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class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/105758748/Characterizing_the_EEG_Features_of_Inspiring_Designers_with_Functional_Terms"><img alt="Research paper thumbnail of Characterizing the EEG Features of Inspiring Designers with Functional Terms" class="work-thumbnail" src="https://attachments.academia-assets.com/105137844/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/105758748/Characterizing_the_EEG_Features_of_Inspiring_Designers_with_Functional_Terms">Characterizing the EEG Features of Inspiring Designers with Functional Terms</a></div><div class="wp-workCard_item"><span>Human-Computer Interaction. Theories, Methods, and Human Issues</span><span>, 2018</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="8121a82edc06e2360a8ce5bc82ee2689" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":105137844,"asset_id":105758748,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/105137844/download_file?st=MTczMjczOTk3Myw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="105758748"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="105758748"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 105758748; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=105758748]").text(description); $(".js-view-count[data-work-id=105758748]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 105758748; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='105758748']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 105758748, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "8121a82edc06e2360a8ce5bc82ee2689" } } $('.js-work-strip[data-work-id=105758748]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":105758748,"title":"Characterizing the EEG Features of Inspiring Designers with Functional Terms","translated_title":"","metadata":{"publisher":"Springer International Publishing","grobid_abstract":"This paper constructed an inspiring database containing functional terms, which was taken as the source of external stimuli provided to designers. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="105758747"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/105758747/Design_optimization_by_integrating_limited_simulation_data_and_shape_engineering_knowledge_with_Bayesian_optimization_BO_DK4DO_"><img alt="Research paper thumbnail of Design optimization by integrating limited simulation data and shape engineering knowledge with Bayesian optimization (BO-DK4DO)" class="work-thumbnail" src="https://attachments.academia-assets.com/105137864/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/105758747/Design_optimization_by_integrating_limited_simulation_data_and_shape_engineering_knowledge_with_Bayesian_optimization_BO_DK4DO_">Design optimization by integrating limited simulation data and shape engineering knowledge with Bayesian optimization (BO-DK4DO)</a></div><div class="wp-workCard_item"><span>Journal of Intelligent Manufacturing</span><span>, 2020</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="ca0d613ada4778b047f312fa3040be57" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":105137864,"asset_id":105758747,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/105137864/download_file?st=MTczMjczOTk3Myw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="105758747"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="105758747"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 105758747; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=105758747]").text(description); $(".js-view-count[data-work-id=105758747]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 105758747; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='105758747']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 105758747, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "ca0d613ada4778b047f312fa3040be57" } } $('.js-work-strip[data-work-id=105758747]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":105758747,"title":"Design optimization by integrating limited simulation data and shape engineering knowledge with Bayesian optimization (BO-DK4DO)","translated_title":"","metadata":{"publisher":"Springer Science and Business Media LLC","grobid_abstract":"Surrogate models have been widely studied for optimization tasks in the domain of engineering design. However, the expensive and time-consuming simulation cycles needed for complex products always result in limited simulation data, which brings a challenge for building high accuracy surrogate models because of the incomplete information contained in the limited simulation data. Therefore, a method that builds a surrogate model and conducts design optimization by integrating limited simulation data and engineering knowledge through Bayesian optimization (BO-DK4DO) is presented. In this method, the shape engineering knowledge is considered and used as derivative information which is integrated with the limited simulation data with a Gaussian process (GP). Then the GP is updated sequentially by sampling new simulation data and the optimal design solutions are found by maximizing the GP. The aim of BO-DK4DO is to significantly reduce the required number of computer simulations for finding optimal design solutions. The BO-DK4DO is verified by using benchmark functions and an engineering design problem: hot rod rolling. In all scenarios, the BO-DK4DO shows faster convergence rate than the general Bayesian optimization without integrating engineering knowledge, which means the required amount of data is decreased.","publication_date":{"day":null,"month":null,"year":2020,"errors":{}},"publication_name":"Journal of Intelligent Manufacturing","grobid_abstract_attachment_id":105137864},"translated_abstract":null,"internal_url":"https://www.academia.edu/105758747/Design_optimization_by_integrating_limited_simulation_data_and_shape_engineering_knowledge_with_Bayesian_optimization_BO_DK4DO_","translated_internal_url":"","created_at":"2023-08-19T17:55:07.465-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":24656298,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":105137864,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/105137864/thumbnails/1.jpg","file_name":"s10845-020-01551-820230820-1-qh8944.pdf","download_url":"https://www.academia.edu/attachments/105137864/download_file?st=MTczMjczOTk3Myw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Design_optimization_by_integrating_limit.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/105137864/s10845-020-01551-820230820-1-qh8944-libre.pdf?1692497769=\u0026response-content-disposition=attachment%3B+filename%3DDesign_optimization_by_integrating_limit.pdf\u0026Expires=1732743573\u0026Signature=Y9zRsQktUCl2rFoG6WWKbzkB9FHAHTMw5pDpt0q-bN6WlBpEdJShmPmN-7fof~Winyw4Ayzc2v4s0ijKozRFCQ4jeLn-xjETabDpC1fF4EnXtWAHMh~UkogXTlxtBvlnAZvzFfqjjGLXdRXxAhs5WnuPeouWmcA3iCXb-WAGtIhWE~xFvqAeNhftVQvxmi-QDF9pL4pnxJVqbd1J35HqMxehhsFVZHslQ8YCpSHsjd1fsCl-mXQGQ9CqHFBaU9UISUF-3l1YdamJbRwRU5ryWMVvf7T7yLhueuHfZhka0ddeCc0pZfS70sK9ncLzegdPOHMtDB1WhRHskILuFJYE7A__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Design_optimization_by_integrating_limited_simulation_data_and_shape_engineering_knowledge_with_Bayesian_optimization_BO_DK4DO_","translated_slug":"","page_count":19,"language":"en","content_type":"Work","owner":{"id":24656298,"first_name":"Jia","middle_initials":null,"last_name":"Hao","page_name":"JiaHao2","domain_name":"independent","created_at":"2015-01-11T07:08:00.159-08:00","display_name":"Jia Hao","url":"https://independent.academia.edu/JiaHao2"},"attachments":[{"id":105137864,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/105137864/thumbnails/1.jpg","file_name":"s10845-020-01551-820230820-1-qh8944.pdf","download_url":"https://www.academia.edu/attachments/105137864/download_file?st=MTczMjczOTk3Myw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Design_optimization_by_integrating_limit.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/105137864/s10845-020-01551-820230820-1-qh8944-libre.pdf?1692497769=\u0026response-content-disposition=attachment%3B+filename%3DDesign_optimization_by_integrating_limit.pdf\u0026Expires=1732743573\u0026Signature=Y9zRsQktUCl2rFoG6WWKbzkB9FHAHTMw5pDpt0q-bN6WlBpEdJShmPmN-7fof~Winyw4Ayzc2v4s0ijKozRFCQ4jeLn-xjETabDpC1fF4EnXtWAHMh~UkogXTlxtBvlnAZvzFfqjjGLXdRXxAhs5WnuPeouWmcA3iCXb-WAGtIhWE~xFvqAeNhftVQvxmi-QDF9pL4pnxJVqbd1J35HqMxehhsFVZHslQ8YCpSHsjd1fsCl-mXQGQ9CqHFBaU9UISUF-3l1YdamJbRwRU5ryWMVvf7T7yLhueuHfZhka0ddeCc0pZfS70sK9ncLzegdPOHMtDB1WhRHskILuFJYE7A__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":422,"name":"Computer Science","url":"https://www.academia.edu/Documents/in/Computer_Science"},{"id":46604,"name":"Intelligent Manufacturing","url":"https://www.academia.edu/Documents/in/Intelligent_Manufacturing"},{"id":55523,"name":"Engineering Optimization","url":"https://www.academia.edu/Documents/in/Engineering_Optimization"},{"id":96825,"name":"Manufacturing Engineering","url":"https://www.academia.edu/Documents/in/Manufacturing_Engineering"},{"id":535039,"name":"Bayesian Optimization","url":"https://www.academia.edu/Documents/in/Bayesian_Optimization"}],"urls":[{"id":33510685,"url":"http://link.springer.com/content/pdf/10.1007/s10845-020-01551-8.pdf"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="105758746"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/105758746/Simultaneous_determination_of_columbianetin_%CE%B2_d_glucopyranoside_and_columbianetin_in_a_biological_sample_by_high_performance_liquid_chromatography_with_fluorescence_detection_and_identification_of_other_columbianetin_%CE%B2_d_glucopyranoside_metabolites_by_ultra_high_performance_liquid_chromatography_"><img alt="Research paper thumbnail of Simultaneous determination of columbianetin-β-d-glucopyranoside and columbianetin in a biological sample by high-performance liquid chromatography with fluorescence detection and identification of other columbianetin-β-d-glucopyranoside metabolites by ultra high-performance liquid chromatography ..." class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/105758746/Simultaneous_determination_of_columbianetin_%CE%B2_d_glucopyranoside_and_columbianetin_in_a_biological_sample_by_high_performance_liquid_chromatography_with_fluorescence_detection_and_identification_of_other_columbianetin_%CE%B2_d_glucopyranoside_metabolites_by_ultra_high_performance_liquid_chromatography_">Simultaneous determination of columbianetin-β-d-glucopyranoside and columbianetin in a biological sample by high-performance liquid chromatography with fluorescence detection and identification of other columbianetin-β-d-glucopyranoside metabolites by ultra high-performance liquid chromatography ...</a></div><div class="wp-workCard_item"><span>Journal of pharmaceutical and biomedical analysis</span><span>, Jan 10, 2018</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Columbianetin-β-d-glucopyranoside (CBG) and its metabolite columbianetin (CBN) are the bioactive ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Columbianetin-β-d-glucopyranoside (CBG) and its metabolite columbianetin (CBN) are the bioactive constituents of Angelicae pubescentis radix (APR). They exhibit the anti-platelet aggregation, anti-inflammatory and analgesic properties. The absorption, distribution, metabolism and excretion (ADME) of CBG has not been reported to date. Both high-performance liquid chromatography with fluorescence detection and ultra high-performance liquid chromatography coupled with quadrupole-time-of-flight mass spectrometry methods were developed and validated for the study of ADME of CBG. It was found that CBG could be catabolized into its active metabolite CBN in vivo. The absolute bioavailability of columbianetin-β-d-glucopyranoside was 5.63 ± 4.42%. The other co-existing constituents from the APR ethanol extract could enhance the absorption of CBG. CBG and CBN were rapidly and broadly distributed in the stomach, ovary, kidney, liver, spleen, lung, muscles, heart and brain. Higher levels of accu...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="105758746"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="105758746"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 105758746; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=105758746]").text(description); $(".js-view-count[data-work-id=105758746]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 105758746; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='105758746']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 105758746, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=105758746]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":105758746,"title":"Simultaneous determination of columbianetin-β-d-glucopyranoside and columbianetin in a biological sample by high-performance liquid chromatography with fluorescence detection and identification of other columbianetin-β-d-glucopyranoside metabolites by ultra high-performance liquid chromatography ...","translated_title":"","metadata":{"abstract":"Columbianetin-β-d-glucopyranoside (CBG) and its metabolite columbianetin (CBN) are the bioactive constituents of Angelicae pubescentis radix (APR). They exhibit the anti-platelet aggregation, anti-inflammatory and analgesic properties. The absorption, distribution, metabolism and excretion (ADME) of CBG has not been reported to date. Both high-performance liquid chromatography with fluorescence detection and ultra high-performance liquid chromatography coupled with quadrupole-time-of-flight mass spectrometry methods were developed and validated for the study of ADME of CBG. It was found that CBG could be catabolized into its active metabolite CBN in vivo. The absolute bioavailability of columbianetin-β-d-glucopyranoside was 5.63 ± 4.42%. The other co-existing constituents from the APR ethanol extract could enhance the absorption of CBG. CBG and CBN were rapidly and broadly distributed in the stomach, ovary, kidney, liver, spleen, lung, muscles, heart and brain. Higher levels of accu...","publication_date":{"day":10,"month":1,"year":2018,"errors":{}},"publication_name":"Journal of pharmaceutical and biomedical analysis"},"translated_abstract":"Columbianetin-β-d-glucopyranoside (CBG) and its metabolite columbianetin (CBN) are the bioactive constituents of Angelicae pubescentis radix (APR). They exhibit the anti-platelet aggregation, anti-inflammatory and analgesic properties. The absorption, distribution, metabolism and excretion (ADME) of CBG has not been reported to date. Both high-performance liquid chromatography with fluorescence detection and ultra high-performance liquid chromatography coupled with quadrupole-time-of-flight mass spectrometry methods were developed and validated for the study of ADME of CBG. It was found that CBG could be catabolized into its active metabolite CBN in vivo. The absolute bioavailability of columbianetin-β-d-glucopyranoside was 5.63 ± 4.42%. The other co-existing constituents from the APR ethanol extract could enhance the absorption of CBG. CBG and CBN were rapidly and broadly distributed in the stomach, ovary, kidney, liver, spleen, lung, muscles, heart and brain. Higher levels of accu...","internal_url":"https://www.academia.edu/105758746/Simultaneous_determination_of_columbianetin_%CE%B2_d_glucopyranoside_and_columbianetin_in_a_biological_sample_by_high_performance_liquid_chromatography_with_fluorescence_detection_and_identification_of_other_columbianetin_%CE%B2_d_glucopyranoside_metabolites_by_ultra_high_performance_liquid_chromatography_","translated_internal_url":"","created_at":"2023-08-19T17:55:07.268-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":24656298,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Simultaneous_determination_of_columbianetin_β_d_glucopyranoside_and_columbianetin_in_a_biological_sample_by_high_performance_liquid_chromatography_with_fluorescence_detection_and_identification_of_other_columbianetin_β_d_glucopyranoside_metabolites_by_ultra_high_performance_liquid_chromatography_","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":24656298,"first_name":"Jia","middle_initials":null,"last_name":"Hao","page_name":"JiaHao2","domain_name":"independent","created_at":"2015-01-11T07:08:00.159-08:00","display_name":"Jia Hao","url":"https://independent.academia.edu/JiaHao2"},"attachments":[],"research_interests":[{"id":523,"name":"Chemistry","url":"https://www.academia.edu/Documents/in/Chemistry"},{"id":524,"name":"Analytical Chemistry","url":"https://www.academia.edu/Documents/in/Analytical_Chemistry"},{"id":4656,"name":"Chromatography","url":"https://www.academia.edu/Documents/in/Chromatography"},{"id":7698,"name":"Fluorescence","url":"https://www.academia.edu/Documents/in/Fluorescence"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":163275,"name":"Tandem Mass Spectrometry","url":"https://www.academia.edu/Documents/in/Tandem_Mass_Spectrometry"},{"id":178360,"name":"Urine","url":"https://www.academia.edu/Documents/in/Urine"},{"id":204350,"name":"Anti-inflammatory agents","url":"https://www.academia.edu/Documents/in/Anti-inflammatory_agents"},{"id":205461,"name":"Bioavailability","url":"https://www.academia.edu/Documents/in/Bioavailability"},{"id":225787,"name":"High Performance Liquid Chromatography","url":"https://www.academia.edu/Documents/in/High_Performance_Liquid_Chromatography"},{"id":246560,"name":"High Pressure Liquid Chromatography","url":"https://www.academia.edu/Documents/in/High_Pressure_Liquid_Chromatography"},{"id":375054,"name":"Rats","url":"https://www.academia.edu/Documents/in/Rats"},{"id":727024,"name":"ADME","url":"https://www.academia.edu/Documents/in/ADME"},{"id":1136192,"name":"Biological Availability","url":"https://www.academia.edu/Documents/in/Biological_Availability"},{"id":1223894,"name":"Metabolite","url":"https://www.academia.edu/Documents/in/Metabolite"},{"id":3549129,"name":"excretion","url":"https://www.academia.edu/Documents/in/excretion"},{"id":3789884,"name":"Pharmacology and pharmaceutical sciences","url":"https://www.academia.edu/Documents/in/Pharmacology_and_pharmaceutical_sciences"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="105758745"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/105758745/An_evolutionary_computation_based_method_for_creative_design_inspiration_generation"><img alt="Research paper thumbnail of An evolutionary computation based method for creative design inspiration generation" class="work-thumbnail" src="https://attachments.academia-assets.com/105137876/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/105758745/An_evolutionary_computation_based_method_for_creative_design_inspiration_generation">An evolutionary computation based method for creative design inspiration generation</a></div><div class="wp-workCard_item"><span>Journal of Intelligent Manufacturing</span><span>, 2017</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="6f246d5c980043b456d17e831a600bb5" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":105137876,"asset_id":105758745,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/105137876/download_file?st=MTczMjczOTk3Myw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="105758745"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="105758745"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 105758745; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=105758745]").text(description); $(".js-view-count[data-work-id=105758745]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 105758745; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='105758745']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 105758745, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "6f246d5c980043b456d17e831a600bb5" } } $('.js-work-strip[data-work-id=105758745]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":105758745,"title":"An evolutionary computation based method for creative design inspiration generation","translated_title":"","metadata":{"publisher":"Springer Science and Business Media LLC","grobid_abstract":"Product design is an important part of the manufacturing system from a macro point of view. In the design process, creative design is one of the important factors to survive the fierce competition. During creative design process, designers are the most critical component. However, design fixation often negatively influences the design outcomes. Many researches from cognitive science and design science reveal that the presentation of outer information can alleviate design fixation effectively. Among different kinds of outer information, language terms are proved to be effective. This work presents a method of automatically generating language terms as design inspirations based on 500,000 granted patents. This method adopts evolutionary computation as the fundamental algorithm to retrieve language terms from a vocabulary base. To implement the algorithm, the vocabulary is first encoded by high dimensional vectors through word embedding, which is a three layers neural network. Further, two metrics for measuring the inspiration potential of language terms are defined in a computable manner. This work also conducts experiments to validate the method, and the experimental results show that (1) the algorithm is efficient and has the potential to be extended to larger vocabulary; (2) B Jia Hao","publication_date":{"day":null,"month":null,"year":2017,"errors":{}},"publication_name":"Journal of Intelligent Manufacturing","grobid_abstract_attachment_id":105137876},"translated_abstract":null,"internal_url":"https://www.academia.edu/105758745/An_evolutionary_computation_based_method_for_creative_design_inspiration_generation","translated_internal_url":"","created_at":"2023-08-19T17:55:06.893-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":24656298,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":105137876,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/105137876/thumbnails/1.jpg","file_name":"s10845-017-1347-x20230820-1-cs4f30.pdf","download_url":"https://www.academia.edu/attachments/105137876/download_file?st=MTczMjczOTk3Myw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"An_evolutionary_computation_based_method.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/105137876/s10845-017-1347-x20230820-1-cs4f30-libre.pdf?1692497783=\u0026response-content-disposition=attachment%3B+filename%3DAn_evolutionary_computation_based_method.pdf\u0026Expires=1732743573\u0026Signature=c-kyut5bNyNcqtpPETeVcFMiDsixswsRvHh3zAKo7ga5Vjtk1xM0jCwDpL7toGLdaWFD~tqGOFC~5-lkiO1GSSzUsaZLRP5blOKoAMxfpNVA-83JlErkOUot-HA6vX9aEPphfRKg-BdGFqi~~BtkeCySgn~rY81OHPfuHOUHhjI0cRro3I31eSYGhhCA09N-YMWbpTyWe1ENuWBpA1x-HKgNK2XX2kZNqBUQG9dIUOODx7KMHkpRvKP-r4~ESynLBARel5j2NEaFV43Yfi~9QccQLYW6w1fEDspwBx-69yJotpH897ZSSoF8rM~cG50kEqq4HpvXPXxS-NV2FggOWA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"An_evolutionary_computation_based_method_for_creative_design_inspiration_generation","translated_slug":"","page_count":19,"language":"en","content_type":"Work","owner":{"id":24656298,"first_name":"Jia","middle_initials":null,"last_name":"Hao","page_name":"JiaHao2","domain_name":"independent","created_at":"2015-01-11T07:08:00.159-08:00","display_name":"Jia Hao","url":"https://independent.academia.edu/JiaHao2"},"attachments":[{"id":105137876,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/105137876/thumbnails/1.jpg","file_name":"s10845-017-1347-x20230820-1-cs4f30.pdf","download_url":"https://www.academia.edu/attachments/105137876/download_file?st=MTczMjczOTk3Myw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"An_evolutionary_computation_based_method.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/105137876/s10845-017-1347-x20230820-1-cs4f30-libre.pdf?1692497783=\u0026response-content-disposition=attachment%3B+filename%3DAn_evolutionary_computation_based_method.pdf\u0026Expires=1732743573\u0026Signature=c-kyut5bNyNcqtpPETeVcFMiDsixswsRvHh3zAKo7ga5Vjtk1xM0jCwDpL7toGLdaWFD~tqGOFC~5-lkiO1GSSzUsaZLRP5blOKoAMxfpNVA-83JlErkOUot-HA6vX9aEPphfRKg-BdGFqi~~BtkeCySgn~rY81OHPfuHOUHhjI0cRro3I31eSYGhhCA09N-YMWbpTyWe1ENuWBpA1x-HKgNK2XX2kZNqBUQG9dIUOODx7KMHkpRvKP-r4~ESynLBARel5j2NEaFV43Yfi~9QccQLYW6w1fEDspwBx-69yJotpH897ZSSoF8rM~cG50kEqq4HpvXPXxS-NV2FggOWA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":422,"name":"Computer Science","url":"https://www.academia.edu/Documents/in/Computer_Science"},{"id":46604,"name":"Intelligent Manufacturing","url":"https://www.academia.edu/Documents/in/Intelligent_Manufacturing"},{"id":59487,"name":"Computation","url":"https://www.academia.edu/Documents/in/Computation"},{"id":96825,"name":"Manufacturing Engineering","url":"https://www.academia.edu/Documents/in/Manufacturing_Engineering"}],"urls":[{"id":33510684,"url":"http://link.springer.com/content/pdf/10.1007/s10845-017-1347-x.pdf"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="105758744"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/105758744/The_Method_of_Failure_Data_Processing_Analysis_of_Filling_System_in_Launching_Site_Based_on_Bayesian_Method"><img alt="Research paper thumbnail of The Method of Failure Data Processing Analysis of Filling System in Launching Site Based on Bayesian Method" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/105758744/The_Method_of_Failure_Data_Processing_Analysis_of_Filling_System_in_Launching_Site_Based_on_Bayesian_Method">The Method of Failure Data Processing Analysis of Filling System in Launching Site Based on Bayesian Method</a></div><div class="wp-workCard_item"><span>Applied Mechanics and Materials</span><span>, 2014</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The high reliability and the short times carried of quantitative risk assessment of Filling syste...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The high reliability and the short times carried of quantitative risk assessment of Filling system in launching site, the failure data is small sample data. In this paper, we will focus on these small sample data and take processing analysis. A method based on Bayesian method of failure data processing analysis of Filling system has been proposed, which firstly analyzes the characteristic of failure data of Filling system. Secondly, we classify the failure data into running failure data and demanding data according to the data types, and further analyze various uncertainty distributions under this two kinds of data type. What’s more, we use Bayesian method to solve the problems of various failure data. Lastly, we combine the real circumstance of Filling system and take the Filling system as example, and choose the filling pump, shut-off valve and pneumatic ball valve these three different failure types to use Bayesian method to analyze, and obtain various prior distributions and pos...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="105758744"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="105758744"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 105758744; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=105758744]").text(description); $(".js-view-count[data-work-id=105758744]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 105758744; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='105758744']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 105758744, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=105758744]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":105758744,"title":"The Method of Failure Data Processing Analysis of Filling System in Launching Site Based on Bayesian Method","translated_title":"","metadata":{"abstract":"The high reliability and the short times carried of quantitative risk assessment of Filling system in launching site, the failure data is small sample data. 