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fl-builder-content-423 fl-builder-content-primary fl-builder-global-templates-locked" data-post-id="423"><div class="fl-row fl-row-fixed-width fl-row-bg-none fl-node-0f456nolpxb9 fl-row-default-height fl-row-align-center" data-node="0f456nolpxb9"> <div class="fl-row-content-wrap"> <div class="fl-row-content fl-row-fixed-width fl-node-content"> <div class="fl-col-group fl-node-z6qdni3vbhe1" data-node="z6qdni3vbhe1"> <div class="fl-col fl-node-vnyzimw457ro fl-col-bg-color" data-node="vnyzimw457ro"> <div class="fl-col-content fl-node-content"><div class="fl-module fl-module-ee-page-title fl-node-pwtvgy2bhd09" data-node="pwtvgy2bhd09"> <div class="fl-module-content fl-node-content">  <div class="ee-page-title"> <h1> Pre-Conference Workshop Day 2024 </h1> </div> </div> </div> <div class="fl-module fl-module-ee-agenda fl-node-vzln7xt6gim3" data-node="vzln7xt6gim3"> <div class="fl-module-content fl-node-content"> <div class="content"> <div class="inner-agenda" style="background: "> <h3> <span class="time"> 7:30 am </span> <center><span style="color: #67A5CB;">Check-in & Light Breakfast</span></center> </h3>   <div class="clearfix"></div>  <div class="agenda-content"> </div>  </div> <div class="inner-agenda" style="background: #f0f0f0"> <h3> <span class="time"> </span> </h3> <style id='fl-builder-layout-24158-inline-css'> .fl-node-mh5q69udbyj3 {width: 50%;}.fl-node-pya7oqbi3nfx {width: 50%;}.inner-agenda {background: #f0f0f0;margin-bottom: 20px;padding: 20px;}.inner-agenda:last-child {margin-bottom: 0px;}.inner-agenda span.time {color: #28367d ;}.inner-agenda h3 {color: #000;font-size: 16px;}h3.eehw-agenda-synopsis {color: #28367d ;padding-top: 20px;}h1.eehw-agenda-title {background: #28367d ;color: #fff;font-weight: bold;margin-bottom: 20px;margin-top: 0px;padding: 20px;}h1.eehw-agenda-title p {margin: 0;font-size: 18px;font-weight: bold;margin-top: 5px;}.fl-module-ee-agenda ul.non-expand-speaker-list {padding-left: 0px;}.fl-module-ee-agenda ul.non-expand-speaker-list li {list-style: none;text-indent: 0px;}.eehw-speaker {margin-top: 30px;}.eehw-speakers-thumb {float: left;margin-right: 20px;}.inner-agenda-workshop p ul li {list-style-type: square;margin: 10px 0px;text-indent: 3px;width: 100%;}.inner-agenda-workshop h2 {font-size: 22px;}a.view-speaker {display: block;}.fl-module-ee-agenda .fl-builder-layout-template .fl-row-content-wrap {margin: 0;padding: 0;background: #f0f0f0;margin-bottom: 20px;}@media screen and (max-width: 768px) {}.inner-agenda {background: #f0f0f0;margin-bottom: 20px;padding: 20px;}.inner-agenda:last-child {margin-bottom: 0px;}.inner-agenda span.time {color: #28367d ;}.inner-agenda h3 {color: #000;font-size: 16px;}h3.eehw-agenda-synopsis {color: #28367d ;padding-top: 20px;}h1.eehw-agenda-title {background: #28367d ;color: #fff;font-weight: bold;margin-bottom: 20px;margin-top: 0px;padding: 20px;}h1.eehw-agenda-title p {margin: 0;font-size: 18px;font-weight: bold;margin-top: 5px;}.fl-module-ee-agenda ul.non-expand-speaker-list {padding-left: 0px;}.fl-module-ee-agenda ul.non-expand-speaker-list li {list-style: none;text-indent: 0px;}.eehw-speaker {margin-top: 30px;}.eehw-speakers-thumb {float: left;margin-right: 20px;}.inner-agenda-workshop p ul li {list-style-type: square;margin: 10px 0px;text-indent: 3px;width: 100%;}.inner-agenda-workshop h2 {font-size: 22px;}a.view-speaker {display: block;}.fl-module-ee-agenda .fl-builder-layout-template .fl-row-content-wrap {margin: 0;padding: 0;background: #f0f0f0;margin-bottom: 20px;}@media screen and (max-width: 768px) {} </style> <div class="fl-builder-content fl-builder-content-24158 fl-builder-template fl-builder-layout-template fl-builder-global-templates-locked" data-post-id="24158"><div class="fl-row fl-row-fixed-width fl-row-bg-none fl-node-j5uc6bl8gw4r