by monotonic uniaxial compression tests, dynamic thermomechanical analysis (DTMA), and rebound resilience. Moreover, the new material-based shock absorbers were compared with spring-dashpot shock absorbers. The shock absorbers were analyzed under monotonic and cyclic loading. In addition, an impact loading was applied on the remote-controlled car to measure the damping properties in operation. A servo-hydraulic high-speed linear actuator was utilized to apply the loads. The acceleration of the car and the displacement of specific measurement points were recorded while testing by a sensor and high-speed camera, respectively. The results prove that elastomers are suitable in damping applications, but they are temperature and frequency dependent. This is a limitation in applicability of viscous material damper. Feasible fields of application may be in the case of micromobility, like bicycles, e-scooters, and e-skateboards. Furthermore, the viscous material damping could be used to increase the inherent damping of a whole structure, e.g., in bicycle-frames. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=damper%20structures" title="damper structures">damper structures</a>, <a href="https://publications.waset.org/abstracts/search?q=material%20damping" title=" material damping"> material damping</a>, <a href="https://publications.waset.org/abstracts/search?q=PDMS" title=" PDMS"> PDMS</a>, <a href="https://publications.waset.org/abstracts/search?q=TPU" title=" TPU"> TPU</a> </p> <a href="https://publications.waset.org/abstracts/153969/coil-over-shock-absorbers-compared-to-inherent-material-damping" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/153969.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">114</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">971</span> Impact of the Achyranthes aspera (Amaranthaceae) Extracts on the Survival and Histological Architecture of the Midgut Epithelial Tissue of Early Fourth Instars of Aedes aegypti (Diptera: Culicidae)</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Aarti%20Sharma">Aarti Sharma</a>, <a href="https://publications.waset.org/abstracts/search?q=Sarita%20Kumar"> Sarita Kumar</a>, <a href="https://publications.waset.org/abstracts/search?q=Pushplata%20Tripathi"> Pushplata Tripathi </a> </p> <p class="card-text"><strong>Abstract:</strong></p> Aedes aegypti L. is one of the most important insect vectors in the world transmitting several diseases of concern; dengue fever, dengue haemorrhagic fever and yellow fever. Though since ages the control of dengue vector is primarily relied upon the use of synthetic chemical insecticides, the continued and indiscriminate use of insecticides for their control has received wide public apprehension because of multifarious problems including insecticide resistance, resurgence of pest species, environmental pollution, toxic hazards to humans and non-target organisms. These problems have necessitated the need to explore and develop alternative strategies using eco-friendly and bio-degradable plant products. Bio-insecticides, despite being the focus of research nowadays, have not been investigated much regarding their physiological effects on the mosquitoes. Thus, the present studies were carried out to investigate the anti-mosquito potential of the leaf and stem hexane extracts of Achyranthes aspera against early fourth instars of Aedes aegypti L and their effects on the histological architecture of their midgut. The larvicidal bioassays conducted with the A. aspera leaf hexane extracts revealed the respective LC30, LC50 and LC90 values of 66.545 ppm, 82.555 ppm, 139.817 ppm while the assays with stem hexane extracts resulted in respective values of 54.982 ppm, 68.133 ppm, 115.075 ppm. The studies clearly indicate the efficacy of extracts as larvicidal agents against Ae. aegypti, the stem extracts being found more effective than the leaf extracts. When the larvae assayed with extracts were investigated for the modifications in the histo-architecture of the midgut, the studies showed significant damage, shrinkage, distortion and vacuolization of gut tissues and peritrophic membrane causing disintegration of epithelial cells and cytoplasmic organelles; extent of toxicity and damage varied depending upon the concentration and exposure time period. These changes revealed appreciable stomach poison potential of A. aspera extracts against Ae. aegypti larvae, which may have also caused adverse impact on the growth and development of larvae. These effects were also found to be more pronounced with the stem extract than the leaf extract. Our findings may prove significant suggesting the use of A. aspera extract as a bio-insecticide against early fourth instar larvae of Ae. aegypti. Further studies are needed to identify the bioactive component in the extracts and to ascertain the use of component in the fields as anti-mosquito control agent. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Achyranthes%20aspera" title="Achyranthes aspera">Achyranthes aspera</a>, <a href="https://publications.waset.org/abstracts/search?q=Aedes%20aegypti" title=" Aedes aegypti"> Aedes aegypti</a>, <a href="https://publications.waset.org/abstracts/search?q=histological%20architecture" title=" histological architecture"> histological architecture</a>, <a href="https://publications.waset.org/abstracts/search?q=larvicidal" title=" larvicidal"> larvicidal</a>, <a href="https://publications.waset.org/abstracts/search?q=midgut" title=" midgut"> midgut</a>, <a href="https://publications.waset.org/abstracts/search?q=stomach%20poison" title=" stomach poison"> stomach poison</a> </p> <a href="https://publications.waset.org/abstracts/39374/impact-of-the-achyranthes-aspera-amaranthaceae-extracts-on-the-survival-and-histological-architecture-of-the-midgut-epithelial-tissue-of-early-fourth-instars-of-aedes-aegypti-diptera-culicidae" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/39374.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">298</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">970</span> Lower Limb Oedema in Beckwith-Wiedemann Syndrome</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mihai-Ionut%20Firescu">Mihai-Ionut Firescu</a>, <a href="https://publications.waset.org/abstracts/search?q=Mark%20A.%20P.%20Carson"> Mark A. P. Carson</a> </p> <p class="card-text"><strong>Abstract:</strong></p> We present a case of inferior vena cava agenesis (IVCA) associated with bilateral deep venous thrombosis (DVT) in a patient with Beckwith-Wiedemann syndrome (BWS). In adult patients with BWS presenting with bilateral lower limb oedema, specific aetiological factors should be considered. These include cardiomyopathy and intraabdominal tumours. Congenital malformations of the IVC, through causing relative venous stasis, can lead to lower limb oedema either directly or indirectly by favouring lower limb venous thromboembolism; however, they are yet to be reported as an associated feature of BWS. Given its life-threatening potential, the prompt initiation of treatment for bilateral DVT is paramount. In BWS patients, however, this can prove more complicated. Due to overgrowth, the above-average birth weight can continue throughout childhood. In this case, the patient’s weight reached 170 kg, impacting on anticoagulation choice, as direct oral anticoagulants have a limited evidence base in patients with a body mass above 120 kg. Furthermore, the presence of IVCA leads to a long-term increased venous thrombosis risk. Therefore, patients with IVCA and bilateral DVT warrant specialist consideration and may benefit from multidisciplinary team management, with hematology and vascular surgery input. Conclusion: Here, we showcased a rare cause for bilateral lower limb oedema, respectively bilateral deep venous thrombosis complicating IVCA in a patient with Beckwith-Wiedemann syndrome. The importance of this case lies in its novelty, as the association between IVC agenesis and BWS has not yet been described. Furthermore, the treatment of DVT in such situations requires special consideration, taking into account the patient’s weight and the presence of a significant, predisposing vascular abnormality. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Beckwith-Wiedemann%20syndrome" title="Beckwith-Wiedemann syndrome">Beckwith-Wiedemann syndrome</a>, <a href="https://publications.waset.org/abstracts/search?q=bilateral%20deep%20venous%20thrombosis" title=" bilateral deep venous thrombosis"> bilateral deep venous thrombosis</a>, <a href="https://publications.waset.org/abstracts/search?q=inferior%20vena%20cava%20agenesis" title=" inferior vena cava agenesis"> inferior vena cava agenesis</a>, <a href="https://publications.waset.org/abstracts/search?q=venous%20thromboembolism" title=" venous thromboembolism"> venous thromboembolism</a> </p> <a href="https://publications.waset.org/abstracts/131341/lower-limb-oedema-in-beckwith-wiedemann-syndrome" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/131341.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">235</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">969</span> Application of Latent Class Analysis and Self-Organizing Maps for the Prediction of Treatment Outcomes for Chronic Fatigue Syndrome</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ben%20Clapperton">Ben Clapperton</a>, <a href="https://publications.waset.org/abstracts/search?q=Daniel%20Stahl"> Daniel Stahl</a>, <a href="https://publications.waset.org/abstracts/search?q=Kimberley%20Goldsmith"> Kimberley Goldsmith</a>, <a href="https://publications.waset.org/abstracts/search?q=Trudie%20Chalder"> Trudie Chalder</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Chronic fatigue syndrome (CFS) is a condition characterised by chronic disabling fatigue and other symptoms that currently can't be explained by any underlying medical condition. Although clinical trials support the effectiveness of cognitive behaviour therapy (CBT), the success rate for individual patients is modest. Patients vary in their response and little is known which factors predict or moderate treatment outcomes. The aim of the project is to develop a prediction model from baseline characteristics of patients, such as demographics, clinical and psychological variables, which may predict likely treatment outcome and provide guidance for clinical decision making and help clinicians to recommend the best treatment. The project is aimed at identifying subgroups of patients with similar baseline characteristics that are predictive of treatment effects using modern cluster analyses and data mining machine learning algorithms. The characteristics of these groups will then be used to inform the types of individuals who benefit from a specific treatment. In addition, results will provide a better understanding of for whom the treatment works. The suitability of different clustering methods to identify subgroups and their response to different treatments of CFS patients is compared. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=chronic%20fatigue%20syndrome" title="chronic fatigue syndrome">chronic fatigue syndrome</a>, <a href="https://publications.waset.org/abstracts/search?q=latent%20class%20analysis" title=" latent class analysis"> latent class analysis</a>, <a href="https://publications.waset.org/abstracts/search?q=prediction%20modelling" title=" prediction modelling"> prediction modelling</a>, <a href="https://publications.waset.org/abstracts/search?q=self-organizing%20maps" title=" self-organizing maps"> self-organizing maps</a> </p> <a href="https://publications.waset.org/abstracts/90820/application-of-latent-class-analysis-and-self-organizing-maps-for-the-prediction-of-treatment-outcomes-for-chronic-fatigue-syndrome" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/90820.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">226</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">968</span> Effect of Lifestyle Modification for Two Years on Obesity and Metabolic Syndrome Components in Elementary Students: A Community-Based Trial</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Bita%20Rabbani">Bita Rabbani</a>, <a href="https://publications.waset.org/abstracts/search?q=Hossein%20Chiti"> Hossein Chiti</a>, <a href="https://publications.waset.org/abstracts/search?q=Faranak%20Sharifi"> Faranak Sharifi</a>, <a href="https://publications.waset.org/abstracts/search?q=Saeedeh%20Mazloomzadeh"> Saeedeh Mazloomzadeh</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Lifestyle modifications, especially improving nutritional patterns and increasing physical activity, are the most important factors in preventing obesity and metabolic syndrome in children and adolescents. For this purpose, the following interventional study was designed to investigate the effects of educational programs for students, as well as changes in diet and physical activity, on obesity and components of the metabolic syndrome. Methods: This study is part of an interventional research project (elementary school) conducted on all students of Sama schools in Zanjan and Abhar in three levels of elementary, middle, and high school, including 1000 individuals in Zanjan (intervention group) and 1000 individuals (control group) in Abhar in 2011. Interventions were based on educating students, teachers, and parents, changes in food services, and physical activity. We primarily measured anthropometric indices, fasting blood sugar, lipid profiles, and blood pressure and completed standard nutrition and physical activity questionnaires. Also, blood insulin levels were randomly measured in a number of students. Data analysis was done by SPSS software version 16.0. Results: Overall, 589 individuals (252 male, 337 female) entered the case group, and 803 individuals (344 male, 459 female) entered the control group. After two years of intervention, mean waist circumference (63.8 ± 10.9) and diastolic BP (63.8 ± 10.4) were significantly lower; however, mean systolic BP (10.1.0 ± 12.5), food score (25.0 ± 5.0) and drinking score (12.1 ± 2.3) were higher in the intervention group (p<0.001). Comparing components of metabolic syndrome between the second year and at time of recruitment within the intervention group showed that although number of overweight/obese individuals, individuals with hypertriglyceridemia and high LDL increased, abdominal obesity, high BP, hyperglycemia, and insulin resistance decreased (p<0.001). On the other hand, in the control group, number of individuals with high BP increased significantly. Conclusion: The prevalence of abdominal obesity and hypertension, which are two major components of metabolic syndrome, are much higher in our study than in other regions of country. However, interventions for modification of diet and increase in physical activity are effective in lowering their prevalence. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=metabolic%20syndrome" title="metabolic syndrome">metabolic syndrome</a>, <a href="https://publications.waset.org/abstracts/search?q=obesity" title=" obesity"> obesity</a>, <a href="https://publications.waset.org/abstracts/search?q=life%20style" title=" life style"> life style</a>, <a href="https://publications.waset.org/abstracts/search?q=nutrition" title=" nutrition"> nutrition</a>, <a href="https://publications.waset.org/abstracts/search?q=hypertension" title=" hypertension"> hypertension</a> </p> <a href="https://publications.waset.org/abstracts/166724/effect-of-lifestyle-modification-for-two-years-on-obesity-and-metabolic-syndrome-components-in-elementary-students-a-community-based-trial" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/166724.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">67</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">967</span> Somatosensory-Evoked Blink Reflex in Peripheral Facial Palsy</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sarah%20Sayed%20El-%20Tawab">Sarah Sayed El- Tawab</a>, <a href="https://publications.waset.org/abstracts/search?q=Emmanuel%20Kamal%20Azix%20Saba"> Emmanuel Kamal Azix Saba</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Objectives: Somatosensory blink reflex (SBR) is an eye blink response obtained from electrical stimulation of peripheral nerves or skin area of the body. It has been studied in various neurological diseases as well as among healthy subjects in different population. We designed this study to detect SBR positivity in patients with facial palsy and patients with post facial syndrome, to relate the facial palsy severity and the presence of SBR, and to associate between trigeminal BR changes and SBR positivity in peripheral facial palsy patients. Methods: 50 patients with peripheral facial palsy and post-facial syndrome 31 age and gender matched healthy volunteers were enrolled to this study. Facial motor conduction studies, trigeminal BR, and SBR were studied in all. Results: SBR was elicited in 67.7% of normal subjects, in 68% of PFS group, and in 32% of PFP group. On the non-paralytic side SBR was found in 28% by paralyzed side stimulation and in 24% by healthy side stimulation among PFP patients. For PFS group SBR was found on the non- paralytic side in 48%. Bilateral SBR elicitability was higher than its unilateral elicitability. Conclusion: Increased brainstem interneurons excitability is not essential to generate SBR. The hypothetical sensory-motor gating mechanism is responsible for SBR generation. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=somatosensory%20evoked%20blink%20reflex" title="somatosensory evoked blink reflex">somatosensory evoked blink reflex</a>, <a href="https://publications.waset.org/abstracts/search?q=post%20facial%20syndrome" title=" post facial syndrome"> post facial syndrome</a>, <a href="https://publications.waset.org/abstracts/search?q=blink%20reflex" title=" blink reflex"> blink reflex</a>, <a href="https://publications.waset.org/abstracts/search?q=enchanced%20gain" title=" enchanced gain"> enchanced gain</a> </p> <a href="https://publications.waset.org/abstracts/18913/somatosensory-evoked-blink-reflex-in-peripheral-facial-palsy" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/18913.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">619</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">966</span> Clinical Signs of Neonatal Calves in Experimental Colisepticemia</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Samad%20Lotfollahzadeh">Samad Lotfollahzadeh</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Escherichia coli (E.coli) is the most isolated bacteria from blood circulation of septicemic calves. Given the prevalence of septicemia in animals and its economic importance in veterinary practice, better understanding of changes in clinical signs following disease, may contribute to early detection of the disorder. The present study has been carried out to detect changes of clinical signs in induced sepsis in calves with E.coli. Colisepticemia has been induced in 10 twenty-day old healthy Holstein- Frisian calves with intravenous injection of 1.5 X 109 colony forming units (cfu) of O111: H8 strain of E.coli. Clinical signs including rectal temperature, heart rate, respiratory rate, shock, appetite, sucking reflex, feces consistency, general behavior, dehydration and standing ability were recorded in experimental calves during 24 hours after induction of colisepticemia. Blood culture was also carried out from calves four times during the experiment. ANOVA with repeated measure is used to see changes of calves’ clinical signs to experimental colisepticemia, and values of P≤ 0.05 was considered statistically significant. Mean values of rectal temperature and heart rate as well as median values of respiratory rate, appetite, suckling reflex, standing ability and feces consistency of experimental calves increased significantly during the study (P<0.05). In the present study, median value of shock score was not significantly increased in experimental calves (P> 0.05). The results of present study showed that total score of clinical signs in calves with experimental colisepticemia increased significantly, although the score of some clinical signs such as shock did not change significantly. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=calves" title="calves">calves</a>, <a href="https://publications.waset.org/abstracts/search?q=clinical%20signs%20scoring" title=" clinical signs scoring"> clinical signs scoring</a>, <a href="https://publications.waset.org/abstracts/search?q=E.%20coli%20O111%3AH8" title=" E. coli O111:H8"> E. coli O111:H8</a>, <a href="https://publications.waset.org/abstracts/search?q=experimental%20colisepticemia" title=" experimental colisepticemia"> experimental colisepticemia</a> </p> <a href="https://publications.waset.org/abstracts/37741/clinical-signs-of-neonatal-calves-in-experimental-colisepticemia" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/37741.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">376</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">965</span> Acute Kidney Injury in Severe Trauma Patients: Clinical Presentation and Risk Factor Analysis</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Inkyong%20Yi">Inkyong Yi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Acute kidney injury (AKI) in trauma patients is known to be associated with multiple factors, especially shock and consequent inadequate renal perfusion, yet its clinical presentation is little known in severe trauma patients. Our aim was to investigate the clinical presentation of acute kidney injury and its outcome in severe trauma patients at a level I trauma center. A total of 93 consecutive adult trauma patients with an injury severity score (ISS) of more than 15 were analyzed retrospectively from our Level I trauma center data base. Patients with direct renal injury were excluded. Patients were dichotomized into two groups, according to the presence of AKI. Various clinical parameters were compared between two groups, with Student’s T test and Mann-Whitney’s U test. The AKI group was further dichotomized into patients who recovered within seven days, and those who required more than 7days for recovery or those who did not recover at all. Various