CINXE.COM

<!DOCTYPE html><html lang="en"><head> <link rel=preload href="https://assets.healthline.com/_next/vendor-8da18-legacy.js" as=script crossorigin=anonymous><link rel=preload href="https://assets.healthline.com/_next/lib-939ee-legacy.js" as=script crossorigin=anonymous><link rel=preload href="https://assets.healthline.com/_next/felib-core-f46c4-legacy.js" as=script crossorigin=anonymous><link rel=preload href="https://assets.healthline.com/_next/b4a658d5-9338-4cd3-9e5d-9d0a6ca8e30c/hl/pages/infinite.js-legacy.js" as=script crossorigin=anonymous> <title>Endocannabinoid System: A Simple Guide to How It Works</title><link rel="canonical" href="https://www.healthline.com/health/endocannabinoid-system"/><meta name="description" content="The endocannabinoid is a complex system that still isn't fully understood. We'll go over what experts do know about it, including how it works, the ways it interacts with cannabis, and theories about its role in different conditions."/><meta name="keywords" content="endocannabinoid system"/><meta name="k1" content="marijuanause"/><meta name="k2" content="substanceuse"/><meta name="ROBOTS" content="NOODP"/><meta name="sailthru.image.thumb" content="https://media.post.rvohealth.io/wp-content/uploads/2019/04/Doctor_Talk_Female_Laptop-732x549-Thumbnail.jpg"/><meta name="sailthru.tags" content="marijuanause,substanceuse"/><meta name="article:published_time" content="2019-05-17T14:03:13.000Z"/><meta name="article:author" content="Crystal Raypole"/><meta property="og:title" content="Endocannabinoid System: A Simple Guide to How It Works"/><meta property="og:description" content="The endocannabinoid is a complex system that still isn't fully understood. We'll go over what experts do know about it, including how it works, the ways it interacts with cannabis, and theories about its role in different conditions."/><meta property="og:type" content="article"/><meta property="og:url" content="https://www.healthline.com/health/endocannabinoid-system"/><meta name="twitter:title" content="Endocannabinoid System: A Simple Guide to How It Works"/><meta name="twitter:description" content="The endocannabinoid is a complex system that still isn't fully understood. We'll go over what experts do know about it, including how it works, the ways it interacts with cannabis, and theories about its role in different conditions."/><meta name="twitter:card" content="summary_large_image"/><meta name="twitter:image" content="https://media.post.rvohealth.io/wp-content/uploads/2019/04/Doctor_Talk_Female_Laptop-732x549-Thumbnail.jpg"/><meta property="og:site_name" content="Healthline"/><meta name="twitter:site" content="@healthline"/><meta name="twitter:creator" content="@healthline"/><meta property="fb:app_id" content="1529595680591919"/><meta name="kmeta" content="eczema-predictive-aq,nsclc-predictive-aq,obesity-predictive-aq,bipolar-predictive-aq-1,bipolar-predictive-aq,vraylar24bp"/><meta property="og:image" content="https://media.post.rvohealth.io/wp-content/uploads/2019/04/Doctor_Talk_Female_Laptop-1200x628-Facebook.jpg"/><meta property="og:image:width" content="1200"/><meta property="og:image:height" content="628"/><meta property="og:image" content="https://media.post.rvohealth.io/wp-content/uploads/2019/04/Doctor_Talk_Female_Laptop-732x549-Thumbnail.jpg"/><meta property="og:image:width" content="732"/><meta property="og:image:height" content="549"/> <style data-emotion="css 0 1e4ja14 1pf0x3y 79elbk 7wivn5 1bnren8 1ujqk39 1v78rwm 1c2ok3c d2znx6 1oanbjp 114osio 198d8b5 h9jo37 u8uhak 1ub4i5m 1acbpvw rre5oz 1ndif92 1d75hb8 15lc7zf 10dx3t k1nhka 14uyzrw vrhe66 12wdr8u 16wahxh 12qvns3 19k7c2f ro87dg 12va8w7 1avyp1d 5sudr5 1ugaz02 1ivue52 1ti7iub dorrmn 7vynax 10ib5jr 2kgwd5 ck5ydc 13njx2h 3o9pqj upe1zs jwb353 1xdhyk6 1081t4c eqytyw v23quv 1qsp2zb 1vtpbs6 spwcx4 t143ak 1p4nzih v5yzal">.css-1e4ja14{text-align:center;font-size:0;line-height:0;}.css-1pf0x3y{width:100%;display:block;}.css-79elbk{position:relative;}@-webkit-keyframes animation-7wivn5{from{right:-600px;}to{right:0;}}@keyframes animation-7wivn5{from{right:-600px;}to{right:0;}}@-webkit-keyframes animation-1bnren8{from{right:0;visibility:visible;}to{right:-600px;visibility:hidden;}}@keyframes animation-1bnren8{from{right:0;visibility:visible;}to{right:-600px;visibility:hidden;}}@-webkit-keyframes animation-1ujqk39{from{right:-600px;display:none;}to{right:0;display:-webkit-box;display:-webkit-flex;display:-ms-flexbox;display:flex;}}@keyframes animation-1ujqk39{from{right:-600px;display:none;}to{right:0;display:-webkit-box;display:-webkit-flex;display:-ms-flexbox;display:flex;}}@-webkit-keyframes animation-1v78rwm{from{right:0;display:-webkit-box;display:-webkit-flex;display:-ms-flexbox;display:flex;}to{right:-600px;display:none;}}@keyframes animation-1v78rwm{from{right:0;display:-webkit-box;display:-webkit-flex;display:-ms-flexbox;display:flex;}to{right:-600px;display:none;}}.css-1c2ok3c{cursor:pointer;-webkit-text-decoration:none;text-decoration:none;border-color:currentColor;color:#02838d;}.css-1c2ok3c:hover{color:#08565c;}.css-1c2ok3c:hover img,.css-1c2ok3c:hover .image{opacity:0.8;}.css-1c2ok3c:hover svg{fill:currentColor;}.css-1c2ok3c:active{color:#9b1561;}.css-d2znx6{margin-bottom:25px;}.css-1oanbjp{margin:0 0 0 25px;padding:0;display:-webkit-box;display:-webkit-flex;display:-ms-flexbox;display:flex;list-style:none;}.css-114osio{display:-webkit-box;display:-webkit-flex;display:-ms-flexbox;display:flex;-webkit-align-items:center;-webkit-box-align:center;-ms-flex-align:center;align-items:center;margin-bottom:0;}.css-114osio svg{fill:#dcdbdb;}.css-114osio:last-child{margin-right:0;}.css-114osio:hover{color:#fcba44;}.css-114osio:hover svg{fill:#fcba44;}.css-114osio:hover button{color:#fcba44;}.css-198d8b5{font-family:Proxima Nova Condensed,Arial Narrow,helvetica,arial,system-ui,sans-serif;background-color:transparent;border:none;display:block;padding:20px 25px;margin-top:0;margin-bottom:0;-webkit-text-decoration:none;text-decoration:none;font-size:18px;line-height:24px;color:white;cursor:pointer;-webkit-transition:color 0.2s;transition:color 0.2s;}@media(min-width:768px){.css-198d8b5{font-size:18px;line-height:24px;}}@media(min-width:990px){.css-198d8b5{font-size:20px;line-height:28px;}}.css-198d8b5 svg{width:10px;height:10px;margin-left:6px;-webkit-transition:fill 0.2s;transition:fill 0.2s;fill:#dcdbdb;}.css-198d8b5:hover{color:#fcba44;}.css-198d8b5:hover svg{fill:#fcba44;}.css-h9jo37{height:1px;overflow:visible;}.css-1ub4i5m{margin-top:-15px;}@-webkit-keyframes animation-1acbpvw{0%{opacity:0;}100%{opacity:1;}}@keyframes animation-1acbpvw{0%{opacity:0;}100%{opacity:1;}}.css-rre5oz{display:-webkit-box;display:-webkit-flex;display:-ms-flexbox;display:flex;-webkit-flex-direction:row;-ms-flex-direction:row;flex-direction:row;-webkit-box-pack:start;-ms-flex-pack:start;-webkit-justify-content:flex-start;justify-content:flex-start;-webkit-align-items:center;-webkit-box-align:center;-ms-flex-align:center;align-items:center;padding-bottom:4px;text-transform:uppercase;color:#767474;font-family:"Proxima Nova","Proxima Nova Fallback",sans-serif;line-height:19px;}.css-rre5oz >span{font-weight:700;}.css-1ndif92{-webkit-animation:animation-1acbpvw 0.2s ease-in;animation:animation-1acbpvw 0.2s ease-in;display:none;overflow:hidden;}.css-1ndif92[open]{display:block;}.css-1ndif92>div{margin-bottom:0;}.css-1ndif92 ul li a{color:#02838d;}.css-1ndif92 ul li a:hover{color:#08565c;}.css-1d75hb8{height:20px;width:20px;margin-right:12px;}.css-1d75hb8 svg{fill:#767474;height:20px;width:20px;}.css-15lc7zf>h3{margin-bottom:12px;}.css-10dx3t{position:relative;margin-top:24px;}.css-k1nhka{position:absolute;top:0;right:0;color:#767474;z-index:1;}.css-k1nhka>p{font-size:14px;margin:0;}@media max-tablet{.css-k1nhka{position:static;display:-webkit-box;display:-webkit-flex;display:-ms-flexbox;display:flex;-webkit-box-flex-wrap:wrap;-webkit-flex-wrap:wrap;-ms-flex-wrap:wrap;flex-wrap:wrap;-webkit-box-pack:justify;-webkit-justify-content:space-between;justify-content:space-between;padding:16px 0;row-gap:8px;border-top:2px solid #dcdbdb;margin-top:24px;}.css-k1nhka>p{-webkit-flex-basis:100%;-ms-flex-preferred-size:100%;flex-basis:100%;}}.css-14uyzrw{height:25px;-webkit-align-items:center;-webkit-box-align:center;-ms-flex-align:center;align-items:center;display:-webkit-box;display:-webkit-flex;display:-ms-flexbox;display:flex;margin-right:-20px;}@media(min-width:768px){.css-14uyzrw{margin-right:-22px;}}.css-14uyzrw>.button-wrapper{margin-right:20px;color:#767474;}@media(min-width:768px){.css-14uyzrw>.button-wrapper{margin-right:22px;}}.css-14uyzrw>.button-wrapper>.button{font-size:20px;display:-webkit-box;display:-webkit-flex;display:-ms-flexbox;display:flex;-webkit-text-decoration:none;text-decoration:none;}.css-14uyzrw>.button-wrapper.print{display:none;}@media(min-width:768px){.css-14uyzrw>.button-wrapper.print{display:none;}}@media(min-width:990px){.css-14uyzrw>.button-wrapper.print{display:block;}}.css-14uyzrw>.button-wrapper.pinterest,.css-14uyzrw>.button-wrapper.reddit{display:none;}@media(min-width:768px){.css-14uyzrw>.button-wrapper.pinterest,.css-14uyzrw>.button-wrapper.reddit{display:block;}}.css-14uyzrw>.button-wrapper.more{display:block;}@media(min-width:768px){.css-14uyzrw>.button-wrapper.more{display:none;}}.css-vrhe66{display:-webkit-box;display:-webkit-flex;display:-ms-flexbox;display:flex;padding-bottom:0;gap:25px;-webkit-align-items:flex-start;-webkit-box-align:flex-start;-ms-flex-align:flex-start;align-items:flex-start;-webkit-box-pack:start;-ms-flex-pack:start;-webkit-justify-content:flex-start;justify-content:flex-start;}@media(min-width:768px){.css-vrhe66{padding-bottom:20px;gap:30px;}}.css-12wdr8u{position:-webkit-sticky;position:sticky;top:0;z-index:500;display:block;}.css-16wahxh{top:50px;z-index:401;pointer-events:none;position:-webkit-sticky;position:-webkit-sticky;position:sticky;}@media all and (-ms-high-contrast: none),(-ms-high-contrast: active){.css-16wahxh{padding-top:70px;}}.css-12qvns3{-webkit-align-items:center;-webkit-box-align:center;-ms-flex-align:center;align-items:center;display:-webkit-box;display:-webkit-flex;display:-ms-flexbox;display:flex;margin-left:0;margin-right:0;-webkit-order:4;-ms-flex-order:4;order:4;-webkit-flex:0 0 56px;-ms-flex:0 0 56px;flex:0 0 56px;-webkit-box-pack:end;-ms-flex-pack:end;-webkit-justify-content:flex-end;justify-content:flex-end;cursor:pointer;}@media(min-width:768px){.css-12qvns3{margin-left:0;margin-right:0;-webkit-order:4;-ms-flex-order:4;order:4;-webkit-flex:0 0 120px;-ms-flex:0 0 120px;flex:0 0 120px;-webkit-box-pack:end;-ms-flex-pack:end;-webkit-justify-content:flex-end;justify-content:flex-end;}}@media(min-width:990px){.css-12qvns3{margin-left:auto;margin-right:25px;-webkit-order:3;-ms-flex-order:3;order:3;-webkit-flex:0 1 auto;-ms-flex:0 1 auto;flex:0 1 auto;-webkit-box-pack:normal;-ms-flex-pack:normal;-webkit-justify-content:normal;justify-content:normal;}}.css-19k7c2f{cursor:pointer;color:white;font-family:Proxima Nova Condensed,Arial Narrow,helvetica,arial,system-ui,sans-serif;font-weight:500;font-size:12px;letter-spacing:0.21px;-webkit-transition:color 0.2s;transition:color 0.2s;text-transform:uppercase;}@media(min-width:768px){.css-19k7c2f{font-size:15px;}}@media(min-width:990px){.css-19k7c2f{font-size:18px;}}.css-19k7c2f:hover{color:#fcba44;}.css-ro87dg{color:#231f20;-webkit-text-decoration:underline;text-decoration:underline;}.css-12va8w7 p:first-of-type{margin-top:0px;padding-top:0px;}.css-12va8w7 p.disclaimer:first-of-type{padding-top:15px;}.css-12va8w7 .non-cost-jump-link{margin-bottom:30px;}.css-5sudr5{-webkit-appearance:none;-moz-appearance:none;-ms-appearance:none;appearance:none;background:none;border:none;padding:0;border-radius:0;margin-bottom:12px;font-size:16px;line-height:20px;cursor:pointer;}@media(min-width:768px){.css-5sudr5{overflow:hidden;}}.css-5sudr5[open]>div{border-bottom:2px solid #08565c;color:#08565c;}.css-5sudr5[open]>div span svg{fill:#08565c;}.css-1ugaz02{height:0;overflow:hidden;}.css-1ivue52{selector:css-oivvn2;overflow-wrap:break-word;word-break:break-word;word-wrap:break-word;}.css-1ti7iub{margin-bottom:25px;}.css-1ti7iub:last-child{margin-bottom:0;}.css-dorrmn{margin-top:25px;margin-bottom:50px;}.css-7vynax{display:block;position:absolute;top:0;left:0;height:100%;overflow:hidden;pointer-events:none;z-index:-1;}.css-10ib5jr{margin-bottom:40px;}.css-2kgwd5{margin-left:7px;position:relative;top:1px;}@media max-mobile{.css-2kgwd5{display:none;}}.css-ck5ydc{margin-right:0;}@media(min-width:768px){.css-ck5ydc{margin-right:0;}}@media(min-width:990px){.css-ck5ydc{margin-right:80px;}}.css-13njx2h{margin-bottom:50px;}@media(min-width:768px){.css-13njx2h{margin-bottom:0;}}.css-3o9pqj{width:40%;margin:0 20px;}@media(min-width:768px){.css-3o9pqj{width:40%;margin:0 20px;}}@media(min-width:990px){.css-3o9pqj{width:150px;margin:0 20px 0 0;}}.css-upe1zs{-webkit-flex:1;-ms-flex:1;flex:1;}.css-jwb353{display:none;}@media(min-width:768px){.css-jwb353{display:none;}}@media(min-width:990px){.css-jwb353{display:block;}}.css-1081t4c{-webkit-text-decoration:underline;text-decoration:underline;}.css-eqytyw{display:block;}@media(min-width:768px){.css-eqytyw{display:block;}}@media(min-width:990px){.css-eqytyw{display:none;}}.css-v23quv{margin-bottom:30px;}@media(min-width:768px){.css-v23quv{margin-bottom:30px;}}@media(min-width:990px){.css-v23quv{margin-bottom:0;}}.css-1qsp2zb{-webkit-flex-shrink:0;-ms-flex-negative:0;flex-shrink:0;}.css-1vtpbs6{width:auto;height:40px;margin-left:0;}@media(min-width:768px){.css-1vtpbs6{margin-left:0;}}@media(min-width:990px){.css-1vtpbs6{margin-left:50px;}}.css-spwcx4{width:auto;height:40px;}@-webkit-keyframes animation-t143ak{from{rotate:none;}to{rotate:45deg;}}@keyframes animation-t143ak{from{rotate:none;}to{rotate:45deg;}}@-webkit-keyframes animation-1p4nzih{from{rotate:45deg;}to{rotate:0;}}@keyframes animation-1p4nzih{from{rotate:45deg;}to{rotate:0;}}.css-v5yzal{font-size:16px;font-weight:600;text-align:center;margin:0 auto 20px;}.css-v5yzal:active,.css-v5yzal:hover:not(:focus){outline:none;}@media max-mobile{.css-v5yzal{display:block;font-size:14px;padding:9px 18px 10px 16px;width:210px;color:white;background:theme.colors.magenta;padding:0;line-height:50px;height:50px;}.css-v5yzal:hover{color:white;background:#9b1561;}}</style><script src="https://cdn.cookielaw.org/scripttemplates/gpp.stub.js" type="text/javascript"></script><script src="https://cdn.cookielaw.org/scripttemplates/otSDKStub.js" type="text/javascript" data-domain-script="6a2124b1-8744-4206-802a-a322e8a028c3"></script><script> let newDate = new Date(); newDate.setTime(newDate.getTime() + 1 * 3600 * 1000 * 24 * 365); function delete_cookie() { if (!getOTCookie('cleared-onetrust-cookies')) { console.log("Deleting Cookies: OptanonAlertBoxClosed, OTGPPConsent, OptanonConsent"); document.cookie = "OptanonAlertBoxClosed=;path=/;domain=.www.healthline.com;expires=Thu, 01 Jan 1970 00:00:01 GMT'"; document.cookie = "OTGPPConsent=;path=/;domain=.www.healthline.com;expires=Thu, 01 Jan 1970 00:00:01 GMT"; document.cookie = "OptanonConsent=;path=/;domain=.www.healthline.com;expires=Thu, 01 Jan 1970 00:00:01 GMT"; } const hostname = window.location.hostname .split('.') .slice(-2) .join('.'); document.cookie = "cleared-onetrust-cookies=;path=/;domain=" + hostname + ";expires=" + newDate; } function getOTCookie(cookieName) { var value = '; ' + document.cookie; var parts = value.split('; ' + cookieName + '='); if (parts.length == 2) { return true; } } delete_cookie(); </script><script> (function (){window.dataLayer = window.dataLayer || [];})() </script><script> (function (w, d, s, l, i) { w[l] = w[l] || []; w[l].push({ "gtm.start": new Date().getTime(), event: "gtm.js" }); var f = d.getElementsByTagName(s)[0], j = d.createElement(s), dl = l != "dataLayer" ? "&l=" + l : ""; j.async = true; j.src = "https://gtm-server.healthline.com/gtm.js?id=" + i + dl; f.parentNode.insertBefore(j, f); })(window, document, "script", "dataLayer", "GTM-MB6365D"); </script><script> (function () {window.dataLayer.push({event: "ABConfig received", "ABConfig": {"enableDatadogRUM":false,"scrollIndicator":false,"prerollAdRule":false,"postrollAdRule":false,"activationReadNext":true,"adbDlbFix":false,"livedExperienceMVP":false,"expandedTableOfContents":false,"collapsedTableOfContents":false,"experimentalRPM":"variant","adbridgFlag":false,"jwPlayerFix":true,"dcsCopayBestOffer":"control","dcsNativeCoupon":"control","dcsCopayOnly":"variant","reducedFontSize":false,"moveImageGalleryBelowH2":false,"affiliateDisclaimer":false,"affiliateDisclaimer2":false,"adBlockerDetection":false,"contentClusterInfiniteScroll":false,"oneTrustCPRA":true,"pathingTest":true,"moveImageGalleryBelowDeck":"control","apscustomRemoval":false,"showClusterNavMenu":true,"showReferenceJumpLink":"control","showNonCostJumpLink":"control","traveler":"variant"}})})() </script><script> (function () {window.dataLayer.push({event: "Tenant Received", "Tenant": "hl"})})() </script><script> (function () {window.dataLayer.push({event: "TLDDomain Received", "TLDDomain": "healthline.com"})})() </script><script> (function () {window.dataLayer.push({event: "appState Received", "appState": {"title":"Endocannabinoid System: A Simple Guide to How It Works","canonical":"https://www.healthline.com/health/endocannabinoid-system","hrlContentId":"wp-96687","isArticle":true,"isContentSeries":false,"canonicalPath":"/health/endocannabinoid-system","pageTemplate":"Tabbed Article","logMoreMetrics":true,"adsSponsored":false,"isCPUV":false,"newsletter":{"tags":"","categories":"uncategorized"},"isSponsoredArticle":false,"targeting":{"k1":"marijuanause","k2":"substanceuse","k3":"health","kmeta":"eczema-predictive-aq,nsclc-predictive-aq,obesity-predictive-aq,bipolar-predictive-aq-1,bipolar-predictive-aq,vraylar24bp","msiteactive":"false","url":"/health/endocannabinoid-system","articleId":"wp-96687","adLayout":"MEDIUM_DRIVER"},"categories":[{"name":"Uncategorized","slug":"uncategorized","link":"/uncategorized","children":[]}],"subcategories":[],"sponsoredNavMenu":false,"author":"Crystal Raypole","editor":"Judy Lee","contentForm":"Non-Head Term","type":"healthfeature","vertical":"VMS","trackingTerms":[],"isPremiumVideo":false,"isStandaloneVideo":false,"isStandaloneRecipe":false,"isNewsArticle":false,"hasEmbeddedJWPlayer":false,"pageHasDasPreroll":true,"byline":{"authors":[{"id":211,"name":{"display":"Crystal Raypole","first":"Crystal","last":"Raypole"},"link":"/authors/crystal-raypole","type":{"value":"author","label":"Author"},"nid":"","specialties":[],"guestTitle":"","bio":{"text":"<p>Crystal Raypole’s work appears on Healthline, and she’s previously worked as a writer and editor for GoodTherapy. Her interests include Japanese language and translation, cooking, natural sciences, sex positivity, and mental health. In particular, she’s committed to helping decrease stigma around mental health issues. She hopes to someday write fiction — if she can stop reading fiction long enough to write more than a few chapters of anything.</p>\n"},"avatar":{"title":"","width":200,"height":200,"src":"https://post.healthline.com/wp-content/uploads/2020/01/200x200_Crystal_Raypole.png"}}],"medicalReviewers":[{"id":115,"name":{"display":"Alan Carter, Pharm.D.","first":"Alan","last":"Carter, PharmD"},"userLogin":"achealthline","links":{"website":"","facebook":"","linkedin":"https://www.linkedin.com/in/alancarterpharmd/","twitter":"","instagram":"","tiktok":""},"link":"/reviewers/alan-carter-pharmd","type":{"value":"medical_reviewer","label":"Medical Advisor"},"nid":"122506","specialties":[],"guestTitle":"","bio":{"text":"<p style=\"text-align: left;\"><em>This individual is no longer a medical reviewer in our network. The credentials and contact information reflected here may not be current.</em></p>\n<p><span style=\"font-weight: 400;\">Dr. Alan Carter is a clinical pharmacist with interests in medical research, pharmacy practice, and medication formulary management. He is an independent contracted medical director for pharmaceutical development, clinical pharmacy specialist, and adjunct clinical assistant professor of pharmacy.</span></p>\n<p><strong>Education</strong></p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">University of Missouri – Kansas City, BS, PharmD</span></li>\n</ul>\n<p><strong>Certifications</strong></p>\n<ul>\n<li aria-level=\"1\">Licensed Pharmacist</li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Kansas Board of Pharmacy</span></li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Missouri Board of Pharmacy</span></li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Certified Immunizing Pharmacist</span></li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Certified Smoking Cessation Specialist</span></li>\n</ul>\n<p><strong>Professional Accomplishments</strong></p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Published 20 journal articles to date, performs medical journal peer review, and serves on many professional committees and boards</span></li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Awarded the Pharmacy Career Achievement Award by the University of Missouri – Kansas City, 2019</span></li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Served as principal investigator for the National Institutes of Health, NINDS BRAIN Initiative for Neurological Drug Development, 2015-2018</span></li>\n</ul>\n<p><strong>Affiliations</strong></p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https://pharmacy.umkc.edu/\"><span style=\"font-weight: 400;\">University of Missouri-Kansas City School of Pharmacy</span></a></li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https://www.philambdasigma.org/\"><span style=\"font-weight: 400;\">Phi Lambda Sigma Pharmacy Leadership Society</span></a></li>\n</ul>\n"},"avatar":{"title":"","width":500,"height":500,"src":"https://post.healthline.com/wp-content/uploads/2022/01/Alan-Carter-500x500-Bio.png"}}],"id":"wp-96687","updateReason":[],"editor":"Judy Lee","factCheckedBy":"","factCheckers":[],"articleHistory":{"2019-05-17":{"updateReason":[],"authors":"Crystal Raypole","editor":"Judy Lee","medicallyReviewedBy":"Alan Carter, PharmD"}},"articleDates":{"factChecked":{"date":null,"display":""},"medicallyReviewed":{"date":1558101793,"display":"May 17, 2019"},"published":{"date":1558101793,"display":"May 17, 2019"},"lastUpdates":{"date":1558101793,"display":"May 17, 2019"},"modified":{"date":1712068789,"display":"April 2, 2024"}},"type":"healthfeature","language":"en"},"cesData":{"metaDescription":"The endocannabinoid is a complex system that still isn't fully understood. We'll go over what experts do know about it, including how it works, the ways it interacts with cannabis, and theories about its role in different conditions.","title":"Endocannabinoid System: A Simple Guide to How It Works","iab_tag_tier_1":[],"iab_tag_tier_2":[],"mpdTags":[{"confidence":0.9860379591745897,"type":"topic_level_1","value":"health"},{"confidence":0.6421368658185361,"type":"topic_level_2","value":"neurology"},{"confidence":0.8551967451922423,"type":"topic_level_3","value":"cannabis"},{"confidence":0.12152074876798367,"type":"topic_level_4","value":"cbd"},{"confidence":0.7030395102905068,"type":"entity","value":"ec"}]},"relatedStories":false,"wellness":{"title":"wellness reads","coverImageUrl":"/hlcmsresource/images/frontend-static/sidebar-wellness/7354-wellness_reads_option2_600x260-rightrail.jpg","items":[{"title":{"text":"10 Exercises to Tone Every Inch of Your Body","matches":"Tone Every Inch"},"url":"/health/fitness-exercise/10-best-exercises-everyday","thumbnail":"https://media.post.rvohealth.io/wp-content/uploads/2020/07/7040-hispanic_female_exercise-732x549-thumbnail-732x549.jpg"},{"title":{"text":"For a Longer Life and Happier Gut, Eat More Fiber","matches":"Longer Life"},"url":"/health/food-nutrition/fiber-diet-good-for-gut-and-health","thumbnail":"https://media.post.rvohealth.io/wp-content/uploads/2018/01/oatmeal-granola-berries-fiber-732x549-thumbnail-732x549.jpg"},{"title":{"text":"What You Need to Know About the Health Benefits of Collagen","matches":"Collagen"},"url":"/nutrition/collagen-benefits","thumbnail":"https://media.post.rvohealth.io/wp-content/uploads/2020/02/mirror-beauty-skin-732x549-thumbnail-732x549.jpg"},{"title":{"text":"6 Ways to Boost Your Coffee with Vitamins and Antioxidants","matches":"Boost Your Coffee"},"url":"/health/food-nutrition/vitamin-coffee-natural-boost","thumbnail":"https://media.post.rvohealth.io/wp-content/uploads/2020/08/Hands_Coffee_Cinnamon_732x549-thumbnail-732x549.jpg"},{"title":{"text":"The 3-Day Fix for Energy","matches":"3-Day Fix"},"url":"/health/healthy-sleep/guide-fix-fatigue-and-sleepiness","thumbnail":"https://media.post.rvohealth.io/wp-content/uploads/2018/03/male-walking-outdoors-poc-happy-732x549-thumbnail-732x549.jpg"}]},"shouldLoadSEOClarity":false,"shouldLoadFullStory":false,"infiniteScroll":true,"infScrollArticles":[{"title":["The Definitive Guide to Yoga"],"text":["Whether you're a beginner or advanced yogi, here's our thorough guide to achieving a successful practice. Get expert advice, meditation tips, and more."],"link":"/health/fitness-exercise/definitive-guide-to-yoga","imageAlt":"The Definitive Guide to Yoga","thumbnail":"https://media.post.rvohealth.io/wp-content/uploads/2020/08/Yoga_Tablet_Home_Female-732x549-Thumbnail-732x549.jpg","medicallyReviewedBy":{"reviewerName":"Daniel Bubnis, M.S., NASM-CPT, NASE Level II-CSS","reviewerImage":{"path":"https://media.post.rvohealth.io/wp-content/uploads/2022/01/Daniel-Bubnis-500x500-Bio.png","width":200,"height":200,"altText":""},"specialties":["fitness"]},"isNutrition":false,"authors":[{"id":3711,"name":{"display":"Tiffany Cruikshank from Yoga Medicine","first":"tiffany","last":"cruikshank"},"userLogin":"tcruikshank","links":{"website":"","facebook":"","linkedin":"","twitter":"","instagram":"","tiktok":""},"type":{"value":"","label":""},"specialties":[],"bio":{},"avatar":{"title":"","src":""}}],"reviewedByHeader":"Medically reviewed by"},{"title":["Cannabis Got You Paranoid? How to Deal With It"],"text":["Paranoia is one of the less desirable effects that marijuana has on some people. Learn why it happens, who's more likely to experience it, and how to…"],"link":"/health/marijuana-paranoia","imageAlt":"Cannabis Got You Paranoid? How to Deal With It","thumbnail":"https://media.post.rvohealth.io/wp-content/uploads/2020/01/woman-home-eyes-closed-headphones-relaxing-732x549-thumbnail-732x549.jpg","medicallyReviewedBy":{"reviewerName":"Debra Sullivan, Ph.D., MSN, R.N., CNE, COI","reviewerImage":{"path":"https://media.post.rvohealth.io/wp-content/uploads/2022/01/Debra-Sullivan-500x500-Bio.png","width":200,"height":200,"altText":""}},"isNutrition":false,"authors":[{"id":211,"name":{"display":"Crystal Raypole","first":"Crystal","last":"Raypole"},"userLogin":"raypolecrystal","links":{"website":"","facebook":"","linkedin":"","twitter":"","instagram":"","tiktok":""},"link":"/authors/crystal-raypole","type":{"value":"author","label":"Author"},"nid":"","specialties":[],"guestTitle":"","bio":{"text":"<p>Crystal Raypole’s work appears on Healthline, and she’s previously worked as a writer and editor for GoodTherapy. Her interests include Japanese language and translation, cooking, natural sciences, sex positivity, and mental health. In particular, she’s committed to helping decrease stigma around mental health issues. She hopes to someday write fiction — if she can stop reading fiction long enough to write more than a few chapters of anything.</p>\n"},"avatar":{"title":"","width":200,"height":200,"src":"https://post.healthline.com/wp-content/uploads/2020/01/200x200_Crystal_Raypole.png"}}],"reviewedByHeader":"Medically reviewed by"},{"title":["A Quick Take on Cannabis and Its Effects"],"text":["As weed becomes legal in more areas, names for it are evolving. Today, more and more people are using the term cannabis to refer to weed. Read on to…"],"link":"/health/what-is-cannabis","imageAlt":"A Quick Take on Cannabis and Its Effects","thumbnail":"https://media.post.rvohealth.io/wp-content/uploads/2020/07/10269-What_Is_Cannabis-_Facts_About_Its_Components_Effects_and_Hazards_732x549-thumbnail-732x549.jpg","medicallyReviewedBy":{"reviewerName":"Femi Aremu, PharmD","reviewerImage":{"path":"https://media.post.rvohealth.io/wp-content/uploads/2022/01/Femi-Aremu-500x500-Bio.png","width":200,"height":200,"altText":""},"specialties":[]},"isNutrition":false,"authors":[{"id":49,"name":{"display":"Kimberly Holland","first":"Kimberly","last":"Holland"},"userLogin":"kimholland","links":{"website":"","facebook":"","linkedin":"","twitter":"","instagram":"https://www.instagram.com/khollandcooks/?hl=en","tiktok":""},"link":"/authors/kimberly-holland","type":{"value":"author","label":"Author"},"nid":"159200","specialties":[],"guestTitle":"","bio":{"text":"<p>Kimberly is a freelance health, travel, and lifestyle writer and editor living in Birmingham, AL. She has previously written for Cooking Light, Eating Well, Coastal Living, Real Simple, Reader’s Digest, and more. When she’s not writing, you’ll likely find her watching “Murder, She Wrote” and sorting her collection of books that she’ll certainly one day find time to read, or planning her next vacation, preferably to an island, please.</p>\n"},"avatar":{"title":"","width":200,"height":200,"src":"https://post.healthline.com/wp-content/uploads/2019/03/200x200_Kimberly_Holland.png"}}],"reviewedByHeader":"Medically reviewed by"},{"title":["Cannabis Withdrawal: What it is and What to Expect"],"text":["It is possible to have cannabis use disorder, and when you stop using it, you can have withdrawal. Learn more. "],"link":"/health/video/marijuana-withdrawal","imageAlt":"Cannabis Withdrawal: What it is and What to Expect","thumbnail":"https://media.post.rvohealth.io/wp-content/uploads/2020/09/2574-Young_man_smoking_Marijuana-732x549-thumbnail-732x549.jpg","medicallyReviewedBy":{"reviewerName":"the Healthline Medical Network","reviewerImage":{"path":"","width":0,"height":0,"altText":false}},"isNutrition":false,"authors":[{"id":6628,"name":{"display":"the Healthline Video Team","first":"the Healthline Video Team","last":""},"userLogin":"hlvideoteam","links":{"website":"","facebook":"","linkedin":"","twitter":"","instagram":"","tiktok":""},"type":{"value":"author","label":"Author"},"nid":"","specialties":[],"guestTitle":"","bio":{"text":""},"avatar":{"title":"","src":""}}],"reviewedByHeader":"Medically reviewed by"},{"title":["As Legal Cannabis Expands, More Kids Are Getting Sick From Edibles"],"text":["U.S. poison control centers recorded more than 7,000 cases of children 6 and under who consumed cannabis edibles from 2017 to 2021, according to a new…"],"link":"/health-news/more-kids-getting-sick-from-edibles-as-legal-cannabis-expands","imageAlt":"As Legal Cannabis Expands, More Kids Are Getting Sick From Edibles","thumbnail":"https://media.post.rvohealth.io/wp-content/uploads/2023/01/child-hand-brownie-732x549-thumbnail-732x549.jpg","isNutrition":false,"authors":[{"id":26,"name":{"display":"Shawn Radcliffe","first":"Shawn","last":"Radcliffe"},"userLogin":"sradcliffe","links":{"website":"","facebook":"","linkedin":"","twitter":"ShawnRadcliffe","instagram":"","tiktok":""},"link":"/authors/shawn-radcliffe","type":{"value":"author","label":"Author"},"nid":"","specialties":[],"guestTitle":"","bio":{"text":"<p><span data-sheets-value=\"{"1":2,"2":"Shawn Radcliffe is a science writer and yoga teacher in Ontario, Canada. His work has appeared in print and digital publications, including Healthline, Mindbodygreen, Science & Nonduality, and others. Originally from New Hampshire, Shawn lived in Philadelphia and Portland, Oregon, before trading in the big city for small-town living. When he’s not reading or writing, Shawn is often backpacking, bicycling, or wandering the streets of a new city. Connect with him on Twitter."}\" data-sheets-userformat=\"{"2":771,"3":{"1":0},"4":[null,2,11982760],"11":3,"12":0}\">Shawn Radcliffe is a science writer and yoga teacher in Ontario, Canada. His work has appeared in print and digital publications, including Healthline, Mindbodygreen, Science & Nonduality, and others. Originally from New Hampshire, Shawn lived in Philadelphia and Portland, Oregon, before trading in the big city for small-town living. When he’s not reading or writing, Shawn is often backpacking, bicycling, or wandering the streets of a new city. Connect with him on <a href=\"https://twitter.com/ShawnRadcliffe\">Twitter</a>.</span></p>\n"},"avatar":{"title":"","width":500,"height":500,"src":"https://post.healthline.com/wp-content/uploads/2020/08/500x500_Shawn_Radcliffe.png"}}],"reviewedByHeader":"Medically reviewed by"},{"title":["Can You Use Weed While You’re Taking Antibiotics?"],"text":["The current research isn't certain whether it could have harmful or beneficial effects. Let's look at what you need to know if you plan on using…"],"link":"/health/antibiotics/antibiotics-and-weed","imageAlt":"Can You Use Weed While You’re Taking Antibiotics?","thumbnail":"https://media.post.rvohealth.io/wp-content/uploads/2022/10/senior_rolling_marijuana_joint-732x549-thumbnail-732x549.jpg","medicallyReviewedBy":{"reviewerName":"Alan Carter, Pharm.D.","reviewerImage":{"path":"https://media.post.rvohealth.io/wp-content/uploads/2022/01/Alan-Carter-500x500-Bio.png","width":200,"height":200,"altText":""}},"isNutrition":false,"authors":[{"id":1554,"name":{"display":"S. Srakocic","first":"S.","last":"Srakocic"},"userLogin":"sbehring","links":{"website":"http://www.srakocicwriting.com/","facebook":"","linkedin":"","twitter":"","instagram":"","tiktok":""},"link":"/authors/s-srakocic","type":{"value":"author","label":"Author"},"nid":"","specialties":[],"guestTitle":"","bio":{"text":"<p>S. Srakocic spent several years working in healthcare before making a major change and shifting to freelance writing. Focusing her writing career on healthcare and education allows her to translate her previous experience and create articles that are both accessible and informative. Her work has appeared in a growing list of publications of all sizes. You can find out more on her <a class=\"PrimaryLink BaseLink\" href=\"http://www.srakocicwriting.com/\" target=\"_blank\" rel=\"noreferrer noopener\">website</a>.</p>\n"},"avatar":{"title":"","width":500,"height":500,"src":"https://post.healthline.com/wp-content/uploads/2021/12/Stephanie-Behring-500x500-Bio.png"}}],"reviewedByHeader":"Medically reviewed by"},{"title":["Cannabis for Chronic Pain Linked to Slightly Increased Risk of Arrhythmia"],"text":["People who use medical cannabis products for chronic pain may have a higher risk of heart rhythm disorders, or arrhythmias, according to preliminary…"],"link":"/health-news/cannabis-for-chronic-pain-linked-to-slightly-increased-risk-of-arrhythmia","imageAlt":"Cannabis for Chronic Pain Linked to Slightly Increased Risk of Arrhythmia","thumbnail":"https://media.post.rvohealth.io/wp-content/uploads/2022/08/cannabis-dispensary-732x549-thumbnail-732x549.jpg","isNutrition":false,"authors":[{"id":26,"name":{"display":"Shawn Radcliffe","first":"Shawn","last":"Radcliffe"},"userLogin":"sradcliffe","links":{"website":"","facebook":"","linkedin":"","twitter":"ShawnRadcliffe","instagram":"","tiktok":""},"link":"/authors/shawn-radcliffe","type":{"value":"author","label":"Author"},"nid":"","specialties":[],"guestTitle":"","bio":{"text":"<p><span data-sheets-value=\"{"1":2,"2":"Shawn Radcliffe is a science writer and yoga teacher in Ontario, Canada. His work has appeared in print and digital publications, including Healthline, Mindbodygreen, Science & Nonduality, and others. Originally from New Hampshire, Shawn lived in Philadelphia and Portland, Oregon, before trading in the big city for small-town living. When he’s not reading or writing, Shawn is often backpacking, bicycling, or wandering the streets of a new city. Connect with him on Twitter."}\" data-sheets-userformat=\"{"2":771,"3":{"1":0},"4":[null,2,11982760],"11":3,"12":0}\">Shawn Radcliffe is a science writer and yoga teacher in Ontario, Canada. His work has appeared in print and digital publications, including Healthline, Mindbodygreen, Science & Nonduality, and others. Originally from New Hampshire, Shawn lived in Philadelphia and Portland, Oregon, before trading in the big city for small-town living. When he’s not reading or writing, Shawn is often backpacking, bicycling, or wandering the streets of a new city. Connect with him on <a href=\"https://twitter.com/ShawnRadcliffe\">Twitter</a>.</span></p>\n"},"avatar":{"title":"","width":500,"height":500,"src":"https://post.healthline.com/wp-content/uploads/2020/08/500x500_Shawn_Radcliffe.png"}}],"reviewedByHeader":"Medically reviewed by"},{"title":["States With Legalized Cannabis Have Fewer Synthetic Cannabinoid Poisonings"],"text":["New research shows a drop in synthetic cannabis poisonings in states that have legalized recreational cannabis. Synthetic cannabis products contain…"],"link":"/health-news/states-with-legalized-cannabis-have-fewer-synthetic-cannabinoid-poisonings","imageAlt":"States With Legalized Cannabis Have Fewer Synthetic Cannabinoid Poisonings","thumbnail":"https://media.post.rvohealth.io/wp-content/uploads/2022/08/cannabis-shop-oregon-732x549-thumbnail-732x549.jpg","isNutrition":false,"authors":[{"id":26,"name":{"display":"Shawn Radcliffe","first":"Shawn","last":"Radcliffe"},"userLogin":"sradcliffe","links":{"website":"","facebook":"","linkedin":"","twitter":"ShawnRadcliffe","instagram":"","tiktok":""},"link":"/authors/shawn-radcliffe","type":{"value":"author","label":"Author"},"nid":"","specialties":[],"guestTitle":"","bio":{"text":"<p><span data-sheets-value=\"{"1":2,"2":"Shawn Radcliffe is a science writer and yoga teacher in Ontario, Canada. His work has appeared in print and digital publications, including Healthline, Mindbodygreen, Science & Nonduality, and others. Originally from New Hampshire, Shawn lived in Philadelphia and Portland, Oregon, before trading in the big city for small-town living. When he’s not reading or writing, Shawn is often backpacking, bicycling, or wandering the streets of a new city. Connect with him on Twitter."}\" data-sheets-userformat=\"{"2":771,"3":{"1":0},"4":[null,2,11982760],"11":3,"12":0}\">Shawn Radcliffe is a science writer and yoga teacher in Ontario, Canada. His work has appeared in print and digital publications, including Healthline, Mindbodygreen, Science & Nonduality, and others. Originally from New Hampshire, Shawn lived in Philadelphia and Portland, Oregon, before trading in the big city for small-town living. When he’s not reading or writing, Shawn is often backpacking, bicycling, or wandering the streets of a new city. Connect with him on <a href=\"https://twitter.com/ShawnRadcliffe\">Twitter</a>.