fl-row-default-height fl-row-align-center" data-node="j5uc6bl8gw4r"> <div class="fl-row-content-wrap"> <div class="fl-row-content fl-row-fixed-width fl-node-content"> <div class="fl-col-group fl-node-cre5480jkugm" data-node="cre5480jkugm"> <div class="fl-col fl-node-mh5q69udbyj3 fl-col-bg-color fl-col-small" data-node="mh5q69udbyj3"> <div class="fl-col-content fl-node-content"><div class="fl-module fl-module-ee-agenda fl-node-e1ulp24ftdnm" data-node="e1ulp24ftdnm"> <div class="fl-module-content fl-node-content"> <div class="content"> <div class="inner-agenda" style="background: #3b0b71"> <h3> <span class="time"> </span> <center><span style="color: #FFFFFF;"> Workshop A</span></center> </h3>   <div class="clearfix"></div>  <div class="agenda-content"> </div>  </div> <div class="inner-agenda" style="background: #deecf4"> <h3> <span class="time"> 8:30 am </span> Meeting Your Match: Examining Physical Properties of Isotopes to Understand Their Effect Across Varying Disease Characteristics </h3>  <ul class="non-expand-speaker-list"> <li> <em><a href="https://targeted-radiopharma.com/speakers/#speaker24461" class="view-speaker" speaker-id="24461"><span>Julien Torgue</span></a></em> Chief Scientific Officer, OranoMed </li> <li> <em><a href="https://targeted-radiopharma.com/speakers/#speaker24471" class="view-speaker" speaker-id="24471"><span>Justine perrin</span></a></em> Post doctoral researcher, Erasmus MC Cancer Institute </li> <li> <em><a href="https://targeted-radiopharma.com/speakers/#speaker24554" class="view-speaker" speaker-id="24554"><span>Gregory Mullen</span></a></em> Chief Executive Officer, Ariceum Therapeutics </li> </ul>  <div class="clearfix"></div>  <div class="agenda-content"> <h3 class="eehw-agenda-synopsis"> Synopsis </h3> <p>Selecting the appropriate isotope for targeted radiotherapy involves a thorough understanding of both the properties of the isotopes and the specific characteristics of the disease being treated. This requires an integration of knowledge from nuclear physics, oncology, and immunohistopathology.</p> <p></p> <p>In this workshop, we will delve into considerations for isotope selection to bring optimal treatment outcomes:</p> <ul> <li>Matching isotope properties with disease properties by examining radiation type and energy from alpha, beta, and gamma emitters</li> <li>Exploring effects of isotope half-life and decay pathways, from short-lived to long-lived isotopes</li> <li>Assessing the optimal blend of biological half-life, physical half-life and targeting moiety</li> <li>Navigating criteria to be considered for isotope selection such as tumour type and location and</li> <li>microenvironmental features</li> <li>Outlining targeting mechanisms delivering the isotope to the tumour and considerations for optimal isotope selection</li> <li>Understanding immune profiles stimulated – activation and recruitment of immune cells at the tumor site after radionuclide therapy, and impact of the treatment on tumor immune resistance</li> </ul> </div>  </div> </div> </div> </div> </div> </div> <div class="fl-col fl-node-pya7oqbi3nfx fl-col-bg-color fl-col-small" data-node="pya7oqbi3nfx"> <div class="fl-col-content fl-node-content"><div class="fl-module fl-module-ee-agenda fl-node-3mzbtvq5feo1" data-node="3mzbtvq5feo1"> <div class="fl-module-content fl-node-content"> <div class="content"> <div class="inner-agenda" style="background: #ef0063"> <h3> <span class="time"> </span> <center><span style="color: #FFFFFF;"> Workshop D</span></center> </h3>   <div class="clearfix"></div>  <div class="agenda-content"> </div>  </div> <div class="inner-agenda" style="background: #efbfd3"> <h3> <span class="time"> 8:30 am </span> Implementing Targeted Radiopharmaceuticals into More Hospitals to Expand Access From Clinic to Approval </h3>  <ul