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635</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: pulmonary dysfunction</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">635</span> NO2 Exposure Effect on the Occurrence of Pulmonary Dysfunction the Police Traffic in Jakarta</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Bambang%20Wispriyono">Bambang Wispriyono</a>, <a href="https://publications.waset.org/abstracts/search?q=Satria%20Pratama"> Satria Pratama</a>, <a href="https://publications.waset.org/abstracts/search?q=Haryoto%20Kusnoputranto"> Haryoto Kusnoputranto</a>, <a href="https://publications.waset.org/abstracts/search?q=Faisal%20Yunus"> Faisal Yunus</a>, <a href="https://publications.waset.org/abstracts/search?q=Meliana%20Sari"> Meliana Sari</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction/objective: The impact of the development of motor vehicles is increasing the number of pollutants in the air. One of the substances that cause serious health problems is NO2. The health impacts arising from exposure to NO2 include pulmonary function impairment. The purpose of this study was to determine the relationship of NO2 exposure on the incidence of pulmonary function impairment. Methods: We are using a cross-sectional study design with 110 traffic police who were divided into two groups: exposed (police officers working on the highway) and the unexposed group (police officers working in the office). Election subject convenient sampling carried out in each group to the minimum number of samples met. Results: The results showed that the average NO2 in the exposed group was 18.72 ppb and unexposed group is 4.14 ppb. Pulmonary dysfunction on exposed and unexposed groups showed that FVC (Forced Vital Capacity) value are 88.68 and 90.27. And FEV1 (Forced Expiratory Volume in One) value are 94.9 and 95.16. Some variables like waist circumference, Body Mass Index, Visceral Fat, and Fat has associated with the incidence of Pulmonary Dysfunction (p < 0.05). Conclusion: Health monitoring is needed to decreasing health risk in Policeman. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=NO2" title="NO2">NO2</a>, <a href="https://publications.waset.org/abstracts/search?q=pulmonary%20dysfunction" title=" pulmonary dysfunction"> pulmonary dysfunction</a>, <a href="https://publications.waset.org/abstracts/search?q=police%20traffic" title=" police traffic"> police traffic</a>, <a href="https://publications.waset.org/abstracts/search?q=Jakarta" title=" Jakarta"> Jakarta</a> </p> <a href="https://publications.waset.org/abstracts/62743/no2-exposure-effect-on-the-occurrence-of-pulmonary-dysfunction-the-police-traffic-in-jakarta" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/62743.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">255</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">634</span> A Theoretical to Conceptual Paper: The Use of Phosphodiesterase Inhibitors, Endothelin Receptor Antagonists and/or Prostacyclin Analogs in Acute Pulmonary Embolism</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ryan%20M.%20Monti">Ryan M. Monti</a>, <a href="https://publications.waset.org/abstracts/search?q=Bijal%20Mehta"> Bijal Mehta</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In cases of massive pulmonary embolism, defined as acute pulmonary embolism presenting with systemic hypotension or right ventricular dysfunction and impending failure, there is indication that unconventional therapies, such as phosphodiesterase inhibitors, endothelin receptor antagonists, and/or prostacyclin analogs may decrease the morbidity and mortality. Based on the premise that dilating the pulmonary artery will decrease the pulmonary vascular pressure, while simultaneously decreasing the aggregation of platelets, it can be hypothesized that increased blood flow through the pulmonary artery will decrease right heart strain and subsequent morbidity and mortality. While this theory has yet to be formally studied, the recommendations for treating massive pulmonary embolism with phosphodiesterase inhibitors, endothelin receptor antagonists, and/or prostacyclin analogs in conjunction with the current standards of care in massive pulmonary embolism should be formally studied. In particular, patients with massive PE who are unable to undergo thrombolysis/surgical intervention may be the ideal population to study the use of these treatments to determine any decrease in mortality and morbidity (short term and long term). <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=acute%20pulmonary%20thromboembolism" title="acute pulmonary thromboembolism">acute pulmonary thromboembolism</a>, <a href="https://publications.waset.org/abstracts/search?q=treatment%20of%20pulmonary%20embolism" title=" treatment of pulmonary embolism"> treatment of pulmonary embolism</a>, <a href="https://publications.waset.org/abstracts/search?q=use%20of%20phosphodiesterase%20inhibitors" title=" use of phosphodiesterase inhibitors"> use of phosphodiesterase inhibitors</a>, <a href="https://publications.waset.org/abstracts/search?q=endothelin%20receptor%20antagonists" title=" endothelin receptor antagonists"> endothelin receptor antagonists</a>, <a href="https://publications.waset.org/abstracts/search?q=prostacyclin%20analogs%20in%20PE" title=" prostacyclin analogs in PE"> prostacyclin analogs in PE</a> </p> <a href="https://publications.waset.org/abstracts/49295/a-theoretical-to-conceptual-paper-the-use-of-phosphodiesterase-inhibitors-endothelin-receptor-antagonists-andor-prostacyclin-analogs-in-acute-pulmonary-embolism" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/49295.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">225</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">633</span> An Increase in Glucose Uptake per se is Insufficient to Induce Oxidative Stress and Vascular Endothelial Cell Dysfunction</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Heba%20Khader">Heba Khader</a>, <a href="https://publications.waset.org/abstracts/search?q=Victor%20Solodushko"> Victor Solodushko</a>, <a href="https://publications.waset.org/abstracts/search?q=Brian%20Fouty"> Brian Fouty</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Hyperglycemia is a hallmark of uncontrolled diabetes and causes vascular endothelial dysfunction. An increase in glucose uptake and metabolism by vascular endothelial cells is the presumed trigger for this hyperglycemia-induced dysfunction. Glucose uptake into vascular endothelial cells is mediated largely by Glut-1. Glut-1 is an equilibrative glucose transporter with a Km value of 2 mM. At physiologic glucose concentrations, Glut-1 is almost saturated and, therefore, increasing glucose concentration does not increase glucose uptake unless Glut-1 is upregulated. However, hyperglycemia downregulates Glut-1 and decreases rather than increases glucose uptake in vascular endothelial cells. This apparent discrepancy necessitates further study on the effect of increasing glucose uptake on the oxidative state and function of vascular endothelial cells. To test this, a Tet-on system was generated to conditionally regulate Glut-1 expression in endothelial cells by the addition and removal of doxycycline. Glut-1 overexpression was confirmed by Western blot and radiolabeled glucose uptake measurements. Upregulation of Glut-1 resulted in a 4-fold increase in glucose uptake into endothelial cells as determined by 3H deoxy-D-glucose uptake. Increased glucose uptake through Glut-1 did not induce an oxidative stress nor did it cause endothelial dysfunction in rat pulmonary microvascular endothelial cells determined by monolayer resistance, cell proliferation or advanced glycation end product formation. Increased glucose uptake through Glut-1did not lead to an increase in glucose metabolism, due in part to inhibition of hexokinase in Glut-1 overexpressing cells. In summary, this study demonstrates that increasing glucose uptake and intracellular glucose by overexpression of Glut-1 does not alter the oxidative state of rat pulmonary microvascular endothelial cells or cause endothelial cell dysfunction. These results conflict with the current paradigm that hyperglycemia leads to oxidative stress and endothelial dysfunction in vascular endothelial cells through an increase in glucose uptake. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=endothelial%20cells" title="endothelial cells">endothelial cells</a>, <a href="https://publications.waset.org/abstracts/search?q=glucose%20uptake" title=" glucose uptake"> glucose uptake</a>, <a href="https://publications.waset.org/abstracts/search?q=Glut1" title=" Glut1"> Glut1</a>, <a href="https://publications.waset.org/abstracts/search?q=hyperglycemia" title=" hyperglycemia"> hyperglycemia</a> </p> <a href="https://publications.waset.org/abstracts/40571/an-increase-in-glucose-uptake-per-se-is-insufficient-to-induce-oxidative-stress-and-vascular-endothelial-cell-dysfunction" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/40571.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">340</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">632</span> A Case of Postpartum Pulmonary Edema Induced by Oxytocin</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=May%20Zaw">May Zaw</a>, <a href="https://publications.waset.org/abstracts/search?q=Amber%20Latif"> Amber Latif</a>, <a href="https://publications.waset.org/abstracts/search?q=William%20Lim"> William Lim</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Postpartum dyspnea can be due to many causes, such as pulmonary embolism, amniotic fluid embolism, and peripartum cardiomyopathy, but less frequently due to acute pulmonary edema. The incidence of acute pulmonary edema during pregnancy and in the postpartum period has been estimated to be around 0.08%. About half of the cases are attributed to tocolytic therapy. Herein, we present a case of a young woman presenting with acute hypoxia after induction of labor with oxytocin and found to have acute pulmonary edema. This case aims to illustrate and add to a growing body of literature regarding oxytocin-induced acute pulmonary edema and highlights the importance of recognizing the rare complication of oxytocin and necessary interventions to avoid complications. Oxytocin-induced pulmonary edema is a relatively uncommon condition, but physicians should have a high index of suspicion to initiate timely intervention and avoid fetal complications. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=pulmonary" title="pulmonary">pulmonary</a>, <a href="https://publications.waset.org/abstracts/search?q=pregnancy" title=" pregnancy"> pregnancy</a>, <a href="https://publications.waset.org/abstracts/search?q=oxytocin" title=" oxytocin"> oxytocin</a>, <a href="https://publications.waset.org/abstracts/search?q=postpartum" title=" postpartum"> postpartum</a> </p> <a href="https://publications.waset.org/abstracts/153892/a-case-of-postpartum-pulmonary-edema-induced-by-oxytocin" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/153892.