</span></p>\n"},"avatar":{"title":"","width":500,"height":500,"src":"https://post.healthline.com/wp-content/uploads/2020/08/500x500_Shawn_Radcliffe.png"}}],"reviewedByHeader":"Medically reviewed by"}],"hidePlacements":[],"userPreloadDrivers":{"headerNewsletter":{"_driverPath":"/health/endocannabinoid-system","_contentIndex":"page","driverId":"c54448fb-575c-413d-993f-5cf346330a9f","siteId":"3bd23390-7108-11ea-8600-afc672063050","site":"hl","status":"on","deleted":false,"overridePredictiveRPM":false,"created":"2022-12-19T19:59:53.000Z","updated":"2024-11-05T21:03:43.000Z","createdBy":"liallison@redventures.com","updatedBy":"mrobinson@rvohealth.com","isTest":false,"overridePredictiveRPMType":"none","rewardType":"","customModel":false,"holdout":"","sdapiTestName":"","modelType":"","imageMobile":"https://media.post.rvohealth.io/2kLEJX4A3LDe7GGDNr31WST2A26/2024/09/26/2mc75hgmcKGdy2Btow91zCpyUlu.jpeg","color":"#02838d","driverTypeId":"1ed6a315-4241-4254-92ae-17d0570ee038","sailthruAccount":"hl","titleOverride":"The health and wellness newsletter you’ve been looking for ","newsletterSource":"Wellness Wire","id":"3c10d216-ff83-4e7e-8e69-dd0be853dcba","trackingNumber":39699,"adTagIds":["5bfa54a0-cb61-11ea-841d-230b5918b98d"],"articlePlacement":"headerNewsletter","image":"https://healthline-activation-prod.healthline.com/driver-images/Wellness%20Wire%20Relaunch%20-%20Visual%20Driver-732x549-Thumbnail%20(1).jpg","titleOverrideMobile":"The health and wellness newsletter you’ve been looking for ","secondaryNewsletters":[],"descriptionModal":"Interested in exclusive interviews, must-have products, and staying updated with trending news? Wellness Wire has it all, and you don’t want to miss out.","driverType":"headerNewsletter","verticalId":"5474f994-0335-422b-aab5-b87a0410aec6","verticalName":"Wellness Wire","lists":["Wellness Wire"],"name":"lifecycle_header_hl_wewi_newsletter","imageDesktop":"https://healthline-activation-prod.healthline.com/driver-images/Wellness%20Wire%20Relaunch%20-%20Visual%20Driver-700x1076-Desktop%20Driver.jpg","descriptionModalMobile":"Interested in exclusive interviews, must-have products, and staying updated with trending news? Wellness Wire has it all, and you don’t want to miss out.","driverPlacementId":"d5b8e667-55c1-4a6d-b05d-728a1733109b","campaignName":"lifecycle_header_hl_wewi_newsletter_39699","productId":"lifecycle_header_hl_wewi_newsletter_39699","_uuid":"mdf023cc0-853f-415a-9fa6-5455aaf12c12mpd_headerNewsletter_c54448fb-575c-413d-993f-5cf346330a9f","cpm":9.210263698372723e+306}},"travelerDisabledReasons":["User is located outside the US (SG)"]}})})() </script><script> (function () {window.dataLayer.push({event: "GDPR Consent Status Received", "isGdprFullConsentGranted": true})})() </script><script> (function () {window.dataLayer.push({event: "USP Consent Status Received", "hasBlockedTargetingCookies": false})})() </script><meta content="width=device-width, initial-scale=1, minimum-scale=1" name="viewport"/><meta charSet="utf-8"/><meta name="robots" content="max-image-preview:large"/><link rel="preload" href="https://assets.healthline.com/fonts/proxima/v1/32A982_7_0.woff2" as="font" type="font/woff2" crossorigin="anonymous"/><link rel="preload" href="https://assets.healthline.com/fonts/proxima/v1/32A982_9_0.woff2" as="font" type="font/woff2" crossorigin="anonymous"/><link rel="preload" href="https://assets.healthline.com/fonts/proxima/v1/38C507_0_0.woff2" as="font" type="font/woff2" crossorigin="anonymous"/><link href="https://images-prod.healthline.com/hlcmsresource/images/frontend-static/favicon/v1/apple-touch-icon.png" rel="apple-touch-icon" sizes="180x180"/><link rel="shortcut icon" href="https://images-prod.healthline.com/hlcmsresource/images/frontend-static/favicon/hl-logo-logomark-circle-black.ico"/><link href="https://securepubads.g.doubleclick.net" rel="preconnect" crossorigin="true"/><link href="https://ib.adnxs.com" rel="preconnect" crossorigin="true"/><link href="https://prebid.media.net" rel="preconnect" crossorigin="true"/><link href="https://tlx.3lift.com" rel="preconnect" crossorigin="true"/><link href="https://static.chartbeat.com" rel="preconnect" crossorigin="true"/><link href="https://adserver-us.adtech.advertising.com" rel="preconnect" crossorigin="true"/><style>@keyframes animation-b7n1on{0%{transform:rotate(0deg)}100%{transform:rotate(360deg)}}hr{box-sizing:content-box;height:0;overflow:visible}pre{font-family:monospace,monospace;font-size:1em}a{background-color:transparent;-webkit-text-decoration-skip:objects}a:active,a:hover{outline-width:0}abbr[title]{border-bottom:none;text-decoration:underline;text-decoration:underline dotted}b,strong{font-weight:inherit}b,strong{font-weight:bolder}code,kbd,samp{font-family:monospace,monospace;font-size:1em}dfn{font-style:italic}small{font-size:80%}sub,sup{font-size:75%;line-height:0;position:relative;vertical-align:baseline}sub{bottom:-0.25em}sup{top:-0.5em}audio:not([controls]){display:none;height:0}svg:not(:root){overflow:hidden}button,input,optgroup,select,textarea{font-family:sans-serif;font-size:100%;line-height:1.15;margin:0}button,input{overflow:visible}button,select{text-transform:none}button,html [type="button"],[type="reset"],[type="submit"]{-webkit-appearance:button}button::-moz-focus-inner,[type="button"]::-moz-focus-inner,[type="reset"]::-moz-focus-inner,[type="submit"]::-moz-focus-inner{border-style:none;padding:0}button:-moz-focusring,[type="button"]:-moz-focusring,[type="reset"]:-moz-focusring,[type="submit"]:-moz-focusring{outline:1px dotted ButtonText}fieldset{border:1px solid #c0c0c0;margin:0 2px;padding:0.35em 0.625em 0.75em}legend{box-sizing:border-box;color:inherit;display:table;max-width:100%;padding:0;white-space:normal}progress{display:inline-block;vertical-align:baseline}textarea{overflow:auto}[type=checkbox],[type=radio]{box-sizing:border-box;padding:0}[type="number"]::-webkit-inner-spin-button,[type="number"]::-webkit-outer-spin-button{height:auto}[type="search"]{-webkit-appearance:textfield;outline-offset:-2px}[type="search"]::-webkit-search-cancel-button,[type="search"]::-webkit-search-decoration{-webkit-appearance:none}::-webkit-file-upload-button{-webkit-appearance:button;font:inherit}details,menu{display:block}summary{display:list-item}@font-face{font-family:'Proxima Nova';font-style:normal;font-weight:400;font-display:swap;src:local('☺︎'),url('https://assets.healthline.com/fonts/proxima/v1/32A982_7_0.woff2') format('woff2'),url('https://assets.healthline.com/fonts/proxima/v1/32A982_7_0.woff') format('woff')}@font-face{font-family:'Proxima Nova';font-style:normal;font-weight:600;font-display:swap;src:local('☺︎'),url('https://assets.healthline.com/fonts/proxima/v1/32A982_9_0.woff2') format('woff2'),url('https://assets.healthline.com/fonts/proxima/v1/32A982_9_0.woff') format('woff')}@font-face{font-family:'Proxima Nova';font-style:normal;font-weight:700;font-display:swap;src:local('☺︎'),url('https://assets.healthline.com/fonts/proxima/v1/32A982_1_0.woff2') format('woff2'),url('https://assets.healthline.com/fonts/proxima/v1/32A982_1_0.woff') format('woff')}@font-face{font-family:'Proxima Nova Fallback';src:local('Arial');size-adjust:99%;ascent-override:80%}@font-face{font-family:'Proxima Nova Condensed';font-style:normal;font-weight:700;font-display:swap;src:local('☺︎'),url('https://assets.healthline.com/fonts/proxima/v1/38C507_0_0.woff2') format('woff2'),url('https://assets.healthline.com/fonts/proxima/v1/38C507_0_0.woff') format('woff')}@font-face{font-family:'Proxima Nova Condensed Fallback';src:local('Arial Narrow');size-adjust:109%;ascent-override:80%}*{-moz-osx-font-smoothing:grayscale;-webkit-font-smoothing:antialiased}*,*:before,*:after{box-sizing:inherit}:-moz-ui-invalid{box-shadow:none}html{box-sizing:border-box;text-size-adjust:100%;cursor:default;font-size:17px;line-height:1.15;-webkit-text-size-adjust:100%;font-family:"Proxima Nova","Proxima Nova Fallback",sans-serif;color:#231f20}html,body{height:100%;width:100%;margin:0;overflow-anchor:auto}.sro{position:absolute;left:-10000px;top:auto;width:1px;height:1px;overflow:hidden}button{font-family:inherit;font-size:14px;line-height:16px}cite{font-style:inherit}figure{margin:0}form{margin-bottom:0;margin-top:0}h1,.h1{font-family:"Proxima Nova Condensed","Proxima Nova Condensed Fallback",sans-serif;font-weight:700;font-size:34px;line-height:38px;margin-bottom:15px;margin-top:25px}h2,.h2{font-weight:bold;position:relative;clear:both;font-family:"Proxima Nova","Proxima Nova Fallback",sans-serif;font-weight:bold;font-size:24px;line-height:30px;margin-bottom:15px;margin-top:30px}h3,.h3{font-weight:bold;clear:both;font-family:"Proxima Nova","Proxima Nova Fallback",sans-serif;font-weight:bold;font-size:20px;line-height:26px;margin-bottom:15px;margin-top:30px}h4{font-weight:bold;font-size:17px;line-height:26px;margin-bottom:15px;margin-top:20px;font-family:"Proxima Nova","Proxima Nova Fallback",sans-serif;font-weight:bold;font-size:18px;line-height:26px;margin-bottom:15px;margin-top:20px}hr{border:none;border-top:1px solid #dcdbdb;line-height:0;margin-bottom:20px;margin-top:30px}img{-webkit-user-select:none;-moz-user-select:none;user-select:none;max-width:100%}iframe{max-width:100%}li{font-size:17px;line-height:26px;margin-bottom:8px}ol.hl-long-line > li,ul.hl-long-line > li{margin-bottom:15px}p,.p{margin-bottom:20px;margin-top:20px;font-size:17px;line-height:26px}ul{list-style-image:url("data:image/svg+xml,%3Csvg width='10' height='10' xmlns='http://www.w3.org/2000/svg'%3E%3Ccircle cx='5' cy='5' r='2.5' fill='%23EC1C82'/%3E%3C/svg%3E")}ul li > ul{list-style-image:url("data:image/svg+xml,%3Csvg width='10' height='10' xmlns='http://www.w3.org/2000/svg'%3E%3Ccircle cx='5' cy='5' r='2.5' fill='%23FFF' stroke='%23EC1C82'/%3E%3C/svg%3E")}small{font-size:14px;line-height:20px}table{border-collapse:collapse;font-size:16px;line-height:24px}.__chrome{display:flex;flex-direction:column;min-height:100%}#__next{flex-grow:1}body:not(.user-is-tabbing) :focus{outline:none}body .aa-Panel{z-index:500}@font-face{font-family:'healthline';font-display:swap;src:local('☺︎'),url('https://assets.healthline.com/_next/_static/nku3xo2nmvjomg==.woff') format('woff')}@font-face{font-family:'healthline-video';font-display:swap;src:local('☺︎'),url('https://assets.healthline.com/_next/_static/mhze5frbrsgdxw==.woff') format('woff')}@font-face{font-family:'healthline-video-mobile';font-display:swap;src:local('☺︎'),url('https://assets.healthline.com/_next/_static/bwpcf/z3fqxyxg==.woff') format('woff')}[class*="icon-hl"]::before,[class*="icon-hl"]::after{font-family:"healthline";font-style:normal;font-weight:normal;font-variant:normal;text-transform:none;speak:none;line-height:1}[class*="icon-hlvideo-"]::before{font-family:"healthline-video"}[class*="icon-hlvideo-mobile-"]::before{font-family:"healthline-video-mobile"}.icon-hl-arrow-right::before{content:''}.icon-hl-circle-arrow::before{content:''}.icon-hl-circle-arrow-bold::before{content:''}.icon-hl-arrow-right-bold::before{content:''}.icon-hl-check::before{content:'u'}.icon-hl-check-thin::before{content:'p'}.icon-hl-chevron-left::before{content:''}.icon-hl-chevron-right::before{content:''}.icon-hl-circle-alert::before{content:'b'}.icon-hl-circle-heart::before{content:'t'}.icon-hl-circle-question::before{content:'q'}.icon-hl-circle-thumb-down::before{content:'r'}.icon-hl-circle-thumb-up::before{content:'s'}.icon-hl-close::before{content:'h'}.icon-hl-close-thick::before{content:''}.icon-hl-close-thin::before{content:'x'}.icon-hl-email::before{content:''}.icon-hl-facebook::before{content:'v'}.icon-hl-frown::before{content:''}.icon-hl-gallery::before{content:'y'}.icon-hl-logo-icon::before{content:'m'}.icon-hl-more::before{content:''}.icon-hl-instagram::before{content:''}.icon-hl-pinterest::before{content:'z'}.icon-hl-print::before{content:''}.icon-hl-reddit::before{content:''}.icon-hl-smile::before{content:''}.icon-hl-twitter::before{content:''}.icon-hl-flipboard::before{content:''}.icon-hl-sms::before{content:'{'}.icon-hl-trusted-source::before{content:''}.icon-hl-new-logo-icon::before{content:''}.icon-hl-ribbon::before{content:''}.icon-hl-star::before{content:''}.icon-hl-outbound-link::before{content:''}.icon-hl-linkedin::before{content:''}.icon-hl-youtube-new::before{content:''}.icon-hl-trusted-source-after::after{content:''}.icon-hl-ribbon-after::after{content:''}.icon-hlvideo-play-circle-after::after{content:''}.icon-hlvideo-back-10::before{content:''}.icon-hlvideo-minus::before{content:''}.icon-hlvideo-pause::before{content:''}.icon-hlvideo-play-circle::before{content:''}.icon-hlvideo-play-square::before{content:''}.icon-hlvideo-play::before{content:''}.icon-hlvideo-plus::before{content:''}.icon-hlvideo-replay::before{content:''}.icon-hlvideo-mobile-close::before{content:''}.icon-hlvideo-mobile-expand::before{content:''}.icon-hlvideo-mobile-loading::before{content:''}.icon-hlvideo-mobile-mute::before{content:''}.icon-hlvideo-mobile-pause::before{content:''}.icon-hlvideo-mobile-play::before{content:''}.icon-hlvideo-mobile-replay::before{content:''}.icon-hlvideo-mobile-unmute::before{content:''}@keyframes animation-hh42uh{0%{opacity:0;transform:translateY(-15%)}100%{opacity:1;transform:translateY(0)}}.QSIEmbeddedTarget div:first-child{border:0 !important}.QSIEmbeddedTarget img[alt="Close"]{top:0 !important;right:0 !important;padding:12px}.css-w2pt6r{font-size:22px;line-height:30px;margin:20px 0}.css-1c2ok3c{cursor:pointer;text-decoration:none;border-color:currentColor;color:#02838d}.css-1c2ok3c:hover{color:#08565c}.css-1c2ok3c:hover img,.css-1c2ok3c:hover .image{opacity:0.8}.css-1c2ok3c:hover svg{fill:currentColor}.css-1c2ok3c:active{color:#9b1561}.css-j5n0jw{cursor:pointer;text-decoration:none;border-color:currentColor;color:#02838d;color:inherit}.css-j5n0jw:hover{color:#08565c}.css-j5n0jw:hover img,.css-j5n0jw:hover .image{opacity:0.8}.css-j5n0jw:hover svg{fill:currentColor}.css-j5n0jw:active{color:#9b1561}.css-a10gts{display:flex;flex-direction:row;align-items:center;position:absolute;bottom:0;right:0}.css-17ztj4b{display:flex;flex-wrap:wrap;list-style:none;margin:0;margin-left:-12px;padding:0}.css-t753mo{white-space:nowrap;font-size:16px;line-height:20px;margin:0;padding:0;position:relative;color:blue}.css-t753mo:after{content:"";background:#bcbfc5;position:absolute;top:2px;right:-1px;bottom:0;height:16px;width:1px;margin:auto}.css-t753mo:last-child:after{content:none}.css-1r1p1p8{cursor:pointer;text-decoration:none;border-color:currentColor;color:#02838d;font-size:16px;line-height:28px;padding:0 12px}.css-1r1p1p8:hover{color:#08565c}.css-1r1p1p8:hover img,.css-1r1p1p8:hover .image{opacity:0.8}.css-1r1p1p8:hover svg{fill:currentColor}.css-1r1p1p8:active{color:#9b1561}.css-d2znx6{margin-bottom:25px}.css-12weawj{display:flex;list-style:none;margin-bottom:40px}.css-12weawj:last-child{margin-bottom:0}.css-12weawj:last-child .css-vr2som::after{display:none}.css-f0t0lw{flex:none;margin:0 0 20px}.css-1l95nvm{margin:0;padding:0}.css-zya54r{display:block;min-height:0px}.css-1m3pkrv{position:relative;z-index:500;background-color:#231f20;color:white}.css-m260rd{margin-left:auto;margin-right:auto;max-width:550px;width:calc(100vw - 40px)}.css-tqpz90{display:flex;align-items:center;justify-content:space-between;height:50px}.css-tqpz90 .logo{fill:white}.css-1w3ble7{display:flex;flex:0 0 75px}.css-cs3emt{display:flex;margin-right:14px}.css-x4xfyn{width:22px;height:14px;position:relative;background-color:transparent;border:none;height:14px;width:25px}.css-qzkqso{display:block;position:absolute;height:3px;width:100%;background:white;border-radius:3px;opacity:1;left:0;background-color:white;height:3px;top:0;width:100%}.css-wyg90z{display:block;position:absolute;height:3px;width:100%;background:white;border-radius:3px;opacity:1;left:0;background-color:white;height:3px;top:50%}.css-m8s3k4{display:block;position:absolute;height:3px;width:100%;background:white;border-radius:3px;opacity:1;left:0;background-color:white;height:3px;top:100%;width:100%}.css-10aca47{display:flex}.css-18bsjiu{margin-top:1px;height:16px;fill:white;z-index:10;transition:fill 0.2s}.css-1g6cesj{display:flex}.css-12mc611{width:138px;height:22px;display:flex;align-items:center;justify-content:center}.css-1bqkt1y{cursor:pointer;text-decoration:none;color:inherit;width:138px;height:22px;display:flex;width:100%;align-items:center}.css-yc5e1l{min-height:22px}.css-1wyiq3l{display:none;flex:1 0 auto}.css-yer60s{font-family:"Proxima Nova","Proxima Nova Fallback",sans-serif;font-weight:bold;text-transform:uppercase;margin-top:0;transition:color 0.2s;color:#231f20;line-height:1}.css-ajcamw{font-size:20px;height:20px;margin-left:8px;margin-top:0;color:#231f20}.css-dke6ht{cursor:pointer;text-decoration:none;border-color:currentColor;color:#02838d;text-decoration:none;display:flex;align-items:center;margin-left:8px}.css-dke6ht:hover{color:#08565c}.css-dke6ht:hover img,.css-dke6ht:hover .image{opacity:0.8}.css-dke6ht:hover svg{fill:currentColor}.css-dke6ht:active{color:#9b1561}.css-16uojuo{transition:opacity .2s;max-height:70px;max-width:70px}.css-10adefi{flex-direction:row;display:flex;align-items:center;justify-content:space-between}.css-1n6ef6i{height:70px;width:70px;overflow:hidden;margin-right:20px;min-width:70px}.css-1wtf0mw{font-weight:600;font-size:18px;line-height:22px;margin-top:0;margin-bottom:0;flex:1;display:flex;flex-direction:row;justify-content:space-between}.css-8sow18{font-size:14px;line-height:20px}.css-1q1spi4{transition:opacity .2s;max-height:70px;max-width:70px}.css-1dm1ger{height:70px;width:70px;overflow:hidden;margin-right:15px;min-width:70px}.css-bbu8su{font-weight:600;font-size:17px;line-height:23px;margin-top:0;margin-bottom:0;flex:1;display:flex;flex-direction:row;justify-content:space-between}.css-1bdb0zy{padding-top:20px;border-top-width:0;border-top-color:#767474;border-top-style:solid}.css-1bdb0zy a{width:24px;height:24px;margin-left:0;margin-right:35px}.css-1bdb0zy a::before{font-size:24px;line-height:24px;text-align:center}.css-lembgb{cursor:pointer;text-decoration:none;border-color:currentColor;color:#02838d;display:inline-flex;text-decoration:none;width:20px;height:20px;color:#231f20;margin-right:15px;margin-left:10px}.css-lembgb:hover{color:#08565c}.css-lembgb:hover img,.css-lembgb:hover .image{opacity:0.8}.css-lembgb:hover svg{fill:currentColor}.css-lembgb:active{color:#9b1561}.css-lembgb::before{font-size:20px}.css-lembgb:last-child{margin-right:0}.css-1a25cod{background-color:#dcdbdb;height:40px;margin-right:12px;width:1px;display:none}.css-v5umvf{font-family:"Proxima Nova Condensed","Proxima Nova Condensed Fallback",sans-serif;font-weight:700;padding:0;cursor:pointer;-webkit-appearance:none;-moz-appearance:none;appearance:none;background:none;border:none;color:#02838d;font-size:12px;text-transform:uppercase}.css-v5umvf:hover{color:#08565c}.css-1ur4f3m{background-color:#dcdbdb;height:40px;margin-left:12px;width:1px;display:none}.css-2dofw9{position:relative;display:none;align-items:center;min-width:40px;order:4}.css-2dofw9 svg{height:16px}.css-ifmqwy{position:relative;left:0;width:100%}.css-1wm8u43{position:fixed;z-index:1;top:0;left:0;right:0;opacity:1;transition:none;position:static;display:none;align-items:center;justify-content:center;height:130px;z-index:300;margin:0;padding-top:0;background:#f7f7f7;border-bottom:none;pointer-events:all}.css-1hjaa0k{position:fixed}.css-1jpwf16{display:block;justify-content:center}.css-1j2d96m{z-index:0;clear:both;position:relative;text-align:center}.css-1j2d96m::before{content:'ADVERTISEMENT';display:block;position:absolute;top:-20px;left:0;right:0;height:20px;font-size:9px;line-height:20px;-webkit-letter-spacing:1px;-moz-letter-spacing:1px;letter-spacing:1px;color:#bcbfc5}.css-1j2d96m:empty::before{display:none}.css-1j2d96m::before{text-align:center}.css-1j2d96m.css-1j2d96m{width:unset}.css-11egx89{align-items:flex-end;background:white;display:flex;justify-content:center;height:auto;padding-top:14px}.css-pdceuf{position:fixed;bottom:0;left:0;right:0;z-index:300}.css-16m9poz{cursor:pointer;text-decoration:none;border-color:currentColor;color:#02838d;color:inherit;font-size:14px;line-height:16px;background:transparent;border-radius:1px;border-width:0;color:#231f20;padding:0;-webkit-user-select:none;-moz-user-select:none;user-select:none;position:absolute;right:0;top:-15px;width:30px;height:30px;border-radius:100%;color:#767474;background:white;z-index:1;font-size:13px}.css-16m9poz:hover{color:#08565c}.css-16m9poz:hover img,.css-16m9poz:hover .image{opacity:0.8}.css-16m9poz:hover svg{fill:currentColor}.css-16m9poz:active{color:#9b1561}.css-16m9poz:active,.css-16m9poz:hover:not(:focus){outline:none}.css-16m9poz:active{color:#ec1d8f}.css-16m9poz::before{position:absolute;top:0;right:0;bottom:0;left:0;line-height:30px;text-align:center}.css-bcus5s{display:block;justify-content:center;min-height:50px;width:320px}.css-1fteite{z-index:0;clear:both;position:relative;text-align:center;display:block;min-height:50px;width:320px;padding-bottom:6px;z-index:1;height:auto}.css-1fteite::before{content:'ADVERTISEMENT';display:block;position:absolute;top:-20px;left:0;right:0;height:20px;font-size:9px;line-height:20px;-webkit-letter-spacing:1px;-moz-letter-spacing:1px;letter-spacing:1px;color:#bcbfc5}.css-1fteite:empty::before{display:none}.css-1fteite::before{pointer-events:none;line-height:9px;text-align:left;height:auto;max-width:330px;padding:0 5px;top:-10px;right:0;left:0;margin:auto}.css-1h1rean{display:block;justify-content:space-between;width:100%}.css-blwnmv{display:block;justify-content:space-between;width:100%;margin-bottom:40px}.css-blwnmv article > h2:first-child{margin-top:30px}.css-z468a2{width:100%;max-width:550px;position:relative;margin:0 auto}.css-jy1umg{display:flex;line-height:20px;align-items:center;flex-direction:row;font-weight:400;margin-bottom:20px;font-size:14px}.css-1q67gt9{flex:none;height:50px;width:50px;line-height:0;margin-right:20px;position:relative}.css-quwpxp{border-radius:100%;overflow:hidden;background-color:#c0dcdf}.css-7u7i0a{margin-bottom:20px;margin-top:20px;font-weight:600}.css-20w1gi{clear:both;margin-left:auto;margin-right:auto;margin-top:30px;margin-bottom:30px;min-height:250px;width:300px;display:block}.css-1t05dkn{display:block;justify-content:center;min-height:250px;width:300px}.css-1sq15os{z-index:0;clear:both;position:relative;text-align:center;display:block;margin-left:-10px;margin-right:-10px;min-height:250px;width:300px}.css-1sq15os::before{content:'ADVERTISEMENT';display:block;position:absolute;top:-20px;left:0;right:0;height:20px;font-size:9px;line-height:20px;-webkit-letter-spacing:1px;-moz-letter-spacing:1px;letter-spacing:1px;color:#bcbfc5}.css-1sq15os:empty::before{display:none}.css-1ubyuqj{margin-bottom:30px;margin-bottom:0;line-height:26px}.css-1ubyuqj ul{padding-inline-start:20px;list-style-image:url("data:image/svg+xml,%3Csvg width='10' height='10' xmlns='http://www.w3.org/2000/svg'%3E%3Ccircle cx='5' cy='5' r='1.5' fill='%23000000'/%3E%3C/svg%3E")}.css-1vedeqe{margin-bottom:0;margin-top:20px;position:relative;opacity:0;top:-10px;transition:all 500ms cubic-bezier(0.165,0.84,0.44,1)}.css-1vedeqe cite{font-style:normal}.css-1vedeqe cite a{text-decoration:underline}.css-82r5pg{display:none;flex:none;margin-left:50px;width:300px}.css-npv6dx{border-bottom:8px solid #231f20}.css-lizeih{display:flex;line-height:20px;align-items:center;flex-direction:row;font-weight:400;margin-bottom:20px;font-size:14px;padding-top:13px;margin-top:25px}.css-488q2e{display:block;justify-content:center;height:600px;display:flex}.css-1d8h8gm{z-index:0;clear:both;position:relative;text-align:center;display:none;margin-left:-10px;margin-right:-10px;margin-bottom:200px}.css-1d8h8gm::before{content:'ADVERTISEMENT';display:block;top:-20px;left:0;right:0;height:20px;font-size:9px;line-height:20px;-webkit-letter-spacing:1px;-moz-letter-spacing:1px;letter-spacing:1px;color:#bcbfc5}.css-1d8h8gm:empty::before{display:none}.css-1g3kp27{font-size:15px;line-height:18px;-webkit-letter-spacing:1px;-moz-letter-spacing:1px;letter-spacing:1px;font-family:"Proxima Nova Condensed","Proxima Nova Condensed Fallback",sans-serif;font-weight:700;text-transform:uppercase;margin-top:0;margin-bottom:24px;font-family:"Proxima Nova Condensed","Proxima Nova Condensed Fallback",sans-serif;font-weight:700;font-size:20px;line-height:26px}.css-1r7frvz{width:100%;max-width:550px;position:relative;margin:0 auto;flex:1;max-width:100%}.css-1r7frvz::after{content:"";clear:both;display:block;height:8px;margin-top:40px;margin-left:-20px;margin-right:-20px;background:#f7f7f7}.css-rwmw5v{display:block;text-align:center;font-size:0;line-height:0;outline:none;position:relative;-webkit-touch-callout:none;-webkit-user-select:none;-moz-user-select:none;user-select:none;z-index:0}.css-1lyqwde{left:0;bottom:0;top:0}.css-1767n2d{display:block}.css-1fb1nmp{width:100%;height:100%;position:absolute;display:flex;justify-content:center;align-items:center;top:0;left:0;z-index:0}.css-sqa1yu{cursor:pointer;text-decoration:none;border-color:currentColor;color:#02838d;color:inherit;font-family:"Proxima Nova Condensed","Proxima Nova Condensed Fallback",sans-serif;font-weight:700;text-decoration:none;display:block;color:#231f20;margin:0;font-size:30px;line-height:34px}.css-sqa1yu:hover{color:#08565c}.css-sqa1yu:hover img,.css-sqa1yu:hover .image{opacity:0.8}.css-sqa1yu:hover svg{fill:currentColor}.css-sqa1yu:active{color:#9b1561}.css-8he51f{display:flex;line-height:20px;align-items:center;flex-direction:row;font-weight:400;margin-bottom:15px;font-size:14px;margin-top:15px;color:#767474}.css-1pz7193{flex:none;height:35px;width:35px;line-height:0;margin-right:20px;position:relative}.css-onvglr{cursor:pointer;text-decoration:none;color:inherit;margin:10px 0 20px 0;overflow:hidden;-webkit-box-orient:vertical;-webkit-line-clamp:calc(2);display:-webkit-box}.css-ysgmro{cursor:pointer;text-decoration:none;border-color:currentColor;color:#02838d;margin-top:30px;margin-bottom:0}.css-ysgmro:hover{color:#08565c}.css-ysgmro:hover img,.css-ysgmro:hover .image{opacity:0.8}.css-ysgmro:hover svg{fill:currentColor}.css-ysgmro:active{color:#9b1561}.css-prb4v6{display:block;justify-content:center}.css-vhteyv{z-index:0;clear:both;position:relative;text-align:center;display:none;margin-left:-10px;margin-right:-10px;margin-bottom:0}.css-vhteyv::before{content:'ADVERTISEMENT';display:block;position:absolute;top:-20px;left:0;right:0;height:20px;font-size:9px;line-height:20px;-webkit-letter-spacing:1px;-moz-letter-spacing:1px;letter-spacing:1px;color:#bcbfc5}.css-vhteyv:empty::before{display:none}.css-79elbk{position:relative}.css-i9gxme{flex-grow:1}.css-1dytfcg{font-size:14px;background-color:#fbf5ed}.css-1dppxl0{margin-left:0;margin-right:0;max-width:none;width:100%;padding:40px 0}.css-1b2ri56{display:flex;flex-direction:column;align-items:center}.css-uktbta{width:100%;max-width:550px}.css-1xceiwh{display:flex;flex-direction:column;align-items:center;justify-content:space-between}.css-10ohy14{display:flex;flex-direction:row;justify-content:space-around;flex-wrap:wrap;max-width:max-content}.css-lb03wr{display:flex;flex-direction:column;align-items:flex-start;list-style:none;padding:0;margin:0;font-family:inherit;color:inherit}.css-34bq4y{display:list-item;margin:0 0 20px;font-size:14px;line-height:20px;font-weight:600}.css-1qz7cpo{cursor:pointer;text-decoration:none;border-color:currentColor;color:#02838d;color:#231f20;font-weight:600;display:inline-block;padding:4px 0;text-decoration:none}.css-1qz7cpo:hover{color:#08565c}.css-1qz7cpo:hover img,.css-1qz7cpo:hover .image{opacity:0.8}.css-1qz7cpo:hover svg{fill:currentColor}.css-1qz7cpo:active{color:#9b1561}.css-1qz7cpo:hover{color:#08565c}.css-159kw12{-webkit-appearance:none;-moz-appearance:none;appearance:none;background:none;border:none;padding:4px 0;border-radius:0;color:#231f20;font-weight:600;display:inline-block;text-decoration:none}.css-159kw12:hover{color:#08565c}.css-16bllps{font-weight:normal;font-size:14px;width:100%;padding:0 20px;color:#231f20}.css-1xx5q6{color:#231f20}.css-1us2gxx{background-color:#000000;width:100%;color:#dcdbdb;font-family:"Proxima Nova","Proxima Nova Fallback",sans-serif}.css-11upubx{margin-left:0;margin-right:0;max-width:none;width:100%;display:flex;flex-direction:column;justify-content:flex-end;align-items:center;padding:40px 0 50px}.css-t5u34a{cursor:pointer;text-decoration:none;border-color:currentColor;color:#02838d;display:inline-block;margin-right:0}.css-t5u34a:hover{color:#08565c}.css-t5u34a:hover img,.css-t5u34a:hover .image{opacity:0.8}.css-t5u34a:hover svg{fill:currentColor}.css-t5u34a:active{color:#9b1561}.css-d2oo9m{display:flex;flex-direction:column;justify-content:flex-end}.css-s2uf1z{text-align:right}.css-s65yls{cursor:pointer;text-decoration:none;border-color:currentColor;color:#02838d;text-decoration:underline;color:#dcdbdb;display:inline-block}.css-s65yls:hover{color:#08565c}.css-s65yls:hover img,.css-s65yls:hover .image{opacity:0.8}.css-s65yls:hover svg{fill:currentColor}.css-s65yls:active{color:#9b1561}.css-s65yls:after{display:inline-block;content:'|';margin:0 1rem;cursor:default}.css-s65yls:last-of-type:{margin-right:0}.css-s65yls:last-of-type::after{display:none;margin-left:0}.css-s65yls:hover{color:#08565c}.css-s65yls:hover:after{color:#dcdbdb}.css-huujs8{display:flex;flex-direction:column;flex-wrap:nowrap;justify-content:flex-start;align-items:center;margin-top:30px;margin-bottom:40px;line-height:20px}.css-1vtxghn{display:inline-block;font-size:14px;margin:0;padding:0;font-weight:bold;color:#dcdbdb;font-family:"Proxima Nova","Proxima Nova Fallback",sans-serif}.css-d9t9tq{cursor:pointer;text-decoration:none;border-color:currentColor;color:#02838d;text-decoration:underline;color:#dcdbdb;margin-right:0}.css-d9t9tq:hover{color:#08565c}.css-d9t9tq:hover img,.css-d9t9tq:hover .image{opacity:0.8}.css-d9t9tq:hover svg{fill:currentColor}.css-d9t9tq:active{color:#9b1561}.css-d9t9tq:last-of-type{margin-right:0}.css-d9t9tq:hover{color:#08565c} @media(min-width:768px){h2.with-image-at-left{float:right}h2.with-image-at-right{float:left}h2.with-image-at-left,h2.with-image-at-right{width:calc(100% - 280px)}html{font-size:18px;line-height:1.44;}html,body{overflow-anchor:none;}h1,.h1{font-size:50px;line-height:54px;margin-bottom:30px;margin-top:30px;}h2,.h2{font-size:38px;line-height:42px;margin-top:45px;}h3,.h3{font-size:26px;line-height:30px;margin-bottom:20px;margin-top:35px;}h4{font-size:22px;margin-bottom:20px;margin-top:25px;}li{font-size:18px;}p,.p{margin-bottom:25px;margin-top:25px;font-size:18px;}.css-w2pt6r{font-size:28px;line-height:36px;margin:30px 0;}.css-17ztj4b{margin-left:-15px;}.css-t753mo:after{top:4px;height:22px;width:2px;}.css-t753mo{font-size:28px;line-height:40px;}.css-1r1p1p8{font-size:20px;line-height:40px;padding:0 15px;}.css-f0t0lw{margin-right:30px;width:200px}.css-m260rd{max-width:989px;width:calc(100vw - 110px);}.css-tqpz90{height:70px;}.css-1w3ble7{flex:0 0 120px;}.css-cs3emt{margin-right:20px;}.css-x4xfyn{height:18px;width:34px;}.css-18bsjiu{height:20px;}.css-1g6cesj{align-items:center;justify-content:center;flex:1 0 auto;}.css-12mc611{width:168px;height:27px;}.css-1bqkt1y{width:168px;height:27px;}.css-10adefi{justify-content:flex-start;}.css-1bdb0zy{padding-top:30px;border-top-width:2px;}.css-lembgb{margin-right:20px;margin-left:0px;}.css-1a25cod{display:none}.css-v5umvf{font-size:15px;}.css-1ur4f3m{display:none}.css-1wm8u43{display:flex;}.css-1jpwf16{min-height:90px;width:728px;}.css-1j2d96m{display:block;min-height:90px;width:728px;}.css-pdceuf{display:none;}.css-1fteite{display:none;}.css-z468a2{max-width:879px;}.css-jy1umg{font-weight:600;margin-bottom:25px;font-size:16px;}.css-7u7i0a{margin-bottom:30px;margin-top:30px;}.css-20w1gi{margin-top:40px;}.css-1sq15os{margin-left:auto;margin-right:auto;}.css-lizeih{font-weight:600;margin-bottom:25px;font-size:16px;}.css-1d8h8gm{margin-left:auto;margin-right:auto;}.css-1g3kp27{font-size:24px;}.css-1r7frvz::after{margin-left:0;margin-right:0;}.css-1r7frvz{max-width:879px;}.css-lm0pdr{display:flex}.css-sqa1yu{font-size:38px;line-height:44px;}.css-8he51f{font-weight:600;}.css-ysgmro{margin-top:20px;}.css-vhteyv{margin-left:auto;margin-right:auto;}.css-10ohy14{max-width:375px;}.css-16bllps{padding:0;}} @media(min-width:990px){.css-m260rd{max-width:1100px;width:calc(100vw - 90px);}.css-1w3ble7{display:none;}.css-cs3emt{display:none;}.css-10aca47{display:none;}.css-1g6cesj{justify-content:normal;flex:0 1 auto;}.css-1wyiq3l{display:block;}.css-dke6ht{padding-bottom:5px;margin-bottom:10px;}.css-16uojuo{max-height:50px;max-width:50px;}.css-1n6ef6i{height:50px;width:50px;min-width:50px;}.css-1wtf0mw{justify-content:flex-start;}.css-bbu8su{justify-content:flex-start;}.css-1bdb0zy a::before{font-size:30px;line-height:30px;}.css-1bdb0zy a{width:30px;height:30px;margin-right:50px;}.css-2dofw9{display:inline;align-items:normal;}.css-1h1rean{display:flex;}.css-blwnmv{display:flex;}.css-z468a2{width:calc(100% - 350px);max-width:750px;}.css-jy1umg{display:none}.css-1q67gt9{height:75px;width:75px;}.css-20w1gi{display:none;}.css-1sq15os{display:none;}.css-82r5pg{display:block;}.css-lizeih{font-weight:600}.css-488q2e{min-height:250px;width:300px;}.css-1d8h8gm{display:block;min-height:250px;width:300px;}.css-1r7frvz{width:calc(100% - 350px);max-width:750px;}.css-8he51f{font-weight:600}.css-prb4v6{min-height:250px;width:300px;}.css-vhteyv{display:block;min-height:250px;width:300px;}.css-1dppxl0{margin-left:auto;margin-right:auto;max-width:1100px;width:calc(100vw - 90px);padding:60px 0;}.css-1b2ri56{flex-direction:row;align-items:flex-start;}.css-uktbta{width:50%;}.css-1xceiwh{align-items:flex-start;}.css-10ohy14{max-width:max-content;}.css-11upubx{margin-left:auto;margin-right:auto;max-width:1100px;width:calc(100vw - 90px);flex-direction:row;padding:35px 0;}.css-t5u34a{margin-right:auto;}.css-huujs8{flex-direction:row;margin-top:15px;margin-bottom:0;}.css-1vtxghn{margin:0 20px 0 0;}.css-d9t9tq{margin-right:20px;}} @media(min-width:1190px){.css-20w1gi{min-height:90px;width:728px;display:block;}.css-1t05dkn{min-height:90px;width:728px;}.css-1sq15os{display:block;min-height:90px;width:728px;}} @media (max-width:320px){.css-1g6cesj{margin-right:5px}} @media(max-width:767px){.css-8q0s1n{margin-bottom:16px;border-bottom:2px solid #dcdbdb}}</style> </head><body><noscript><iframe title="GTM-noscript" src="https://gtm-server.healthline.com/ns.html?id=GTM-MB6365D" style="display:none;visibility:hidden;width:0;height:0"></iframe></noscript><svg style="display:none"><defs><svg id="logo-hl" xmlns="http://www.w3.org/2000/svg" width="2500" height="400" viewBox="0 0 2500 400"><path d="M328.766 388.827H209.127v-189.81c0-19.952-14.278-32.742-31.092-32.742-16.32 0-36.038 13.302-36.038 32.743v189.809H34.617V86.463L0 61.905C39.563 48.603 105.896 19.953 141.997 0v158.6c14.342-17.906 49.39-40.929 93.9-40.929 56.377 0 80.61 37.348 80.61 81.859v160.247c0 4.82 4.086 14.504 12.26 29.05zm1233.178 0h-119.639v-189.81c0-19.952-14.278-32.742-31.092-32.742-16.32 0-36.038 13.302-36.038 32.743v189.809h-107.38V86.463l-34.617-24.558C1272.741 48.603 1339.074 19.953 1375.175 0v158.6c14.342-17.906 49.39-40.929 93.9-40.929 56.377 0 80.61 37.348 80.61 81.859v160.247c0 4.82 4.086 14.504 12.26 29.05zm-971.656-45.14v18.942C566.479 383.106 540.19 400 483.646 400c-89.281 0-143.842-59.896-143.842-133.615 0-88.053 56.049-147.95 138.386-147.95 81.345 0 112.098 55.802 112.098 125.937H441.589c6.448 80.885 51.481 117.745 92.65 117.745 19.84 0 42.16-6.655 56.049-18.43zM473.108 228.46c23.931 0 26.662-6.819 26.662-26.837 0-15.348-2.73-53.18-26.661-53.18-23.93 0-26.661 37.832-26.661 53.18 0 20.018 2.73 26.837 26.66 26.837zM2500 343.609v18.942c-23.808 20.477-50.097 37.371-106.642 37.371-89.28 0-143.842-59.896-143.842-133.615 0-88.053 56.05-147.95 138.386-147.95 81.346 0 112.098 55.802 112.098 125.937h-148.698c6.448 80.886 51.48 117.745 92.65 117.745 19.84 0 42.16-6.655 56.048-18.43zm-117.179-115.228c23.93 0 26.661-6.819 26.661-26.837 0-15.348-2.73-53.18-26.66-53.18-23.931 0-26.662 37.832-26.662 53.18 0 20.018 2.73 26.837 26.661 26.837zM893.751 341.354l11.878 2.522C900.195 365.821 884.362 400 833.422 400c-42.533 0-54.467-26.109-63.369-53.753C762.635 371.844 733.52 400 678.128 400c-49.457 0-76.658-22.013-76.658-63.48 0-46.074 44.941-79.862 157.208-113.138V174.75c0-25.085-13.353-33.788-28.19-33.788-13.354 0-34.556 14.334-34.556 36.86 0 10.75 1.979 18.94 3.462 29.691 0 13.823-15.826 34.812-40.06 34.812-26.706 0-39.565-19.454-39.565-41.979 0-36.859 34.125-81.91 123.642-81.91 92.978 0 122.652 49.147 122.652 96.245v124.912c0 7.679 2.968 15.358 11.375 15.358 7.419 0 12.468-4.217 16.313-13.596zm-134.484-9.444v-92.757c-37.614 15.29-50.635 53.004-50.635 82.055 0 23.444 7.234 34.147 24.594 34.147 15.191 0 26.041-9.684 26.041-23.445zm288.256 56.917H924.01V86.463L891.1 61.905C928.711 48.603 997.822 19.953 1032.142 0v359.777c0 4.595 5.127 14.279 15.38 29.05zm676.806 0h-123.513V86.463l-32.91-24.558C1605.518 48.603 1674.628 19.953 1708.948 0v359.777c0 4.595 5.127 14.279 15.38 29.05zm-491.603-31.332v18.948C1214.728 391.806 1184.89 400 1152.684 400c-53.045 0-71.516-39.432-71.516-72.719V149.354h-25.582L1190.1 31.284v97.3h42.626v20.77H1190.1v192.778c0 15.363 8.999 22.533 19.892 22.533 6.63 0 18.471-3.073 22.734-7.17zm594.239-243.249c-30.57 0-54.931-25.332-54.931-57.123 0-31.79 24.36-57.123 54.93-57.123 30.571 0 54.932 25.333 54.932 57.123s-24.36 57.123-54.931 57.123zm72.303 274.58h-126.086V198.453l-34.695-24.63c39.652-13.342 106.147-42.078 142.329-62.09v248.045c0 4.776 6.15 14.46 18.452 29.05zm342.178 0h-123.517V198.453c0-20.012-14.278-32.84-31.092-32.84-16.32 0-36.038 13.341-36.038 32.84v190.373h-107.38V198.453l-34.617-24.63c39.563-13.342 103.072-42.078 139.174-62.09v52.34c17.803-23.604 52.213-47.209 96.722-47.209 56.378 0 80.61 37.46 80.61 82.102v160.812c0 4.688 5.38 14.372 16.138 29.05z"></path></svg><svg id="icon-hamburger" xmlns="http://www.w3.org/2000/svg" width="40" height="25" viewBox="0 0 40 25"><path d="M38 3H2L0 2V1l2-1h36l1 1v1l-1 1zm0 11H2l-2-1v-1l2-1h36l1 1v1l-1 1zm0 11H2l-2-1v-1l2-1h36l1 1v1l-1 1z"></path></svg><svg id="icon-hamburger-menu" xmlns="http://www.w3.org/2000/svg" width="30" height="19" viewBox="0 0 30 19"><path d="M29.823 17.211c.236.38.236.864 0 1.244-.233.38-.663.589-1.1.537H1.276a1.136 1.136 0 0 1-1.1-.537 1.186 1.186 0 0 1 0-1.244 1.14 1.14 0 0 1 1.1-.537h27.447c.437-.051.867.158 1.1.537zm0-8.333c.236.38.236.864 0 1.244-.233.38-.663.589-1.1.537H1.276a1.138 1.138 0 0 1-1.1-.537 1.186 1.186 0 0 1 0-1.244c.234-.38.663-.589 1.1-.537h27.447c.437-.052.867.158 1.1.537zm0-8.333c.236.38.236.863 0 1.244a1.139 1.139 0 0 1-1.1.537H1.276a1.14 1.14 0 0 1-1.1-.537 1.186 1.186 0 0 1 0-1.244c.234-.38.663-.589 1.1-.537h27.447c.437-.052.867.157 1.1.537z"></path></svg><svg id="icon-search" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink" width="40" height="40" viewBox="0 0 41 41"><defs><path id="a" d="M16.4 28a11.7 11.7 0 1 1 0-23.4 11.7 11.7 0 0 1 0 23.5zm22.9 8-9.8-10a16 16 0 0 0 3.2-9.6A16.3 16.3 0 0 0 1.7 9C-1.7 15.8.1 24 6 29a16.4 16.4 0 0 0 20.4.4l9.7 10a2.3 2.3 0 0 0 4-1 2.3 2.3 0 0 0-.8-2.2z"></path></defs><use xlink:href="#a" fill-rule="evenodd"></use></svg><svg id="icon-close" xmlns="http://www.w3.org/2000/svg" width="40" height="40" viewBox="0 0 40 40"><path d="M23.65 20 39 4.66A2.587 2.587 0 1 0 35.34 1L20 16.35 4.66 1A2.587 2.587 0 1 0 1 4.66L16.35 20 1 35.34A2.587 2.587 0 1 0 4.66 39L20 23.65 35.34 39A2.587 2.587 0 1 0 39 35.34z"></path></svg></defs></svg><div id="top-of-page"></div><div id="modal-host"></div><div class="__chrome"><div id="__next"><span class="css-zya54r"></span><div id="ZN_0VXyKJxsXo4lIpw" data-testid="qualtrics-container"></div><div class="css-fdjy12"><span style="font-size:0;line-height:0"></span><div class="css-12wdr8u"><div id="site-header" data-testid="header-ux3" class="css-1m3pkrv"><div class="css-m260rd"><div class="css-tqpz90"><div class="css-1w3ble7"><div class="css-cs3emt"><button type="button" class="css-x4xfyn" aria-pressed="false" aria-label="Main Menu" tabindex="0" data-testid="hamburger"><span style="transform:scale(1) translateY(0px)" class="css-qzkqso"></span><span style="transform:rotate(0deg)" class="css-wyg90z"></span><span style="transform:rotate(0deg)" class="css-wyg90z"></span><span style="transform:scale(1) translateY(0px)" class="css-m8s3k4"></span></button></div><div class="css-10aca47"><svg viewBox="0 0 41 41" width="40" height="40" class="css-18bsjiu"><use xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="#icon-search"></use></svg></div></div><div class="css-1g6cesj logo-wrapper"><div class="css-12mc611"><a class="css-1bqkt1y" data-event="|Global Header|Logo Click" data-element-event="INTERNAL LINK|HEADER|Any Page|GLOBAL HEADER|LOGO|Healthline|" href="https://www.healthline.com/" data-testid="site-logo"><svg class="css-yc5e1l logo" viewBox="0 0 2500 400"><title>Healthline</title><use xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="#logo-hl"></use></svg></a></div></div><div style="opacity:1" class="css-1wyiq3l"><ul role="menubar" class="css-1oanbjp" data-testid="desktop-nav-bar"><li class="css-114osio" role="none"><button class="css-198d8b5" role="menuitem" tabindex="0" aria-haspopup="true" aria-label="Expand Health Conditions options" aria-controls="nav-panel-flyout" type="button" aria-expanded="false"><span>Health Conditions</span><svg xmlns="http://www.w3.org/2000/svg" width="30" height="30" viewBox="0 0 30 30"><path d="M27.963 6.75 30 8.787l-1.018 1.018-12.964 12.963L15 23.787 1.018 9.805 0 8.787 2.037 6.75l1.018 1.018L15 19.713 26.945 7.768l1.018-1.018z"></path></svg></button><div style="display:none" aria-hidden="true"><div><h3>Featured</h3><a class="css-dke6ht" href="https://www.healthline.com/conditions"><span class="css-yer60s">All</span><span class="css-ajcamw icon-hl-circle-arrow"></span></a><ul><li><a class="css-1c2ok3c" href="https://www.healthline.com/breast-cancer">Breast Cancer</a></li><li><a class="css-1c2ok3c" href="https://www.healthline.com/inflammatory-bowel-disease">IBD </a></li><li><a class="css-1c2ok3c" href="https://www.healthline.com/migraine">Migraine</a></li><li><a class="css-1c2ok3c" href="https://www.healthline.com/multiple-sclerosis">Multiple Sclerosis (MS)</a></li><li><a class="css-1c2ok3c" href="https://www.healthline.com/rheumatoid-arthritis">Rheumatoid Arthritis</a></li><li><a class="css-1c2ok3c" href="https://www.healthline.com/type-2-diabetes">Type 2 Diabetes</a></li><li><a class="css-1c2ok3c" href="https://www.healthline.com/sponsored-topics">Sponsored Topics</a></li></ul></div><div><h3>Articles</h3><a class="css-dke6ht" href="https://www.healthline.com/directory/topics"><span class="css-yer60s">All</span><span class="css-ajcamw icon-hl-circle-arrow"></span></a><ul><li><a class="css-1c2ok3c" href="https://www.healthline.com/health/gerd">Acid Reflux</a></li><li><a class="css-1c2ok3c" href="https://www.healthline.com/health/adhd">ADHD</a></li><li><a class="css-1c2ok3c" href="https://www.healthline.com/health/allergies">Allergies</a></li><li><a class="css-1c2ok3c" href="https://www.healthline.com/health/alzheimers-disease">Alzheimer's & Dementia</a></li><li><a class="css-1c2ok3c" href="https://www.healthline.com/health/bipolar-disorder">Bipolar Disorder</a></li><li><a class="css-1c2ok3c" href="https://www.healthline.com/health/cancer">Cancer</a></li><li><a class="css-1c2ok3c" href="https://www.healthline.com/health/crohns-disease">Crohn's Disease</a></li><li><a class="css-1c2ok3c" href="https://www.healthline.com/health/chronic-pain">Chronic Pain</a></li><li><a class="css-1c2ok3c" href="https://www.healthline.com/health/cold-flu">Cold & Flu</a></li><li><a class="css-1c2ok3c" href="https://www.healthline.com/health/copd">COPD</a></li><li><a class="css-1c2ok3c" href="https://www.healthline.com/health/depression">Depression</a></li><li><a class="css-1c2ok3c" href="https://www.healthline.com/health/fibromyalgia">Fibromyalgia</a></li><li><a class="css-1c2ok3c" href="https://www.healthline.com/health/heart-disease">Heart Disease</a></li><li><a class="css-1c2ok3c" href="https://www.healthline.com/health/high-cholesterol">High Cholesterol</a></li><li><a class="css-1c2ok3c" href="https://www.healthline.com/health/hiv-aids">HIV</a></li><li><a class="css-1c2ok3c" href="https://www.healthline.com/health/high-blood-pressure-hypertension">Hypertension</a></li><li><a class="css-1c2ok3c" href="https://www.healthline.com/health/managing-idiopathic-pulmonary-fibrosis">IPF</a></li><li><a class="css-1c2ok3c" href="https://www.healthline.com/health/osteoarthritis">Osteoarthritis</a></li><li><a class="css-1c2ok3c" href="https://www.healthline.com/health/psoriasis">Psoriasis</a></li><li><a class="css-1c2ok3c" href="https://www.healthline.com/health/skin-disorders">Skin Disorders and Care</a></li><li><a class="css-1c2ok3c" href="https://www.healthline.com/health/sexually-transmitted-diseases">STDs</a></li></ul></div></div></li><li class="css-114osio" role="none"><button class="css-198d8b5" role="menuitem" tabindex="0" aria-haspopup="true" aria-label="Expand Discover options" aria-controls="nav-panel-flyout" type="button" aria-expanded="false"><span>Discover</span><svg xmlns="http://www.w3.org/2000/svg" width="30" height="30" viewBox="0 0 30 30"><path d="M27.963 6.75 30 8.787l-1.018 1.018-12.964 12.963L15 23.787 1.018 9.805 0 8.787 2.037 6.75l1.018 1.018L15 19.713 26.945 7.768l1.018-1.018z"></path></svg></button><div style="display:none" aria-hidden="true"><div><h3>Wellness Topics</h3><a class="css-dke6ht" href="https://www.healthline.com/wellness"><span class="css-yer60s">All</span><span class="css-ajcamw icon-hl-circle-arrow"></span></a><ul><li><a class="css-1c2ok3c" href="https://www.healthline.com/nutrition">Nutrition</a></li><li><a class="css-1c2ok3c" href="https://www.healthline.com/fitness">Fitness</a></li><li><a class="css-1c2ok3c" href="https://www.healthline.com/skincare">Skin Care</a></li><li><a class="css-1c2ok3c" href="https://www.healthline.com/sexual-health">Sexual Health</a></li><li><a class="css-1c2ok3c" href="https://www.healthline.com/program/wellness">Women's Health</a></li><li><a class="css-1c2ok3c" href="https://www.healthline.com/mental-health">Mental Well-Being</a></li><li><a class="css-1c2ok3c" href="https://www.healthline.com/sleep">Sleep</a></li></ul></div><div><h3>Product Reviews</h3><a class="css-dke6ht" href="https://www.healthline.com/reviews"><span class="css-yer60s">All</span><span class="css-ajcamw icon-hl-circle-arrow"></span></a><ul><li><a class="css-1c2ok3c" href="https://www.healthline.com/reviews/vitamin-and-supplement-products">Vitamins & Supplements</a></li><li><a class="css-1c2ok3c" href="https://www.healthline.com/reviews/sleep-products">Sleep</a></li><li><a class="css-1c2ok3c" href="https://www.healthline.com/reviews/mental-health-services-and-products">Mental Health</a></li><li><a class="css-1c2ok3c" href="https://www.healthline.com/reviews/nutrition-products">Nutrition</a></li><li><a class="css-1c2ok3c" href="https://www.healthline.com/reviews/at-home-testing-products">At-Home Testing</a></li><li><a class="css-1c2ok3c" href="https://www.healthline.com/reviews/cbd-products">CBD</a></li><li><a class="css-1c2ok3c" href="https://www.healthline.com/reviews/mens-health-products">Men’s Health</a></li></ul></div><div><h3>Original Series</h3><a class="css-dke6ht" href="https://www.healthline.com/series"><span class="css-yer60s">All</span><span class="css-ajcamw icon-hl-circle-arrow"></span></a><ul><li><a class="css-1c2ok3c" href="https://www.healthline.com/content-series/fresh-food-fast"><div class="css-10adefi"><div class="css-1n6ef6i"><img src="https://media.post.rvohealth.io/wp-content/uploads/2021/07/FFF_lead-logo4-23.png?w=240&h=240" alt="" class="css-16uojuo"/></div><div><span class="css-1wtf0mw">Fresh Food Fast</span><div class="css-8sow18">Food hacks to make eating healthier, easier.