class="non-expand-speaker-list"> <li> <em><a href="https://targeted-radiopharma.com/speakers/#speaker23972" class="view-speaker" speaker-id="23972"><span>Jasminka Taleska</span></a></em> Global Director RLT HCS Readiness & RLT Policy Strategy, Novartis AG </li> <li> <em><a href="https://targeted-radiopharma.com/speakers/#speaker23973" class="view-speaker" speaker-id="23973"><span>Vineet Prakash</span></a></em> Consultant in Nuclear Medicine and Radiology, Royal Surrey County Hospital </li> <li> <em><a href="https://targeted-radiopharma.com/speakers/#speaker23970" class="view-speaker" speaker-id="23970"><span>Leonhard Schaetz</span></a></em> Head Health Systems Partnership RLT international, Novartis AG </li> <li> <em><a href="https://targeted-radiopharma.com/speakers/#speaker24272" class="view-speaker" speaker-id="24272"><span>Luke Brzozowski</span></a></em> Executive Director, Theranostics and Core Facilities, University Health Network </li> </ul>  <div class="clearfix"></div>  <div class="agenda-content"> <h3 class="eehw-agenda-synopsis"> Synopsis </h3> <p>Integrating targeted radiopharmaceuticals into hospitals involves ensuring healthcare readiness, adapting hospital infrastructure for nuclear medicine, addressing the specific requirements for handling alpha emitters, and developing strategies to increase the availability and use of radiopharmaceuticals in healthcare settings.</p> <p></p> <p>Expert teams will uncover:</p> <ul> <li>What it means to have healthcare readiness from clinical integration with interdisciplinary teams and clinical protocols, training, and readiness</li> <li>Exploring how to effectively adapt hospitals for nuclear medicine by looking at the infrastructure requirements, dedicated facilities, and radiation safety measures</li> <li>Understanding the scope around compassionate use programs</li> <li>Engaging with policymakers and regulatory bodies to advocate for supportive policies and regulations that facilitate the adoption and use of radiopharmaceuticals in clinical practice</li> </ul> </div>  </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div class="inner-agenda" style="background: "> <h3> <span class="time"> 10:30 am </span> <center><span style="color: #67A5CB;">Morning Break & Networking</span></center> </h3>   <div class="clearfix"></div>  <div class="agenda-content"> </div>  </div> <div class="inner-agenda" style="background: #f0f0f0"> <h3> <span class="time"> </span> </h3> <style id='fl-builder-layout-24161-inline-css'> .fl-node-8hst6r5eu9xl {width: 50%;}.fl-node-0c6vez54upys {width: 50%;}.inner-agenda {background: #f0f0f0;margin-bottom: 20px;padding: 20px;}.inner-agenda:last-child {margin-bottom: 0px;}.inner-agenda span.time {color: #28367d ;}.inner-agenda h3 {color: #000;font-size: 16px;}h3.eehw-agenda-synopsis {color: #28367d ;padding-top: 20px;}h1.eehw-agenda-title {background: #28367d ;color: #fff;font-weight: bold;margin-bottom: 20px;margin-top: 0px;padding: 20px;}h1.eehw-agenda-title p {margin: 0;font-size: 18px;font-weight: bold;margin-top: 5px;}.fl-module-ee-agenda ul.non-expand-speaker-list {padding-left: 0px;}.fl-module-ee-agenda ul.non-expand-speaker-list li {list-style: none;text-indent: 0px;}.eehw-speaker {margin-top: 30px;}.eehw-speakers-thumb {float: left;margin-right: 20px;}.inner-agenda-workshop p ul li {list-style-type: square;margin: 10px 0px;text-indent: 3px;width: 100%;}.inner-agenda-workshop h2 {font-size: 22px;}a.view-speaker {display: block;}.fl-module-ee-agenda .fl-builder-layout-template .fl-row-content-wrap {margin: 0;padding: 0;background: #f0f0f0;margin-bottom: 20px;}@media screen and (max-width: 768px) {}.inner-agenda {background: #f0f0f0;margin-bottom: 20px;padding: 20px;}.inner-agenda:last-child {margin-bottom: 0px;}.inner-agenda span.time {color: #28367d ;}.inner-agenda h3 {color: #000;font-size: 