Kaken Pharmaceutical and Numab Therapeutics collaborate on inflammatory bowel disease treatment

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class="clearfix"></div> <div class="col-md-12 pt text"> <p class="bold"> Numab to receive R&D funding for the preclinical development of ND081; Kaken Pharmaceutical receives an option to in-license ND081 in certain Asian territories in exchange for funding global development up to clinical POC </p> <div class="row"> <div class="col-md-12 col-centered"> <img src="/uploads/articles/hfthfjtg-25221.jpg" class="thumbnail" alt="Image credit: Freepik" /> <p>Image credit: Freepik</p> </div> </div> <div id="page1"> <p align="left">Numab Therapeutics AG, a clinical stage biotechnology company advancing a proprietary pipeline of multi-specific antibodies in immunology and oncology, and Kaken Pharmaceutical Co., Ltd., an R&D driven pharmaceutical company in Japan, announced a new collaboration and option agreement to develop ND081, a potential first-in-class multi-specific antibody for the treatment of inflammatory bowel disease (IBD).</p> <p align="left">Under the terms of the agreement, Kaken has obtained an option to acquire commercial rights to ND081 for certain key Asian territories in exchange for funding preclinical and clinical development up to Phase 2a proof of concept. Numab will receive approximately CHF 13 million as an upfront payment and will be the main executing party of preclinical and clinical development.</p> <p align="left">“We are joining forces with Kaken to advance one of our multi-specific programs to the clinic as a continuation of our regional partnering strategy aimed at utilizing Numab’s unique proprietary λ-Cap<sup>TM</sup> and MATCH<sup>TM</sup> technology platforms,” said David Urech, Ph.D., Founder and Chief Executive Officer of Numab Therapeutics.</p> <p align="left">“This partnership in IBD represents a validated approach for both Numab and Kaken and is built out of a strong relationship that we established from our prior collaboration on NM26, an investigational first-in-class bi-specific antibody for the treatment of atopic dermatitis, which led to an asset spin out into Yellow Jersey Therapeutics and its subsequent acquisition by Johnson & Johnson for $1.25 billion in May 2024” adds David Urech.</p> <p align="justify">“By leveraging our research and development capabilities and Numab's unique expertise in multi-specifics, we will do our utmost to develop innovative new drugs for IBD,” said Hiroyuki Horiuchi, President and Representative Director of Kaken Pharmaceutical.</p> </div> <ins class="aso-zone" data-zone="84574"></ins><script data-cfasync="false" async="async" type="text/javascript" src="https://media.aso1.net/js/code.min.js"></script>  <div class="row"> <div class="col-md-12 gray"> <h4>Sign up for the editor pick and get articles like this delivered right to your inbox.</h4> <form method="post" role="form" name="editorPickForm" action="/article-editors-pick-data" class="form-horizontal"> <div class="col-md-5"> <img src="/cms-images/editor-picks-E-mailer.jpg" class="img-responsive" alt="Editors Pick" /> </div> <div class="col-md-7"> <div class="form-group"> <label class="control-label" for="ename">Name<span class="required"> * </span></label> <input type="text" name="editorPickForm[name]" class=" form-control" id="ename" required> </div> <div class="form-group"> <label class="control-label" for="eemail">Email<span class="required"> * </span></label> <input type="email" name="editorPickForm[email]" class=" form-control" id="eemail" required> </div> <div class="form-group"> <label class="control-label" for="ecountry">Country<span class="required"> * </span></label> <input type="text" name="editorPickForm[country]" class=" form-control" id="ecountry" required> </div> <div class="form-group"> <label class="control-label" for="eorganisation">Organisation<span class="required"> * </span></label> <input type="text" name="editorPickForm[organisation]" class=" form-control" id="eorganisation" required> </div> <div class="form-group"> <label class="control-label" for="ecountry-code">Contact Number<span class="required"> * </span></label> <input type="text" name="editorPickForm[contact]" class=" form-control col-md-2" id="econtact" required> <span class="help-block">+Country Code-Phone Number(xxx-xxxxxxx)</span> </div> <button type="submit" class="btn btn-success">Submit</button> </div> </form><br/> </div> </div><br/>  <div class="row"> <div class="col-md-12 gray"> <h3>Comments</h3> <form role="form" name="commentForm" id="commentForm0" ng-controller="SiteCommentController" ng-submit="submitComment()" ng-model="commentAction" ng-init="commentAction='/comment-handle/'"> <div class="alert alert-success alert-dismissable" id="comment-success-box-0" style="display: none;"> <a href="#" class="close" data-dismiss="alert" aria-label="close">×</a> <h3>Thank You</h3> <strong>Your comment has been submitted for approval.