</div></div></div></a></li><li><a class="css-1c2ok3c" href="https://www.healthline.com/content-series/diagnosis-diaries"><div class="css-10adefi"><div class="css-1n6ef6i"><img src="https://media.post.rvohealth.io/wp-content/uploads/2022/07/HL-icon-diagnosis-diaries-1.png" alt="" class="css-16uojuo"/></div><div><span class="css-1wtf0mw">Diagnosis Diaries</span><div class="css-8sow18">Real diagnosis stories from people who get it.</div></div></div></a></li><li><a class="css-1c2ok3c" href="https://www.healthline.com/content-series/youre-not-alone"><div class="css-10adefi"><div class="css-1n6ef6i"><img src="https://media.post.rvohealth.io/wp-content/uploads/2022/07/HL-icon-youre-not-alone-1.png" alt="" class="css-16uojuo"/></div><div><span class="css-1wtf0mw">You’re Not Alone</span><div class="css-8sow18">Stories from real people that destigmatize mental health conditions.</div></div></div></a></li><li><a class="css-1c2ok3c" href="https://www.healthline.com/content-series/present-tense"><div class="css-10adefi"><div class="css-1n6ef6i"><img src="https://media.post.rvohealth.io/wp-content/uploads/2021/05/HL-Content_Series-Present_Tense-Series_Logo-500x500-Series_Logo.png" alt="" class="css-16uojuo"/></div><div><span class="css-1wtf0mw">Present Tense</span><div class="css-8sow18">Real-world mindfulness for busy people.</div></div></div></a></li></ul></div><div><h3>Video Series</h3><a class="css-dke6ht" href="https://www.healthline.com/video"><span class="css-yer60s">All</span><span class="css-ajcamw icon-hl-circle-arrow"></span></a><ul><li><a class="css-1c2ok3c" href="https://www.healthline.com/health/video/youth-in-focus"><div class="css-10adefi"><div class="css-1n6ef6i"><img src="https://media.post.rvohealth.io/wp-content/uploads/2022/07/240x240-Youth-in-Focus.png" alt="" class="css-16uojuo"/></div><div><span class="css-1wtf0mw">Youth in Focus</span><div class="css-8sow18">Mental health challenges facing our youth.</div></div></div></a></li><li><a class="css-1c2ok3c" href="https://www.healthline.com/health/nutrition/video/healthy-harvest"><div class="css-10adefi"><div class="css-1n6ef6i"><img src="https://media.post.rvohealth.io/wp-content/uploads/2022/09/Healthy_harvest_icon_Artboard-4-transformed.png" alt="" class="css-16uojuo"/></div><div><span class="css-1wtf0mw">Healthy Harvest</span><div class="css-8sow18">Meet your food, from farm to table.</div></div></div></a></li><li><a class="css-1c2ok3c" href="https://www.healthline.com/health/breast-cancer/metastatic-breast-cancer-artist-eye"><div class="css-10adefi"><div class="css-1n6ef6i"><img src="https://media.post.rvohealth.io/wp-content/uploads/2023/10/Through_an_artists_eye-07.png" alt="" class="css-16uojuo"/></div><div><span class="css-1wtf0mw">Through An Artist's Eye</span><div class="css-8sow18">A breast cancer story told through art.</div></div></div></a></li><li><a class="css-1c2ok3c" href="https://www.healthline.com/health/video/future-of-health"><div class="css-10adefi"><div class="css-1n6ef6i"><img src="https://media.post.rvohealth.io/wp-content/uploads/2022/07/HL-icon-future-of-health-1.png" alt="" class="css-16uojuo"/></div><div><span class="css-1wtf0mw">Future of Health</span><div class="css-8sow18">Innovations shaping the future of health.</div></div></div></a></li></ul></div></div></li><li class="css-114osio" role="none"><button class="css-198d8b5" role="menuitem" tabindex="0" aria-haspopup="true" aria-label="Expand Plan options" aria-controls="nav-panel-flyout" type="button" aria-expanded="false"><span>Plan</span><svg xmlns="http://www.w3.org/2000/svg" width="30" height="30" viewBox="0 0 30 30"><path d="M27.963 6.75 30 8.787l-1.018 1.018-12.964 12.963L15 23.787 1.018 9.805 0 8.787 2.037 6.75l1.018 1.018L15 19.713 26.945 7.768l1.018-1.018z"></path></svg></button><div style="display:none" aria-hidden="true"><div><h3>Health Challenges</h3><ul><li><a class="css-1c2ok3c" href="https://www.healthline.com/newsletter-signup/mindfulness-challenge">Mindful Eating</a></li><li><a class="css-1c2ok3c" href="https://www.healthline.com/newsletter-signup/sugar-challenge">Sugar Savvy</a></li><li><a class="css-1c2ok3c" href="https://www.healthline.com/newsletter-signup/move-your-body-challenge">Move Your Body</a></li><li><a class="css-1c2ok3c" href="https://www.healthline.com/newsletter-signup/gut-check-challenge">Gut Health</a></li><li><a class="css-1c2ok3c" href="https://www.healthline.com/newsletter-signup/mood-foods-challenge">Mood Foods</a></li><li><a class="css-1c2ok3c" href="https://www.healthline.com/newsletter-signup/align-your-spine-challenge">Align Your Spine</a></li></ul></div><div><h3>Find Care</h3><a class="css-dke6ht" target="_blank" rel="noopener noreferrer" href="https://care.healthline.com/find-care/specialty"><span class="css-yer60s">All</span><span class="css-ajcamw icon-hl-circle-arrow"></span></a><ul><li><a class="css-1c2ok3c" target="_blank" rel="noopener noreferrer" href="https://care.healthline.com/find-care/specialty/primary-care-doctors?ref=global">Primary Care</a></li><li><a class="css-1c2ok3c" target="_blank" rel="noopener noreferrer" href="https://care.healthline.com/find-care/specialty/mental-health-professional?ref=global">Mental Health</a></li><li><a class="css-1c2ok3c" target="_blank" rel="noopener noreferrer" href="https://care.healthline.com/find-care/specialty/obstetrics-gynecology?ref=global">OB-GYN</a></li><li><a class="css-1c2ok3c" target="_blank" rel="noopener noreferrer" href="https://care.healthline.com/find-care/specialty/dermatology?ref=global">Dermatologists</a></li><li><a class="css-1c2ok3c" target="_blank" rel="noopener noreferrer" href="https://care.healthline.com/find-care/specialty/neurology?ref=global">Neurologists</a></li><li><a class="css-1c2ok3c" target="_blank" rel="noopener noreferrer" href="https://care.healthline.com/find-care/specialty/cardiology?ref=global">Cardiologists</a></li><li><a class="css-1c2ok3c" target="_blank" rel="noopener noreferrer" href="https://care.healthline.com/find-care/specialty/orthopedic-surgery?ref=global">Orthopedists</a></li></ul></div><div><h3>Lifestyle Quizzes</h3><ul><li><a class="css-1c2ok3c" href="https://www.healthline.com/nutrition/weight-management-quiz">Weight Management</a></li><li><a class="css-1c2ok3c" href="https://www.healthline.com/health/depression/teenage-quiz">Am I Depressed? A Quiz for Teens</a></li><li><a class="css-1c2ok3c" href="https://www.healthline.com/health/mental-health/quiz-are-you-a-workaholic#quiz-are-you-a-workaholic">Are You a Workaholic?</a></li><li><a class="css-1c2ok3c" href="https://www.healthline.com/health/healthy-sleep/quiz-how-well-do-you-sleep">How Well Do You Sleep?</a></li></ul></div><div><h3>Tools & Resources</h3><ul><li><a class="css-1c2ok3c" target="_blank" href="https://www.healthline.com/health-news">Health News</a></li><li><a class="css-1c2ok3c" target="_blank" rel="noopener noreferrer nofollow" href="https://activation.healthline.com/assessment/assessment/diets/prompt/1?v=1&tc=120226&subid=hl_dietfinder_1_">Find a Diet</a></li><li><a class="css-1c2ok3c" target="_blank" rel="noopener noreferrer nofollow" href="https://activation.healthline.com/assessment/assessment/pregnancy-snacks/prompt/1?v=1">Find Healthy Snacks</a></li><li><a class="css-1c2ok3c" href="https://www.healthline.com/drugs">Drugs A-Z</a></li><li><a class="css-1c2ok3c" href="https://www.healthline.com/directory/topics">Health A-Z</a></li></ul></div></div></li><li class="css-114osio" role="none"><button class="css-198d8b5" role="menuitem" tabindex="0" aria-haspopup="true" aria-label="Expand Connect options" aria-controls="nav-panel-flyout" type="button" aria-expanded="false"><span>Connect</span><svg xmlns="http://www.w3.org/2000/svg" width="30" height="30" viewBox="0 0 30 30"><path d="M27.963 6.75 30 8.787l-1.018 1.018-12.964 12.963L15 23.787 1.018 9.805 0 8.787 2.037 6.75l1.018 1.018L15 19.713 26.945 7.768l1.018-1.018z"></path></svg></button><div style="display:none" aria-hidden="true"><div><h3>Find Your Bezzy Community</h3><p>Bezzy communities provide meaningful connections with others living with chronic conditions. Join Bezzy on the web or mobile app.</p><a class="css-dke6ht" target="_blank" rel="noopener noreferrer" href="https://www.bezzy.com/?utm_source=healthline&utm_medium=nav-bar-connections"><span class="css-yer60s">All</span><span class="css-ajcamw icon-hl-circle-arrow"></span></a><ul><li><a class="css-1c2ok3c" target="_blank" rel="noopener noreferrer" href="https://www.bezzybc.com/lp/2/?verzenio&utm_source=healthline&utm_medium=nav-bar-connections" aria-label="Visit the Breat Cancer community"><div class="css-10adefi"><div class="css-1dm1ger"><img src="https://media.post.rvohealth.io/wp-content/uploads/2022/01/Bezzy-Breast-Cancer.png" alt="" class="css-1q1spi4"/></div><div><span class="css-bbu8su">Breast Cancer</span></div></div></a></li><li><a class="css-1c2ok3c" target="_blank" rel="noopener noreferrer" href="https://www.bezzyibd.com/?utm_source=healthline&utm_medium=nav-bar-connections" aria-label="Visit the Inflammatory Bowel Disease community"><div class="css-10adefi"><div class="css-1dm1ger"><img src="https://media.post.rvohealth.io/wp-content/uploads/2022/01/Bezzy-Inflammatory-Bowel-Disease.png" alt="" class="css-1q1spi4"/></div><div><span class="css-bbu8su">Inflammatory Bowel Disease</span></div></div></a></li><li><a class="css-1c2ok3c" target="_blank" rel="noopener noreferrer" href="https://www.bezzydepression.com/?auvelity&utm_source=healthline&utm_medium=nav-bar-connections" aria-label="Visit the Depression community"><div class="css-10adefi"><div class="css-1dm1ger"><img src="https://media.post.rvohealth.io/wp-content/uploads/2024/11/Bezzy-DEP-Icon-Circle.png" alt="" class="css-1q1spi4"/></div><div><span class="css-bbu8su">Depression</span></div></div></a></li><li><a class="css-1c2ok3c" target="_blank" rel="noopener noreferrer" href="https://www.bezzymigraine.com/?utm_source=healthline&utm_medium=nav-bar-connections" aria-label="Visit the Migraine community"><div class="css-10adefi"><div class="css-1dm1ger"><img src="https://media.post.rvohealth.io/wp-content/uploads/2022/01/Bezzy-Migraine.png" alt="" class="css-1q1spi4"/></div><div><span class="css-bbu8su">Migraine</span></div></div></a></li><li><a class="css-1c2ok3c" target="_blank" rel="noopener noreferrer" href="https://www.bezzyms.com/?utm_source=healthline&utm_medium=nav-bar-connections" aria-label="Visit the Multiple Sclerosis community"><div class="css-10adefi"><div class="css-1dm1ger"><img src="https://media.post.rvohealth.io/wp-content/uploads/2022/01/Bezzy-Multiple-Sclerosis.png" alt="" class="css-1q1spi4"/></div><div><span class="css-bbu8su">Multiple Sclerosis</span></div></div></a></li><li><a class="css-1c2ok3c" target="_blank" rel="noopener noreferrer" href="https://www.bezzypsoriasis.com/?utm_source=healthline&utm_medium=nav-bar-connections" aria-label="Visit the Psoriasis community"><div class="css-10adefi"><div class="css-1dm1ger"><img src="https://media.post.rvohealth.io/wp-content/uploads/2022/04/Bezzy-PsO.png" alt="" class="css-1q1spi4"/></div><div><span class="css-bbu8su">Psoriasis</span></div></div></a></li></ul></div><div><h3>Follow us on social media</h3><p>Can't get enough? Connect with us for all things health.</p><div role="menu" class="css-1bdb0zy"><a class="icon-hl-facebook css-lembgb" target="_blank" rel="noopener noreferrer" data-event="|social channel footer click|Facebook channel icon clicked" href="http://www.facebook.com/pages/Healthline/173263326992" aria-label="Visit our Facebook page"></a><a class="icon-hl-twitter css-lembgb" target="_blank" rel="noopener noreferrer" data-event="|social channel footer click|Twitter channel icon clicked" href="https://twitter.com/healthline" aria-label="Visit our Twitter page"></a><a class="icon-hl-instagram css-lembgb" target="_blank" rel="noopener noreferrer" data-event="|social channel footer click|Instagram channel icon clicked" href="http://www.instagram.com/healthline" aria-label="Visit our Instagram page"></a><a class="icon-hl-linkedin css-lembgb" target="_blank" rel="noopener noreferrer" data-event="|social channel footer click|LinkedIn channel icon clicked" href="https://www.linkedin.com/company/healthline-media/" aria-label="Visit our LinkedIn page"></a><a class="icon-hl-youtube-new css-lembgb" target="_blank" rel="noopener noreferrer" data-event="|social channel footer click|YoutTube channel icon clicked" href="https://www.youtube.com/channel/UC7snF15Idi7px6XujWe_h9A" aria-label="Visit our YouTube page"></a><a class="icon-hl-flipboard css-lembgb" target="_blank" rel="noopener noreferrer" data-event="|social channel footer click|Flipboard channel icon clicked" href="https://flipboard.com/@healthline" aria-label="Visit our Flipboard page"></a></div></div></div></li></ul></div><div class="css-12qvns3"><div class="css-1a25cod"></div><button aria-label="Click to Subscribe to our Newsletter" id="newsletter-subscription-button" data-test-id="newsletter-subscribe-button" aria-haspopup="dialog" class="css-v5umvf"><span class="css-19k7c2f">Subscribe</span></button><div class="css-1ur4f3m"></div></div><div class="css-2dofw9"></div></div></div></div><div class="css-ifmqwy"></div></div><div class="css-16wahxh"><aside class="css-1wm8u43" data-testid="header-leaderboard" data-sticky="true"><div data-empty="true" class="css-1j2d96m"><div class="css-1hjaa0k"><span class="css-zya54r"></span></div><div id="dlb1__slot" data-adbridg-ad-class="dlb1" data-ad="true" class="css-1jpwf16"></div></div></aside></div><aside data-testid="mobile-leaderboard" class="css-pdceuf"><div class="css-11egx89"><button class="icon-hl-close-thick css-16m9poz"></button><div data-empty="true" class="css-1fteite"><div class="css-1hjaa0k"><span class="css-zya54r"></span></div><div id="mlb1__slot" data-adbridg-ad-class="mlb1" data-ad="true" class="css-bcus5s"></div></div></div></aside><div data-placement="subheader"></div><div><div class="css-m260rd"><div data-article-body="0" class="css-blwnmv"><div class="css-z468a2"><h1>A Simple Guide to the Endocannabinoid System</h1><div data-preamp="social-proof-lessons"></div><div data-testid="byline"><section data-testid="byline" class="css-jy1umg"><div class="css-1q67gt9"><div class="css-quwpxp"><img src="//i0.wp.com/post.healthline.com/wp-content/uploads/2022/01/Alan-Carter-500x500-Bio.png?w=105&h=105" alt=""/></div></div><div><span><span><a class="css-1c2ok3c css-ro87dg" target="_blank" rel="noopener noreferrer">Medically reviewed</a> by <a class="css-1c2ok3c css-ro87dg" target="_blank" rel="noopener noreferrer">Alan Carter, Pharm.D.</a></span></span> — <span><span><span><span>Written by <a class="css-1c2ok3c css-ro87dg" target="_blank" rel="noopener noreferrer">Crystal Raypole</a></span></span></span></span> <span> on May 17, 2019</span></div></section></div><div><nav id="tab-bar-0" data-testid="tab-bar" class="css-7u7i0a"><ul class="css-17ztj4b"><li class="css-t753mo"><a href="#how-it-works" class="css-1r1p1p8">How it works</a></li><li class="css-t753mo"><a href="#functions" class="css-1r1p1p8">Functions</a></li><li class="css-t753mo"><a href="#thc" class="css-1r1p1p8">THC</a></li><li class="css-t753mo"><a href="#cbd" class="css-1r1p1p8">CBD</a></li><li class="css-t753mo"><a href="#deficiency" class="css-1r1p1p8">Deficiency</a></li><li class="css-t753mo"><a href="#takeaway" class="css-1r1p1p8">Takeaway</a></li></ul></nav><article class="article-body css-d2znx6 undefined"><div class="css-12va8w7"><span style="font-size:0;line-height:0"></span><span style="font-size:0;line-height:0"></span><div><div><p class="css-w2pt6r">The endocannabinoid system (ECS) is a complex cell-signaling system that helps regulate your body functions, including sleep and mood, among others.</p></div></div><div><p>It was identified in the early 1990s by researchers exploring THC, a well-known cannabinoid. Cannabinoids are compounds found in <a href="https://www.healthline.com/health/what-is-cannabis" class="content-link css-1c2ok3c">cannabis</a>.</p></div><div><div data-preamp="serena-chatbot"></div></div><div><p>Experts are still trying to fully understand the ECS. But so far, we know it plays role in regulating a range of functions and processes, including:</p></div><div><ul><li>sleep</li><li>mood</li><li>appetite</li><li>memory</li><li>reproduction and fertility</li></ul></div><div><p>The ECS exists and is active in your body even if you don’t use cannabis. </p></div><div><p>Read on to learn more about the ECS including how it works and interacts with cannabis.</p></div><div class="css-20w1gi"><aside class="css-0 css-0" data-testid="sticky-inline-ad" data-sticky="false"><div><div data-empty="true" class="css-1sq15os"><div class="css-1hjaa0k"><span class="css-zya54r"></span></div><div id="inline2__slot" data-adbridg-ad-class="inline2__slot" data-ad="true" class="css-1t05dkn"></div></div></div></aside></div></div><div class="css-1avyp1d"><span style="font-size:0;line-height:0"></span><div><h2><div><a class="chartbeat-section" name="how-it-works">How does it work?</a></div></h2></div><span style="font-size:0;line-height:0"></span><div><p>The ECS involves three core components: endocannabinoids, receptors, and enzymes.</p></div><div><h3><strong>Endocannabinoids</strong></h3></div><div><p>Endocannabinoids, also called endogenous cannabinoids, are molecules made by your body. They’re similar to cannabinoids, but they’re produced by your body.</p></div><div><p>Experts have identified two key endocannabinoids so far:</p></div><div><ul><li> anandamide (AEA)</li><li> 2-arachidonoylglyerol (2-AG)</li></ul></div><div><p>These help keep internal functions running smoothly. Your body produces them as needed, making it difficult to know what typical levels are for each. </p></div><div><h3>Endocannabinoid receptors</h3></div><div><p>These receptors are found throughout your body. Endocannabinoids bind to them in order to signal that the ECS needs to take action.</p></div><div><p>There are two main endocannabinoid receptors:</p></div><div><ul><li>CB1 receptors, which are mostly found in the central nervous system</li><li>CB2 receptors, which are mostly found in your peripheral nervous system, especially immune cells</li></ul></div><div><p>Endocannabinoids can bind to either receptor. The effects that result depend on where the receptor is located and which endocannabinoid it binds to. </p></div><div><p>For example, endocannabinoids might target CB1 receptors in a spinal nerve to relieve pain. Others might bind to a CB2 receptor in your immune cells to signal that your body’s experiencing inflammation, a common sign of autoimmune disorders. </p></div><div><h3>Enzymes</h3></div><div><p>Enzymes are responsible for breaking down endocannabinoids once they’ve carried out their function.</p></div><div><p>There are two main enzymes responsible for this:</p></div><div><ul><li>fatty acid amide hydrolase, which breaks down AEA</li><li>monoacylglycerol acid lipase, which typically breaks down 2-AG</li></ul></div><span class="css-zya54r"></span></div><div class="css-1avyp1d"><span style="font-size:0;line-height:0"></span><div><h2><div><a class="chartbeat-section" name="functions">What are its functions?</a></div></h2></div><span style="font-size:0;line-height:0"></span><div><p>The ECS is complicated, and experts haven’t yet determined exactly how it works or all of its potential functions. </p></div><div><p><hl-trusted-source source="PubMed Central" rationale="Highly respected database from the National Institutes of Health"><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877694/" target="_blank" rel="noopener noreferrer" class="content-link css-1c2ok3c">Research</a></hl-trusted-source> has linked the ECS to the following processes: </p></div><div><ul><li>appetite and digestion</li><li>metabolism </li><li><a href="https://www.healthline.com/health/chronic-pain" class="content-link css-1c2ok3c">chronic pain</a></li><li><a href="https://www.healthline.com/health/chronic-inflammation" class="content-link css-1c2ok3c">inflammation</a> and other immune system responses</li><li>mood </li><li>learning and memory </li><li>motor control</li><li>sleep</li><li>cardiovascular system function </li><li>muscle formation </li><li>bone remodeling and growth</li><li>liver function</li><li>reproductive system function</li><li><a href="https://www.healthline.com/health/stress" class="content-link css-1c2ok3c">stress</a></li><li>skin and nerve function </li></ul></div><div><p>These functions all contribute to homeostasis, which refers to stability of your internal environment. For example, if an outside force, such as pain from an injury or a fever, throws off your body’s homeostasis, your ECS kicks in to help your body return to its ideal operation. </p></div><div><p>Today, experts believe that maintaining homeostasis if the primary role of the ECS.</p></div></div><div class="css-1avyp1d"><span style="font-size:0;line-height:0"></span><div><h2><div><a class="chartbeat-section" name="thc">How does THC interact with the ECS?</a></div></h2></div><span style="font-size:0;line-height:0"></span><div><p>Tetrahydrocannabinol (THC) is one of the main cannabinoids found in cannabis. It’s the compound that gets you “high.” </p></div><div><p>Once in your body, THC interacts with your ECS by binding to receptors, just like endocannabinoids. It’s powerful partly because it can bind to both CB1 and CB2 receptors. </p></div><div><p>This allows it to have a range of effects on your body and mind, some more desirable than others. For example, THC may help to reduce pain and stimulate your appetite. But it can also cause paranoia and anxiety in some cases. </p></div><div><p>Experts are currently looking into ways to produce synthetic THC cannabinoids that interact with the ECS in only beneficial ways. </p></div><span class="css-zya54r"></span></div><div class="css-1avyp1d"><span style="font-size:0;line-height:0"></span><div><h2><div><a class="chartbeat-section" name="cbd">How does CBD interact with the ECS?</a></div></h2></div><span style="font-size:0;line-height:0"></span><div><p>The other major cannabinoid found in cannabis is cannabidiol (CBD). Unlike THC, CBD doesn’t make you “high” and typically doesn’t cause any negative effects. </p></div><div><p>Experts aren’t completely sure how CBD interacts with the ECS. But they do know that it doesn’t bind to CB1 or CB2 receptors the way THC does. </p></div><div><p>Instead, many believe it works by preventing endocannabinoids from being broken down. This allows them to have more of an effect on your body. Others believe that CBD binds to a receptor that hasn’t been discovered yet. </p></div><div><p>While the details of how it works are still under debate, research suggests that CBD can help with pain, nausea, and other symptoms associated with multiple conditions. </p></div></div><div class="css-1avyp1d"><span style="font-size:0;line-height:0"></span><div><h2><div><a class="chartbeat-section" name="deficiency">What about endocannabinoid deficiency?</a></div></h2></div><span style="font-size:0;line-height:0"></span><div><p>Some experts believe in a theory known as clinical endocannabinoid deficiency (CECD). This theory suggests that low endocannabinoid levels in your body or ECS dysfunction can contribute to the development of certain conditions.</p></div><div><p>A <hl-trusted-source source="PubMed Central" rationale="Highly respected database from the National Institutes of Health"><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576607/" target="_blank" rel="noopener noreferrer" class="content-link css-1c2ok3c">2016 article</a></hl-trusted-source> reviewing over 10 years of research on the subject suggests the theory could explain why some people develop <a href="https://www.healthline.com/health/migraine" class="content-link css-1c2ok3c">migraine</a>, <a href="https://www.healthline.com/health/fibromyalgia" class="content-link css-1c2ok3c">fibromyalgia</a>, and <a href="https://www.healthline.com/health/irritable-bowel-syndrome" class="content-link css-1c2ok3c">irritable bowel syndrome</a>. </p></div><div><p>None of these conditions have a clear underlying cause. They’re also often resistant to treatment and sometimes occur alongside each other. </p></div><div><p>If CECD does play any kind of role in these conditions, targeting the ECS or endocannabinoid production could be the missing key to treatment, but more research is needed.</p></div><div class="css-20w1gi"><aside class="css-0 css-0" data-testid="sticky-inline-ad" data-sticky="false"><div><div data-empty="true" class="css-1sq15os"><div class="css-1hjaa0k"><span class="css-zya54r"></span></div><div id="inline13__slot" data-adbridg-ad-class="inline13__slot" data-ad="true" class="css-1t05dkn"></div></div></div></aside></div></div><div class="css-1avyp1d"><span style="font-size:0;line-height:0"></span><div><h2><div><a class="chartbeat-section" name="takeaway">The bottom line</a></div></h2></div><span style="font-size:0;line-height:0"></span><div><p>The ECS plays a big role in keeping your internal processes stable. But there’s still a lot we don’t know about it. As experts develop a better understanding of the ECS, it could eventually hold the key to treating several conditions. </p></div></div></article><span class="css-zya54r"></span></div><div><div class="css-8q0s1n css-10dx3t"><div class="css-15lc7zf"><h3 id="bylineArticleTools">How we reviewed this article:</h3><div class="css-vrhe66"><button type="button" class="css-5sudr5"><div class="css-rre5oz"><span class="css-1d75hb8"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" fill="none" viewBox="0 0 20 20"><path fill="currentColor" fill-rule="evenodd" d="M0 10C0 4.477 4.477 0 10 0s10 4.477 10 10-4.477 10-10 10S0 15.523 0 10Zm18.5 0a8.5 8.5 0 1 0-17 0 8.5 8.5 0 0 0 17 0ZM10 4c-.823 0-1.5.677-1.5 1.518C8.5 6.323 9.177 7 10 7c.841 0 1.5-.677 1.5-1.482A1.5 1.5 0 0 0 10 4Zm0 4.5a1 1 0 0 1 1 1V15a1 1 0 1 1-2 0V9.5a1 1 0 0 1 1-1Z" clip-rule="evenodd"></path></svg></span><span>Sources</span></div></button><button type="button" open="" class="css-5sudr5"><div class="css-rre5oz"><span class="css-1d75hb8"><svg xmlns="http://www.w3.org/2000/svg" width="22" height="20" fill="none" viewBox="0 0 22 20"><path fill="currentColor" d="M3.181 9.732c.43 0 .793-.003 1.157 0 .66.007 1.023.613.696 1.19a221.037 221.037 0 0 1-1.774 3.072c-.329.557-1.038.553-1.366-.007-.6-1.02-1.191-2.043-1.774-3.072-.325-.575.043-1.177.708-1.183h.808c.055-.447.088-.882.165-1.309.557-3.104 2.187-5.489 4.913-7.056 3.679-2.114 8.05-1.75 11.352.913 2.062 1.664 3.29 3.84 3.625 6.473.678 5.323-3.012 10.254-8.308 11.103-3.215.515-6.044-.356-8.476-2.515-.297-.259-.373-.598-.233-.92.14-.323.454-.52.805-.454.187.04.361.13.504.26a8.618 8.618 0 0 0 4.383 2.108c3.72.63 7.513-1.394 9.084-4.846a8.521 8.521 0 0 0-6.047-11.911C8.763.618 4.201 3.71 3.353 8.4c-.078.427-.112.863-.172 1.331Z"></path><path fill="currentColor" d="M10.12 7.212V3.711a.778.778 0 0 1 1.535-.171c.017.104.024.21.02.314v6.25a.412.412 0 0 0 .168.368c1.125.89 2.241 1.791 3.362 2.686.26.208.405.466.342.803-.11.583-.76.829-1.244.459-.485-.37-.952-.756-1.427-1.135-.79-.633-1.578-1.27-2.373-1.898a.933.933 0 0 1-.385-.793c.008-1.125.003-2.252.003-3.382Z"></path></svg></span><span>History</span></div></button></div><div class="css-1ndif92"><div class="css-1ubyuqj"><div id="article-resources" role="region" class="css-1ugaz02"><div class="css-0">Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical journals and associations. We only use quality, credible sources to ensure content accuracy and integrity. You can learn more about how we ensure our content is accurate and current by reading our <a class="css-1c2ok3c" href="https://www.healthline.com/about/process">editorial policy</a>.</div><ul class="css-1vedeqe"><li class="css-1ti7iub"><cite><span>Ahn K, et al. (2008). Enzymatic pathways that regulate endocannabinoid signaling in the nervous system. DOI:</span><br/><a class="css-1c2ok3c css-1ivue52" target="_blank" rel="noopener noreferrer" href="https://doi.org/10.1021%2Fcr0782067">https://doi.org/10.1021%2Fcr0782067</a></cite></li><li class="css-1ti7iub"><cite><span>Alger BE. (2013). Getting high on the endocannabinoid system.</span><br/><a class="css-1c2ok3c css-1ivue52" target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997295">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997295</a></cite></li><li class="css-1ti7iub"><cite><span>Background: Marijuana. (2007).</span><br/><a class="css-1c2ok3c css-1ivue52" target="_blank" rel="noopener noreferrer" href="https://www.drugabuse.gov/publications/brain-power/grades-6-9/weeding-out-grass-module-4/background">https://www.drugabuse.gov/publications/brain-power/grades-6-9/weeding-out-grass-module-4/background</a></cite></li><li class="css-1ti7iub"><cite><span>Cannabidiol (CBD) Pre-review report. (2017).</span><br/><a class="css-1c2ok3c css-1ivue52" target="_blank" rel="noopener noreferrer" href="https://www.who.int/medicines/access/controlled-substances/5.2_CBD.pdf">https://www.who.int/medicines/access/controlled-substances/5.2_CBD.pdf</a></cite></li><li class="css-1ti7iub"><cite><span>Cannabis and cannabinoids. (2019).</span><br/><a class="css-1c2ok3c css-1ivue52" target="_blank" rel="noopener noreferrer" href="https://www.cancer.gov/about-cancer/treatment/cam/patient/cannabis-pdq?redirect=true">https://www.cancer.gov/about-cancer/treatment/cam/patient/cannabis-pdq?redirect=true</a></cite></li><li class="css-1ti7iub"><cite><span>Clinical endocannabinoid deficiency: Issue brief on clinical endocannabinoid deficiency. (2017). </span><br/><a class="css-1c2ok3c css-1ivue52" target="_blank" rel="noopener noreferrer" href="https://www.health.state.mn.us/people/cannabis/docs/rulemaking/endocannabinoidbrief.pdf">https://www.health.state.mn.us/people/cannabis/docs/rulemaking/endocannabinoidbrief.pdf</a></cite></li><li class="css-1ti7iub"><cite><span>De Laurentiis A, et al. (2014). Role of the endocannabinoid system in the neuroendocrine responses to inflammation. DOI:</span><br/><a class="css-1c2ok3c css-1ivue52" target="_blank" rel="noopener noreferrer" href="https://doi.org/10.2174/1381612820666140130212957">https://doi.org/10.2174/1381612820666140130212957</a></cite></li><li class="css-1ti7iub"><cite><span>de Morais H, et al. (2016). Anandamide reverses depressive-like behavior, neurochemical abnormalities and oxidative-stress parameters in streptozotocin-diabetic rats: Role of CB1 receptors. DOI:</span><br/><a class="css-1c2ok3c css-1ivue52" target="_blank" rel="noopener noreferrer" href="http://doi.org/10.1016/j.euroneuro.2016.08.007">http://doi.org/10.1016/j.euroneuro.2016.08.007</a></cite></li><li class="css-1ti7iub"><cite><span>Gomez M, et al. (2008). Cannabinoid signaling system.</span><br/><a class="css-1c2ok3c css-1ivue52" target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2633685">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2633685</a></cite></li><li class="css-1ti7iub"><cite><span>Gorzkiewicz A, et al. (2018). Brain endocannabinoid signaling exhibits remarkable complexity. DOI:</span><br/><a class="css-1c2ok3c css-1ivue52" target="_blank" rel="noopener noreferrer" href="https://doi.org/10.1016/j.brainresbull.2018.06.012">https://doi.org/10.1016/j.brainresbull.2018.06.012</a></cite></li><li class="css-1ti7iub"><cite><span>Human endocannabinoid system. (n.d.).</span><br/><a class="css-1c2ok3c css-1ivue52" target="_blank" rel="noopener noreferrer" href="https://www.uclahealth.org/cannabis/human-endocannabinoid-system">https://www.uclahealth.org/cannabis/human-endocannabinoid-system</a></cite></li><li class="css-1ti7iub"><cite><span>Lu H-C. (2015). An introduction to the endogenous cannabinoid system. DOI:</span><br/><a class="css-1c2ok3c css-1ivue52" target="_blank" rel="noopener noreferrer" href="https://doi.org/10.1016%2Fj.biopsych.2015.07.028">https://doi.org/10.1016%2Fj.biopsych.2015.07.028</a></cite></li><li class="css-1ti7iub"><cite><span>Maccarrone M, et al. (2015). Endocannabinoid signaling at the periphery: 50 years after THC. DOI:</span><br/><a class="css-1c2ok3c css-1ivue52" target="_blank" rel="noopener noreferrer" href="https://doi.org/10.1016%2Fj.tips.2015.02.008">https://doi.org/10.1016%2Fj.tips.2015.02.008</a></cite></li><li class="css-1ti7iub"><cite><span>Pacher P, et al. (2008). The endocannabinoid system as an emerging target of pharmacotherapy. DOI:</span><br/><a class="css-1c2ok3c css-1ivue52" target="_blank" rel="noopener noreferrer" href="https://doi.org/10.1124%2Fpr.58.3.2">https://doi.org/10.1124%2Fpr.58.3.2</a></cite></li><li class="css-1ti7iub"><cite><span>Russo EB. (2016). Clinical endocannabinoid deficiency reconsidered: Current research supports the theory in migraine, fibromyalgia, irritable bowel, and other treatment-resistant syndromes. DOI:</span><br/><a class="css-1c2ok3c css-1ivue52" target="_blank" rel="noopener noreferrer" href="https://doi.org/10.1089%2Fcan.2016.0009">https://doi.org/10.1089%2Fcan.2016.0009</a></cite></li><li class="css-1ti7iub"><cite><span>Sharma P, et al. (2012). Chemistry, metabolism, and toxicology of cannabis: Clinical implications.</span><br/><a class="css-1c2ok3c css-1ivue52" target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570572">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570572</a></cite></li><li class="css-1ti7iub"><cite><span>Smith SC, et al. (2014). Clinical endocannabinoid deficiency (CECD) revisited: Can this concept explain the therapeutic benefits of cannabis in migraine, fibromyalgia, irritable bowel syndrome and other treatment-resistant conditions?</span><br/><a class="css-1c2ok3c css-1ivue52" target="_blank" rel="noopener noreferrer" href="https://www.ncbi.nlm.nih.gov/pubmed/24977967">https://www.ncbi.nlm.nih.gov/pubmed/24977967</a></cite></li><li class="css-1ti7iub"><cite><span>Zou S, et al. (2018). Cannabinoid receptors and the endocannabinoid system: Signaling and function in the central nervous system. DOI:</span><br/><a class="css-1c2ok3c css-1ivue52" target="_blank" rel="noopener noreferrer" href="https://doi.org/10.3390%2Fijms19030833">https://doi.org/10.3390%2Fijms19030833</a></cite></li></ul></div></div></div><div open="" class="css-1ndif92"></div></div><div class="css-k1nhka" data-testid="share-tools"><p>Share this article</p><div class="css-14uyzrw"><div class="button-wrapper print"><a class="css-j5n0jw print button icon icon-hl-print" target="_blank" title="Print this page"></a></div><div class="button-wrapper email"><a class="css-j5n0jw email button icon icon-hl-email" target="_blank" title="Email this page"></a></div><div class="button-wrapper facebook"><a class="css-j5n0jw facebook button icon icon-hl-facebook" href="https://www.facebook.com/sharer/sharer.php?u=https%3A%2F%2Fwww.healthline.com%2Fhealth%2Fendocannabinoid-system%3Futm_medium%3Dsocial%26utm_source%3Dfacebook%26utm_campaign%3Dsocial-sharebar-referred-desktop" rel="noopener noreferrer nofollow" target="_blank" title="Share on Facebook"></a></div><div class="button-wrapper twitter"><a class="css-j5n0jw twitter button icon icon-hl-twitter" href="https://twitter.com/intent/tweet?via=healthline&text=Endocannabinoid%20System%3A%20A%20Simple%20Guide%20to%20How%20It%20Works&url=https%3A%2F%2Fwww.healthline.com%2Fhealth%2Fendocannabinoid-system%3Futm_medium%3Dsocial%26utm_source%3Dtwitter%26utm_campaign%3Dsocial-sharebar-referred-desktop" rel="noopener noreferrer nofollow" target="_blank" title="Share on Twitter"></a></div><div class="button-wrapper more"><a class="css-j5n0jw more button icon icon-hl-more" target="_blank" title="Show more"></a></div></div></div></div></div><span class="css-zya54r"></span></div><section style="position:relative;margin-top:0" class="css-82r5pg"><div class="css-dorrmn"><div class="css-npv6dx"><div data-testid="byline"><section data-testid="byline" class="css-lizeih"><div class="css-1q67gt9"><div class="css-quwpxp"><img src="//i0.wp.com/post.healthline.com/wp-content/uploads/2022/01/Alan-Carter-500x500-Bio.png?w=105&h=105" alt=""/></div></div><div><span><span><a class="css-1c2ok3c css-ro87dg" target="_blank" rel="noopener noreferrer">Medically reviewed</a> by <a class="css-1c2ok3c css-ro87dg" target="_blank" rel="noopener noreferrer">Alan Carter, Pharm.D.</a></span></span> — <span><span><span><span>Written by <a class="css-1c2ok3c css-ro87dg" target="_blank" rel="noopener noreferrer">Crystal Raypole</a></span></span></span></span> <span> on May 17, 2019</span></div></section></div></div></div><span class="css-zya54r"></span><div data-empty="true" class="css-1d8h8gm"><div class="css-1hjaa0k"><span class="css-zya54r"></span></div><div id="DMR1__slot" data-adbridg-ad-class="DMR1" data-ad="true" class="css-488q2e"></div></div><div class="css-h9jo37" data-dynamic-ads="true"><object type="text/html" data="about:blank" aria-label="advertisement" class="css-7vynax"></object></div></section></div></div></div><aside></aside><span style="font-size:0;line-height:0"></span><div><div id="read-next" class=" css-10ib5jr"><div class="css-m260rd"><div class="css-1h1rean"><div class="css-z468a2"><h3 class="css-1g3kp27">Read this next</h3></div><section class="css-82r5pg"></section></div></div><ul class="css-1l95nvm"><li class="css-12weawj"><div class="css-m260rd"><div class="css-1h1rean"><div class="css-1r7frvz"><div class="css-lm0pdr"><span style="font-size:0;line-height:0"></span><figure class="css-1e4ja14 css-f0t0lw"><a class="css-j5n0jw" data-event="engagement|bottom page content promo click|/health/fitness-exercise/definitive-guide-to-yoga;engagement|bottom page content promo click index|1" data-element-event="INTERNAL LINK|FOOTER|Any Page|Read This Next|LINK|The Definitive Guide to Yoga|rn0" href="https://www.healthline.com/health/fitness-exercise/definitive-guide-to-yoga?utm_source=ReadNext" aria-label="image-link" data-ga4="Read Next button clicks" data-testid="image-link" aria-hidden="true" tabindex="-1"><div class="css-79elbk"><span class="css-rwmw5v css-1pf0x3y"><span class="css-1767n2d"><lazy-image alt="The Definitive Guide to Yoga" src="https://media.post.rvohealth.io/wp-content/uploads/2020/08/Yoga_Tablet_Home_Female-732x549-Thumbnail-732x549.jpg" srcSet="https://media.post.rvohealth.io/wp-content/uploads/2020/08/Yoga_Tablet_Home_Female-732x549-Thumbnail-732x549.jpg 200w" className="css-1lyqwde"></lazy-image></span></span><span class="css-1fb1nmp"><span class="css-a10gts"></span></span></div></a></figure><div class="css-u8uhak"><a class="css-sqa1yu" data-event="engagement|bottom page content promo click|/health/fitness-exercise/definitive-guide-to-yoga;engagement|bottom page content promo click index|1" data-element-event="INTERNAL LINK|FOOTER|Any Page|Read This Next|LINK|The Definitive Guide to Yoga|rn0" href="https://www.healthline.com/health/fitness-exercise/definitive-guide-to-yoga?utm_source=ReadNext" data-testid="title-link" data-ga4="Read Next button clicks">The Definitive Guide to Yoga</a><section data-testid="byline" class="css-8he51f"><div class="css-1pz7193"><div class="css-quwpxp"><lazy-image alt="" src="https://media.post.rvohealth.io/wp-content/uploads/2022/01/Daniel-Bubnis-500x500-Bio.png"></lazy-image></div></div><div><span><span>Medically reviewed by <a class="css-1c2ok3c css-ro87dg" href="https://www.healthline.com/medical-team">Daniel Bubnis, M.S., NASM-CPT, NASE Level II-CSS</a></span></span></div></section><p class=""><a class="css-onvglr" data-event="engagement|bottom page content promo click|/health/fitness-exercise/definitive-guide-to-yoga;engagement|bottom page content promo click index|1" data-element-event="INTERNAL LINK|FOOTER|Any Page|Read This Next|LINK|The Definitive Guide to Yoga|rn0" href="https://www.healthline.com/health/fitness-exercise/definitive-guide-to-yoga?utm_source=ReadNext" data-testid="text-link" data-ga4="Read Next button clicks" aria-hidden="true" tabindex="-1">Whether you're a beginner or advanced yogi, here's our thorough guide to achieving a successful practice. Get expert advice, meditation tips, and more.