clinical parameters associated with outcome were further analyzed. Patients with AKI (n=33, 35%) presented with significantly higher age (61.4±17.3 vs. 45.4±17.3, p < 0.0001), incidence of comorbidities (hypertension; 51.5% vs. 13.3%, OR 6.906 95%CI 2.515-18.967, diabetes; 27.3% vs. 6.7%, OR 5.250, 95%CI 1.472-18.722), odds of head and neck trauma (69.7% vs. 41.7%, OR 3.220, 95%CI 1.306-7.942) and presence of shock during emergency room care (66.7% vs 21.7% OR 7.231, 95%CI, 2.798-18.687). Among AKI patients, patients who recovered within 1 week showed lower peak lactate (4.7mmol/L, 95%CI 2.9-6.5 vs 7.3mmol/L, 95%CI 5.0-9.6, p < 0.0287), lesser units of transfusion during first 24 hours (pRBC; 20.4unit, 95%CI 12.5-28.3 vs. 58.9unit, 95%CI 39.4-78.5, p=0.0003, FFP; 16.6unit, 95%CI 6.8-26.4 vs. 56.1unit, 95%CI 26.9-85.2, p=0.0027). In severe trauma patients, patients with AKI showed different clinical presentations and worse outcomes. Initial presence of shock and higher DIC profiles may be important risk factors for AKI in severe trauma patients. In patients with AKI, peak lactate level and amounts of transfusion are related to recovery. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=acute%20kidney%20injury" title="acute kidney injury">acute kidney injury</a>, <a href="https://publications.waset.org/abstracts/search?q=lactate" title=" lactate"> lactate</a>, <a href="https://publications.waset.org/abstracts/search?q=transfusion" title=" transfusion"> transfusion</a>, <a href="https://publications.waset.org/abstracts/search?q=trauma" title=" trauma"> trauma</a> </p> <a href="https://publications.waset.org/abstracts/80039/acute-kidney-injury-in-severe-trauma-patients-clinical-presentation-and-risk-factor-analysis" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/80039.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">203</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">964</span> Kinetics of Acetaminophen Based Oscillatory Chemical Reaction with and without Ferroin as Catalyst: An Inorganic Prototype Model for Paracetamol-Ethanol Syndrome</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nadeem%20Bashir">Nadeem Bashir</a>, <a href="https://publications.waset.org/abstracts/search?q=Ghulam%20Mustafa%20Peerzada"> Ghulam Mustafa Peerzada</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The present study pertains to the nonlinear behavior of acetaminophen based uncatalyzed Belousov-Zhabotinsky (BZ) oscillator and its dynamics in the presence of Ferroin as the catalyst. The role of free metal ions as catalysts was examined and the results compared with corresponding complexed catalysts. Free metal ions were found to be sluggish with respect to the evolution of the oscillatory regime as compared to complexed ones. Effect of change of the ligand moiety of the catalyst complex on the oscillatory parameters was monitored. Since ethanol potentiates the hepatotoxicity caused by acetaminophen in-vivo, it is thought to understand this interaction by virtue of causing perturbation of the acetaminophen based oscillator with different concentrations of the ethanol with and without ferroin as the catalyst. Another dimension to the ethanol effect was added by perturbation of the system with ethanol at different stages of the reaction so as to get an idea whether it is acetaminophen or some reactive intermediate generated in the reaction system which reacts with ethanol. Further, the ferroin-catalyzed oscillator is taken as a prototype inorganic model of the acetaminophen-ethanol syndrome, as ferroin and HOBr were inorganic replacements to Cyt P450 and NADPH in the alcohol metabolism. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Belousov-Zhabotinsky%20reaction" title="Belousov-Zhabotinsky reaction">Belousov-Zhabotinsky reaction</a>, <a href="https://publications.waset.org/abstracts/search?q=ferroin" title=" ferroin"> ferroin</a>, <a href="https://publications.waset.org/abstracts/search?q=Paracetamol-Ethanol%20syndrome" title=" Paracetamol-Ethanol syndrome"> Paracetamol-Ethanol syndrome</a>, <a href="https://publications.waset.org/abstracts/search?q=kinetics" title=" kinetics"> kinetics</a> </p> <a href="https://publications.waset.org/abstracts/64014/kinetics-of-acetaminophen-based-oscillatory-chemical-reaction-with-and-without-ferroin-as-catalyst-an-inorganic-prototype-model-for-paracetamol-ethanol-syndrome" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/64014.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">531</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">963</span> Expectation for Professionalism Effects Reality Shock: A Qualitative And Quantitative Study of Reality Shock among New Human Service Professionals</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Hiromi%20Takafuji">Hiromi Takafuji</a> </p> <p class="card-text"><strong>Abstract:</strong></p> It is a well-known fact that health care and welfare are the foundation of human activities, and human service professionals such as nurses and child care workers support these activities. COVID-19 pandemic has made the severity of the working environment in these fields even more known. It is high time to discuss the work of human service workers for the sustainable development of the human environment. Early turnover has been recognized as a long-standing issue in these fields. In Japan, the attrition rate within three years of graduation for these occupations has remained high at about 40% for more than 20 years. One of the reasons for this is Reality Shock: RS, which refers to the stress caused by the gap between pre-employment expectations and the post-employment reality experienced by new workers. The purpose of this study was to academically elucidate the mechanism of RS among human service professionals and to contribute to countermeasures against it. Firstly, to explore the structure of the relationship between professionalism and workers' RS, an exploratory interview survey was conducted and analyzed by text mining and content analysis. The results showed that the expectation of professionalism influences RS as a pre-employment job expectation. Next, the expectations of professionalism were quantified and categorized, and the responses of a total of 282 human service work professionals, nurses, child care workers, and caregivers; were finalized for data analysis. The data were analyzed using exploratory factor analysis, confirmatory factor analysis, multiple regression analysis, and structural equation modeling techniques. The results revealed that self-control orientation and authority orientation by qualification had a direct positive significant impact on RS. On the other hand, interpersonal helping orientation and altruistic orientation were found to have a direct negative significant impact and an indirect positive significant impact on RS.; we were able to clarify the structure of work expectations that affect the RS of welfare professionals, which had not been clarified in previous studies. We also explained the limitations, practical implications, and directions for future research. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=human%20service%20professional" title="human service professional">human service professional</a>, <a href="https://publications.waset.org/abstracts/search?q=new%20hire%20turnover" title=" new hire turnover"> new hire turnover</a>, <a href="https://publications.waset.org/abstracts/search?q=SEM" title=" SEM"> SEM</a>, <a href="https://publications.waset.org/abstracts/search?q=reality%20shock" title=" reality shock"> reality shock</a> </p> <a href="https://publications.waset.org/abstracts/147137/expectation-for-professionalism-effects-reality-shock-a-qualitative-and-quantitative-study-of-reality-shock-among-new-human-service-professionals" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/147137.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">99</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">962</span> Intracranial Hypertension without CVST in Apla Syndrome: An Unique Association</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Camelia%20Porey">Camelia Porey</a>, <a href="https://publications.waset.org/abstracts/search?q=Binaya%20Kumar%20Jaiswal"> Binaya Kumar Jaiswal</a> </p> <p class="card-text"><strong>Abstract:</strong></p> BACKGROUND: Antiphospholipid antibody (APLA) syndrome is an autoimmune disorder predisposing to thrombotic complications affecting CNS either by arterial vasooclusion or venous thrombosis. Cerebral venous sinus thrombosis (CVST) secondarily causes raised intracranial pressure (ICP). However, intracranial hypertension without evidence of CVST is a rare entity. Here we present two cases of elevated ICP with absence of identifiable CVST. CASE SUMMARY: Case 1, 28-year female had a 2 months history of holocranial headache followed by bilateral painless vision loss reaching lack of light perception over 20 days. CSF opening pressure was elevated. Fundoscopy showed bilateral grade 4 papilledema. MRI revealed a partially empty sella with bilateral optic nerve tortuosity. Idiopathic intracranial hypertension (IIH) was diagnosed. With acetazolamide, there was complete resolution of the clinical and radiological abnormalities. 5 months later she presented with acute onset right-sided hemiparesis. MRI was suggestive of acute left MCA infarct.MR venogram was normal. APLA came positive with high titres of Anticardiolipin and Beta 2 glycoprotein both IgG and IgM. Case 2, 23-year female, presented with headache and diplopia of 2 months duration. CSF pressure was elevated and Grade 3 papilledema was seen. MRI showed bilateral optic nerve hyperintensities with nerve head protrusion with normal MRV. APLA profile showed elevated beta 2 glycoprotein IgG and IgA. CONCLUSION: This is an important non thrombotic complication of APLA syndrome and requires further large-scale study for insight into the pathogenesis and early recognition to avoid future complications. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=APLA%20syndrome" title="APLA syndrome">APLA syndrome</a>, <a href="https://publications.waset.org/abstracts/search?q=idiopathic%20intracranial%20hypertension" title=" idiopathic intracranial hypertension"> idiopathic intracranial hypertension</a>, <a href="https://publications.waset.org/abstracts/search?q=MR%20venogram" title=" MR venogram"> MR venogram</a>, <a href="https://publications.waset.org/abstracts/search?q=papilledema" title=" papilledema"> papilledema</a> </p> <a href="https://publications.waset.org/abstracts/147679/intracranial-hypertension-without-cvst-in-apla-syndrome-an-unique-association" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/147679.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">176</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">961</span> Autoimmune Diseases Associated with Primary Biliary Cirrhosis: A Retrospective Study of 51 Patients</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Soumaya%20Mrabet">Soumaya Mrabet</a>, <a href="https://publications.waset.org/abstracts/search?q=Imen%20Akkari"> Imen Akkari</a>, <a href="https://publications.waset.org/abstracts/search?q=Amira%20Atig"> Amira Atig</a>, <a href="https://publications.waset.org/abstracts/search?q=Elhem%20Ben%20Jazia"> Elhem Ben Jazia</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: Primary biliary cirrhosis (PBC) is a cholestatic cholangitis of unknown etiology. It is frequently associated with autoimmune diseases, which explains their systematic screening. The aim of our study was to determine the prevalence and the type of autoimmune disorders associated with PBC and to assess their impact on the prognosis of the disease. Material and methods: It is a retrospective study over a period of 16 years (2000-2015) including all patients followed for PBC. In all these patients we have systematically researched: dysthyroidism (thyroid balance, antithyroid autoantibodies), type 1 diabetes, dry syndrome (ophthalmologic examination, Schirmer test and lip biopsy in case of Presence of suggestive clinical signs), celiac disease(celiac disease serology and duodenal biopsies) and dermatological involvement (clinical examination). Results: Fifty-one patients (50 women and one men) followed for PBC were collected. The Mean age was 54 years (37-77 years). Among these patients, 30 patients(58.8%) had at least one autoimmune disease associated with PBC. The discovery of these autoimmune diseases preceded the diagnosis of PBC in 8 cases (26.6%) and was concomitant, through systematic screening, in the remaining cases. Autoimmune hepatitis was found in 12 patients (40%), defining thus an overlap syndrome. Other diseases were Hashimoto's thyroiditis (n = 10), dry syndrome (n = 7), Gougerot Sjogren syndrome (n=6), celiac disease (n = 3), insulin-dependent diabetes (n = 1), scleroderma (n = 1), rheumatoid arthritis (n = 1), Biermer Anemia (n=1) and Systemic erythematosus lupus (n=1). The two groups of patients with PBC with or without associated autoimmune disorders were comparable for bilirubin levels, Child-Pugh score, and response to treatment. Conclusion: In our series, the prevalence of autoimmune diseases in PBC was 58.8%. These diseases were dominated by autoimmune hepatitis and Hashimoto's thyroiditis. Even if their association does not seem to alter the prognosis, screening should be systematic in order to institute an early and adequate management. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=autoimmune%20diseases" title="autoimmune diseases">autoimmune diseases</a>, <a href="https://publications.waset.org/abstracts/search?q=autoimmune%20hepatitis" title=" autoimmune hepatitis"> autoimmune hepatitis</a>, <a href="https://publications.waset.org/abstracts/search?q=primary%20biliary%20cirrhosis" title=" primary biliary cirrhosis"> primary biliary cirrhosis</a>, <a href="https://publications.waset.org/abstracts/search?q=prognosis" title=" prognosis"> prognosis</a> </p> <a href="https://publications.waset.org/abstracts/66030/autoimmune-diseases-associated-with-primary-biliary-cirrhosis-a-retrospective-study-of-51-patients" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/66030.