</strong><br/> Please note that comments are moderated and are generally published if they are on-topic and not abusive. </div> <div class="form-group"> <label class="sr-only" for="comment-message_0">Comment</label> <textarea name="comment" placeholder="Enter your comment here" class="contact-message form-control" id="comment-message_0" ng-model="commentFormData.comment"></textarea> </div> <div class="alert alert-danger alert-dismissable ng-cloak" ng-if="sessionError != '0'"> <a href="#" class="close" data-dismiss="alert" aria-label="close">×</a> Your session has been expired. 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function(event) { this.value = this.value.toLowerCase(); $('#enquiry-email-error').hide(); }); $('#save-enquiry-btn').on('click', function(event) { saveEnquiry(this); }); $('#enquiryForm').on('keyup', '#name, #email, #contact, #message', function(event) { $('#enquiry-error').hide(); }); $("#contact").on('keydown', function (e) { allNumeric(e); }); $('#account-email').on('blur', function(event) { isEmailExist(); }); $('#account-email').on('keyup', function(event) { this.value = this.value.toLowerCase(); $('#account-email-error').hide(); }); $('#loginForm').on('keydown', '#login-email, #login-password', function(event) { $('#login-email-error').hide(); $('#login-password-error').hide(); }); $("#registrationForm").on('keydown', '#account-confirm-password, #account-password, #account-firstName, #account-lastName', function (e) { $('#account-password-error').hide(); $('#account-pass-error').hide(); $('#account-firstName-error').hide(); $('#account-lastName-error').hide(); }); $('#forgotPasswordForm').on('keydown', '#forgot-pass-email', function(event) { $('#forgot-pass-email-error').hide(); }); }); function validatePassword() { var password = $("#account-password").val(); var confirmPassword = $("#account-confirm-password").val(); if(password == '') { $('#account-pass-error').text("Password should not be empty.").show(); return false; } else { if(password.length < passwrodLength) { $('#account-pass-error').text("Your password must be at least " + passwrodLength + " characters long.").show(); return false; } } if(confirmPassword == '') { $('#account-password-error').text("Confirm Password should not be empty.").show(); return false; } else { if(confirmPassword.length < passwrodLength) { $('#account-password-error').text("Your password must be at least " + passwrodLength + " characters long.").show(); return false; } } if (password != confirmPassword) { $('#account-password-error').text("'Password' and 'Confirm Password' must match.").show(); return false; } return true; } function validateRegistration() { var nameRegex = /^[a-zA-Z]+$/; if($("#account-firstName").val() == '') { $('#account-firstName-error').text("First name should not be empty.").show(); return false; } else { if (!$("#account-firstName").val().match(nameRegex)) { $('#account-firstName-error').text("Please enter a valid first name.").show(); return false; } } if($("#account-lastName").val() == '') { $('#account-lastName-error').text("Last name should not be empty.").show(); return false; } else { if (!$("#account-lastName").val().match(nameRegex)) { $('#account-lastName-error').text("Please enter a valid last name.").show(); return false; } } if($("#account-email").val() == '') { $('#account-email-error').text("Email address should not be empty.").show(); return false; } else { if(!validateEmail($("#account-email").val())) { $('#account-email-error').text("Please enter a valid email address.").show(); return false; } //isEmailExist(); var emailStatus = $('#is-email-exist').val(); if(emailStatus == '1') { $('#account-email-error').text('That username is taken. Try another one.').show(); return false; } } return validatePassword(); } function validateLogin() { if($("#login-email").val() == '') { $('#login-email-error').text("Email address should not be empty.").show(); return false; } else { if(!validateEmail($("#login-email").val())) { $('#login-email-error').text("Please enter a valid email address.").show(); return false; } } if($("#login-password").val() == '') { $('#login-password-error').text("Password should not be empty.").show(); return false; } else { if($("#login-password").val().length < passwrodLength) { $('#login-password-error').text("Your password must be at least " + passwrodLength + " characters long.").show(); return false; } } return true; } function validateForgotPassword() { if($("#forgot-pass-email").val() == '') { $('#forgot-pass-email-error').text("Email address should not be empty.").show(); return false; } else { if(!validateEmail($("#forgot-pass-email").val())) { $('#forgot-pass-email-error').text("Please enter a valid email address.").show(); return false; } } return true; } function