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Lastly, we combine the real circumstance of Filling system and take the Filling system as example, and choose the filling pump, shut-off valve and pneumatic ball valve these three different failure types to use Bayesian method to analyze, and obtain various prior distributions and pos...","publisher":"Trans Tech Publications","publication_date":{"day":null,"month":null,"year":2014,"errors":{}},"publication_name":"Applied Mechanics and Materials"},"translated_abstract":"The high reliability and the short times carried of quantitative risk assessment of Filling system in launching site, the failure data is small sample data. In this paper, we will focus on these small sample data and take processing analysis. A method based on Bayesian method of failure data processing analysis of Filling system has been proposed, which firstly analyzes the characteristic of failure data of Filling system. Secondly, we classify the failure data into running failure data and demanding data according to the data types, and further analyze various uncertainty distributions under this two kinds of data type. What’s more, we use Bayesian method to solve the problems of various failure data. Lastly, we combine the real circumstance of Filling system and take the Filling system as example, and choose the filling pump, shut-off valve and pneumatic ball valve these three different failure types to use Bayesian method to analyze, and obtain various prior distributions and pos...","internal_url":"https://www.academia.edu/105758744/The_Method_of_Failure_Data_Processing_Analysis_of_Filling_System_in_Launching_Site_Based_on_Bayesian_Method","translated_internal_url":"","created_at":"2023-08-19T17:55:06.228-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":24656298,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"The_Method_of_Failure_Data_Processing_Analysis_of_Filling_System_in_Launching_Site_Based_on_Bayesian_Method","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":24656298,"first_name":"Jia","middle_initials":null,"last_name":"Hao","page_name":"JiaHao2","domain_name":"independent","created_at":"2015-01-11T07:08:00.159-08:00","display_name":"Jia Hao","url":"https://independent.academia.edu/JiaHao2"},"attachments":[],"research_interests":[{"id":48,"name":"Engineering","url":"https://www.academia.edu/Documents/in/Engineering"},{"id":2009,"name":"Data Mining","url":"https://www.academia.edu/Documents/in/Data_Mining"},{"id":581652,"name":"Data Processing","url":"https://www.academia.edu/Documents/in/Data_Processing"},{"id":1032783,"name":"Bayesian Probability","url":"https://www.academia.edu/Documents/in/Bayesian_Probability"}],"urls":[{"id":33510683,"url":"http://www.scientific.net/AMM.644-650.2537.pdf"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="105758743"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/105758743/Study_on_High_Performance_Simulation_Computer_for_Large_Scale_System_of_Systems_Simulation"><img alt="Research paper thumbnail of Study on High-Performance Simulation Computer for Large-Scale System of Systems Simulation" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/105758743/Study_on_High_Performance_Simulation_Computer_for_Large_Scale_System_of_Systems_Simulation">Study on High-Performance Simulation Computer for Large-Scale System of Systems Simulation</a></div><div class="wp-workCard_item"><span>Applied Mechanics and Materials</span><span>, 2014</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The high-performance parallel computing (HPPC) has a better overall performance and higher produc...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The high-performance parallel computing (HPPC) has a better overall performance and higher productivity, for a generical large-scale army equipment system of systems (AESoS) simulation, and the runtime efficiency can be multiplied several tenfold to several hundredfold. The requirement analysis of simulation framework of AESoS based on HPPC was proposed. After the simulation framework of AESoS based on HPPC and its key techniques were discussed, the simulation framework of AESoS Based HPPC was designed. it is of great significance to offer certain references for the engineering application in the simulation fields of AESoS based on HPPC.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="105758743"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="105758743"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 105758743; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=105758743]").text(description); $(".js-view-count[data-work-id=105758743]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 105758743; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='105758743']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 105758743, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=105758743]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":105758743,"title":"Study on High-Performance Simulation Computer for Large-Scale System of Systems Simulation","translated_title":"","metadata":{"abstract":"The high-performance parallel computing (HPPC) has a better overall performance and higher productivity, for a generical large-scale army equipment system of systems (AESoS) simulation, and the runtime efficiency can be multiplied several tenfold to several hundredfold. The requirement analysis of simulation framework of AESoS based on HPPC was proposed. After the simulation framework of AESoS based on HPPC and its key techniques were discussed, the simulation framework of AESoS Based HPPC was designed. it is of great significance to offer certain references for the engineering application in the simulation fields of AESoS based on HPPC.","publisher":"Trans Tech Publications","publication_date":{"day":null,"month":null,"year":2014,"errors":{}},"publication_name":"Applied Mechanics and Materials"},"translated_abstract":"The high-performance parallel computing (HPPC) has a better overall performance and higher productivity, for a generical large-scale army equipment system of systems (AESoS) simulation, and the runtime efficiency can be multiplied several tenfold to several hundredfold. The requirement analysis of simulation framework of AESoS based on HPPC was proposed. After the simulation framework of AESoS based on HPPC and its key techniques were discussed, the simulation framework of AESoS Based HPPC was designed. it is of great significance to offer certain references for the engineering application in the simulation fields of AESoS based on HPPC.","internal_url":"https://www.academia.edu/105758743/Study_on_High_Performance_Simulation_Computer_for_Large_Scale_System_of_Systems_Simulation","translated_internal_url":"","created_at":"2023-08-19T17:55:06.010-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":24656298,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Study_on_High_Performance_Simulation_Computer_for_Large_Scale_System_of_Systems_Simulation","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":24656298,"first_name":"Jia","middle_initials":null,"last_name":"Hao","page_name":"JiaHao2","domain_name":"independent","created_at":"2015-01-11T07:08:00.159-08:00","display_name":"Jia Hao","url":"https://independent.academia.edu/JiaHao2"},"attachments":[],"research_interests":[{"id":48,"name":"Engineering","url":"https://www.academia.edu/Documents/in/Engineering"},{"id":422,"name":"Computer Science","url":"https://www.academia.edu/Documents/in/Computer_Science"},{"id":99926,"name":"System of Systems","url":"https://www.academia.edu/Documents/in/System_of_Systems"}],"urls":[{"id":33510682,"url":"http://www.scientific.net/AMM.548-549.1311.pdf"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="105758742"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/105758742/Modeling_and_optimizing_inhibitory_activities_of_Nelumbinis_folium_extract_on_xanthine_oxidase_using_response_surface_methodology"><img alt="Research paper thumbnail of Modeling and optimizing inhibitory activities of Nelumbinis folium extract on xanthine oxidase using response surface methodology" class="work-thumbnail" src="https://attachments.academia-assets.com/105137862/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/105758742/Modeling_and_optimizing_inhibitory_activities_of_Nelumbinis_folium_extract_on_xanthine_oxidase_using_response_surface_methodology">Modeling and optimizing inhibitory activities of Nelumbinis folium extract on xanthine oxidase using response surface methodology</a></div><div class="wp-workCard_item"><span>Journal of pharmaceutical and biomedical analysis</span><span>, 2017</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Xanthine oxidase (XOD), which could oxidize hypoxanthine to xanthine and then to uric acid, is a ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Xanthine oxidase (XOD), which could oxidize hypoxanthine to xanthine and then to uric acid, is a key enzyme in the pathogenesis of hyperuricemia and also a well-known target for the drug development to treat gout. In our study, the total alkaloids of Nelumbinis folium markedly inhibited XOD activity, with IC50 value being 3.313μg/mL. UHPLC-Q-TOF-MS and 3D docking analysis indicated that roemerine was a potential active ingredient. A response surface methodology combined with central composite design experiment was further developed and validated for the optimization of the reaction conditions between the total alkaloids of Nelumbinis folium and XOD, which could be considered as a meaningful research for the development of XOD inhibitor rapidly and sensitively.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="40342a22e5669ec72cf42e60c8712255" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":105137862,"asset_id":105758742,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/105137862/download_file?st=MTczMjczOTk3Myw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="105758742"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="105758742"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 105758742; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=105758742]").text(description); $(".js-view-count[data-work-id=105758742]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 105758742; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='105758742']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 105758742, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "40342a22e5669ec72cf42e60c8712255" } } $('.js-work-strip[data-work-id=105758742]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":105758742,"title":"Modeling and optimizing inhibitory activities of Nelumbinis folium extract on xanthine oxidase using response surface methodology","translated_title":"","metadata":{"abstract":"Xanthine oxidase (XOD), which could oxidize hypoxanthine to xanthine and then to uric acid, is a key enzyme in the pathogenesis of hyperuricemia and also a well-known target for the drug development to treat gout. In our study, the total alkaloids of Nelumbinis folium markedly inhibited XOD activity, with IC50 value being 3.313μg/mL. UHPLC-Q-TOF-MS and 3D docking analysis indicated that roemerine was a potential active ingredient. A response surface methodology combined with central composite design experiment was further developed and validated for the optimization of the reaction conditions between the total alkaloids of Nelumbinis folium and XOD, which could be considered as a meaningful research for the development of XOD inhibitor rapidly and sensitively.","ai_title_tag":"Optimizing Nelumbinis Folium Extract as Xanthine Oxidase Inhibitor","publication_date":{"day":null,"month":null,"year":2017,"errors":{}},"publication_name":"Journal of pharmaceutical and biomedical analysis"},"translated_abstract":"Xanthine oxidase (XOD), which could oxidize hypoxanthine to xanthine and then to uric acid, is a key enzyme in the pathogenesis of hyperuricemia and also a well-known target for the drug development to treat gout. In our study, the total alkaloids of Nelumbinis folium markedly inhibited XOD activity, with IC50 value being 3.313μg/mL. UHPLC-Q-TOF-MS and 3D docking analysis indicated that roemerine was a potential active ingredient. A response surface methodology combined with central composite design experiment was further developed and validated for the optimization of the reaction conditions between the total alkaloids of Nelumbinis folium and XOD, which could be considered as a meaningful research for the development of XOD inhibitor rapidly and sensitively.","internal_url":"https://www.academia.edu/105758742/Modeling_and_optimizing_inhibitory_activities_of_Nelumbinis_folium_extract_on_xanthine_oxidase_using_response_surface_methodology","translated_internal_url":"","created_at":"2023-08-19T17:55:05.814-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":24656298,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":105137862,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/105137862/thumbnails/1.jpg","file_name":"j.jpba.2017.02.04820230820-1-fkdkrm.pdf","download_url":"https://www.academia.edu/attachments/105137862/download_file?st=MTczMjczOTk3Myw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Modeling_and_optimizing_inhibitory_activ.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/105137862/j.jpba.2017.02.04820230820-1-fkdkrm-libre.pdf?1692497783=\u0026response-content-disposition=attachment%3B+filename%3DModeling_and_optimizing_inhibitory_activ.pdf\u0026Expires=1732743573\u0026Signature=LFy1tceDndWtxGDow0t4NEyTK6POxdxP3VlGRbOC8oSFi3LoQD9xSf3m9wrLRusFfADie3qB0m8iBUeFhb6Wq7vtyQYaIf2TMidLEp8fYPnABlGL304DpMjtqTzy6-rjZ7r3yaYpxpw7TVpVw3v8Hi5~smaQLPZmfdqXjakMAG~LxMz2nrvp0OZ45AUe9VvCUFdaRa~HC646vPLNoW7n~rD7JyIrKYKF2CoGGzp0116tI8Gnqn8BucxMCNPhadCDBEUawKAmqEoOWn8r4ZbdmCcyFmCS9TLgbExgjIFRPyVgoPeL1rLKTHcuOMALl7zHNssG0IlpeXDmJ-oytAf7BA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Modeling_and_optimizing_inhibitory_activities_of_Nelumbinis_folium_extract_on_xanthine_oxidase_using_response_surface_methodology","translated_slug":"","page_count":20,"language":"en","content_type":"Work","owner":{"id":24656298,"first_name":"Jia","middle_initials":null,"last_name":"Hao","page_name":"JiaHao2","domain_name":"independent","created_at":"2015-01-11T07:08:00.159-08:00","display_name":"Jia Hao","url":"https://independent.academia.edu/JiaHao2"},"attachments":[{"id":105137862,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/105137862/thumbnails/1.jpg","file_name":"j.jpba.2017.02.04820230820-1-fkdkrm.pdf","download_url":"https://www.academia.edu/attachments/105137862/download_file?st=MTczMjczOTk3Myw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Modeling_and_optimizing_inhibitory_activ.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/105137862/j.jpba.2017.02.04820230820-1-fkdkrm-libre.pdf?1692497783=\u0026response-content-disposition=attachment%3B+filename%3DModeling_and_optimizing_inhibitory_activ.pdf\u0026Expires=1732743573\u0026Signature=LFy1tceDndWtxGDow0t4NEyTK6POxdxP3VlGRbOC8oSFi3LoQD9xSf3m9wrLRusFfADie3qB0m8iBUeFhb6Wq7vtyQYaIf2TMidLEp8fYPnABlGL304DpMjtqTzy6-rjZ7r3yaYpxpw7TVpVw3v8Hi5~smaQLPZmfdqXjakMAG~LxMz2nrvp0OZ45AUe9VvCUFdaRa~HC646vPLNoW7n~rD7JyIrKYKF2CoGGzp0116tI8Gnqn8BucxMCNPhadCDBEUawKAmqEoOWn8r4ZbdmCcyFmCS9TLgbExgjIFRPyVgoPeL1rLKTHcuOMALl7zHNssG0IlpeXDmJ-oytAf7BA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":140,"name":"Pharmacology","url":"https://www.academia.edu/Documents/in/Pharmacology"},{"id":523,"name":"Chemistry","url":"https://www.academia.edu/Documents/in/Chemistry"},{"id":524,"name":"Analytical Chemistry","url":"https://www.academia.edu/Documents/in/Analytical_Chemistry"},{"id":9508,"name":"Response Surface Methodology","url":"https://www.academia.edu/Documents/in/Response_Surface_Methodology"},{"id":12981,"name":"Enzyme Inhibitors","url":"https://www.academia.edu/Documents/in/Enzyme_Inhibitors"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":62970,"name":"Nelumbo","url":"https://www.academia.edu/Documents/in/Nelumbo"},{"id":102739,"name":"Ic","url":"https://www.academia.edu/Documents/in/Ic"},{"id":227305,"name":"Hyperuricemia","url":"https://www.academia.edu/Documents/in/Hyperuricemia"},{"id":309088,"name":"Uric Acid","url":"https://www.academia.edu/Documents/in/Uric_Acid"},{"id":354056,"name":"Plant extracts","url":"https://www.academia.edu/Documents/in/Plant_extracts"},{"id":1546570,"name":"Xanthine Oxidase","url":"https://www.academia.edu/Documents/in/Xanthine_Oxidase"},{"id":1905343,"name":"Plant Leaves","url":"https://www.academia.edu/Documents/in/Plant_Leaves"},{"id":3789884,"name":"Pharmacology and pharmaceutical sciences","url":"https://www.academia.edu/Documents/in/Pharmacology_and_pharmaceutical_sciences"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="105758741"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/105758741/Ligature_induced_peri_implantitis_tissue_destruction_and_inflammatory_progression_in_a_murine_model"><img alt="Research paper thumbnail of Ligature induced peri-implantitis: tissue destruction and inflammatory progression in a murine model" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/105758741/Ligature_induced_peri_implantitis_tissue_destruction_and_inflammatory_progression_in_a_murine_model">Ligature induced peri-implantitis: tissue destruction and inflammatory progression in a murine model</a></div><div class="wp-workCard_item"><span>Clinical Oral Implants Research</span><span>, 2016</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The aim of this study was to investigate tissue destruction and inflammatory progression of ligat...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The aim of this study was to investigate tissue destruction and inflammatory progression of ligature-induced peri-implantitis in mice and to establish an alternative murine model of peri-implantitis. Sixty male C57BL/6NCrSlc mice (4-week-old) were used and the maxillary right first molars were extracted. Eight weeks after extraction, custom-made pure titanium machined screw type implants (0.8 × 1.5 mm) were placed, one implant per animal. Four weeks later, 5-0 silk ligatures were applied around implant necks to induce peri-implantitis. Animals were sacrificed at 0 (before ligature), 7, 14, 21 and 28 days after ligature. Half of the samples were analyzed radiologically and histologically to measure bone level change, osteoclast number, density, and distribution. The rest of the samples was used to determine the relative mRNA expression levels of IL-1 and TNF-α with RT-PCR analysis. Bone levels at all sites (buccal, palatal, mesial, distal) decreased 40-50% significantly 28 days after ligature (P &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.01). Osteoclast number at all post-ligature time points increased significantly (P &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.05). However, their density at day 28 decreased significantly compared to that of day 21 (P &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.05). Accordingly, IL-1 and TNF-α mRNA expression increased significantly at the early time points but decreased significantly at day 28 after ligature (P &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.05). Inflammatory response followed by significant peri-implant bone resorption suggested 28 days ligation is sufficient to successfully induce peri-implantitis in the current mice model. This model might open a new avenue to study the pathogenesis and mechanism of peri-implantitis.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="105758741"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="105758741"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 105758741; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=105758741]").text(description); $(".js-view-count[data-work-id=105758741]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 105758741; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='105758741']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 105758741, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=105758741]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":105758741,"title":"Ligature induced peri-implantitis: tissue destruction and inflammatory progression in a murine model","translated_title":"","metadata":{"abstract":"The aim of this study was to investigate tissue destruction and inflammatory progression of ligature-induced peri-implantitis in mice and to establish an alternative murine model of peri-implantitis. Sixty male C57BL/6NCrSlc mice (4-week-old) were used and the maxillary right first molars were extracted. Eight weeks after extraction, custom-made pure titanium machined screw type implants (0.8 × 1.5 mm) were placed, one implant per animal. Four weeks later, 5-0 silk ligatures were applied around implant necks to induce peri-implantitis. Animals were sacrificed at 0 (before ligature), 7, 14, 21 and 28 days after ligature. Half of the samples were analyzed radiologically and histologically to measure bone level change, osteoclast number, density, and distribution. The rest of the samples was used to determine the relative mRNA expression levels of IL-1 and TNF-α with RT-PCR analysis. Bone levels at all sites (buccal, palatal, mesial, distal) decreased 40-50% significantly 28 days after ligature (P \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.01). Osteoclast number at all post-ligature time points increased significantly (P \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.05). However, their density at day 28 decreased significantly compared to that of day 21 (P \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.05). Accordingly, IL-1 and TNF-α mRNA expression increased significantly at the early time points but decreased significantly at day 28 after ligature (P \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.05). Inflammatory response followed by significant peri-implant bone resorption suggested 28 days ligation is sufficient to successfully induce peri-implantitis in the current mice model. This model might open a new avenue to study the pathogenesis and mechanism of peri-implantitis.","publisher":"Wiley","publication_date":{"day":null,"month":null,"year":2016,"errors":{}},"publication_name":"Clinical Oral Implants Research"},"translated_abstract":"The aim of this study was to investigate tissue destruction and inflammatory progression of ligature-induced peri-implantitis in mice and to establish an alternative murine model of peri-implantitis. Sixty male C57BL/6NCrSlc mice (4-week-old) were used and the maxillary right first molars were extracted. Eight weeks after extraction, custom-made pure titanium machined screw type implants (0.8 × 1.5 mm) were placed, one implant per animal. Four weeks later, 5-0 silk ligatures were applied around implant necks to induce peri-implantitis. Animals were sacrificed at 0 (before ligature), 7, 14, 21 and 28 days after ligature. Half of the samples were analyzed radiologically and histologically to measure bone level change, osteoclast number, density, and distribution. The rest of the samples was used to determine the relative mRNA expression levels of IL-1 and TNF-α with RT-PCR analysis. Bone levels at all sites (buccal, palatal, mesial, distal) decreased 40-50% significantly 28 days after ligature (P \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.01). Osteoclast number at all post-ligature time points increased significantly (P \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.05). However, their density at day 28 decreased significantly compared to that of day 21 (P \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.05). Accordingly, IL-1 and TNF-α mRNA expression increased significantly at the early time points but decreased significantly at day 28 after ligature (P \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.05). Inflammatory response followed by significant peri-implant bone resorption suggested 28 days ligation is sufficient to successfully induce peri-implantitis in the current mice model. This model might open a new avenue to study the pathogenesis and mechanism of peri-implantitis.","internal_url":"https://www.academia.edu/105758741/Ligature_induced_peri_implantitis_tissue_destruction_and_inflammatory_progression_in_a_murine_model","translated_internal_url":"","created_at":"2023-08-19T17:55:05.593-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":24656298,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Ligature_induced_peri_implantitis_tissue_destruction_and_inflammatory_progression_in_a_murine_model","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":24656298,"first_name":"Jia","middle_initials":null,"last_name":"Hao","page_name":"JiaHao2","domain_name":"independent","created_at":"2015-01-11T07:08:00.159-08:00","display_name":"Jia Hao","url":"https://independent.academia.edu/JiaHao2"},"attachments":[],"research_interests":[{"id":596,"name":"Dentistry","url":"https://www.academia.edu/Documents/in/Dentistry"},{"id":1131,"name":"Biomedical Engineering","url":"https://www.academia.edu/Documents/in/Biomedical_Engineering"},{"id":6970,"name":"Biomarkers","url":"https://www.academia.edu/Documents/in/Biomarkers"},{"id":9334,"name":"Inflammation","url":"https://www.academia.edu/Documents/in/Inflammation"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":84760,"name":"Mice","url":"https://www.academia.edu/Documents/in/Mice"},{"id":185112,"name":"Maxilla","url":"https://www.academia.edu/Documents/in/Maxilla"},{"id":407481,"name":"Implant","url":"https://www.academia.edu/Documents/in/Implant"},{"id":474029,"name":"Tumor necrosis factor-alpha","url":"https://www.academia.edu/Documents/in/Tumor_necrosis_factor-alpha"},{"id":584615,"name":"Disease Progression","url":"https://www.academia.edu/Documents/in/Disease_Progression"},{"id":1027671,"name":"Resorption","url":"https://www.academia.edu/Documents/in/Resorption"},{"id":1238472,"name":"Peri-implantitis","url":"https://www.academia.edu/Documents/in/Peri-implantitis"},{"id":1399820,"name":"Bone Resorption","url":"https://www.academia.edu/Documents/in/Bone_Resorption"},{"id":1924712,"name":"Interleukin","url":"https://www.academia.edu/Documents/in/Interleukin"},{"id":2940273,"name":"real time polymerase chain reaction","url":"https://www.academia.edu/Documents/in/real_time_polymerase_chain_reaction"},{"id":3197061,"name":"Molar","url":"https://www.academia.edu/Documents/in/Molar"},{"id":3589281,"name":"Ligation","url":"https://www.academia.edu/Documents/in/Ligation"}],"urls":[{"id":33510681,"url":"http://onlinelibrary.wiley.com/wol1/doi/10.1111/clr.12770/fullpdf"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="105758740"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/105758740/Towards_dose_reduction_for_dual_energy_CT_A_non_local_image_improvement_method_and_its_application"><img alt="Research paper thumbnail of Towards dose reduction for dual-energy CT: A non-local image improvement method and its application" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/105758740/Towards_dose_reduction_for_dual_energy_CT_A_non_local_image_improvement_method_and_its_application">Towards dose reduction for dual-energy CT: A non-local image improvement method and its application</a></div><div class="wp-workCard_item"><span>Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment</span><span>, 2015</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">ABSTRACT Dual-energy CT (DECT) has better material discrimination capability than single-energy C...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">ABSTRACT Dual-energy CT (DECT) has better material discrimination capability than single-energy CT. In this paper, we propose a low-dose DECT scanning strategy with double scans under different energy spectra. In the strategy a low-energy scan is performed with a complete number of views, and the high-energy scan is in much sparser views to reduce radiation dose. In such conditions, the high-energy reconstruction image suffers from severe streak artifacts due to under-sampling. To address this problem a novel non-local image restoration method is proposed. Because the low and high energy scans are performed on the same object, the reconstructed images should have identical object structures. Therefore the low-energy reconstruction that comes from the complete scan may serve as a reference image to help improving the image quality of the high-energy reconstruction. The method is implemented with the following steps. First, the structure information is obtained by a non-local pixel similarity measurement on the low-energy CT image, and second after a registration between the high and low reconstructions the high-energy image is restored by normalized weighted average using the calculated similarity relationship. Compared with previous methods, the new method achieves better image quality in both structure preservation and artifact reduction. Besides, the computation is much cheaper than iterative reconstruction methods, which makes the method of practical value. Numerical and pre-clinical experiments have been performed to illustrate the effectiveness of the proposed method. With the novel DECT scanning configuration and non-local image restoration method, the total dose is significantly reduced while maintaining a high reconstruction quality.