16px;}h3.eehw-agenda-synopsis {color: #28367d ;padding-top: 20px;}h1.eehw-agenda-title {background: #28367d ;color: #fff;font-weight: bold;margin-bottom: 20px;margin-top: 0px;padding: 20px;}h1.eehw-agenda-title p {margin: 0;font-size: 18px;font-weight: bold;margin-top: 5px;}.fl-module-ee-agenda ul.non-expand-speaker-list {padding-left: 0px;}.fl-module-ee-agenda ul.non-expand-speaker-list li {list-style: none;text-indent: 0px;}.eehw-speaker {margin-top: 30px;}.eehw-speakers-thumb {float: left;margin-right: 20px;}.inner-agenda-workshop p ul li {list-style-type: square;margin: 10px 0px;text-indent: 3px;width: 100%;}.inner-agenda-workshop h2 {font-size: 22px;}a.view-speaker {display: block;}.fl-module-ee-agenda .fl-builder-layout-template .fl-row-content-wrap {margin: 0;padding: 0;background: #f0f0f0;margin-bottom: 20px;}@media screen and (max-width: 768px) {} </style> <div class="fl-builder-content fl-builder-content-24161 fl-builder-template fl-builder-layout-template fl-builder-global-templates-locked" data-post-id="24161"><div class="fl-row fl-row-fixed-width fl-row-bg-none fl-node-bc4wgquzeltd fl-row-default-height fl-row-align-center" data-node="bc4wgquzeltd"> <div class="fl-row-content-wrap"> <div class="fl-row-content fl-row-fixed-width fl-node-content"> <div class="fl-col-group fl-node-3qx4m2d8wuct" data-node="3qx4m2d8wuct"> <div class="fl-col fl-node-8hst6r5eu9xl fl-col-bg-color fl-col-small" data-node="8hst6r5eu9xl"> <div class="fl-col-content fl-node-content"><div class="fl-module fl-module-ee-agenda fl-node-ahutn17wercd" data-node="ahutn17wercd"> <div class="fl-module-content fl-node-content"> <div class="content"> <div class="inner-agenda" style="background: #3b0b71"> <h3> <span class="time"> </span> <center><span style="color: #FFFFFF;"> Workshop B</span></center> </h3>   <div class="clearfix"></div>  <div class="agenda-content"> </div>  </div> <div class="inner-agenda" style="background: #deecf4"> <h3> <span class="time"> 11:00 am </span> Expanding Radiopharmaceutical Targeting Mechanisms with Novel Moieties to Harness Enhanced Specificity, Efficacy & Safety </h3>  <ul class="non-expand-speaker-list"> <li> <em><a href="https://targeted-radiopharma.com/speakers/#speaker24274" class="view-speaker" speaker-id="24274"><span>Jeremy Paull</span></a></em> VP Development and Regulatory Affairs, Starpharma Ltd. </li> <li> <em><a href="https://targeted-radiopharma.com/speakers/#speaker23975" class="view-speaker" speaker-id="23975"><span>Michel Afargan</span></a></em> CTO, Starget Pharma </li> <li> <em><a href="https://targeted-radiopharma.com/speakers/#speaker24579" class="view-speaker" speaker-id="24579"><span>Daniel Steiner</span></a></em> Senior Vice President Research & Technology, Molecular Partners AG </li> </ul>  <div class="clearfix"></div>  <div class="agenda-content"> <h3 class="eehw-agenda-synopsis"> Synopsis </h3> <p>The development of novel targeting moieties for radiopharmaceuticals has seen significant advancements, particularly in the context of targeting cancer cells and supporting tissues. These novel moieties include small peptides, cyclic peptides, bispecifics and nanobodies, each offering unique advantages in terms of specificity, stability, and pharmacokinetics.</p> <p></p> <p>Uncovering the latest understandings and developments across novel targeting approaches, this</p> <p>workshop will:</p> <ul> <li>Reveal more novel small peptides for enhanced specificity, affinity and rapid clearance</li> <li>Explore cyclic peptides for degradation resistance, improved binding and extended circulation time</li> <li>Interrogate nanobodies for better tissue penetration and rapid clearance and high stability</li> <li>Maximisebispecific antibodies for synergistic effects</li> <li>Examine existing targeting mechanisms such as antibodies and antibody