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">276</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">960</span> Development of Peptide Inhibitors against Dengue Virus Infection by in Silico Design</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Aussara%20Panya">Aussara Panya</a>, <a href="https://publications.waset.org/abstracts/search?q=Nunghathai%20Sawasdee"> Nunghathai Sawasdee</a>, <a href="https://publications.waset.org/abstracts/search?q=Mutita%20Junking"> Mutita Junking</a>, <a href="https://publications.waset.org/abstracts/search?q=Chatchawan%20Srisawat"> Chatchawan Srisawat</a>, <a href="https://publications.waset.org/abstracts/search?q=Kiattawee%20Choowongkomon"> Kiattawee Choowongkomon</a>, <a href="https://publications.waset.org/abstracts/search?q=Pa-Thai%20Yenchitsomanus"> Pa-Thai Yenchitsomanus</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Dengue virus (DENV) infection is a global public health problem with approximately 100 million infected cases a year. Presently, there is no approved vaccine or effective drug available; therefore, the development of anti-DENV drug is urgently needed. The clinical reports revealing the positive association between the disease severity and viral titer has been reported previously suggesting that the anti-DENV drug therapy can possibly ameliorate the disease severity. Although several anti-DENV agents showed inhibitory activities against DENV infection, to date none of them accomplishes clinical use in the patients. The surface envelope (E) protein of DENV is critical for the viral entry step, which includes attachment and membrane fusion; thus, the blocking of envelope protein is an attractive strategy for anti-DENV drug development. To search the safe anti-DENV agent, this study aimed to search for novel peptide inhibitors to counter DENV infection through the targeting of E protein using a structure-based in silico design. Two selected strategies has been used including to identify the peptide inhibitor which interfere the membrane fusion process whereby the hydrophobic pocket on the E protein was the target, the destabilization of virion structure organization through the disruption of the interaction between the envelope and membrane proteins, respectively. The molecular docking technique has been used in the first strategy to search for the peptide inhibitors that specifically bind to the hydrophobic pocket. The second strategy, the peptide inhibitor has been designed to mimic the ectodomain portion of membrane protein to disrupt the protein-protein interaction. The designed peptides were tested for the effects on cell viability to measure the toxic to peptide to the cells and their inhibitory assay to inhibit the DENV infection in Vero cells. Furthermore, their antiviral effects on viral replication, intracellular protein level and viral production have been observed by using the qPCR, cell-based flavivirus immunodetection and immunofluorescence assay. None of tested peptides showed the significant effect on cell viability. The small peptide inhibitors achieved from molecular docking, Glu-Phe (EF), effectively inhibited DENV infection in cell culture system. Its most potential effect was observed for DENV2 with a half maximal inhibition concentration (IC50) of 96 μM, but it partially inhibited other serotypes. Treatment of EF at 200 µM on infected cells also significantly reduced the viral genome and protein to 83.47% and 84.15%, respectively, corresponding to the reduction of infected cell numbers. An additional approach was carried out by using peptide mimicking membrane (M) protein, namely MLH40. Treatment of MLH40 caused the reduction of foci formation in four individual DENV serotype (DENV1-4) with IC50 of 24-31 μM. Further characterization suggested that the MLH40 specifically blocked viral attachment to host membrane, and treatment with 100 μM could diminish 80% of viral attachment. In summary, targeting the hydrophobic pocket and M-binding site on the E protein by using the peptide inhibitors could inhibit DENV infection. The results provide proof of-concept for the development of antiviral therapeutic peptide inhibitors to counter DENV infection through the use of a structure-based design targeting conserved viral protein. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=dengue%20virus" title="dengue virus">dengue virus</a>, <a href="https://publications.waset.org/abstracts/search?q=dengue%20virus%20infection" title=" dengue virus infection"> dengue virus infection</a>, <a href="https://publications.waset.org/abstracts/search?q=drug%20design" title=" drug design"> drug design</a>, <a href="https://publications.waset.org/abstracts/search?q=peptide%20inhibitor" title=" peptide inhibitor"> peptide inhibitor</a> </p> <a href="https://publications.waset.org/abstracts/37420/development-of-peptide-inhibitors-against-dengue-virus-infection-by-in-silico-design" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/37420.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">357</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">959</span> Analysis of Earthquake Potential and Shock Level Scenarios in South Sulawesi</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Takhul%20Bakhtiar">Takhul Bakhtiar</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In South Sulawesi Province, there is an active Walanae Fault causing this area to frequently experience earthquakes. This study aims to determine the level of seismicity of the earthquake in order to obtain the potential for earthquakes in the future. The estimation of the potential for earthquakes is then made a scenario model determine the estimated level of shocks as an effort to mitigate earthquake disasters in the region. The method used in this study is the Gutenberg Richter Method through the statistical likelihood approach. This study used earthquake data in the South Sulawesi region in 1972 - 2022. The research location is located at the coordinates of 3.5° – 5.5° South Latitude and 119.5° – 120.5° East Longitude and divided into two segments, namely the northern segment at the coordinates of 3.5° – 4.5° South Latitude and 119,5° – 120,5° East Longitude then the southern segment with coordinates of 4.5° – 5.5° South Latitude and 119,5° – 120.5° East Longitude. This study uses earthquake parameters with a magnitude > 1 and a depth < 50 km. The results of the analysis show that the potential for earthquakes in the next ten years with a magnitude of M = 7 in the northern segment is estimated at 98.81% with an estimated shock level of VI-VII MMI around the cities of Pare-Pare, Barru, Pinrang and Soppeng then IV - V MMI in the cities of Bulukumba, Selayar, Makassar and Gowa. In the southern segment, the potential for earthquakes in the next ten years with a magnitude of M = 7 is estimated at 32.89% with an estimated VI-VII MMI shock level in the cities of Bulukumba, Selayar, Makassar and Gowa, then III-IV MMI around the cities of Pare-Pare, Barru, Pinrang and Soppeng. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Gutenberg%20Richter" title="Gutenberg Richter">Gutenberg Richter</a>, <a href="https://publications.waset.org/abstracts/search?q=likelihood%20method" title=" likelihood method"> likelihood method</a>, <a href="https://publications.waset.org/abstracts/search?q=seismicity" title=" seismicity"> seismicity</a>, <a href="https://publications.waset.org/abstracts/search?q=shakemap%20and%20MMI%20scale" title=" shakemap and MMI scale"> shakemap and MMI scale</a> </p> <a href="https://publications.waset.org/abstracts/147589/analysis-of-earthquake-potential-and-shock-level-scenarios-in-south-sulawesi" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/147589.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">120</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">958</span> A Systematic Review on Measuring the Physical Activity Level and Pattern in Persons with Chronic Fatigue Syndrome</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Kuni%20Vergauwen">Kuni Vergauwen</a>, <a href="https://publications.waset.org/abstracts/search?q=Ivan%20P.