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="105758740"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="105758740"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 105758740; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=105758740]").text(description); $(".js-view-count[data-work-id=105758740]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 105758740; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='105758740']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 105758740, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=105758740]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":105758740,"title":"Towards dose reduction for dual-energy CT: A non-local image improvement method and its application","translated_title":"","metadata":{"abstract":"ABSTRACT Dual-energy CT (DECT) has better material discrimination capability than single-energy CT. In this paper, we propose a low-dose DECT scanning strategy with double scans under different energy spectra. In the strategy a low-energy scan is performed with a complete number of views, and the high-energy scan is in much sparser views to reduce radiation dose. In such conditions, the high-energy reconstruction image suffers from severe streak artifacts due to under-sampling. To address this problem a novel non-local image restoration method is proposed. Because the low and high energy scans are performed on the same object, the reconstructed images should have identical object structures. Therefore the low-energy reconstruction that comes from the complete scan may serve as a reference image to help improving the image quality of the high-energy reconstruction. The method is implemented with the following steps. First, the structure information is obtained by a non-local pixel similarity measurement on the low-energy CT image, and second after a registration between the high and low reconstructions the high-energy image is restored by normalized weighted average using the calculated similarity relationship. Compared with previous methods, the new method achieves better image quality in both structure preservation and artifact reduction. Besides, the computation is much cheaper than iterative reconstruction methods, which makes the method of practical value. Numerical and pre-clinical experiments have been performed to illustrate the effectiveness of the proposed method. With the novel DECT scanning configuration and non-local image restoration method, the total dose is significantly reduced while maintaining a high reconstruction quality.","publisher":"Elsevier BV","publication_date":{"day":null,"month":null,"year":2015,"errors":{}},"publication_name":"Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment"},"translated_abstract":"ABSTRACT Dual-energy CT (DECT) has better material discrimination capability than single-energy CT. In this paper, we propose a low-dose DECT scanning strategy with double scans under different energy spectra. In the strategy a low-energy scan is performed with a complete number of views, and the high-energy scan is in much sparser views to reduce radiation dose. In such conditions, the high-energy reconstruction image suffers from severe streak artifacts due to under-sampling. To address this problem a novel non-local image restoration method is proposed. Because the low and high energy scans are performed on the same object, the reconstructed images should have identical object structures. Therefore the low-energy reconstruction that comes from the complete scan may serve as a reference image to help improving the image quality of the high-energy reconstruction. The method is implemented with the following steps. First, the structure information is obtained by a non-local pixel similarity measurement on the low-energy CT image, and second after a registration between the high and low reconstructions the high-energy image is restored by normalized weighted average using the calculated similarity relationship. Compared with previous methods, the new method achieves better image quality in both structure preservation and artifact reduction. Besides, the computation is much cheaper than iterative reconstruction methods, which makes the method of practical value. Numerical and pre-clinical experiments have been performed to illustrate the effectiveness of the proposed method. With the novel DECT scanning configuration and non-local image restoration method, the total dose is significantly reduced while maintaining a high reconstruction quality.","internal_url":"https://www.academia.edu/105758740/Towards_dose_reduction_for_dual_energy_CT_A_non_local_image_improvement_method_and_its_application","translated_internal_url":"","created_at":"2023-08-19T17:55:05.424-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":24656298,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Towards_dose_reduction_for_dual_energy_CT_A_non_local_image_improvement_method_and_its_application","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":24656298,"first_name":"Jia","middle_initials":null,"last_name":"Hao","page_name":"JiaHao2","domain_name":"independent","created_at":"2015-01-11T07:08:00.159-08:00","display_name":"Jia Hao","url":"https://independent.academia.edu/JiaHao2"},"attachments":[],"research_interests":[{"id":422,"name":"Computer Science","url":"https://www.academia.edu/Documents/in/Computer_Science"},{"id":465,"name":"Artificial Intelligence","url":"https://www.academia.edu/Documents/in/Artificial_Intelligence"},{"id":498,"name":"Physics","url":"https://www.academia.edu/Documents/in/Physics"},{"id":854,"name":"Computer Vision","url":"https://www.academia.edu/Documents/in/Computer_Vision"},{"id":30415,"name":"Image Quality","url":"https://www.academia.edu/Documents/in/Image_Quality"},{"id":1707689,"name":"Pixel","url":"https://www.academia.edu/Documents/in/Pixel"},{"id":2466378,"name":"Iterative Reconstruction","url":"https://www.academia.edu/Documents/in/Iterative_Reconstruction"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="105758739"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/105758739/Does_Removing_the_Short_sale_Constraint_Improve_Liquidity_Evidence_from_Hong_Kong"><img alt="Research paper thumbnail of Does Removing the Short-sale Constraint Improve Liquidity? Evidence from Hong Kong" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/105758739/Does_Removing_the_Short_sale_Constraint_Improve_Liquidity_Evidence_from_Hong_Kong">Does Removing the Short-sale Constraint Improve Liquidity? Evidence from Hong Kong</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The short-sale regulations in Hong Kong provide a unique setting to examine the effects of short-...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The short-sale regulations in Hong Kong provide a unique setting to examine the effects of short- sale constraints on stock market liquidity. Short selling of stocks was prohibited in Hong Kong till 1994. The restrictions were relaxed over a period of eight years in our sample period. We find that removing the short-sale constraints increased the liquidity of lower priced stocks but not higher priced ones. Low priced and high priced stocks had comparable market capitalizations in Hong Kong. However, lower priced stocks had less publicly available information - they had larger adverse selection components in their bid-ask spreads and less sell-side analyst coverage. We also find that the &quot;uptick rule&quot; significantly decreases the market quality. Finally we do not find any evidence that relaxing the short-sale constraints increases total volatilities, upside volatilities, or downside volatilities.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="105758739"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="105758739"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 105758739; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=105758739]").text(description); $(".js-view-count[data-work-id=105758739]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 105758739; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='105758739']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 105758739, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=105758739]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":105758739,"title":"Does Removing the Short-sale Constraint Improve Liquidity? Evidence from Hong Kong","translated_title":"","metadata":{"abstract":"The short-sale regulations in Hong Kong provide a unique setting to examine the effects of short- sale constraints on stock market liquidity. Short selling of stocks was prohibited in Hong Kong till 1994. The restrictions were relaxed over a period of eight years in our sample period. We find that removing the short-sale constraints increased the liquidity of lower priced stocks but not higher priced ones. Low priced and high priced stocks had comparable market capitalizations in Hong Kong. However, lower priced stocks had less publicly available information - they had larger adverse selection components in their bid-ask spreads and less sell-side analyst coverage. We also find that the \u0026quot;uptick rule\u0026quot; significantly decreases the market quality. Finally we do not find any evidence that relaxing the short-sale constraints increases total volatilities, upside volatilities, or downside volatilities."},"translated_abstract":"The short-sale regulations in Hong Kong provide a unique setting to examine the effects of short- sale constraints on stock market liquidity. Short selling of stocks was prohibited in Hong Kong till 1994. The restrictions were relaxed over a period of eight years in our sample period. We find that removing the short-sale constraints increased the liquidity of lower priced stocks but not higher priced ones. Low priced and high priced stocks had comparable market capitalizations in Hong Kong. However, lower priced stocks had less publicly available information - they had larger adverse selection components in their bid-ask spreads and less sell-side analyst coverage. We also find that the \u0026quot;uptick rule\u0026quot; significantly decreases the market quality. Finally we do not find any evidence that relaxing the short-sale constraints increases total volatilities, upside volatilities, or downside volatilities.","internal_url":"https://www.academia.edu/105758739/Does_Removing_the_Short_sale_Constraint_Improve_Liquidity_Evidence_from_Hong_Kong","translated_internal_url":"","created_at":"2023-08-19T17:55:05.291-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":24656298,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Does_Removing_the_Short_sale_Constraint_Improve_Liquidity_Evidence_from_Hong_Kong","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":24656298,"first_name":"Jia","middle_initials":null,"last_name":"Hao","page_name":"JiaHao2","domain_name":"independent","created_at":"2015-01-11T07:08:00.159-08:00","display_name":"Jia Hao","url":"https://independent.academia.edu/JiaHao2"},"attachments":[],"research_interests":[{"id":26,"name":"Business","url":"https://www.academia.edu/Documents/in/Business"},{"id":49636,"name":"Adverse Selection","url":"https://www.academia.edu/Documents/in/Adverse_Selection"},{"id":311931,"name":"STOCK EXCHANGE","url":"https://www.academia.edu/Documents/in/STOCK_EXCHANGE"},{"id":3751233,"name":"Market Liquidity","url":"https://www.academia.edu/Documents/in/Market_Liquidity"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="105758738"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/105758738/Research_of_a_Dynamic_Frequency_Spectrum_Assignment_Algorithm_Based_on_Battle_Management_and_Control"><img alt="Research paper thumbnail of Research of a Dynamic Frequency Spectrum Assignment Algorithm Based on Battle Management and Control" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/105758738/Research_of_a_Dynamic_Frequency_Spectrum_Assignment_Algorithm_Based_on_Battle_Management_and_Control">Research of a Dynamic Frequency Spectrum Assignment Algorithm Based on Battle Management and Control</a></div><div class="wp-workCard_item"><span>2010 International Conference on Computational Intelligence and Software Engineering</span><span>, 2010</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Currently, in the military wireless communication, the battle which based on the electromagnetic ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Currently, in the military wireless communication, the battle which based on the electromagnetic environment is very complex. To make sure the army can command the informationization war successfully and win the war finally, using optimized frequency spectrum assignment technology to improve the service efficiency of frequency spectrum resource is become the hot issue in the research of frequency spectrum management domain. Based on battle management and control, in this paper the frequency spectrum assignment problem is abstracted to an assignment problem. The relevant mathematics model of frequency spectrum assignment is built in the paper. The Hungary algorithm is introduced to solve the mathematics model. At last, the logical frequency spectrum assignment scheme is obtained.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="105758738"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="105758738"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 105758738; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=105758738]").text(description); $(".js-view-count[data-work-id=105758738]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 105758738; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='105758738']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 105758738, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=105758738]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":105758738,"title":"Research of a Dynamic Frequency Spectrum Assignment Algorithm Based on Battle Management and Control","translated_title":"","metadata":{"abstract":"Currently, in the military wireless communication, the battle which based on the electromagnetic environment is very complex. To make sure the army can command the informationization war successfully and win the war finally, using optimized frequency spectrum assignment technology to improve the service efficiency of frequency spectrum resource is become the hot issue in the research of frequency spectrum management domain. Based on battle management and control, in this paper the frequency spectrum assignment problem is abstracted to an assignment problem. The relevant mathematics model of frequency spectrum assignment is built in the paper. The Hungary algorithm is introduced to solve the mathematics model. At last, the logical frequency spectrum assignment scheme is obtained.","publisher":"IEEE","publication_date":{"day":null,"month":null,"year":2010,"errors":{}},"publication_name":"2010 International Conference on Computational Intelligence and Software Engineering"},"translated_abstract":"Currently, in the military wireless communication, the battle which based on the electromagnetic environment is very complex. To make sure the army can command the informationization war successfully and win the war finally, using optimized frequency spectrum assignment technology to improve the service efficiency of frequency spectrum resource is become the hot issue in the research of frequency spectrum management domain. Based on battle management and control, in this paper the frequency spectrum assignment problem is abstracted to an assignment problem. The relevant mathematics model of frequency spectrum assignment is built in the paper. The Hungary algorithm is introduced to solve the mathematics model. At last, the logical frequency spectrum assignment scheme is obtained.","internal_url":"https://www.academia.edu/105758738/Research_of_a_Dynamic_Frequency_Spectrum_Assignment_Algorithm_Based_on_Battle_Management_and_Control","translated_internal_url":"","created_at":"2023-08-19T17:55:05.117-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":24656298,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Research_of_a_Dynamic_Frequency_Spectrum_Assignment_Algorithm_Based_on_Battle_Management_and_Control","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":24656298,"first_name":"Jia","middle_initials":null,"last_name":"Hao","page_name":"JiaHao2","domain_name":"independent","created_at":"2015-01-11T07:08:00.159-08:00","display_name":"Jia Hao","url":"https://independent.academia.edu/JiaHao2"},"attachments":[],"research_interests":[{"id":422,"name":"Computer Science","url":"https://www.academia.edu/Documents/in/Computer_Science"},{"id":98566,"name":"Wireless","url":"https://www.academia.edu/Documents/in/Wireless"},{"id":573854,"name":"FREQUENCY ASSIGNMENT","url":"https://www.academia.edu/Documents/in/FREQUENCY_ASSIGNMENT"},{"id":575847,"name":"Assignment Problem","url":"https://www.academia.edu/Documents/in/Assignment_Problem"},{"id":1625072,"name":"Frequency Domain","url":"https://www.academia.edu/Documents/in/Frequency_Domain"},{"id":1995853,"name":"Frequency allocation","url":"https://www.academia.edu/Documents/in/Frequency_allocation"},{"id":2736308,"name":"Frequency spectrum","url":"https://www.academia.edu/Documents/in/Frequency_spectrum"},{"id":3042534,"name":"battle","url":"https://www.academia.edu/Documents/in/battle"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="105758737"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/105758737/The_Patching_Methods_of_the_Bayesian_Network_Data"><img alt="Research paper thumbnail of The Patching Methods of the Bayesian Network Data" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/105758737/The_Patching_Methods_of_the_Bayesian_Network_Data">The Patching Methods of the Bayesian Network Data</a></div><div class="wp-workCard_item"><span>2009 Ninth International Conference on Hybrid Intelligent Systems</span><span>, 2009</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">In this paper, as the issue of Bayesian networks with missing data bring out a repair method of d...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">In this paper, as the issue of Bayesian networks with missing data bring out a repair method of data. This method through a score function to score all nodes, so can obtained for all states points of the Bayesian Network. This is to say all states which belong to Bayesian networks matching degrees can finalized determine the add data&amp;#39;s states. Experiments show¿this method can be learning Bayesian network structure inference or to repair data to make it a complete data it can effectively improve the utilization rate of missing data.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="105758737"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="105758737"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 105758737; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=105758737]").text(description); $(".js-view-count[data-work-id=105758737]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 105758737; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='105758737']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 105758737, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=105758737]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":105758737,"title":"The Patching Methods of the Bayesian Network Data","translated_title":"","metadata":{"abstract":"In this paper, as the issue of Bayesian networks with missing data bring out a repair method of data. This method through a score function to score all nodes, so can obtained for all states points of the Bayesian Network. This is to say all states which belong to Bayesian networks matching degrees can finalized determine the add data\u0026amp;#39;s states. Experiments show¿this method can be learning Bayesian network structure inference or to repair data to make it a complete data it can effectively improve the utilization rate of missing data.","publisher":"IEEE","publication_date":{"day":null,"month":null,"year":2009,"errors":{}},"publication_name":"2009 Ninth International Conference on Hybrid Intelligent Systems"},"translated_abstract":"In this paper, as the issue of Bayesian networks with missing data bring out a repair method of data. This method through a score function to score all nodes, so can obtained for all states points of the Bayesian Network. This is to say all states which belong to Bayesian networks matching degrees can finalized determine the add data\u0026amp;#39;s states. Experiments show¿this method can be learning Bayesian network structure inference or to repair data to make it a complete data it can effectively improve the utilization rate of missing data.","internal_url":"https://www.academia.edu/105758737/The_Patching_Methods_of_the_Bayesian_Network_Data","translated_internal_url":"","created_at":"2023-08-19T17:55:04.935-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":24656298,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"The_Patching_Methods_of_the_Bayesian_Network_Data","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":24656298,"first_name":"Jia","middle_initials":null,"last_name":"Hao","page_name":"JiaHao2","domain_name":"independent","created_at":"2015-01-11T07:08:00.159-08:00","display_name":"Jia Hao","url":"https://independent.academia.edu/JiaHao2"},"attachments":[],"research_interests":[{"id":422,"name":"Computer Science","url":"https://www.academia.edu/Documents/in/Computer_Science"},{"id":18574,"name":"Inference","url":"https://www.academia.edu/Documents/in/Inference"},{"id":121607,"name":"Missing Data","url":"https://www.academia.edu/Documents/in/Missing_Data"},{"id":274599,"name":"Bayesian Network","url":"https://www.academia.edu/Documents/in/Bayesian_Network"},{"id":1032783,"name":"Bayesian Probability","url":"https://www.academia.edu/Documents/in/Bayesian_Probability"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="105758736"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/105758736/Data_transformation_and_attribute_subset_selection_Do_they_help_make_differences_in_software_failure_prediction"><img alt="Research paper thumbnail of Data transformation and attribute subset selection: Do they help make differences in software failure prediction?" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/105758736/Data_transformation_and_attribute_subset_selection_Do_they_help_make_differences_in_software_failure_prediction">Data transformation and attribute subset selection: Do they help make differences in software failure prediction?</a></div><div class="wp-workCard_item"><span>2009 IEEE International Conference on Software Maintenance</span><span>, 2009</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Data transformation and attribute subset selection have been adopted in improving software defect...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Data transformation and attribute subset selection have been adopted in improving software defect/failure prediction methods. However, little consensus was achieved on their effectiveness. This paper reports a comparative study on these two kinds of techniques ...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="105758736"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="105758736"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 105758736; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=105758736]").text(description); $(".js-view-count[data-work-id=105758736]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 105758736; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='105758736']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 105758736, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=105758736]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":105758736,"title":"Data transformation and attribute subset selection: Do they help make differences in software failure prediction?","translated_title":"","metadata":{"abstract":"Data transformation and attribute subset selection have been adopted in improving software defect/failure prediction methods. However, little consensus was achieved on their effectiveness. This paper reports a comparative study on these two kinds of techniques ...","publication_date":{"day":null,"month":null,"year":2009,"errors":{}},"publication_name":"2009 IEEE International Conference on Software Maintenance"},"translated_abstract":"Data transformation and attribute subset selection have been adopted in improving software defect/failure prediction methods. However, little consensus was achieved on their effectiveness. This paper reports a comparative study on these two kinds of techniques ...","internal_url":"https://www.academia.edu/105758736/Data_transformation_and_attribute_subset_selection_Do_they_help_make_differences_in_software_failure_prediction","translated_internal_url":"","created_at":"2023-08-19T17:55:04.789-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":24656298,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Data_transformation_and_attribute_subset_selection_Do_they_help_make_differences_in_software_failure_prediction","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":24656298,"first_name":"Jia","middle_initials":null,"last_name":"Hao","page_name":"JiaHao2","domain_name":"independent","created_at":"2015-01-11T07:08:00.159-08:00","display_name":"Jia Hao","url":"https://independent.academia.edu/JiaHao2"},"attachments":[],"research_interests":[{"id":422,"name":"Computer Science","url":"https://www.academia.edu/Documents/in/Computer_Science"},{"id":1450,"name":"Software Maintenance","url":"https://www.academia.edu/Documents/in/Software_Maintenance"},{"id":2009,"name":"Data Mining","url":"https://www.academia.edu/Documents/in/Data_Mining"},{"id":23890,"name":"Comparative Study","url":"https://www.academia.edu/Documents/in/Comparative_Study"},{"id":45834,"name":"Open Source","url":"https://www.academia.edu/Documents/in/Open_Source"},{"id":53293,"name":"Software","url":"https://www.academia.edu/Documents/in/Software"},{"id":100455,"name":"Open Source Projects","url":"https://www.academia.edu/Documents/in/Open_Source_Projects"},{"id":172642,"name":"Data Transformation","url":"https://www.academia.edu/Documents/in/Data_Transformation"},{"id":547075,"name":"Failure Prediction","url":"https://www.academia.edu/Documents/in/Failure_Prediction"},{"id":1636729,"name":"Attribute Grammars","url":"https://www.academia.edu/Documents/in/Attribute_Grammars"},{"id":2006254,"name":"Subset Selection","url":"https://www.academia.edu/Documents/in/Subset_Selection"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="105758735"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/105758735/_Relationships_between_soil_moisture_and_needle_fall_in_Masson_pine_forests_in_acid_rain_region_of_Chongqing_Southwest_China_"><img alt="Research paper thumbnail of [Relationships between soil moisture and needle-fall in Masson pine forests in acid rain region of Chongqing, Southwest China]" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/105758735/_Relationships_between_soil_moisture_and_needle_fall_in_Masson_pine_forests_in_acid_rain_region_of_Chongqing_Southwest_China_">[Relationships between soil moisture and needle-fall in Masson pine forests in acid rain region of Chongqing, Southwest China]</a></div><div class="wp-workCard_item"><span>Ying yong sheng tai xue bao = The journal of applied ecology / Zhongguo sheng tai xue xue hui, Zhongguo ke xue yuan Shenyang ying yong sheng tai yan jiu suo zhu ban</span><span>, 2012</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">From March 2009 to November 2011, an investigation was conducted on the spatiotemporal variation ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">From March 2009 to November 2011, an investigation was conducted on the spatiotemporal variation of soil moisture and its effects on the needle-fall in Masson pine (Pinus massoniana) forests in acid rain region of Chongqing, Southeast China, with the corresponding soil moisture thresholds determined. No matter the annual precipitation was abundant, normal or less than average, the seasonal variation of soil moisture in the forests could be obviously divided into four periods, i.e., sufficient (before May), descending (from June to July), drought (from August to September), and recovering (from October to November). With increasing soil depth, the soil moisture content increased after an initial decrease, but the difference of the soil moisture content among different soil layers decreased with decreasing annual precipitation. The amount of monthly needle-fall in the forests in growth season was significantly correlated with the water storage in root zone (0-60 cm soil layer), especi...