fragments to assess their viability as isotope conjugates</li> <li>What should you be looking for to understand what makes a good targeting moiety</li> </ul> <p></p> </div>  </div> </div> </div> </div> </div> </div> <div class="fl-col fl-node-0c6vez54upys fl-col-bg-color fl-col-small" data-node="0c6vez54upys"> <div class="fl-col-content fl-node-content"><div class="fl-module fl-module-ee-agenda fl-node-rg63ksatm1q9" data-node="rg63ksatm1q9"> <div class="fl-module-content fl-node-content"> <div class="content"> <div class="inner-agenda" style="background: #ef0063"> <h3> <span class="time"> </span> <center><span style="color: #FFFFFF;"> Workshop E</span></center> </h3>   <div class="clearfix"></div>  <div class="agenda-content"> </div>  </div> <div class="inner-agenda" style="background: #efbfd3"> <h3> <span class="time"> 11:00 am </span> Enhancing Excellence & Execution While Working with Different Radiopharmaceutical Supply Chain & Manufacturing Players </h3>  <ul class="non-expand-speaker-list"> <li> <em><a href="https://targeted-radiopharma.com/speakers/#speaker23964" class="view-speaker" speaker-id="23964"><span>Neydher Berroteran-Infante</span></a></em> Director - Chemistry, Manufacturing & Controls,Discovery Science, PentixaPharm GmbH </li> <li> <em><a href="https://targeted-radiopharma.com/speakers/#speaker23780" class="view-speaker" speaker-id="23780"><span>Daniel Rossetto</span></a></em> Senior Vice President & Head Of Supply Chain & External Manufacturing, ARTBIO </li> <li> <em><a href="https://targeted-radiopharma.com/speakers/#speaker23781" class="view-speaker" speaker-id="23781"><span>Vimal Patel</span></a></em> Vice President - Chemistry Manufacturing & Controls, RadioPharm Theranostics </li> </ul>  <div class="clearfix"></div>  <div class="agenda-content"> <h3 class="eehw-agenda-synopsis"> Synopsis </h3> <p>Developing and delivering radiopharmaceuticals requires seamless coordination with various supply chain and manufacturing players. This involves ensuring that all parties have the right capabilities and expertise to maintain quality, safety, and efficiency throughout the process. Both in-house teams and external players must work together efficiently to delivery high-quality radiopharmaceuticals.</p> <p></p> <p>This workshop will provide key learnings, case-studies and expert insights addressing:</p> <p></p> <ul> <li>Building a team of highly trained and quality supply chain and manufacturing personnel</li> <li>Exploring best practices for CDMO selection and management</li> <li>Drilling into technical expertise and learnings to drive strong technology transfer and regulatory navigation</li> <li>Developing strong communications with partners to drive streamlined information-sharing</li> </ul> </div>  </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div class="inner-agenda" style="background: "> <h3> <span class="time"> 1:00 pm </span> <center><span style="color: #67A5CB;"> Lunch Break & Networking</span></center> </h3>   <div class="clearfix"></div>  <div class="agenda-content"> </div>  </div> <div class="inner-agenda" style="background: #f0f0f0"> <h3> <span class="time"> </span> </h3> <style id='fl-builder-layout-24164-inline-css'> .fl-node-e4b2u5a3nhpk {width: 50%;}.fl-node-5j6vry182u9s {width: 50%;}.inner-agenda {background: #f0f0f0;margin-bottom: 20px;padding: 20px;}.inner-agenda:last-child {margin-bottom: 0px;}.inner-agenda span.time {color: #28367d ;}.inner-agenda h3 {color: #000;font-size: 16px;}h3.eehw-agenda-synopsis {color: #28367d ;padding-top: 20px;}h1.eehw-agenda-title {background: #28367d ;color: #fff;font-weight: bold;margin-bottom: 20px;margin-top: 0px;padding: 20px;}h1.eehw-agenda-title p {margin: 0;font-size: 18px;font-weight: bold;margin-top: 5px;}.fl-module-ee-agenda ul.non-expand-speaker-list {padding-left: 0px;}.fl-module-ee-agenda