</a></p><a class="css-v5yzal css-ysgmro" data-event="engagement|bottom page content promo click|/health/fitness-exercise/definitive-guide-to-yoga;engagement|bottom page content promo click index|1" data-element-event="INTERNAL LINK|FOOTER|Any Page|Read This Next|LINK|The Definitive Guide to Yoga|rn0" href="https://www.healthline.com/health/fitness-exercise/definitive-guide-to-yoga?utm_source=ReadNext" data-ga4="Read Next button clicks">READ MORE<span class="icon-hl-arrow-right selector css-2kgwd5"></span></a></div></div></div><section class="css-82r5pg css-1ub4i5m"><div data-empty="true" class="css-vhteyv"><div class="css-1hjaa0k"><span class="css-zya54r"></span></div><div id="DCMR1__slot" data-adbridg-ad-class="DCMR1" data-ad="true" class="css-prb4v6"></div></div></section></div></div></li><li class="css-12weawj"><div class="css-m260rd"><div class="css-1h1rean"><div class="css-1r7frvz"><span class="css-zya54r"></span></div><section class="css-82r5pg css-1ub4i5m"><div data-empty="true" class="css-vhteyv"><div class="css-1hjaa0k"><span class="css-zya54r"></span></div><div id="DCMR1__slot" data-adbridg-ad-class="DCMR1" data-ad="true" class="css-prb4v6"></div></div></section></div></div></li><li class="css-12weawj"><div class="css-m260rd"><div class="css-1h1rean"><div class="css-1r7frvz"><div class="css-lm0pdr"><span style="font-size:0;line-height:0"></span><figure class="css-1e4ja14 css-f0t0lw"><a class="css-j5n0jw" data-event="engagement|bottom page content promo click|/health/marijuana-paranoia;engagement|bottom page content promo click index|2" data-element-event="INTERNAL LINK|FOOTER|Any Page|Read This Next|LINK|Cannabis Got You Paranoid? How to Deal With It|rn1" href="https://www.healthline.com/health/marijuana-paranoia?utm_source=ReadNext" aria-label="image-link" data-ga4="Read Next button clicks" data-testid="image-link" aria-hidden="true" tabindex="-1"><div class="css-79elbk"><span class="css-rwmw5v css-1pf0x3y"><span class="css-1767n2d"><lazy-image alt="Cannabis Got You Paranoid? How to Deal With It" src="https://media.post.rvohealth.io/wp-content/uploads/2020/01/woman-home-eyes-closed-headphones-relaxing-732x549-thumbnail-732x549.jpg" srcSet="https://media.post.rvohealth.io/wp-content/uploads/2020/01/woman-home-eyes-closed-headphones-relaxing-732x549-thumbnail-732x549.jpg 200w" className="css-1lyqwde"></lazy-image></span></span><span class="css-1fb1nmp"><span class="css-a10gts"></span></span></div></a></figure><div class="css-u8uhak"><a class="css-sqa1yu" data-event="engagement|bottom page content promo click|/health/marijuana-paranoia;engagement|bottom page content promo click index|2" data-element-event="INTERNAL LINK|FOOTER|Any Page|Read This Next|LINK|Cannabis Got You Paranoid? How to Deal With It|rn1" href="https://www.healthline.com/health/marijuana-paranoia?utm_source=ReadNext" data-testid="title-link" data-ga4="Read Next button clicks">Cannabis Got You Paranoid? How to Deal With It</a><section data-testid="byline" class="css-8he51f"><div class="css-1pz7193"><div class="css-quwpxp"><lazy-image alt="" src="https://media.post.rvohealth.io/wp-content/uploads/2022/01/Debra-Sullivan-500x500-Bio.png"></lazy-image></div></div><div><span><span>Medically reviewed by <a class="css-1c2ok3c css-ro87dg" href="https://www.healthline.com/medical-team">Debra Sullivan, Ph.D., MSN, R.N., CNE, COI</a></span></span></div></section><p class=""><a class="css-onvglr" data-event="engagement|bottom page content promo click|/health/marijuana-paranoia;engagement|bottom page content promo click index|2" data-element-event="INTERNAL LINK|FOOTER|Any Page|Read This Next|LINK|Cannabis Got You Paranoid? How to Deal With It|rn1" href="https://www.healthline.com/health/marijuana-paranoia?utm_source=ReadNext" data-testid="text-link" data-ga4="Read Next button clicks" aria-hidden="true" tabindex="-1">Paranoia is one of the less desirable effects that marijuana has on some people. Learn why it happens, who's more likely to experience it, and how to…</a></p><a class="css-v5yzal css-ysgmro" data-event="engagement|bottom page content promo click|/health/marijuana-paranoia;engagement|bottom page content promo click index|2" data-element-event="INTERNAL LINK|FOOTER|Any Page|Read This Next|LINK|Cannabis Got You Paranoid? How to Deal With It|rn1" href="https://www.healthline.com/health/marijuana-paranoia?utm_source=ReadNext" data-ga4="Read Next button clicks">READ MORE<span class="icon-hl-arrow-right selector css-2kgwd5"></span></a></div></div></div><section class="css-82r5pg css-1ub4i5m"></section></div></div></li><li class="css-12weawj"><div class="css-m260rd"><div class="css-1h1rean"><div class="css-1r7frvz"><div class="css-lm0pdr"><span style="font-size:0;line-height:0"></span><figure class="css-1e4ja14 css-f0t0lw"><a class="css-j5n0jw" data-event="engagement|bottom page content promo click|/health/what-is-cannabis;engagement|bottom page content promo click index|3" data-element-event="INTERNAL LINK|FOOTER|Any Page|Read This Next|LINK|A Quick Take on Cannabis and Its Effects|rn2" href="https://www.healthline.com/health/what-is-cannabis?utm_source=ReadNext" aria-label="image-link" data-ga4="Read Next button clicks" data-testid="image-link" aria-hidden="true" tabindex="-1"><div class="css-79elbk"><span class="css-rwmw5v css-1pf0x3y"><span class="css-1767n2d"><lazy-image alt="A Quick Take on Cannabis and Its Effects" src="https://media.post.rvohealth.io/wp-content/uploads/2020/07/10269-What_Is_Cannabis-_Facts_About_Its_Components_Effects_and_Hazards_732x549-thumbnail-732x549.jpg" srcSet="https://media.post.rvohealth.io/wp-content/uploads/2020/07/10269-What_Is_Cannabis-_Facts_About_Its_Components_Effects_and_Hazards_732x549-thumbnail-732x549.jpg 200w" className="css-1lyqwde"></lazy-image></span></span><span class="css-1fb1nmp"><span class="css-a10gts"></span></span></div></a></figure><div class="css-u8uhak"><a class="css-sqa1yu" data-event="engagement|bottom page content promo click|/health/what-is-cannabis;engagement|bottom page content promo click index|3" data-element-event="INTERNAL LINK|FOOTER|Any Page|Read This Next|LINK|A Quick Take on Cannabis and Its Effects|rn2" href="https://www.healthline.com/health/what-is-cannabis?utm_source=ReadNext" data-testid="title-link" data-ga4="Read Next button clicks">A Quick Take on Cannabis and Its Effects</a><section data-testid="byline" class="css-8he51f"><div class="css-1pz7193"><div class="css-quwpxp"><lazy-image alt="" src="https://media.post.rvohealth.io/wp-content/uploads/2022/01/Femi-Aremu-500x500-Bio.png"></lazy-image></div></div><div><span><span>Medically reviewed by <a class="css-1c2ok3c css-ro87dg" href="https://www.healthline.com/medical-team">Femi Aremu, PharmD</a></span></span></div></section><p class=""><a class="css-onvglr" data-event="engagement|bottom page content promo click|/health/what-is-cannabis;engagement|bottom page content promo click index|3" data-element-event="INTERNAL LINK|FOOTER|Any Page|Read This Next|LINK|A Quick Take on Cannabis and Its Effects|rn2" href="https://www.healthline.com/health/what-is-cannabis?utm_source=ReadNext" data-testid="text-link" data-ga4="Read Next button clicks" aria-hidden="true" tabindex="-1">As weed becomes legal in more areas, names for it are evolving. Today, more and more people are using the term cannabis to refer to weed. Read on to…</a></p><a class="css-v5yzal css-ysgmro" data-event="engagement|bottom page content promo click|/health/what-is-cannabis;engagement|bottom page content promo click index|3" data-element-event="INTERNAL LINK|FOOTER|Any Page|Read This Next|LINK|A Quick Take on Cannabis and Its Effects|rn2" href="https://www.healthline.com/health/what-is-cannabis?utm_source=ReadNext" data-ga4="Read Next button clicks">READ MORE<span class="icon-hl-arrow-right selector css-2kgwd5"></span></a></div></div></div><section class="css-82r5pg css-1ub4i5m"><div data-empty="true" class="css-vhteyv"><div class="css-1hjaa0k"><span class="css-zya54r"></span></div><div id="DCMR2__slot" data-adbridg-ad-class="DCMR2" data-ad="true" class="css-prb4v6"></div></div></section></div></div></li><li class="css-12weawj"><div class="css-m260rd"><div class="css-1h1rean"><div class="css-1r7frvz"><div class="css-lm0pdr"><span style="font-size:0;line-height:0"></span><figure class="css-1e4ja14 css-f0t0lw"><a class="css-j5n0jw" data-event="engagement|bottom page content promo click|/health/video/marijuana-withdrawal;engagement|bottom page content promo click index|4" data-element-event="INTERNAL LINK|FOOTER|Any Page|Read This Next|LINK|Cannabis Withdrawal: What it is and What to Expect|rn3" href="https://www.healthline.com/health/video/marijuana-withdrawal?utm_source=ReadNext" aria-label="image-link" data-ga4="Read Next button clicks" data-testid="image-link" aria-hidden="true" tabindex="-1"><div class="css-79elbk"><span class="css-rwmw5v css-1pf0x3y"><span class="css-1767n2d"><lazy-image alt="Cannabis Withdrawal: What it is and What to Expect" src="https://media.post.rvohealth.io/wp-content/uploads/2020/09/2574-Young_man_smoking_Marijuana-732x549-thumbnail-732x549.jpg" srcSet="https://media.post.rvohealth.io/wp-content/uploads/2020/09/2574-Young_man_smoking_Marijuana-732x549-thumbnail-732x549.jpg 200w" className="css-1lyqwde"></lazy-image></span></span><span class="css-1fb1nmp"><span class="css-a10gts"></span></span></div></a></figure><div class="css-u8uhak"><a class="css-sqa1yu" data-event="engagement|bottom page content promo click|/health/video/marijuana-withdrawal;engagement|bottom page content promo click index|4" data-element-event="INTERNAL LINK|FOOTER|Any Page|Read This Next|LINK|Cannabis Withdrawal: What it is and What to Expect|rn3" href="https://www.healthline.com/health/video/marijuana-withdrawal?utm_source=ReadNext" data-testid="title-link" data-ga4="Read Next button clicks">Cannabis Withdrawal: What it is and What to Expect</a><section data-testid="byline" class="css-8he51f"><div><span><span>Medically reviewed by <a class="css-1c2ok3c css-ro87dg" href="https://www.healthline.com/medical-team">the Healthline Medical Network</a></span></span></div></section><p class=""><a class="css-onvglr" data-event="engagement|bottom page content promo click|/health/video/marijuana-withdrawal;engagement|bottom page content promo click index|4" data-element-event="INTERNAL LINK|FOOTER|Any Page|Read This Next|LINK|Cannabis Withdrawal: What it is and What to Expect|rn3" href="https://www.healthline.com/health/video/marijuana-withdrawal?utm_source=ReadNext" data-testid="text-link" data-ga4="Read Next button clicks" aria-hidden="true" tabindex="-1">It is possible to have cannabis use disorder, and when you stop using it, you can have withdrawal. Learn more. </a></p><a class="css-v5yzal css-ysgmro" data-event="engagement|bottom page content promo click|/health/video/marijuana-withdrawal;engagement|bottom page content promo click index|4" data-element-event="INTERNAL LINK|FOOTER|Any Page|Read This Next|LINK|Cannabis Withdrawal: What it is and What to Expect|rn3" href="https://www.healthline.com/health/video/marijuana-withdrawal?utm_source=ReadNext" data-ga4="Read Next button clicks">READ MORE<span class="icon-hl-arrow-right selector css-2kgwd5"></span></a></div></div></div><section class="css-82r5pg css-1ub4i5m"></section></div></div></li><li class="css-12weawj"><div class="css-m260rd"><div class="css-1h1rean"><div class="css-1r7frvz"><div class="css-lm0pdr"><span style="font-size:0;line-height:0"></span><figure class="css-1e4ja14 css-f0t0lw"><a class="css-j5n0jw" data-event="engagement|bottom page content promo click|/health-news/more-kids-getting-sick-from-edibles-as-legal-cannabis-expands;engagement|bottom page content promo click index|5" data-element-event="INTERNAL LINK|FOOTER|Any Page|Read This Next|LINK|As Legal Cannabis Expands, More Kids Are Getting Sick From Edibles|rn4" href="https://www.healthline.com/health-news/more-kids-getting-sick-from-edibles-as-legal-cannabis-expands?utm_source=ReadNext" aria-label="image-link" data-ga4="Read Next button clicks" data-testid="image-link" aria-hidden="true" tabindex="-1"><div class="css-79elbk"><span class="css-rwmw5v css-1pf0x3y"><span class="css-1767n2d"><lazy-image alt="As Legal Cannabis Expands, More Kids Are Getting Sick From Edibles" src="https://media.post.rvohealth.io/wp-content/uploads/2023/01/child-hand-brownie-732x549-thumbnail-732x549.jpg" srcSet="https://media.post.rvohealth.io/wp-content/uploads/2023/01/child-hand-brownie-732x549-thumbnail-732x549.jpg 200w" className="css-1lyqwde"></lazy-image></span></span><span class="css-1fb1nmp"><span class="css-a10gts"></span></span></div></a></figure><div class="css-u8uhak"><a class="css-sqa1yu" data-event="engagement|bottom page content promo click|/health-news/more-kids-getting-sick-from-edibles-as-legal-cannabis-expands;engagement|bottom page content promo click index|5" data-element-event="INTERNAL LINK|FOOTER|Any Page|Read This Next|LINK|As Legal Cannabis Expands, More Kids Are Getting Sick From Edibles|rn4" href="https://www.healthline.com/health-news/more-kids-getting-sick-from-edibles-as-legal-cannabis-expands?utm_source=ReadNext" data-testid="title-link" data-ga4="Read Next button clicks">As Legal Cannabis Expands, More Kids Are Getting Sick From Edibles</a><p class=""><a class="css-onvglr" data-event="engagement|bottom page content promo click|/health-news/more-kids-getting-sick-from-edibles-as-legal-cannabis-expands;engagement|bottom page content promo click index|5" data-element-event="INTERNAL LINK|FOOTER|Any Page|Read This Next|LINK|As Legal Cannabis Expands, More Kids Are Getting Sick From Edibles|rn4" href="https://www.healthline.com/health-news/more-kids-getting-sick-from-edibles-as-legal-cannabis-expands?utm_source=ReadNext" data-testid="text-link" data-ga4="Read Next button clicks" aria-hidden="true" tabindex="-1">U.S. poison control centers recorded more than 7,000 cases of children 6 and under who consumed cannabis edibles from 2017 to 2021, according to a new…</a></p><a class="css-v5yzal css-ysgmro" data-event="engagement|bottom page content promo click|/health-news/more-kids-getting-sick-from-edibles-as-legal-cannabis-expands;engagement|bottom page content promo click index|5" data-element-event="INTERNAL LINK|FOOTER|Any Page|Read This Next|LINK|As Legal Cannabis Expands, More Kids Are Getting Sick From Edibles|rn4" href="https://www.healthline.com/health-news/more-kids-getting-sick-from-edibles-as-legal-cannabis-expands?utm_source=ReadNext" data-ga4="Read Next button clicks">READ MORE<span class="icon-hl-arrow-right selector css-2kgwd5"></span></a></div></div></div><section class="css-82r5pg css-1ub4i5m"></section></div></div></li><li class="css-12weawj"><div class="css-m260rd"><div class="css-1h1rean"><div class="css-1r7frvz"><div class="css-lm0pdr"><span style="font-size:0;line-height:0"></span><figure class="css-1e4ja14 css-f0t0lw"><a class="css-j5n0jw" data-event="engagement|bottom page content promo click|/health/antibiotics/antibiotics-and-weed;engagement|bottom page content promo click index|6" data-element-event="INTERNAL LINK|FOOTER|Any Page|Read This Next|LINK|Can You Use Weed While You’re Taking Antibiotics?|rn5" href="https://www.healthline.com/health/antibiotics/antibiotics-and-weed?utm_source=ReadNext" aria-label="image-link" data-ga4="Read Next button clicks" data-testid="image-link" aria-hidden="true" tabindex="-1"><div class="css-79elbk"><span class="css-rwmw5v css-1pf0x3y"><span class="css-1767n2d"><lazy-image alt="Can You Use Weed While You’re Taking Antibiotics?" src="https://media.post.rvohealth.io/wp-content/uploads/2022/10/senior_rolling_marijuana_joint-732x549-thumbnail-732x549.jpg" srcSet="https://media.post.rvohealth.io/wp-content/uploads/2022/10/senior_rolling_marijuana_joint-732x549-thumbnail-732x549.jpg 200w" className="css-1lyqwde"></lazy-image></span></span><span class="css-1fb1nmp"><span class="css-a10gts"></span></span></div></a></figure><div class="css-u8uhak"><a class="css-sqa1yu" data-event="engagement|bottom page content promo click|/health/antibiotics/antibiotics-and-weed;engagement|bottom page content promo click index|6" data-element-event="INTERNAL LINK|FOOTER|Any Page|Read This Next|LINK|Can You Use Weed While You’re Taking Antibiotics?|rn5" href="https://www.healthline.com/health/antibiotics/antibiotics-and-weed?utm_source=ReadNext" data-testid="title-link" data-ga4="Read Next button clicks">Can You Use Weed While You’re Taking Antibiotics?</a><section data-testid="byline" class="css-8he51f"><div class="css-1pz7193"><div class="css-quwpxp"><lazy-image alt="" src="https://media.post.rvohealth.io/wp-content/uploads/2022/01/Alan-Carter-500x500-Bio.png"></lazy-image></div></div><div><span><span>Medically reviewed by <a class="css-1c2ok3c css-ro87dg" href="https://www.healthline.com/medical-team">Alan Carter, Pharm.D.</a></span></span></div></section><p class=""><a class="css-onvglr" data-event="engagement|bottom page content promo click|/health/antibiotics/antibiotics-and-weed;engagement|bottom page content promo click index|6" data-element-event="INTERNAL LINK|FOOTER|Any Page|Read This Next|LINK|Can You Use Weed While You’re Taking Antibiotics?|rn5" href="https://www.healthline.com/health/antibiotics/antibiotics-and-weed?utm_source=ReadNext" data-testid="text-link" data-ga4="Read Next button clicks" aria-hidden="true" tabindex="-1">The current research isn't certain whether it could have harmful or beneficial effects. Let's look at what you need to know if you plan on using…</a></p><a class="css-v5yzal css-ysgmro" data-event="engagement|bottom page content promo click|/health/antibiotics/antibiotics-and-weed;engagement|bottom page content promo click index|6" data-element-event="INTERNAL LINK|FOOTER|Any Page|Read This Next|LINK|Can You Use Weed While You’re Taking Antibiotics?|rn5" href="https://www.healthline.com/health/antibiotics/antibiotics-and-weed?utm_source=ReadNext" data-ga4="Read Next button clicks">READ MORE<span class="icon-hl-arrow-right selector css-2kgwd5"></span></a></div></div></div><section class="css-82r5pg css-1ub4i5m"></section></div></div></li><li class="css-12weawj"><div class="css-m260rd"><div class="css-1h1rean"><div class="css-1r7frvz"><div class="css-lm0pdr"><span style="font-size:0;line-height:0"></span><figure class="css-1e4ja14 css-f0t0lw"><a class="css-j5n0jw" data-event="engagement|bottom page content promo click|/health-news/cannabis-for-chronic-pain-linked-to-slightly-increased-risk-of-arrhythmia;engagement|bottom page content promo click index|7" data-element-event="INTERNAL LINK|FOOTER|Any Page|Read This Next|LINK|Cannabis for Chronic Pain Linked to Slightly Increased Risk of Arrhythmia|rn6" href="https://www.healthline.com/health-news/cannabis-for-chronic-pain-linked-to-slightly-increased-risk-of-arrhythmia?utm_source=ReadNext" aria-label="image-link" data-ga4="Read Next button clicks" data-testid="image-link" aria-hidden="true" tabindex="-1"><div class="css-79elbk"><span class="css-rwmw5v css-1pf0x3y"><span class="css-1767n2d"><lazy-image alt="Cannabis for Chronic Pain Linked to Slightly Increased Risk of Arrhythmia" src="https://media.post.rvohealth.io/wp-content/uploads/2022/08/cannabis-dispensary-732x549-thumbnail-732x549.jpg" srcSet="https://media.post.rvohealth.io/wp-content/uploads/2022/08/cannabis-dispensary-732x549-thumbnail-732x549.jpg 200w" className="css-1lyqwde"></lazy-image></span></span><span class="css-1fb1nmp"><span class="css-a10gts"></span></span></div></a></figure><div class="css-u8uhak"><a class="css-sqa1yu" data-event="engagement|bottom page content promo click|/health-news/cannabis-for-chronic-pain-linked-to-slightly-increased-risk-of-arrhythmia;engagement|bottom page content promo click index|7" data-element-event="INTERNAL LINK|FOOTER|Any Page|Read This Next|LINK|Cannabis for Chronic Pain Linked to Slightly Increased Risk of Arrhythmia|rn6" href="https://www.healthline.com/health-news/cannabis-for-chronic-pain-linked-to-slightly-increased-risk-of-arrhythmia?utm_source=ReadNext" data-testid="title-link" data-ga4="Read Next button clicks">Cannabis for Chronic Pain Linked to Slightly Increased Risk of Arrhythmia</a><p class=""><a class="css-onvglr" data-event="engagement|bottom page content promo click|/health-news/cannabis-for-chronic-pain-linked-to-slightly-increased-risk-of-arrhythmia;engagement|bottom page content promo click index|7" data-element-event="INTERNAL LINK|FOOTER|Any Page|Read This Next|LINK|Cannabis for Chronic Pain Linked to Slightly Increased Risk of Arrhythmia|rn6" href="https://www.healthline.com/health-news/cannabis-for-chronic-pain-linked-to-slightly-increased-risk-of-arrhythmia?utm_source=ReadNext" data-testid="text-link" data-ga4="Read Next button clicks" aria-hidden="true" tabindex="-1">People who use medical cannabis products for chronic pain may have a higher risk of heart rhythm disorders, or arrhythmias, according to preliminary…</a></p><a class="css-v5yzal css-ysgmro" data-event="engagement|bottom page content promo click|/health-news/cannabis-for-chronic-pain-linked-to-slightly-increased-risk-of-arrhythmia;engagement|bottom page content promo click index|7" data-element-event="INTERNAL LINK|FOOTER|Any Page|Read This Next|LINK|Cannabis for Chronic Pain Linked to Slightly Increased Risk of Arrhythmia|rn6" href="https://www.healthline.com/health-news/cannabis-for-chronic-pain-linked-to-slightly-increased-risk-of-arrhythmia?utm_source=ReadNext" data-ga4="Read Next button clicks">READ MORE<span class="icon-hl-arrow-right selector css-2kgwd5"></span></a></div></div></div><section class="css-82r5pg css-1ub4i5m"></section></div></div></li><li class="css-12weawj"><div class="css-m260rd"><div class="css-1h1rean"><div class="css-1r7frvz"><div class="css-lm0pdr"><span style="font-size:0;line-height:0"></span><figure class="css-1e4ja14 css-f0t0lw"><a class="css-j5n0jw" data-event="engagement|bottom page content promo click|/health-news/states-with-legalized-cannabis-have-fewer-synthetic-cannabinoid-poisonings;engagement|bottom page content promo click index|8" data-element-event="INTERNAL LINK|FOOTER|Any Page|Read This Next|LINK|States With Legalized Cannabis Have Fewer Synthetic Cannabinoid Poisonings|rn7" href="https://www.healthline.com/health-news/states-with-legalized-cannabis-have-fewer-synthetic-cannabinoid-poisonings?utm_source=ReadNext" aria-label="image-link" data-ga4="Read Next button clicks" data-testid="image-link" aria-hidden="true" tabindex="-1"><div class="css-79elbk"><span class="css-rwmw5v css-1pf0x3y"><span class="css-1767n2d"><lazy-image alt="States With Legalized Cannabis Have Fewer Synthetic Cannabinoid Poisonings" src="https://media.post.rvohealth.io/wp-content/uploads/2022/08/cannabis-shop-oregon-732x549-thumbnail-732x549.jpg" srcSet="https://media.post.rvohealth.io/wp-content/uploads/2022/08/cannabis-shop-oregon-732x549-thumbnail-732x549.jpg 200w" className="css-1lyqwde"></lazy-image></span></span><span class="css-1fb1nmp"><span class="css-a10gts"></span></span></div></a></figure><div class="css-u8uhak"><a class="css-sqa1yu" data-event="engagement|bottom page content promo click|/health-news/states-with-legalized-cannabis-have-fewer-synthetic-cannabinoid-poisonings;engagement|bottom page content promo click index|8" data-element-event="INTERNAL LINK|FOOTER|Any Page|Read This Next|LINK|States With Legalized Cannabis Have Fewer Synthetic Cannabinoid Poisonings|rn7" href="https://www.healthline.com/health-news/states-with-legalized-cannabis-have-fewer-synthetic-cannabinoid-poisonings?utm_source=ReadNext" data-testid="title-link" data-ga4="Read Next button clicks">States With Legalized Cannabis Have Fewer Synthetic Cannabinoid Poisonings</a><p class=""><a class="css-onvglr" data-event="engagement|bottom page content promo click|/health-news/states-with-legalized-cannabis-have-fewer-synthetic-cannabinoid-poisonings;engagement|bottom page content promo click index|8" data-element-event="INTERNAL LINK|FOOTER|Any Page|Read This Next|LINK|States With Legalized Cannabis Have Fewer Synthetic Cannabinoid Poisonings|rn7" href="https://www.healthline.com/health-news/states-with-legalized-cannabis-have-fewer-synthetic-cannabinoid-poisonings?utm_source=ReadNext" data-testid="text-link" data-ga4="Read Next button clicks" aria-hidden="true" tabindex="-1">New research shows a drop in synthetic cannabis poisonings in states that have legalized recreational cannabis. Synthetic cannabis products contain…</a></p><a class="css-v5yzal css-ysgmro" data-event="engagement|bottom page content promo click|/health-news/states-with-legalized-cannabis-have-fewer-synthetic-cannabinoid-poisonings;engagement|bottom page content promo click index|8" data-element-event="INTERNAL LINK|FOOTER|Any Page|Read This Next|LINK|States With Legalized Cannabis Have Fewer Synthetic Cannabinoid Poisonings|rn7" href="https://www.healthline.com/health-news/states-with-legalized-cannabis-have-fewer-synthetic-cannabinoid-poisonings?utm_source=ReadNext" data-ga4="Read Next button clicks">READ MORE<span class="icon-hl-arrow-right selector css-2kgwd5"></span></a></div></div></div><section class="css-82r5pg css-1ub4i5m"></section></div></div></li></ul></div></div></div><span class="css-zya54r"></span><span class="css-zya54r"></span></div><div class="css-i9gxme"></div><footer class="css-1dytfcg"><div class="css-1dppxl0"><hl-social-nav></hl-social-nav><div class="css-1b2ri56"><div class="css-uktbta css-ck5ydc"><hl-newsletter-cta buttonText="SIGN UP" source="footer_widget" subscribeEventTracking="Newsletter Acquisition|footer_widget|submit" className="css-13njx2h" category="Newsletter Acquisition" formatType="footer" name="footer_widget" productId="footer_widget" variant="footer_widget"></hl-newsletter-cta></div><div class="css-uktbta"><div class="css-1xceiwh"><div class="css-10ohy14"><ul class="css-lb03wr css-3o9pqj"><li class="css-34bq4y"><a class="css-1qz7cpo" href="https://www.healthline.com/about">About Us</a></li><li class="css-34bq4y"><a class="css-1qz7cpo" href="https://www.healthline.com/about/contact-us">Contact Us</a></li><li class="css-34bq4y"><a class="css-1qz7cpo" href="https://www.healthline.com/privacy-policy">Privacy Policy</a></li><li class="css-34bq4y"><button id="privacy-settings-one-trust" title="Privacy Settings" class="css-159kw12">Privacy Settings</button></li><li class="css-34bq4y"><a class="css-1qz7cpo" href="https://www.healthline.com/advertising-policy">Advertising Policy</a></li><li class="css-34bq4y"><a class="css-1qz7cpo" href="https://www.healthline.com/directory/topics">Health Topics</a></li></ul><ul class="css-lb03wr css-upe1zs"><li class="css-34bq4y"><a class="css-1qz7cpo" href="https://www.healthline.com/sitemap">Sitemap</a></li><li class="css-34bq4y"><a class="css-1qz7cpo" href="https://www.healthline.com/medical-team">Medical Affairs</a></li><li class="css-34bq4y"><a class="css-1qz7cpo" href="https://www.healthline.com/about/content-integrity">Content Integrity</a></li><li class="css-34bq4y"><a class="css-1qz7cpo" href="https://www.healthline.com/newsletter-signup">Newsletters</a></li><li class="css-34bq4y css-jwb353"><div class="css-16bllps css-1xdhyk6">© 2024 Healthline Media LLC. All rights reserved. Healthline Media is an RVO Health Company. Our website services, content, and products are for informational purposes only. Healthline Media does not provide medical advice, diagnosis, or treatment. <a class="css-1xx5q6 css-1081t4c" target="_blank" rel="noopener noreferrer" href="https://www.healthline.com/additional-information">See additional information</a>.</div></li></ul><div class="css-16bllps css-eqytyw">© 2024 Healthline Media LLC. All rights reserved. Healthline Media is an RVO Health Company. Our website services, content, and products are for informational purposes only. Healthline Media does not provide medical advice, diagnosis, or treatment. <a class="css-1xx5q6 css-1081t4c" target="_blank" rel="noopener noreferrer" href="https://www.healthline.com/additional-information">See additional information</a>.</div></div></div></div></div></div><div class="css-1us2gxx"><div class="css-11upubx"><a class="css-t5u34a" target="_blank" rel="nofollow" href="https://www.healthlinemedia.com/?utm_source=healthline.com&utm_medium=site&utm_campaign=footer&utm_content=logo" aria-label="Healthline Media Logo"><svg alt="Healthline Media" width="132" height="50" class="css-v23quv" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 132 50"><path fill="#FFF" d="M30.477 38.313v9.62h3.98V50h-6.36V38.313h2.38zm11.137 0v2.068h-2.548V50h-2.308v-9.62h-2.565v-2.067h7.421zm3.645 0v4.643h3.826v-4.643h2.337V50h-2.337v-4.976h-3.826V50h-2.32V38.313h2.32zm10.4 0v9.62h3.98V50h-6.362V38.313h2.381zm7.69 0V50h-2.12V38.313h2.12zm4.48 0 3.798 7.149v-7.149h2.325V50h-2.22l-3.955-7.447V50H65.47V38.313h2.359zm14.605 0v2.05h-4.13v2.681h4.013v2.032h-4.013v2.874h4.13V50h-6.362V38.313h6.362zm8.654 0 2.213 7.009 2.23-7.009h3.071V50h-2.264v-8.025L93.764 50h-.943l-2.54-8.025V50H88V38.313h3.088zm15.996 0v2.05h-4.13v2.681h4.014v2.032h-4.014v2.874h4.13V50h-6.361V38.313h6.361zm-104.764 0v4.643h3.825v-4.643h2.337V50H6.145v-4.976H2.32V50H0V38.313h2.32zm14.644 0v2.05h-4.13v2.681h4.013v2.032h-4.013v2.874h4.13V50h-6.362V38.313h6.362zm104.434 0V50h-2.12V38.313h2.12zm7.216-.065L132 49.935h-2.377l-.53-2.085h-3.728l-.53 2.085h-2.377l3.386-11.687h2.77zm-16.063 0c1.008 0 1.878.246 2.612.736.733.49 1.293 1.18 1.68 2.068.386.888.579 1.904.579 3.049 0 1.144-.19 2.158-.571 3.04-.381.882-.938 1.568-1.671 2.058-.734.49-1.61.736-2.629.736h-3.611V38.248h3.611zm-88.636 0 3.386 11.687h-2.377l-.53-2.085h-3.728l-.53 2.085h-2.377l3.386-11.687h2.77zm88.787 2.125h-1.377v7.437h1.377c.826 0 1.466-.339 1.92-1.018.452-.678.68-1.576.68-2.692 0-1.161-.224-2.073-.672-2.735-.448-.661-1.09-.992-1.928-.992zm14.394 0-1.457 5.578h2.915l-1.458-5.578zm-104.698 0-1.458 5.578h2.915l-1.457-5.578zM64.41.044c2.696-.128 2.3.047 3.785.227 3.92.477 7.448 3 9.744 6.016 1.679 2.204 1.893 4.935 1.835 7.58-.09 4.159-1.486 7.861-4.778 10.56-1.194.98-2.662 1.623-3.389 2.054-4.773 1.914-9.086 1.207-12.91-.525-2.566-1.16-4.286-3.257-5.25-5.988-.533-1.511-.81-3.018-1.112-4.588-.201-1.048-.1-2.166-.043-3.248.029-.556.254-1.101.393-1.65C54.11 4.863 58.62.32 64.411.043zm1.307 5.003-.046.01-6.204 2.374a.147.147 0 0 0-.067.222l.919 1.272v11.912c0 .081.065.146.146.146h5.259c.08 0 .146-.065.146-.146v-9.013a.395.395 0 0 1 .792 0v9.013c0 .081.065.146.146.146h5.936a.146.146 0 0 0 .131-.211l-.634-1.262v-5.668c0-3.283-2.62-3.74-4.185-3.74-1.043 0-1.859.366-2.186.61v-5.52a.146.146 0 0 0-.199-.136z"></path></svg></a><div class="css-d2oo9m"><div class="css-s2uf1z"><a class="css-s65yls" target="_blank" rel="nofollow" href="https://www.healthlinemedia.com/?utm_source=healthline.com&utm_medium=site&utm_campaign=footer&utm_content=about">About</a><a class="css-s65yls" target="_blank" rel="nofollow" href="https://rvohealth.com/careers">Careers</a><a class="css-s65yls" target="_blank" rel="nofollow" href="https://www.healthlinemedia.com/advertise?utm_source=healthline.com&utm_medium=site&utm_campaign=footer&utm_content=advertise">Advertise with us</a></div><div class="css-huujs8"><p class="css-1vtxghn">OUR BRANDS</p><a class="css-d9t9tq" rel="nofollow" href="https://www.healthline.com/">Healthline</a><a class="css-d9t9tq" target="_blank" rel="nofollow" href="https://www.medicalnewstoday.com/">Medical News Today</a><a class="css-d9t9tq" target="_blank" rel="nofollow" href="https://greatist.com/">Greatist</a><a class="css-d9t9tq" target="_blank" rel="nofollow" href="https://psychcentral.com/">Psych Central</a><a class="css-d9t9tq" target="_blank" rel="nofollow" href="https://bezzy.com/">Bezzy</a></div></div><a aria-label="@TRUST, AACI Certified logo" class="css-1c2ok3c css-1qsp2zb" href="https://aacihealthcare.com/certificates/c143-1-2021-trust-usa/" rel="noopener noreferrer nofollow" target="_blank"><div class="css-1vtpbs6"><lazy-image alt="This website is certified by AACI. Click to verify." src="//i0.wp.com/post.healthline.com/wp-content/uploads/2022/07/TRUST-Mark-1.png?" className="css-spwcx4"></lazy-image></div></a></div></div></footer><div id="foot-pad"></div><div id="consent-modal"></div></div><script> HL={"c":{"countryCode":"SG","countryNumber":702,"continentCode":"AS","dmaCode":"","hideConsumerHealthInformation":false,"consent":{"vendorListTcfVersion":5,"hasGlobalScope":false,"hasFullConsent":false,"gdprApplies":false,"tcString":false,"pingReturn":{},"tcData":{"gdprApplies":false,"cmpLoaded":true,"addtlConsent":"","eventStatus":"cmpuishown"}},"usPrivacyData":{"usprivacy":"1YNY","ccpaApplies":true},"isControl":false,"abSegment":"enableDatadogRUM=false;scrollIndicator=false;activationReadNext=true;adbDlbFix=false;experimentalRPM=variant;adbridgFlag=false;jwPlayerFix=true;dcsCopayBestOffer=control;dcsNativeCoupon=control;dcsCopayOnly=variant;adBlockerDetection=false;oneTrustCPRA=true;pathingTest=true;apscustomRemoval=false;showClusterNavMenu=true;traveler=variant;","abId":"3212f43a-ce92-473c-a31a-8a89a984c537","isNewId":true,"abTestUrls":{"moveImageGalleryBelowH2":["/health/drugs/trulicity","/health/drugs/spiriva","/health/drugs/januvia","/health/drugs/olumiant","/health/drugs/trintellix","/health/drugs/zetia","/health/drugs/lybalvi","/health/drugs/sunosi","/health/drugs/nplate","/health/drugs/nexplanon","/health/drugs/leqvio","/health/drugs/taltz","/health/drugs/repatha","/health/drugs/venclexta","/health/drugs/nucala"],"prerollAdRule":["/nutrition/9-benefits-oats-oatmeal"],"postrollAdRule":["/health/fitness/weight-bench","/nutrition/best-punching-bag","/nutrition/protein-for-vegans-vegetarians","/nutrition/can-you-drink-rain-water"],"expandedTableOfContents":["/health/exercise-fitness/postnatal-exercises","/nutrition/red-clover","/health/baby/baby-banging-head","/health/bump-on-big-toe","/health/yellow-tongue","/health/onion-juice-for-hair","/nutrition/vegan-bodybuilding-diet","/health/skin-tear","/health/beauty-skin-care/is-soap-bad-for-skin","/health/perineum-pain","/health/sleeping-without-a-pillow","/health/scalp-yeast-infection","/health/how-to-shower","/health/pregnancy/what-causes-rashes-during-pregnancy-and-how-to-treat-them","/health/pregnancy/rib-pain","/health/heel-pain-in-the-morning","/health/baby/how-often-do-normal-couples-have-sex","/health/how-to-avoid-sleepiness-while-studying","/nutrition/banaba-leaf","/health/beauty-skin-care/hard-pimple","/health/womens-health/menstrual-cycle-and-the-moon","/health/pregnancy/babies-born-at-36-weeks","/health/adderall-effects-on-brain","/health/how-to-get-rid-of-pimple-scabs","/health/self-massage","/nutrition/soaking-almonds","/health/shaking-after-workout","/health/oat-allergy","/health/chalazion-surgery","/health/constipation-during-period","/health/cold-flu/cold-flu-secrets","/health/baby/baby-red-around-eyes","/health/pregnancy/signs-of-having-a-boy","/health/lines-under-eyes","/health/how-to-get-a-thicker-neck","/health/pregnancy/no-morning-sickness","/health/bone-health/the-4-main-types-of-posture","/health/positions-to-help-period-cramps","/health/how-to-regulate-periods","/health/eye-health/20-20-20-rule","/nutrition/greasy-food","/nutrition/copper-water-benefits","/health/itchy-forearms","/health/es/vitaminas-para-ojos-secos","/health/post-vacation-blues","/health/erectile-dysfunction/can-masturbation-cause-erectile-dysfunction","/health/meningitis-pictures-rash-symptoms","/health/postpartum-cramps","/health/acne-between-eyebrows","/health/throwing-up-blood-after-drinking","/health/gerd/gas","/health/bubble-bath-soaps","/health/herpes-esophagitis","/health/sunburned-scalp","/health/boron-testosterone","/health/birth-control/can-i-change-the-time-i-take-my-birth-control","/health/presyncope","/health/flu-symptoms","/health/urination-excessive-volume","/health/average-shoe-size-for-women","/health/beauty-skin-care/laser-treatment-for-acne-scars","/nutrition/black-eyed-peas-nutrition","/health/what-you-need-to-know-about-dental-crowns-made-from-zirconia","/nutrition/keratin-rich-foods","/health/exercise-fitness/what-to-do-after-working-out","/health/mango-fly","/nutrition/indian-gooseberry","/health/fitness-nutrition/poppy-seeds-drug-test","/health/flying-with-ear-infection","/health/womens-health/crying-during-period","/health/sweet-smelling-urine","/health/fell-down-the-stairs","/health/parenting/toddler-congestion-remedies","/health/treat-pimple-on-neck","/health/chondrodermatitis-nodularis-helicis","/health/how-to-prevent-split-ends","/health/body-modification/tattoo-blowout","/health/postpartum-diet","/health/diabetes/costus-igneus-side-effects","/health/pregnancy/pregnancy-mood-swings","/health/bruised-knuckles","/health/womens-health/why-does-my-breast-hurt-when-i-press-it","/health/baby/dropped-baby","/health/soft-wax-vs-hard-wax","/nutrition/what-to-eat-after-running","/health/exercise-fitness/never-skip-leg-day","/health/breastfeeding/how-to-combine-breastfeeding-and-pumping","/health/stomach-cramps-in-men","/health/sinus-rinse-dangers","/health/get-rid-of-scars-on-legs","/health/ciu/foods-to-eat-and-avoid","/health/beauty-skin-care/over-exfoliating","/health/dental-and-oral-health/tongue-sucking","/health/mens-health/bleeding-from-penis","/health/i-lost-weight-after-abortion","/health/calcium-deposits-on-skin","/health/bradypnea","/health/types-of-feet","/health/uneven-lips","/health/coagulation-tests","/health/erectile-dysfunction/surprising-facts","/health/pregnancy/third-trimester-nausea","/health/mental-health/nervous-laughter","/health/seated-row","/health/how-to-reduce-melanin","/health/headache-after-running","/health/anxiety/subconscious-anxiety","/health/why-smoking-reclaimed-cannabis-resin-isnt-a-good-idea","/nutrition/what-to-put-in-oatmeal","/health/baby/cleaning-babys-nose","/health/pregnancy/hidden-twin-ultrasound","/health/infected-mole","/health/pregnancy/ear-infection-while-pregnant","/health/endotough/period-symptoms-not-to-ignore","/health/cic/what-your-gut-is-trying-to-tell-you","/health/parenting/breastfeeding-lump","/health/skinned-knee","/health/scab-in-ear","/health/pineal-gland-dmt","/nutrition/foods-that-cause-blood-in-stool","/health/pregnancy/butt-pain","/health/withdrawal-bleeding","/health/white-pubic-hair","/health/pelvic-pain-in-men","/health/beauty-skin-care/how-to-get-shiny-hair","/health/cutis-marmorata","/health/mens-health/smelly-penis","/health/mens-health/pain-in-right-testicle-and-inner-thigh","/health/dental-and-oral-health/cut-on-gums","/health/scabies-on-the-penis","/health/hairy-butt-crack","/health/how-to-get-rid-of-smegma","/health/pimple-on-nipple","/health/canker-sore-on-tonsil","/health/fertility/how-to-inject-hcg","/health/beauty-skin-care/should-you-pop-a-pimple","/health/es/moco-en-las-heces","/health/food-grade-hydrogen-peroxide","/health/mental-health/tired-from-work","/health/skin-tag-on-tongue","/health/wound-dehiscence","/health/dental-and-oral-health/black-triangles-teeth","/health/hairy-nipples","/health/fitness/pull-ups-everyday","/health/ear-blowout","/health/pregnancy/soda-during-pregnancy","/health/pregnancy/toothpaste-pregnancy-test","/health/pregnancy/pcos-and-pregnancy-test","/health/beauty-skin-care/double-crown-hair","/health/hiv-aids/cd4-viral-count","/health/do-cortisone-shots-work-for-acne","/health/itchy-throat-covid","/nutrition/sole-water","/nutrition/apetamin","/health/parenting/cracked-nipples","/health/tranexamic-acid-side-effects","/health/mental-health/eating-dirt","/health/elisa","/health/es/pan-para-diabeticos","/health/am-i-lesbian","/health/relationships/breadcrumbing","/nutrition/maca-root-for-curves","/health/aloe-vera-for-acne","/nutrition/galangal-root","/health/fear-of-intimacy","/health/whitehead","/health/childrens-health/baby-acne","/health/substance-use/smoking-mdma","/nutrition/foods/wheat","/health/pregnancy/how-to-get-pregnant-with-pcos","/health/es/diabetes-tipo-2-y-piel","/health/saggy-balls","/health/fitness/deadlift-benefits","/health/pregnancy/what-medicines-are-safe-during-pregnancy","/health/birth-control/missed-one-birth-control-pill-can-i-get-pregnant","/health/infection/cephalexin-alcohol","/health/testicle-lump","/health/birth-control/i-accidentally-took-2-birth-control-pills-in-one-day","/health/es/palpitaciones-en-el-corazon-por-la-noche","/health/pimple-in-throat","/health/penis-fish","/health/mens-health/hairy-penis","/health/birth-control/missed-one-pill-and-had-unprotected","/health/rust-on-skin","/health/mens-health/penis-irritation","/health/erectile-dysfunction/horny-goat-weed","/health/freebasing","/health/masturbation-effects-on-kidney","/health/transgender/tucking","/health/high-blood-pressure-hypertension/during-pregnancy","/health/hydrocortisone-for-acne","/health/pregnancy-after-vasectomy","/health/pregnancy/how-to-prepare-your-body","/health/es/escamacion-de-las-yemas-de-los-dedos","/health/breastfeeding/nipple-biting","/health/how-to-make-your-nose-smaller","/health/exercise-for-nose","/health/pregnancy/bloody-stool-pregnancy","/health-news/how-you-can-die-from-caffeine","/health/womens-health/ovarian-cyst-treatment-at-home","/health/skin-allergy-home-remedy","/health/pregnancy/evaporation-line-pregnancy-test","/health/biliary-colic","/health/drinking-bleach","/health/breastfeeding/breastfeeding-and-antibiotics","/health/anxiety-sore-throat","/health/pms-mood-swings","/health/hamstring-curls","/health/high-pain-tolerance","/health/exercise-to-gain-weight","/nutrition/oatmeal-alternatives","/health/ear-stretching","/nutrition/working-out-while-sick","/health/beauty-skin-care/vaseline-on-lips","/health/exercise-fitness/cooldown-exercises","/health/pregnancy/2-vessel-cord","/health/acne-keloidalis-nuchae","/nutrition/cherimoya","/health/baby/how-to-clean-baby-tongue","/health/baby/baby-acne-breast-milk","/health/24-hour-urine-protein","/health/eye-health/mucus-fishing-syndrome","/health/mens-health/thrush-in-men","/health/jojoba-oil-for-hair","/health/armpit-pimple","/health/jumping-rope-to-lose-weight","/health/es/sangre-en-las-heces","/health/why-do-i-talk-to-myself","/health/homeopathy-for-anxiety","/health/fitness/how-to-build-strength-guide","/health/pimple-that-won-t-go-away","/health/beauty-skin-care/no-poo","/health/scapular-winging","/health/relationships/one-sided-relationship","/health/pregnancy/ring-gender-test","/health/baby/baby-wont-nap","/health/tooth-sensitive-to-hot-and-cold","/health/dental-and-oral-health/transparent-teeth","/health/fitness/squats-for-glutes","/health/home-remedies-for-gonorrhea","/health/ingrown-toenail-infection","/health/womens-health/do-your-breasts-hurt-when-they-grow","/health/childrens-health/angry-toddler","/health/pregnancy/hot-pregnant","/health/moldy-weed","/nutrition/ayurvedic-herbs","/health/pregnancy/pregnant-and-horny","/health/pregnancy/how-long-does-hcg-stay-in-your-system","/health/cold-sore-triggers","/health/how-to-decrease-libido","/nutrition/loss-of-appetite-pregnancy","/health/antibiotics/antibiotics-and-weed","/health/asymmetrical-face","/health/leg-press-alternative","/health/tonsillectomy-scabs","/health/sacralization","/health/benefits-of-playing-chess","/health/betel-nut-dangers","/nutrition/ginger-for-sex","/health/dark-line-on-stomach-not-pregnant","/health/pregnancy/ovary-pain-early-pregnancy","/health/sore-throat-after-drinking","/health/beauty-skin-care/pockmarks","/health/how-to-stretch-foreskin","/health/beauty-skin-care/almond-oil-for-face","/health/chemically-castrating","/health/how-to-get-rid-of-redness-from-pimples","/health/womens-health/light-headed-during-period","/health/blood-group-compatibility-for-marriage","/health/oral-rehydration-solution","/health/period-flu","/health/exercise-fitness/average-10k-time","/health/recurring-thrush","/health/baby/how-to-cut-baby-hair","/health/male-discharge-normal","/health/how-to-be-charismatic","/health/pregnancy/loose-skin-postpartum","/health/pregnancy/skull-theory","/health/arrhythmia/drugs","/health/blue-toenails","/health/melanin-in-hair","/health/feels-hot-to-touch","/health/baby/eruption-cyst-baby","/health/beauty-skin-care/deep-blackheads","/health/birth-control/cramps-on-birth-control","/health/hiv-aids/symptoms-men","/health/angiokeratoma","/health/left-arm-pain-anxiety","/health/cauterizing-a-wound","/health/abdominal-pain-and-breast-tenderness","/health/medications-workouts-do-not-mix","/health/oily-nose","/health/pilonidal-cyst-surgery","/nutrition/carom-seeds","/health/pregnancy/how-to-increase-amniotic-fluid","/health/womens-health/period-changes-20s-30s-40s-50s","/health/fitness/drinking-after-workout","/health/big-testicles","/health/signs-of-pregnancy-while-on-birth-control","/health/chest-pain-and-diarrhea","/health/can-you-get-high-from-smelling-weed","/health/es/como-dormir-con-tos","/health/mens-health/testicular-retraction","/health/exercise-fitness/running-on-an-empty-stomach","/health/delayed-growth-symptom","/health/dizzy-when-blowing-nose-ears-popping","/health/crown-of-head","/health/relactation","/health/es/funciona-la