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="105758735"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="105758735"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 105758735; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=105758735]").text(description); $(".js-view-count[data-work-id=105758735]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 105758735; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='105758735']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 105758735, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=105758735]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":105758735,"title":"[Relationships between soil moisture and needle-fall in Masson pine forests in acid rain region of Chongqing, Southwest China]","translated_title":"","metadata":{"abstract":"From March 2009 to November 2011, an investigation was conducted on the spatiotemporal variation of soil moisture and its effects on the needle-fall in Masson pine (Pinus massoniana) forests in acid rain region of Chongqing, Southeast China, with the corresponding soil moisture thresholds determined. No matter the annual precipitation was abundant, normal or less than average, the seasonal variation of soil moisture in the forests could be obviously divided into four periods, i.e., sufficient (before May), descending (from June to July), drought (from August to September), and recovering (from October to November). With increasing soil depth, the soil moisture content increased after an initial decrease, but the difference of the soil moisture content among different soil layers decreased with decreasing annual precipitation. The amount of monthly needle-fall in the forests in growth season was significantly correlated with the water storage in root zone (0-60 cm soil layer), especi...","publication_date":{"day":null,"month":null,"year":2012,"errors":{}},"publication_name":"Ying yong sheng tai xue bao = The journal of applied ecology / Zhongguo sheng tai xue xue hui, Zhongguo ke xue yuan Shenyang ying yong sheng tai yan jiu suo zhu ban"},"translated_abstract":"From March 2009 to November 2011, an investigation was conducted on the spatiotemporal variation of soil moisture and its effects on the needle-fall in Masson pine (Pinus massoniana) forests in acid rain region of Chongqing, Southeast China, with the corresponding soil moisture thresholds determined. No matter the annual precipitation was abundant, normal or less than average, the seasonal variation of soil moisture in the forests could be obviously divided into four periods, i.e., sufficient (before May), descending (from June to July), drought (from August to September), and recovering (from October to November). With increasing soil depth, the soil moisture content increased after an initial decrease, but the difference of the soil moisture content among different soil layers decreased with decreasing annual precipitation. The amount of monthly needle-fall in the forests in growth season was significantly correlated with the water storage in root zone (0-60 cm soil layer), especi...","internal_url":"https://www.academia.edu/105758735/_Relationships_between_soil_moisture_and_needle_fall_in_Masson_pine_forests_in_acid_rain_region_of_Chongqing_Southwest_China_","translated_internal_url":"","created_at":"2023-08-19T17:55:04.614-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":24656298,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"_Relationships_between_soil_moisture_and_needle_fall_in_Masson_pine_forests_in_acid_rain_region_of_Chongqing_Southwest_China_","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":24656298,"first_name":"Jia","middle_initials":null,"last_name":"Hao","page_name":"JiaHao2","domain_name":"independent","created_at":"2015-01-11T07:08:00.159-08:00","display_name":"Jia Hao","url":"https://independent.academia.edu/JiaHao2"},"attachments":[],"research_interests":[{"id":402,"name":"Environmental Science","url":"https://www.academia.edu/Documents/in/Environmental_Science"},{"id":1605,"name":"Soil","url":"https://www.academia.edu/Documents/in/Soil"},{"id":2215,"name":"Water","url":"https://www.academia.edu/Documents/in/Water"},{"id":12108,"name":"China","url":"https://www.academia.edu/Documents/in/China"},{"id":26177,"name":"Acid Rain","url":"https://www.academia.edu/Documents/in/Acid_Rain"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":28120,"name":"Spatio Temporal Analysis","url":"https://www.academia.edu/Documents/in/Spatio_Temporal_Analysis"},{"id":133176,"name":"Moisture","url":"https://www.academia.edu/Documents/in/Moisture"},{"id":188993,"name":"Litter","url":"https://www.academia.edu/Documents/in/Litter"},{"id":291658,"name":"Precipitation","url":"https://www.academia.edu/Documents/in/Precipitation"},{"id":359474,"name":"Pinus","url":"https://www.academia.edu/Documents/in/Pinus"},{"id":373754,"name":"Ecosystem","url":"https://www.academia.edu/Documents/in/Ecosystem"},{"id":649451,"name":"Seasons","url":"https://www.academia.edu/Documents/in/Seasons"},{"id":845678,"name":"Water Content","url":"https://www.academia.edu/Documents/in/Water_Content"},{"id":1222799,"name":"Soil Water","url":"https://www.academia.edu/Documents/in/Soil_Water"},{"id":1905343,"name":"Plant Leaves","url":"https://www.academia.edu/Documents/in/Plant_Leaves"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="105758734"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/105758734/EF4_knockout_E_coli_cells_exhibit_lower_levels_of_cellular_biosynthesis_under_acidic_stress"><img alt="Research paper thumbnail of EF4 knockout E. coli cells exhibit lower levels of cellular biosynthesis under acidic stress" class="work-thumbnail" src="https://attachments.academia-assets.com/105137861/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/105758734/EF4_knockout_E_coli_cells_exhibit_lower_levels_of_cellular_biosynthesis_under_acidic_stress">EF4 knockout E. coli cells exhibit lower levels of cellular biosynthesis under acidic stress</a></div><div class="wp-workCard_item"><span>Protein & cell</span><span>, 2014</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="8c4cbdcb06296a5512a336721bfdd7b2" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":105137861,"asset_id":105758734,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/105137861/download_file?st=MTczMjczOTk3NCw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="105758734"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="105758734"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 105758734; 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="105758733"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/105758733/Analysis_on_Crystal_Structure_of_7%C3%85_Halloysite"><img alt="Research paper thumbnail of Analysis on Crystal Structure of 7Å-Halloysite" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/105758733/Analysis_on_Crystal_Structure_of_7%C3%85_Halloysite">Analysis on Crystal Structure of 7Å-Halloysite</a></div><div class="wp-workCard_item"><span>Advanced Materials Research</span><span>, 2011</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Precise crystal structure determination of the Halloysite is extremely challenging because Halloy...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Precise crystal structure determination of the Halloysite is extremely challenging because Halloysite naturally occurs as small cylinders and the ideal single crystal sample is unavailable. The up-to-date ICSD does not have the cystal structure data of Halloysite. With the development of computer science and technologies, the X-ray powder diffraction technologies have been commonly used in the crystal structure determination. This paper attempts to obtain the refined crystal structure of Halloysite by using the X-ray powder diffraction, on the assumption that the Halloysite and Kaolinite have a similar cystal structure, that is, the 1:1 phyllosilicates structure. The structure refinement program Rietica 2010 is used in this paper.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="105758733"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="105758733"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 105758733; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=105758733]").text(description); $(".js-view-count[data-work-id=105758733]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 105758733; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='105758733']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 105758733, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=105758733]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":105758733,"title":"Analysis on Crystal Structure of 7Å-Halloysite","translated_title":"","metadata":{"abstract":"Precise crystal structure determination of the Halloysite is extremely challenging because Halloysite naturally occurs as small cylinders and the ideal single crystal sample is unavailable. The up-to-date ICSD does not have the cystal structure data of Halloysite. With the development of computer science and technologies, the X-ray powder diffraction technologies have been commonly used in the crystal structure determination. This paper attempts to obtain the refined crystal structure of Halloysite by using the X-ray powder diffraction, on the assumption that the Halloysite and Kaolinite have a similar cystal structure, that is, the 1:1 phyllosilicates structure. The structure refinement program Rietica 2010 is used in this paper.","publisher":"Trans Tech Publications","publication_date":{"day":null,"month":null,"year":2011,"errors":{}},"publication_name":"Advanced Materials Research"},"translated_abstract":"Precise crystal structure determination of the Halloysite is extremely challenging because Halloysite naturally occurs as small cylinders and the ideal single crystal sample is unavailable. The up-to-date ICSD does not have the cystal structure data of Halloysite. With the development of computer science and technologies, the X-ray powder diffraction technologies have been commonly used in the crystal structure determination. This paper attempts to obtain the refined crystal structure of Halloysite by using the X-ray powder diffraction, on the assumption that the Halloysite and Kaolinite have a similar cystal structure, that is, the 1:1 phyllosilicates structure. The structure refinement program Rietica 2010 is used in this paper.","internal_url":"https://www.academia.edu/105758733/Analysis_on_Crystal_Structure_of_7%C3%85_Halloysite","translated_internal_url":"","created_at":"2023-08-19T17:55:04.284-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":24656298,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Analysis_on_Crystal_Structure_of_7Å_Halloysite","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":24656298,"first_name":"Jia","middle_initials":null,"last_name":"Hao","page_name":"JiaHao2","domain_name":"independent","created_at":"2015-01-11T07:08:00.159-08:00","display_name":"Jia Hao","url":"https://independent.academia.edu/JiaHao2"},"attachments":[],"research_interests":[{"id":511,"name":"Materials Science","url":"https://www.academia.edu/Documents/in/Materials_Science"},{"id":21927,"name":"Advanced Materials","url":"https://www.academia.edu/Documents/in/Advanced_Materials"},{"id":50630,"name":"Crystal structure","url":"https://www.academia.edu/Documents/in/Crystal_structure"},{"id":165106,"name":"Diffraction","url":"https://www.academia.edu/Documents/in/Diffraction"},{"id":2443168,"name":"Halloysite","url":"https://www.academia.edu/Documents/in/Halloysite"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="105758732"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/105758732/Efficient_access_to_isomeric_2_3_dihydroxy_lupanes_first_synthesis_of_alphitolic_acid"><img alt="Research paper thumbnail of Efficient access to isomeric 2,3-dihydroxy lupanes: first synthesis of alphitolic acid" class="work-thumbnail" src="https://attachments.academia-assets.com/105137875/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/105758732/Efficient_access_to_isomeric_2_3_dihydroxy_lupanes_first_synthesis_of_alphitolic_acid">Efficient access to isomeric 2,3-dihydroxy lupanes: first synthesis of alphitolic acid</a></div><div class="wp-workCard_item"><span>Tetrahedron</span><span>, 2009</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="077b881fd50d56317aa40faf93540254" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":105137875,"asset_id":105758732,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/105137875/download_file?st=MTczMjczOTk3NCw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="105758732"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="105758732"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 105758732; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=105758732]").text(description); $(".js-view-count[data-work-id=105758732]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 105758732; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='105758732']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 105758732, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "077b881fd50d56317aa40faf93540254" } } $('.js-work-strip[data-work-id=105758732]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":105758732,"title":"Efficient access to isomeric 2,3-dihydroxy lupanes: first synthesis of alphitolic acid","translated_title":"","metadata":{"publisher":"Elsevier BV","grobid_abstract":"Alphitolic acid (3) is a naturally occurring lupane type of pentacyclic triterpene, which possesses various pharmacological properties. 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The synthesized triterpenes 3-10 were evaluated for their inhibitory activity against rabbit muscle GPa (RMGPa), and some of them exhibited moderate inhibitory activity against RMGPa.","publication_date":{"day":null,"month":null,"year":2009,"errors":{}},"publication_name":"Tetrahedron","grobid_abstract_attachment_id":105137875},"translated_abstract":null,"internal_url":"https://www.academia.edu/105758732/Efficient_access_to_isomeric_2_3_dihydroxy_lupanes_first_synthesis_of_alphitolic_acid","translated_internal_url":"","created_at":"2023-08-19T17:55:04.033-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":24656298,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":105137875,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/105137875/thumbnails/1.jpg","file_name":"j.tet.2009.07.04720230820-1-mz1a59.pdf","download_url":"https://www.academia.edu/attachments/105137875/download_file?st=MTczMjczOTk3NCw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Efficient_access_to_isomeric_2_3_dihydro.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/105137875/j.tet.2009.07.04720230820-1-mz1a59-libre.pdf?1692497763=\u0026response-content-disposition=attachment%3B+filename%3DEfficient_access_to_isomeric_2_3_dihydro.pdf\u0026Expires=1732743574\u0026Signature=XK-mX-vtvR215UMN-9pby4UGoIOzgmSRFATAOJYTv2-EzqKHvOEtjkrw~A6NaJIJR9FFeqh6SoSecRCiCAIgZISqDTAt55lXDmTi3EAYTX5tWXu1dQ6Rgr938X9AGdNEzuQfOFISbSCgkUrXVP~JvWaaChx4OJHQmifen27fyrlGo6WyV52j8bhvca1qTTWx3vMlmgj56XbLNePzFQX8NIB~eY1zsCfsuUreB-LMV7~ic1j1NkqWNeiLtrTIk3AQTcT3D5hE1bHvQWOC85GyoPetPcnP76bp-5CZNCem7bsNchH3yLgh5aF0ZvOYkgxWCM9Tob20vTOgWB~eX~obrA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Efficient_access_to_isomeric_2_3_dihydroxy_lupanes_first_synthesis_of_alphitolic_acid","translated_slug":"","page_count":10,"language":"en","content_type":"Work","owner":{"id":24656298,"first_name":"Jia","middle_initials":null,"last_name":"Hao","page_name":"JiaHao2","domain_name":"independent","created_at":"2015-01-11T07:08:00.159-08:00","display_name":"Jia Hao","url":"https://independent.academia.edu/JiaHao2"},"attachments":[{"id":105137875,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/105137875/thumbnails/1.jpg","file_name":"j.tet.2009.07.04720230820-1-mz1a59.pdf","download_url":"https://www.academia.edu/attachments/105137875/download_file?st=MTczMjczOTk3NCw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Efficient_access_to_isomeric_2_3_dihydro.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/105137875/j.tet.2009.07.04720230820-1-mz1a59-libre.pdf?1692497763=\u0026response-content-disposition=attachment%3B+filename%3DEfficient_access_to_isomeric_2_3_dihydro.pdf\u0026Expires=1732743574\u0026Signature=XK-mX-vtvR215UMN-9pby4UGoIOzgmSRFATAOJYTv2-EzqKHvOEtjkrw~A6NaJIJR9FFeqh6SoSecRCiCAIgZISqDTAt55lXDmTi3EAYTX5tWXu1dQ6Rgr938X9AGdNEzuQfOFISbSCgkUrXVP~JvWaaChx4OJHQmifen27fyrlGo6WyV52j8bhvca1qTTWx3vMlmgj56XbLNePzFQX8NIB~eY1zsCfsuUreB-LMV7~ic1j1NkqWNeiLtrTIk3AQTcT3D5hE1bHvQWOC85GyoPetPcnP76bp-5CZNCem7bsNchH3yLgh5aF0ZvOYkgxWCM9Tob20vTOgWB~eX~obrA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":523,"name":"Chemistry","url":"https://www.academia.edu/Documents/in/Chemistry"},{"id":531,"name":"Organic Chemistry","url":"https://www.academia.edu/Documents/in/Organic_Chemistry"},{"id":242013,"name":"TERPENE","url":"https://www.academia.edu/Documents/in/TERPENE"},{"id":435190,"name":"Tetrahedron","url":"https://www.academia.edu/Documents/in/Tetrahedron"},{"id":1152821,"name":"Chemical Synthesis","url":"https://www.academia.edu/Documents/in/Chemical_Synthesis"},{"id":2281154,"name":"Terpenoid","url":"https://www.academia.edu/Documents/in/Terpenoid"}],"urls":[{"id":33510680,"url":"https://api.elsevier.com/content/article/PII:S0040402009011090?httpAccept=text/xml"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="105758731"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/105758731/Assessment_of_Cancer_Pain_Management_Knowledge_in_Southwest_China_A_Survey_of_259_Physicians_from_Small_City_and_County_Hospitals"><img alt="Research paper thumbnail of Assessment of Cancer Pain Management Knowledge in Southwest China: A Survey of 259 Physicians from Small City and County Hospitals" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/105758731/Assessment_of_Cancer_Pain_Management_Knowledge_in_Southwest_China_A_Survey_of_259_Physicians_from_Small_City_and_County_Hospitals">Assessment of Cancer Pain Management Knowledge in Southwest China: A Survey of 259 Physicians from Small City and County Hospitals</a></div><div class="wp-workCard_item"><span>Journal of Palliative Medicine</span><span>, 2013</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Pain management is a critical issue in the care of cancer patients in China, especially in small ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Pain management is a critical issue in the care of cancer patients in China, especially in small city and county hospitals in southwest China. The study intended to determine Chinese physicians&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;#39; competence in cancer pain management and to assess their opinions on barriers to optimal pain management. A questionnaire on pain management was given to 259 fellows after their general orientation meeting at a tertiary teaching hospital. The questionnaire was adapted from an earlier study by the Eastern Cooperative Oncology Group (ECOG). The majority of the fellows believed that 70% of cancer patients suffer pain. Nearly 90% (224/259) indicated that their training in cancer pain management was poor. The fellows stated that concern about morphine addiction was the primary reason they hesitated to prescribe opioids, and they identified inadequate assessment of cancer pain as the most significant barrier to optimal management of cancer pain. The study reflects to some extent the state of pain management in hospitals in southwest China. Medical students and physicians in China need improved pain management education.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="105758731"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="105758731"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 105758731; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=105758731]").text(description); $(".js-view-count[data-work-id=105758731]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 105758731; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='105758731']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 105758731, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=105758731]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":105758731,"title":"Assessment of Cancer Pain Management Knowledge in Southwest China: A Survey of 259 Physicians from Small City and County Hospitals","translated_title":"","metadata":{"abstract":"Pain management is a critical issue in the care of cancer patients in China, especially in small city and county hospitals in southwest China. The study intended to determine Chinese physicians\u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;#39; competence in cancer pain management and to assess their opinions on barriers to optimal pain management. A questionnaire on pain management was given to 259 fellows after their general orientation meeting at a tertiary teaching hospital. The questionnaire was adapted from an earlier study by the Eastern Cooperative Oncology Group (ECOG). The majority of the fellows believed that 70% of cancer patients suffer pain. Nearly 90% (224/259) indicated that their training in cancer pain management was poor. The fellows stated that concern about morphine addiction was the primary reason they hesitated to prescribe opioids, and they identified inadequate assessment of cancer pain as the most significant barrier to optimal management of cancer pain. The study reflects to some extent the state of pain management in hospitals in southwest China. Medical students and physicians in China need improved pain management education.","publisher":"Mary Ann Liebert Inc","publication_date":{"day":null,"month":null,"year":2013,"errors":{}},"publication_name":"Journal of Palliative Medicine"},"translated_abstract":"Pain management is a critical issue in the care of cancer patients in China, especially in small city and county hospitals in southwest China. The study intended to determine Chinese physicians\u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;#39; competence in cancer pain management and to assess their opinions on barriers to optimal pain management. A questionnaire on pain management was given to 259 fellows after their general orientation meeting at a tertiary teaching hospital. The questionnaire was adapted from an earlier study by the Eastern Cooperative Oncology Group (ECOG). The majority of the fellows believed that 70% of cancer patients suffer pain. Nearly 90% (224/259) indicated that their training in cancer pain management was poor. The fellows stated that concern about morphine addiction was the primary reason they hesitated to prescribe opioids, and they identified inadequate assessment of cancer pain as the most significant barrier to optimal management of cancer pain. The study reflects to some extent the state of pain management in hospitals in southwest China. Medical students and physicians in China need improved pain management education.","internal_url":"https://www.academia.edu/105758731/Assessment_of_Cancer_Pain_Management_Knowledge_in_Southwest_China_A_Survey_of_259_Physicians_from_Small_City_and_County_Hospitals","translated_internal_url":"","created_at":"2023-08-19T17:55:03.878-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":24656298,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Assessment_of_Cancer_Pain_Management_Knowledge_in_Southwest_China_A_Survey_of_259_Physicians_from_Small_City_and_County_Hospitals","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":24656298,"first_name":"Jia","middle_initials":null,"last_name":"Hao","page_name":"JiaHao2","domain_name":"independent","created_at":"2015-01-11T07:08:00.159-08:00","display_name":"Jia Hao","url":"https://independent.academia.edu/JiaHao2"},"attachments":[],"research_interests":[{"id":588,"name":"Nursing","url":"https://www.academia.edu/Documents/in/Nursing"},{"id":4376,"name":"Family Medicine","url":"https://www.academia.edu/Documents/in/Family_Medicine"},{"id":6021,"name":"Cancer","url":"https://www.academia.edu/Documents/in/Cancer"},{"id":12108,"name":"China","url":"https://www.academia.edu/Documents/in/China"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":28023,"name":"Palliative Medicine","url":"https://www.academia.edu/Documents/in/Palliative_Medicine"},{"id":40165,"name":"Pain Management","url":"https://www.academia.edu/Documents/in/Pain_Management"},{"id":72845,"name":"Cancer pain","url":"https://www.academia.edu/Documents/in/Cancer_pain"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences"},{"id":327850,"name":"Questionnaires","url":"https://www.academia.edu/Documents/in/Questionnaires"},{"id":410370,"name":"Public health systems and services research","url":"https://www.academia.edu/Documents/in/Public_health_systems_and_services_research-1"},{"id":469018,"name":"Neoplasms","url":"https://www.academia.edu/Documents/in/Neoplasms"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="105758730"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/105758730/Down_regulation_of_miR_106b_suppresses_the_growth_of_human_glioma_cells"><img alt="Research paper thumbnail of Down-regulation of miR-106b suppresses the growth of human glioma cells" class="work-thumbnail" src="https://attachments.academia-assets.com/105137871/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/105758730/Down_regulation_of_miR_106b_suppresses_the_growth_of_human_glioma_cells">Down-regulation of miR-106b suppresses the growth of human glioma cells</a></div><div class="wp-workCard_item"><span>Journal of Neuro-Oncology</span><span>, 2013</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="6fa4057dfc964a4555f15a4af144dbbd" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":105137871,"asset_id":105758730,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/105137871/download_file?st=MTczMjczOTk3NCw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="105758730"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="105758730"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 105758730; 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However, the precise role of each microRNAs (miRNAs) in the cluster is not yet clear. In the present study, we examined the expression of miR-106b in glioma samples and a tissue microarray by real-time PCR and in situ hybridization (ISH), respectively, finding that miR-106b is overexpressed in the majority of gliomas. Meanwhile, the expression of miR-106b was positively correlated with tumor grade (p \\ 0.05). The transfection of a miR-106b anti-sense oligonucleotide (ASON) into three human glioma cell lines (U251, LN229 and TJ905) suppressed the proliferation of these cells. Moreover, the growth of xenograft tumors in nude mice treated with miR-106b ASON was significantly impaired. A bioinformatics analysis predicted that RBL2 may be the target of miR-106b, and dual-luciferase reporter assays identified RBL2, but not RB1 or RBL1, as a target of miR-106b. 