isEmailExist() { var email = $('#account-email').val(); $('#is-email-exist').val(0); $.post("/email-validator/", {'email':email}, function(data) { if(data.response.isEmailExist == true) { $('#is-email-exist').val(1); $('#account-email-error').text('That username is taken. Try another one.').show(); } },'json'); } function validateNewsletter() { if($("#nl-email").val() == '') { $('#nl-email-error').text("Email address should not be empty.").show(); return false; } else { if(!validateEmail($("#nl-email").val())) { $('#nl-email-error').text("Please enter a valid email address.").show(); return false; } } return true; } </script> <script src="/bundles/interlinksapp/assets/global/plugins/angularjs/angular.min.js" type="text/javascript"></script> <script src="/bundles/interlinksapp/assets/global/plugins/angularjs/angular-route.min.js" type="text/javascript"></script> <script src="/bundles/interlinksapp/app/app-asia/js/SitePollController.js?20241127133442863642" type="text/javascript"></script> <script> (function(d, s, id) { var js, fjs = d.getElementsByTagName(s)[0]; if (d.getElementById(id)) return; js = d.createElement(s); js.id = id; js.src = "//connect.facebook.net/en_GB/sdk.js#xfbml=1&version=v2.9&appId=220402091798716"; fjs.parentNode.insertBefore(js, fjs); }(document, 'script', 'facebook-jssdk')); </script> <script src="//platform.twitter.com/widgets.js"></script> <script src="https://apis.google.com/js/platform.js" async defer></script> <script src="//platform.linkedin.com/in.js" type="text/javascript"> lang: en_US</script> <script src="/bundles/interlinksapp/app/app-asia/js/SiteCommentController.js?20241127133442863651" type="text/javascript"></script> <script src="/bundles/interlinksapp/assets/global/plugins/text-to-speech/articulate.min.js" type="text/javascript"></script> <script type="text/javascript"> $(function() { //This code for article page toggle view comment box $('.toggle').click(function(event) { $('#credits').toggleClass('hidden show'); }); $('.clogin-button').click(function(event) { $('#myModal').modal('show'); $('#login-tab').trigger('click'); }); $('.cregister-button').click(function(event) { $('#myModal').modal('show'); $('#registration').trigger('click'); }); //Text to speech script Start var selector = $('#page1'); $('#play-button').click(function(event) { // Sets the pitch of the speaking voice; // default = 1.0; range = [0 - 2] selector.articulate('pitch', 2); // Sets the rate of the speaking voice // default = 1.1; range = [0.1 - 10] selector.articulate('rate', 0.8); selector.articulate('speak'); $('#play-button').parent().hide(); $('#resume-button').parent().hide(); $('#pause-button').parent().show(); $('#stop-button').parent().show(); }); $('#pause-button').click(function(event) { selector.articulate('pause'); $('#resume-button').parent().show(); $('#pause-button').parent().hide(); }); $('#stop-button').click(function(event) { selector.articulate('stop'); $('#play-button').parent().show(); $('#resume-button').parent().hide(); $('#pause-button').parent().hide(); }); $('#resume-button').click(function(event) { // Sets the pitch of the speaking voice; // default = 1.0; range = [0 - 2] selector.articulate('pitch', 2); // Sets the rate of the speaking voice // default = 1.1; range = [0.1 - 10] selector.articulate('rate', 0.8); selector.articulate('resume'); $('#resume-button').parent().hide(); $('#pause-button').parent().show(); }); //Text to speech script End }); </script> <script> function speak(obj) { $(obj).articulate('speak'); //$(obj).articulate('rate', 0.5); }; function pause() { $().articulate('pause'); }; function resume() { $().articulate('resume'); }; function stop() { $().articulate('stop'); }; </script>  <script> (function(i,s,o,g,r,a,m){i['GoogleAnalyticsObject']=r;i[r]=i[r]||function(){ (i[r].q=i[r].q||[]).push(arguments)},i[r].l=1*new Date();a=s.createElement(o), m=s.getElementsByTagName(o)[0];a.async=1;a.src=g;m.parentNode.insertBefore(a,m) })(window,document,'script','https://www.google-analytics.com/analytics.js','ga'); ga('create', 'UA-58743002-1', 'auto'); ga('send', 'pageview'); </script>  <script async src="https://www.googletagmanager.com/gtag/js?id=G-CWX6K6L4H3"></script> <script> window.dataLayer = window.dataLayer || []; function gtag(){dataLayer.push(arguments);} gtag('js', new Date()); gtag('config', 'G-CWX6K6L4H3'); </script>  <script src="https://www.google.com/recaptcha/api.js" async defer></script> <script> var recaptcha_response = ''; function submitUserForm() { if(recaptcha_response.length == 0) { document.getElementById('g-recaptcha-error').innerHTML = '<span style="color:red;">This field is required.</span>'; return false; } return true; } function verifyCaptcha(token) { recaptcha_response = token; document.getElementById('g-recaptcha-error').innerHTML = ''; } </script>  </body> </html>

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