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">90</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">631</span> Association of Airborne Emissions with Pulmonary Dysfunction, XRCC1 Gene Polymorphism, and Some Inflammatory Markers in Aluminum Workers</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Gehan%20Moubarz">Gehan Moubarz</a>, <a href="https://publications.waset.org/abstracts/search?q=Atef%20M.%20F.%20Mohammed"> Atef M. F. Mohammed</a>, <a href="https://publications.waset.org/abstracts/search?q=Inas%20A.%20Saleh"> Inas A. Saleh</a>, <a href="https://publications.waset.org/abstracts/search?q=Heba%20Mahdy-Abdallah"> Heba Mahdy-Abdallah</a>, <a href="https://publications.waset.org/abstracts/search?q=Amal%20Saad-Hussein"> Amal Saad-Hussein</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This study estimates the association between respiratory outcomes among employees of a secondary aluminum plant and airborne pollutants. Additionally, it looks into the relationship between pulmonary dysfunction in workers and XRCC1 gene polymorphisms. 110 exposed workers and 58 non-exposed workers participated in the study. Measurements have been conducted on SO₂, NO₂, and particulate particles. Pulmonary function was tested. Eosinophil cationic protein (ECP), C-reactive protein (CRP), matrix metalloproteinase-1 (MMP-1), interleukin 6 (IL6), GM-CSF, X-Ray Repair Cross Complementing 1 (XRCC1) protein, and genotyping of XRCC1 gene polymorphisms were examined. Results: The annual average concentrations of (PM₂.₅, PM₁₀, TSP, SO₂, and NO₂) were lower than the permissible limit. The areas around ovens, evaporators, and cold rolling mills exhibited the highest amounts. The majority of employees in these departments had impaired lung function. With longer exposure times, the exposed group's FEV1% and FVC% considerably reduced. The exposed workers had considerably higher XRCC1 levels. The evaluated inflammatory biomarkers showed no statistically significant difference. Conclusion: Aluminum workers are at risk of developing respiratory disorders. The level of serum XRCC1 may act as a biomarker that might be very useful for detecting susceptible workers. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=aluminum%20industry" title="aluminum industry">aluminum industry</a>, <a href="https://publications.waset.org/abstracts/search?q=particulate%20matter" title=" particulate matter"> particulate matter</a>, <a href="https://publications.waset.org/abstracts/search?q=SO%E2%82%82" title=" SO₂"> SO₂</a>, <a href="https://publications.waset.org/abstracts/search?q=NO%E2%82%82" title=" NO₂"> NO₂</a>, <a href="https://publications.waset.org/abstracts/search?q=lung%20function" title=" lung function"> lung function</a>, <a href="https://publications.waset.org/abstracts/search?q=XRCC1%20gene%20polymorphism" title=" XRCC1 gene polymorphism"> XRCC1 gene polymorphism</a>, <a href="https://publications.waset.org/abstracts/search?q=XRCC1%20protein" title=" XRCC1 protein"> XRCC1 protein</a>, <a href="https://publications.waset.org/abstracts/search?q=inflammatory%20biomarkers" title=" inflammatory biomarkers"> inflammatory biomarkers</a> </p> <a href="https://publications.waset.org/abstracts/193901/association-of-airborne-emissions-with-pulmonary-dysfunction-xrcc1-gene-polymorphism-and-some-inflammatory-markers-in-aluminum-workers" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/193901.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">10</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">630</span> Strategies For Management Of Massive Intraoperative Airway Haemorrhage Complicating Surgical Pulmonary Embolectomy</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nicholas%20Bayfield">Nicholas Bayfield</a>, <a href="https://publications.waset.org/abstracts/search?q=Liam%20Bibo"> Liam Bibo</a>, <a href="https://publications.waset.org/abstracts/search?q=Kaushelandra%20Rathore"> Kaushelandra Rathore</a>, <a href="https://publications.waset.org/abstracts/search?q=Lucas%20Sanders"> Lucas Sanders</a>, <a href="https://publications.waset.org/abstracts/search?q=Mark%20Newman"> Mark Newman</a> </p> <p class="card-text"><strong>Abstract:</strong></p> INTRODUCTION: Surgical pulmonary embolectomy is an established therapy for acute pulmonary embolism causing right heart dysfunction and haemodynamic instability. Massive intraoperative airway haemorrhage is a rare complication of pulmonary embolectomy. We present our institutional experience with massive airway haemorrhage complicating pulmonary embolectomy and discuss optimal therapeutic strategies. METHODS: A retrospective review of emergent surgical pulmonary embolectomy patients was undertaken. Cases complicated by massive intra-operative airway haemorrhage were identified. Intra- and peri-operative management strategies were analysed and discussed. RESULTS: Of 76 patients undergoing emergent or salvage pulmonary embolectomy, three cases (3.9%) of massive intraoperative airway haemorrhage were identified. Haemorrhage always began on weaning from cardiopulmonary bypass. Successful management strategies involved intraoperative isolation of the side of bleeding, occluding the affected airway with an endobronchial blocker, institution of veno-arterial (VA) extracorporeal membrane oxygenation (ECMO) and reversal of anticoagulation. Running the ECMO without heparinisation allows coagulation to occur. Airway haemorrhage was controlled within 24 hours of operation in all patients, allowing re-institution of dual lung ventilation and decannulation from ECMO. One case in which positive end-expiratory airway pressure was trialled initially was complicated by air embolism. Although airway haemorrhage was controlled successfully in all cases, all patients died in-hospital for reasons unrelated to the airway haemorrhage. CONCLUSION: Massive intraoperative airway haemorrhage during pulmonary embolectomy is a rare complication with potentially catastrophic outcomes. Re-perfusion alveolar and capillary injury is the likely aetiology. With a systematic approach to management, airway haemorrhage can be well controlled intra-operatively and often resolves within 24 hours. Stopping blood flow to the pulmonary arteries and support of oxygenation by the institution of VA ECMO is important. This management has been successful in our 3 cases. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=pulmonary%20embolectomy" title="pulmonary embolectomy">pulmonary embolectomy</a>, <a href="https://publications.waset.org/abstracts/search?q=cardiopulmonary%20bypass" title=" cardiopulmonary bypass"> cardiopulmonary bypass</a>, <a href="https://publications.waset.org/abstracts/search?q=cardiac%20surgery" title=" cardiac surgery"> cardiac surgery</a>, <a href="https://publications.waset.org/abstracts/search?q=pulmonary%20embolism" title=" pulmonary embolism"> pulmonary embolism</a> </p> <a href="https://publications.waset.org/abstracts/142008/strategies-for-management-of-massive-intraoperative-airway-haemorrhage-complicating-surgical-pulmonary-embolectomy" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/142008.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">175</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">629</span> A Prospective Randomised Observational Study of Obstructed Total Anamalous Pulmonary Venous Connection (TAPVC) Repair Patients</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sanjeev%20Singh">Sanjeev Singh</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Obstructed total anomalous pulmonary venous connection (OTAPVC) typically presents with severe cardiovascular decompensation and requires urgent surgical management. Pulmonary arterial hypertension (PAH) is a major risk factor affecting mortality. Perioperative management focuses on providing inotropic support and managing potential pulmonary hypertensive episodes. The aim of this study was to determine the outcome of patients with high pulmonary arterial pressure (PAP) with milrinone alone and a combination of milrinone and inhaled nitric oxide (INO). Material and Methods: After the approval of the ethical committee, this single-center prospective randomized and observational study was conducted over a period of two years among eighty-six patients with obstructed TAPVC repair with severe PAH. Group-I patients received milrinone, and Group-II patients received both milrinone (after aortic cross-clamp removal) and INO during the post-operative period at the cardiac care unit (CCU). Clinical outcomes such as ventilation time, length of stay (LOS) in the CCU, LOS in the hospital, complications, and hospital mortality were compared between the two groups. Result: The average ventilation time, LOS in CCU, and LOS in hospital for group I were 96.82 ± 19.46 hours, 10.91 ± 7.53 days, and 14.46 ± 7.58 days, respectively, and for group II, it was 85.14 ± 15.79 hours, 7.28 ± 3.68 days, and 10.21 ± 3.14 days, respectively, which was statistically significantly lower for group II. Reintubation, RV dysfunction, and hospital mortality were 16.3%, 37.2%, and 6.9% in group I, and 4.8%, 14.6%, and 2.4% in group II, respectively. The P value for each variable was significant < 0.05 (except mortality). Conclusion: Preoperative obstruction is a risk factor for postoperative obstruction, as 235 patients with obstructed TAPVC had severe PAH (39.98%) in this study. Management of severe PAH with a combination of milrinone and INO had a better outcome than milrinone alone. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=inhaled%20nitric%20oxide" title="inhaled nitric oxide">inhaled nitric oxide</a>, <a href="https://publications.waset.org/abstracts/search?q=milrinone" title=" milrinone"> milrinone</a>, <a href="https://publications.waset.org/abstracts/search?q=pulmonary%20artery%20hypertension" title=" pulmonary artery hypertension"> pulmonary artery hypertension</a>, <a href="https://publications.waset.org/abstracts/search?q=total%20anomalous%20pulmonary%20venous%20connection" title=" total anomalous pulmonary venous connection"> total anomalous pulmonary venous connection</a> </p> <a href="https://publications.waset.org/abstracts/191851/a-prospective-randomised-observational-study-of-obstructed-total-anamalous-pulmonary-venous-connection-tapvc-repair-patients" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/191851.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">21</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">628</span> Pulmonary Valve Papillary Fibroelastoma: A Case Report of a Fibroelastoma Presenting as a Pulmonary Embolism</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Frazer%20Kirk">Frazer Kirk</a>, <a href="https://publications.waset.org/abstracts/search?q=Matthew%20Yong"> Matthew Yong</a>, <a href="https://publications.waset.org/abstracts/search?q=Peter%20Williams"> Peter Williams</a>, <a href="https://publications.waset.org/abstracts/search?q=Andrie%20Strobel"> Andrie Strobel</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Pulmonary valve papillary fibroelastoma is an exceedingly rare pathology. The experience and literature regarding them are largely anecdotal and based on sporadic, single case reports. Throughout their known history, two features remain salient that they are classically asymptomatic and found incidentally. The demographic profile of those affected is unclear, as reports regarding those affected are mixed, and there is no clear gender or age predominance, although there is some suggestion of a predisposition to affect females. Nor has there been a well-structured epidemiological study of the entity. Interestingly they are becoming more common on peri-mortum examination. Here-after we describe our experience with a symptomatic presentation of pulmonary papillary fibroelastoma masquerading as a pulmonary embolism and its subsequent assessment and management, with intraoperative photography and echocardiography for reference. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cardiac%20tumor" title="cardiac tumor">cardiac tumor</a>, <a href="https://publications.waset.org/abstracts/search?q=pulmonary%20valve" title=" pulmonary valve"> pulmonary valve</a>, <a href="https://publications.waset.org/abstracts/search?q=fibroelastoma" title=" fibroelastoma"> fibroelastoma</a>, <a href="https://publications.waset.org/abstracts/search?q=cardiac%20surgery" title=" cardiac surgery"> cardiac surgery</a> </p> <a href="https://publications.waset.org/abstracts/142247/pulmonary-valve-papillary-fibroelastoma-a-case-report-of-a-fibroelastoma-presenting-as-a-pulmonary-embolism" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/142247.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">219</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">627</span> Impact of Pulmonary Rehabilitation on Respiratory Parameters in Interstitial Lung Disease Patients: A Tertiary Care Hospital Study</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Vivek%20Ku">Vivek Ku</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20K.%20Janmeja"> A. K. Janmeja</a>, <a href="https://publications.waset.org/abstracts/search?q=D.%20Aggarwal"> D. Aggarwal</a>, <a href="https://publications.waset.org/abstracts/search?q=R.%20Gupta"> R. Gupta</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Purpose: Pulmonary rehabilitation plays a key role in management of chronic lung diseases. However, pulmonary rehabilitation is an underused modality in the management of interstitial lung disease (ILD). This is because limited information is available in literature and no data is available from India on this issue so far. The study was carried out to evaluate the role of pulmonary rehabilitation on respiratory parameters in ILD patients. Methods: The present study was a prospective randomized non-blind case control study. Total of 40 ILD patients were randomized into 2 groups of 20 patients each viz ‘pulmonary rehabilitation group’ and ‘control group’. Pulmonary rehabilitation group underwent 8 weeks pulmonary rehabilitation (PR) along with medical management as per guidelines and the control group was advised only medical management. Results: Mean age in case group was 59.15 ± 10.39 years and in control group was 62.10 ± 14.54 years. The case and the control groups were matched for age and sex. Mean MRC grading at the end of 8 weeks showed significant improvement in the case group as compared to control group (p= 0.011 vs p = 0.655). Similarly, mean St. George Respiratory Questionnaire (SGRQ) score also showed significant improvement in pulmonary rehabilitation group at the end of the study (p= 0.001 vs p= 0.492). However, FEV1 and FVC had no significant change in the case and control group. Similarly, blood gases also did not show any significant difference in the group. Conclusion: Pulmonary rehabilitation improves breathlessness and thereby improves quality of life in the patients suffering from ILD. However, the pulmonary function values and blood gases are unaffected by pulmonary rehabilitation. Clinical Implications: Further large scale multicentre study is needed to ascertain the association. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=ILD" title="ILD">ILD</a>, <a href="https://publications.waset.org/abstracts/search?q=pulmonary%20rehabilitation" title=" pulmonary rehabilitation"> pulmonary rehabilitation</a>, <a href="https://publications.waset.org/abstracts/search?q=quality%20of%20life" title=" quality of life"> quality of life</a>, <a href="https://publications.waset.org/abstracts/search?q=pulmonary%20functions" title=" pulmonary functions"> pulmonary functions</a> </p> <a href="https://publications.waset.org/abstracts/39543/impact-of-pulmonary-rehabilitation-on-respiratory-parameters-in-interstitial-lung-disease-patients-a-tertiary-care-hospital-study" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/39543.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">270</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">626</span> Predicting Marital Burnout Based on Irrational Beliefs and Sexual Dysfunction of Couples</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Elnaz%20Bandeh">Elnaz Bandeh</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This study aimed to predict marital burnout based on irrational beliefs and sexual dysfunction of couples. The research method was descriptive-correlational, and the statistical population included all couples who consulted to counseling clinics in the fall of 2016. The sample consisted of 200 people who were selected by convenience sampling and answered the Ahwaz Irrational Beliefs Questionnaire, Pines Couple Burnout, and Hudson Marital Satisfaction Questionnaire. The data were analyzed using regression coefficient. The results of regression analysis showed that there was a linear relationship between irrational beliefs and couple burnout and dimensions of helplessness toward change, expectation of approval from others, and emotional irresponsibility were positive and significant predictors of couple burnout. However, after avoiding the problem of power, it was not a significant predictor of marital dissatisfaction. There was also a linear relationship between sexual dysfunction and couple burnout, and sexual dysfunction was a positive and significant predictor of couple burnout. Based on the findings, it can be concluded that irrational beliefs and sexual dysfunction play a role in couple dysfunction. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=couple%20burnout" title="couple burnout">couple burnout</a>, <a href="https://publications.waset.org/abstracts/search?q=irrational%20beliefs" title=" irrational beliefs"> irrational beliefs</a>, <a href="https://publications.waset.org/abstracts/search?q=sexual%20dysfunction" title=" sexual dysfunction"> sexual dysfunction</a>, <a href="https://publications.waset.org/abstracts/search?q=marital%20relationship" title=" marital relationship"> marital relationship</a> </p> <a href="https://publications.waset.org/abstracts/119800/predicting-marital-burnout-based-on-irrational-beliefs-and-sexual-dysfunction-of-couples" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/119800.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">155</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">625</span> The Role of Pulmonary Resection in Complicated Primary Pediatric Pulmonary Tuberculosis: An Evidence-Based Case Report</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Hendra%20Wibowo">Hendra Wibowo</a>, <a href="https://publications.waset.org/abstracts/search?q=Suprayitno%20Wardoyo"> Suprayitno Wardoyo</a>, <a href="https://publications.waset.org/abstracts/search?q=Dhama%20Shinta"> Dhama Shinta</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: Pediatric pulmonary tuberculosis (TB) incidence was increasing, with many undetected cases. In complicated TB, treatment should consist of returning pulmonary function, preventing further complications, and eliminating bacteria. Complicated TB management was still controversial, and surgery was one of the treatments that should be evaluated in accordance with its role in the treatment of complicated TB. Method: This study was an evidence-based case report. The database used for the literature search were Cochrane, Medline, Proquest, and ScienceDirect. Keywords for the search were ‘primary pulmonary tuberculosis’, ‘surgery’, ‘lung resection’, and ‘children’. Inclusion criteria were studies in English or Indonesian, with children under 18 years old as subject, and full-text articles available. The assessment was done according to Oxford Centre for evidence-based medicine 2011. Results: Six cohort studies were analyzed. Surgery was indicated for patients with complicated TB that were unresponsive towards treatment. It should be noted that the experiments were done before the standard WHO antituberculosis therapy was applied; thus, the result may be different from the current application. Conclusion: Currently, there was no guideline on pulmonary resection. However, surgery yielded better mortality and morbidity in children with complicated pulmonary TB. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=pediatric" title="pediatric">pediatric</a>, <a href="https://publications.waset.org/abstracts/search?q=pulmonary" title=" pulmonary"> pulmonary</a>, <a href="https://publications.waset.org/abstracts/search?q=surgery" title=" surgery"> surgery</a>, <a href="https://publications.waset.org/abstracts/search?q=therapy" title=" therapy"> therapy</a>, <a href="https://publications.waset.org/abstracts/search?q=tuberculosis" title=" tuberculosis"> tuberculosis</a> </p> <a href="https://publications.waset.org/abstracts/108284/the-role-of-pulmonary-resection-in-complicated-primary-pediatric-pulmonary-tuberculosis-an-evidence-based-case-report" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/108284.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">106</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">624</span> Effect of Inspiratory Muscle Training on Diaphragmatic Strength Following Coronary Revascularization</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Abeer%20Ahmed%20Abdelhamed"> Abeer Ahmed Abdelhamed</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: Postoperative pulmonary complications (PPCs) are the most common complications observed and managed after abdominal or cardiothoracic surgery. Hypoxemia, atelectasis, pleural effusion, or diaphragmatic dysfunction, are often a source of morbidity in cardiac surgery patients, and are more common in patients receiving unilateral or bilateral internal mammary artery (IMT) grafts than patients receiving saphenous vein (SV) grafts alone. Purpose: The aim of this work was to investigate the effect of Threshold load inspiratory muscle training on pulmonary gas exchange and maximum inspiratory pressure (MIP) in patient undergoing coronary revascularization. Subject: Thirty three male patients eligible for coronary revascularization were selected to participate in the study. Method: They were divided into two groups(17 patients in the intervention group and 16 patients in the control group), the interventional group received inspiratory muscle training at 30% of their maximum inspiratory pressure throughout the hospitalization period in addition to routine post operative care. Result: The results of this study showed a significant improvement on maximum inspiratory pressure(MIP), Arterial-alveolar pressure gradient (A-a gradient) and oxygen saturation in the intervention group. Conclusion: Inspiratory muscle training using threshold mode significantly improves maximum inspiratory pressure, pulmonary gas exchange tested by alveolar-arterial gradient and oxygen saturation in Patients undergoing coronary revascularization. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=coronary%20revascularization" title="coronary revascularization">coronary revascularization</a>, <a href="https://publications.waset.org/abstracts/search?q=inspiratory%20muscle%20training" title=" inspiratory muscle training"> inspiratory muscle training</a>, <a href="https://publications.waset.org/abstracts/search?q=maximum%20inspiratory%20pressure" title=" maximum inspiratory pressure"> maximum inspiratory pressure</a>, <a href="https://publications.waset.org/abstracts/search?q=pulmonary%20gas%20exchange" title=" pulmonary gas exchange"> pulmonary gas exchange</a> </p> <a href="https://publications.waset.org/abstracts/31159/effect-of-inspiratory-muscle-training-on-diaphragmatic-strength-following-coronary-revascularization" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/31159.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">300</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">623</span> CT-Scan Transition of Pulmonary Edema Due to Water-Soluble Paint Inhalation</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Masashi%20Kanazawa">Masashi Kanazawa</a>, <a href="https://publications.waset.org/abstracts/search?q=Takaaki%20Nakano"> Takaaki Nakano</a>, <a href="https://publications.waset.org/abstracts/search?q=Masaaki%20Takemoto"> Masaaki Takemoto</a>, <a href="https://publications.waset.org/abstracts/search?q=Tomonori%20Imamura"> Tomonori Imamura</a>, <a href="https://publications.waset.org/abstracts/search?q=Mamiko%20Sugimura"> Mamiko Sugimura</a>, <a href="https://publications.waset.org/abstracts/search?q=Toshitaka%20Ito"> Toshitaka Ito</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: We experienced a massive disaster due to inhalation of water-soluble paint. Sixteen patients were brought to our emergency room, and pulmonary edema was revealed on the CT images of 12 cases. Purpose: Transition of chest CT-scan findings in cases with pulmonary edema was examined. Method: CT-scans were performed on the 1st, 2nd, 5th, and 19th days after the inhalation event. Patients whose pulmonary edema showed amelioration or exacerbation were classified into the improvement or the exacerbation group, respectively. Those with lung edema findings appearing at different sites after the second day were classified into the changing group. Results: Eight, one and three patients were in the improvement, exacerbation and changing groups, respectively. In all cases, the pulmonary edema had disappeared from CT images on the 19th day after the inhalation event. Conclusion: Inhalation of water-soluble paints is considered to be relatively safe. However, our observations in these emergency cases suggest that, even if pulmonary edema is not severe immediately after the exposure, new lesions may appear later and existing lesions may worsen. Follow-up imaging is thus necessary for about two weeks. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=CT%20scan" title="CT scan">CT scan</a>, <a href="https://publications.waset.org/abstracts/search?q=intoxication" title=" intoxication"> intoxication</a>, <a href="https://publications.waset.org/abstracts/search?q=pulmonary%20edema" title=" pulmonary edema"> pulmonary edema</a>, <a href="https://publications.waset.org/abstracts/search?q=water-soluble%20paint" title=" water-soluble paint"> water-soluble paint</a> </p> <a href="https://publications.waset.org/abstracts/74622/ct-scan-transition-of-pulmonary-edema-due-to-water-soluble-paint-inhalation" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/74622.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">173</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">622</span> Validation Pulmonary Embolus Severity Index Score Early Mortality Rate at 1, 3, 7 Days in Patients with a Diagnosis of Pulmonary Embolism</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nicholas%20Marinus%20Batt">Nicholas Marinus Batt</a>, <a href="https://publications.waset.org/abstracts/search?q=Angus%20Radford"> Angus Radford</a>, <a href="https://publications.waset.org/abstracts/search?q=Khaled%20Saraya"> Khaled Saraya</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Pulmonary Embolus Severity Index (PESI) score is a well-validated decision-making score grading mortality rates (MR) in patients with a suspected or confirmed diagnosis of pulmonary embolism (PE) into 5 classes. Thirty and 90 days MR in class I and II are lower allowing the treatment of these patients as outpatients. In a London District General Hospital (DGH) with mixed ethnicity and high disease burden, we looked at MR at 1, 3, and 7 days of all PESI score classes. Our pilot study of 112 patients showed MR of 0% in class I, II, and III. The current study includes positive Computed Tomographic Scans (CT scans) for PE over the following three years (total of 555). MR was calculated for all PESI score classes at 1, 3 & 7 days. Thirty days MR was additionally calculated to validate the study. Our initial results so far are in line with our pilot studies. Further subgroup analysis accounting for the local co-morbidities and disease burden and its impact on the MR will be undertaken. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Pulmonary%20Embolism%20%28PE%29" title="Pulmonary Embolism (PE)">Pulmonary Embolism (PE)</a>, <a href="https://publications.waset.org/abstracts/search?q=Pulmonary%20Embolism%20Severity%20Index%20%28PESI%29%20score" title=" Pulmonary Embolism Severity Index (PESI) score"> Pulmonary Embolism Severity Index (PESI) score</a>, <a href="https://publications.waset.org/abstracts/search?q=mortality%20rate%20%28MR%29" title=" mortality rate (MR)"> mortality rate (MR)</a>, <a href="https://publications.waset.org/abstracts/search?q=CT%20pulmonary%20artery" title=" CT pulmonary artery"> CT pulmonary artery</a> </p> <a href="https://publications.waset.org/abstracts/69902/validation-pulmonary-embolus-severity-index-score-early-mortality-rate-at-1-3-7-days-in-patients-with-a-diagnosis-of-pulmonary-embolism" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/69902.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">264</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">621</span> Qualitative and Quantitative Assessment of Sexual Dysfunction in Primary Obesity through an Observational Study</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Aravind%20Bagade%20Shankaranarayana">Aravind Bagade Shankaranarayana</a>, <a href="https://publications.waset.org/abstracts/search?q=Parampalli%20Geetha"> Parampalli Geetha</a>, <a href="https://publications.waset.org/abstracts/search?q=Pallavi%20Gupta"> Pallavi Gupta</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Objective: This study intends to evaluate sexual dysfunction qualitatively and quantitatively in males suffering from primary obesity through a single centered, observational study. Design and Methods: Sexual function of 33 obese males from the outpatient department of the hospital was assessed using IIEF questionnaire and semen analysis and the results were assessed for statistical significance. Results: A varying degree of sexual dysfunction was observed in four out of five areas of sexual functioning viz. erectile function (p<0.02), orgasmic function (p<0.02), sexual desire (p<0.08) and overall satisfaction (p<0.000) in obese individuals. Statistically significant dysfunction was not observed in intercourse satisfaction. Semen analysis was normal in 19 individuals (63.3%) and abnormal in 11 individuals (36.7%), with statistically insignificant p value 0.144, suggesting mild to moderate variation in semen parameters. Conclusions: Varying degree of sexual dysfunction is present in obese males, suggesting that obesity has a possible role in reducing the quality of sexual functioning in males as indicated in the classical Ayurvedic literature. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=erectile%20dysfunction" title="erectile dysfunction">erectile dysfunction</a>, <a href="https://publications.waset.org/abstracts/search?q=krucchra%20vyavaya" title=" krucchra vyavaya"> krucchra vyavaya</a>, <a href="https://publications.waset.org/abstracts/search?q=obesity" title=" obesity"> obesity</a>, <a href="https://publications.waset.org/abstracts/search?q=sthoulya" title=" sthoulya"> sthoulya</a> </p> <a href="https://publications.waset.org/abstracts/8714/qualitative-and-quantitative-assessment-of-sexual-dysfunction-in-primary-obesity-through-an-observational-study" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/8714.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">329</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">620</span> Capture-recapture to Estimate Completeness of Pulmonary Tuberculosis with Two Sources</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ratchadaporn%20Ungcharoen">Ratchadaporn Ungcharoen</a>, <a href="https://publications.waset.org/abstracts/search?q=Lily%20Ingsrisawang"> Lily Ingsrisawang</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Capture-recapture methods are popular techniques for indirect estimation the size of wildlife populations and the completeness of cases in epidemiology and social sciences. The aim of this study was to estimate the completeness of pulmonary tuberculosis cases confirmed by two sources of hospital registrations and surveillance systems in 2013 in Nakhon Pathom province, Thailand. Several estimators of population size were considered: the Lincoln-Petersen estimator, the Chapman estimator, the Chao’s lower bound estimator, the Zelterman’s estimator, etc. We focus on the Chapman and Chao’s lower bound estimators for estimating the completeness of pulmonary tuberculosis from two sources. The retrieved pulmonary tuberculosis data from two sources were analyzed and bootstrapped for 30 samples, with 241 observations from source 1 and 305 observations from source 2 per sample, for additional exploration of the completeness of pulmonary tuberculosis. The results from the original data show that the Chapman’s estimator gave the estimation of a total 360 (95% CI: 349-371) pulmonary tuberculosis cases, resulting in 57% estimated completeness cases. But the Chao’s lower bound estimator estimated the total of 365 (95% CI: 354-376) pulmonary tuberculosis cases and its estimated completeness cases was 55.9%. For the results from bootstrap samples, the Chapman and the Chao’s lower bound estimators gave an estimated 347 (95% CI: 309-385) and 353 (95% CI: 315-390) pulmonary tuberculosis cases, respectively. If for two sources recoding systems are available, record-linkage and capture-recapture analysis can be useful for estimating the completeness of different registration system. Both Chapman and Chao’s lower bound estimator approaches produce very close estimates. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=capture-recapture" title="capture-recapture">capture-recapture</a>, <a href="https://publications.waset.org/abstracts/search?q=Chao" title=" Chao"> Chao</a>, <a href="https://publications.waset.org/abstracts/search?q=Chapman" title=" Chapman"> Chapman</a>, <a href="https://publications.waset.org/abstracts/search?q=pulmonary%20tuberculosis" title=" pulmonary tuberculosis"> pulmonary tuberculosis</a> </p> <a href="https://publications.waset.org/abstracts/23818/capture-recapture-to-estimate-completeness-of-pulmonary-tuberculosis-with-two-sources" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/23818.