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hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/105758729/Synthesis_of_3_Deoxypentacyclic_Triterpene_Derivatives_as_Inhibitors_of_Glycogen_Phosphorylase"><img alt="Research paper thumbnail of Synthesis of 3-Deoxypentacyclic Triterpene Derivatives as Inhibitors of Glycogen Phosphorylase" class="work-thumbnail" src="https://attachments.academia-assets.com/105137880/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/105758729/Synthesis_of_3_Deoxypentacyclic_Triterpene_Derivatives_as_Inhibitors_of_Glycogen_Phosphorylase">Synthesis of 3-Deoxypentacyclic Triterpene Derivatives as Inhibitors of Glycogen Phosphorylase</a></div><div class="wp-workCard_item"><span>Journal of Natural Products</span><span>, 2009</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="bcd73e22bcd493188c0d181b3cc161a3" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":105137880,"asset_id":105758729,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/105137880/download_file?st=MTczMjczOTk3NCw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="105758729"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item 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$a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> </div><div class="profile--tab_content_container js-tab-pane tab-pane" data-section-id="12821275" id="papers"><div class="js-work-strip profile--work_container" data-work-id="105758748"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/105758748/Characterizing_the_EEG_Features_of_Inspiring_Designers_with_Functional_Terms"><img alt="Research paper thumbnail of Characterizing the EEG Features of Inspiring Designers with Functional Terms" class="work-thumbnail" src="https://attachments.academia-assets.com/105137844/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/105758748/Characterizing_the_EEG_Features_of_Inspiring_Designers_with_Functional_Terms">Characterizing the EEG Features of Inspiring Designers with Functional Terms</a></div><div class="wp-workCard_item"><span>Human-Computer Interaction. Theories, Methods, and Human Issues</span><span>, 2018</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="8121a82edc06e2360a8ce5bc82ee2689" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":105137844,"asset_id":105758748,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/105137844/download_file?st=MTczMjczOTk3NCw4LjIyMi4yMDguMTQ2&st=MTczMjczOTk3Myw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="105758748"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="105758748"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 105758748; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=105758748]").text(description); $(".js-view-count[data-work-id=105758748]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 105758748; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='105758748']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 105758748, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "8121a82edc06e2360a8ce5bc82ee2689" } } $('.js-work-strip[data-work-id=105758748]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":105758748,"title":"Characterizing the EEG Features of Inspiring Designers with Functional Terms","translated_title":"","metadata":{"publisher":"Springer International Publishing","grobid_abstract":"This paper constructed an inspiring database containing functional terms, which was taken as the source of external stimuli provided to designers. We obtained EEG of two groups of designers based on design experiment. One group is provided with closely related functional terms, while another group is provided without stimuli. After processing these EEG, we found that there are different characteristics in the EEG for the two groups of designers. Our experimental results provide a basis for the study of design thinking using EEG.","publication_date":{"day":null,"month":null,"year":2018,"errors":{}},"publication_name":"Human-Computer Interaction. 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="105758747"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/105758747/Design_optimization_by_integrating_limited_simulation_data_and_shape_engineering_knowledge_with_Bayesian_optimization_BO_DK4DO_"><img alt="Research paper thumbnail of Design optimization by integrating limited simulation data and shape engineering knowledge with Bayesian optimization (BO-DK4DO)" class="work-thumbnail" src="https://attachments.academia-assets.com/105137864/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/105758747/Design_optimization_by_integrating_limited_simulation_data_and_shape_engineering_knowledge_with_Bayesian_optimization_BO_DK4DO_">Design optimization by integrating limited simulation data and shape engineering knowledge with Bayesian optimization (BO-DK4DO)</a></div><div class="wp-workCard_item"><span>Journal of Intelligent Manufacturing</span><span>, 2020</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="ca0d613ada4778b047f312fa3040be57" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":105137864,"asset_id":105758747,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/105137864/download_file?st=MTczMjczOTk3NCw4LjIyMi4yMDguMTQ2&st=MTczMjczOTk3Myw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="105758747"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="105758747"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 105758747; 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dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "ca0d613ada4778b047f312fa3040be57" } } $('.js-work-strip[data-work-id=105758747]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":105758747,"title":"Design optimization by integrating limited simulation data and shape engineering knowledge with Bayesian optimization (BO-DK4DO)","translated_title":"","metadata":{"publisher":"Springer Science and Business Media LLC","grobid_abstract":"Surrogate models have been widely studied for optimization tasks in the domain of engineering design. However, the expensive and time-consuming simulation cycles needed for complex products always result in limited simulation data, which brings a challenge for building high accuracy surrogate models because of the incomplete information contained in the limited simulation data. Therefore, a method that builds a surrogate model and conducts design optimization by integrating limited simulation data and engineering knowledge through Bayesian optimization (BO-DK4DO) is presented. In this method, the shape engineering knowledge is considered and used as derivative information which is integrated with the limited simulation data with a Gaussian process (GP). Then the GP is updated sequentially by sampling new simulation data and the optimal design solutions are found by maximizing the GP. The aim of BO-DK4DO is to significantly reduce the required number of computer simulations for finding optimal design solutions. The BO-DK4DO is verified by using benchmark functions and an engineering design problem: hot rod rolling. In all scenarios, the BO-DK4DO shows faster convergence rate than the general Bayesian optimization without integrating engineering knowledge, which means the required amount of data is decreased.","publication_date":{"day":null,"month":null,"year":2020,"errors":{}},"publication_name":"Journal of Intelligent Manufacturing","grobid_abstract_attachment_id":105137864},"translated_abstract":null,"internal_url":"https://www.academia.edu/105758747/Design_optimization_by_integrating_limited_simulation_data_and_shape_engineering_knowledge_with_Bayesian_optimization_BO_DK4DO_","translated_internal_url":"","created_at":"2023-08-19T17:55:07.465-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":24656298,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":105137864,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/105137864/thumbnails/1.jpg","file_name":"s10845-020-01551-820230820-1-qh8944.pdf","download_url":"https://www.academia.edu/attachments/105137864/download_file?st=MTczMjczOTk3NCw4LjIyMi4yMDguMTQ2&st=MTczMjczOTk3Myw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Design_optimization_by_integrating_limit.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/105137864/s10845-020-01551-820230820-1-qh8944-libre.pdf?1692497769=\u0026response-content-disposition=attachment%3B+filename%3DDesign_optimization_by_integrating_limit.pdf\u0026Expires=1732743573\u0026Signature=Y9zRsQktUCl2rFoG6WWKbzkB9FHAHTMw5pDpt0q-bN6WlBpEdJShmPmN-7fof~Winyw4Ayzc2v4s0ijKozRFCQ4jeLn-xjETabDpC1fF4EnXtWAHMh~UkogXTlxtBvlnAZvzFfqjjGLXdRXxAhs5WnuPeouWmcA3iCXb-WAGtIhWE~xFvqAeNhftVQvxmi-QDF9pL4pnxJVqbd1J35HqMxehhsFVZHslQ8YCpSHsjd1fsCl-mXQGQ9CqHFBaU9UISUF-3l1YdamJbRwRU5ryWMVvf7T7yLhueuHfZhka0ddeCc0pZfS70sK9ncLzegdPOHMtDB1WhRHskILuFJYE7A__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Design_optimization_by_integrating_limited_simulation_data_and_shape_engineering_knowledge_with_Bayesian_optimization_BO_DK4DO_","translated_slug":"","page_count":19,"language":"en","content_type":"Work","owner":{"id":24656298,"first_name":"Jia","middle_initials":null,"last_name":"Hao","page_name":"JiaHao2","domain_name":"independent","created_at":"2015-01-11T07:08:00.159-08:00","display_name":"Jia Hao","url":"https://independent.academia.edu/JiaHao2"},"attachments":[{"id":105137864,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/105137864/thumbnails/1.jpg","file_name":"s10845-020-01551-820230820-1-qh8944.pdf","download_url":"https://www.academia.edu/attachments/105137864/download_file?st=MTczMjczOTk3NCw4LjIyMi4yMDguMTQ2&st=MTczMjczOTk3Myw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Design_optimization_by_integrating_limit.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/105137864/s10845-020-01551-820230820-1-qh8944-libre.pdf?1692497769=\u0026response-content-disposition=attachment%3B+filename%3DDesign_optimization_by_integrating_limit.pdf\u0026Expires=1732743573\u0026Signature=Y9zRsQktUCl2rFoG6WWKbzkB9FHAHTMw5pDpt0q-bN6WlBpEdJShmPmN-7fof~Winyw4Ayzc2v4s0ijKozRFCQ4jeLn-xjETabDpC1fF4EnXtWAHMh~UkogXTlxtBvlnAZvzFfqjjGLXdRXxAhs5WnuPeouWmcA3iCXb-WAGtIhWE~xFvqAeNhftVQvxmi-QDF9pL4pnxJVqbd1J35HqMxehhsFVZHslQ8YCpSHsjd1fsCl-mXQGQ9CqHFBaU9UISUF-3l1YdamJbRwRU5ryWMVvf7T7yLhueuHfZhka0ddeCc0pZfS70sK9ncLzegdPOHMtDB1WhRHskILuFJYE7A__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":422,"name":"Computer Science","url":"https://www.academia.edu/Documents/in/Computer_Science"},{"id":46604,"name":"Intelligent Manufacturing","url":"https://www.academia.edu/Documents/in/Intelligent_Manufacturing"},{"id":55523,"name":"Engineering Optimization","url":"https://www.academia.edu/Documents/in/Engineering_Optimization"},{"id":96825,"name":"Manufacturing Engineering","url":"https://www.academia.edu/Documents/in/Manufacturing_Engineering"},{"id":535039,"name":"Bayesian Optimization","url":"https://www.academia.edu/Documents/in/Bayesian_Optimization"}],"urls":[{"id":33510685,"url":"http://link.springer.com/content/pdf/10.1007/s10845-020-01551-8.pdf"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="105758746"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/105758746/Simultaneous_determination_of_columbianetin_%CE%B2_d_glucopyranoside_and_columbianetin_in_a_biological_sample_by_high_performance_liquid_chromatography_with_fluorescence_detection_and_identification_of_other_columbianetin_%CE%B2_d_glucopyranoside_metabolites_by_ultra_high_performance_liquid_chromatography_"><img alt="Research paper thumbnail of Simultaneous determination of columbianetin-β-d-glucopyranoside and columbianetin in a biological sample by high-performance liquid chromatography with fluorescence detection and identification of other columbianetin-β-d-glucopyranoside metabolites by ultra high-performance liquid chromatography ..." class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/105758746/Simultaneous_determination_of_columbianetin_%CE%B2_d_glucopyranoside_and_columbianetin_in_a_biological_sample_by_high_performance_liquid_chromatography_with_fluorescence_detection_and_identification_of_other_columbianetin_%CE%B2_d_glucopyranoside_metabolites_by_ultra_high_performance_liquid_chromatography_">Simultaneous determination of columbianetin-β-d-glucopyranoside and columbianetin in a biological sample by high-performance liquid chromatography with fluorescence detection and identification of other columbianetin-β-d-glucopyranoside metabolites by ultra high-performance liquid chromatography ...</a></div><div class="wp-workCard_item"><span>Journal of pharmaceutical and biomedical analysis</span><span>, Jan 10, 2018</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Columbianetin-β-d-glucopyranoside (CBG) and its metabolite columbianetin (CBN) are the bioactive ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Columbianetin-β-d-glucopyranoside (CBG) and its metabolite columbianetin (CBN) are the bioactive constituents of Angelicae pubescentis radix (APR). They exhibit the anti-platelet aggregation, anti-inflammatory and analgesic properties. The absorption, distribution, metabolism and excretion (ADME) of CBG has not been reported to date. Both high-performance liquid chromatography with fluorescence detection and ultra high-performance liquid chromatography coupled with quadrupole-time-of-flight mass spectrometry methods were developed and validated for the study of ADME of CBG. It was found that CBG could be catabolized into its active metabolite CBN in vivo. The absolute bioavailability of columbianetin-β-d-glucopyranoside was 5.63 ± 4.42%. The other co-existing constituents from the APR ethanol extract could enhance the absorption of CBG. CBG and CBN were rapidly and broadly distributed in the stomach, ovary, kidney, liver, spleen, lung, muscles, heart and brain. Higher levels of accu...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="105758746"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="105758746"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 105758746; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=105758746]").text(description); $(".js-view-count[data-work-id=105758746]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 105758746; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='105758746']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 105758746, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=105758746]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":105758746,"title":"Simultaneous determination of columbianetin-β-d-glucopyranoside and columbianetin in a biological sample by high-performance liquid chromatography with fluorescence detection and identification of other columbianetin-β-d-glucopyranoside metabolites by ultra high-performance liquid chromatography ...","translated_title":"","metadata":{"abstract":"Columbianetin-β-d-glucopyranoside (CBG) and its metabolite columbianetin (CBN) are the bioactive constituents of Angelicae pubescentis radix (APR). They exhibit the anti-platelet aggregation, anti-inflammatory and analgesic properties. The absorption, distribution, metabolism and excretion (ADME) of CBG has not been reported to date. Both high-performance liquid chromatography with fluorescence detection and ultra high-performance liquid chromatography coupled with quadrupole-time-of-flight mass spectrometry methods were developed and validated for the study of ADME of CBG. It was found that CBG could be catabolized into its active metabolite CBN in vivo. The absolute bioavailability of columbianetin-β-d-glucopyranoside was 5.63 ± 4.42%. The other co-existing constituents from the APR ethanol extract could enhance the absorption of CBG. CBG and CBN were rapidly and broadly distributed in the stomach, ovary, kidney, liver, spleen, lung, muscles, heart and brain. Higher levels of accu...","publication_date":{"day":10,"month":1,"year":2018,"errors":{}},"publication_name":"Journal of pharmaceutical and biomedical analysis"},"translated_abstract":"Columbianetin-β-d-glucopyranoside (CBG) and its metabolite columbianetin (CBN) are the bioactive constituents of Angelicae pubescentis radix (APR). They exhibit the anti-platelet aggregation, anti-inflammatory and analgesic properties. The absorption, distribution, metabolism and excretion (ADME) of CBG has not been reported to date. Both high-performance liquid chromatography with fluorescence detection and ultra high-performance liquid chromatography coupled with quadrupole-time-of-flight mass spectrometry methods were developed and validated for the study of ADME of CBG. It was found that CBG could be catabolized into its active metabolite CBN in vivo. The absolute bioavailability of columbianetin-β-d-glucopyranoside was 5.63 ± 4.42%. The other co-existing constituents from the APR ethanol extract could enhance the absorption of CBG. CBG and CBN were rapidly and broadly distributed in the stomach, ovary, kidney, liver, spleen, lung, muscles, heart and brain. Higher levels of accu...","internal_url":"https://www.academia.edu/105758746/Simultaneous_determination_of_columbianetin_%CE%B2_d_glucopyranoside_and_columbianetin_in_a_biological_sample_by_high_performance_liquid_chromatography_with_fluorescence_detection_and_identification_of_other_columbianetin_%CE%B2_d_glucopyranoside_metabolites_by_ultra_high_performance_liquid_chromatography_","translated_internal_url":"","created_at":"2023-08-19T17:55:07.268-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":24656298,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Simultaneous_determination_of_columbianetin_β_d_glucopyranoside_and_columbianetin_in_a_biological_sample_by_high_performance_liquid_chromatography_with_fluorescence_detection_and_identification_of_other_columbianetin_β_d_glucopyranoside_metabolites_by_ultra_high_performance_liquid_chromatography_","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":24656298,"first_name":"Jia","middle_initials":null,"last_name":"Hao","page_name":"JiaHao2","domain_name":"independent","created_at":"2015-01-11T07:08:00.159-08:00","display_name":"Jia Hao","url":"https://independent.academia.edu/JiaHao2"},"attachments":[],"research_interests":[{"id":523,"name":"Chemistry","url":"https://www.academia.edu/Documents/in/Chemistry"},{"id":524,"name":"Analytical Chemistry","url":"https://www.academia.edu/Documents/in/Analytical_Chemistry"},{"id":4656,"name":"Chromatography","url":"https://www.academia.edu/Documents/in/Chromatography"},{"id":7698,"name":"Fluorescence","url":"https://www.academia.edu/Documents/in/Fluorescence"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":163275,"name":"Tandem Mass Spectrometry","url":"https://www.academia.edu/Documents/in/Tandem_Mass_Spectrometry"},{"id":178360,"name":"Urine","url":"https://www.academia.edu/Documents/in/Urine"},{"id":204350,"name":"Anti-inflammatory agents","url":"https://www.academia.edu/Documents/in/Anti-inflammatory_agents"},{"id":205461,"name":"Bioavailability","url":"https://www.academia.edu/Documents/in/Bioavailability"},{"id":225787,"name":"High Performance Liquid Chromatography","url":"https://www.academia.edu/Documents/in/High_Performance_Liquid_Chromatography"},{"id":246560,"name":"High Pressure Liquid Chromatography","url":"https://www.academia.edu/Documents/in/High_Pressure_Liquid_Chromatography"},{"id":375054,"name":"Rats","url":"https://www.academia.edu/Documents/in/Rats"},{"id":727024,"name":"ADME","url":"https://www.academia.edu/Documents/in/ADME"},{"id":1136192,"name":"Biological Availability","url":"https://www.academia.edu/Documents/in/Biological_Availability"},{"id":1223894,"name":"Metabolite","url":"https://www.academia.edu/Documents/in/Metabolite"},{"id":3549129,"name":"excretion","url":"https://www.academia.edu/Documents/in/excretion"},{"id":3789884,"name":"Pharmacology and pharmaceutical sciences","url":"https://www.academia.edu/Documents/in/Pharmacology_and_pharmaceutical_sciences"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="105758745"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/105758745/An_evolutionary_computation_based_method_for_creative_design_inspiration_generation"><img alt="Research paper thumbnail of An evolutionary computation based method for creative design inspiration generation" class="work-thumbnail" src="https://attachments.academia-assets.com/105137876/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/105758745/An_evolutionary_computation_based_method_for_creative_design_inspiration_generation">An evolutionary computation based method for creative design inspiration generation</a></div><div class="wp-workCard_item"><span>Journal of Intelligent Manufacturing</span><span>, 2017</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="6f246d5c980043b456d17e831a600bb5" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":105137876,"asset_id":105758745,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/105137876/download_file?st=MTczMjczOTk3NCw4LjIyMi4yMDguMTQ2&st=MTczMjczOTk3Myw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="105758745"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="105758745"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 105758745; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=105758745]").text(description); $(".js-view-count[data-work-id=105758745]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 105758745; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='105758745']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 105758745, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "6f246d5c980043b456d17e831a600bb5" } } $('.js-work-strip[data-work-id=105758745]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":105758745,"title":"An evolutionary computation based method for creative design inspiration generation","translated_title":"","metadata":{"publisher":"Springer Science and Business Media LLC","grobid_abstract":"Product design is an important part of the manufacturing system from a macro point of view. In the design process, creative design is one of the important factors to survive the fierce competition. During creative design process, designers are the most critical component. However, design fixation often negatively influences the design outcomes. Many researches from cognitive science and design science reveal that the presentation of outer information can alleviate design fixation effectively. Among different kinds of outer information, language terms are proved to be effective. This work presents a method of automatically generating language terms as design inspirations based on 500,000 granted patents. This method adopts evolutionary computation as the fundamental algorithm to retrieve language terms from a vocabulary base. To implement the algorithm, the vocabulary is first encoded by high dimensional vectors through word embedding, which is a three layers neural network. Further, two metrics for measuring the inspiration potential of language terms are defined in a computable manner. This work also conducts experiments to validate the method, and the experimental results show that (1) the algorithm is efficient and has the potential to be extended to larger vocabulary; (2) B Jia Hao","publication_date":{"day":null,"month":null,"year":2017,"errors":{}},"publication_name":"Journal of Intelligent Manufacturing","grobid_abstract_attachment_id":105137876},"translated_abstract":null,"internal_url":"https://www.academia.edu/105758745/An_evolutionary_computation_based_method_for_creative_design_inspiration_generation","translated_internal_url":"","created_at":"2023-08-19T17:55:06.893-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":24656298,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":105137876,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/105137876/thumbnails/1.jpg","file_name":"s10845-017-1347-x20230820-1-cs4f30.pdf","download_url":"https://www.academia.edu/attachments/105137876/download_file?st=MTczMjczOTk3NCw4LjIyMi4yMDguMTQ2&st=MTczMjczOTk3Myw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"An_evolutionary_computation_based_method.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/105137876/s10845-017-1347-x20230820-1-cs4f30-libre.pdf?1692497783=\u0026response-content-disposition=attachment%3B+filename%3DAn_evolutionary_computation_based_method.pdf\u0026Expires=1732743573\u0026Signature=c-kyut5bNyNcqtpPETeVcFMiDsixswsRvHh3zAKo7ga5Vjtk1xM0jCwDpL7toGLdaWFD~tqGOFC~5-lkiO1GSSzUsaZLRP5blOKoAMxfpNVA-83JlErkOUot-HA6vX9aEPphfRKg-BdGFqi~~BtkeCySgn~rY81OHPfuHOUHhjI0cRro3I31eSYGhhCA09N-YMWbpTyWe1ENuWBpA1x-HKgNK2XX2kZNqBUQG9dIUOODx7KMHkpRvKP-r4~ESynLBARel5j2NEaFV43Yfi~9QccQLYW6w1fEDspwBx-69yJotpH897ZSSoF8rM~cG50kEqq4HpvXPXxS-NV2FggOWA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"An_evolutionary_computation_based_method_for_creative_design_inspiration_generation","translated_slug":"","page_count":19,"language":"en","content_type":"Work","owner":{"id":24656298,"first_name":"Jia","middle_initials":null,"last_name":"Hao","page_name":"JiaHao2","domain_name":"independent","created_at":"2015-01-11T07:08:00.159-08:00","display_name":"Jia Hao","url":"https://independent.academia.edu/JiaHao2"},"attachments":[{"id":105137876,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/105137876/thumbnails/1.jpg","file_name":"s10845-017-1347-x20230820-1-cs4f30.pdf","download_url":"https://www.academia.edu/attachments/105137876/download_file?st=MTczMjczOTk3NCw4LjIyMi4yMDguMTQ2&st=MTczMjczOTk3Myw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"An_evolutionary_computation_based_method.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/105137876/s10845-017-1347-x20230820-1-cs4f30-libre.pdf?1692497783=\u0026response-content-disposition=attachment%3B+filename%3DAn_evolutionary_computation_based_method.pdf\u0026Expires=1732743573\u0026Signature=c-kyut5bNyNcqtpPETeVcFMiDsixswsRvHh3zAKo7ga5Vjtk1xM0jCwDpL7toGLdaWFD~tqGOFC~5-lkiO1GSSzUsaZLRP5blOKoAMxfpNVA-83JlErkOUot-HA6vX9aEPphfRKg-BdGFqi~~BtkeCySgn~rY81OHPfuHOUHhjI0cRro3I31eSYGhhCA09N-YMWbpTyWe1ENuWBpA1x-HKgNK2XX2kZNqBUQG9dIUOODx7KMHkpRvKP-r4~ESynLBARel5j2NEaFV43Yfi~9QccQLYW6w1fEDspwBx-69yJotpH897ZSSoF8rM~cG50kEqq4HpvXPXxS-NV2FggOWA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":422,"name":"Computer Science","url":"https://www.academia.edu/Documents/in/Computer_Science"},{"id":46604,"name":"Intelligent Manufacturing","url":"https://www.academia.edu/Documents/in/Intelligent_Manufacturing"},{"id":59487,"name":"Computation","url":"https://www.academia.edu/Documents/in/Computation"},{"id":96825,"name":"Manufacturing Engineering","url":"https://www.academia.edu/Documents/in/Manufacturing_Engineering"}],"urls":[{"id":33510684,"url":"http://link.springer.com/content/pdf/10.1007/s10845-017-1347-x.pdf"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="105758744"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/105758744/The_Method_of_Failure_Data_Processing_Analysis_of_Filling_System_in_Launching_Site_Based_on_Bayesian_Method"><img alt="Research paper thumbnail of The Method of Failure Data Processing Analysis of Filling System in Launching Site Based on Bayesian Method" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/105758744/The_Method_of_Failure_Data_Processing_Analysis_of_Filling_System_in_Launching_Site_Based_on_Bayesian_Method">The Method of Failure Data Processing Analysis of Filling System in Launching Site Based on Bayesian Method</a></div><div class="wp-workCard_item"><span>Applied Mechanics and Materials</span><span>, 2014</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The high reliability and the short times carried of quantitative risk assessment of Filling syste...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The high reliability and the short times carried of quantitative risk assessment of Filling system in launching site, the failure data is small sample data. In this paper, we will focus on these small sample data and take processing analysis. A method based on Bayesian method of failure data processing analysis of Filling system has been proposed, which firstly analyzes the characteristic of failure data of Filling system. Secondly, we classify the failure data into running failure data and demanding data according to the data types, and further analyze various uncertainty distributions under this two kinds of data type. What’s more, we use Bayesian method to solve the problems of various failure data. Lastly, we combine the real circumstance of Filling system and take the Filling system as example, and choose the filling pump, shut-off valve and pneumatic ball valve these three different failure types to use Bayesian method to analyze, and obtain various prior distributions and pos...