-biotina-para-el-crecimiento-del-cabello","/health-news/does-jawzrsize-really-work","/health/signs-that-someone-is-using-crystal-meth","/health/saliva-blood","/health/rashes-from-pads","/health-news/can-ice-baths-help-you-burn-body-fat-new-research-says-yes","/health/chest-and-neck-pain","/health/the-causes-of-overlapping-toes-and-treatment-options","/health/headache-after-exercise","/health/growing-pains-in-adults","/health/es/tipos-de-caca","/health/mens-health/one-testicle-bigger-than-the-other","/health/hypertrophic-scar-piercing","/health/exercise-fitness/16-dumbbell-exercises-for-abs","/health/gingival-hyperplasia","/health/beauty-skincare/thin-skin-under-eyes","/nutrition/sour-foods","/health/birth-control/how-to-avoid-pregnancy","/health/fitness-exercise/push-ups-for-biceps","/health/double-penetration","/health/laser-carbon-peel","/health/toasted-skin-syndrome","/health/mens-health/painful-ejaculation","/health/pregnancy/mucus-plug-early-pregnancy","/health/baby/dehydration-in-babies","/health/tinea-manuum","/health/birth-control/late-period-after-stopping-birth-control","/health/ulcers-in-babys-mouth","/nutrition/tomato-juice","/health/womens-health/endometriosis-leg-pain","/health/eye-health/greyish-spot-on-white-of-eye","/health/birth-control/weight-loss-after-iud-removal","/health/penis-pain","/health/parenting/breastfed-poop","/health/colloidal-silver","/health/baby/white-curds-in-baby-poop","/health/es/monocitos-altos","/health/pregnancy/implantation-calculator","/health/pimple-pus","/health/what-is-sandalwood","/health/addiction/sex","/health/daytime-sleepiness/tips-for-work","/health/tongue-piercing-healing-stages","/health/adhd/supplements","/health/blood-culture","/health/high-libido","/health/itchy-acne","/health/what-are-blemishes","/nutrition/a1-vs-a2-milk","/nutrition/foods/beef","/health/fitness-exercise/karate-vs-taekwondo","/health/baby/baby-rubbing-eyes","/health/fitness-exercises/better-sex-workout","/health/how-to-get-gum-out-of-hair","/health/womens-health/effective-yeast-infection-remedies","/nutrition/weight-loss-diet-plan-for-men","/health/womens-health/how-many-days-between-periods","/health/pregnancy/implantation-cramping","/health/substance-use/coke-bloat","/health/beauty-skin-care/shampoo-or-conditioner-first","/nutrition/bananas-with-milk","/health/shortness-of-breath-early-pregnancy","/health/retinol-for-acne","/health/pregnancy/pregnancy-symptoms-week-10","/health/types-of-relationships","/health/birth-control/starting-birth-control-mid-cycle","/nutrition/what-is-arrowroot","/nutrition/yam-benefits","/nutrition/spirulina-side-effects","/health/hydrocele","/health/mens-health/average-testicle-size","/health/beauty-skin-care/honey-and-lemon-for-face","/health/can-you-take-a-bath-on-period","/health/pregnancy/third-trimester-pain-insomnia","/nutrition/tahini-benefits","/health/pregnancy/crying-during-pregnancy","/health/substance-use/lsd-vs-shrooms","/nutrition/turmeric-benefits-weight-loss","/nutrition/arnica-homeopathic","/health/stiff-back","/health/low-cheekbones-vs-high-cheekbones","/health/female-sexual-arousal-disorder","/health/mens-health/left-testicle-pain","/health/how-long-do-hickeys-last","/health/unconsciousness-first-aid","/health/mens-health/irritable-male-syndrome","/health/sexual-coercion","/health/does-masturbation-increase-blood-pressure","/health/sloped-shoulders","/health/pus-in-ear","/health/heimlich-maneuver","/health/birth-control/how-long-is-too-long-to-be-on-birth-control"],"collapsedTableOfContents":[],"livedExperienceMVP":["/health/regrow-hair-naturally","/health/cold-flu/sore-throat-natural-remedies","/nutrition/13-acne-remedies","/health/natural-ways-to-reduce-anxiety","/nutrition/zinc-supplements","/health/losing-a-parent","/health/does-rogaine-work","/health/food-nutrition/best-vitamins-to-take-daily","/nutrition/do-multivitamins-work","/nutrition/pre-workout-supplements","/nutrition/best-cooking-oils","/health/sunscreen-for-oily-skin","/nutrition/best-gluten-free-bread","/health/beauty-skin-care/best-sunscreens-for-dark-skin","/health/best-natural-shampoo","/health/thrive-market-review","/nutrition/best-testosterone-booster-supplements","/health/pregnancy/best-breast-pump","/nutrition/metabolic-renewal-reviews","/nutrition/best-weight-gain-supplements","/nutrition/best-snacks-for-diabetes","/nutrition/best-foods-for-constipation","/health/high-bilirubin","/nutrition/foods-to-avoid-with-kidney-disease-and-diabetes","/health/mental-health/how-to-cope-with-anxiety","/health/natural-ways-to-reduce-migraines","/health/diabetes","/health/high-cortisol-symptoms","/health/high-blood-pressure-home-remedies","/health/anxiety/anxiety-nausea","/health/osteoarthritis/arthritis-natural-relief","/health/hormonal-imbalance","/health/how-to-stop-ruminating","/health/cold-flu/how-to-get-rid-of-phlegm","/nutrition/6-proven-health-benefits-of-apple-cider-vinegar"],"reducedFontSize":["/health/womens-health/vaginal-boils","/health/how-to-get-rid-of-sinus-infection","/health/womens-health/safe-period","/health/shingles-contagious","/nutrition/ginseng-benefits","/health/es/erupcion-cutanea","/health/food-nutrition/what-to-eat-after-food-poisoning","/health/how-to-stop-being-high","/health/eft-tapping","/nutrition/dragon-fruit","/nutrition/6-benefits-of-oil-pulling","/nutrition/10-signs-and-symptoms-of-ketosis","/health-news/the-real-housewives-of-new-jersey-star-dolores-catania-lost-20-pounds-taking-ozempic-mounjaro","/health/crohns-disease/would-get","/health/fitness/back-strengthening-muscles-posture","/health/home-remedies-for-warts","/nutrition/avocado-nutrition","/health/pain-on-top-of-the-foot","/health/how-long-does-acid-last","/health/womens-health/one-day-period","/health/es/remedios-caseros-para-los-calculos-renales","/health/mens-health/pe-home-remedies","/health/pain-in-back-of-head","/health/sore-eye-remedies","/health/nofap-benefits","/health/es/alivio-del-dolor-de-la-vesicula-biliar","/health/grounding","/health/exercise-fitness/lower-ab-workouts","/nutrition/low-carb-diet-meal-plan-and-menu","/health/food-stuck-in-throat","/nutrition/eat-after-workout","/nutrition/best-fish-oil-supplement","/health/pebble-poop","/nutrition/dandelion-benefits","/health/dizziness-and-fatigue","/health/gerd/diet-nutrition","/nutrition/foods-loaded-with-potassium","/health/how-to-stop-loving-someone","/nutrition/vitamin-c-foods","/health/dental-and-oral-health/sore-tongue","/health/inner-knee-pain","/health/mosquito-bite-blister","/health/healthy-sex/what-are-butt-plugs-used-for","/nutrition/8-benefits-of-kombucha-tea","/health/how-to-tan-faster","/health/mosquito-blood-type","/health/baby/baby-hit-head","/nutrition/get-rid-of-pimples-fast","/health/best-scar-cream","/health/cold-flu/home-remedies-for-dry-cough","/nutrition/lean-protein-foods","/health/baby/why-cant-babies-have-water","/health/how-to-stop-sweating-face","/health/home-remedies-for-itchy-scalp","/nutrition/best-vitamin-brands","/nutrition/ways-to-tell-if-ground-beef-is-bad","/health/how-to-stop-a-panic-attack","/nutrition/9-foods-to-help-you-sleep","/health/es/como-quitar-la-congestion-nasal","/nutrition/10-benefits-of-creatine","/health/sexually-transmitted-diseases/home-remedies-for-herpes","/nutrition/aloe-vera-juice-benefits","/health/snot-color","/nutrition/carnivore-diet","/health/best-protein-powder","/nutrition/10-baking-powder-substitutes","/nutrition/saffron","/health/shoulder-pain-exercises","/health/toxic-relationship","/health/es/superior-izquierda-dolor-abdominal-bajo-costillas","/health/es/como-quitar-las-ganas-de-vomitar","/health/es/remedios-caseros-para-el-dolor-de-estomago","/nutrition/foods-high-in-soluble-fiber","/health/home-remedies-for-tonsilitis","/health/skin-disorders/red-bumps-on-legs","/nutrition/zero-calorie-foods","/health/iron-infusion","/health/beauty-skin-care/niacinamide","/health/skin/tretinoin","/nutrition/apple-cider-vinegar-side-effects","/nutrition/healthiest-beans-legumes","/health/home-remedies-for-abscess-tooth","/health/digestive-health/diarrhea-after-eating","/health/digestive-health/most-effective-diarrhea-remedies","/nutrition/6-ways-to-do-intermittent-fasting","/health/poop-stuck-halfway-out","/nutrition/benefits-of-walnuts","/health/gut-health","/nutrition/12-proven-benefits-of-pomegranate","/nutrition/best-protein-bars","/health/es/dolor-en-la-espalda-el-lado-derecho-inferior","/health/vulva-vagina-products","/nutrition/foods-with-estrogen","/health/healthy-sex/lube-shopping-guide-types","/nutrition/top-10-evidence-based-health-benefits-of-coconut-oil","/health/gallbladder-pain-relief","/health/adhd/adult-adhd","/nutrition/vitamin-k2","/nutrition/sleep-aids","/health/healthy-home-guide/how-to-get-rid-of-fleas"],"affiliateDisclaimer":["/health/broad-spectrum-cbd","/health/womens-health/garden-of-life-reviews","/health/social-cbd","/health/spruce-cbd-review","/health/air-purifier-for-smoke","/health/massage-chair-pads","/health/ecg-monitor","/health/best-blood-pressure-monitor-watches","/nutrition/best-exercise-bike-for-home","/nutrition/fitness-trackers-for-women","/nutrition/peloton-bike-alternatives","/nutrition/best-elliptical","/health/best-fit-test","health/acupressure-mat","health/best-thermometer","/health/dental-and-oral-health/best-teeth-whitening","/health/costco-hearing-aids","/health/lively-hearing-aids","/nutrition/best-multivitamin-for-men-over-50","/health/regrow-hair-naturally","/health/erectile-dysfunction/medication-list","/health/erectile-dysfunction/viagra-alternative","/health/talkspace-reviews","/nutrition/meal-delivery-for-seniors","/nutrition/trifecta-meals","/nutrition/best-protein-bars","/health/parenting/best-toddler-pillows","/health/parenting/toys-for-kids-with-autism","/health/beauty-skin-care/best-vitamin-c-serum","/health/pregnancy/best-stretch-mark-creams-for-pregnancy","/health/beauty-skin-care/best-eye-cream-for-dark-circles","/health/healthy-sleep/best-full-size-mattress","/health/healthy-sleep/best-eucalyptus-sheets","/health/healthy-sleep/split-king-mattress","/health/best-earplugs-for-sleeping","/health/glasses-online","/health/blue-light-glasses-for-kids","/nutrition/care-of-vitamins","/nutrition/olly-vitamins-review","/health/pure-vitamins"],"affiliateDisclaimer2":["/cbd/top-cbd-brands","/cbd/best-cbd-cream-for-pain","/cbd/best-cbd-for-sleep","/cbd/best-cbd-gummies","/cbd/best-cbd-gummies-for-anxiety","/cbd/the-best-cbd-gummies-for-pain","/cbd/best-cbd-oil","/cbd/strongest-cbd-gummies","/nutrition/best-creatine","/health/online-cialis","/health/mens-health/generic-viagra","/health/hims-ed-review","/health/hims-vs-roman","/health/mens-health/viagra-online","/health/therapy-for-every-budget","/health/mental-health/betterhelp-review","/health/mental-health/online-therapy-that-takes-insurance","/nutrition/best-meal-delivery-service","/nutrition/best-prepared-meal-delivery-service","/nutrition/buy-ozempic-online","/nutrition/how-to-get-wegovy","/nutrition/ro-review","/nutrition/best-multivitamins-for-men","/nutrition/multivitamins-womens-health","/health/pregnancy/best-prenatal-vitamins","/nutrition/best-probiotic-supplement","/health/food-nutrition/best-probiotics-women","/nutrition/buy-zepbound-online","/cbd/cbd-gummies-for-sleep","/health/cornbread-hemp","/health/strongest-cbd-oil","/health/at-home-std-test","/health/mens-health/bluechew-vs-hims","/health/hair-growth-products","/health/roman-ed-review","/health/our-top-10-online-therapy-picks","/health/mental-health/online-therapy-for-teens","/nutrition/factor-75","/nutrition/weight-loss-meal-delivery","/health/drugs/wegovy-prescription-online","/health/best-cbd-oil-for-anxiety","/nutrition/best-fish-oil-supplement","/nutrition/best-vitamin-brands","/health/birth-control/birth-control-online","/health/cbd-oil-for-joint-pain","/health/mens-health/male-enhancement-pills","/health/mental-health/online-psychiatrist","/health/vitamin-deficiency-test","/cbd/cbd-for-stress","/health/uti-home-remedies","/nutrition/best-mass-gainer","/nutrition/best-heart-rate-monitoring-watch","/nutrition/best-vegan-protein-powder-review","/nutrition/buy-mounjaro-online","/health/hair-loss-treatments-for-men","/nutrition/best-protein-powders-for-weight-loss","/nutrition/best-magnesium-supplement","/nutrition/vitamins-for-kids","/health/healthy-sex/free-sti-testing","/health/ed-pills-online","/health/healthy-sex/how-to-get-harder-erections","/health/drugs/ozempic-alternatives","/cbd/best-cbd-capsule","/health/full-spectrum-cbd","/health/full-spectrum-cbd-tincture","/health/thc-free-cbd-oil","/nutrition/diabetic-meal-delivery","/health/hormone-test-at-home","/health/thyroid-at-home-test","/health/mental-health/online-sex-therapy","/health/testosterone-test-kits","/health/viagra-price","/health/mental-health/online-therapist-for-free","/nutrition/cheapest-meal-delivery-service","/nutrition/gluten-free-meal-delivery","/nutrition/healthy-meal-delivery","/nutrition/keto-meal-delivery","/nutrition/best-mediterranean-diet-meal-delivery","/nutrition/organic-meal-delivery","/nutrition/plant-based-meal-delivery","/nutrition/athletic-greens-review","/nutrition/personalized-vitamins","/health/cortisol-tests","/health/bluechew-vs-roman","/nutrition/best-weight-loss-apps","/health/food-sensitivity-test","/nutrition/how-to-get-mounjaro","/nutrition/how-to-get-zepbound","/nutrition/best-multivitamin-for-women-over-50","/nutrition/creatine-for-women","/health/menopause/menopause-home-test","/health/mens-health/keeps-vs-hims","/health/nutrafol-reviews","/cbd/best-cbd-for-arthritis-pain","/health/top-10-cbd-lotions-creams-and-topicals","/cbd/cheap-cbd-oil","/health/everlywell-review","/health/erectile-dysfunction/otc","/nutrition/best-weight-loss-programs","/nutrition/weight-loss-medication","/nutrition/best-iron-supplement","/nutrition/best-vitamin-d-supplements","/health/cbd-for-energy","/health/best-protein-powder","/nutrition/best-greens-powder","/health/erectile-dysfunction/cialis-levitra-viagra","/health/digestive-health/whats-the-best-fiber-supplement","/health/cbdfx","/health/mental-health/therapy-for-kids","/nutrition/best-body-fat-scale","/health/pregnancy/best-breast-pump","/nutrition/best-turmeric-supplements","/nutrition/best-vitamin-b-supplement","/nutrition/best-vitamins-hair-growth","/health/womens-health/hers-review","/health/healthy-sleep/cloud-mattress","/health/fitness-exercise/best-dumbbells","/health/parenting/best-postpartum-hair-products","/health/pregnancy/best-stretch-mark-creams-for-pregnancy","/nutrition/seed-probiotics-review","/health/std-treatment-online","/nutrition/best-hair-skin-and-nails-vitamins","/health/birth-control/where-to-get-plan-b","/health/optum-viagra","/nutrition/low-carb-protein-powders","/health/best-knee-compression-sleeves","/health/best-stethoscopes","/nutrition/best-protein-bars","/health/erectile-dysfunction/medication-list","/health/generic-cialis","/health/drugs/mounjaro-for-weight-loss","/health/4-supplements-as-powerful-as-drugs","/health/decolletage","/health/grounding","/health/beauty-skin-care/nose-pores","/health/how-to-use-kegel-balls","/health/baby/baby-rolling-over-in-sleep","/health/butt-sweat","/health/thinning-hair","/health/boost-your-libido-10-natural-tips","/health/shampoo-seborrheic-dermatitis","/health/fitness-exercise/pool-exercises","/health/broken-tailbone","/health/anxiety/social-anxiety-treatment","/health/beauty-skin-care/how-to-get-rid-of-large-pores","/health/pregnancy/padsicles","/health/low-testosterone/warning-signs","/health/drugs/wegovy-cost","/health/anal-douche","/health/how-to-find-out-your-blood-type","/health/low-porosity-hair","/health/what-is-a-cock-ring-used-for","/health/mthfr-gene","/health/healthy-sex/anal-sti-test","/health/parenting/toddler-yeast-infection","/health/what-is-a-metabolism-test-and-can-you-use-it-for-weight-loss-and-fitness","/health/hip-pain-at-night","/health/allergic-to-bandaids","/health/beauty-skin-care/how-to-use-hyaluronic-acid","/health/cbd-for-insomnia","/health/erectile-dysfunction","/health/erectile-dysfunction/ed-pills","/nutrition/do-collagen-supplements-work","/nutrition/collagen","/health/hair-loss-prevention","/health/cbd-oil-for-pain","/health/erection-problems","/health/how-long-does-cbd-stay-in-your-system","/health/erectile-dysfunction/can-masturbation-cause-erectile-dysfunction","/health/erectile-dysfunction/young-men","/health/erectile-dysfunction/surprising-facts","/health/cbd-for-anxiety","/nutrition/how-much-collagen-per-day","/health/womens-health/yeast-infection-home-remedy","/nutrition/collagen-benefits","/health/nerve-pain-medication-over-the-counter","/health/sore-after-massage","/health/how-to-delay-period-naturally","/health/swollen-eyes-from-crying","/health/depression/morning-depression"],"contentClusterInfiniteScroll":["/health/osteoarthritis-symptoms","/health/osteoarthritis/crepitus","/health/cracking-shoulder","/health/osteoarthritis/heberdens-nodes","/health/early-symptoms-osteoarthritis","/health/osteoarthritis/osteoarthritis-flare-up","/health/osteoarthritis-pictures","/health/osteoarthritis/osteoarthritis-hip-x-ray","/health/osteoarthritis/what-does-arthritis-look-like-on-an-mri","/health/osteoarthritis/oa-of-the-knee-xray","/health/osteoarthritis/tricompartmental-osteoarthritis","/health/osteoarthritis/big-toe","/health/subchondral-sclerosis","/health/osteoarthritis/what-is-erosive-osteoarthritis","/health/glenohumeral-osteoarthritis","/health/osteoarthritis/osteoarthritis-hand","/health/sacroiliitis","/health/osteoarthritis-spine","/health/bilateral-knee-osteoarthritis","/health/rapid-destructive-hip-osteoarthritis","/health/osteoarthritis/medial-compartmental-osteoarthritis","/health/posttraumatic-osteoarthritis","/health/osteoarthritis/osteoarthritis-shoulder","/health/osteoarthritis/hypertrophic-osteoarthropathy","/health/osteoarthritis/knee/osteoarthritis-of-the-knee","/health/osteoarthritis-treatment","/health/osteoarthritis/arthritis-hand-exercises","/health/osteoarthritis/platelet-rich-plasma-knee","/health/osteoarthritis/hip-treatments","/health/chiropractor-for-hip-pain","/health/osteoarthritis/knee-injections-for-osteoarthritis","/health/osteoarthritis/over-counter-relief","/health/osteoarthritis/medications-list","/health/types-of-osteoarthritis-braces","/health/osteoarthritis/synvisc-vs-hyalgan","/health/osteoarthritis/total-hip-replacement","/health/regenokine","/health/osteoarthritis/treatment-options-for-delaying-knee-surgery","/health/osteoarthritis/qa-treatments","/health/total-knee-replacement-surgery/rehabilitation-timeline","/health/total-knee-replacement-surgery/managing-postoperative-pain","/health/knee-replacement-infection","/health/knee-replacement-surgery","/health/total-knee-replacement-surgery/surgical-options","/health/total-knee-replacement-surgery-step-by-step","/health/total-knee-replacement-surgery/medications","/health/total-knee-replacement-surgery/sports-activities-after","/health/total-knee-replacement-surgery/insomnia-depression","/health/total-knee-replacement-surgery/risks-complications","/health/total-knee-replacement-surgery/understanding-costs","/health/total-knee-replacement-surgery/outcomes-statistics-success-rate","/health/total-knee-replacement-surgery/common-questions","/health/preparing-your-home-knee-replacement-recovery","/health/knee-replacement-artificial-joints-versus-natural","/health/total-knee-replacement-surgery/expectations","/health/total-knee-replacement-surgery/implant-manufacturers","/health/total-knee-replacement-surgery-daily-life","/health/total-knee-replacement-surgery","/health/after-total-knee-replacement-surgery","/health/total-knee-replacement-surgery/when","/health/total-knee-replacement-surgery/orthopedic-evaluation","/health/total-knee-replacement-surgery/follow-up-appointments","/health/common-causes-osteoarthritis","/health/osteoarthritis-stages-of-oa-of-the-knee","/health/osteoarthritis/advanced-osteoarthritis","/health/osteoarthritis/complications-and-dangers","/health/osteoarthritis/knee-pain/link-between-weight-loss-and-knee-pain","/health/covid-and-osteoarthritis","/health/psoriatic-arthritis-vs-osteoarthritis","/health/rheumatoid-arthritis/ra-vs-oa","/health/osteoarthritis-prevention","/health/osteoarthritis/osteoarthritis-diet","/health/osteoarthritis/foods-to-avoid","/health/osteoarthritis-best-walking-and-running-shoes","/health/osteoarthritis/natural-home-remedies","/health/knee-arthritis-exercises-to-avoid","/health/osteoarthritis/hip-exercises-treatment","/health/total-knee-replacement-vitamins-supplements","/health/osteoarthritis/ashwagandha-osteoarthritis","/health/best-exercises-for-oa-symptoms","/health/osteoarthritis/supplements-to-consider","/health/best-yoga-poses-osteoarthritis","/health/how-to-ease-osteoarthritis-pain"],"moveImageGalleryBelowDeck":["/health/drugs/latuda-dosage","/health/drugs/spiriva-dosage","/health/drugs/rexulti-dosage","/health/drugs/humulin-n-dosage","/health/drugs/provigil-dosage","/health/drugs/cipro-dosage","/health/drugs/entyvio-dosage","/health/drugs/symbicort-dosage","/health/drugs/ajovy-dosage","/health/drugs/vraylar-dosage","/health/drugs/trintellix-dosage","/health/drugs/levemir-dosage","/health/drugs/xarelto-dosage","/health/drugs/ozempic-dosage","/health/drugs/pulmicort-dosage","/health/drugs/rybelsus-dosage","/health/drugs/humalog-dosage","/health/drugs/pristiq-dosage","/health/drugs/viagra-dosage","/health/drugs/cambia-dosage"],"showReferenceJumpLink":["/health/drugs/auvelity","/health/drugs/mounjaro","/health/drugs/nexlizet","/health/drugs/otezla","/health/drugs/rinvoq","/health/drugs/verzenio"],"showNonCostJumpLink":["/health/drugs/auvelity-interactions","/health/drugs/auvelity-cost","/health/drugs/auvelity-dosage","/health/drugs/mounjaro-side-effects","/health/drugs/mounjaro-dosage","/health/drugs/mounjaro-interactions","/health/drugs/mounjaro-cost","/health/drugs/nexlizet-cost","/health/drugs/nexlizet-side-effects","/health/drugs/nexlizet-dosage","/health/drugs/otezla-side-effects","/health/drugs/otezla-interactions","/health/drugs/otezla-dosage","/health/drugs/otezla-cost","/health/drugs/rinvoq-side-effects","/health/drugs/rinvoq-cost","/health/drugs/verzenio-side-effects","/health/drugs/verzenio-dosage","/health/drugs/verzenio-cost"]},"skipGDPR":true},"ab":{"enableDatadogRUM":false,"scrollIndicator":false,"prerollAdRule":false,"postrollAdRule":false,"activationReadNext":true,"adbDlbFix":false,"livedExperienceMVP":false,"expandedTableOfContents":false,"collapsedTableOfContents":false,"experimentalRPM":"variant","adbridgFlag":false,"jwPlayerFix":true,"dcsCopayBestOffer":"control","dcsNativeCoupon":"control","dcsCopayOnly":"variant","reducedFontSize":false,"moveImageGalleryBelowH2":false,"affiliateDisclaimer":false,"affiliateDisclaimer2":false,"adBlockerDetection":false,"contentClusterInfiniteScroll":false,"oneTrustCPRA":true,"pathingTest":true,"moveImageGalleryBelowDeck":"control","apscustomRemoval":false,"showClusterNavMenu":true,"showReferenceJumpLink":"control","showNonCostJumpLink":"control","traveler":"variant"},"abTestUrls":{"moveImageGalleryBelowH2":["/health/drugs/trulicity","/health/drugs/spiriva","/health/drugs/januvia","/health/drugs/olumiant","/health/drugs/trintellix","/health/drugs/zetia","/health/drugs/lybalvi","/health/drugs/sunosi","/health/drugs/nplate","/health/drugs/nexplanon","/health/drugs/leqvio","/health/drugs/taltz","/health/drugs/repatha","/health/drugs/venclexta","/health/drugs/nucala"],"prerollAdRule":["/nutrition/9-benefits-oats-oatmeal"],"postrollAdRule":["/health/fitness/weight-bench","/nutrition/best-punching-bag","/nutrition/protein-for-vegans-vegetarians","/nutrition/can-you-drink-rain-water"],"expandedTableOfContents":["/health/exercise-fitness/postnatal-exercises","/nutrition/red-clover","/health/baby/baby-banging-head","/health/bump-on-big-toe","/health/yellow-tongue","/health/onion-juice-for-hair","/nutrition/vegan-bodybuilding-diet","/health/skin-tear","/health/beauty-skin-care/is-soap-bad-for-skin","/health/perineum-pain","/health/sleeping-without-a-pillow","/health/scalp-yeast-infection","/health/how-to-shower","/health/pregnancy/what-causes-rashes-during-pregnancy-and-how-to-treat-them","/health/pregnancy/rib-pain","/health/heel-pain-in-the-morning","/health/baby/how-often-do-normal-couples-have-sex","/health/how-to-avoid-sleepiness-while-studying","/nutrition/banaba-leaf","/health/beauty-skin-care/hard-pimple","/health/womens-health/menstrual-cycle-and-the-moon","/health/pregnancy/babies-born-at-36-weeks","/health/adderall-effects-on-brain","/health/how-to-get-rid-of-pimple-scabs","/health/self-massage","/nutrition/soaking-almonds","/health/shaking-after-workout","/health/oat-allergy","/health/chalazion-surgery","/health/constipation-during-period","/health/cold-flu/cold-flu-secrets","/health/baby/baby-red-around-eyes","/health/pregnancy/signs-of-having-a-boy","/health/lines-under-eyes","/health/how-to-get-a-thicker-neck","/health/pregnancy/no-morning-sickness","/health/bone-health/the-4-main-types-of-posture","/health/positions-to-help-period-cramps","/health/how-to-regulate-periods","/health/eye-health/20-20-20-rule","/nutrition/greasy-food","/nutrition/copper-water-benefits","/health/itchy-forearms","/health/es/vitaminas-para-ojos-secos","/health/post-vacation-blues","/health/erectile-dysfunction/can-masturbation-cause-erectile-dysfunction","/health/meningitis-pictures-rash-symptoms","/health/postpartum-cramps","/health/acne-between-eyebrows","/health/throwing-up-blood-after-drinking","/health/gerd/gas","/health/bubble-bath-soaps","/health/herpes-esophagitis","/health/sunburned-scalp","/health/boron-testosterone","/health/birth-control/can-i-change-the-time-i-take-my-birth-control","/health/presyncope","/health/flu-symptoms","/health/urination-excessive-volume","/health/average-shoe-size-for-women","/health/beauty-skin-care/laser-treatment-for-acne-scars","/nutrition/black-eyed-peas-nutrition","/health/what-you-need-to-know-about-dental-crowns-made-from-zirconia","/nutrition/keratin-rich-foods","/health/exercise-fitness/what-to-do-after-working-out","/health/mango-fly","/nutrition/indian-gooseberry","/health/fitness-nutrition/poppy-seeds-drug-test","/health/flying-with-ear-infection","/health/womens-health/crying-during-period","/health/sweet-smelling-urine","/health/fell-down-the-stairs","/health/parenting/toddler-congestion-remedies","/health/treat-pimple-on-neck","/health/chondrodermatitis-nodularis-helicis","/health/how-to-prevent-split-ends","/health/body-modification/tattoo-blowout","/health/postpartum-diet","/health/diabetes/costus-igneus-side-effects","/health/pregnancy/pregnancy-mood-swings","/health/bruised-knuckles","/health/womens-health/why-does-my-breast-hurt-when-i-press-it","/health/baby/dropped-baby","/health/soft-wax-vs-hard-wax","/nutrition/what-to-eat-after-running","/health/exercise-fitness/never-skip-leg-day","/health/breastfeeding/how-to-combine-breastfeeding-and-pumping","/health/stomach-cramps-in-men","/health/sinus-rinse-dangers","/health/get-rid-of-scars-on-legs","/health/ciu/foods-to-eat-and-avoid","/health/beauty-skin-care/over-exfoliating","/health/dental-and-oral-health/tongue-sucking","/health/mens-health/bleeding-from-penis","/health/i-lost-weight-after-abortion","/health/calcium-deposits-on-skin","/health/bradypnea","/health/types-of-feet","/health/uneven-lips","/health/coagulation-tests","/health/erectile-dysfunction/surprising-facts","/health/pregnancy/third-trimester-nausea","/health/mental-health/nervous-laughter","/health/seated-row","/health/how-to-reduce-melanin","/health/headache-after-running","/health/anxiety/subconscious-anxiety","/health/why-smoking-reclaimed-cannabis-resin-isnt-a-good-idea","/nutrition/what-to-put-in-oatmeal","/health/baby/cleaning-babys-nose","/health/pregnancy/hidden-twin-ultrasound","/health/infected-mole","/health/pregnancy/ear-infection-while-pregnant","/health/endotough/period-symptoms-not-to-ignore","/health/cic/what-your-gut-is-trying-to-tell-you","/health/parenting/breastfeeding-lump","/health/skinned-knee","/health/scab-in-ear","/health/pineal-gland-dmt","/nutrition/foods-that-cause-blood-in-stool","/health/pregnancy/butt-pain","/health/withdrawal-bleeding","/health/white-pubic-hair","/health/pelvic-pain-in-men","/health/beauty-skin-care/how-to-get-shiny-hair","/health/cutis-marmorata","/health/mens-health/smelly-penis","/health/mens-health/pain-in-right-testicle-and-inner-thigh","/health/dental-and-oral-health/cut-on-gums","/health/scabies-on-the-penis","/health/hairy-butt-crack","/health/how-to-get-rid-of-smegma","/health/pimple-on-nipple","/health/canker-sore-on-tonsil","/health/fertility/how-to-inject-hcg","/health/beauty-skin-care/should-you-pop-a-pimple","/health/es/moco-en-las-heces","/health/food-grade-hydrogen-peroxide","/health/mental-health/tired-from-work","/health/skin-tag-on-tongue","/health/wound-dehiscence","/health/dental-and-oral-health/black-triangles-teeth","/health/hairy-nipples","/health/fitness/pull-ups-everyday","/health/ear-blowout","/health/pregnancy/soda-during-pregnancy","/health/pregnancy/toothpaste-pregnancy-test","/health/pregnancy/pcos-and-pregnancy-test","/health/beauty-skin-care/double-crown-hair","/health/hiv-aids/cd4-viral-count","/health/do-cortisone-shots-work-for-acne","/health/itchy-throat-covid","/nutrition/sole-water","/nutrition/apetamin","/health/parenting/cracked-nipples","/health/tranexamic-acid-side-effects","/health/mental-health/eating-dirt","/health/elisa","/health/es/pan-para-diabeticos","/health/am-i-lesbian","/health/relationships/breadcrumbing","/nutrition/maca-root-for-curves","/health/aloe-vera-for-acne","/nutrition/galangal-root","/health/fear-of-intimacy","/health/whitehead","/health/childrens-health/baby-acne","/health/substance-use/smoking-mdma","/nutrition/foods/wheat","/health/pregnancy/how-to-get-pregnant-with-pcos","/health/es/diabetes-tipo-2-y-piel","/health/saggy-balls","/health/fitness/deadlift-benefits","/health/pregnancy/what-medicines-are-safe-during-pregnancy","/health/birth-control/missed-one-birth-control-pill-can-i-get-pregnant","/health/infection/cephalexin-alcohol","/health/testicle-lump","/health/birth-control/i-accidentally-took-2-birth-control-pills-in-one-day","/health/es/palpitaciones-en-el-corazon-por-la-noche","/health/pimple-in-throat","/health/penis-fish","/health/mens-health/hairy-penis","/health/birth-control/missed-one-pill-and-had-unprotected","/health/rust-on-skin","/health/mens-health/penis-irritation","/health/erectile-dysfunction/horny-goat-weed","/health/freebasing","/health/masturbation-effects-on-kidney","/health/transgender/tucking","/health/high-blood-pressure-hypertension/during-pregnancy","/health/hydrocortisone-for-acne","/health/pregnancy-after-vasectomy","/health/pregnancy/how-to-prepare-your-body","/health/es/escamacion-de-las-yemas-de-los-dedos","/health/breastfeeding/nipple-biting","/health/how-to-make-your-nose-smaller","/health/exercise-for-nose","/health/pregnancy/bloody-stool-pregnancy","/health-news/how-you-can-die-from-caffeine","/health/womens-health/ovarian-cyst-treatment-at-home","/health/skin-allergy-home-remedy","/health/pregnancy/evaporation-line-pregnancy-test","/health/biliary-colic","/health/drinking-bleach","/health/breastfeeding/breastfeeding-and-antibiotics","/health/anxiety-sore-throat","/health/pms-mood-swings","/health/hamstring-curls","/health/high-pain-tolerance","/health/exercise-to-gain-weight","/nutrition/oatmeal-alternatives","/health/ear-stretching","/nutrition/working-out-while-sick","/health/beauty-skin-care/vaseline-on-lips","/health/exercise-fitness/cooldown-exercises","/health/pregnancy/2-vessel-cord","/health/acne-keloidalis-nuchae","/nutrition/cherimoya","/health/baby/how-to-clean-baby-tongue","/health/baby/baby-acne-breast-milk","/health/24-hour-urine-protein","/health/eye-health/mucus-fishing-syndrome","/health/mens-health/thrush-in-men","/health/jojoba-oil-for-hair","/health/armpit-pimple","/health/jumping-rope-to-lose-weight","/health/es/sangre-en-las-heces","/health/why-do-i-talk-to-myself","/health/homeopathy-for-anxiety","/health/fitness/how-to-build-strength-guide","/health/pimple-that-won-t-go-away","/health/beauty-skin-care/no-poo","/health/scapular-winging","/health/relationships/one-sided-relationship","/health/pregnancy/ring-gender-test","/health/baby/baby-wont-nap","/health/tooth-sensitive-to-hot-and-cold","/health/dental-and-oral-health/transparent-teeth","/health/fitness/squats-for-glutes","/health/home-remedies-for-gonorrhea","/health/ingrown-toenail-infection","/health/womens-health/do-your-breasts-hurt-when-they-grow","/health/childrens-health/angry-toddler","/health/pregnancy/hot-pregnant","/health/moldy-weed","/nutrition/ayurvedic-herbs","/health/pregnancy/pregnant-and-horny","/health/pregnancy/how-long-does-hcg-stay-in-your-system","/health/cold-sore-triggers","/health/how-to-decrease-libido","/nutrition/loss-of-appetite-pregnancy","/health/antibiotics/antibiotics-and-weed","/health/asymmetrical-face","/health/leg-press-alternative","/health/tonsillectomy-scabs","/health/sacralization","/health/benefits-of-playing-chess","/health/betel-nut-dangers","/nutrition/ginger-for-sex","/health/dark-line-on-stomach-not-pregnant","/health/pregnancy/ovary-pain-early-pregnancy","/health/sore-throat-after-drinking","/health/beauty-skin-care/pockmarks","/health/how-to-stretch-foreskin","/health/beauty-skin-care/almond-oil-for-face","/health/chemically-castrating","/health/how-to-get-rid-of-redness-from-pimples","/health/womens-health/light-headed-during-period","/health/blood-group-compatibility-for-marriage","/health/oral-rehydration-solution","/health/period-flu","/health/exercise-fitness/average-10k-time","/health/recurring-thrush","/health/baby/how-to-cut-baby-hair","/health/male-discharge-normal","/health/how-to-be-charismatic","/health/pregnancy/loose-skin-postpartum","/health/pregnancy/skull-theory","/health/arrhythmia/drugs","/health/blue-toenails","/health/melanin-in-hair","/health/feels-hot-to-touch","/health/baby/eruption-cyst-baby","/health/beauty-skin-care/deep-blackheads","/health/birth-control/cramps-on-birth-control","/health/hiv-aids/symptoms-men","/health/angiokeratoma","/health/left-arm-pain-anxiety","/health/cauterizing-a-wound","/health/abdominal-pain-and-breast-tenderness","/health/medications-workouts-do-not-mix","/health/oily-nose","/health/pilonidal-cyst-surgery","/nutrition/carom-seeds","/health/pregnancy/how-to-increase-amniotic-fluid","/health/womens-health/period-changes-20s-30s-40s-50s","/health/fitness/drinking-after-workout","/health/big-testicles","/health/signs-of-pregnancy-while-on-birth-control","/health/chest-pain-and-diarrhea","/health/can-you-get-high-from-smelling-weed","/health/es/como-dormir-con-tos","/health/mens-health/testicular-retraction","/health/exercise-fitness/running-on-an-empty-stomach","/health/delayed-growth-symptom","/health/dizzy-when-blowing-nose-ears-popping","/health/crown-of-head","/health/relactation","/health/es/funciona-la-biotina-para-el-crecimiento-del-cabello","/health-news/does-jawzrsize-really-work","/health/signs-that-someone-is-using-crystal-meth","/health/saliva-blood","/health/rashes-from-pads","/health-news/can-ice-baths-help-you-burn-body-fat-new-research-says-yes","/health/chest-and-neck-pain","/health/the-causes-of-overlapping-toes-and-treatment-options","/health/headache-after-exercise","/health/growing-pains-in-adults","/health/es/tipos-de-caca","/health/mens-health/one-testicle-bigger-than-the-other","/health/hypertrophic-scar-piercing","/health/exercise-fitness/16-dumbbell-exercises-for-abs","/health/gingival-hyperplasia","/health/beauty-skincare/thin-skin-under-eyes","/nutrition/sour-foods","/health/birth-control/how-to-avoid-pregnancy","/health/fitness-exercise/push-ups-for-biceps","/health/double-penetration","/health/laser-carbon-peel","/health/toasted-skin-syndrome","/health/mens-health/painful-ejaculation","/health/pregnancy/mucus-plug-early-pregnancy","/health/baby/dehydration-in-babies","/health/tinea-manuum","/health/birth-control/late-period-after-stopping-birth-control","/health/ulcers-in-babys-mouth","/nutrition/tomato-juice","/health/womens-health/endometriosis-leg-pain","/health/eye-health/greyish-spot-on-white-of-eye","/health/birth-control/weight-loss-after-iud-removal","/health/penis-pain","/health/parenting/breastfed-poop","/health/colloidal-silver","/health/baby/white-curds-in-baby-poop","/health/es/monocitos-altos","/health/pregnancy/implantation-calculator","/health/pimple-pus","/health/what-is-sandalwood","/health/addiction/sex","/health/daytime-sleepiness/tips-for-work","/health/tongue-piercing-healing-stages","/health/adhd/supplements","/health/blood-culture","/health/high-libido","/health/itchy-acne","/health/what-are-blemishes","/nutrition/a1-vs-a2-milk","/nutrition/foods/beef","/health/fitness-exercise/karate-vs-taekwondo","/health/baby/baby-rubbing-eyes","/health/fitness-exercises/better-sex-workout","/health/how-to-get-gum-out-of-hair","/health/womens-health/effective-yeast-infection-remedies","/nutrition/weight-loss-diet-plan-for-men","/health/womens-health/how-many-days-between-periods","/health/pregnancy/implantation-cramping","/health/substance-use/coke-bloat","/health/beauty-skin-care/shampoo-or-conditioner-first","/nutrition/bananas-with-milk","/health/shortness-of-breath-early-pregnancy","/health/retinol-for-acne","/health/pregnancy/pregnancy-symptoms-week-10","/health/types-of-relationships","/health/birth-control/starting-birth-control-mid-cycle","/nutrition/what-is-arrowroot","/nutrition/yam-benefits","/nutrition/spirulina-side-effects","/health/hydrocele","/health/mens-health/average-testicle-size","/health/beauty-skin-care/honey-and-lemon-for-face","/health/can-you-take-a-bath-on-period","/health/pregnancy/third-trimester-pain-insomnia","/nutrition/tahini-benefits","/health/pregnancy/crying-during-pregnancy","/health/substance-use/lsd-vs-shrooms","/nutrition/turmeric-benefits-weight-loss","/nutrition/arnica-homeopathic","/health/stiff-back","/health/low-cheekbones-vs-high-cheekbones","/health/female-sexual-arousal-disorder","/health/mens-health/left-testicle-pain","/health/how-long-do-hickeys-last","/health/unconsciousness-first-aid","/health/mens-health/irritable-male-syndrome","/health/sexual-coercion","/health/does-masturbation-increase-blood-pressure","/health/sloped-shoulders","/health/pus-in-ear","/health/heimlich-maneuver","/health/birth-control/how-long-is-too-long-to-be-on-birth-control"],"collapsedTableOfContents":[],"livedExperienceMVP":["/health/regrow-hair-naturally","/health/cold-flu/sore-throat-natural-remedies","/nutrition/13-acne-remedies","/health/natural-ways-to-reduce-anxiety","/nutrition/zinc-supplements","/health/losing-a-parent","/health/does-rogaine-work","/health/food-nutrition/best-vitamins-to-take-daily","/nutrition/do-multivitamins-work","/nutrition/pre-workout-supplements","/nutrition/best-cooking-oils","/health/sunscreen-for-oily-skin","/nutrition/best-gluten-free-bread","/health/beauty-skin-care/best-sunscreens-for-dark-skin","/health/best-natural-shampoo","/health/thrive-market-review","/nutrition/best-testosterone-booster-supplements","/health/pregnancy/best-breast-pump","/nutrition/metabolic-renewal-reviews","/nutrition/best-weight-gain-supplements","/nutrition/best-snacks-for-diabetes","/nutrition/best-foods-for-constipation","/health/high-bilirubin","/nutrition/foods-to-avoid-with-kidney-disease-and-diabetes","/health/mental-health/how-to-cope-with-anxiety","/health/natural-ways-to-reduce-migraines","/health/diabetes","/health/high-cortisol-symptoms","/health/high-blood-pressure-home-remedies","/health/anxiety/anxiety-nausea","/health/osteoarthritis/arthritis-natural-relief","/health/hormonal-imbalance","/health/how-to-stop-ruminating","/health/cold-flu/how-to-get-rid-of-phlegm","/nutrition/6-proven-health-benefits-of-apple-cider-vinegar"],"reducedFontSize":["/health/womens-health/vaginal-boils","/health/how-to-get-rid-of-sinus-infection","/health/womens-health/safe-period","/health/shingles-contagious","/nutrition/ginseng-benefits","/health/es/erupcion-cutanea","/health/food-nutrition/what-to-eat-after-food-poisoning","/health/how-to-stop-being-high","/health/eft-tapping","/nutrition/dragon-fruit","/nutrition/6-benefits-of-oil-pulling","/nutrition/10-signs-and-symptoms-of-ketosis","/health-news/the-real-housewives-of-new-jersey-star-dolores-catania-lost-20-pounds-taking-ozempic-mounjaro","/health/crohns-disease/would-get","/health/fitness/back-strengthening-muscles-posture","/health/home-remedies-for-warts","/nutrition/avocado-nutrition","/health/pain-on-top-of-the-foot","/health/how-long-does-acid-last","/health/womens-health/one-day-period","/health/es/remedios-caseros-para-los-calculos-renales","/health/mens-health/pe-home-remedies","/health/pain-in-back-of-head","/health/sore-eye-remedies","/health/nofap-benefits","/health/es/alivio-del-dolor-de-la-vesicula-biliar","/health/grounding","/health/exercise-fitness/lower-ab-workouts","/nutrition/low-carb-diet-meal-plan-and-menu","/health/food-stuck-in-throat","/nutrition/eat-after-workout","/nutrition/best-fish-oil-supplement","/health/pebble-poop","/nutrition/dandelion-benefits","/health/dizziness-and-fatigue","/health/gerd/diet-nutrition","/nutrition/foods-loaded-with-potassium","/health/how-to-stop-loving-someone","/nutrition/vitamin-c-foods","/health/dental-and-oral-health/sore-tongue","/health/inner-knee-pain","/health/mosquito-bite-blister","/health/healthy-sex/what-are-butt-plugs-used-for","/nutrition/8-benefits-of-kombucha-tea","/health/how-to-tan-faster","/health/mosquito-blood-type","/health/baby/baby-hit-head","/nutrition/get-rid-of-pimples-fast","/health/best-scar-cream","/health/cold-flu/home-remedies-for-dry-cough","/nutrition/lean-protein-foods","/health/baby/why-cant-babies-have-water","/health/how-to-stop-sweating-face","/health/home-remedies-for-itchy-scalp","/nutrition/best-vitamin-brands","/nutrition/ways-to-tell-if-ground-beef-is-bad","/health/how-to-stop-a-panic-attack","/nutrition/9-foods-to-help-you-sleep","/health/es/como-quitar-la-congestion-nasal","/nutrition/10-benefits-of-creatine","/health/sexually-transmitted-diseases/home-remedies-for-herpes","/nutrition/aloe-vera-juice-benefits","/health/snot-color","/nutrition/carnivore-diet","/health/best-protein-powder","/nutrition/10-baking-powder-substitutes","/nutrition/saffron","/health/shoulder-pain-exercises","/health/toxic-relationship","/health/es/superior-izquierda-dolor-abdominal-bajo-costillas","/health/es/como-quitar-las-ganas-de-vomitar","/health/es/remedios-caseros-para-el-dolor-de-estomago","/nutrition/foods-high-in-soluble-fiber","/health/home-remedies-for-tonsilitis","/health/skin-disorders/red-bumps-on-legs","/nutrition/zero-calorie-foods","/health/iron-infusion","/health/beauty-skin-care/niacinamide","/health/skin/tretinoin","/nutrition/apple-cider-vinegar-side-effects","/nutrition/healthiest-beans-legumes","/health/home