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">516</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">619</span> Cadaveric Study of Lung Anatomy: A Surgical Overview</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Arthi%20Ganapathy">Arthi Ganapathy</a>, <a href="https://publications.waset.org/abstracts/search?q=Rati%20Tandon"> Rati Tandon</a>, <a href="https://publications.waset.org/abstracts/search?q=Saroj%20Kaler"> Saroj Kaler</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: A thorough knowledge of variations in lung anatomy is of prime significance during surgical procedures like lobectomy, pneumonectomy, and segmentectomy of lungs. The arrangement of structures in the lung hilum act as a guide in performing such procedures. The normal pattern of arrangement of hilar structures in the right lung is eparterial bronchus, pulmonary artery, hyparterial bronchus and pulmonary veins from above downwards. In the left lung, it is pulmonary artery, principal bronchus and pulmonary vein from above downwards. The arrangement of hilar structures from anterior to posterior in both the lungs is pulmonary vein, pulmonary artery, and principal bronchus. The bronchial arteries are very small and usually the posterior most structures in the hilum of lungs. Aim: The present study aims at reporting the variations in hilar anatomy (arrangement and number) of lungs. Methodology: 75 adult formalin fixed cadaveric lungs from the department of Anatomy AIIMS New Delhi were observed for variations in the lobar anatomy. Arrangement of pulmonary hilar structures was meticulously observed, and any deviation in the pattern of presentation was recorded. Results: Among the 75 adult lung specimens observed 36 specimens were of right lung and the rest of left lung. Seven right lung specimens showed only 2 lobes with an oblique fissure dividing them and one left lung showed 3 lobes. The normal pattern of arrangement of hilar structures was seen in 22 right lungs and 23 left lungs. Rest of the lung specimens (14 right and 16 left) showed a varied pattern of arrangement of hilar structures. Some of them showed alterations in the sequence of arrangement of pulmonary artery, pulmonary veins, bronchus, and others in the number of these structures. Conclusion: Alterations in the pattern of arrangement of structures in the lung hilum are quite frequent. A compromise in knowledge of such variations will result in inadvertent complications like intraoperative bleeding during surgical procedures. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=fissures" title="fissures">fissures</a>, <a href="https://publications.waset.org/abstracts/search?q=hilum" title=" hilum"> hilum</a>, <a href="https://publications.waset.org/abstracts/search?q=lobes" title=" lobes"> lobes</a>, <a href="https://publications.waset.org/abstracts/search?q=pulmonary" title=" pulmonary"> pulmonary</a> </p> <a href="https://publications.waset.org/abstracts/77925/cadaveric-study-of-lung-anatomy-a-surgical-overview" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/77925.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">224</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">618</span> Design and Development of a Bi-Leaflet Pulmonary Valve</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Munirah%20Ismail">Munirah Ismail</a>, <a href="https://publications.waset.org/abstracts/search?q=Joon%20Hock%20Yeo"> Joon Hock Yeo</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Paediatric patients who require ventricular outflow tract reconstruction usually need valve construction to prevent valvular regurgitation. They would face problems like lack of suitable, affordable conduits and the need to undergo several operations in their lifetime due to the short lifespan of existing valves. Their natural growth and development are also of concern, even if they manage to receive suitable conduits. Current prosthesis including homografts, bioprosthetic valves, mechanical valves, and bovine jugular veins either do not have the long-term durability or the ability to adapt to the growth of such patients. We have developed a new design of bi-leaflet valve. This new technique accommodates patients’ annular size growth while maintaining valvular patency. A mock circulatory system was set up to assess the hemodynamic performance of the bi-leaflet pulmonary valve. It was found that the percentage regurgitation was acceptable and thus, validates this novel concept. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bi-leaflet%20pulmonary%20valve" title="bi-leaflet pulmonary valve">bi-leaflet pulmonary valve</a>, <a href="https://publications.waset.org/abstracts/search?q=pulmonary%20heart%20valve" title=" pulmonary heart valve"> pulmonary heart valve</a>, <a href="https://publications.waset.org/abstracts/search?q=tetralogy%20of%20fallot" title=" tetralogy of fallot"> tetralogy of fallot</a>, <a href="https://publications.waset.org/abstracts/search?q=mock%20circulatory%20system" title=" mock circulatory system"> mock circulatory system</a> </p> <a href="https://publications.waset.org/abstracts/86147/design-and-development-of-a-bi-leaflet-pulmonary-valve" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/86147.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">162</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">617</span> Algorithm for Quantification of Pulmonary Fibrosis in Chest X-Ray Exams</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Marcela%20de%20Oliveira">Marcela de Oliveira</a>, <a href="https://publications.waset.org/abstracts/search?q=Guilherme%20Giacomini"> Guilherme Giacomini</a>, <a href="https://publications.waset.org/abstracts/search?q=Allan%20Felipe%20Fattori%20Alves"> Allan Felipe Fattori Alves</a>, <a href="https://publications.waset.org/abstracts/search?q=Ana%20Luiza%20Menegatti%20Pavan"> Ana Luiza Menegatti Pavan</a>, <a href="https://publications.waset.org/abstracts/search?q=Maria%20Eugenia%20Dela%20Rosa"> Maria Eugenia Dela Rosa</a>, <a href="https://publications.waset.org/abstracts/search?q=Fernando%20Antonio%20Bacchim%20Neto"> Fernando Antonio Bacchim Neto</a>, <a href="https://publications.waset.org/abstracts/search?q=Diana%20Rodrigues%20de%20Pina"> Diana Rodrigues de Pina</a> </p> <p class="card-text"><strong>Abstract:</strong></p> It is estimated that each year one death every 10 seconds (about 2 million deaths) in the world is attributed to tuberculosis (TB). Even after effective treatment, TB leaves sequelae such as, for example, pulmonary fibrosis, compromising the quality of life of patients. Evaluations of the aforementioned sequel are usually performed subjectively by radiology specialists. Subjective evaluation may indicate variations inter and intra observers. The examination of x-rays is the diagnostic imaging method most accomplished in the monitoring of patients diagnosed with TB and of least cost to the institution. The application of computational algorithms is of utmost importance to make a more objective quantification of pulmonary impairment in individuals with tuberculosis. The purpose of this research is the use of computer algorithms to quantify the pulmonary impairment pre and post-treatment of patients with pulmonary TB. The x-ray images of 10 patients with TB diagnosis confirmed by examination of sputum smears were studied. Initially the segmentation of the total lung area was performed (posteroanterior and lateral views) then targeted to the compromised region by pulmonary sequel. Through morphological operators and the application of signal noise tool, it was possible to determine the compromised lung volume. The largest difference found pre- and post-treatment was 85.85% and the smallest was 54.08%. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=algorithm" title="algorithm">algorithm</a>, <a href="https://publications.waset.org/abstracts/search?q=radiology" title=" radiology"> radiology</a>, <a href="https://publications.waset.org/abstracts/search?q=tuberculosis" title=" tuberculosis"> tuberculosis</a>, <a href="https://publications.waset.org/abstracts/search?q=x-rays%20exam" title=" x-rays exam"> x-rays exam</a> </p> <a href="https://publications.waset.org/abstracts/39759/algorithm-for-quantification-of-pulmonary-fibrosis-in-chest-x-ray-exams" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/39759.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">418</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">616</span> Trend and Incidence of Tuberculosis, Yemen, 2019 to 2021</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Zainab%20A.%20Alaghbri">Zainab A. Alaghbri</a>, <a href="https://publications.waset.org/abstracts/search?q=Labiba%20A."> Labiba A.</a>, <a href="https://publications.waset.org/abstracts/search?q=Esam%20A."> Esam A.</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Tuberculosis (TB) is the fourth leading cause of death in Yemen and is considered a major priority by the Ministry of Public Health. The war in Yemen has led to the emergence of one of the worst humanitarian crises in the world. These circumstances may lead to exacerbate the situation of tuberculosis. This study aims to describe the trend and incidence of TB in north and east governorates, Yemen 2019-2021 and provide recommendations for interventions. A descriptive analysis was conducted during July to September 2022. Data of TB cases were obtained from the national tuberculosis program as soft copy. The Data included the TB case collected and diagnosed during 2019-2021. The data contains the following variables: Sex, age, governorates, smear-positive cases, extra-pulmonary cases, and treatment outcomes. 16791 TB cases were notified for an overall case notification rate 65.5/100000 for all forms (smear positive and Extra-pulmonary), There was a slightly declined in 2020 and 2021 by 1%. Both the pulmonary smear positive and Extra pulmonary rates were slightly decreased from 8.8 to 7.7 and 13.5 to 12.8 / 100, 000 populations respectively. For Tuberculosis cases by type of patient, the incidence of extra-pulmonary was the highest (12,9, 11.3 and 12,2/100000) over the three years. However, the incidence of pulmonary failure was the lowest. The majority of cases were in the age group 25-34. The overall treatment success rate for smear-positive patients was 88%. Of the 627 patients with documented unsuccessful outcomes (e.g., failure, death, and default), 165 (23%) died, 52 (8.3%) failed treatment, and 410 (65%) defaulted. Overall, the magnitude of tuberculosis decreased over the periods reviewed. The proportion of Extra-pulmonary TB was the highest. The success rate achieved after treatment was below the levels established by the WHO End Tuberculosis Strategy (90%). Failure to complete treatment may be responsible for the low success rate. Monitoring and addressing the risk factors that were associated with treatment outcomes and duration may help improve the likelihood of achieving favorable outcomes among cases of smear-positive pulmonary TB. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=tuberculosis" title="tuberculosis">tuberculosis</a>, <a href="https://publications.waset.org/abstracts/search?q=trend" title=" trend"> trend</a>, <a href="https://publications.waset.org/abstracts/search?q=incidence" title=" incidence"> incidence</a>, <a href="https://publications.waset.org/abstracts/search?q=yemen" title=" yemen"> yemen</a> </p> <a href="https://publications.waset.org/abstracts/171629/trend-and-incidence-of-tuberculosis-yemen-2019-to-2021" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/171629.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">97</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">615</span> An Acerbate Psychotics Symptoms, Social Support, Stressful Life Events, Medication Use Self-Efficacy Impact on Social Dysfunction: A Cross Sectional Self-Rated Study of Persons with Schizophrenia Patient and Misusing Methamphetamines</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ek-Uma%20Imkome">Ek-Uma Imkome</a>, <a href="https://publications.waset.org/abstracts/search?q=Jintana%20Yunibhand"> Jintana Yunibhand</a>, <a href="https://publications.waset.org/abstracts/search?q=Waraporn%20Chaiyawat"> Waraporn Chaiyawat</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Persons with schizophrenia patient and misusing methamphetamines suffering from social dysfunction that impact on their quality of life. Knowledge of factors related to social dysfunction will guide the effective intervention. Objectives: To determine the direct effect, indirect effect and total effect of an acerbate Psychotics&rsquo; Symptoms, Social Support, Stressful life events, Medication use self-efficacy impact on social dysfunction in Thai schizophrenic patient and methamphetamine misuse. Methods: Data were collected from schizophrenic and methamphetamine misuse patient by self report. A linear structural relationship was used to test the hypothesized path model. Results: The hypothesized model was found to fit the empirical data and explained 54% of the variance of the psychotic symptoms (X<sup>2</sup> = 114.35, df = 92, p-value = 0.05, X<sup>2</sup> /df = 1.24, GFI = 0.96, AGFI = 0.92, CFI = 1.00, NFI = 0.99, NNFI = 0.99, RMSEA = 0.02). The highest total effect on social dysfunction was psychotic symptoms (0.67, p&lt;0.05). Medication use self-efficacy had a direct effect on psychotic symptoms (-0.25, p&lt;0.01), and social support had direct effect on medication use self efficacy (0.36, p &lt;0.01). Conclusions: Psychotic symptoms and stressful life events were the significance factors that influenced direct on social dysfunctioning. Therefore, interventions that are designed to manage these factors are crucial in order to enhance social functioning in this population. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=psychotic%20symptoms" title="psychotic symptoms">psychotic symptoms</a>, <a href="https://publications.waset.org/abstracts/search?q=methamphetamine" title=" methamphetamine"> methamphetamine</a>, <a href="https://publications.waset.org/abstracts/search?q=schizophrenia" title=" schizophrenia"> schizophrenia</a>, <a href="https://publications.waset.org/abstracts/search?q=stressful%20life%20events" title=" stressful life events"> stressful life events</a>, <a href="https://publications.waset.org/abstracts/search?q=social%20dysfunction" title=" social dysfunction"> social dysfunction</a>, <a href="https://publications.waset.org/abstracts/search?q=social%20support" title=" social support"> social support</a>, <a href="https://publications.waset.org/abstracts/search?q=medication%20use%20self%20efficacy" title=" medication use self efficacy"> medication use self efficacy</a> </p> <a href="https://publications.waset.org/abstracts/61816/an-acerbate-psychotics-symptoms-social-support-stressful-life-events-medication-use-self-efficacy-impact-on-social-dysfunction-a-cross-sectional-self-rated-study-of-persons-with-schizophrenia-patient-and-misusing-methamphetamines" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/61816.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">208</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">614</span> High-Dimensional Single-Cell Imaging Maps Inflammatory Cell Types in Pulmonary Arterial Hypertension</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Selena%20Ferrian">Selena Ferrian</a>, <a href="https://publications.waset.org/abstracts/search?q=Erin%20Mccaffrey"> Erin Mccaffrey</a>, <a href="https://publications.waset.org/abstracts/search?q=Toshie%20Saito"> Toshie Saito</a>, <a href="https://publications.waset.org/abstracts/search?q=Aiqin%20Cao"> Aiqin Cao</a>, <a href="https://publications.waset.org/abstracts/search?q=Noah%20Greenwald"> Noah Greenwald</a>, <a href="https://publications.waset.org/abstracts/search?q=Mark%20Robert%20Nicolls"> Mark Robert Nicolls</a>, <a href="https://publications.waset.org/abstracts/search?q=Trevor%20Bruce"> Trevor Bruce</a>, <a href="https://publications.waset.org/abstracts/search?q=Roham%20T.%20Zamanian"> Roham T. Zamanian</a>, <a href="https://publications.waset.org/abstracts/search?q=Patricia%20Del%20Rosario"> Patricia Del Rosario</a>, <a href="https://publications.waset.org/abstracts/search?q=Marlene%20Rabinovitch"> Marlene Rabinovitch</a>, <a href="https://publications.waset.org/abstracts/search?q=Michael%20Angelo"> Michael Angelo</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Recent experimental and clinical observations are advancing immunotherapies to clinical trials in pulmonary arterial hypertension (PAH). However, comprehensive mapping of the immune landscape in pulmonary arteries (PAs) is necessary to understand how immune cell subsets interact to induce pulmonary vascular pathology. We used multiplexed ion beam imaging by time-of-flight (MIBI-TOF) to interrogate the immune landscape in PAs from idiopathic (IPAH) and hereditary (HPAH) PAH patients. Massive immune infiltration in I/HPAH was observed with intramural infiltration linked to PA occlusive changes. The spatial context of CD11c+DCs expressing SAMHD1, TIM-3 and IDO-1 within immune-enriched microenvironments and neutrophils were associated with greater immune activation in HPAH. Furthermore, CD11c-DC3s (mo-DC-like cells) within a smooth muscle cell (SMC) enriched microenvironment were linked to vessel score, proliferating SMCs, and inflamed endothelial cells. Experimental data in cultured cells reinforced a causal relationship between neutrophils and mo-DCs in mediating pulmonary arterial SMC proliferation. These findings merit consideration in developing effective immunotherapies for PAH. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=pulmonary%20arterial%20hypertension" title="pulmonary arterial hypertension">pulmonary arterial hypertension</a>, <a href="https://publications.waset.org/abstracts/search?q=vascular%20remodeling" title=" vascular remodeling"> vascular remodeling</a>, <a href="https://publications.waset.org/abstracts/search?q=indoleamine%202-3-dioxygenase%201%20%28IDO-1%29" title=" indoleamine 2-3-dioxygenase 1 (IDO-1)"> indoleamine 2-3-dioxygenase 1 (IDO-1)</a>, <a href="https://publications.waset.org/abstracts/search?q=neutrophils" title=" neutrophils"> neutrophils</a>, <a href="https://publications.waset.org/abstracts/search?q=monocyte-derived%20dendritic%20cells" title=" monocyte-derived dendritic cells"> monocyte-derived dendritic cells</a>, <a href="https://publications.waset.org/abstracts/search?q=BMPR2%20mutation" title=" BMPR2 mutation"> BMPR2 mutation</a>, <a href="https://publications.waset.org/abstracts/search?q=interferon%20gamma%20%28IFN-%CE%B3%29" title=" interferon gamma (IFN-γ)"> interferon gamma (IFN-γ)</a> </p> <a href="https://publications.waset.org/abstracts/156849/high-dimensional-single-cell-imaging-maps-inflammatory-cell-types-in-pulmonary-arterial-hypertension" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/156849.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">173</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">613</span> Analysis of Formyl Peptide Receptor 1 Protein Value as an Indicator of Neutrophil Chemotaxis Dysfunction in Aggressive Periodontitis</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Prajna%20Metta">Prajna Metta</a>, <a href="https://publications.waset.org/abstracts/search?q=Yanti%20Rusyanti"> Yanti Rusyanti</a>, <a href="https://publications.waset.org/abstracts/search?q=Nunung%20Rusminah"> Nunung Rusminah</a>, <a href="https://publications.waset.org/abstracts/search?q=Bremmy%20Laksono"> Bremmy Laksono</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The decrease of neutrophil chemotaxis function may cause increased susceptibility to aggressive periodontitis (AP). Neutrophil chemotaxis is affected by formyl peptide receptor 1 (FPR1), which when activated will respond to bacterial chemotactic peptide formyl methionyl leusyl phenylalanine (FMLP). FPR1 protein value is decreased in response to a wide number of inflammatory stimuli in AP patients. This study was aimed to assess the alteration of FPR1 protein value in AP patients and if FPR1 protein value could be used as an indicator of neutrophil chemotaxis dysfunction in AP. This is a case control study with 20 AP patients and 20 control subjects. Three milliliters of peripheral blood were drawn and analyzed for FPR1 protein value with ELISA. The data were statistically analyzed with Mann-Whitney test (p&gt;0,05<u>)</u>. Results showed that the mean value of FPR1 protein value in AP group is 0,353 pg/mL (0,11 to 1,18 pg/mL) and the mean value of FPR1 protein value in control group is 0,296 pg/mL (0,05 to 0,88 pg/mL). P value 0,787 &gt; 0,05 suggested that there is no significant difference of FPR1 protein value in both groups. The present study suggests that FPR1 protein value has no significance alteration in AP patients and could not be used as an indicator of neutrophil chemotaxis dysfunction. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=aggressive%20periodontitis" title="aggressive periodontitis">aggressive periodontitis</a>, <a href="https://publications.waset.org/abstracts/search?q=chemotaxis%20dysfunction" title=" chemotaxis dysfunction"> chemotaxis dysfunction</a>, <a href="https://publications.waset.org/abstracts/search?q=FPR1%20protein%20value" title=" FPR1 protein value"> FPR1 protein value</a>, <a href="https://publications.waset.org/abstracts/search?q=neutrophil" title=" neutrophil"> neutrophil</a> </p> <a href="https://publications.waset.org/abstracts/58541/analysis-of-formyl-peptide-receptor-1-protein-value-as-an-indicator-of-neutrophil-chemotaxis-dysfunction-in-aggressive-periodontitis" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/58541.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">217</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">612</span> Bronchoscopy and Genexpert in the Diagnosis of Pulmonary Tuberculosis in the Indian Private Health Sector: A Short Case Series</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=J.%20J.