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="105758744"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="105758744"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 105758744; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=105758744]").text(description); $(".js-view-count[data-work-id=105758744]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 105758744; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='105758744']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 105758744, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=105758744]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":105758744,"title":"The Method of Failure Data Processing Analysis of Filling System in Launching Site Based on Bayesian Method","translated_title":"","metadata":{"abstract":"The high reliability and the short times carried of quantitative risk assessment of Filling system in launching site, the failure data is small sample data. In this paper, we will focus on these small sample data and take processing analysis. A method based on Bayesian method of failure data processing analysis of Filling system has been proposed, which firstly analyzes the characteristic of failure data of Filling system. Secondly, we classify the failure data into running failure data and demanding data according to the data types, and further analyze various uncertainty distributions under this two kinds of data type. What’s more, we use Bayesian method to solve the problems of various failure data. Lastly, we combine the real circumstance of Filling system and take the Filling system as example, and choose the filling pump, shut-off valve and pneumatic ball valve these three different failure types to use Bayesian method to analyze, and obtain various prior distributions and pos...","publisher":"Trans Tech Publications","publication_date":{"day":null,"month":null,"year":2014,"errors":{}},"publication_name":"Applied Mechanics and Materials"},"translated_abstract":"The high reliability and the short times carried of quantitative risk assessment of Filling system in launching site, the failure data is small sample data. In this paper, we will focus on these small sample data and take processing analysis. A method based on Bayesian method of failure data processing analysis of Filling system has been proposed, which firstly analyzes the characteristic of failure data of Filling system. Secondly, we classify the failure data into running failure data and demanding data according to the data types, and further analyze various uncertainty distributions under this two kinds of data type. What’s more, we use Bayesian method to solve the problems of various failure data. Lastly, we combine the real circumstance of Filling system and take the Filling system as example, and choose the filling pump, shut-off valve and pneumatic ball valve these three different failure types to use Bayesian method to analyze, and obtain various prior distributions and pos...","internal_url":"https://www.academia.edu/105758744/The_Method_of_Failure_Data_Processing_Analysis_of_Filling_System_in_Launching_Site_Based_on_Bayesian_Method","translated_internal_url":"","created_at":"2023-08-19T17:55:06.228-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":24656298,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"The_Method_of_Failure_Data_Processing_Analysis_of_Filling_System_in_Launching_Site_Based_on_Bayesian_Method","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":24656298,"first_name":"Jia","middle_initials":null,"last_name":"Hao","page_name":"JiaHao2","domain_name":"independent","created_at":"2015-01-11T07:08:00.159-08:00","display_name":"Jia Hao","url":"https://independent.academia.edu/JiaHao2"},"attachments":[],"research_interests":[{"id":48,"name":"Engineering","url":"https://www.academia.edu/Documents/in/Engineering"},{"id":2009,"name":"Data Mining","url":"https://www.academia.edu/Documents/in/Data_Mining"},{"id":581652,"name":"Data Processing","url":"https://www.academia.edu/Documents/in/Data_Processing"},{"id":1032783,"name":"Bayesian Probability","url":"https://www.academia.edu/Documents/in/Bayesian_Probability"}],"urls":[{"id":33510683,"url":"http://www.scientific.net/AMM.644-650.2537.pdf"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="105758743"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/105758743/Study_on_High_Performance_Simulation_Computer_for_Large_Scale_System_of_Systems_Simulation"><img alt="Research paper thumbnail of Study on High-Performance Simulation Computer for Large-Scale System of Systems Simulation" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/105758743/Study_on_High_Performance_Simulation_Computer_for_Large_Scale_System_of_Systems_Simulation">Study on High-Performance Simulation Computer for Large-Scale System of Systems Simulation</a></div><div class="wp-workCard_item"><span>Applied Mechanics and Materials</span><span>, 2014</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The high-performance parallel computing (HPPC) has a better overall performance and higher produc...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The high-performance parallel computing (HPPC) has a better overall performance and higher productivity, for a generical large-scale army equipment system of systems (AESoS) simulation, and the runtime efficiency can be multiplied several tenfold to several hundredfold. The requirement analysis of simulation framework of AESoS based on HPPC was proposed. After the simulation framework of AESoS based on HPPC and its key techniques were discussed, the simulation framework of AESoS Based HPPC was designed. it is of great significance to offer certain references for the engineering application in the simulation fields of AESoS based on HPPC.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="105758743"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="105758743"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 105758743; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=105758743]").text(description); $(".js-view-count[data-work-id=105758743]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 105758743; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='105758743']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 105758743, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=105758743]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":105758743,"title":"Study on High-Performance Simulation Computer for Large-Scale System of Systems Simulation","translated_title":"","metadata":{"abstract":"The high-performance parallel computing (HPPC) has a better overall performance and higher productivity, for a generical large-scale army equipment system of systems (AESoS) simulation, and the runtime efficiency can be multiplied several tenfold to several hundredfold. The requirement analysis of simulation framework of AESoS based on HPPC was proposed. After the simulation framework of AESoS based on HPPC and its key techniques were discussed, the simulation framework of AESoS Based HPPC was designed. it is of great significance to offer certain references for the engineering application in the simulation fields of AESoS based on HPPC.","publisher":"Trans Tech Publications","publication_date":{"day":null,"month":null,"year":2014,"errors":{}},"publication_name":"Applied Mechanics and Materials"},"translated_abstract":"The high-performance parallel computing (HPPC) has a better overall performance and higher productivity, for a generical large-scale army equipment system of systems (AESoS) simulation, and the runtime efficiency can be multiplied several tenfold to several hundredfold. The requirement analysis of simulation framework of AESoS based on HPPC was proposed. After the simulation framework of AESoS based on HPPC and its key techniques were discussed, the simulation framework of AESoS Based HPPC was designed. it is of great significance to offer certain references for the engineering application in the simulation fields of AESoS based on HPPC.","internal_url":"https://www.academia.edu/105758743/Study_on_High_Performance_Simulation_Computer_for_Large_Scale_System_of_Systems_Simulation","translated_internal_url":"","created_at":"2023-08-19T17:55:06.010-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":24656298,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Study_on_High_Performance_Simulation_Computer_for_Large_Scale_System_of_Systems_Simulation","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":24656298,"first_name":"Jia","middle_initials":null,"last_name":"Hao","page_name":"JiaHao2","domain_name":"independent","created_at":"2015-01-11T07:08:00.159-08:00","display_name":"Jia Hao","url":"https://independent.academia.edu/JiaHao2"},"attachments":[],"research_interests":[{"id":48,"name":"Engineering","url":"https://www.academia.edu/Documents/in/Engineering"},{"id":422,"name":"Computer Science","url":"https://www.academia.edu/Documents/in/Computer_Science"},{"id":99926,"name":"System of Systems","url":"https://www.academia.edu/Documents/in/System_of_Systems"}],"urls":[{"id":33510682,"url":"http://www.scientific.net/AMM.548-549.1311.pdf"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="105758742"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/105758742/Modeling_and_optimizing_inhibitory_activities_of_Nelumbinis_folium_extract_on_xanthine_oxidase_using_response_surface_methodology"><img alt="Research paper thumbnail of Modeling and optimizing inhibitory activities of Nelumbinis folium extract on xanthine oxidase using response surface methodology" class="work-thumbnail" src="https://attachments.academia-assets.com/105137862/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/105758742/Modeling_and_optimizing_inhibitory_activities_of_Nelumbinis_folium_extract_on_xanthine_oxidase_using_response_surface_methodology">Modeling and optimizing inhibitory activities of Nelumbinis folium extract on xanthine oxidase using response surface methodology</a></div><div class="wp-workCard_item"><span>Journal of pharmaceutical and biomedical analysis</span><span>, 2017</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Xanthine oxidase (XOD), which could oxidize hypoxanthine to xanthine and then to uric acid, is a ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Xanthine oxidase (XOD), which could oxidize hypoxanthine to xanthine and then to uric acid, is a key enzyme in the pathogenesis of hyperuricemia and also a well-known target for the drug development to treat gout. In our study, the total alkaloids of Nelumbinis folium markedly inhibited XOD activity, with IC50 value being 3.313μg/mL. UHPLC-Q-TOF-MS and 3D docking analysis indicated that roemerine was a potential active ingredient. A response surface methodology combined with central composite design experiment was further developed and validated for the optimization of the reaction conditions between the total alkaloids of Nelumbinis folium and XOD, which could be considered as a meaningful research for the development of XOD inhibitor rapidly and sensitively.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="40342a22e5669ec72cf42e60c8712255" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":105137862,"asset_id":105758742,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/105137862/download_file?st=MTczMjczOTk3NCw4LjIyMi4yMDguMTQ2&st=MTczMjczOTk3Myw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="105758742"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="105758742"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 105758742; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=105758742]").text(description); $(".js-view-count[data-work-id=105758742]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 105758742; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='105758742']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 105758742, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "40342a22e5669ec72cf42e60c8712255" } } $('.js-work-strip[data-work-id=105758742]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":105758742,"title":"Modeling and optimizing inhibitory activities of Nelumbinis folium extract on xanthine oxidase using response surface methodology","translated_title":"","metadata":{"abstract":"Xanthine oxidase (XOD), which could oxidize hypoxanthine to xanthine and then to uric acid, is a key enzyme in the pathogenesis of hyperuricemia and also a well-known target for the drug development to treat gout. 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UHPLC-Q-TOF-MS and 3D docking analysis indicated that roemerine was a potential active ingredient. A response surface methodology combined with central composite design experiment was further developed and validated for the optimization of the reaction conditions between the total alkaloids of Nelumbinis folium and XOD, which could be considered as a meaningful research for the development of XOD inhibitor rapidly and sensitively.","internal_url":"https://www.academia.edu/105758742/Modeling_and_optimizing_inhibitory_activities_of_Nelumbinis_folium_extract_on_xanthine_oxidase_using_response_surface_methodology","translated_internal_url":"","created_at":"2023-08-19T17:55:05.814-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":24656298,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":105137862,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/105137862/thumbnails/1.jpg","file_name":"j.jpba.2017.02.04820230820-1-fkdkrm.pdf","download_url":"https://www.academia.edu/attachments/105137862/download_file?st=MTczMjczOTk3NCw4LjIyMi4yMDguMTQ2&st=MTczMjczOTk3Myw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Modeling_and_optimizing_inhibitory_activ.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/105137862/j.jpba.2017.02.04820230820-1-fkdkrm-libre.pdf?1692497783=\u0026response-content-disposition=attachment%3B+filename%3DModeling_and_optimizing_inhibitory_activ.pdf\u0026Expires=1732743573\u0026Signature=LFy1tceDndWtxGDow0t4NEyTK6POxdxP3VlGRbOC8oSFi3LoQD9xSf3m9wrLRusFfADie3qB0m8iBUeFhb6Wq7vtyQYaIf2TMidLEp8fYPnABlGL304DpMjtqTzy6-rjZ7r3yaYpxpw7TVpVw3v8Hi5~smaQLPZmfdqXjakMAG~LxMz2nrvp0OZ45AUe9VvCUFdaRa~HC646vPLNoW7n~rD7JyIrKYKF2CoGGzp0116tI8Gnqn8BucxMCNPhadCDBEUawKAmqEoOWn8r4ZbdmCcyFmCS9TLgbExgjIFRPyVgoPeL1rLKTHcuOMALl7zHNssG0IlpeXDmJ-oytAf7BA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Modeling_and_optimizing_inhibitory_activities_of_Nelumbinis_folium_extract_on_xanthine_oxidase_using_response_surface_methodology","translated_slug":"","page_count":20,"language":"en","content_type":"Work","owner":{"id":24656298,"first_name":"Jia","middle_initials":null,"last_name":"Hao","page_name":"JiaHao2","domain_name":"independent","created_at":"2015-01-11T07:08:00.159-08:00","display_name":"Jia Hao","url":"https://independent.academia.edu/JiaHao2"},"attachments":[{"id":105137862,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/105137862/thumbnails/1.jpg","file_name":"j.jpba.2017.02.04820230820-1-fkdkrm.pdf","download_url":"https://www.academia.edu/attachments/105137862/download_file?st=MTczMjczOTk3NCw4LjIyMi4yMDguMTQ2&st=MTczMjczOTk3Myw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Modeling_and_optimizing_inhibitory_activ.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/105137862/j.jpba.2017.02.04820230820-1-fkdkrm-libre.pdf?1692497783=\u0026response-content-disposition=attachment%3B+filename%3DModeling_and_optimizing_inhibitory_activ.pdf\u0026Expires=1732743573\u0026Signature=LFy1tceDndWtxGDow0t4NEyTK6POxdxP3VlGRbOC8oSFi3LoQD9xSf3m9wrLRusFfADie3qB0m8iBUeFhb6Wq7vtyQYaIf2TMidLEp8fYPnABlGL304DpMjtqTzy6-rjZ7r3yaYpxpw7TVpVw3v8Hi5~smaQLPZmfdqXjakMAG~LxMz2nrvp0OZ45AUe9VvCUFdaRa~HC646vPLNoW7n~rD7JyIrKYKF2CoGGzp0116tI8Gnqn8BucxMCNPhadCDBEUawKAmqEoOWn8r4ZbdmCcyFmCS9TLgbExgjIFRPyVgoPeL1rLKTHcuOMALl7zHNssG0IlpeXDmJ-oytAf7BA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":140,"name":"Pharmacology","url":"https://www.academia.edu/Documents/in/Pharmacology"},{"id":523,"name":"Chemistry","url":"https://www.academia.edu/Documents/in/Chemistry"},{"id":524,"name":"Analytical Chemistry","url":"https://www.academia.edu/Documents/in/Analytical_Chemistry"},{"id":9508,"name":"Response Surface Methodology","url":"https://www.academia.edu/Documents/in/Response_Surface_Methodology"},{"id":12981,"name":"Enzyme Inhibitors","url":"https://www.academia.edu/Documents/in/Enzyme_Inhibitors"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":62970,"name":"Nelumbo","url":"https://www.academia.edu/Documents/in/Nelumbo"},{"id":102739,"name":"Ic","url":"https://www.academia.edu/Documents/in/Ic"},{"id":227305,"name":"Hyperuricemia","url":"https://www.academia.edu/Documents/in/Hyperuricemia"},{"id":309088,"name":"Uric Acid","url":"https://www.academia.edu/Documents/in/Uric_Acid"},{"id":354056,"name":"Plant extracts","url":"https://www.academia.edu/Documents/in/Plant_extracts"},{"id":1546570,"name":"Xanthine Oxidase","url":"https://www.academia.edu/Documents/in/Xanthine_Oxidase"},{"id":1905343,"name":"Plant Leaves","url":"https://www.academia.edu/Documents/in/Plant_Leaves"},{"id":3789884,"name":"Pharmacology and pharmaceutical sciences","url":"https://www.academia.edu/Documents/in/Pharmacology_and_pharmaceutical_sciences"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="105758741"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/105758741/Ligature_induced_peri_implantitis_tissue_destruction_and_inflammatory_progression_in_a_murine_model"><img alt="Research paper thumbnail of Ligature induced peri-implantitis: tissue destruction and inflammatory progression in a murine model" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/105758741/Ligature_induced_peri_implantitis_tissue_destruction_and_inflammatory_progression_in_a_murine_model">Ligature induced peri-implantitis: tissue destruction and inflammatory progression in a murine model</a></div><div class="wp-workCard_item"><span>Clinical Oral Implants Research</span><span>, 2016</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The aim of this study was to investigate tissue destruction and inflammatory progression of ligat...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The aim of this study was to investigate tissue destruction and inflammatory progression of ligature-induced peri-implantitis in mice and to establish an alternative murine model of peri-implantitis. Sixty male C57BL/6NCrSlc mice (4-week-old) were used and the maxillary right first molars were extracted. Eight weeks after extraction, custom-made pure titanium machined screw type implants (0.8 × 1.5 mm) were placed, one implant per animal. Four weeks later, 5-0 silk ligatures were applied around implant necks to induce peri-implantitis. Animals were sacrificed at 0 (before ligature), 7, 14, 21 and 28 days after ligature. Half of the samples were analyzed radiologically and histologically to measure bone level change, osteoclast number, density, and distribution. The rest of the samples was used to determine the relative mRNA expression levels of IL-1 and TNF-α with RT-PCR analysis. Bone levels at all sites (buccal, palatal, mesial, distal) decreased 40-50% significantly 28 days after ligature (P &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.01). Osteoclast number at all post-ligature time points increased significantly (P &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.05). However, their density at day 28 decreased significantly compared to that of day 21 (P &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.05). Accordingly, IL-1 and TNF-α mRNA expression increased significantly at the early time points but decreased significantly at day 28 after ligature (P &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.05). Inflammatory response followed by significant peri-implant bone resorption suggested 28 days ligation is sufficient to successfully induce peri-implantitis in the current mice model. This model might open a new avenue to study the pathogenesis and mechanism of peri-implantitis.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="105758741"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="105758741"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 105758741; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=105758741]").text(description); $(".js-view-count[data-work-id=105758741]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 105758741; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='105758741']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 105758741, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=105758741]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":105758741,"title":"Ligature induced peri-implantitis: tissue destruction and inflammatory progression in a murine model","translated_title":"","metadata":{"abstract":"The aim of this study was to investigate tissue destruction and inflammatory progression of ligature-induced peri-implantitis in mice and to establish an alternative murine model of peri-implantitis. Sixty male C57BL/6NCrSlc mice (4-week-old) were used and the maxillary right first molars were extracted. Eight weeks after extraction, custom-made pure titanium machined screw type implants (0.8 × 1.5 mm) were placed, one implant per animal. Four weeks later, 5-0 silk ligatures were applied around implant necks to induce peri-implantitis. Animals were sacrificed at 0 (before ligature), 7, 14, 21 and 28 days after ligature. Half of the samples were analyzed radiologically and histologically to measure bone level change, osteoclast number, density, and distribution. The rest of the samples was used to determine the relative mRNA expression levels of IL-1 and TNF-α with RT-PCR analysis. Bone levels at all sites (buccal, palatal, mesial, distal) decreased 40-50% significantly 28 days after ligature (P \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.01). Osteoclast number at all post-ligature time points increased significantly (P \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.05). However, their density at day 28 decreased significantly compared to that of day 21 (P \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.05). Accordingly, IL-1 and TNF-α mRNA expression increased significantly at the early time points but decreased significantly at day 28 after ligature (P \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.05). Inflammatory response followed by significant peri-implant bone resorption suggested 28 days ligation is sufficient to successfully induce peri-implantitis in the current mice model. This model might open a new avenue to study the pathogenesis and mechanism of peri-implantitis.","publisher":"Wiley","publication_date":{"day":null,"month":null,"year":2016,"errors":{}},"publication_name":"Clinical Oral Implants Research"},"translated_abstract":"The aim of this study was to investigate tissue destruction and inflammatory progression of ligature-induced peri-implantitis in mice and to establish an alternative murine model of peri-implantitis. Sixty male C57BL/6NCrSlc mice (4-week-old) were used and the maxillary right first molars were extracted. Eight weeks after extraction, custom-made pure titanium machined screw type implants (0.8 × 1.5 mm) were placed, one implant per animal. Four weeks later, 5-0 silk ligatures were applied around implant necks to induce peri-implantitis. Animals were sacrificed at 0 (before ligature), 7, 14, 21 and 28 days after ligature. Half of the samples were analyzed radiologically and histologically to measure bone level change, osteoclast number, density, and distribution. The rest of the samples was used to determine the relative mRNA expression levels of IL-1 and TNF-α with RT-PCR analysis. Bone levels at all sites (buccal, palatal, mesial, distal) decreased 40-50% significantly 28 days after ligature (P \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.01). Osteoclast number at all post-ligature time points increased significantly (P \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.05). However, their density at day 28 decreased significantly compared to that of day 21 (P \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.05). Accordingly, IL-1 and TNF-α mRNA expression increased significantly at the early time points but decreased significantly at day 28 after ligature (P \u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt; 0.05). Inflammatory response followed by significant peri-implant bone resorption suggested 28 days ligation is sufficient to successfully induce peri-implantitis in the current mice model. This model might open a new avenue to study the pathogenesis and mechanism of peri-implantitis.","internal_url":"https://www.academia.edu/105758741/Ligature_induced_peri_implantitis_tissue_destruction_and_inflammatory_progression_in_a_murine_model","translated_internal_url":"","created_at":"2023-08-19T17:55:05.593-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":24656298,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Ligature_induced_peri_implantitis_tissue_destruction_and_inflammatory_progression_in_a_murine_model","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":24656298,"first_name":"Jia","middle_initials":null,"last_name":"Hao","page_name":"JiaHao2","domain_name":"independent","created_at":"2015-01-11T07:08:00.159-08:00","display_name":"Jia Hao","url":"https://independent.academia.edu/JiaHao2"},"attachments":[],"research_interests":[{"id":596,"name":"Dentistry","url":"https://www.academia.edu/Documents/in/Dentistry"},{"id":1131,"name":"Biomedical Engineering","url":"https://www.academia.edu/Documents/in/Biomedical_Engineering"},{"id":6970,"name":"Biomarkers","url":"https://www.academia.edu/Documents/in/Biomarkers"},{"id":9334,"name":"Inflammation","url":"https://www.academia.edu/Documents/in/Inflammation"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":84760,"name":"Mice","url":"https://www.academia.edu/Documents/in/Mice"},{"id":185112,"name":"Maxilla","url":"https://www.academia.edu/Documents/in/Maxilla"},{"id":407481,"name":"Implant","url":"https://www.academia.edu/Documents/in/Implant"},{"id":474029,"name":"Tumor necrosis factor-alpha","url":"https://www.academia.edu/Documents/in/Tumor_necrosis_factor-alpha"},{"id":584615,"name":"Disease Progression","url":"https://www.academia.edu/Documents/in/Disease_Progression"},{"id":1027671,"name":"Resorption","url":"https://www.academia.edu/Documents/in/Resorption"},{"id":1238472,"name":"Peri-implantitis","url":"https://www.academia.edu/Documents/in/Peri-implantitis"},{"id":1399820,"name":"Bone Resorption","url":"https://www.academia.edu/Documents/in/Bone_Resorption"},{"id":1924712,"name":"Interleukin","url":"https://www.academia.edu/Documents/in/Interleukin"},{"id":2940273,"name":"real time polymerase chain reaction","url":"https://www.academia.edu/Documents/in/real_time_polymerase_chain_reaction"},{"id":3197061,"name":"Molar","url":"https://www.academia.edu/Documents/in/Molar"},{"id":3589281,"name":"Ligation","url":"https://www.academia.edu/Documents/in/Ligation"}],"urls":[{"id":33510681,"url":"http://onlinelibrary.wiley.com/wol1/doi/10.1111/clr.12770/fullpdf"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="105758740"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/105758740/Towards_dose_reduction_for_dual_energy_CT_A_non_local_image_improvement_method_and_its_application"><img alt="Research paper thumbnail of Towards dose reduction for dual-energy CT: A non-local image improvement method and its application" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/105758740/Towards_dose_reduction_for_dual_energy_CT_A_non_local_image_improvement_method_and_its_application">Towards dose reduction for dual-energy CT: A non-local image improvement method and its application</a></div><div class="wp-workCard_item"><span>Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment</span><span>, 2015</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">ABSTRACT Dual-energy CT (DECT) has better material discrimination capability than single-energy C...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">ABSTRACT Dual-energy CT (DECT) has better material discrimination capability than single-energy CT. In this paper, we propose a low-dose DECT scanning strategy with double scans under different energy spectra. In the strategy a low-energy scan is performed with a complete number of views, and the high-energy scan is in much sparser views to reduce radiation dose. In such conditions, the high-energy reconstruction image suffers from severe streak artifacts due to under-sampling. To address this problem a novel non-local image restoration method is proposed. Because the low and high energy scans are performed on the same object, the reconstructed images should have identical object structures. Therefore the low-energy reconstruction that comes from the complete scan may serve as a reference image to help improving the image quality of the high-energy reconstruction. The method is implemented with the following steps. First, the structure information is obtained by a non-local pixel similarity measurement on the low-energy CT image, and second after a registration between the high and low reconstructions the high-energy image is restored by normalized weighted average using the calculated similarity relationship. Compared with previous methods, the new method achieves better image quality in both structure preservation and artifact reduction. Besides, the computation is much cheaper than iterative reconstruction methods, which makes the method of practical value. Numerical and pre-clinical experiments have been performed to illustrate the effectiveness of the proposed method. With the novel DECT scanning configuration and non-local image restoration method, the total dose is significantly reduced while maintaining a high reconstruction quality.