-remedies-for-abscess-tooth","/health/digestive-health/diarrhea-after-eating","/health/digestive-health/most-effective-diarrhea-remedies","/nutrition/6-ways-to-do-intermittent-fasting","/health/poop-stuck-halfway-out","/nutrition/benefits-of-walnuts","/health/gut-health","/nutrition/12-proven-benefits-of-pomegranate","/nutrition/best-protein-bars","/health/es/dolor-en-la-espalda-el-lado-derecho-inferior","/health/vulva-vagina-products","/nutrition/foods-with-estrogen","/health/healthy-sex/lube-shopping-guide-types","/nutrition/top-10-evidence-based-health-benefits-of-coconut-oil","/health/gallbladder-pain-relief","/health/adhd/adult-adhd","/nutrition/vitamin-k2","/nutrition/sleep-aids","/health/healthy-home-guide/how-to-get-rid-of-fleas"],"affiliateDisclaimer":["/health/broad-spectrum-cbd","/health/womens-health/garden-of-life-reviews","/health/social-cbd","/health/spruce-cbd-review","/health/air-purifier-for-smoke","/health/massage-chair-pads","/health/ecg-monitor","/health/best-blood-pressure-monitor-watches","/nutrition/best-exercise-bike-for-home","/nutrition/fitness-trackers-for-women","/nutrition/peloton-bike-alternatives","/nutrition/best-elliptical","/health/best-fit-test","health/acupressure-mat","health/best-thermometer","/health/dental-and-oral-health/best-teeth-whitening","/health/costco-hearing-aids","/health/lively-hearing-aids","/nutrition/best-multivitamin-for-men-over-50","/health/regrow-hair-naturally","/health/erectile-dysfunction/medication-list","/health/erectile-dysfunction/viagra-alternative","/health/talkspace-reviews","/nutrition/meal-delivery-for-seniors","/nutrition/trifecta-meals","/nutrition/best-protein-bars","/health/parenting/best-toddler-pillows","/health/parenting/toys-for-kids-with-autism","/health/beauty-skin-care/best-vitamin-c-serum","/health/pregnancy/best-stretch-mark-creams-for-pregnancy","/health/beauty-skin-care/best-eye-cream-for-dark-circles","/health/healthy-sleep/best-full-size-mattress","/health/healthy-sleep/best-eucalyptus-sheets","/health/healthy-sleep/split-king-mattress","/health/best-earplugs-for-sleeping","/health/glasses-online","/health/blue-light-glasses-for-kids","/nutrition/care-of-vitamins","/nutrition/olly-vitamins-review","/health/pure-vitamins"],"affiliateDisclaimer2":["/cbd/top-cbd-brands","/cbd/best-cbd-cream-for-pain","/cbd/best-cbd-for-sleep","/cbd/best-cbd-gummies","/cbd/best-cbd-gummies-for-anxiety","/cbd/the-best-cbd-gummies-for-pain","/cbd/best-cbd-oil","/cbd/strongest-cbd-gummies","/nutrition/best-creatine","/health/online-cialis","/health/mens-health/generic-viagra","/health/hims-ed-review","/health/hims-vs-roman","/health/mens-health/viagra-online","/health/therapy-for-every-budget","/health/mental-health/betterhelp-review","/health/mental-health/online-therapy-that-takes-insurance","/nutrition/best-meal-delivery-service","/nutrition/best-prepared-meal-delivery-service","/nutrition/buy-ozempic-online","/nutrition/how-to-get-wegovy","/nutrition/ro-review","/nutrition/best-multivitamins-for-men","/nutrition/multivitamins-womens-health","/health/pregnancy/best-prenatal-vitamins","/nutrition/best-probiotic-supplement","/health/food-nutrition/best-probiotics-women","/nutrition/buy-zepbound-online","/cbd/cbd-gummies-for-sleep","/health/cornbread-hemp","/health/strongest-cbd-oil","/health/at-home-std-test","/health/mens-health/bluechew-vs-hims","/health/hair-growth-products","/health/roman-ed-review","/health/our-top-10-online-therapy-picks","/health/mental-health/online-therapy-for-teens","/nutrition/factor-75","/nutrition/weight-loss-meal-delivery","/health/drugs/wegovy-prescription-online","/health/best-cbd-oil-for-anxiety","/nutrition/best-fish-oil-supplement","/nutrition/best-vitamin-brands","/health/birth-control/birth-control-online","/health/cbd-oil-for-joint-pain","/health/mens-health/male-enhancement-pills","/health/mental-health/online-psychiatrist","/health/vitamin-deficiency-test","/cbd/cbd-for-stress","/health/uti-home-remedies","/nutrition/best-mass-gainer","/nutrition/best-heart-rate-monitoring-watch","/nutrition/best-vegan-protein-powder-review","/nutrition/buy-mounjaro-online","/health/hair-loss-treatments-for-men","/nutrition/best-protein-powders-for-weight-loss","/nutrition/best-magnesium-supplement","/nutrition/vitamins-for-kids","/health/healthy-sex/free-sti-testing","/health/ed-pills-online","/health/healthy-sex/how-to-get-harder-erections","/health/drugs/ozempic-alternatives","/cbd/best-cbd-capsule","/health/full-spectrum-cbd","/health/full-spectrum-cbd-tincture","/health/thc-free-cbd-oil","/nutrition/diabetic-meal-delivery","/health/hormone-test-at-home","/health/thyroid-at-home-test","/health/mental-health/online-sex-therapy","/health/testosterone-test-kits","/health/viagra-price","/health/mental-health/online-therapist-for-free","/nutrition/cheapest-meal-delivery-service","/nutrition/gluten-free-meal-delivery","/nutrition/healthy-meal-delivery","/nutrition/keto-meal-delivery","/nutrition/best-mediterranean-diet-meal-delivery","/nutrition/organic-meal-delivery","/nutrition/plant-based-meal-delivery","/nutrition/athletic-greens-review","/nutrition/personalized-vitamins","/health/cortisol-tests","/health/bluechew-vs-roman","/nutrition/best-weight-loss-apps","/health/food-sensitivity-test","/nutrition/how-to-get-mounjaro","/nutrition/how-to-get-zepbound","/nutrition/best-multivitamin-for-women-over-50","/nutrition/creatine-for-women","/health/menopause/menopause-home-test","/health/mens-health/keeps-vs-hims","/health/nutrafol-reviews","/cbd/best-cbd-for-arthritis-pain","/health/top-10-cbd-lotions-creams-and-topicals","/cbd/cheap-cbd-oil","/health/everlywell-review","/health/erectile-dysfunction/otc","/nutrition/best-weight-loss-programs","/nutrition/weight-loss-medication","/nutrition/best-iron-supplement","/nutrition/best-vitamin-d-supplements","/health/cbd-for-energy","/health/best-protein-powder","/nutrition/best-greens-powder","/health/erectile-dysfunction/cialis-levitra-viagra","/health/digestive-health/whats-the-best-fiber-supplement","/health/cbdfx","/health/mental-health/therapy-for-kids","/nutrition/best-body-fat-scale","/health/pregnancy/best-breast-pump","/nutrition/best-turmeric-supplements","/nutrition/best-vitamin-b-supplement","/nutrition/best-vitamins-hair-growth","/health/womens-health/hers-review","/health/healthy-sleep/cloud-mattress","/health/fitness-exercise/best-dumbbells","/health/parenting/best-postpartum-hair-products","/health/pregnancy/best-stretch-mark-creams-for-pregnancy","/nutrition/seed-probiotics-review","/health/std-treatment-online","/nutrition/best-hair-skin-and-nails-vitamins","/health/birth-control/where-to-get-plan-b","/health/optum-viagra","/nutrition/low-carb-protein-powders","/health/best-knee-compression-sleeves","/health/best-stethoscopes","/nutrition/best-protein-bars","/health/erectile-dysfunction/medication-list","/health/generic-cialis","/health/drugs/mounjaro-for-weight-loss","/health/4-supplements-as-powerful-as-drugs","/health/decolletage","/health/grounding","/health/beauty-skin-care/nose-pores","/health/how-to-use-kegel-balls","/health/baby/baby-rolling-over-in-sleep","/health/butt-sweat","/health/thinning-hair","/health/boost-your-libido-10-natural-tips","/health/shampoo-seborrheic-dermatitis","/health/fitness-exercise/pool-exercises","/health/broken-tailbone","/health/anxiety/social-anxiety-treatment","/health/beauty-skin-care/how-to-get-rid-of-large-pores","/health/pregnancy/padsicles","/health/low-testosterone/warning-signs","/health/drugs/wegovy-cost","/health/anal-douche","/health/how-to-find-out-your-blood-type","/health/low-porosity-hair","/health/what-is-a-cock-ring-used-for","/health/mthfr-gene","/health/healthy-sex/anal-sti-test","/health/parenting/toddler-yeast-infection","/health/what-is-a-metabolism-test-and-can-you-use-it-for-weight-loss-and-fitness","/health/hip-pain-at-night","/health/allergic-to-bandaids","/health/beauty-skin-care/how-to-use-hyaluronic-acid","/health/cbd-for-insomnia","/health/erectile-dysfunction","/health/erectile-dysfunction/ed-pills","/nutrition/do-collagen-supplements-work","/nutrition/collagen","/health/hair-loss-prevention","/health/cbd-oil-for-pain","/health/erection-problems","/health/how-long-does-cbd-stay-in-your-system","/health/erectile-dysfunction/can-masturbation-cause-erectile-dysfunction","/health/erectile-dysfunction/young-men","/health/erectile-dysfunction/surprising-facts","/health/cbd-for-anxiety","/nutrition/how-much-collagen-per-day","/health/womens-health/yeast-infection-home-remedy","/nutrition/collagen-benefits","/health/nerve-pain-medication-over-the-counter","/health/sore-after-massage","/health/how-to-delay-period-naturally","/health/swollen-eyes-from-crying","/health/depression/morning-depression"],"contentClusterInfiniteScroll":["/health/osteoarthritis-symptoms","/health/osteoarthritis/crepitus","/health/cracking-shoulder","/health/osteoarthritis/heberdens-nodes","/health/early-symptoms-osteoarthritis","/health/osteoarthritis/osteoarthritis-flare-up","/health/osteoarthritis-pictures","/health/osteoarthritis/osteoarthritis-hip-x-ray","/health/osteoarthritis/what-does-arthritis-look-like-on-an-mri","/health/osteoarthritis/oa-of-the-knee-xray","/health/osteoarthritis/tricompartmental-osteoarthritis","/health/osteoarthritis/big-toe","/health/subchondral-sclerosis","/health/osteoarthritis/what-is-erosive-osteoarthritis","/health/glenohumeral-osteoarthritis","/health/osteoarthritis/osteoarthritis-hand","/health/sacroiliitis","/health/osteoarthritis-spine","/health/bilateral-knee-osteoarthritis","/health/rapid-destructive-hip-osteoarthritis","/health/osteoarthritis/medial-compartmental-osteoarthritis","/health/posttraumatic-osteoarthritis","/health/osteoarthritis/osteoarthritis-shoulder","/health/osteoarthritis/hypertrophic-osteoarthropathy","/health/osteoarthritis/knee/osteoarthritis-of-the-knee","/health/osteoarthritis-treatment","/health/osteoarthritis/arthritis-hand-exercises","/health/osteoarthritis/platelet-rich-plasma-knee","/health/osteoarthritis/hip-treatments","/health/chiropractor-for-hip-pain","/health/osteoarthritis/knee-injections-for-osteoarthritis","/health/osteoarthritis/over-counter-relief","/health/osteoarthritis/medications-list","/health/types-of-osteoarthritis-braces","/health/osteoarthritis/synvisc-vs-hyalgan","/health/osteoarthritis/total-hip-replacement","/health/regenokine","/health/osteoarthritis/treatment-options-for-delaying-knee-surgery","/health/osteoarthritis/qa-treatments","/health/total-knee-replacement-surgery/rehabilitation-timeline","/health/total-knee-replacement-surgery/managing-postoperative-pain","/health/knee-replacement-infection","/health/knee-replacement-surgery","/health/total-knee-replacement-surgery/surgical-options","/health/total-knee-replacement-surgery-step-by-step","/health/total-knee-replacement-surgery/medications","/health/total-knee-replacement-surgery/sports-activities-after","/health/total-knee-replacement-surgery/insomnia-depression","/health/total-knee-replacement-surgery/risks-complications","/health/total-knee-replacement-surgery/understanding-costs","/health/total-knee-replacement-surgery/outcomes-statistics-success-rate","/health/total-knee-replacement-surgery/common-questions","/health/preparing-your-home-knee-replacement-recovery","/health/knee-replacement-artificial-joints-versus-natural","/health/total-knee-replacement-surgery/expectations","/health/total-knee-replacement-surgery/implant-manufacturers","/health/total-knee-replacement-surgery-daily-life","/health/total-knee-replacement-surgery","/health/after-total-knee-replacement-surgery","/health/total-knee-replacement-surgery/when","/health/total-knee-replacement-surgery/orthopedic-evaluation","/health/total-knee-replacement-surgery/follow-up-appointments","/health/common-causes-osteoarthritis","/health/osteoarthritis-stages-of-oa-of-the-knee","/health/osteoarthritis/advanced-osteoarthritis","/health/osteoarthritis/complications-and-dangers","/health/osteoarthritis/knee-pain/link-between-weight-loss-and-knee-pain","/health/covid-and-osteoarthritis","/health/psoriatic-arthritis-vs-osteoarthritis","/health/rheumatoid-arthritis/ra-vs-oa","/health/osteoarthritis-prevention","/health/osteoarthritis/osteoarthritis-diet","/health/osteoarthritis/foods-to-avoid","/health/osteoarthritis-best-walking-and-running-shoes","/health/osteoarthritis/natural-home-remedies","/health/knee-arthritis-exercises-to-avoid","/health/osteoarthritis/hip-exercises-treatment","/health/total-knee-replacement-vitamins-supplements","/health/osteoarthritis/ashwagandha-osteoarthritis","/health/best-exercises-for-oa-symptoms","/health/osteoarthritis/supplements-to-consider","/health/best-yoga-poses-osteoarthritis","/health/how-to-ease-osteoarthritis-pain"],"moveImageGalleryBelowDeck":["/health/drugs/latuda-dosage","/health/drugs/spiriva-dosage","/health/drugs/rexulti-dosage","/health/drugs/humulin-n-dosage","/health/drugs/provigil-dosage","/health/drugs/cipro-dosage","/health/drugs/entyvio-dosage","/health/drugs/symbicort-dosage","/health/drugs/ajovy-dosage","/health/drugs/vraylar-dosage","/health/drugs/trintellix-dosage","/health/drugs/levemir-dosage","/health/drugs/xarelto-dosage","/health/drugs/ozempic-dosage","/health/drugs/pulmicort-dosage","/health/drugs/rybelsus-dosage","/health/drugs/humalog-dosage","/health/drugs/pristiq-dosage","/health/drugs/viagra-dosage","/health/drugs/cambia-dosage"],"showReferenceJumpLink":["/health/drugs/auvelity","/health/drugs/mounjaro","/health/drugs/nexlizet","/health/drugs/otezla","/health/drugs/rinvoq","/health/drugs/verzenio"],"showNonCostJumpLink":["/health/drugs/auvelity-interactions","/health/drugs/auvelity-cost","/health/drugs/auvelity-dosage","/health/drugs/mounjaro-side-effects","/health/drugs/mounjaro-dosage","/health/drugs/mounjaro-interactions","/health/drugs/mounjaro-cost","/health/drugs/nexlizet-cost","/health/drugs/nexlizet-side-effects","/health/drugs/nexlizet-dosage","/health/drugs/otezla-side-effects","/health/drugs/otezla-interactions","/health/drugs/otezla-dosage","/health/drugs/otezla-cost","/health/drugs/rinvoq-side-effects","/health/drugs/rinvoq-cost","/health/drugs/verzenio-side-effects","/health/drugs/verzenio-dosage","/health/drugs/verzenio-cost"]},"ga":{"k1":"marijuanause","k2":"substanceuse","kmeta":"eczema-predictive-aq,nsclc-predictive-aq,obesity-predictive-aq,bipolar-predictive-aq-1,bipolar-predictive-aq,vraylar24bp","contentType":"Tabbed Article","author":"Crystal Raypole","articleType":"regular","sponsoredProgramId":"","articleId":"wp-96687","mainContentCategoryTags":"","publishedDate":"2019-05-17","updatedDate":"2024-04-02","medReviewer":"Alan Carter, Pharm.D.","category":"Uncategorized","subcategory":"","trackingTerms":"","ek1":"2451d4dc77dcf393b196757b","ekmeta":"2c53dcd070c8bf8da286627765df54e15bfb829f,2743c5d97e84e28fb5876f7d72c24bf213b792,2652c3c674ddebd0a091637a6fc849fe48b3ce8f25,2b59d6da71c8e0d0a091637a6fc849fe48b3ce8f251715,2b59d6da71c8e0d0a091637a6fc849fe48b3ce8f25,3f42c7cc71c8e0cfe48176,","contentForm":"Non-Head Term","type":"healthfeature"},"adb":false,"d":[],"i":{"enabled":true},"cIds":["49883d0f-b8f7-458f-8a0d-a44fc3987eb8"],"mpd":{"loaded":[{"_driverPath":"/health/endocannabinoid-system","_contentIndex":"page","driverId":"c54448fb-575c-413d-993f-5cf346330a9f","siteId":"3bd23390-7108-11ea-8600-afc672063050","site":"hl","status":"on","deleted":false,"overridePredictiveRPM":false,"created":"2022-12-19T19:59:53.000Z","updated":"2024-11-05T21:03:43.000Z","createdBy":"liallison@redventures.com","updatedBy":"mrobinson@rvohealth.com","isTest":false,"overridePredictiveRPMType":"none","rewardType":"","customModel":false,"holdout":"","sdapiTestName":"","modelType":"","imageMobile":"https://media.post.rvohealth.io/2kLEJX4A3LDe7GGDNr31WST2A26/2024/09/26/2mc75hgmcKGdy2Btow91zCpyUlu.jpeg","color":"#02838d","driverTypeId":"1ed6a315-4241-4254-92ae-17d0570ee038","sailthruAccount":"hl","titleOverride":"The health and wellness newsletter you’ve been looking for ","newsletterSource":"Wellness Wire","id":"3c10d216-ff83-4e7e-8e69-dd0be853dcba","trackingNumber":39699,"adTagIds":["5bfa54a0-cb61-11ea-841d-230b5918b98d"],"articlePlacement":"headerNewsletter","image":"https://healthline-activation-prod.healthline.com/driver-images/Wellness%20Wire%20Relaunch%20-%20Visual%20Driver-732x549-Thumbnail%20(1).jpg","titleOverrideMobile":"The health and wellness newsletter you’ve been looking for ","secondaryNewsletters":[],"descriptionModal":"Interested in exclusive interviews, must-have products, and staying updated with trending news? Wellness Wire has it all, and you don’t want to miss out.","driverType":"headerNewsletter","verticalId":"5474f994-0335-422b-aab5-b87a0410aec6","verticalName":"Wellness Wire","lists":["Wellness Wire"],"name":"lifecycle_header_hl_wewi_newsletter","imageDesktop":"https://healthline-activation-prod.healthline.com/driver-images/Wellness%20Wire%20Relaunch%20-%20Visual%20Driver-700x1076-Desktop%20Driver.jpg","descriptionModalMobile":"Interested in exclusive interviews, must-have products, and staying updated with trending news? Wellness Wire has it all, and you don’t want to miss out.","driverPlacementId":"d5b8e667-55c1-4a6d-b05d-728a1733109b","campaignName":"lifecycle_header_hl_wewi_newsletter_39699","productId":"lifecycle_header_hl_wewi_newsletter_39699","_uuid":"mdf023cc0-853f-415a-9fa6-5455aaf12c12mpd_headerNewsletter_c54448fb-575c-413d-993f-5cf346330a9f","cpm":9.210263698372723e+306}],"placed":{},"placements":{},"state":{}},"e":[],"st":{"ddQ":[]},"jwp":{},"m":{"build":"12037910632","version":"60f1453e4b7e2d9efee0502a483780c4fbbd643c","environment":"prod"}}; hlIs=!1; var googletag=googletag||{cmd:[]}; __hlConfig={"travelerScript":"https://traveler.content.now.optum.com/traveler.umd.js","urlPrefix":"www.","absUrl":true,"tagular":{"apiVersion":"v2/t","writeKey":"wk_1Tqf7EYzOKyxm4Gvq042rU0Uky0","sourceKey":"src_1Tqf7BF96WTbG5QbUndHWIgKoFo","domainWhitelist":["www.healthline.com","act.healthline.com","frontend-stage.healthline.com","act-stage.healthline.com","activation.healthline.com","activation-stage.healthline.com"],"cookieDomain":"healthline.com","multiparty":true,"reinforce":"https://www.healthline.com/navi","experimentalFeatures":{"flocEnabled":true},"eventSampling":{"eligibleEvents":["DomCompleted","PageScrolled"],"fireRate":25}},"preamp":{"siteId":"2ahYQ7GmZHnMGlBjvg6cFP"},"metricServer":"https://pavlov-prod.healthline.com/","googleRecaptchaSiteKey":"6LcXCYopAAAAAJd3lQzyqu4Q0atIlXh0DRpaJAqn","marketplaceAPI":"https://prepop.healthline.com/export/form-data/","activationHost":"https://activation.healthline.com","datadogRUM":{"applicationId":"512348e0-2b09-41ef-ba89-972c7e598ad8","clientToken":"pub4a8701b4f057fee58e8d2a3dd85184f1"},"gtmServer":"https://gtm-server.healthline.com","gtmConfigValue":"GTM-MB6365D","aimDmdApiKey":"14-51-A5D1AD73","assetsServer":"https://assets.healthline.com","algoliaAppId":"7835BOM3SG","algoliaSearchApiKey":"e34a454de65f33ce5820690f9032bcaf","algoliaSearchIndex":"crawler_Prod Healthline","algoliaQuerySuggestionIndex":"crawler_Prod Healthline_query_suggestions","oneTrustOrgId":"50162747-1340-4ce9-8836-735e1fd65cc6"}; _comscore=[]; __comscoreParams=[{"c1":"2","c2":"38584006","cs_ucfr":"","cs_fpit":"c","cs_fpdm":"*null","cs_fpdt":"*null","options":{"enableFirstPartyCookie":true,"bypassUserConsentRequirementFor1PCookie":true,"url_append":"comscorekw=main"}}]; function __uspapi(cmd, apiVer, callback) { if (cmd === 'getUSPData') { callback({ version: '1', uspString: __uspapi.d.usprivacy || '1YNY', }, true); } } __uspapi.d = {"usprivacy":"1YNY","ccpaApplies":true}; !function(){if('PerformanceLongTaskTiming' in window){var g=window.__tti={e:[]};g.o=new PerformanceObserver(function(l){g.e=g.e.concat(l.getEntries())});g.o.observe({entryTypes:['longtask']})}}(); function EventListener(eventName, listenerId, data, pingData) { this.eventName = eventName; this.listenerId = listenerId; this.data = data; this.pingData = pingData; } /** * Custom gpc handler for ?isGpc */ const params = new URLSearchParams(document.location.search); if (params.get('isGpc') !== null) { navigator.globalPrivacyControl = true; } /* Cohesion Configs */ function tagular(...args) { tagular.q.push(args); } tagular.q = []; function preamp(...args) { preamp.q.push(args); } preamp.q = []; function cohesion(...args) { cohesion.q.push(args); } cohesion.q = []; const tagularConfigs = {"apiVersion":"v2/t","writeKey":"wk_1Tqf7EYzOKyxm4Gvq042rU0Uky0","sourceKey":"src_1Tqf7BF96WTbG5QbUndHWIgKoFo","domainWhitelist":["www.healthline.com","act.healthline.com","frontend-stage.healthline.com","act-stage.healthline.com","activation.healthline.com","activation-stage.healthline.com"],"cookieDomain":"healthline.com","multiparty":true,"reinforce":"https://www.healthline.com/navi","experimentalFeatures":{"flocEnabled":true},"eventSampling":{"eligibleEvents":["DomCompleted","PageScrolled"],"fireRate":25}}; if (HL.i.enabled) { /* Only suppress some tagular events for infinite scroll */ Object.assign(tagularConfigs, { beamHook(event) { /* Executed every time beam is called and passed the event */ /* eslint-disable-next-line no-underscore-dangle */ window._Tagular.config.suppressBeam = event['@type'] === 'redventures.usertracking.v3.PageScrolled'; } }) } const preampConfigs = HL.ga.contentType === 'brand-page' ? false : { ...{"siteId":"2ahYQ7GmZHnMGlBjvg6cFP"}, hooks: { /* Runs before Preamp requests a new decision */ beforeRun(cohesionConfig, done) { /* Adds k1 to custom Preamp values */ /* Allows Preamp experiences to be created based on the current K1 */ cohesionConfig.custom = { ...cohesionConfig.custom, k1: HL.ga.k1, }; done(); }, beforePlacement(placement, done) { const interval = setInterval(() => { if (window.afterMPD) { /* Defer preamp rendering until we have injected all MPDs as those */ /* need to be in the DOM for Preamp to inject into. */ afterMPD(done); clearInterval(interval); } },500) }, } }; /* eslint-disable-next-line no-underscore-dangle */ window._Cohesion = { k: 'cohesion', tagular: tagularConfigs, preamp: preampConfigs }; window._Tagular = { k: 'tagular' }; window._Preamp = { k: 'preamp', start: new Date(), docReady: true }; window._Fuse = { k: 'fuse', docReady: false }; window.tagular = tagular; window.preamp = preamp; window.fuse = () => {}; window.cohesion = cohesion; </script><script> var AdBridg = AdBridg || {cmd: []}; </script><script src="//prod.adspsp.com/adb.2418030.min.js" async=""></script><script src="https://securepubads.g.doubleclick.net/tag/js/gpt.js" async=""></script><script src="https://pub.doubleverify.com/dvtag/20447058/DV1208979/pub.js" async=""></script><script> var skimlinks_settings = { skimlinks_exclude: ['www.amazon.com', 'amazon.com', 'amzn.to'] }; </script><script src="https://rvo-cohesion.healthline.com/cohesion/cohesion-tpo.min.js?cDomain=healthline.com" async=""></script><link href="https://c.aps.amazon-adsystem.com" rel="preconnect" crossorigin="true"/><script src="https://c.aps.amazon-adsystem.com/apstag.js" async=""></script><script>module={};__NEXT_DATA__={"buildId":"b4a658d5-9338-4cd3-9e5d-9d0a6ca8e30c","props":{"ga":{"k1":"marijuanause","k2":"substanceuse","kmeta":"eczema-predictive-aq,nsclc-predictive-aq,obesity-predictive-aq,bipolar-predictive-aq-1,bipolar-predictive-aq,vraylar24bp","contentType":"Tabbed Article","author":"Crystal Raypole","articleType":"regular","sponsoredProgramId":"","articleId":"wp-96687","mainContentCategoryTags":"","publishedDate":"2019-05-17","updatedDate":"2024-04-02","medReviewer":"Alan Carter, Pharm.D.","category":"Uncategorized","subcategory":"","trackingTerms":"","ek1":"2451d4dc77dcf393b196757b","ekmeta":"2c53dcd070c8bf8da286627765df54e15bfb829f,2743c5d97e84e28fb5876f7d72c24bf213b792,2652c3c674ddebd0a091637a6fc849fe48b3ce8f25,2b59d6da71c8e0d0a091637a6fc849fe48b3ce8f251715,2b59d6da71c8e0d0a091637a6fc849fe48b3ce8f25,3f42c7cc71c8e0cfe48176,","contentForm":"Non-Head Term","type":"healthfeature"},"lang":"en","data":{"k1":"marijuanause","sideEffectsWidget":{},"livedExperience":{},"shareYourExperience":{},"drugSavingsData":null,"comments":[],"topComments":[],"id":"wp-96687","title":["A Simple Guide to the Endocannabinoid System"],"articleHistory":{"2019-05-17":{"updateReason":[],"authors":"Crystal Raypole","editor":"Judy Lee","medicallyReviewedBy":"Alan Carter, PharmD"}},"updateReason":[],"isFeature":false,"isPaidMedia":false,"isEditorialPaidMedia":false,"isTransactionalPaidMedia":false,"authors":[{"id":211,"name":{"display":"Crystal Raypole","first":"Crystal","last":"Raypole"},"link":"/authors/crystal-raypole","type":{"value":"author","label":"Author"},"nid":"","specialties":[],"guestTitle":"","bio":{"text":"\u003cp\u003eCrystal Raypole\u0026#8217;s work appears on Healthline, and she\u0026#8217;s previously worked as a writer and editor for GoodTherapy. Her interests include Japanese language and translation, cooking, natural sciences, sex positivity, and mental health. In particular, she’s committed to helping decrease stigma around mental health issues. She hopes to someday write fiction — if she can stop reading fiction long enough to write more than a few chapters of anything.\u003c/p\u003e\n"},"avatar":{"title":"","width":200,"height":200,"src":"https://post.healthline.com/wp-content/uploads/2020/01/200x200_Crystal_Raypole.png"},"bioBlurb":{"nodes":["Crystal Raypole’s work appears on Healthline, and she’s previously worked as a writer and editor for GoodTherapy. Her interests include Japanese language and…"]}}],"medicalReviewers":[{"id":115,"name":{"display":"Alan Carter, Pharm.D.","first":"Alan","last":"Carter, PharmD"},"userLogin":"achealthline","links":{"website":"","facebook":"","linkedin":"https://www.linkedin.com/in/alancarterpharmd/","twitter":"","instagram":"","tiktok":""},"link":"/reviewers/alan-carter-pharmd","type":{"value":"medical_reviewer","label":"Medical Advisor"},"nid":"122506","specialties":[],"guestTitle":"","bio":{"text":"\u003cp style=\"text-align: left;\"\u003e\u003cem\u003eThis individual is no longer a medical reviewer in our network. The credentials and contact information reflected here may not be current.\u003c/em\u003e\u003c/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eDr. Alan Carter is a clinical pharmacist with interests in medical research, pharmacy practice, and medication formulary management. He is an independent contracted medical director for pharmaceutical development, clinical pharmacy specialist, and adjunct clinical assistant professor of pharmacy.\u003c/span\u003e\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eEducation\u003c/strong\u003e\u003c/p\u003e\n\u003cul\u003e\n\u003cli style=\"font-weight: 400;\" aria-level=\"1\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eUniversity of Missouri \u0026#8211; Kansas City, BS, PharmD\u003c/span\u003e\u003c/li\u003e\n\u003c/ul\u003e\n\u003cp\u003e\u003cstrong\u003eCertifications\u003c/strong\u003e\u003c/p\u003e\n\u003cul\u003e\n\u003cli aria-level=\"1\"\u003eLicensed Pharmacist\u003c/li\u003e\n\u003cli style=\"font-weight: 400;\" aria-level=\"1\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eKansas Board of Pharmacy\u003c/span\u003e\u003c/li\u003e\n\u003cli style=\"font-weight: 400;\" aria-level=\"1\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eMissouri Board of Pharmacy\u003c/span\u003e\u003c/li\u003e\n\u003cli style=\"font-weight: 400;\" aria-level=\"1\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eCertified Immunizing Pharmacist\u003c/span\u003e\u003c/li\u003e\n\u003cli style=\"font-weight: 400;\" aria-level=\"1\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eCertified Smoking Cessation Specialist\u003c/span\u003e\u003c/li\u003e\n\u003c/ul\u003e\n\u003cp\u003e\u003cstrong\u003eProfessional Accomplishments\u003c/strong\u003e\u003c/p\u003e\n\u003cul\u003e\n\u003cli style=\"font-weight: 400;\" aria-level=\"1\"\u003e\u003cspan style=\"font-weight: 400;\"\u003ePublished 20 journal articles to date, performs medical journal peer review, and serves on many professional committees and boards\u003c/span\u003e\u003c/li\u003e\n\u003cli style=\"font-weight: 400;\" aria-level=\"1\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eAwarded the Pharmacy Career Achievement Award by the University of Missouri \u0026#8211; Kansas City, 2019\u003c/span\u003e\u003c/li\u003e\n\u003cli style=\"font-weight: 400;\" aria-level=\"1\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eServed as principal investigator for the National Institutes of Health, NINDS BRAIN Initiative for Neurological Drug Development, 2015-2018\u003c/span\u003e\u003c/li\u003e\n\u003c/ul\u003e\n\u003cp\u003e\u003cstrong\u003eAffiliations\u003c/strong\u003e\u003c/p\u003e\n\u003cul\u003e\n\u003cli style=\"font-weight: 400;\" aria-level=\"1\"\u003e\u003ca href=\"https://pharmacy.umkc.edu/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eUniversity of Missouri-Kansas City School of Pharmacy\u003c/span\u003e\u003c/a\u003e\u003c/li\u003e\n\u003cli style=\"font-weight: 400;\" aria-level=\"1\"\u003e\u003ca href=\"https://www.philambdasigma.org/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003ePhi Lambda Sigma Pharmacy Leadership Society\u003c/span\u003e\u003c/a\u003e\u003c/li\u003e\n\u003c/ul\u003e\n"},"avatar":{"title":"","width":500,"height":500,"src":"https://post.healthline.com/wp-content/uploads/2022/01/Alan-Carter-500x500-Bio.png"},"bioBlurb":{"nodes":["This individual is no longer a medical reviewer in our network. The credentials and contact information reflected here may not be current. Dr. Alan Carter is a…"]}}],"editors":[{"role":"Editor","name":{"display":"Judy Lee"}}],"pinterestImage":{"path":"https://media.post.rvohealth.io/wp-content/uploads/2019/04/Doctor_Talk_Female_Laptop-732x549-Thumbnail.jpg"},"isMedicare":false,"isBlog":false,"publishSource":"wordpress","isAmpSupported":false,"categories":[{"name":"Uncategorized","slug":"uncategorized","link":"/uncategorized","children":[]}],"language":{"en":"https://www.healthline.com/health/endocannabinoid-system/","x-default":"https://www.healthline.com/health/endocannabinoid-system/","current":"en"},"lang":"en","links":[],"colorScheme":"default","isContentSeries":false,"brandCTAs":[],"clusterNavLinks":[],"clusterUrls":[],"clusterLinks":{},"pathingTilesData":{"pathingTiles":[{"title":"Diabetes Essentials","url":"https://www.healthline.com/type-2-diabetes/essentials"},{"title":"What To Eat","url":"https://www.healthline.com/type-2-diabetes/what-to-eat"},{"title":"Medications","url":"https://www.healthline.com/type-2-diabetes/medications"},{"title":"Blood Sugar \u0026 A1C","url":"https://www.healthline.com/type-2-diabetes/essentials/blood-sugar-management"}]},"pathingCardsData":{},"inArticlePathingCardsData":[],"quantitativeTrustData":{"cbd-all":{"metrics":[{"description":"CBD products evaluated","count":"950+"},{"description":"CBD brands evaluated","count":"190+"},{"description":"CBD products personally tested","count":"115+"}],"explanationTitle":"How we vet CBD products","explanationDescription":"\u003cp\u003eOur \u003ca href=\"https://www.healthline.com/about/vet-brands-and-products\"\u003eMedical Standards and Insights team\u003c/a\u003e has carefully researched and vetted over 11,000 products and services. We fact-check health claims, evaluate ingredients, and look into each brand’s reputation before sharing products and services on Healthline.\u003c/p\u003e\u003cp\u003eTo choose the brands on this page, we considered all the CBD brands that passed our vetting process. Then, we personally tested some of them to narrow down our list even further. \u003ca href=\"https://www.healthline.com/health/how-we-test-cbd\"\u003eRead more about how we test CBD products.\u003c/a\u003e\u003c/p\u003e"},"cbd-gummies":{"metrics":[{"description":"CBD gummies evaluated","count":"150+"},{"description":"CBD gummy brands evaluated","count":"50+"},{"description":"CBD gummies personally tested","count":"20"}],"explanationTitle":"How we vet CBD gummies","explanationDescription":"\u003cp\u003eOur \u003ca href=\"https://www.healthline.com/about/vet-brands-and-products\"\u003eMedical Standards and Insights team\u003c/a\u003e has carefully researched and vetted over 11,000 products and services. We fact-check health claims, evaluate ingredients, and look into each brand’s reputation before sharing products and services on Healthline.\u003c/p\u003e\u003cp\u003eTo choose the products on this page, we considered all the CBD gummies that passed our vetting process. Then, we personally tested some of them to narrow down our list even further. \u003ca href=\"https://www.healthline.com/health/how-we-test-cbd\"\u003eRead more about how we test CBD products.\u003c/a\u003e\u003c/p\u003e"},"cbd-oils":{"metrics":[{"description":"CBD oils \u0026 tinctures evaluated","count":"460+"},{"description":"CBD oil \u0026 tincture brands evaluated","count":"85+"},{"description":"CBD oils \u0026 tinctures personally tested","count":"25"}],"explanationTitle":"How we evaluate CBD oils and tinctures","explanationDescription":"\u003cp\u003eOur \u003ca href=\"https://www.healthline.com/about/vet-brands-and-products\"\u003eMedical Standards and Insights team\u003c/a\u003e has carefully researched and vetted over 11,000 products and services. We fact-check health claims, evaluate ingredients, and look into each brand’s reputation before sharing products and services on Healthline.\u003c/p\u003e\u003cp\u003eTo choose the products on this page, we considered all the CBD oils that passed our vetting process. Then, we personally tested some of them to narrow down our list even further. \u003ca href=\"https://www.healthline.com/health/how-we-test-cbd\"\u003eRead more about how we test CBD products.\u003c/a\u003e\u003c/p\u003e"},"cbd-lotions-creams":{"metrics":[{"description":"CBD lotions, creams, \u0026 balms evaluated","count":"150+"},{"description":"brands of CBD lotions, creams, \u0026 balms evaluated","count":"75+"},{"description":"CBD lotions, creams, \u0026 balms personally tested","count":"20+"}],"explanationTitle":"How we evaluate CBD lotions, creams, and balms","explanationDescription":"\u003cp\u003eOur \u003ca href=\"https://www.healthline.com/about/vet-brands-and-products\"\u003eMedical Standards and Insights team\u003c/a\u003e has carefully researched and vetted over 11,000 products and services. We fact-check health claims, evaluate ingredients, and look into each brand’s reputation before sharing products and services on Healthline.\u003c/p\u003e\u003cp\u003eTo choose the products on this page, we considered all the CBD lotions, creams, and balms that passed our vetting process. Then, we personally tested some of them to narrow down our list even further. \u003ca href=\"https://www.healthline.com/health/how-we-test-cbd\"\u003eRead more about how we test CBD products.\u003c/a\u003e\u003c/p\u003e"},"cbd-capsules":{"metrics":[{"description":"CBD products evaluated","count":"950+"},{"description":"CBD capsules evaluated","count":"75+"},{"description":"CBD capsule brands evaluated","count":"30+"}],"explanationTitle":"How we evaluate CBD capsules","explanationDescription":"\u003cp\u003eOur \u003ca href=\"https://www.healthline.com/about/vet-brands-and-products\"\u003eMedical Standards and Insights team\u003c/a\u003e has carefully researched and vetted over 11,000 products and services. We fact-check health claims, evaluate ingredients, and look into each brand’s reputation before sharing products and services on Healthline.\u003c/p\u003e\u003cp\u003eTo choose the products on this page, we considered all the CBD capsules that passed our vetting process. Then, we personally tested some of them to narrow down our list even further. \u003ca href=\"https://www.healthline.com/health/how-we-test-cbd\"\u003eRead more about how we test CBD products.\u003c/a\u003e\u003c/p\u003e"},"online-therapy":{"metrics":[{"description":"online therapy platforms evaluated","count":"35+"},{"description":"online therapy platforms personally tested","count":"12"}],"explanationTitle":"How we evaluate online therapy platforms","explanationDescription":"\u003cp\u003eOur \u003ca href=\"https://www.healthline.com/about/vet-brands-and-products\"\u003eMedical Standards and Insights team\u003c/a\u003e has carefully researched and vetted over 11,000 products and services. We evaluate services for consistency with standards of care and best practices, and we look into each brand’s reputation before sharing products and services on Healthline.\u003c/p\u003e\u003cp\u003eTo choose the online therapy platforms on this page, we considered all the platforms that passed our vetting process. Then, we personally tested some of them to narrow down our list even further.\u003c/p\u003e"},"meal-delivery":{"metrics":[{"description":"meal delivery services evaluated","count":"70+"},{"description":"meal delivery services personally tested","count":"35+"}],"explanationTitle":"How we evaluate meal delivery services","explanationDescription":"\u003cp\u003eOur \u003ca href=\"https://www.healthline.com/about/vet-brands-and-products\"\u003eMedical Standards and Insights team\u003c/a\u003e has carefully researched and vetted over 11,000 products and services. We fact-check health claims, evaluate menus and ingredients, and look into each brand’s reputation before sharing products and services on Healthline.\u003c/p\u003e\u003cp\u003eTo choose the meal delivery services on this page, we considered all the services that passed our vetting process. Then, we personally tested some of them to narrow down our list even further. \u003ca href=\"https://www.healthline.com/nutrition/how-we-test-meal-kits\"\u003eRead more about how we test meal delivery services.\u003c/a\u003e\u003c/p\u003e"},"protein-powders":{"metrics":[{"description":"protein powders evaluated by our medical standards team","count":"75"},{"description":"protein powders met our criteria","count":"58"},{"description":"protein powders personally tested by our team","count":"19"}],"explanationTitle":"How we evaluate protein powders","explanationDescription":"\u003cp\u003eOur \u003ca href=\"https://www.healthline.com/about/vet-brands-and-products\"\u003eMedical Standards and Insights team\u003c/a\u003e has carefully researched and vetted over 11,000 products and services. We fact-check health claims, evaluate ingredients, and look into each brand’s reputation before sharing products and services on Healthline.\u003c/p\u003e\u003cp\u003eTo choose the products on this page, we considered all the protein powders that passed our vetting process. Then, we personally tested some of them to narrow down our list even further.\u003c/p\u003e"},"glp1-telehealth":{"metrics":[{"description":"telehealth companies evaluated","count":"200+"},{"description":"online GLP-1 providers evaluated","count":"13+"}],"explanationTitle":"How we evaluate online GLP-1 services","explanationDescription":"\u003cp\u003eOur \u003ca href=\"https://www.healthline.com/about/vet-brands-and-products\"\u003eMedical Standards and Insights team\u003c/a\u003e has carefully researched and vetted over 11,000 products and services. We evaluate services for consistency with standards of care and best practices, and we look into each brand’s reputation before sharing products and services on Healthline.\u003c/p\u003e\u003cp\u003eTo choose the services on this page, we considered all the GLP-1 services that passed our vetting process. Then, we looked at availability, cost, and the additional resources each service provides to narrow down our list even further.\u003c/p\u003e"},"all-vitamins":{"metrics":[{"description":"vitamins, minerals, and supplements evaluated","count":"1320+"},{"description":"vitamins, minerals, and supplements personally tested","count":"95+"},{"description":"vitamin, mineral, and supplement brands personally tested","count":"40+"}],"explanationTitle":"How we evaluate vitamins, minerals, and supplements","explanationDescription":"\u003cp\u003eOur \u003ca href=\"https://www.healthline.com/about/vet-brands-and-products\"\u003eMedical Standards and Insights team\u003c/a\u003e has carefully researched and vetted over 11,000 products and services. We fact-check health claims, evaluate ingredients, and look into each brand’s reputation before sharing products and services on Healthline.\u003c/p\u003e\u003cp\u003eTo choose the brands on this page, we considered all the vitamin brands that passed our vetting process. Then, we personally tested some of them to narrow down our list even further.\u003c/p\u003e"},"multivitamins":{"metrics":[{"description":"multivitamins evaluated","count":"100+"},{"description":"multivitamin brands evaluated","count":"55+"},{"description":"multivitamins personally tested","count":"20+"}],"explanationTitle":"How we evaluate multivitamins","explanationDescription":"\u003cp\u003eOur \u003ca href=\"https://www.healthline.com/about/vet-brands-and-products\"\u003eMedical Standards and Insights team\u003c/a\u003e has carefully researched and vetted over 11,000 products and services. We fact-check health claims, evaluate ingredients, and look into each brand’s reputation before sharing products and services on Healthline.\u003c/p\u003e\u003cp\u003eTo choose the products on this page, we considered all the multivitamins that passed our vetting process. Then, we personally tested some of them to narrow down our list even further.\u003c/p\u003e"},"prenatals":{"metrics":[{"description":"vitamins, minerals, and supplements evaluated","count":"1320+"},{"description":"prenatal vitamins evaluated","count":"35+"},{"description":"prenatal vitamin brands evaluated","count":"30+"}],"explanationTitle":"How we evaluate prenatals","explanationDescription":"\u003cp\u003eOur \u003ca href=\"https://www.healthline.com/about/vet-brands-and-products\"\u003eMedical Standards and Insights team\u003c/a\u003e has carefully researched and vetted over 11,000 products and services. We fact-check health claims, evaluate ingredients, and look into each brand’s reputation before sharing products and services on Healthline.\u003c/p\u003e\u003cp\u003eTo choose the products on this page, we considered all the prenatal vitamins that passed our vetting process. Then, we personally tested some of them to narrow down our list even further.\u003c/p\u003e"},"probiotics":{"metrics":[{"description":"vitamins, minerals, and supplements evaluated","count":"1320+"},{"description":"probiotic supplements evaluated","count":"55"},{"description":"probiotic brands evaluated","count":"35"}],"explanationTitle":"How we evaluate probiotics","explanationDescription":"\u003cp\u003eOur \u003ca href=\"https://www.healthline.com/about/vet-brands-and-products\"\u003eMedical Standards and Insights team\u003c/a\u003e has carefully researched and vetted over 11,000 products and services. We fact-check health claims, evaluate ingredients, and look into each brand’s reputation before sharing products and services on Healthline.