%20Mathew">J. J. Mathew</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Pulmonary tuberculosis is highly prevalent in the Indian subcontinent. Most cases of pulmonary tuberculosis are diagnosed with sputum examinations and the vast majority of these are undertaken by the government run establishments. However, mycobacterial cultures are not routinely done, unless drug resistance is detected based on clinical response. Modern diagnostic tests like bronchoscopy and Genexpert are not routinely employed in the government institutions for the diagnosis of pulmonary tuberculosis, but have been accepted widely by good private institutions. The utility of these investigations in the private sector is not yet well recognized. This retrospective study aims to assess the usefulness of bronchoscopy and Genexpert in the diagnosis of pulmonary tuberculosis in quaternary care private hospital in India. 30 patients with respiratory symptoms raising the possibility of tuberculosis based on clinical and radiological features, but without any significant sputum production, were subject to bronchoscopy and BAL samples taken for microbiological studies, including Genexpert. 6 out of the 30 patients were found to be Genexpert positive and none of them showed Rifampicin resistance. All the 6 cases had upper zone predominant disease. One of the 6 cases of tuberculosis had another co-existent bacterial infection according to the routine culture studies. 6 other cases were proven to be due to other bacterial infections alone, 2 had a malignant diagnosis and the remaining cases were thought to be non-infective pathologies. The Genexpert results were made available within 48 hours in the 6 positive cases. All of them were commenced on standard anti-tuberculous regimen with excellent clinical response. The other infective cases were also managed successfully based on the drug susceptibilities. The study has shown the usefulness of these investigations as early intervention enabled diagnosis facilitating treatment and prevention of any clinical deterioration. The study lends support to early bronchoscopy and Genexpert testing in suspected cases of pulmonary tuberculosis without significant sputum production, in a high prevalence country which normally relies on sputum examination for the diagnosis of pulmonary tuberculosis. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=pulmonary" title="pulmonary">pulmonary</a>, <a href="https://publications.waset.org/abstracts/search?q=tuberculosis" title=" tuberculosis"> tuberculosis</a>, <a href="https://publications.waset.org/abstracts/search?q=bronchoscopy" title=" bronchoscopy"> bronchoscopy</a>, <a href="https://publications.waset.org/abstracts/search?q=genexpert" title=" genexpert"> genexpert</a> </p> <a href="https://publications.waset.org/abstracts/47668/bronchoscopy-and-genexpert-in-the-diagnosis-of-pulmonary-tuberculosis-in-the-indian-private-health-sector-a-short-case-series" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/47668.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">245</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">611</span> Adequacy of Second-Generation Laryngeal Mask Airway during Prolonged Abdominal Surgery</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sukhee%20Park">Sukhee Park</a>, <a href="https://publications.waset.org/abstracts/search?q=Gaab%20Soo%20Kim"> Gaab Soo Kim</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Purpose: We aimed to evaluate the adequacy of second-generation laryngeal mask airway use during prolonged abdominal surgery in respect of ventilation, oxygenation, postoperative pulmonary complications (PPC), and postoperative non-pulmonary complications on living donor kidney transplant (LDKT) surgery. Methods: In total, 257 recipients who underwent LDKT using either laryngeal mask airway-ProSeal (LMA-P) or endotracheal tube (ETT) were retrospectively analyzed. Arterial partial pressure of carbon dioxide (PaCO2 and ratio of arterial partial pressure of oxygen to fractional inspired oxygen (PFR) during surgery were compared between two groups. In addition, PPC including pulmonary aspiration and postoperative non-pulmonary complications including nausea, vomiting, hoarseness, vocal cord palsy, delirium, and atrial fibrillation were also compared. Results: PaCO2 and PFR during surgery were not significantly different between the two groups. PPC was also not significantly different between the two groups. Interestingly, the incidence of delirium was significantly lower in the LMA-P group than the ETT group (3.0% vs. 10.3%, P = 0.029). Conclusions: During prolonged abdominal surgery such as LDKT, second-generation laryngeal mask airway offers adequate ventilation and oxygenation and can be considered a suitable alternative to ETT. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=laryngeal%20mask%20airway" title="laryngeal mask airway">laryngeal mask airway</a>, <a href="https://publications.waset.org/abstracts/search?q=prolonged%20abdominal%20surgery" title=" prolonged abdominal surgery"> prolonged abdominal surgery</a>, <a href="https://publications.waset.org/abstracts/search?q=kidney%20transplantation" title=" kidney transplantation"> kidney transplantation</a>, <a href="https://publications.waset.org/abstracts/search?q=postoperative%20pulmonary%20complication" title=" postoperative pulmonary complication"> postoperative pulmonary complication</a> </p> <a href="https://publications.waset.org/abstracts/100086/adequacy-of-second-generation-laryngeal-mask-airway-during-prolonged-abdominal-surgery" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/100086.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">148</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">610</span> Developing HRCT Criterion to Predict the Risk of Pulmonary Tuberculosis</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Vandna%20Raghuvanshi">Vandna Raghuvanshi</a>, <a href="https://publications.waset.org/abstracts/search?q=Vikrant%20Thakur"> Vikrant Thakur</a>, <a href="https://publications.waset.org/abstracts/search?q=Anupam%20Jhobta"> Anupam Jhobta</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Objective: To design HRCT criterion to forecast the threat of pulmonary tuberculosis. Material and methods: This was a prospective study of 69 patients with clinical suspicion of pulmonary tuberculosis. We studied their medical characteristics, numerous separate HRCT-results, and a combination of HRCT findings to foresee the danger for PTB by utilizing univariate and multivariate investigation. Temporary HRCT diagnostic criteria were planned in view of these outcomes to find out the risk of PTB and tested these criteria on our patients. Results: The results of HRCT chest were analyzed, and Rank was given from 1 to 4 according to the HRCT chest findings. Sensitivity, specificity, positive predictive value, and negative predictive value were calculated. Rank 1: Highly suspected PTB. Rank 2: Probable PTB Rank 3: Nonspecific or difficult to differentiate from other diseases Rank 4: Other suspected diseases • Rank 1 (Highly suspected TB) was present in 22 (31.9%) patients, all of them finally diagnosed to have pulmonary tuberculosis. The sensitivity, specificity, and negative likelihood ratio for RANK 1 on HRCT chest was 53.6%, 100%, and 0.43, respectively. • Rank 2 (Probable TB) was present in 13 patients, out of which 12 were tubercular, and 1 was non-tubercular. • The sensitivity, specificity, positive likelihood ratio, and negative likelihood ratio of the combination of Rank 1 and Rank 2 was 82.9%, 96.4%, 23.22, and 0.18, respectively. • Rank 3 (Non-specific TB) was present in 25 patients, and out of these, 7 were tubercular, and 18 were non-tubercular. • When all these 3 ranks were considered together, the sensitivity approached 100% however, the specificity reduced to 35.7%. The positive likelihood ratio and negative likelihood ratio were 1.56 and 0, respectively. • Rank 4 (Other specific findings) was given to 9 patients, and all of these were non-tubercular. Conclusion: HRCT is useful in selecting individuals with greater chances of pulmonary tuberculosis. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=pulmonary" title="pulmonary">pulmonary</a>, <a href="https://publications.waset.org/abstracts/search?q=tuberculosis" title=" tuberculosis"> tuberculosis</a>, <a href="https://publications.waset.org/abstracts/search?q=multivariate" title=" multivariate"> multivariate</a>, <a href="https://publications.waset.org/abstracts/search?q=HRCT" title=" HRCT"> HRCT</a> </p> <a href="https://publications.waset.org/abstracts/142334/developing-hrct-criterion-to-predict-the-risk-of-pulmonary-tuberculosis" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/142334.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">172</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">609</span> Changes in Pulmonary Functions in Diabetes Mellitus Type 2</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=N.%20Anand">N. Anand</a>, <a href="https://publications.waset.org/abstracts/search?q=P.%20S.%20Nayyer"> P. S. Nayyer</a>, <a href="https://publications.waset.org/abstracts/search?q=V.%20Rana"> V. Rana</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20Verma"> S. Verma</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Diabetes mellitus is a group of disorders characterized by hyperglycemia and associated with microvascular and macrovascular complications. Among the lesser known complications is the involvement of respiratory system. Changes in pulmonary volume, diffusion and elastic properties of lungs as well as the performance of the respiratory muscles lead to a restrictive pattern in lung functions. The present study was aimed to determine the changes in various parameters of pulmonary function tests amongst patients with Type 2 Diabetes Mellitus and also try to study the effect of duration of Diabetes Mellitus on pulmonary function tests. Methods: It was a cross sectional study performed at Dr Baba Saheb Ambedkar Hospital and Medical College in, Delhi, A Tertiary care referral centre which included 200 patients divided into 2 groups. The first group included diagnosed patients with diabetes and the second group included controls. Cases and controls symptomatic for any acute or chronic Respiratory or Cardiovascular illness or a history of smoking were excluded. Both the groups were subjected to spirometry to evaluate for the pulmonary function tests. Result: The mean Forced Vital Capacity (FVC), Forced Expiratory Volume in first second (FEV1), Peak Expiratory Flow Rate(PEFR) was found to be significantly decreased ((P < 0.001) as compared to controls while the mean ratio of Forced Expiratory Volume in First second to Forced Vital Capacity was not significantly decreased( p>0.005). There was no correlation seen with duration of the disease. Conclusion: Forced Vital Capacity (FVC), Forced Expiratory Volume in first second (FEV1), Peak Expiratory Flow Rate(PEFR) were found to be significantly decreased in patients of Diabetes mellitus while ratio of Forced Expiratory Volume in First second to Forced Vital Capacity (FEV1/FVC) was not significantly decreased. The duration of Diabetes mellitus was not found to have any statistically significant effect on Pulmonary function tests (p > 0.005). <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=diabetes%20mellitus" title="diabetes mellitus">diabetes mellitus</a>, <a href="https://publications.waset.org/abstracts/search?q=pulmonary%20function%20tests" title=" pulmonary function tests"> pulmonary function tests</a>, <a href="https://publications.waset.org/abstracts/search?q=forced%20vital%20capacity" title=" forced vital capacity"> forced vital capacity</a>, <a href="https://publications.waset.org/abstracts/search?q=forced%20expiratory%20volume%20in%20first%20second" title=" forced expiratory volume in first second"> forced expiratory volume in first second</a> </p> <a href="https://publications.waset.org/abstracts/39865/changes-in-pulmonary-functions-in-diabetes-mellitus-type-2" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/39865.