%20J.%20Huijnen"> Ivan P. J. Huijnen</a>, <a href="https://publications.waset.org/abstracts/search?q=Astrid%20Depuydt"> Astrid Depuydt</a>, <a href="https://publications.waset.org/abstracts/search?q=Jasmine%20Van%20Regenmortel"> Jasmine Van Regenmortel</a>, <a href="https://publications.waset.org/abstracts/search?q=Mira%20Meeus"> Mira Meeus</a> </p> <p class="card-text"><strong>Abstract:</strong></p> A lower activity level and imbalanced activity pattern are frequently observed in persons with chronic fatigue syndrome (CFS) / myalgic encephalomyelitis (ME) due to debilitating fatigue and post-exertional malaise (PEM). Identification of measurement instruments to evaluate the activity level and pattern is therefore important. The objective is to identify measurement instruments suited to evaluate the activity level and/or pattern in patients with CFS/ME and review their psychometric properties. A systematic literature search was performed in the electronic databases PubMed and Web of Science until 12 October 2016. Articles including relevant measurement instruments were identified and included for further analysis. The psychometric properties of relevant measurement instruments were extracted from the included articles and rated based on the COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) checklist. The review was performed and reported according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. A total of 49 articles and 15 unique measurement instruments were found, but only three instruments were evaluated in patients with CFS/ME: the Chronic Fatigue Syndrome-Activity Questionnaire (CFS-AQ), Activity Pattern Interview (API) and International Physical Activity Questionnaire-Short Form (IPAQ-SF), three self-report instruments measuring the physical activity level. The IPAQ-SF, CFS-AQ and API are all equally capable of evaluating the physical activity level, but none of the three measurement instruments are optimal to use. No studies about the psychometric properties of activity monitors in patients with CFS/ME were found, although they are often used as the gold standard to measure the physical activity pattern. More research is needed to evaluate the psychometric properties of existing instruments, including the use of activity monitors. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=chronic%20fatigue%20syndrome" title="chronic fatigue syndrome">chronic fatigue syndrome</a>, <a href="https://publications.waset.org/abstracts/search?q=data%20collection" title=" data collection"> data collection</a>, <a href="https://publications.waset.org/abstracts/search?q=physical%20activity" title=" physical activity"> physical activity</a>, <a href="https://publications.waset.org/abstracts/search?q=psychometrics" title=" psychometrics"> psychometrics</a> </p> <a href="https://publications.waset.org/abstracts/57390/a-systematic-review-on-measuring-the-physical-activity-level-and-pattern-in-persons-with-chronic-fatigue-syndrome" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/57390.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">227</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">957</span> Numerical Investigation of Effect of Throat Design on the Performance of a Rectangular Ramjet Intake </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Subrat%20Partha%20Sarathi%20Pattnaik">Subrat Partha Sarathi Pattnaik</a>, <a href="https://publications.waset.org/abstracts/search?q=Rajan%20N.K.S."> Rajan N.K.S.</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Integrated rocket ramjet engines are highly suitable for long range missile applications. Designing the fixed geometry intakes for such missiles that can operate efficiently over a range of operating conditions is a highly challenging task. Hence, the present study aims to evaluate the effect of throat design on the performance of a rectangular mixed compression intake for operation in the Mach number range of 1.8 – 2.5. The analysis has been carried out at four different Mach numbers of 1.8, 2, 2.2, 2.5 and two angle-of-attacks of +5 and +10 degrees. For the throat design, three different throat heights have been considered, one corresponding to a 3- external shock design and two heights corresponding to a 2-external shock design leading to different internal contraction ratios. The on-design Mach number for the study is M 2.2. To obtain the viscous flow field in the intake, the theoretical designs have been considered for computational fluid dynamic analysis. For which Favre averaged Navier- Stokes (FANS) equations with two equation SST k-w model have been solved. The analysis shows that for zero angle of attack at on-design and high off-design Mach number operations the three-ramp design leads to a higher total pressure recovery (TPR) compared to the two-ramp design at both contraction ratios maintaining same mass flow ratio (MFR). But at low off-design Mach numbers the total pressure shows an opposite trend that is maximum for the two-ramp low contraction ratio design due to lower shock loss across the external shocks similarly the MFR is higher for low contraction ratio design as the external ramp shocks move closer to the cowl. At both the angle of attack conditions and complete range of Mach numbers the total pressure recovery and mass flow ratios are highest for two ramp low contraction design due to lower stagnation pressure loss across the detached bow shock formed at the ramp and lower mass spillage. Hence, low contraction design is found to be suitable for higher off-design performance. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=internal%20contraction%20ratio" title="internal contraction ratio">internal contraction ratio</a>, <a href="https://publications.waset.org/abstracts/search?q=mass%20flow%20ratio" title=" mass flow ratio"> mass flow ratio</a>, <a href="https://publications.waset.org/abstracts/search?q=mixed%20compression%20intake" title=" mixed compression intake"> mixed compression intake</a>, <a href="https://publications.waset.org/abstracts/search?q=performance" title=" performance"> performance</a>, <a href="https://publications.waset.org/abstracts/search?q=supersonic%20flows" title=" supersonic flows "> supersonic flows </a> </p> <a href="https://publications.waset.org/abstracts/120058/numerical-investigation-of-effect-of-throat-design-on-the-performance-of-a-rectangular-ramjet-intake" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/120058.