\u003c/p\u003e\u003cp\u003eTo choose the products on this page, we considered all the probiotics that passed our vetting process. Then, we personally tested some of them to narrow down our list even further.\u003c/p\u003e"},"vitamin-d":{"metrics":[{"description":"vitamins, minerals, and supplements evaluated","count":"1320+"},{"description":"vitamin D supplements evaluated","count":"40+"},{"description":"vitamin D brands evaluated","count":"25+"}],"explanationTitle":"How we evaluate vitamin D supplements","explanationDescription":"\u003cp\u003eOur \u003ca href=\"https://www.healthline.com/about/vet-brands-and-products\"\u003eMedical Standards and Insights team\u003c/a\u003e has carefully researched and vetted over 11,000 products and services. We fact-check health claims, evaluate ingredients, and look into each brand’s reputation before sharing products and services on Healthline.\u003c/p\u003e\u003cp\u003eTo choose the products on this page, we considered all the vitamin D supplements that passed our vetting process. Then, we personally tested some of them to narrow down our list even further.\u003c/p\u003e"},"creatine":{"metrics":[{"description":"creatine supplements evaluated by our medical standards team","count":"35"},{"description":"creatine supplements met our criteria","count":"28"},{"description":"creatine supplements personally tested by our team","count":"9"}],"explanationTitle":"How we evaluate creatine supplements","explanationDescription":"\u003cp\u003eOur \u003ca href=\"https://www.healthline.com/about/vet-brands-and-products\"\u003eMedical Standards and Insights team\u003c/a\u003e has carefully researched and vetted over 11,000 products and services. We fact-check health claims, evaluate ingredients, and look into each brand’s reputation before sharing products and services on Healthline.\u003c/p\u003e\u003cp\u003eTo choose the products on this page, we considered all the creatine supplements that passed our vetting process. Then, we personally tested some of them to narrow down our list even further.\u003c/p\u003e"},"mattresses":{"metrics":[{"description":"mattresses evaluated","count":"250+"},{"description":"mattress brands evaluated","count":"80+"}],"explanationTitle":"How we evaluate mattresses","explanationDescription":"\u003cp\u003eOur \u003ca href=\"https://www.healthline.com/about/vet-brands-and-products\"\u003eMedical Standards and Insights team\u003c/a\u003e has carefully researched and vetted over 11,000 products and services. We fact-check health claims, evaluate materials, and look into each brand’s reputation before sharing products and services on Healthline.\u003c/p\u003e\u003cp\u003eTo choose the products on this page, we considered all the mattresses that passed our vetting process. Then, we \u003ca href=\"https://www.healthline.com/health/sleep/healthline-scores-how-we-rate-mattresses\"\u003escored each mattress\u003c/a\u003e to narrow down our list even further.\u003c/p\u003e"},"pillows":{"metrics":[{"description":"pillows evaluated","count":"210"},{"description":"pillow brands evaluated","count":"140+"}],"explanationTitle":"How we evaluate pillows","explanationDescription":"\u003cp\u003eOur \u003ca href=\"https://www.healthline.com/about/vet-brands-and-products\"\u003eMedical Standards and Insights team\u003c/a\u003e has carefully researched and vetted over 11,000 products and services. We fact-check health claims, evaluate materials, and look into each brand’s reputation before sharing products and services on Healthline.\u003c/p\u003e\u003cp\u003eTo choose the products on this page, we considered all the pillows that passed our vetting process.\u003c/p\u003e"},"ed-telehealth":{"metrics":[{"description":"telehealth companies evaluated","count":"200+"},{"description":"online ED treatment providers evaluated","count":"20+"}],"explanationTitle":"How we evaluate online ED services","explanationDescription":"\u003cp\u003eOur \u003ca href=\"https://www.healthline.com/about/vet-brands-and-products\"\u003eMedical Standards and Insights team\u003c/a\u003e has carefully researched and vetted over 11,000 products and services. We evaluate services for consistency with standards of care and best practices, and we look into each brand’s reputation before sharing products and services on Healthline.\u003c/p\u003e\u003cp\u003eTo choose the services on this page, we considered all the ED treatment services that passed our vetting process. Then, we \u003ca href=\"https://www.healthline.com/health/healthline-scores-how-we-evaluate-mens-telehealth-platforms\"\u003escored each service\u003c/a\u003e to narrow down our list even further.\u003c/p\u003e"},"birth-control-telehealth":{"metrics":[{"description":"telehealth companies evaluated","count":"200+"},{"description":"online birth control providers evaluated","count":"14"}],"explanationTitle":"How we evaluate online birth control services","explanationDescription":"\u003cp\u003eOur \u003ca href=\"https://www.healthline.com/about/vet-brands-and-products\"\u003eMedical Standards and Insights team\u003c/a\u003e has carefully researched and vetted over 11,000 products and services. We evaluate services for consistency with standards of care and best practices, and we look into each brand’s reputation before sharing products and services on Healthline.\u003c/p\u003e\u003cp\u003eTo choose the services on this page, we considered all the birth control services that passed our vetting process. Then, we \u003ca href=\"https://www.healthline.com/health/how-we-review-birth-control\"\u003escored each service\u003c/a\u003e to narrow down our list even further.\u003c/p\u003e"},"hemp":{"metrics":[{"description":"Hemp brands evaluated","count":"230+"},{"description":"Hemp brands met our criteria","count":"57"}],"explanationTitle":"How we evaluate hemp products","explanationDescription":"\u003cp\u003eOur Medical Standards and Insights team has carefully researched and vetted over 11,000 products and services. We fact-check health claims, evaluate ingredients, and look into each brand’s reputation before sharing products and services on Healthline. The brand we feature in this article has passed our strict vetting process and has been thoroughly tested by our reviewers. \u003ca href=\"https://www.healthline.com/about/vet-brands-and-products\"\u003eRead more about how we vet brands and products.\u003c/a\u003e\u003c/p\u003e"}},"isPrependRecipeH2":false,"recipes":[],"hideTabs":false,"tabs":[{"id":"_noHeaderPrefixedContent","title":null,"header":null,"body":[{"tagName":"div","source":"\u003cp class=\"css-w2pt6r\"\u003eThe endocannabinoid system (ECS) is a complex cell-signaling system that helps regulate your body functions, including sleep and mood, among others.\u003c/p\u003e"},{"tagName":"p","source":"It was identified in the early 1990s by researchers exploring THC, a well-known cannabinoid. Cannabinoids are compounds found in \u003ca href=\"https://www.healthline.com/health/what-is-cannabis\" class=\"content-link css-1c2ok3c\"\u003ecannabis\u003c/a\u003e."},{"tagName":"div","attributes":{"data-preamp":"serena-chatbot"},"source":""},{"tagName":"p","source":"Experts are still trying to fully understand the ECS. But so far, we know it plays role in regulating a range of functions and processes, including:"},{"tagName":"ul","source":"\u003cli\u003esleep\u003c/li\u003e\u003cli\u003emood\u003c/li\u003e\u003cli\u003eappetite\u003c/li\u003e\u003cli\u003ememory\u003c/li\u003e\u003cli\u003ereproduction and fertility\u003c/li\u003e"},{"tagName":"p","source":"The ECS exists and is active in your body even if you don’t use cannabis. "},{"tagName":"p","source":"Read on to learn more about the ECS including how it works and interacts with cannabis."}]},{"id":"how-it-works","title":"How it works","isCollapsable":false,"header":["How does it work?"],"body":[{"tagName":"p","source":"The ECS involves three core components: endocannabinoids, receptors, and enzymes."},{"tagName":"h3","source":"\u003cstrong\u003eEndocannabinoids\u003c/strong\u003e"},{"tagName":"p","source":"Endocannabinoids, also called endogenous cannabinoids, are molecules made by your body. They’re similar to cannabinoids, but they’re produced by your body."},{"tagName":"p","source":"Experts have identified two key endocannabinoids so far:"},{"tagName":"ul","source":"\u003cli\u003e anandamide (AEA)\u003c/li\u003e\u003cli\u003e 2-arachidonoylglyerol (2-AG)\u003c/li\u003e"},{"tagName":"p","source":"These help keep internal functions running smoothly. Your body produces them as needed, making it difficult to know what typical levels are for each. "},{"tagName":"h3","source":"Endocannabinoid receptors"},{"tagName":"p","source":"These receptors are found throughout your body. Endocannabinoids bind to them in order to signal that the ECS needs to take action."},{"tagName":"p","source":"There are two main endocannabinoid receptors:"},{"tagName":"ul","source":"\u003cli\u003eCB1 receptors, which are mostly found in the central nervous system\u003c/li\u003e\u003cli\u003eCB2 receptors, which are mostly found in your peripheral nervous system, especially immune cells\u003c/li\u003e"},{"tagName":"p","source":"Endocannabinoids can bind to either receptor. The effects that result depend on where the receptor is located and which endocannabinoid it binds to. "},{"tagName":"p","source":"For example, endocannabinoids might target CB1 receptors in a spinal nerve to relieve pain. Others might bind to a CB2 receptor in your immune cells to signal that your body’s experiencing inflammation, a common sign of autoimmune disorders. "},{"tagName":"h3","source":"Enzymes"},{"tagName":"p","source":"Enzymes are responsible for breaking down endocannabinoids once they’ve carried out their function."},{"tagName":"p","source":"There are two main enzymes responsible for this:"},{"tagName":"ul","source":"\u003cli\u003efatty acid amide hydrolase, which breaks down AEA\u003c/li\u003e\u003cli\u003emonoacylglycerol acid lipase, which typically breaks down 2-AG\u003c/li\u003e"}]},{"id":"functions","title":"Functions","isCollapsable":false,"header":["What are its functions?"],"body":[{"tagName":"p","source":"The ECS is complicated, and experts haven’t yet determined exactly how it works or all of its potential functions. "},{"tagName":"p","source":"\u003chl-trusted-source source=\"PubMed Central\" rationale=\"Highly respected database from the National Institutes of Health\"\u003e\u003ca href=\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877694/\" target=\"_blank\" rel=\"noopener noreferrer\" class=\"content-link css-1c2ok3c\"\u003eResearch\u003c/a\u003e\u003c/hl-trusted-source\u003e has linked the ECS to the following processes: "},{"tagName":"ul","source":"\u003cli\u003eappetite and digestion\u003c/li\u003e\u003cli\u003emetabolism \u003c/li\u003e\u003cli\u003e\u003ca href=\"https://www.healthline.com/health/chronic-pain\" class=\"content-link css-1c2ok3c\"\u003echronic pain\u003c/a\u003e\u003c/li\u003e\u003cli\u003e\u003ca href=\"https://www.healthline.com/health/chronic-inflammation\" class=\"content-link css-1c2ok3c\"\u003einflammation\u003c/a\u003e and other immune system responses\u003c/li\u003e\u003cli\u003emood \u003c/li\u003e\u003cli\u003elearning and memory \u003c/li\u003e\u003cli\u003emotor control\u003c/li\u003e\u003cli\u003esleep\u003c/li\u003e\u003cli\u003ecardiovascular system function \u003c/li\u003e\u003cli\u003emuscle formation \u003c/li\u003e\u003cli\u003ebone remodeling and growth\u003c/li\u003e\u003cli\u003eliver function\u003c/li\u003e\u003cli\u003ereproductive system function\u003c/li\u003e\u003cli\u003e\u003ca href=\"https://www.healthline.com/health/stress\" class=\"content-link css-1c2ok3c\"\u003estress\u003c/a\u003e\u003c/li\u003e\u003cli\u003eskin and nerve function \u003c/li\u003e"},{"tagName":"p","source":"These functions all contribute to homeostasis, which refers to stability of your internal environment. For example, if an outside force, such as pain from an injury or a fever, throws off your body’s homeostasis, your ECS kicks in to help your body return to its ideal operation. "},{"tagName":"p","source":"Today, experts believe that maintaining homeostasis if the primary role of the ECS."}]},{"id":"thc","title":"THC","isCollapsable":false,"header":["How does THC interact with the ECS?"],"body":[{"tagName":"p","source":"Tetrahydrocannabinol (THC) is one of the main cannabinoids found in cannabis. It’s the compound that gets you “high.” "},{"tagName":"p","source":"Once in your body, THC interacts with your ECS by binding to receptors, just like endocannabinoids. It’s powerful partly because it can bind to both CB1 and CB2 receptors. "},{"tagName":"p","source":"This allows it to have a range of effects on your body and mind, some more desirable than others. For example, THC may help to reduce pain and stimulate your appetite. But it can also cause paranoia and anxiety in some cases. "},{"tagName":"p","source":"Experts are currently looking into ways to produce synthetic THC cannabinoids that interact with the ECS in only beneficial ways. "}]},{"id":"cbd","title":"CBD","isCollapsable":false,"header":["How does CBD interact with the ECS?"],"body":[{"tagName":"p","source":"The other major cannabinoid found in cannabis is cannabidiol (CBD). Unlike THC, CBD doesn’t make you “high” and typically doesn’t cause any negative effects. "},{"tagName":"p","source":"Experts aren’t completely sure how CBD interacts with the ECS. But they do know that it doesn’t bind to CB1 or CB2 receptors the way THC does. "},{"tagName":"p","source":"Instead, many believe it works by preventing endocannabinoids from being broken down. This allows them to have more of an effect on your body. Others believe that CBD binds to a receptor that hasn’t been discovered yet. "},{"tagName":"p","source":"While the details of how it works are still under debate, research suggests that CBD can help with pain, nausea, and other symptoms associated with multiple conditions. "}]},{"id":"deficiency","title":"Deficiency","isCollapsable":false,"header":["What about endocannabinoid deficiency?"],"body":[{"tagName":"p","source":"Some experts believe in a theory known as clinical endocannabinoid deficiency (CECD). This theory suggests that low endocannabinoid levels in your body or ECS dysfunction can contribute to the development of certain conditions."},{"tagName":"p","source":"A \u003chl-trusted-source source=\"PubMed Central\" rationale=\"Highly respected database from the National Institutes of Health\"\u003e\u003ca href=\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576607/\" target=\"_blank\" rel=\"noopener noreferrer\" class=\"content-link css-1c2ok3c\"\u003e2016 article\u003c/a\u003e\u003c/hl-trusted-source\u003e reviewing over 10 years of research on the subject suggests the theory could explain why some people develop \u003ca href=\"https://www.healthline.com/health/migraine\" class=\"content-link css-1c2ok3c\"\u003emigraine\u003c/a\u003e, \u003ca href=\"https://www.healthline.com/health/fibromyalgia\" class=\"content-link css-1c2ok3c\"\u003efibromyalgia\u003c/a\u003e, and \u003ca href=\"https://www.healthline.com/health/irritable-bowel-syndrome\" class=\"content-link css-1c2ok3c\"\u003eirritable bowel syndrome\u003c/a\u003e. "},{"tagName":"p","source":"None of these conditions have a clear underlying cause. They’re also often resistant to treatment and sometimes occur alongside each other. "},{"tagName":"p","source":"If CECD does play any kind of role in these conditions, targeting the ECS or endocannabinoid production could be the missing key to treatment, but more research is needed."}]},{"id":"takeaway","title":"Takeaway","isCollapsable":false,"header":["The bottom line"],"body":[{"tagName":"p","source":"The ECS plays a big role in keeping your internal processes stable. But there’s still a lot we don’t know about it. As experts develop a better understanding of the ECS, it could eventually hold the key to treating several conditions. "}]}],"hasAffiliateLinks":false,"affiliates":[],"propsFor":{"articleResources":[{"displayLink":"1021/cr0782067","link":"https://doi.org/10.1021%2Fcr0782067","title":{"tagName":"span","source":"Ahn K, et al. (2008). Enzymatic pathways that regulate endocannabinoid signaling in the nervous system. DOI:"}},{"displayLink":"ncbi.nlm.nih.gov/pmc/articles/PMC3997295","link":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997295","title":{"tagName":"span","source":"Alger BE. (2013). Getting high on the endocannabinoid system."}},{"displayLink":"drugabuse.gov/publications/brain-power/grades-6-9/weeding-out-grass-module-4/background","link":"https://www.drugabuse.gov/publications/brain-power/grades-6-9/weeding-out-grass-module-4/background","title":{"tagName":"span","source":"Background: Marijuana. (2007)."}},{"displayLink":"who.int/medicines/access/controlled-substances/5.2_CBD.pdf","link":"https://www.who.int/medicines/access/controlled-substances/5.2_CBD.pdf","title":{"tagName":"span","source":"Cannabidiol (CBD) Pre-review report. (2017)."}},{"displayLink":"cancer.gov/about-cancer/treatment/cam/patient/cannabis-pdq?redirect=true","link":"https://www.cancer.gov/about-cancer/treatment/cam/patient/cannabis-pdq?redirect=true","title":{"tagName":"span","source":"Cannabis and cannabinoids. (2019)."}},{"displayLink":"health.state.mn.us/people/cannabis/docs/rulemaking/endocannabinoidbrief.pdf","link":"https://www.health.state.mn.us/people/cannabis/docs/rulemaking/endocannabinoidbrief.pdf","title":{"tagName":"span","source":"Clinical endocannabinoid deficiency: Issue brief on clinical endocannabinoid deficiency. (2017). "}},{"displayLink":"2174/1381612820666140130212957","link":"https://doi.org/10.2174/1381612820666140130212957","title":{"tagName":"span","source":"De Laurentiis A, et al. (2014). Role of the endocannabinoid system in the neuroendocrine responses to inflammation. DOI:"}},{"displayLink":"1016/j.euroneuro.2016.08.007","link":"http://doi.org/10.1016/j.euroneuro.2016.08.007","title":{"tagName":"span","source":"de Morais H, et al. (2016). Anandamide reverses depressive-like behavior, neurochemical abnormalities and oxidative-stress parameters in streptozotocin-diabetic rats: Role of CB1 receptors. DOI:"}},{"displayLink":"ncbi.nlm.nih.gov/pmc/articles/PMC2633685","link":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2633685","title":{"tagName":"span","source":"Gomez M, et al. (2008). Cannabinoid signaling system."}},{"displayLink":"1016/j.brainresbull.2018.06.012","link":"https://doi.org/10.1016/j.brainresbull.2018.06.012","title":{"tagName":"span","source":"Gorzkiewicz A, et al. (2018). Brain endocannabinoid signaling exhibits remarkable complexity. DOI:"}},{"displayLink":"uclahealth.org/cannabis/human-endocannabinoid-system","link":"https://www.uclahealth.org/cannabis/human-endocannabinoid-system","title":{"tagName":"span","source":"Human endocannabinoid system. (n.d.)."}},{"displayLink":"1016/j.biopsych.2015.07.028","link":"https://doi.org/10.1016%2Fj.biopsych.2015.07.028","title":{"tagName":"span","source":"Lu H-C. (2015). An introduction to the endogenous cannabinoid system. DOI:"}},{"displayLink":"1016/j.tips.2015.02.008","link":"https://doi.org/10.1016%2Fj.tips.2015.02.008","title":{"tagName":"span","source":"Maccarrone M, et al. (2015). Endocannabinoid signaling at the periphery: 50 years after THC. DOI:"}},{"displayLink":"1124/pr.58.3.2","link":"https://doi.org/10.1124%2Fpr.58.3.2","title":{"tagName":"span","source":"Pacher P, et al. (2008). The endocannabinoid system as an emerging target of pharmacotherapy. DOI:"}},{"displayLink":"1089/can.2016.0009","link":"https://doi.org/10.1089%2Fcan.2016.0009","title":{"tagName":"span","source":"Russo EB. (2016). Clinical endocannabinoid deficiency reconsidered: Current research supports the theory in migraine, fibromyalgia, irritable bowel, and other treatment-resistant syndromes. DOI:"}},{"displayLink":"ncbi.nlm.nih.gov/pmc/articles/PMC3570572","link":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570572","title":{"tagName":"span","source":"Sharma P, et al. (2012). Chemistry, metabolism, and toxicology of cannabis: Clinical implications."}},{"displayLink":"ncbi.nlm.nih.gov/pubmed/24977967","link":"https://www.ncbi.nlm.nih.gov/pubmed/24977967","title":{"tagName":"span","source":"Smith SC, et al. (2014). Clinical endocannabinoid deficiency (CECD) revisited: Can this concept explain the therapeutic benefits of cannabis in migraine, fibromyalgia, irritable bowel syndrome and other treatment-resistant conditions?"}},{"displayLink":"3390/ijms19030833","link":"https://doi.org/10.3390%2Fijms19030833","title":{"tagName":"span","source":"Zou S, et al. (2018). Cannabinoid receptors and the endocannabinoid system: Signaling and function in the central nervous system. DOI:"}}],"byline":{"authors":[{"id":211,"name":{"display":"Crystal Raypole","first":"Crystal","last":"Raypole"},"link":"/authors/crystal-raypole","type":{"value":"author","label":"Author"},"nid":"","specialties":[],"guestTitle":"","bio":{"text":"\u003cp\u003eCrystal Raypole\u0026#8217;s work appears on Healthline, and she\u0026#8217;s previously worked as a writer and editor for GoodTherapy. Her interests include Japanese language and translation, cooking, natural sciences, sex positivity, and mental health. In particular, she’s committed to helping decrease stigma around mental health issues. She hopes to someday write fiction — if she can stop reading fiction long enough to write more than a few chapters of anything.\u003c/p\u003e\n"},"avatar":{"title":"","width":200,"height":200,"src":"https://post.healthline.com/wp-content/uploads/2020/01/200x200_Crystal_Raypole.png"}}],"medicalReviewers":[{"id":115,"name":{"display":"Alan Carter, Pharm.D.","first":"Alan","last":"Carter, PharmD"},"userLogin":"achealthline","links":{"website":"","facebook":"","linkedin":"https://www.linkedin.com/in/alancarterpharmd/","twitter":"","instagram":"","tiktok":""},"link":"/reviewers/alan-carter-pharmd","type":{"value":"medical_reviewer","label":"Medical Advisor"},"nid":"122506","specialties":[],"guestTitle":"","bio":{"text":"\u003cp style=\"text-align: left;\"\u003e\u003cem\u003eThis individual is no longer a medical reviewer in our network. The credentials and contact information reflected here may not be current.\u003c/em\u003e\u003c/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eDr. Alan Carter is a clinical pharmacist with interests in medical research, pharmacy practice, and medication formulary management. He is an independent contracted medical director for pharmaceutical development, clinical pharmacy specialist, and adjunct clinical assistant professor of pharmacy.\u003c/span\u003e\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eEducation\u003c/strong\u003e\u003c/p\u003e\n\u003cul\u003e\n\u003cli style=\"font-weight: 400;\" aria-level=\"1\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eUniversity of Missouri \u0026#8211; Kansas City, BS, PharmD\u003c/span\u003e\u003c/li\u003e\n\u003c/ul\u003e\n\u003cp\u003e\u003cstrong\u003eCertifications\u003c/strong\u003e\u003c/p\u003e\n\u003cul\u003e\n\u003cli aria-level=\"1\"\u003eLicensed Pharmacist\u003c/li\u003e\n\u003cli style=\"font-weight: 400;\" aria-level=\"1\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eKansas Board of Pharmacy\u003c/span\u003e\u003c/li\u003e\n\u003cli style=\"font-weight: 400;\" aria-level=\"1\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eMissouri Board of Pharmacy\u003c/span\u003e\u003c/li\u003e\n\u003cli style=\"font-weight: 400;\" aria-level=\"1\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eCertified Immunizing Pharmacist\u003c/span\u003e\u003c/li\u003e\n\u003cli style=\"font-weight: 400;\" aria-level=\"1\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eCertified Smoking Cessation Specialist\u003c/span\u003e\u003c/li\u003e\n\u003c/ul\u003e\n\u003cp\u003e\u003cstrong\u003eProfessional Accomplishments\u003c/strong\u003e\u003c/p\u003e\n\u003cul\u003e\n\u003cli style=\"font-weight: 400;\" aria-level=\"1\"\u003e\u003cspan style=\"font-weight: 400;\"\u003ePublished 20 journal articles to date, performs medical journal peer review, and serves on many professional committees and boards\u003c/span\u003e\u003c/li\u003e\n\u003cli style=\"font-weight: 400;\" aria-level=\"1\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eAwarded the Pharmacy Career Achievement Award by the University of Missouri \u0026#8211; Kansas City, 2019\u003c/span\u003e\u003c/li\u003e\n\u003cli style=\"font-weight: 400;\" aria-level=\"1\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eServed as principal investigator for the National Institutes of Health, NINDS BRAIN Initiative for Neurological Drug Development, 2015-2018\u003c/span\u003e\u003c/li\u003e\n\u003c/ul\u003e\n\u003cp\u003e\u003cstrong\u003eAffiliations\u003c/strong\u003e\u003c/p\u003e\n\u003cul\u003e\n\u003cli style=\"font-weight: 400;\" aria-level=\"1\"\u003e\u003ca href=\"https://pharmacy.umkc.edu/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eUniversity of Missouri-Kansas City School of Pharmacy\u003c/span\u003e\u003c/a\u003e\u003c/li\u003e\n\u003cli style=\"font-weight: 400;\" aria-level=\"1\"\u003e\u003ca href=\"https://www.philambdasigma.org/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003ePhi Lambda Sigma Pharmacy Leadership Society\u003c/span\u003e\u003c/a\u003e\u003c/li\u003e\n\u003c/ul\u003e\n"},"avatar":{"title":"","width":500,"height":500,"src":"https://post.healthline.com/wp-content/uploads/2022/01/Alan-Carter-500x500-Bio.png"}}],"id":"wp-96687","updateReason":[],"editor":"Judy Lee","factCheckedBy":"","factCheckers":[],"articleHistory":{"2019-05-17":{"updateReason":[],"authors":"Crystal Raypole","editor":"Judy Lee","medicallyReviewedBy":"Alan Carter, PharmD"}},"articleDates":{"factChecked":{"date":null,"display":""},"medicallyReviewed":{"date":1558101793,"display":"May 17, 2019"},"published":{"date":1558101793,"display":"May 17, 2019"},"lastUpdates":{"date":1558101793,"display":"May 17, 2019"},"modified":{"date":1712068789,"display":"April 2, 2024"}},"type":"healthfeature","language":"en"},"isCorp":false,"isReference":false,"isPremiumVideo":false,"isStandaloneVideo":false,"isStandaloneRecipe":false,"schemaObj":{"@context":"https://schema.org","publisher":{"@type":"Organization","name":"Healthline Media","logo":{"@type":"ImageObject","url":"https://media.post.rvohealth.io/wp-content/uploads/2023/09/Healthline-Black-Logo.png"}},"@type":"MedicalWebPage","headline":"A Simple Guide to the Endocannabinoid System","description":"The endocannabinoid is a complex system that still isn't fully understood. We'll go over what experts do know about it, including how it works, the ways it interacts with cannabis, and theories about its role in different conditions.","keywords":"endocannabinoid system","author":{"@type":"Person","name":"Crystal Raypole"},"lastReviewed":"2019-05-17T14:03:13Z","url":"https://www.healthline.com/health/endocannabinoid-system","datePublished":"2019-05-17T14:03:13Z","dateModified":"2019-05-17T14:03:13Z","articleSection":"Uncategorized","correction":{"@type":"CorrectionComment","text":"","datePublished":"2019-05-17"},"reviewedBy":"Alan Carter, Pharm.D.","thumbnail":["https://media.post.rvohealth.io/wp-content/uploads/2019/04/Doctor_Talk_Female_Laptop-732x549-Thumbnail.jpg"]},"hero":{}}},"ampLibs":{},"scrollArticles":[{"title":["The Definitive Guide to Yoga"],"text":["Whether you're a beginner or advanced yogi, here's our thorough guide to achieving a successful practice. Get expert advice, meditation tips, and more."],"link":"/health/fitness-exercise/definitive-guide-to-yoga","imageAlt":"The Definitive Guide to Yoga","thumbnail":"https://media.post.rvohealth.io/wp-content/uploads/2020/08/Yoga_Tablet_Home_Female-732x549-Thumbnail-732x549.jpg","medicallyReviewedBy":{"reviewerName":"Daniel Bubnis, M.S., NASM-CPT, NASE Level II-CSS","reviewerImage":{"path":"https://media.post.rvohealth.io/wp-content/uploads/2022/01/Daniel-Bubnis-500x500-Bio.png","width":200,"height":200,"altText":""},"specialties":["fitness"]},"isNutrition":false,"authors":[{"id":3711,"name":{"display":"Tiffany Cruikshank from Yoga Medicine","first":"tiffany","last":"cruikshank"},"userLogin":"tcruikshank","links":{"website":"","facebook":"","linkedin":"","twitter":"","instagram":"","tiktok":""},"type":{"value":"","label":""},"specialties":[],"bio":{},"avatar":{"title":"","src":""}}],"reviewedByHeader":"Medically reviewed by"},{"title":["Cannabis Got You Paranoid? How to Deal With It"],"text":["Paranoia is one of the less desirable effects that marijuana has on some people. Learn why it happens, who's more likely to experience it, and how to…"],"link":"/health/marijuana-paranoia","imageAlt":"Cannabis Got You Paranoid? How to Deal With It","thumbnail":"https://media.post.rvohealth.io/wp-content/uploads/2020/01/woman-home-eyes-closed-headphones-relaxing-732x549-thumbnail-732x549.jpg","medicallyReviewedBy":{"reviewerName":"Debra Sullivan, Ph.D., MSN, R.N., CNE, COI","reviewerImage":{"path":"https://media.post.rvohealth.io/wp-content/uploads/2022/01/Debra-Sullivan-500x500-Bio.png","width":200,"height":200,"altText":""}},"isNutrition":false,"authors":[{"id":211,"name":{"display":"Crystal Raypole","first":"Crystal","last":"Raypole"},"userLogin":"raypolecrystal","links":{"website":"","facebook":"","linkedin":"","twitter":"","instagram":"","tiktok":""},"link":"/authors/crystal-raypole","type":{"value":"author","label":"Author"},"nid":"","specialties":[],"guestTitle":"","bio":{"text":"\u003cp\u003eCrystal Raypole\u0026#8217;s work appears on Healthline, and she\u0026#8217;s previously worked as a writer and editor for GoodTherapy. Her interests include Japanese language and translation, cooking, natural sciences, sex positivity, and mental health. In particular, she’s committed to helping decrease stigma around mental health issues. She hopes to someday write fiction — if she can stop reading fiction long enough to write more than a few chapters of anything.\u003c/p\u003e\n"},"avatar":{"title":"","width":200,"height":200,"src":"https://post.healthline.com/wp-content/uploads/2020/01/200x200_Crystal_Raypole.png"}}],"reviewedByHeader":"Medically reviewed by"},{"title":["A Quick Take on Cannabis and Its Effects"],"text":["As weed becomes legal in more areas, names for it are evolving. Today, more and more people are using the term cannabis to refer to weed. Read on to…"],"link":"/health/what-is-cannabis","imageAlt":"A Quick Take on Cannabis and Its Effects","thumbnail":"https://media.post.rvohealth.io/wp-content/uploads/2020/07/10269-What_Is_Cannabis-_Facts_About_Its_Components_Effects_and_Hazards_732x549-thumbnail-732x549.jpg","medicallyReviewedBy":{"reviewerName":"Femi Aremu, PharmD","reviewerImage":{"path":"https://media.post.rvohealth.io/wp-content/uploads/2022/01/Femi-Aremu-500x500-Bio.png","width":200,"height":200,"altText":""},"specialties":[]},"isNutrition":false,"authors":[{"id":49,"name":{"display":"Kimberly Holland","first":"Kimberly","last":"Holland"},"userLogin":"kimholland","links":{"website":"","facebook":"","linkedin":"","twitter":"","instagram":"https://www.instagram.com/khollandcooks/?hl=en","tiktok":""},"link":"/authors/kimberly-holland","type":{"value":"author","label":"Author"},"nid":"159200","specialties":[],"guestTitle":"","bio":{"text":"\u003cp\u003eKimberly is a freelance health, travel, and lifestyle writer and editor living in Birmingham, AL. She has previously written for Cooking Light, Eating Well, Coastal Living, Real Simple, Reader\u0026#8217;s Digest, and more. When she\u0026#8217;s not writing, you\u0026#8217;ll likely find her watching “Murder, She Wrote” and sorting her collection of books that she\u0026#8217;ll certainly one day find time to read, or planning her next vacation, preferably to an island, please.\u003c/p\u003e\n"},"avatar":{"title":"","width":200,"height":200,"src":"https://post.healthline.com/wp-content/uploads/2019/03/200x200_Kimberly_Holland.png"}}],"reviewedByHeader":"Medically reviewed by"},{"title":["Cannabis Withdrawal: What it is and What to Expect"],"text":["It is possible to have cannabis use disorder, and when you stop using it, you can have withdrawal. Learn more. "],"link":"/health/video/marijuana-withdrawal","imageAlt":"Cannabis Withdrawal: What it is and What to Expect","thumbnail":"https://media.post.rvohealth.io/wp-content/uploads/2020/09/2574-Young_man_smoking_Marijuana-732x549-thumbnail-732x549.jpg","medicallyReviewedBy":{"reviewerName":"the Healthline Medical Network","reviewerImage":{"path":"","width":0,"height":0,"altText":false}},"isNutrition":false,"authors":[{"id":6628,"name":{"display":"the Healthline Video Team","first":"the Healthline Video Team","last":""},"userLogin":"hlvideoteam","links":{"website":"","facebook":"","linkedin":"","twitter":"","instagram":"","tiktok":""},"type":{"value":"author","label":"Author"},"nid":"","specialties":[],"guestTitle":"","bio":{"text":""},"avatar":{"title":"","src":""}}],"reviewedByHeader":"Medically reviewed by"},{"title":["As Legal Cannabis Expands, More Kids Are Getting Sick From Edibles"],"text":["U.S. poison control centers recorded more than 7,000 cases of children 6 and under who consumed cannabis edibles from 2017 to 2021, according to a new…"],"link":"/health-news/more-kids-getting-sick-from-edibles-as-legal-cannabis-expands","imageAlt":"As Legal Cannabis Expands, More Kids Are Getting Sick From Edibles","thumbnail":"https://media.post.rvohealth.io/wp-content/uploads/2023/01/child-hand-brownie-732x549-thumbnail-732x549.jpg","isNutrition":false,"authors":[{"id":26,"name":{"display":"Shawn Radcliffe","first":"Shawn","last":"Radcliffe"},"userLogin":"sradcliffe","links":{"website":"","facebook":"","linkedin":"","twitter":"ShawnRadcliffe","instagram":"","tiktok":""},"link":"/authors/shawn-radcliffe","type":{"value":"author","label":"Author"},"nid":"","specialties":[],"guestTitle":"","bio":{"text":"\u003cp\u003e\u003cspan data-sheets-value=\"{\u0026quot;1\u0026quot;:2,\u0026quot;2\u0026quot;:\u0026quot;Shawn Radcliffe is a science writer and yoga teacher in Ontario, Canada. His work has appeared in print and digital publications, including Healthline, Mindbodygreen, Science \u0026amp; Nonduality, and others. Originally from New Hampshire, Shawn lived in Philadelphia and Portland, Oregon, before trading in the big city for small-town living. When he’s not reading or writing, Shawn is often backpacking, bicycling, or wandering the streets of a new city. Connect with him on Twitter.\u0026quot;}\" data-sheets-userformat=\"{\u0026quot;2\u0026quot;:771,\u0026quot;3\u0026quot;:{\u0026quot;1\u0026quot;:0},\u0026quot;4\u0026quot;:[null,2,11982760],\u0026quot;11\u0026quot;:3,\u0026quot;12\u0026quot;:0}\"\u003eShawn Radcliffe is a science writer and yoga teacher in Ontario, Canada. His work has appeared in print and digital publications, including Healthline, Mindbodygreen, Science \u0026amp; Nonduality, and others. Originally from New Hampshire, Shawn lived in Philadelphia and Portland, Oregon, before trading in the big city for small-town living. When he’s not reading or writing, Shawn is often backpacking, bicycling, or wandering the streets of a new city. Connect with him on \u003ca href=\"https://twitter.com/ShawnRadcliffe\"\u003eTwitter\u003c/a\u003e.\u003c/span\u003e\u003c/p\u003e\n"},"avatar":{"title":"","width":500,"height":500,"src":"https://post.healthline.com/wp-content/uploads/2020/08/500x500_Shawn_Radcliffe.png"}}],"reviewedByHeader":"Medically reviewed by"},{"title":["Can You Use Weed While You’re Taking Antibiotics?"],"text":["The current research isn't certain whether it could have harmful or beneficial effects. Let's look at what you need to know if you plan on using…"],"link":"/health/antibiotics/antibiotics-and-weed","imageAlt":"Can You Use Weed While You’re Taking Antibiotics?","thumbnail":"https://media.post.rvohealth.io/wp-content/uploads/2022/10/senior_rolling_marijuana_joint-732x549-thumbnail-732x549.jpg","medicallyReviewedBy":{"reviewerName":"Alan Carter, Pharm.D.","reviewerImage":{"path":"https://media.post.rvohealth.io/wp-content/uploads/2022/01/Alan-Carter-500x500-Bio.png","width":200,"height":200,"altText":""}},"isNutrition":false,"authors":[{"id":1554,"name":{"display":"S. Srakocic","first":"S.","last":"Srakocic"},"userLogin":"sbehring","links":{"website":"http://www.srakocicwriting.com/","facebook":"","linkedin":"","twitter":"","instagram":"","tiktok":""},"link":"/authors/s-srakocic","type":{"value":"author","label":"Author"},"nid":"","specialties":[],"guestTitle":"","bio":{"text":"\u003cp\u003eS. Srakocic spent several years working in healthcare before making a major change and shifting to freelance writing. Focusing her writing career on healthcare and education allows her to translate her previous experience and create articles that are both accessible and informative. Her work has appeared in a growing list of publications of all sizes. You can find out more on her \u003ca class=\"PrimaryLink BaseLink\" href=\"http://www.srakocicwriting.com/\" target=\"_blank\" rel=\"noreferrer noopener\"\u003ewebsite\u003c/a\u003e.\u003c/p\u003e\n"},"avatar":{"title":"","width":500,"height":500,"src":"https://post.healthline.com/wp-content/uploads/2021/12/Stephanie-Behring-500x500-Bio.png"}}],"reviewedByHeader":"Medically reviewed by"},{"title":["Cannabis for Chronic Pain Linked to Slightly Increased Risk of Arrhythmia"],"text":["People who use medical cannabis products for chronic pain may have a higher risk of heart rhythm disorders, or arrhythmias, according to preliminary…"],"link":"/health-news/cannabis-for-chronic-pain-linked-to-slightly-increased-risk-of-arrhythmia","imageAlt":"Cannabis for Chronic Pain Linked to Slightly Increased Risk of Arrhythmia","thumbnail":"https://media.post.rvohealth.io/wp-content/uploads/2022/08/cannabis-dispensary-732x549-thumbnail-732x549.jpg","isNutrition":false,"authors":[{"id":26,"name":{"display":"Shawn Radcliffe","first":"Shawn","last":"Radcliffe"},"userLogin":"sradcliffe","links":{"website":"","facebook":"","linkedin":"","twitter":"ShawnRadcliffe","instagram":"","tiktok":""},"link":"/authors/shawn-radcliffe","type":{"value":"author","label":"Author"},"nid":"","specialties":[],"guestTitle":"","bio":{"text":"\u003cp\u003e\u003cspan data-sheets-value=\"{\u0026quot;1\u0026quot;:2,\u0026quot;2\u0026quot;:\u0026quot;Shawn Radcliffe is a science writer and yoga teacher in Ontario, Canada. His work has appeared in print and digital publications, including Healthline, Mindbodygreen, Science \u0026amp; Nonduality, and others. Originally from New Hampshire, Shawn lived in Philadelphia and Portland, Oregon, before trading in the big city for small-town living. When he’s not reading or writing, Shawn is often backpacking, bicycling, or wandering the streets of a new city. Connect with him on Twitter.\u0026quot;}\" data-sheets-userformat=\"{\u0026quot;2\u0026quot;:771,\u0026quot;3\u0026quot;:{\u0026quot;1\u0026quot;:0},\u0026quot;4\u0026quot;:[null,2,11982760],\u0026quot;11\u0026quot;:3,\u0026quot;12\u0026quot;:0}\"\u003eShawn Radcliffe is a science writer and yoga teacher in Ontario, Canada. His work has appeared in print and digital publications, including Healthline, Mindbodygreen, Science \u0026amp; Nonduality, and others. Originally from New Hampshire, Shawn lived in Philadelphia and Portland, Oregon, before trading in the big city for small-town living. When he’s not reading or writing, Shawn is often backpacking, bicycling, or wandering the streets of a new city. Connect with him on \u003ca href=\"https://twitter.com/ShawnRadcliffe\"\u003eTwitter\u003c/a\u003e.\u003c/span\u003e\u003c/p\u003e\n"},"avatar":{"title":"","width":500,"height":500,"src":"https://post.healthline.com/wp-content/uploads/2020/08/500x500_Shawn_Radcliffe.png"}}],"reviewedByHeader":"Medically reviewed by"},{"title":["States With Legalized Cannabis Have Fewer Synthetic Cannabinoid Poisonings"],"text":["New research shows a drop in synthetic cannabis poisonings in states that have legalized recreational cannabis. Synthetic cannabis products contain…"],"link":"/health-news/states-with-legalized-cannabis-have-fewer-synthetic-cannabinoid-poisonings","imageAlt":"States With Legalized Cannabis Have Fewer Synthetic Cannabinoid Poisonings","thumbnail":"https://media.post.rvohealth.io/wp-content/uploads/2022/08/cannabis-shop-oregon-732x549-thumbnail-732x549.jpg","isNutrition":false,"authors":[{"id":26,"name":{"display":"Shawn Radcliffe","first":"Shawn","last":"Radcliffe"},"userLogin":"sradcliffe","links":{"website":"","facebook":"","linkedin":"","twitter":"ShawnRadcliffe","instagram":"","tiktok":""},"link":"/authors/shawn-radcliffe","type":{"value":"author","label":"Author"},"nid":"","specialties":[],"guestTitle":"","bio":{"text":"\u003cp\u003e\u003cspan data-sheets-value=\"{\u0026quot;1\u0026quot;:2,\u0026quot;2\u0026quot;:\u0026quot;Shawn Radcliffe is a science writer and yoga teacher in Ontario, Canada. His work has appeared in print and digital publications, including Healthline, Mindbodygreen, Science \u0026amp; Nonduality, and others. Originally from New Hampshire, Shawn lived in Philadelphia and Portland, Oregon, before trading in the big city for small-town living. When he’s not reading or writing, Shawn is often backpacking, bicycling, or wandering the streets of a new city. Connect with him on Twitter.\u0026quot;}\" data-sheets-userformat=\"{\u0026quot;2\u0026quot;:771,\u0026quot;3\u0026quot;:{\u0026quot;1\u0026quot;:0},\u0026quot;4\u0026quot;:[null,2,11982760],\u0026quot;11\u0026quot;:3,\u0026quot;12\u0026quot;:0}\"\u003eShawn Radcliffe is a science writer and yoga teacher in Ontario, Canada. His work has appeared in print and digital publications, including Healthline, Mindbodygreen, Science \u0026amp; Nonduality, and others. Originally from New Hampshire, Shawn lived in Philadelphia and Portland, Oregon, before trading in the big city for small-town living. When he’s not reading or writing, Shawn is often backpacking, bicycling, or wandering the streets of a new city. Connect with him on \u003ca href=\"https://twitter.com/ShawnRadcliffe\"\u003eTwitter\u003c/a\u003e.