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">368</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">608</span> Half Dose Tissue Plasminogen Activator for Intermediate-Risk Pulmonary Embolism</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Macie%20Matta">Macie Matta</a>, <a href="https://publications.waset.org/abstracts/search?q=Ahmad%20Jabri"> Ahmad Jabri</a>, <a href="https://publications.waset.org/abstracts/search?q=Stephanie%20Jackson"> Stephanie Jackson</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: In the absence of hypotension, pulmonary embolism (PE) causing right ventricular dysfunction or strain, whether confirmed by imaging or cardiac biomarkers, is deemed to be an intermediate-risk category. Urgent treatment of intermediate-risk PE can prevent progression to hemodynamic instability and death. Management options include thrombolysis, thrombectomy, or systemic anticoagulation. We aim to evaluate the short-term outcomes of a half-dose tissue plasminogen activator (tPA) for the management of intermediate-risk PE. Methods: We retrospectively identified adult patients diagnosed with intermediate-risk PE between the years 2000 and 2021. Demographic data, lab values, imaging, treatment choice, and outcomes were all obtained through chart review. Primary outcomes measured include major bleeding events and in-hospital mortality. Patients on standard systemic anticoagulation without receiving thrombolysis or thrombectomy served as controls. Patient data were analyzed using SAS®️ Software (version 9.4; Cary, NC) to compare individuals that received half-dose tPA with controls, and statistical significance was set at a p-value of 0.05. Results: We included 57 patients in our final analysis, with 19 receiving tPA. Patient characteristics and comorbidities were comparable between both groups. There was a significant difference between PE location, presence of acute deep vein thrombosis, and peak troponin level between both groups. The thrombolytic cohort was more likely to demonstrate a 60/60 sign and thrombus in transit finding on echocardiography than controls. The thrombolytic group was more likely to have major bleeding (17% vs 7.9%, p= 0.4) and in-hospital mortality (5.3% vs 0%, p=0.3); however, this was not statistically significant. Patients who received half-dose tPA had non-significantly higher rates of major bleeding and in-hospital mortality. Larger scale, randomized control trials are needed to establish the benefit and safety of thrombolytics in patients with intermediate-risk PE. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=pulmonary%20embolism" title="pulmonary embolism">pulmonary embolism</a>, <a href="https://publications.waset.org/abstracts/search?q=half%20dose%20thrombolysis" title=" half dose thrombolysis"> half dose thrombolysis</a>, <a href="https://publications.waset.org/abstracts/search?q=tissue%20plasminogen%20activator" title=" tissue plasminogen activator"> tissue plasminogen activator</a>, <a href="https://publications.waset.org/abstracts/search?q=cardiac%20biomarkers" title=" cardiac biomarkers"> cardiac biomarkers</a>, <a href="https://publications.waset.org/abstracts/search?q=echocardiographic%20findings" title=" echocardiographic findings"> echocardiographic findings</a>, <a href="https://publications.waset.org/abstracts/search?q=major%20bleeding%20event" title=" major bleeding event"> major bleeding event</a> </p> <a href="https://publications.waset.org/abstracts/161710/half-dose-tissue-plasminogen-activator-for-intermediate-risk-pulmonary-embolism" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/161710.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">75</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">607</span> Directly Observed Treatment Short-Course (DOTS) for TB Control Program: A Ten Years Experience </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Solomon%20Sisay">Solomon Sisay</a>, <a href="https://publications.waset.org/abstracts/search?q=Belete%20Mengistu"> Belete Mengistu</a>, <a href="https://publications.waset.org/abstracts/search?q=Woldargay%20Erku"> Woldargay Erku</a>, <a href="https://publications.waset.org/abstracts/search?q=Desalegne%20Woldeyohannes"> Desalegne Woldeyohannes</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Tuberculosis is still the leading cause of illness in the world which accounted for 2.5% of the global burden of disease, and 25% of all avoidable deaths in developing countries. Objectives: The aim of study was to assess impact of DOTS strategy on tuberculosis case finding and treatment outcome in Gambella Regional State, Ethiopia from 2003 up to 2012 and from 2002 up to 2011, respectively. Methods: Health facility-based retrospective study was conducted. Data were collected and reported in quarterly basis using WHO reporting format for TB case finding and treatment outcome from all DOTS implementing health facilities in all zones of the region to Federal Ministry of Health. Results: A total of 10024 all form of TB cases had been registered between the periods from 2003 up to 2012. Of them, 4100 (40.9%) were smear-positive pulmonary TB, 3164 (31.6%) were smear-negative pulmonary TB and 2760 (27.5%) had extra-pulmonary TB. Case detection rate of smear-positive pulmonary TB had increased from 31.7% to 46.5% from the total TB cases and treatment success rate increased from 13% to 92% with average mean value of being 40.9% (SD= 0.1) and 55.7% (SD=0.28), respectively for the specified year periods. Moreover, the average values of treatment defaulter and treatment failure rates were 4.2% and 0.3%, respectively. Conclusion: It is possible to achieve the recommended WHO target which is 70% of CDR for smear-positive pulmonary TB, and 85% of TSR as it was already been fulfilled the targets for treatments more than 85% from 2009 up to 2011 in the region. However, it requires strong efforts to enhance case detection rate of 40.9% for smear-positive pulmonary TB through implementing alternative case finding strategies. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Gambella%20Region" title="Gambella Region">Gambella Region</a>, <a href="https://publications.waset.org/abstracts/search?q=case%20detection%20rate" title=" case detection rate"> case detection rate</a>, <a href="https://publications.waset.org/abstracts/search?q=directly%20observed%20treatment%20short-course" title=" directly observed treatment short-course"> directly observed treatment short-course</a>, <a href="https://publications.waset.org/abstracts/search?q=treatment%20success%20rate" title=" treatment success rate"> treatment success rate</a>, <a href="https://publications.waset.org/abstracts/search?q=tuberculosis" title=" tuberculosis "> tuberculosis </a> </p> <a href="https://publications.waset.org/abstracts/2519/directly-observed-treatment-short-course-dots-for-tb-control-program-a-ten-years-experience" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/2519.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">344</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">606</span> Correlation between Creatinine Level with Erectile Dysfunction among Diabetics in Temerloh Health Clinic</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mohammad%20Zainie%20Bin%20Hassan">Mohammad Zainie Bin Hassan</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Erectile dysfunction (ED) is a complication commonly seen among men with diabetes which can be assessed based upon International Index of Erectile Function (IIEF-5) questionnaire. Creatinine level is a blood test that indicates kidney functionality. Object: To evaluate the association between ED, determined by the IIEF-5scores and Creatinine level in diabetic men attending Temerloh Health Clinic, Pahang, Malaysia.Hence, to identify raising Creatinine level related with ED or not. Methods: All married diabetic patients will be investigated face to face after consented for answering the IIEF-5 questionnaire. Creatinine level will be taken by using standard method.Patients with no sexual partner, refuse to answer the questionnaire, cancer, stroke, heart disease and language barrier will be excluded.Data obtained from IIEF-5 score and Creatinine level will be analyzed by using Pearson correlation. All statistical value determined by p=0.05. ED will be categorized accordingly to IIEF-5 scores: no ED (22-25), mild (17-21), moderate (12-16), severe (8-11) and very severe (1-7). Results: A total of 450 patients were investigated with 385 patients were included (85.6% respondant rate) and 65 patients were excluded in this study with age range from 29 to 85 years old. 7% had no ED, 28% mild ED, 34% moderate ED, 16% severe ED and 15% had very severe ED. There was a significant negative correlation between Creatinine level and IIEF-5 scores (r=-0.218, p <0.001). This result implicated that poor kidney function which indicated by high Creatinine level associated significantly with erectile dysfunction. 93% had ED with a different range of severity which triggers for appropriate aggressive ED management among diabetics. Conclusion: The high level of Creatinine is associated with erectile dysfunction among diabetics in Temerloh Health Clinic. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=correlation" title="correlation">correlation</a>, <a href="https://publications.waset.org/abstracts/search?q=creatinine%20level" title=" creatinine level"> creatinine level</a>, <a href="https://publications.waset.org/abstracts/search?q=erectile%20dysfunction" title=" erectile dysfunction"> erectile dysfunction</a>, <a href="https://publications.waset.org/abstracts/search?q=ED" title=" ED"> ED</a>, <a href="https://publications.waset.org/abstracts/search?q=diabetes" title=" diabetes"> diabetes</a> </p> <a href="https://publications.waset.org/abstracts/18778/correlation-between-creatinine-level-with-erectile-dysfunction-among-diabetics-in-temerloh-health-clinic" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/18778.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">409</span> </span> </div> </div> <ul class="pagination"> <li class="page-item disabled"><span class="page-link">&lsaquo;</span></li> <li class="page-item active"><span class="page-link">1</span></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=pulmonary%20dysfunction&amp;page=2">2</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=pulmonary%20dysfunction&amp;page=3">3</a></li> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=pulmonary%20dysfunction&amp;page=4">4</a></li> <li class="page-item"><a class="page-link" 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