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="105758740"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="105758740"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 105758740; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=105758740]").text(description); $(".js-view-count[data-work-id=105758740]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 105758740; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='105758740']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 105758740, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=105758740]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":105758740,"title":"Towards dose reduction for dual-energy CT: A non-local image improvement method and its application","translated_title":"","metadata":{"abstract":"ABSTRACT Dual-energy CT (DECT) has better material discrimination capability than single-energy CT. In this paper, we propose a low-dose DECT scanning strategy with double scans under different energy spectra. In the strategy a low-energy scan is performed with a complete number of views, and the high-energy scan is in much sparser views to reduce radiation dose. In such conditions, the high-energy reconstruction image suffers from severe streak artifacts due to under-sampling. To address this problem a novel non-local image restoration method is proposed. Because the low and high energy scans are performed on the same object, the reconstructed images should have identical object structures. Therefore the low-energy reconstruction that comes from the complete scan may serve as a reference image to help improving the image quality of the high-energy reconstruction. The method is implemented with the following steps. First, the structure information is obtained by a non-local pixel similarity measurement on the low-energy CT image, and second after a registration between the high and low reconstructions the high-energy image is restored by normalized weighted average using the calculated similarity relationship. Compared with previous methods, the new method achieves better image quality in both structure preservation and artifact reduction. Besides, the computation is much cheaper than iterative reconstruction methods, which makes the method of practical value. Numerical and pre-clinical experiments have been performed to illustrate the effectiveness of the proposed method. With the novel DECT scanning configuration and non-local image restoration method, the total dose is significantly reduced while maintaining a high reconstruction quality.","publisher":"Elsevier BV","publication_date":{"day":null,"month":null,"year":2015,"errors":{}},"publication_name":"Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment"},"translated_abstract":"ABSTRACT Dual-energy CT (DECT) has better material discrimination capability than single-energy CT. In this paper, we propose a low-dose DECT scanning strategy with double scans under different energy spectra. In the strategy a low-energy scan is performed with a complete number of views, and the high-energy scan is in much sparser views to reduce radiation dose. In such conditions, the high-energy reconstruction image suffers from severe streak artifacts due to under-sampling. To address this problem a novel non-local image restoration method is proposed. Because the low and high energy scans are performed on the same object, the reconstructed images should have identical object structures. Therefore the low-energy reconstruction that comes from the complete scan may serve as a reference image to help improving the image quality of the high-energy reconstruction. The method is implemented with the following steps. First, the structure information is obtained by a non-local pixel similarity measurement on the low-energy CT image, and second after a registration between the high and low reconstructions the high-energy image is restored by normalized weighted average using the calculated similarity relationship. Compared with previous methods, the new method achieves better image quality in both structure preservation and artifact reduction. Besides, the computation is much cheaper than iterative reconstruction methods, which makes the method of practical value. Numerical and pre-clinical experiments have been performed to illustrate the effectiveness of the proposed method. With the novel DECT scanning configuration and non-local image restoration method, the total dose is significantly reduced while maintaining a high reconstruction quality.","internal_url":"https://www.academia.edu/105758740/Towards_dose_reduction_for_dual_energy_CT_A_non_local_image_improvement_method_and_its_application","translated_internal_url":"","created_at":"2023-08-19T17:55:05.424-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":24656298,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Towards_dose_reduction_for_dual_energy_CT_A_non_local_image_improvement_method_and_its_application","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":24656298,"first_name":"Jia","middle_initials":null,"last_name":"Hao","page_name":"JiaHao2","domain_name":"independent","created_at":"2015-01-11T07:08:00.159-08:00","display_name":"Jia Hao","url":"https://independent.academia.edu/JiaHao2"},"attachments":[],"research_interests":[{"id":422,"name":"Computer Science","url":"https://www.academia.edu/Documents/in/Computer_Science"},{"id":465,"name":"Artificial Intelligence","url":"https://www.academia.edu/Documents/in/Artificial_Intelligence"},{"id":498,"name":"Physics","url":"https://www.academia.edu/Documents/in/Physics"},{"id":854,"name":"Computer Vision","url":"https://www.academia.edu/Documents/in/Computer_Vision"},{"id":30415,"name":"Image Quality","url":"https://www.academia.edu/Documents/in/Image_Quality"},{"id":1707689,"name":"Pixel","url":"https://www.academia.edu/Documents/in/Pixel"},{"id":2466378,"name":"Iterative Reconstruction","url":"https://www.academia.edu/Documents/in/Iterative_Reconstruction"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="105758739"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/105758739/Does_Removing_the_Short_sale_Constraint_Improve_Liquidity_Evidence_from_Hong_Kong"><img alt="Research paper thumbnail of Does Removing the Short-sale Constraint Improve Liquidity? Evidence from Hong Kong" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/105758739/Does_Removing_the_Short_sale_Constraint_Improve_Liquidity_Evidence_from_Hong_Kong">Does Removing the Short-sale Constraint Improve Liquidity? Evidence from Hong Kong</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">The short-sale regulations in Hong Kong provide a unique setting to examine the effects of short-...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">The short-sale regulations in Hong Kong provide a unique setting to examine the effects of short- sale constraints on stock market liquidity. Short selling of stocks was prohibited in Hong Kong till 1994. The restrictions were relaxed over a period of eight years in our sample period. We find that removing the short-sale constraints increased the liquidity of lower priced stocks but not higher priced ones. Low priced and high priced stocks had comparable market capitalizations in Hong Kong. However, lower priced stocks had less publicly available information - they had larger adverse selection components in their bid-ask spreads and less sell-side analyst coverage. We also find that the &quot;uptick rule&quot; significantly decreases the market quality. Finally we do not find any evidence that relaxing the short-sale constraints increases total volatilities, upside volatilities, or downside volatilities.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="105758739"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="105758739"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 105758739; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=105758739]").text(description); $(".js-view-count[data-work-id=105758739]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 105758739; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='105758739']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 105758739, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=105758739]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":105758739,"title":"Does Removing the Short-sale Constraint Improve Liquidity? Evidence from Hong Kong","translated_title":"","metadata":{"abstract":"The short-sale regulations in Hong Kong provide a unique setting to examine the effects of short- sale constraints on stock market liquidity. Short selling of stocks was prohibited in Hong Kong till 1994. The restrictions were relaxed over a period of eight years in our sample period. We find that removing the short-sale constraints increased the liquidity of lower priced stocks but not higher priced ones. Low priced and high priced stocks had comparable market capitalizations in Hong Kong. However, lower priced stocks had less publicly available information - they had larger adverse selection components in their bid-ask spreads and less sell-side analyst coverage. We also find that the \u0026quot;uptick rule\u0026quot; significantly decreases the market quality. Finally we do not find any evidence that relaxing the short-sale constraints increases total volatilities, upside volatilities, or downside volatilities."},"translated_abstract":"The short-sale regulations in Hong Kong provide a unique setting to examine the effects of short- sale constraints on stock market liquidity. Short selling of stocks was prohibited in Hong Kong till 1994. The restrictions were relaxed over a period of eight years in our sample period. We find that removing the short-sale constraints increased the liquidity of lower priced stocks but not higher priced ones. Low priced and high priced stocks had comparable market capitalizations in Hong Kong. However, lower priced stocks had less publicly available information - they had larger adverse selection components in their bid-ask spreads and less sell-side analyst coverage. We also find that the \u0026quot;uptick rule\u0026quot; significantly decreases the market quality. Finally we do not find any evidence that relaxing the short-sale constraints increases total volatilities, upside volatilities, or downside volatilities.","internal_url":"https://www.academia.edu/105758739/Does_Removing_the_Short_sale_Constraint_Improve_Liquidity_Evidence_from_Hong_Kong","translated_internal_url":"","created_at":"2023-08-19T17:55:05.291-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":24656298,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Does_Removing_the_Short_sale_Constraint_Improve_Liquidity_Evidence_from_Hong_Kong","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":24656298,"first_name":"Jia","middle_initials":null,"last_name":"Hao","page_name":"JiaHao2","domain_name":"independent","created_at":"2015-01-11T07:08:00.159-08:00","display_name":"Jia Hao","url":"https://independent.academia.edu/JiaHao2"},"attachments":[],"research_interests":[{"id":26,"name":"Business","url":"https://www.academia.edu/Documents/in/Business"},{"id":49636,"name":"Adverse Selection","url":"https://www.academia.edu/Documents/in/Adverse_Selection"},{"id":311931,"name":"STOCK EXCHANGE","url":"https://www.academia.edu/Documents/in/STOCK_EXCHANGE"},{"id":3751233,"name":"Market Liquidity","url":"https://www.academia.edu/Documents/in/Market_Liquidity"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="105758738"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/105758738/Research_of_a_Dynamic_Frequency_Spectrum_Assignment_Algorithm_Based_on_Battle_Management_and_Control"><img alt="Research paper thumbnail of Research of a Dynamic Frequency Spectrum Assignment Algorithm Based on Battle Management and Control" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/105758738/Research_of_a_Dynamic_Frequency_Spectrum_Assignment_Algorithm_Based_on_Battle_Management_and_Control">Research of a Dynamic Frequency Spectrum Assignment Algorithm Based on Battle Management and Control</a></div><div class="wp-workCard_item"><span>2010 International Conference on Computational Intelligence and Software Engineering</span><span>, 2010</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Currently, in the military wireless communication, the battle which based on the electromagnetic ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Currently, in the military wireless communication, the battle which based on the electromagnetic environment is very complex. To make sure the army can command the informationization war successfully and win the war finally, using optimized frequency spectrum assignment technology to improve the service efficiency of frequency spectrum resource is become the hot issue in the research of frequency spectrum management domain. Based on battle management and control, in this paper the frequency spectrum assignment problem is abstracted to an assignment problem. The relevant mathematics model of frequency spectrum assignment is built in the paper. The Hungary algorithm is introduced to solve the mathematics model. At last, the logical frequency spectrum assignment scheme is obtained.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="105758738"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="105758738"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 105758738; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=105758738]").text(description); $(".js-view-count[data-work-id=105758738]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 105758738; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='105758738']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 105758738, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=105758738]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":105758738,"title":"Research of a Dynamic Frequency Spectrum Assignment Algorithm Based on Battle Management and Control","translated_title":"","metadata":{"abstract":"Currently, in the military wireless communication, the battle which based on the electromagnetic environment is very complex. To make sure the army can command the informationization war successfully and win the war finally, using optimized frequency spectrum assignment technology to improve the service efficiency of frequency spectrum resource is become the hot issue in the research of frequency spectrum management domain. Based on battle management and control, in this paper the frequency spectrum assignment problem is abstracted to an assignment problem. The relevant mathematics model of frequency spectrum assignment is built in the paper. The Hungary algorithm is introduced to solve the mathematics model. At last, the logical frequency spectrum assignment scheme is obtained.","publisher":"IEEE","publication_date":{"day":null,"month":null,"year":2010,"errors":{}},"publication_name":"2010 International Conference on Computational Intelligence and Software Engineering"},"translated_abstract":"Currently, in the military wireless communication, the battle which based on the electromagnetic environment is very complex. To make sure the army can command the informationization war successfully and win the war finally, using optimized frequency spectrum assignment technology to improve the service efficiency of frequency spectrum resource is become the hot issue in the research of frequency spectrum management domain. Based on battle management and control, in this paper the frequency spectrum assignment problem is abstracted to an assignment problem. The relevant mathematics model of frequency spectrum assignment is built in the paper. The Hungary algorithm is introduced to solve the mathematics model. At last, the logical frequency spectrum assignment scheme is obtained.","internal_url":"https://www.academia.edu/105758738/Research_of_a_Dynamic_Frequency_Spectrum_Assignment_Algorithm_Based_on_Battle_Management_and_Control","translated_internal_url":"","created_at":"2023-08-19T17:55:05.117-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":24656298,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Research_of_a_Dynamic_Frequency_Spectrum_Assignment_Algorithm_Based_on_Battle_Management_and_Control","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":24656298,"first_name":"Jia","middle_initials":null,"last_name":"Hao","page_name":"JiaHao2","domain_name":"independent","created_at":"2015-01-11T07:08:00.159-08:00","display_name":"Jia Hao","url":"https://independent.academia.edu/JiaHao2"},"attachments":[],"research_interests":[{"id":422,"name":"Computer Science","url":"https://www.academia.edu/Documents/in/Computer_Science"},{"id":98566,"name":"Wireless","url":"https://www.academia.edu/Documents/in/Wireless"},{"id":573854,"name":"FREQUENCY ASSIGNMENT","url":"https://www.academia.edu/Documents/in/FREQUENCY_ASSIGNMENT"},{"id":575847,"name":"Assignment Problem","url":"https://www.academia.edu/Documents/in/Assignment_Problem"},{"id":1625072,"name":"Frequency Domain","url":"https://www.academia.edu/Documents/in/Frequency_Domain"},{"id":1995853,"name":"Frequency allocation","url":"https://www.academia.edu/Documents/in/Frequency_allocation"},{"id":2736308,"name":"Frequency spectrum","url":"https://www.academia.edu/Documents/in/Frequency_spectrum"},{"id":3042534,"name":"battle","url":"https://www.academia.edu/Documents/in/battle"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="105758737"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/105758737/The_Patching_Methods_of_the_Bayesian_Network_Data"><img alt="Research paper thumbnail of The Patching Methods of the Bayesian Network Data" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/105758737/The_Patching_Methods_of_the_Bayesian_Network_Data">The Patching Methods of the Bayesian Network Data</a></div><div class="wp-workCard_item"><span>2009 Ninth International Conference on Hybrid Intelligent Systems</span><span>, 2009</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">In this paper, as the issue of Bayesian networks with missing data bring out a repair method of d...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">In this paper, as the issue of Bayesian networks with missing data bring out a repair method of data. This method through a score function to score all nodes, so can obtained for all states points of the Bayesian Network. This is to say all states which belong to Bayesian networks matching degrees can finalized determine the add data&amp;#39;s states. Experiments show¿this method can be learning Bayesian network structure inference or to repair data to make it a complete data it can effectively improve the utilization rate of missing data.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="105758737"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="105758737"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 105758737; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=105758737]").text(description); $(".js-view-count[data-work-id=105758737]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 105758737; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='105758737']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 105758737, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=105758737]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":105758737,"title":"The Patching Methods of the Bayesian Network Data","translated_title":"","metadata":{"abstract":"In this paper, as the issue of Bayesian networks with missing data bring out a repair method of data. This method through a score function to score all nodes, so can obtained for all states points of the Bayesian Network. This is to say all states which belong to Bayesian networks matching degrees can finalized determine the add data\u0026amp;#39;s states. Experiments show¿this method can be learning Bayesian network structure inference or to repair data to make it a complete data it can effectively improve the utilization rate of missing data.","publisher":"IEEE","publication_date":{"day":null,"month":null,"year":2009,"errors":{}},"publication_name":"2009 Ninth International Conference on Hybrid Intelligent Systems"},"translated_abstract":"In this paper, as the issue of Bayesian networks with missing data bring out a repair method of data. This method through a score function to score all nodes, so can obtained for all states points of the Bayesian Network. This is to say all states which belong to Bayesian networks matching degrees can finalized determine the add data\u0026amp;#39;s states. Experiments show¿this method can be learning Bayesian network structure inference or to repair data to make it a complete data it can effectively improve the utilization rate of missing data.","internal_url":"https://www.academia.edu/105758737/The_Patching_Methods_of_the_Bayesian_Network_Data","translated_internal_url":"","created_at":"2023-08-19T17:55:04.935-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":24656298,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"The_Patching_Methods_of_the_Bayesian_Network_Data","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":24656298,"first_name":"Jia","middle_initials":null,"last_name":"Hao","page_name":"JiaHao2","domain_name":"independent","created_at":"2015-01-11T07:08:00.159-08:00","display_name":"Jia Hao","url":"https://independent.academia.edu/JiaHao2"},"attachments":[],"research_interests":[{"id":422,"name":"Computer Science","url":"https://www.academia.edu/Documents/in/Computer_Science"},{"id":18574,"name":"Inference","url":"https://www.academia.edu/Documents/in/Inference"},{"id":121607,"name":"Missing Data","url":"https://www.academia.edu/Documents/in/Missing_Data"},{"id":274599,"name":"Bayesian Network","url":"https://www.academia.edu/Documents/in/Bayesian_Network"},{"id":1032783,"name":"Bayesian Probability","url":"https://www.academia.edu/Documents/in/Bayesian_Probability"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="105758736"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/105758736/Data_transformation_and_attribute_subset_selection_Do_they_help_make_differences_in_software_failure_prediction"><img alt="Research paper thumbnail of Data transformation and attribute subset selection: Do they help make differences in software failure prediction?" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/105758736/Data_transformation_and_attribute_subset_selection_Do_they_help_make_differences_in_software_failure_prediction">Data transformation and attribute subset selection: Do they help make differences in software failure prediction?</a></div><div class="wp-workCard_item"><span>2009 IEEE International Conference on Software Maintenance</span><span>, 2009</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Data transformation and attribute subset selection have been adopted in improving software defect...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Data transformation and attribute subset selection have been adopted in improving software defect/failure prediction methods. However, little consensus was achieved on their effectiveness. This paper reports a comparative study on these two kinds of techniques ...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="105758736"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="105758736"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 105758736; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=105758736]").text(description); $(".js-view-count[data-work-id=105758736]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 105758736; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='105758736']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 105758736, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=105758736]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":105758736,"title":"Data transformation and attribute subset selection: Do they help make differences in software failure prediction?","translated_title":"","metadata":{"abstract":"Data transformation and attribute subset selection have been adopted in improving software defect/failure prediction methods. However, little consensus was achieved on their effectiveness. This paper reports a comparative study on these two kinds of techniques ...","publication_date":{"day":null,"month":null,"year":2009,"errors":{}},"publication_name":"2009 IEEE International Conference on Software Maintenance"},"translated_abstract":"Data transformation and attribute subset selection have been adopted in improving software defect/failure prediction methods. However, little consensus was achieved on their effectiveness. This paper reports a comparative study on these two kinds of techniques ...","internal_url":"https://www.academia.edu/105758736/Data_transformation_and_attribute_subset_selection_Do_they_help_make_differences_in_software_failure_prediction","translated_internal_url":"","created_at":"2023-08-19T17:55:04.789-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":24656298,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Data_transformation_and_attribute_subset_selection_Do_they_help_make_differences_in_software_failure_prediction","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":24656298,"first_name":"Jia","middle_initials":null,"last_name":"Hao","page_name":"JiaHao2","domain_name":"independent","created_at":"2015-01-11T07:08:00.159-08:00","display_name":"Jia Hao","url":"https://independent.academia.edu/JiaHao2"},"attachments":[],"research_interests":[{"id":422,"name":"Computer Science","url":"https://www.academia.edu/Documents/in/Computer_Science"},{"id":1450,"name":"Software Maintenance","url":"https://www.academia.edu/Documents/in/Software_Maintenance"},{"id":2009,"name":"Data Mining","url":"https://www.academia.edu/Documents/in/Data_Mining"},{"id":23890,"name":"Comparative Study","url":"https://www.academia.edu/Documents/in/Comparative_Study"},{"id":45834,"name":"Open Source","url":"https://www.academia.edu/Documents/in/Open_Source"},{"id":53293,"name":"Software","url":"https://www.academia.edu/Documents/in/Software"},{"id":100455,"name":"Open Source Projects","url":"https://www.academia.edu/Documents/in/Open_Source_Projects"},{"id":172642,"name":"Data Transformation","url":"https://www.academia.edu/Documents/in/Data_Transformation"},{"id":547075,"name":"Failure Prediction","url":"https://www.academia.edu/Documents/in/Failure_Prediction"},{"id":1636729,"name":"Attribute Grammars","url":"https://www.academia.edu/Documents/in/Attribute_Grammars"},{"id":2006254,"name":"Subset Selection","url":"https://www.academia.edu/Documents/in/Subset_Selection"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="105758735"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/105758735/_Relationships_between_soil_moisture_and_needle_fall_in_Masson_pine_forests_in_acid_rain_region_of_Chongqing_Southwest_China_"><img alt="Research paper thumbnail of [Relationships between soil moisture and needle-fall in Masson pine forests in acid rain region of Chongqing, Southwest China]" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/105758735/_Relationships_between_soil_moisture_and_needle_fall_in_Masson_pine_forests_in_acid_rain_region_of_Chongqing_Southwest_China_">[Relationships between soil moisture and needle-fall in Masson pine forests in acid rain region of Chongqing, Southwest China]</a></div><div class="wp-workCard_item"><span>Ying yong sheng tai xue bao = The journal of applied ecology / Zhongguo sheng tai xue xue hui, Zhongguo ke xue yuan Shenyang ying yong sheng tai yan jiu suo zhu ban</span><span>, 2012</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">From March 2009 to November 2011, an investigation was conducted on the spatiotemporal variation ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">From March 2009 to November 2011, an investigation was conducted on the spatiotemporal variation of soil moisture and its effects on the needle-fall in Masson pine (Pinus massoniana) forests in acid rain region of Chongqing, Southeast China, with the corresponding soil moisture thresholds determined. No matter the annual precipitation was abundant, normal or less than average, the seasonal variation of soil moisture in the forests could be obviously divided into four periods, i.e., sufficient (before May), descending (from June to July), drought (from August to September), and recovering (from October to November). With increasing soil depth, the soil moisture content increased after an initial decrease, but the difference of the soil moisture content among different soil layers decreased with decreasing annual precipitation. The amount of monthly needle-fall in the forests in growth season was significantly correlated with the water storage in root zone (0-60 cm soil layer), especi...