\u003c/span\u003e\u003c/p\u003e\n"},"avatar":{"title":"","width":500,"height":500,"src":"https://post.healthline.com/wp-content/uploads/2020/08/500x500_Shawn_Radcliffe.png"}}],"reviewedByHeader":"Medically reviewed by"}]},"pathname":"/infinite","query":{"isControl":false,"url":"/health/endocannabinoid-system","enableDatadogRUM":false,"scrollIndicator":false,"prerollAdRule":false,"postrollAdRule":false,"activationReadNext":true,"adbDlbFix":false,"livedExperienceMVP":false,"expandedTableOfContents":false,"collapsedTableOfContents":false,"experimentalRPM":"variant","adbridgFlag":false,"jwPlayerFix":true,"dcsCopayBestOffer":"control","dcsNativeCoupon":"control","dcsCopayOnly":"variant","reducedFontSize":false,"moveImageGalleryBelowH2":false,"affiliateDisclaimer":false,"affiliateDisclaimer2":false,"adBlockerDetection":false,"contentClusterInfiniteScroll":false,"oneTrustCPRA":true,"pathingTest":true,"moveImageGalleryBelowDeck":"control","apscustomRemoval":false,"showClusterNavMenu":true,"showReferenceJumpLink":"control","showNonCostJumpLink":"control","traveler":"variant"},"publicPath":"https://assets.healthline.com/_next/","appState":{"title":"Endocannabinoid System: A Simple Guide to How It Works","canonical":"https://www.healthline.com/health/endocannabinoid-system","hrlContentId":"wp-96687","isArticle":true,"isContentSeries":false,"canonicalPath":"/health/endocannabinoid-system","pageTemplate":"Tabbed Article","logMoreMetrics":true,"adsSponsored":false,"isCPUV":false,"newsletter":{"tags":"","categories":"uncategorized"},"isSponsoredArticle":false,"targeting":{"k1":"marijuanause","k2":"substanceuse","k3":"health","kmeta":"eczema-predictive-aq,nsclc-predictive-aq,obesity-predictive-aq,bipolar-predictive-aq-1,bipolar-predictive-aq,vraylar24bp","msiteactive":"false","url":"/health/endocannabinoid-system","articleId":"wp-96687","adLayout":"MEDIUM_DRIVER"},"categories":[{"name":"Uncategorized","slug":"uncategorized","link":"/uncategorized","children":[]}],"subcategories":[],"sponsoredNavMenu":false,"author":"Crystal Raypole","editor":"Judy Lee","contentForm":"Non-Head Term","type":"healthfeature","vertical":"VMS","trackingTerms":[],"isPremiumVideo":false,"isStandaloneVideo":false,"isStandaloneRecipe":false,"isNewsArticle":false,"hasEmbeddedJWPlayer":false,"pageHasDasPreroll":true,"byline":{"authors":[{"id":211,"name":{"display":"Crystal Raypole","first":"Crystal","last":"Raypole"},"link":"/authors/crystal-raypole","type":{"value":"author","label":"Author"},"nid":"","specialties":[],"guestTitle":"","bio":{"text":"\u003cp\u003eCrystal Raypole\u0026#8217;s work appears on Healthline, and she\u0026#8217;s previously worked as a writer and editor for GoodTherapy. Her interests include Japanese language and translation, cooking, natural sciences, sex positivity, and mental health. In particular, she’s committed to helping decrease stigma around mental health issues. She hopes to someday write fiction — if she can stop reading fiction long enough to write more than a few chapters of anything.\u003c/p\u003e\n"},"avatar":{"title":"","width":200,"height":200,"src":"https://post.healthline.com/wp-content/uploads/2020/01/200x200_Crystal_Raypole.png"}}],"medicalReviewers":[{"id":115,"name":{"display":"Alan Carter, Pharm.D.","first":"Alan","last":"Carter, PharmD"},"userLogin":"achealthline","links":{"website":"","facebook":"","linkedin":"https://www.linkedin.com/in/alancarterpharmd/","twitter":"","instagram":"","tiktok":""},"link":"/reviewers/alan-carter-pharmd","type":{"value":"medical_reviewer","label":"Medical Advisor"},"nid":"122506","specialties":[],"guestTitle":"","bio":{"text":"\u003cp style=\"text-align: left;\"\u003e\u003cem\u003eThis individual is no longer a medical reviewer in our network. The credentials and contact information reflected here may not be current.\u003c/em\u003e\u003c/p\u003e\n\u003cp\u003e\u003cspan style=\"font-weight: 400;\"\u003eDr. Alan Carter is a clinical pharmacist with interests in medical research, pharmacy practice, and medication formulary management. He is an independent contracted medical director for pharmaceutical development, clinical pharmacy specialist, and adjunct clinical assistant professor of pharmacy.\u003c/span\u003e\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eEducation\u003c/strong\u003e\u003c/p\u003e\n\u003cul\u003e\n\u003cli style=\"font-weight: 400;\" aria-level=\"1\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eUniversity of Missouri \u0026#8211; Kansas City, BS, PharmD\u003c/span\u003e\u003c/li\u003e\n\u003c/ul\u003e\n\u003cp\u003e\u003cstrong\u003eCertifications\u003c/strong\u003e\u003c/p\u003e\n\u003cul\u003e\n\u003cli aria-level=\"1\"\u003eLicensed Pharmacist\u003c/li\u003e\n\u003cli style=\"font-weight: 400;\" aria-level=\"1\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eKansas Board of Pharmacy\u003c/span\u003e\u003c/li\u003e\n\u003cli style=\"font-weight: 400;\" aria-level=\"1\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eMissouri Board of Pharmacy\u003c/span\u003e\u003c/li\u003e\n\u003cli style=\"font-weight: 400;\" aria-level=\"1\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eCertified Immunizing Pharmacist\u003c/span\u003e\u003c/li\u003e\n\u003cli style=\"font-weight: 400;\" aria-level=\"1\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eCertified Smoking Cessation Specialist\u003c/span\u003e\u003c/li\u003e\n\u003c/ul\u003e\n\u003cp\u003e\u003cstrong\u003eProfessional Accomplishments\u003c/strong\u003e\u003c/p\u003e\n\u003cul\u003e\n\u003cli style=\"font-weight: 400;\" aria-level=\"1\"\u003e\u003cspan style=\"font-weight: 400;\"\u003ePublished 20 journal articles to date, performs medical journal peer review, and serves on many professional committees and boards\u003c/span\u003e\u003c/li\u003e\n\u003cli style=\"font-weight: 400;\" aria-level=\"1\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eAwarded the Pharmacy Career Achievement Award by the University of Missouri \u0026#8211; Kansas City, 2019\u003c/span\u003e\u003c/li\u003e\n\u003cli style=\"font-weight: 400;\" aria-level=\"1\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eServed as principal investigator for the National Institutes of Health, NINDS BRAIN Initiative for Neurological Drug Development, 2015-2018\u003c/span\u003e\u003c/li\u003e\n\u003c/ul\u003e\n\u003cp\u003e\u003cstrong\u003eAffiliations\u003c/strong\u003e\u003c/p\u003e\n\u003cul\u003e\n\u003cli style=\"font-weight: 400;\" aria-level=\"1\"\u003e\u003ca href=\"https://pharmacy.umkc.edu/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003eUniversity of Missouri-Kansas City School of Pharmacy\u003c/span\u003e\u003c/a\u003e\u003c/li\u003e\n\u003cli style=\"font-weight: 400;\" aria-level=\"1\"\u003e\u003ca href=\"https://www.philambdasigma.org/\"\u003e\u003cspan style=\"font-weight: 400;\"\u003ePhi Lambda Sigma Pharmacy Leadership Society\u003c/span\u003e\u003c/a\u003e\u003c/li\u003e\n\u003c/ul\u003e\n"},"avatar":{"title":"","width":500,"height":500,"src":"https://post.healthline.com/wp-content/uploads/2022/01/Alan-Carter-500x500-Bio.png"}}],"id":"wp-96687","updateReason":[],"editor":"Judy Lee","factCheckedBy":"","factCheckers":[],"articleHistory":{"2019-05-17":{"updateReason":[],"authors":"Crystal Raypole","editor":"Judy Lee","medicallyReviewedBy":"Alan Carter, PharmD"}},"articleDates":{"factChecked":{"date":null,"display":""},"medicallyReviewed":{"date":1558101793,"display":"May 17, 2019"},"published":{"date":1558101793,"display":"May 17, 2019"},"lastUpdates":{"date":1558101793,"display":"May 17, 2019"},"modified":{"date":1712068789,"display":"April 2, 2024"}},"type":"healthfeature","language":"en"},"cesData":{"metaDescription":"The endocannabinoid is a complex system that still isn't fully understood. We'll go over what experts do know about it, including how it works, the ways it interacts with cannabis, and theories about its role in different conditions.","title":"Endocannabinoid System: A Simple Guide to How It Works","iab_tag_tier_1":[],"iab_tag_tier_2":[],"mpdTags":[{"confidence":0.9860379591745897,"type":"topic_level_1","value":"health"},{"confidence":0.6421368658185361,"type":"topic_level_2","value":"neurology"},{"confidence":0.8551967451922423,"type":"topic_level_3","value":"cannabis"},{"confidence":0.12152074876798367,"type":"topic_level_4","value":"cbd"},{"confidence":0.7030395102905068,"type":"entity","value":"ec"}]},"relatedStories":false,"wellness":{"title":"wellness reads","coverImageUrl":"/hlcmsresource/images/frontend-static/sidebar-wellness/7354-wellness_reads_option2_600x260-rightrail.jpg","items":[{"title":{"text":"10 Exercises to Tone Every Inch of Your Body","matches":"Tone Every Inch"},"url":"/health/fitness-exercise/10-best-exercises-everyday","thumbnail":"https://media.post.rvohealth.io/wp-content/uploads/2020/07/7040-hispanic_female_exercise-732x549-thumbnail-732x549.jpg"},{"title":{"text":"For a Longer Life and Happier Gut, Eat More Fiber","matches":"Longer Life"},"url":"/health/food-nutrition/fiber-diet-good-for-gut-and-health","thumbnail":"https://media.post.rvohealth.io/wp-content/uploads/2018/01/oatmeal-granola-berries-fiber-732x549-thumbnail-732x549.jpg"},{"title":{"text":"What You Need to Know About the Health Benefits of Collagen","matches":"Collagen"},"url":"/nutrition/collagen-benefits","thumbnail":"https://media.post.rvohealth.io/wp-content/uploads/2020/02/mirror-beauty-skin-732x549-thumbnail-732x549.jpg"},{"title":{"text":"6 Ways to Boost Your Coffee with Vitamins and Antioxidants","matches":"Boost Your Coffee"},"url":"/health/food-nutrition/vitamin-coffee-natural-boost","thumbnail":"https://media.post.rvohealth.io/wp-content/uploads/2020/08/Hands_Coffee_Cinnamon_732x549-thumbnail-732x549.jpg"},{"title":{"text":"The 3-Day Fix for Energy","matches":"3-Day Fix"},"url":"/health/healthy-sleep/guide-fix-fatigue-and-sleepiness","thumbnail":"https://media.post.rvohealth.io/wp-content/uploads/2018/03/male-walking-outdoors-poc-happy-732x549-thumbnail-732x549.jpg"}]},"shouldLoadSEOClarity":false,"shouldLoadFullStory":false,"infiniteScroll":true,"infScrollArticles":[{"title":["The Definitive Guide to Yoga"],"text":["Whether you're a beginner or advanced yogi, here's our thorough guide to achieving a successful practice. Get expert advice, meditation tips, and more."],"link":"/health/fitness-exercise/definitive-guide-to-yoga","imageAlt":"The Definitive Guide to Yoga","thumbnail":"https://media.post.rvohealth.io/wp-content/uploads/2020/08/Yoga_Tablet_Home_Female-732x549-Thumbnail-732x549.jpg","medicallyReviewedBy":{"reviewerName":"Daniel Bubnis, M.S., NASM-CPT, NASE Level II-CSS","reviewerImage":{"path":"https://media.post.rvohealth.io/wp-content/uploads/2022/01/Daniel-Bubnis-500x500-Bio.png","width":200,"height":200,"altText":""},"specialties":["fitness"]},"isNutrition":false,"authors":[{"id":3711,"name":{"display":"Tiffany Cruikshank from Yoga Medicine","first":"tiffany","last":"cruikshank"},"userLogin":"tcruikshank","links":{"website":"","facebook":"","linkedin":"","twitter":"","instagram":"","tiktok":""},"type":{"value":"","label":""},"specialties":[],"bio":{},"avatar":{"title":"","src":""}}],"reviewedByHeader":"Medically reviewed by"},{"title":["Cannabis Got You Paranoid? How to Deal With It"],"text":["Paranoia is one of the less desirable effects that marijuana has on some people. Learn why it happens, who's more likely to experience it, and how to…"],"link":"/health/marijuana-paranoia","imageAlt":"Cannabis Got You Paranoid? How to Deal With It","thumbnail":"https://media.post.rvohealth.io/wp-content/uploads/2020/01/woman-home-eyes-closed-headphones-relaxing-732x549-thumbnail-732x549.jpg","medicallyReviewedBy":{"reviewerName":"Debra Sullivan, Ph.D., MSN, R.N., CNE, COI","reviewerImage":{"path":"https://media.post.rvohealth.io/wp-content/uploads/2022/01/Debra-Sullivan-500x500-Bio.png","width":200,"height":200,"altText":""}},"isNutrition":false,"authors":[{"id":211,"name":{"display":"Crystal Raypole","first":"Crystal","last":"Raypole"},"userLogin":"raypolecrystal","links":{"website":"","facebook":"","linkedin":"","twitter":"","instagram":"","tiktok":""},"link":"/authors/crystal-raypole","type":{"value":"author","label":"Author"},"nid":"","specialties":[],"guestTitle":"","bio":{"text":"\u003cp\u003eCrystal Raypole\u0026#8217;s work appears on Healthline, and she\u0026#8217;s previously worked as a writer and editor for GoodTherapy. Her interests include Japanese language and translation, cooking, natural sciences, sex positivity, and mental health. In particular, she’s committed to helping decrease stigma around mental health issues. She hopes to someday write fiction — if she can stop reading fiction long enough to write more than a few chapters of anything.\u003c/p\u003e\n"},"avatar":{"title":"","width":200,"height":200,"src":"https://post.healthline.com/wp-content/uploads/2020/01/200x200_Crystal_Raypole.png"}}],"reviewedByHeader":"Medically reviewed by"},{"title":["A Quick Take on Cannabis and Its Effects"],"text":["As weed becomes legal in more areas, names for it are evolving. Today, more and more people are using the term cannabis to refer to weed. Read on to…"],"link":"/health/what-is-cannabis","imageAlt":"A Quick Take on Cannabis and Its Effects","thumbnail":"https://media.post.rvohealth.io/wp-content/uploads/2020/07/10269-What_Is_Cannabis-_Facts_About_Its_Components_Effects_and_Hazards_732x549-thumbnail-732x549.jpg","medicallyReviewedBy":{"reviewerName":"Femi Aremu, PharmD","reviewerImage":{"path":"https://media.post.rvohealth.io/wp-content/uploads/2022/01/Femi-Aremu-500x500-Bio.png","width":200,"height":200,"altText":""},"specialties":[]},"isNutrition":false,"authors":[{"id":49,"name":{"display":"Kimberly Holland","first":"Kimberly","last":"Holland"},"userLogin":"kimholland","links":{"website":"","facebook":"","linkedin":"","twitter":"","instagram":"https://www.instagram.com/khollandcooks/?hl=en","tiktok":""},"link":"/authors/kimberly-holland","type":{"value":"author","label":"Author"},"nid":"159200","specialties":[],"guestTitle":"","bio":{"text":"\u003cp\u003eKimberly is a freelance health, travel, and lifestyle writer and editor living in Birmingham, AL. She has previously written for Cooking Light, Eating Well, Coastal Living, Real Simple, Reader\u0026#8217;s Digest, and more. When she\u0026#8217;s not writing, you\u0026#8217;ll likely find her watching “Murder, She Wrote” and sorting her collection of books that she\u0026#8217;ll certainly one day find time to read, or planning her next vacation, preferably to an island, please.\u003c/p\u003e\n"},"avatar":{"title":"","width":200,"height":200,"src":"https://post.healthline.com/wp-content/uploads/2019/03/200x200_Kimberly_Holland.png"}}],"reviewedByHeader":"Medically reviewed by"},{"title":["Cannabis Withdrawal: What it is and What to Expect"],"text":["It is possible to have cannabis use disorder, and when you stop using it, you can have withdrawal. Learn more. "],"link":"/health/video/marijuana-withdrawal","imageAlt":"Cannabis Withdrawal: What it is and What to Expect","thumbnail":"https://media.post.rvohealth.io/wp-content/uploads/2020/09/2574-Young_man_smoking_Marijuana-732x549-thumbnail-732x549.jpg","medicallyReviewedBy":{"reviewerName":"the Healthline Medical Network","reviewerImage":{"path":"","width":0,"height":0,"altText":false}},"isNutrition":false,"authors":[{"id":6628,"name":{"display":"the Healthline Video Team","first":"the Healthline Video Team","last":""},"userLogin":"hlvideoteam","links":{"website":"","facebook":"","linkedin":"","twitter":"","instagram":"","tiktok":""},"type":{"value":"author","label":"Author"},"nid":"","specialties":[],"guestTitle":"","bio":{"text":""},"avatar":{"title":"","src":""}}],"reviewedByHeader":"Medically reviewed by"},{"title":["As Legal Cannabis Expands, More Kids Are Getting Sick From Edibles"],"text":["U.S. poison control centers recorded more than 7,000 cases of children 6 and under who consumed cannabis edibles from 2017 to 2021, according to a new…"],"link":"/health-news/more-kids-getting-sick-from-edibles-as-legal-cannabis-expands","imageAlt":"As Legal Cannabis Expands, More Kids Are Getting Sick From Edibles","thumbnail":"https://media.post.rvohealth.io/wp-content/uploads/2023/01/child-hand-brownie-732x549-thumbnail-732x549.jpg","isNutrition":false,"authors":[{"id":26,"name":{"display":"Shawn Radcliffe","first":"Shawn","last":"Radcliffe"},"userLogin":"sradcliffe","links":{"website":"","facebook":"","linkedin":"","twitter":"ShawnRadcliffe","instagram":"","tiktok":""},"link":"/authors/shawn-radcliffe","type":{"value":"author","label":"Author"},"nid":"","specialties":[],"guestTitle":"","bio":{"text":"\u003cp\u003e\u003cspan data-sheets-value=\"{\u0026quot;1\u0026quot;:2,\u0026quot;2\u0026quot;:\u0026quot;Shawn Radcliffe is a science writer and yoga teacher in Ontario, Canada. His work has appeared in print and digital publications, including Healthline, Mindbodygreen, Science \u0026amp; Nonduality, and others. Originally from New Hampshire, Shawn lived in Philadelphia and Portland, Oregon, before trading in the big city for small-town living. When he’s not reading or writing, Shawn is often backpacking, bicycling, or wandering the streets of a new city. Connect with him on Twitter.\u0026quot;}\" data-sheets-userformat=\"{\u0026quot;2\u0026quot;:771,\u0026quot;3\u0026quot;:{\u0026quot;1\u0026quot;:0},\u0026quot;4\u0026quot;:[null,2,11982760],\u0026quot;11\u0026quot;:3,\u0026quot;12\u0026quot;:0}\"\u003eShawn Radcliffe is a science writer and yoga teacher in Ontario, Canada. His work has appeared in print and digital publications, including Healthline, Mindbodygreen, Science \u0026amp; Nonduality, and others. Originally from New Hampshire, Shawn lived in Philadelphia and Portland, Oregon, before trading in the big city for small-town living. When he’s not reading or writing, Shawn is often backpacking, bicycling, or wandering the streets of a new city. Connect with him on \u003ca href=\"https://twitter.com/ShawnRadcliffe\"\u003eTwitter\u003c/a\u003e.\u003c/span\u003e\u003c/p\u003e\n"},"avatar":{"title":"","width":500,"height":500,"src":"https://post.healthline.com/wp-content/uploads/2020/08/500x500_Shawn_Radcliffe.png"}}],"reviewedByHeader":"Medically reviewed by"},{"title":["Can You Use Weed While You’re Taking Antibiotics?"],"text":["The current research isn't certain whether it could have harmful or beneficial effects. Let's look at what you need to know if you plan on using…"],"link":"/health/antibiotics/antibiotics-and-weed","imageAlt":"Can You Use Weed While You’re Taking Antibiotics?","thumbnail":"https://media.post.rvohealth.io/wp-content/uploads/2022/10/senior_rolling_marijuana_joint-732x549-thumbnail-732x549.jpg","medicallyReviewedBy":{"reviewerName":"Alan Carter, Pharm.D.","reviewerImage":{"path":"https://media.post.rvohealth.io/wp-content/uploads/2022/01/Alan-Carter-500x500-Bio.png","width":200,"height":200,"altText":""}},"isNutrition":false,"authors":[{"id":1554,"name":{"display":"S. Srakocic","first":"S.","last":"Srakocic"},"userLogin":"sbehring","links":{"website":"http://www.srakocicwriting.com/","facebook":"","linkedin":"","twitter":"","instagram":"","tiktok":""},"link":"/authors/s-srakocic","type":{"value":"author","label":"Author"},"nid":"","specialties":[],"guestTitle":"","bio":{"text":"\u003cp\u003eS. Srakocic spent several years working in healthcare before making a major change and shifting to freelance writing. Focusing her writing career on healthcare and education allows her to translate her previous experience and create articles that are both accessible and informative. Her work has appeared in a growing list of publications of all sizes. You can find out more on her \u003ca class=\"PrimaryLink BaseLink\" href=\"http://www.srakocicwriting.com/\" target=\"_blank\" rel=\"noreferrer noopener\"\u003ewebsite\u003c/a\u003e.\u003c/p\u003e\n"},"avatar":{"title":"","width":500,"height":500,"src":"https://post.healthline.com/wp-content/uploads/2021/12/Stephanie-Behring-500x500-Bio.png"}}],"reviewedByHeader":"Medically reviewed by"},{"title":["Cannabis for Chronic Pain Linked to Slightly Increased Risk of Arrhythmia"],"text":["People who use medical cannabis products for chronic pain may have a higher risk of heart rhythm disorders, or arrhythmias, according to preliminary…"],"link":"/health-news/cannabis-for-chronic-pain-linked-to-slightly-increased-risk-of-arrhythmia","imageAlt":"Cannabis for Chronic Pain Linked to Slightly Increased Risk of Arrhythmia","thumbnail":"https://media.post.rvohealth.io/wp-content/uploads/2022/08/cannabis-dispensary-732x549-thumbnail-732x549.jpg","isNutrition":false,"authors":[{"id":26,"name":{"display":"Shawn Radcliffe","first":"Shawn","last":"Radcliffe"},"userLogin":"sradcliffe","links":{"website":"","facebook":"","linkedin":"","twitter":"ShawnRadcliffe","instagram":"","tiktok":""},"link":"/authors/shawn-radcliffe","type":{"value":"author","label":"Author"},"nid":"","specialties":[],"guestTitle":"","bio":{"text":"\u003cp\u003e\u003cspan data-sheets-value=\"{\u0026quot;1\u0026quot;:2,\u0026quot;2\u0026quot;:\u0026quot;Shawn Radcliffe is a science writer and yoga teacher in Ontario, Canada. His work has appeared in print and digital publications, including Healthline, Mindbodygreen, Science \u0026amp; Nonduality, and others. Originally from New Hampshire, Shawn lived in Philadelphia and Portland, Oregon, before trading in the big city for small-town living. When he’s not reading or writing, Shawn is often backpacking, bicycling, or wandering the streets of a new city. Connect with him on Twitter.\u0026quot;}\" data-sheets-userformat=\"{\u0026quot;2\u0026quot;:771,\u0026quot;3\u0026quot;:{\u0026quot;1\u0026quot;:0},\u0026quot;4\u0026quot;:[null,2,11982760],\u0026quot;11\u0026quot;:3,\u0026quot;12\u0026quot;:0}\"\u003eShawn Radcliffe is a science writer and yoga teacher in Ontario, Canada. His work has appeared in print and digital publications, including Healthline, Mindbodygreen, Science \u0026amp; Nonduality, and others. Originally from New Hampshire, Shawn lived in Philadelphia and Portland, Oregon, before trading in the big city for small-town living. When he’s not reading or writing, Shawn is often backpacking, bicycling, or wandering the streets of a new city. Connect with him on \u003ca href=\"https://twitter.com/ShawnRadcliffe\"\u003eTwitter\u003c/a\u003e.\u003c/span\u003e\u003c/p\u003e\n"},"avatar":{"title":"","width":500,"height":500,"src":"https://post.healthline.com/wp-content/uploads/2020/08/500x500_Shawn_Radcliffe.png"}}],"reviewedByHeader":"Medically reviewed by"},{"title":["States With Legalized Cannabis Have Fewer Synthetic Cannabinoid Poisonings"],"text":["New research shows a drop in synthetic cannabis poisonings in states that have legalized recreational cannabis. Synthetic cannabis products contain…"],"link":"/health-news/states-with-legalized-cannabis-have-fewer-synthetic-cannabinoid-poisonings","imageAlt":"States With Legalized Cannabis Have Fewer Synthetic Cannabinoid Poisonings","thumbnail":"https://media.post.rvohealth.io/wp-content/uploads/2022/08/cannabis-shop-oregon-732x549-thumbnail-732x549.jpg","isNutrition":false,"authors":[{"id":26,"name":{"display":"Shawn Radcliffe","first":"Shawn","last":"Radcliffe"},"userLogin":"sradcliffe","links":{"website":"","facebook":"","linkedin":"","twitter":"ShawnRadcliffe","instagram":"","tiktok":""},"link":"/authors/shawn-radcliffe","type":{"value":"author","label":"Author"},"nid":"","specialties":[],"guestTitle":"","bio":{"text":"\u003cp\u003e\u003cspan data-sheets-value=\"{\u0026quot;1\u0026quot;:2,\u0026quot;2\u0026quot;:\u0026quot;Shawn Radcliffe is a science writer and yoga teacher in Ontario, Canada. His work has appeared in print and digital publications, including Healthline, Mindbodygreen, Science \u0026amp; Nonduality, and others. Originally from New Hampshire, Shawn lived in Philadelphia and Portland, Oregon, before trading in the big city for small-town living. When he’s not reading or writing, Shawn is often backpacking, bicycling, or wandering the streets of a new city. Connect with him on Twitter.\u0026quot;}\" data-sheets-userformat=\"{\u0026quot;2\u0026quot;:771,\u0026quot;3\u0026quot;:{\u0026quot;1\u0026quot;:0},\u0026quot;4\u0026quot;:[null,2,11982760],\u0026quot;11\u0026quot;:3,\u0026quot;12\u0026quot;:0}\"\u003eShawn Radcliffe is a science writer and yoga teacher in Ontario, Canada. His work has appeared in print and digital publications, including Healthline, Mindbodygreen, Science \u0026amp; Nonduality, and others. Originally from New Hampshire, Shawn lived in Philadelphia and Portland, Oregon, before trading in the big city for small-town living. When he’s not reading or writing, Shawn is often backpacking, bicycling, or wandering the streets of a new city. Connect with him on \u003ca href=\"https://twitter.com/ShawnRadcliffe\"\u003eTwitter\u003c/a\u003e.\u003c/span\u003e\u003c/p\u003e\n"},"avatar":{"title":"","width":500,"height":500,"src":"https://post.healthline.com/wp-content/uploads/2020/08/500x500_Shawn_Radcliffe.png"}}],"reviewedByHeader":"Medically reviewed by"}],"hidePlacements":[],"userPreloadDrivers":{"headerNewsletter":{"_driverPath":"/health/endocannabinoid-system","_contentIndex":"page","driverId":"c54448fb-575c-413d-993f-5cf346330a9f","siteId":"3bd23390-7108-11ea-8600-afc672063050","site":"hl","status":"on","deleted":false,"overridePredictiveRPM":false,"created":"2022-12-19T19:59:53.000Z","updated":"2024-11-05T21:03:43.000Z","createdBy":"liallison@redventures.com","updatedBy":"mrobinson@rvohealth.com","isTest":false,"overridePredictiveRPMType":"none","rewardType":"","customModel":false,"holdout":"","sdapiTestName":"","modelType":"","imageMobile":"https://media.post.rvohealth.io/2kLEJX4A3LDe7GGDNr31WST2A26/2024/09/26/2mc75hgmcKGdy2Btow91zCpyUlu.jpeg","color":"#02838d","driverTypeId":"1ed6a315-4241-4254-92ae-17d0570ee038","sailthruAccount":"hl","titleOverride":"The health and wellness newsletter you’ve been looking for ","newsletterSource":"Wellness Wire","id":"3c10d216-ff83-4e7e-8e69-dd0be853dcba","trackingNumber":39699,"adTagIds":["5bfa54a0-cb61-11ea-841d-230b5918b98d"],"articlePlacement":"headerNewsletter","image":"https://healthline-activation-prod.healthline.com/driver-images/Wellness%20Wire%20Relaunch%20-%20Visual%20Driver-732x549-Thumbnail%20(1).jpg","titleOverrideMobile":"The health and wellness newsletter you’ve been looking for ","secondaryNewsletters":[],"descriptionModal":"Interested in exclusive interviews, must-have products, and staying updated with trending news? Wellness Wire has it all, and you don’t want to miss out.","driverType":"headerNewsletter","verticalId":"5474f994-0335-422b-aab5-b87a0410aec6","verticalName":"Wellness Wire","lists":["Wellness Wire"],"name":"lifecycle_header_hl_wewi_newsletter","imageDesktop":"https://healthline-activation-prod.healthline.com/driver-images/Wellness%20Wire%20Relaunch%20-%20Visual%20Driver-700x1076-Desktop%20Driver.jpg","descriptionModalMobile":"Interested in exclusive interviews, must-have products, and staying updated with trending news? Wellness Wire has it all, and you don’t want to miss out.","driverPlacementId":"d5b8e667-55c1-4a6d-b05d-728a1733109b","campaignName":"lifecycle_header_hl_wewi_newsletter_39699","productId":"lifecycle_header_hl_wewi_newsletter_39699","_uuid":"mdf023cc0-853f-415a-9fa6-5455aaf12c12mpd_headerNewsletter_c54448fb-575c-413d-993f-5cf346330a9f","cpm":9.210263698372723e+306}},"travelerDisabledReasons":["User is located outside the US (SG)"]},"siteNav":{"header":{"branding":{"logo":"https://media.post.rvohealth.io/wp-content/uploads/2022/08/logo-3.png","enabled":false,"icon":"https://media.post.rvohealth.io/wp-content/uploads/2022/09/skincare-hub-iconSYMBOL-copy-2.png","title":"Healthline Skin Care","columns":[{"title":"Welcome to Healthline Skin Care","text":["We’re getting real about skin care. Healthline is launching our latest Skin Care initiative to help you care for your body’s biggest organ, no matter what your skin type, tone, gender or age. We’re here to be your trusted resource as you navigate the intricate, intimate world of personalized skin care. Here’s to nourishing the skin you’re in."],"column":{"title":"Explore Skin Care","links":[{"title":"Letter from the Editor: Getting Real about Skin Care","url":"https://www.healthline.com/health/beauty-skin-care/letter-from-the-editor-getting-real-about-skin-care","image":"https://media.post.rvohealth.io/wp-content/uploads/2022/09/HL-Skin_Care_Launch-Letter_from_the_Editor-732x549-Thumbnail.jpg"},{"title":"Quiz: What’s Your Skin Type?","url":"https://www.healthline.com/health/beauty-skin-care/skincare-quiz-whats-your-skin-type","image":"https://media.post.rvohealth.io/wp-content/uploads/2022/08/neutrogena_thumb_GIF_732x549.gif"},{"title":"Dr. Adeline Kikam is Addressing Inequity in Skin Care","url":"https://www.healthline.com/health/dr-kikam-is-addressing-the-inequity-within-skin-care-heres-how","image":"https://media.post.rvohealth.io/wp-content/uploads/2022/09/Dr.Kikam-thumbail.jpg"}]}}]},"links":[{"title":"Health Conditions","columns":[{"title":"Featured","columns":1,"columnButton":{"link":"/conditions","text":"All"},"links":[{"title":"Breast Cancer","url":"/breast-cancer"},{"title":"IBD ","url":"/inflammatory-bowel-disease"},{"title":"Migraine","url":"/migraine"},{"title":"Multiple Sclerosis (MS)","url":"/multiple-sclerosis"},{"title":"Rheumatoid Arthritis","url":"/rheumatoid-arthritis"},{"title":"Type 2 Diabetes","url":"/type-2-diabetes"},{"title":"Sponsored Topics","url":"/sponsored-topics"}]},{"title":"Articles","columns":3,"columnButton":{"link":"/directory/topics","text":"All"},"links":[{"title":"Acid Reflux","url":"/health/gerd"},{"title":"ADHD","url":"/health/adhd"},{"title":"Allergies","url":"/health/allergies"},{"title":"Alzheimer's \u0026 Dementia","url":"/health/alzheimers-disease"},{"title":"Bipolar Disorder","url":"/health/bipolar-disorder"},{"title":"Cancer","url":"/health/cancer"},{"title":"Crohn's Disease","url":"/health/crohns-disease"},{"title":"Chronic Pain","url":"/health/chronic-pain"},{"title":"Cold \u0026 Flu","url":"/health/cold-flu"},{"title":"COPD","url":"/health/copd"},{"title":"Depression","url":"/health/depression"},{"title":"Fibromyalgia","url":"/health/fibromyalgia"},{"title":"Heart Disease","url":"/health/heart-disease"},{"title":"High Cholesterol","url":"/health/high-cholesterol"},{"title":"HIV","url":"/health/hiv-aids"},{"title":"Hypertension","url":"/health/high-blood-pressure-hypertension"},{"title":"IPF","url":"/health/managing-idiopathic-pulmonary-fibrosis"},{"title":"Osteoarthritis","url":"/health/osteoarthritis"},{"title":"Psoriasis","url":"/health/psoriasis"},{"title":"Skin Disorders and Care","url":"/health/skin-disorders"},{"title":"STDs","url":"/health/sexually-transmitted-diseases"}]}]},{"title":"Discover","columns":[{"title":"Wellness Topics","columns":1,"columnButton":{"link":"/wellness","text":"All"},"links":[{"title":"Nutrition","url":"/nutrition"},{"title":"Fitness","url":"/fitness"},{"title":"Skin Care","url":"/skincare"},{"title":"Sexual Health","url":"/sexual-health"},{"title":"Women's Health","url":"/program/wellness"},{"title":"Mental Well-Being","url":"/mental-health"},{"title":"Sleep","url":"/sleep"}]},{"title":"Product Reviews","columns":1,"columnButton":{"link":"/reviews","text":"All"},"links":[{"title":"Vitamins \u0026 Supplements","url":"/reviews/vitamin-and-supplement-products"},{"title":"Sleep","url":"/reviews/sleep-products"},{"title":"Mental Health","url":"/reviews/mental-health-services-and-products"},{"title":"Nutrition","url":"/reviews/nutrition-products"},{"title":"At-Home Testing","url":"/reviews/at-home-testing-products"},{"title":"CBD","url":"/reviews/cbd-products"},{"title":"Men’s Health","url":"/reviews/mens-health-products"}]},{"title":"Original Series","columns":1,"columnButton":{"link":"/series","text":"All"},"links":[{"title":"Fresh Food Fast","url":"/content-series/fresh-food-fast","description":"Food hacks to make eating healthier, easier.","image":"https://media.post.rvohealth.io/wp-content/uploads/2021/07/FFF_lead-logo4-23.png?w=240\u0026h=240"},{"title":"Diagnosis Diaries","url":"/content-series/diagnosis-diaries","description":"Real diagnosis stories from people who get it.","image":"https://media.post.rvohealth.io/wp-content/uploads/2022/07/HL-icon-diagnosis-diaries-1.png"},{"title":"You’re Not Alone","url":"/content-series/youre-not-alone","description":"Stories from real people that destigmatize mental health conditions.","image":"https://media.post.rvohealth.io/wp-content/uploads/2022/07/HL-icon-youre-not-alone-1.png"},{"title":"Present Tense","url":"/content-series/present-tense","description":"Real-world mindfulness for busy people.","image":"https://media.post.rvohealth.io/wp-content/uploads/2021/05/HL-Content_Series-Present_Tense-Series_Logo-500x500-Series_Logo.png"}]},{"title":"Video Series","columns":1,"columnButton":{"link":"/video","text":"All"},"links":[{"title":"Youth in Focus","url":"/health/video/youth-in-focus","description":"Mental health challenges facing our youth.","image":"https://media.post.rvohealth.io/wp-content/uploads/2022/07/240x240-Youth-in-Focus.png"},{"title":"Healthy Harvest","url":"/health/nutrition/video/healthy-harvest","description":"Meet your food, from farm to table.","image":"https://media.post.rvohealth.io/wp-content/uploads/2022/09/Healthy_harvest_icon_Artboard-4-transformed.png"},{"title":"Through An Artist's Eye","url":"/health/breast-cancer/metastatic-breast-cancer-artist-eye","description":"A breast cancer story told through art.","image":"https://media.post.rvohealth.io/wp-content/uploads/2023/10/Through_an_artists_eye-07.png"},{"title":"Future of Health","url":"/health/video/future-of-health","description":"Innovations shaping the future of health.","image":"https://media.post.rvohealth.io/wp-content/uploads/2022/07/HL-icon-future-of-health-1.png"}]}]},{"title":"Plan","columns":[{"title":"Health Challenges","columns":1,"links":[{"title":"Mindful Eating","url":"/newsletter-signup/mindfulness-challenge"},{"title":"Sugar Savvy","url":"/newsletter-signup/sugar-challenge"},{"title":"Move Your Body","url":"/newsletter-signup/move-your-body-challenge"},{"title":"Gut Health","url":"/newsletter-signup/gut-check-challenge"},{"title":"Mood Foods","url":"/newsletter-signup/mood-foods-challenge"},{"title":"Align Your Spine","url":"/newsletter-signup/align-your-spine-challenge"}]},{"title":"Find Care","columns":1,"columnButton":{"link":"https://care.healthline.com/find-care/specialty","text":"All"},"links":[{"title":"Primary Care","url":"https://care.healthline.com/find-care/specialty/primary-care-doctors?ref=global"},{"title":"Mental Health","url":"https://care.healthline.com/find-care/specialty/mental-health-professional?ref=global"},{"title":"OB-GYN","url":"https://care.healthline.com/find-care/specialty/obstetrics-gynecology?ref=global"},{"title":"Dermatologists","url":"https://care.healthline.com/find-care/specialty/dermatology?ref=global"},{"title":"Neurologists","url":"https://care.healthline.com/find-care/specialty/neurology?ref=global"},{"title":"Cardiologists","url":"https://care.healthline.com/find-care/specialty/cardiology?ref=global"},{"title":"Orthopedists","url":"https://care.healthline.com/find-care/specialty/orthopedic-surgery?ref=global"}]},{"title":"Lifestyle Quizzes","columns":1,"links":[{"title":"Weight Management","url":"/nutrition/weight-management-quiz"},{"title":"Am I Depressed? A Quiz for Teens","url":"/health/depression/teenage-quiz"},{"title":"Are You a Workaholic?","url":"/health/mental-health/quiz-are-you-a-workaholic#quiz-are-you-a-workaholic"},{"title":"How Well Do You Sleep?","url":"/health/healthy-sleep/quiz-how-well-do-you-sleep"}]},{"title":"Tools \u0026 Resources","columns":1,"links":[{"title":"Health News","url":"https://www.healthline.com/health-news","target":"_blank"},{"title":"Find a Diet","url":"https://activation.healthline.com/assessment/assessment/diets/prompt/1?v=1\u0026tc=120226\u0026subid=hl_dietfinder_1_","target":"_blank"},{"title":"Find Healthy Snacks","url":"https://activation.healthline.com/assessment/assessment/pregnancy-snacks/prompt/1?v=1","target":"_blank"},{"title":"Drugs A-Z","url":"/drugs"},{"title":"Health A-Z","url":"https://www.healthline.com/directory/topics"}]}]},{"title":"Connect","columns":[{"title":"Find Your Bezzy Community","subtitle":"Bezzy communities provide meaningful connections with others living with chronic conditions. Join Bezzy on the web or mobile app.","columns":3,"columnButton":{"link":"https://www.bezzy.com/?utm_source=healthline\u0026utm_medium=nav-bar-connections","text":"All"},"links":[{"title":"Breast Cancer","label":"Visit the Breat Cancer community","image":"https://media.post.rvohealth.io/wp-content/uploads/2022/01/Bezzy-Breast-Cancer.png","target":"_blank","url":"https://www.bezzybc.com/lp/2/?verzenio\u0026utm_source=healthline\u0026utm_medium=nav-bar-connections","type":"tile"},{"title":"Inflammatory Bowel Disease","label":"Visit the Inflammatory Bowel Disease community","image":"https://media.post.rvohealth.io/wp-content/uploads/2022/01/Bezzy-Inflammatory-Bowel-Disease.png","target":"_blank","url":"https://www.bezzyibd.com/?utm_source=healthline\u0026utm_medium=nav-bar-connections","type":"tile"},{"title":"Depression","label":"Visit the Depression community","image":"https://media.post.rvohealth.io/wp-content/uploads/2024/11/Bezzy-DEP-Icon-Circle.png","target":"_blank","url":"https://www.bezzydepression.com/?auvelity\u0026utm_source=healthline\u0026utm_medium=nav-bar-connections","type":"tile"},{"title":"Migraine","label":"Visit the Migraine community","image":"https://media.post.rvohealth.io/wp-content/uploads/2022/01/Bezzy-Migraine.png","target":"_blank","url":"https://www.bezzymigraine.com/?utm_source=healthline\u0026utm_medium=nav-bar-connections","type":"tile"},{"title":"Multiple Sclerosis","label":"Visit the Multiple Sclerosis community","image":"https://media.post.rvohealth.io/wp-content/uploads/2022/01/Bezzy-Multiple-Sclerosis.png","target":"_blank","url":"https://www.bezzyms.com/?utm_source=healthline\u0026utm_medium=nav-bar-connections","type":"tile"},{"title":"Psoriasis","label":"Visit the Psoriasis community","image":"https://media.post.rvohealth.io/wp-content/uploads/2022/04/Bezzy-PsO.png","target":"_blank","url":"https://www.bezzypsoriasis.com/?utm_source=healthline\u0026utm_medium=nav-bar-connections","type":"tile"}]},{"title":"Follow us on social media","columns":1,"subtitle":"Can't get enough? Connect with us for all things health.","widget":"social"}]}]},"footer":{"links":[{"sponsored":false,"title":"About Us","url":"/about"},{"sponsored":false,"title":"Contact Us","url":"/about/contact-us"},{"sponsored":false,"location":"US","title":"Terms of Use","url":"/terms-of-use"},{"sponsored":false,"title":"Privacy Policy","url":"/privacy-policy"},{"sponsored":false,"title":"Privacy Settings","url":"/privacy-settings"},{"title":"Advertising Policy","url":"/advertising-policy"},{"sponsored":false,"title":"Health Topics","url":"/directory/topics"},{"sponsored":false,"title":"Sitemap","url":"/sitemap"},{"sponsored":false,"title":"Medical Affairs","url":"/medical-team"},{"sponsored":false,"title":"Content Integrity","url":"/about/content-integrity"},{"sponsored":false,"title":"Newsletters","url":"/newsletter-signup"},{"sponsored":false,"location":"US","title":"Your Privacy Choices","url":"https://privacyportal.onetrust.com/webform/b45407c6-ee79-4a08-912e-02ce898f9a14/2933b890-b659-41c5-86d8-a2375e0d7776","appendAnonymousId":true,"privacyOptOutLink":true}]}},"stylesheetIds":["0","b7n1on","114pms8","x9mcui","ghahvh","182h2jb","1ewa140","7977ts","hh42uh","3jro8","w2pt6r","1c2ok3c","j5n0jw","a10gts","17ztj4b","t753mo","1r1p1p8","d2znx6","12weawj","f0t0lw","1l95nvm","zya54r","fdjy12","1m3pkrv","m260rd","tqpz90","1w3ble7","cs3emt","x4xfyn","qzkqso","wyg90z","m8s3k4","10aca47","18bsjiu","1g6cesj","12mc611","1bqkt1y","yc5e1l","1wyiq3l","yer60s","ajcamw","dke6ht","16uojuo","10adefi","1n6ef6i","1wtf0mw","8sow18","1q1spi4","1dm1ger","bbu8su","1bdb0zy","lembgb","1a25cod","v5umvf","1ur4f3m","2dofw9","ifmqwy","1wm8u43","1hjaa0k","1jpwf16","1j2d96m","11egx89","pdceuf","16m9poz","bcus5s","1fteite","8q0s1n","1h1rean","blwnmv","z468a2","jy1umg","1q67gt9","quwpxp","7u7i0a","20w1gi","1t05dkn","1sq15os","1ubyuqj","1vedeqe","82r5pg","npv6dx","lizeih","488q2e","1d8h8gm","1g3kp27","1r7frvz","lm0pdr","rwmw5v","1lyqwde","1767n2d","1fb1nmp","sqa1yu","8he51f","1pz7193","onvglr","ysgmro","prb4v6","vhteyv","79elbk","i9gxme","1dytfcg","1dppxl0","1b2ri56","uktbta","1xceiwh","10ohy14","lb03wr","34bq4y","1qz7cpo","159kw12","16bllps","1xx5q6","1us2gxx","11upubx","t5u34a","d2oo9m","s2uf1z","s65yls","huujs8","1vtxghn","d9t9tq"]}</script><script type="text/javascript" src="https://assets.healthline.com/_next/vendor-8da18-legacy.js" crossorigin="anonymous" async=""></script><script type="text/javascript" src="https://assets.healthline.com/_next/lib-939ee-legacy.js" crossorigin="anonymous" async=""></script><script type="text/javascript" src="https://assets.healthline.com/_next/felib-core-f46c4-legacy.js" crossorigin="anonymous" async=""></script><script type="text/javascript" src="https://assets.healthline.com/_next/b4a658d5-9338-4cd3-9e5d-9d0a6ca8e30c/hl/pages/infinite.js-legacy.js" crossorigin="anonymous" async=""></script><script src="https://js.sentry-cdn.com/8bc674d734914b3f8179f84e9edb0faa.min.js" crossorigin="anonymous"></script><script> window.Sentry && Sentry.onLoad(function() { const o = {"dsn":"https://8bc674d734914b3f8179f84e9edb0faa@o62581.ingest.sentry.io/248102","sampleRate":0.1,"release":"12037910632","environment":"prod"}; o.allowUrls = [/https:\/\/assets.healthline.com\//]; o.ignoreErrors = [/Error compiling fragment shader/i,/Float textures are not supported/i,/Can't execute code from a freed script/i,/enough storage/i,/out of memory/i,/PP\(/i,/Synchronous XHR in page dismissal./i,/Failed to load.*ingest.make.rvapps.io\/v2\/t/i,/Failed to load.*ingest.make.rvohealth.com\/v2\/t/i,/The operation was aborted/i,/Blocked a restricted frame with origin/i,/cancelled/i,/cancelado/i]; if (window.beforeSend) o.beforeSend = beforeSend; Sentry.init(o); Sentry.configureScope(function (scope) { scope.setTag('environment', 'prod') }); if (window.initSentry) initSentry(); }); </script><div> <script type="application/ld+json">{"@context":"https://schema.org","publisher":{"@type":"Organization","name":"Healthline Media","logo":{"@type":"ImageObject","url":"https://media.post.rvohealth.io/wp-content/uploads/2023/09/Healthline-Black-Logo.png"}},"@type":"MedicalWebPage","headline":"A Simple Guide to the Endocannabinoid System","description":"The endocannabinoid is a complex system that still isn't fully understood. We'll go over what experts do know about it, including how it works, the ways it interacts with cannabis, and theories about its role in different conditions.","keywords":"endocannabinoid system","author":{"@type":"Person","name":"Crystal Raypole"},"lastReviewed":"2019-05-17T14:03:13Z","url":"https://www.healthline.com/health/endocannabinoid-system","datePublished":"2019-05-17T14:03:13Z","dateModified":"2019-05-17T14:03:13Z","articleSection":"Uncategorized","correction":{"@type":"CorrectionComment","text":"","datePublished":"2019-05-17"},"reviewedBy":"Alan Carter, Pharm.D.","thumbnail":["https://media.post.rvohealth.io/wp-content/uploads/2019/04/Doctor_Talk_Female_Laptop-732x549-Thumbnail.jpg"]}</script></div><noscript><img alt="" src="http://b.scorecardresearch.com/p?c1=2&c2=38584006&cv=3.9&cj=1&comscorekw=main"/></noscript><span>  </span><div id="menu-host"></div></body></html>