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">108</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">956</span> Optimal Continuous Scheduled Time for a Cumulative Damage System with Age-Dependent Imperfect Maintenance</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Chin-Chih%20Chang">Chin-Chih Chang</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Many manufacturing systems suffer failures due to complex degradation processes and various environment conditions such as random shocks. Consider an operating system is subject to random shocks and works at random times for successive jobs. When successive jobs often result in production losses and performance deterioration, it would be better to do maintenance or replacement at a planned time. A preventive replacement (PR) policy is presented to replace the system before a failure occurs at a continuous time T. In such a policy, the failure characteristics of the system are designed as follows. Each job would cause a random amount of additive damage to the system, and the system fails when the cumulative damage has exceeded a failure threshold. Suppose that the deteriorating system suffers one of the two types of shocks with age-dependent probabilities: type-I (minor) shock is rectified by a minimal repair, or type-II (catastrophic) shock causes the system to fail. A corrective replacement (CR) is performed immediately when the system fails. In summary, a generalized maintenance model to scheduling replacement plan for an operating system is presented below. PR is carried out at time T, whereas CR is carried out when any type-II shock occurs and the total damage exceeded a failure level. The main objective is to determine the optimal continuous schedule time of preventive replacement through minimizing the mean cost rate function. The existence and uniqueness of optimal replacement policy are derived analytically. It can be seen that the present model is a generalization of the previous models, and the policy with preventive replacement outperforms the one without preventive replacement. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=preventive%20replacement" title="preventive replacement">preventive replacement</a>, <a href="https://publications.waset.org/abstracts/search?q=working%20time" title=" working time"> working time</a>, <a href="https://publications.waset.org/abstracts/search?q=cumulative%20damage%20model" title=" cumulative damage model"> cumulative damage model</a>, <a href="https://publications.waset.org/abstracts/search?q=minimal%20repair" title=" minimal repair"> minimal repair</a>, <a href="https://publications.waset.org/abstracts/search?q=imperfect%20maintenance" title=" imperfect maintenance"> imperfect maintenance</a>, <a href="https://publications.waset.org/abstracts/search?q=optimization" title=" optimization"> optimization</a> </p> <a href="https://publications.waset.org/abstracts/68581/optimal-continuous-scheduled-time-for-a-cumulative-damage-system-with-age-dependent-imperfect-maintenance" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/68581.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">363</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">955</span> Enhancement of Material Removal Rate of Complex Featured Surfaces in Vibratory Finishing</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Kunal%20Ahluwalia">Kunal Ahluwalia</a>, <a href="https://publications.waset.org/abstracts/search?q=Ampara%20Aramcharoen"> Ampara Aramcharoen</a>, <a href="https://publications.waset.org/abstracts/search?q=Chan%20Wai%20Luen"> Chan Wai Luen</a>, <a href="https://publications.waset.org/abstracts/search?q=Swee%20Hock%20Yeo"> Swee Hock Yeo</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The different process engineering applications of vibratory finishing technology have led to its versatile use in the development of aviation components. The most noteworthy applications of vibratory finishing include deburring and imparting the required surface finish. In this paper, vibratory finishing has been used to study its effectiveness in removal of laser shock peened (LSP) layers from Titanium workpieces. A vibratory trough operating at a frequency of 25 Hz, amplitude 3.5 mm and titanium specimens (Ti-6Al-4V, Grade 5) of dimensions 50 x 50 x 10 mm³ were utilized for the experiments. A vibrating fixture operating at 200 Hz was used to provide vibration to the test piece and was immersed in the vibratory trough. It was evident that there is an increase in efficiency of removal of the complex featured layer and smoother surface finish with the introduction of the vibrating fixture in the vibratory finishing setup as compared to the conventional vibratory finishing setup wherein the fixture is not vibrating. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=laser%20shock%20peening" title="laser shock peening">laser shock peening</a>, <a href="https://publications.waset.org/abstracts/search?q=material%20removal" title=" material removal"> material removal</a>, <a href="https://publications.waset.org/abstracts/search?q=surface%20roughness" title=" surface roughness"> surface roughness</a>, <a href="https://publications.waset.org/abstracts/search?q=vibrating%20fixture" title=" vibrating fixture"> vibrating fixture</a>, <a href="https://publications.waset.org/abstracts/search?q=vibratory%20finishing" title=" vibratory finishing"> vibratory finishing</a> </p> <a href="https://publications.waset.org/abstracts/78478/enhancement-of-material-removal-rate-of-complex-featured-surfaces-in-vibratory-finishing" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/78478.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">222</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">954</span> Forced Vibration of an Auxetic Cylindrical Shell Containing Fluid Under the Influence of Shock Load</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Korosh%20Khorshidi">Korosh Khorshidi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Due to the increasing use of different materials, such as auxetic structures, it is necessary to investigate mechanical phenomena, such as vibration, in structures made of these types of materials. This paper examines the forced vibrations of a three-layer cylindrical shell containing inviscid fluid under shock load. All three layers are made of aluminum, and the central layer is made of a re-entrant honeycomb cell structure. Using high-order shear deformation theories (HSDT) and Hamilton’s principle, the governing equations of the system have been extracted and solved by the Galerkin weighted residual method. The outputs of the Abaqus finite element software are used to validate the results. The system is investigated with both simple and clamped support conditions. Finally, this study investigates the influence of the geometrical parameters of the shell and the auxetic structure, as well as the type, intensity, duration, and location of the load, and the effect of the fluid on the dynamic and time responses. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=force%20vibration" title="force vibration">force vibration</a>, <a href="https://publications.waset.org/abstracts/search?q=cylindrical%20shell" title=" cylindrical shell"> cylindrical shell</a>, <a href="https://publications.waset.org/abstracts/search?q=auxetic%20structure" title=" auxetic structure"> auxetic structure</a>, <a href="https://publications.waset.org/abstracts/search?q=inviscid%20fluid" title=" inviscid fluid"> inviscid fluid</a> </p> <a href="https://publications.waset.org/abstracts/184704/forced-vibration-of-an-auxetic-cylindrical-shell-containing-fluid-under-the-influence-of-shock-load" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/184704.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">43</span> </span> </div> </div> <ul class="pagination"> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=dengue%20shock%20syndrome%20%28DSS%29&page=9" rel="prev">&lsaquo;</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=dengue%20shock%20syndrome%20%28DSS%29&page=1">1</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=dengue%20shock%20syndrome%20%28DSS%29&page=2">2</a></li> <li class="page-item disabled"><span class="page-link">...</span></li> <li class="page-item"><a class="page-link" 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