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="105758735"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="105758735"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 105758735; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=105758735]").text(description); $(".js-view-count[data-work-id=105758735]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 105758735; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='105758735']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 105758735, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=105758735]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":105758735,"title":"[Relationships between soil moisture and needle-fall in Masson pine forests in acid rain region of Chongqing, Southwest China]","translated_title":"","metadata":{"abstract":"From March 2009 to November 2011, an investigation was conducted on the spatiotemporal variation of soil moisture and its effects on the needle-fall in Masson pine (Pinus massoniana) forests in acid rain region of Chongqing, Southeast China, with the corresponding soil moisture thresholds determined. No matter the annual precipitation was abundant, normal or less than average, the seasonal variation of soil moisture in the forests could be obviously divided into four periods, i.e., sufficient (before May), descending (from June to July), drought (from August to September), and recovering (from October to November). With increasing soil depth, the soil moisture content increased after an initial decrease, but the difference of the soil moisture content among different soil layers decreased with decreasing annual precipitation. The amount of monthly needle-fall in the forests in growth season was significantly correlated with the water storage in root zone (0-60 cm soil layer), especi...","publication_date":{"day":null,"month":null,"year":2012,"errors":{}},"publication_name":"Ying yong sheng tai xue bao = The journal of applied ecology / Zhongguo sheng tai xue xue hui, Zhongguo ke xue yuan Shenyang ying yong sheng tai yan jiu suo zhu ban"},"translated_abstract":"From March 2009 to November 2011, an investigation was conducted on the spatiotemporal variation of soil moisture and its effects on the needle-fall in Masson pine (Pinus massoniana) forests in acid rain region of Chongqing, Southeast China, with the corresponding soil moisture thresholds determined. No matter the annual precipitation was abundant, normal or less than average, the seasonal variation of soil moisture in the forests could be obviously divided into four periods, i.e., sufficient (before May), descending (from June to July), drought (from August to September), and recovering (from October to November). With increasing soil depth, the soil moisture content increased after an initial decrease, but the difference of the soil moisture content among different soil layers decreased with decreasing annual precipitation. The amount of monthly needle-fall in the forests in growth season was significantly correlated with the water storage in root zone (0-60 cm soil layer), especi...","internal_url":"https://www.academia.edu/105758735/_Relationships_between_soil_moisture_and_needle_fall_in_Masson_pine_forests_in_acid_rain_region_of_Chongqing_Southwest_China_","translated_internal_url":"","created_at":"2023-08-19T17:55:04.614-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":24656298,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"_Relationships_between_soil_moisture_and_needle_fall_in_Masson_pine_forests_in_acid_rain_region_of_Chongqing_Southwest_China_","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":24656298,"first_name":"Jia","middle_initials":null,"last_name":"Hao","page_name":"JiaHao2","domain_name":"independent","created_at":"2015-01-11T07:08:00.159-08:00","display_name":"Jia Hao","url":"https://independent.academia.edu/JiaHao2"},"attachments":[],"research_interests":[{"id":402,"name":"Environmental Science","url":"https://www.academia.edu/Documents/in/Environmental_Science"},{"id":1605,"name":"Soil","url":"https://www.academia.edu/Documents/in/Soil"},{"id":2215,"name":"Water","url":"https://www.academia.edu/Documents/in/Water"},{"id":12108,"name":"China","url":"https://www.academia.edu/Documents/in/China"},{"id":26177,"name":"Acid Rain","url":"https://www.academia.edu/Documents/in/Acid_Rain"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":28120,"name":"Spatio Temporal Analysis","url":"https://www.academia.edu/Documents/in/Spatio_Temporal_Analysis"},{"id":133176,"name":"Moisture","url":"https://www.academia.edu/Documents/in/Moisture"},{"id":188993,"name":"Litter","url":"https://www.academia.edu/Documents/in/Litter"},{"id":291658,"name":"Precipitation","url":"https://www.academia.edu/Documents/in/Precipitation"},{"id":359474,"name":"Pinus","url":"https://www.academia.edu/Documents/in/Pinus"},{"id":373754,"name":"Ecosystem","url":"https://www.academia.edu/Documents/in/Ecosystem"},{"id":649451,"name":"Seasons","url":"https://www.academia.edu/Documents/in/Seasons"},{"id":845678,"name":"Water Content","url":"https://www.academia.edu/Documents/in/Water_Content"},{"id":1222799,"name":"Soil Water","url":"https://www.academia.edu/Documents/in/Soil_Water"},{"id":1905343,"name":"Plant Leaves","url":"https://www.academia.edu/Documents/in/Plant_Leaves"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="105758734"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/105758734/EF4_knockout_E_coli_cells_exhibit_lower_levels_of_cellular_biosynthesis_under_acidic_stress"><img alt="Research paper thumbnail of EF4 knockout E. coli cells exhibit lower levels of cellular biosynthesis under acidic stress" class="work-thumbnail" src="https://attachments.academia-assets.com/105137861/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/105758734/EF4_knockout_E_coli_cells_exhibit_lower_levels_of_cellular_biosynthesis_under_acidic_stress">EF4 knockout E. coli cells exhibit lower levels of cellular biosynthesis under acidic stress</a></div><div class="wp-workCard_item"><span>Protein & cell</span><span>, 2014</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="8c4cbdcb06296a5512a336721bfdd7b2" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":105137861,"asset_id":105758734,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/105137861/download_file?st=MTczMjczOTk3NCw4LjIyMi4yMDguMTQ2&st=MTczMjczOTk3NCw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="105758734"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="105758734"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 105758734; 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$(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="105758733"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" rel="nofollow" href="https://www.academia.edu/105758733/Analysis_on_Crystal_Structure_of_7%C3%85_Halloysite"><img alt="Research paper thumbnail of Analysis on Crystal Structure of 7Å-Halloysite" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" rel="nofollow" href="https://www.academia.edu/105758733/Analysis_on_Crystal_Structure_of_7%C3%85_Halloysite">Analysis on Crystal Structure of 7Å-Halloysite</a></div><div class="wp-workCard_item"><span>Advanced Materials Research</span><span>, 2011</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Precise crystal structure determination of the Halloysite is extremely challenging because Halloy...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Precise crystal structure determination of the Halloysite is extremely challenging because Halloysite naturally occurs as small cylinders and the ideal single crystal sample is unavailable. The up-to-date ICSD does not have the cystal structure data of Halloysite. With the development of computer science and technologies, the X-ray powder diffraction technologies have been commonly used in the crystal structure determination. This paper attempts to obtain the refined crystal structure of Halloysite by using the X-ray powder diffraction, on the assumption that the Halloysite and Kaolinite have a similar cystal structure, that is, the 1:1 phyllosilicates structure. The structure refinement program Rietica 2010 is used in this paper.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="105758733"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="105758733"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 105758733; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=105758733]").text(description); $(".js-view-count[data-work-id=105758733]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 105758733; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='105758733']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 105758733, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=105758733]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":105758733,"title":"Analysis on Crystal Structure of 7Å-Halloysite","translated_title":"","metadata":{"abstract":"Precise crystal structure determination of the Halloysite is extremely challenging because Halloysite naturally occurs as small cylinders and the ideal single crystal sample is unavailable. The up-to-date ICSD does not have the cystal structure data of Halloysite. With the development of computer science and technologies, the X-ray powder diffraction technologies have been commonly used in the crystal structure determination. This paper attempts to obtain the refined crystal structure of Halloysite by using the X-ray powder diffraction, on the assumption that the Halloysite and Kaolinite have a similar cystal structure, that is, the 1:1 phyllosilicates structure. The structure refinement program Rietica 2010 is used in this paper.","publisher":"Trans Tech Publications","publication_date":{"day":null,"month":null,"year":2011,"errors":{}},"publication_name":"Advanced Materials Research"},"translated_abstract":"Precise crystal structure determination of the Halloysite is extremely challenging because Halloysite naturally occurs as small cylinders and the ideal single crystal sample is unavailable. The up-to-date ICSD does not have the cystal structure data of Halloysite. With the development of computer science and technologies, the X-ray powder diffraction technologies have been commonly used in the crystal structure determination. This paper attempts to obtain the refined crystal structure of Halloysite by using the X-ray powder diffraction, on the assumption that the Halloysite and Kaolinite have a similar cystal structure, that is, the 1:1 phyllosilicates structure. The structure refinement program Rietica 2010 is used in this paper.","internal_url":"https://www.academia.edu/105758733/Analysis_on_Crystal_Structure_of_7%C3%85_Halloysite","translated_internal_url":"","created_at":"2023-08-19T17:55:04.284-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":24656298,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Analysis_on_Crystal_Structure_of_7Å_Halloysite","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":24656298,"first_name":"Jia","middle_initials":null,"last_name":"Hao","page_name":"JiaHao2","domain_name":"independent","created_at":"2015-01-11T07:08:00.159-08:00","display_name":"Jia Hao","url":"https://independent.academia.edu/JiaHao2"},"attachments":[],"research_interests":[{"id":511,"name":"Materials Science","url":"https://www.academia.edu/Documents/in/Materials_Science"},{"id":21927,"name":"Advanced Materials","url":"https://www.academia.edu/Documents/in/Advanced_Materials"},{"id":50630,"name":"Crystal structure","url":"https://www.academia.edu/Documents/in/Crystal_structure"},{"id":165106,"name":"Diffraction","url":"https://www.academia.edu/Documents/in/Diffraction"},{"id":2443168,"name":"Halloysite","url":"https://www.academia.edu/Documents/in/Halloysite"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="105758732"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/105758732/Efficient_access_to_isomeric_2_3_dihydroxy_lupanes_first_synthesis_of_alphitolic_acid"><img alt="Research paper thumbnail of Efficient access to isomeric 2,3-dihydroxy lupanes: first synthesis of alphitolic acid" class="work-thumbnail" src="https://attachments.academia-assets.com/105137875/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/105758732/Efficient_access_to_isomeric_2_3_dihydroxy_lupanes_first_synthesis_of_alphitolic_acid">Efficient access to isomeric 2,3-dihydroxy lupanes: first synthesis of alphitolic acid</a></div><div class="wp-workCard_item"><span>Tetrahedron</span><span>, 2009</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="077b881fd50d56317aa40faf93540254" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":105137875,"asset_id":105758732,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/105137875/download_file?st=MTczMjczOTk3NCw4LjIyMi4yMDguMTQ2&st=MTczMjczOTk3NCw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="105758732"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="105758732"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 105758732; 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The synthesized triterpenes 3-10 were evaluated for their inhibitory activity against rabbit muscle GPa (RMGPa), and some of them exhibited moderate inhibitory activity against RMGPa.","publication_date":{"day":null,"month":null,"year":2009,"errors":{}},"publication_name":"Tetrahedron","grobid_abstract_attachment_id":105137875},"translated_abstract":null,"internal_url":"https://www.academia.edu/105758732/Efficient_access_to_isomeric_2_3_dihydroxy_lupanes_first_synthesis_of_alphitolic_acid","translated_internal_url":"","created_at":"2023-08-19T17:55:04.033-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":24656298,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":105137875,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/105137875/thumbnails/1.jpg","file_name":"j.tet.2009.07.04720230820-1-mz1a59.pdf","download_url":"https://www.academia.edu/attachments/105137875/download_file?st=MTczMjczOTk3NCw4LjIyMi4yMDguMTQ2&st=MTczMjczOTk3NCw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Efficient_access_to_isomeric_2_3_dihydro.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/105137875/j.tet.2009.07.04720230820-1-mz1a59-libre.pdf?1692497763=\u0026response-content-disposition=attachment%3B+filename%3DEfficient_access_to_isomeric_2_3_dihydro.pdf\u0026Expires=1732743574\u0026Signature=XK-mX-vtvR215UMN-9pby4UGoIOzgmSRFATAOJYTv2-EzqKHvOEtjkrw~A6NaJIJR9FFeqh6SoSecRCiCAIgZISqDTAt55lXDmTi3EAYTX5tWXu1dQ6Rgr938X9AGdNEzuQfOFISbSCgkUrXVP~JvWaaChx4OJHQmifen27fyrlGo6WyV52j8bhvca1qTTWx3vMlmgj56XbLNePzFQX8NIB~eY1zsCfsuUreB-LMV7~ic1j1NkqWNeiLtrTIk3AQTcT3D5hE1bHvQWOC85GyoPetPcnP76bp-5CZNCem7bsNchH3yLgh5aF0ZvOYkgxWCM9Tob20vTOgWB~eX~obrA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Efficient_access_to_isomeric_2_3_dihydroxy_lupanes_first_synthesis_of_alphitolic_acid","translated_slug":"","page_count":10,"language":"en","content_type":"Work","owner":{"id":24656298,"first_name":"Jia","middle_initials":null,"last_name":"Hao","page_name":"JiaHao2","domain_name":"independent","created_at":"2015-01-11T07:08:00.159-08:00","display_name":"Jia Hao","url":"https://independent.academia.edu/JiaHao2"},"attachments":[{"id":105137875,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/105137875/thumbnails/1.jpg","file_name":"j.tet.2009.07.04720230820-1-mz1a59.pdf","download_url":"https://www.academia.edu/attachments/105137875/download_file?st=MTczMjczOTk3NCw4LjIyMi4yMDguMTQ2&st=MTczMjczOTk3NCw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Efficient_access_to_isomeric_2_3_dihydro.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/105137875/j.tet.2009.07.04720230820-1-mz1a59-libre.pdf?1692497763=\u0026response-content-disposition=attachment%3B+filename%3DEfficient_access_to_isomeric_2_3_dihydro.pdf\u0026Expires=1732743574\u0026Signature=XK-mX-vtvR215UMN-9pby4UGoIOzgmSRFATAOJYTv2-EzqKHvOEtjkrw~A6NaJIJR9FFeqh6SoSecRCiCAIgZISqDTAt55lXDmTi3EAYTX5tWXu1dQ6Rgr938X9AGdNEzuQfOFISbSCgkUrXVP~JvWaaChx4OJHQmifen27fyrlGo6WyV52j8bhvca1qTTWx3vMlmgj56XbLNePzFQX8NIB~eY1zsCfsuUreB-LMV7~ic1j1NkqWNeiLtrTIk3AQTcT3D5hE1bHvQWOC85GyoPetPcnP76bp-5CZNCem7bsNchH3yLgh5aF0ZvOYkgxWCM9Tob20vTOgWB~eX~obrA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":523,"name":"Chemistry","url":"https://www.academia.edu/Documents/in/Chemistry"},{"id":531,"name":"Organic Chemistry","url":"https://www.academia.edu/Documents/in/Organic_Chemistry"},{"id":242013,"name":"TERPENE","url":"https://www.academia.edu/Documents/in/TERPENE"},{"id":435190,"name":"Tetrahedron","url":"https://www.academia.edu/Documents/in/Tetrahedron"},{"id":1152821,"name":"Chemical Synthesis","url":"https://www.academia.edu/Documents/in/Chemical_Synthesis"},{"id":2281154,"name":"Terpenoid","url":"https://www.academia.edu/Documents/in/Terpenoid"}],"urls":[{"id":33510680,"url":"https://api.elsevier.com/content/article/PII:S0040402009011090?httpAccept=text/xml"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="105758731"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/105758731/Assessment_of_Cancer_Pain_Management_Knowledge_in_Southwest_China_A_Survey_of_259_Physicians_from_Small_City_and_County_Hospitals"><img alt="Research paper thumbnail of Assessment of Cancer Pain Management Knowledge in Southwest China: A Survey of 259 Physicians from Small City and County Hospitals" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/105758731/Assessment_of_Cancer_Pain_Management_Knowledge_in_Southwest_China_A_Survey_of_259_Physicians_from_Small_City_and_County_Hospitals">Assessment of Cancer Pain Management Knowledge in Southwest China: A Survey of 259 Physicians from Small City and County Hospitals</a></div><div class="wp-workCard_item"><span>Journal of Palliative Medicine</span><span>, 2013</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Pain management is a critical issue in the care of cancer patients in China, especially in small ...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Pain management is a critical issue in the care of cancer patients in China, especially in small city and county hospitals in southwest China. The study intended to determine Chinese physicians&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;#39; competence in cancer pain management and to assess their opinions on barriers to optimal pain management. A questionnaire on pain management was given to 259 fellows after their general orientation meeting at a tertiary teaching hospital. The questionnaire was adapted from an earlier study by the Eastern Cooperative Oncology Group (ECOG). The majority of the fellows believed that 70% of cancer patients suffer pain. Nearly 90% (224/259) indicated that their training in cancer pain management was poor. The fellows stated that concern about morphine addiction was the primary reason they hesitated to prescribe opioids, and they identified inadequate assessment of cancer pain as the most significant barrier to optimal management of cancer pain. The study reflects to some extent the state of pain management in hospitals in southwest China. Medical students and physicians in China need improved pain management education.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="105758731"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="105758731"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 105758731; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=105758731]").text(description); $(".js-view-count[data-work-id=105758731]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 105758731; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='105758731']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 105758731, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=105758731]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":105758731,"title":"Assessment of Cancer Pain Management Knowledge in Southwest China: A Survey of 259 Physicians from Small City and County Hospitals","translated_title":"","metadata":{"abstract":"Pain management is a critical issue in the care of cancer patients in China, especially in small city and county hospitals in southwest China. The study intended to determine Chinese physicians\u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;#39; competence in cancer pain management and to assess their opinions on barriers to optimal pain management. A questionnaire on pain management was given to 259 fellows after their general orientation meeting at a tertiary teaching hospital. The questionnaire was adapted from an earlier study by the Eastern Cooperative Oncology Group (ECOG). The majority of the fellows believed that 70% of cancer patients suffer pain. Nearly 90% (224/259) indicated that their training in cancer pain management was poor. The fellows stated that concern about morphine addiction was the primary reason they hesitated to prescribe opioids, and they identified inadequate assessment of cancer pain as the most significant barrier to optimal management of cancer pain. The study reflects to some extent the state of pain management in hospitals in southwest China. Medical students and physicians in China need improved pain management education.","publisher":"Mary Ann Liebert Inc","publication_date":{"day":null,"month":null,"year":2013,"errors":{}},"publication_name":"Journal of Palliative Medicine"},"translated_abstract":"Pain management is a critical issue in the care of cancer patients in China, especially in small city and county hospitals in southwest China. The study intended to determine Chinese physicians\u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;#39; competence in cancer pain management and to assess their opinions on barriers to optimal pain management. A questionnaire on pain management was given to 259 fellows after their general orientation meeting at a tertiary teaching hospital. The questionnaire was adapted from an earlier study by the Eastern Cooperative Oncology Group (ECOG). The majority of the fellows believed that 70% of cancer patients suffer pain. Nearly 90% (224/259) indicated that their training in cancer pain management was poor. The fellows stated that concern about morphine addiction was the primary reason they hesitated to prescribe opioids, and they identified inadequate assessment of cancer pain as the most significant barrier to optimal management of cancer pain. The study reflects to some extent the state of pain management in hospitals in southwest China. Medical students and physicians in China need improved pain management education.","internal_url":"https://www.academia.edu/105758731/Assessment_of_Cancer_Pain_Management_Knowledge_in_Southwest_China_A_Survey_of_259_Physicians_from_Small_City_and_County_Hospitals","translated_internal_url":"","created_at":"2023-08-19T17:55:03.878-07:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":24656298,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Assessment_of_Cancer_Pain_Management_Knowledge_in_Southwest_China_A_Survey_of_259_Physicians_from_Small_City_and_County_Hospitals","translated_slug":"","page_count":null,"language":"en","content_type":"Work","owner":{"id":24656298,"first_name":"Jia","middle_initials":null,"last_name":"Hao","page_name":"JiaHao2","domain_name":"independent","created_at":"2015-01-11T07:08:00.159-08:00","display_name":"Jia Hao","url":"https://independent.academia.edu/JiaHao2"},"attachments":[],"research_interests":[{"id":588,"name":"Nursing","url":"https://www.academia.edu/Documents/in/Nursing"},{"id":4376,"name":"Family Medicine","url":"https://www.academia.edu/Documents/in/Family_Medicine"},{"id":6021,"name":"Cancer","url":"https://www.academia.edu/Documents/in/Cancer"},{"id":12108,"name":"China","url":"https://www.academia.edu/Documents/in/China"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":28023,"name":"Palliative Medicine","url":"https://www.academia.edu/Documents/in/Palliative_Medicine"},{"id":40165,"name":"Pain Management","url":"https://www.academia.edu/Documents/in/Pain_Management"},{"id":72845,"name":"Cancer pain","url":"https://www.academia.edu/Documents/in/Cancer_pain"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences"},{"id":327850,"name":"Questionnaires","url":"https://www.academia.edu/Documents/in/Questionnaires"},{"id":410370,"name":"Public health systems and services research","url":"https://www.academia.edu/Documents/in/Public_health_systems_and_services_research-1"},{"id":469018,"name":"Neoplasms","url":"https://www.academia.edu/Documents/in/Neoplasms"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="105758730"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/105758730/Down_regulation_of_miR_106b_suppresses_the_growth_of_human_glioma_cells"><img alt="Research paper thumbnail of Down-regulation of miR-106b suppresses the growth of human glioma cells" class="work-thumbnail" src="https://attachments.academia-assets.com/105137871/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/105758730/Down_regulation_of_miR_106b_suppresses_the_growth_of_human_glioma_cells">Down-regulation of miR-106b suppresses the growth of human glioma cells</a></div><div class="wp-workCard_item"><span>Journal of Neuro-Oncology</span><span>, 2013</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="6fa4057dfc964a4555f15a4af144dbbd" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":105137871,"asset_id":105758730,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/105137871/download_file?st=MTczMjczOTk3NCw4LjIyMi4yMDguMTQ2&st=MTczMjczOTk3NCw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="105758730"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="105758730"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 105758730; 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However, the precise role of each microRNAs (miRNAs) in the cluster is not yet clear. In the present study, we examined the expression of miR-106b in glioma samples and a tissue microarray by real-time PCR and in situ hybridization (ISH), respectively, finding that miR-106b is overexpressed in the majority of gliomas. Meanwhile, the expression of miR-106b was positively correlated with tumor grade (p \\ 0.05). The transfection of a miR-106b anti-sense oligonucleotide (ASON) into three human glioma cell lines (U251, LN229 and TJ905) suppressed the proliferation of these cells. Moreover, the growth of xenograft tumors in nude mice treated with miR-106b ASON was significantly impaired. A bioinformatics analysis predicted that RBL2 may be the target of miR-106b, and dual-luciferase reporter assays identified RBL2, but not RB1 or RBL1, as a target of miR-106b. These results suggest that miR-106b facilitates glioma cell growth by promoting cell cycle progression through the negative regulation of RBL2.","publication_date":{"day":null,"month":null,"year":2013,"errors":{}},"publication_name":"Journal of 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hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/105758729/Synthesis_of_3_Deoxypentacyclic_Triterpene_Derivatives_as_Inhibitors_of_Glycogen_Phosphorylase"><img alt="Research paper thumbnail of Synthesis of 3-Deoxypentacyclic Triterpene Derivatives as Inhibitors of Glycogen Phosphorylase" class="work-thumbnail" src="https://attachments.academia-assets.com/105137880/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/105758729/Synthesis_of_3_Deoxypentacyclic_Triterpene_Derivatives_as_Inhibitors_of_Glycogen_Phosphorylase">Synthesis of 3-Deoxypentacyclic Triterpene Derivatives as Inhibitors of Glycogen Phosphorylase</a></div><div class="wp-workCard_item"><span>Journal of Natural Products</span><span>, 2009</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="bcd73e22bcd493188c0d181b3cc161a3" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":105137880,"asset_id":105758729,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/105137880/download_file?st=MTczMjczOTk3NCw4LjIyMi4yMDguMTQ2&st=MTczMjczOTk3NCw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="105758729"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span 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