ul.non-expand-speaker-list li {list-style: none;text-indent: 0px;}.eehw-speaker {margin-top: 30px;}.eehw-speakers-thumb {float: left;margin-right: 20px;}.inner-agenda-workshop p ul li {list-style-type: square;margin: 10px 0px;text-indent: 3px;width: 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{list-style-type: square;margin: 10px 0px;text-indent: 3px;width: 100%;}.inner-agenda-workshop h2 {font-size: 22px;}a.view-speaker {display: block;}.fl-module-ee-agenda .fl-builder-layout-template .fl-row-content-wrap {margin: 0;padding: 0;background: #f0f0f0;margin-bottom: 20px;}@media screen and (max-width: 768px) {} </style> <div class="fl-builder-content fl-builder-content-24164 fl-builder-template fl-builder-layout-template fl-builder-global-templates-locked" data-post-id="24164"><div class="fl-row fl-row-fixed-width fl-row-bg-none fl-node-ge7ildxw956p fl-row-default-height fl-row-align-center" data-node="ge7ildxw956p"> <div class="fl-row-content-wrap"> <div class="fl-row-content fl-row-fixed-width fl-node-content"> <div class="fl-col-group fl-node-uehv6p4g7wqc" data-node="uehv6p4g7wqc"> <div class="fl-col fl-node-e4b2u5a3nhpk fl-col-bg-color fl-col-small" data-node="e4b2u5a3nhpk"> <div class="fl-col-content fl-node-content"><div class="fl-module fl-module-ee-agenda fl-node-4zfydkoi53th" data-node="4zfydkoi53th"> <div class="fl-module-content fl-node-content"> <div class="content"> <div class="inner-agenda" style="background: #3b0b71"> <h3> <span class="time"> 1:45 pm </span> <center><span style="color: #FFFFFF;"> Workshop C</span></center> </h3>   <div class="clearfix"></div>  <div class="agenda-content"> </div>  </div> <div class="inner-agenda" style="background: #deecf4"> <h3> <span class="time"> 2:00 pm </span> Designing Optimal First in Human Radiopharmaceutical Trials for Translational Success: Regulatory Considerations </h3>  <ul class="non-expand-speaker-list"> <li> <em><a href="https://targeted-radiopharma.com/speakers/#speaker23766" class="view-speaker" speaker-id="23766"><span>Ming Xu</span></a></em> Vice President, Product Team Leader (PTL) for RED Oncology, Bayer </li> <li> <em><a href="https://targeted-radiopharma.com/speakers/#speaker24638" class="view-speaker" speaker-id="24638"><span>Ben Pais</span></a></em> CMO, Nuclidium </li> </ul>  <div class="clearfix"></div>  <div class="agenda-content"> <h3 class="eehw-agenda-synopsis"> Synopsis </h3> <p>First-in-human radiopharmaceutical trials are critical for assessing the safety, pharmacokinetics, dosimetry, and preliminary efficacy of new radiopharmaceuticals. The design of these trials must be meticulous to ensure patient safety while gathering essential data. Key components include patient monitoring duration, dose toxicity assessment, and primary readouts. </p> <p></p> <p>Join this workshop to:</p> <ul> <li>Uncover pre, during and post-treatment monitoring</li> <li>Determine your dose escalation and safety reviews</li> <li>Exploring dosimetry from absorbed dose calculation and dose response relationships</li> <li>Dealing with waste disposal, radiation safety and logistical challenges with alpha emitters</li> <li>Considerations for Project Optimus</li> </ul> </div>  </div> </div> </div> </div> </div> </div> <div class="fl-col fl-node-5j6vry182u9s fl-col-bg-color fl-col-small" data-node="5j6vry182u9s"> <div class="fl-col-content fl-node-content"><div class="fl-module fl-module-ee-agenda fl-node-16beoy9vramh" data-node="16beoy9vramh"> <div class="fl-module-content fl-node-content"> <div class="content"> <div class="inner-agenda" style="background: #ef0063"> <h3> <span class="time"> </span> <center><span style="color: #FFFFFF;"> Workshop F</span></center> </h3>   <div class="clearfix"></div>  <div class="agenda-content"> </div>  </div> <div class="inner-agenda" style="background: #efbfd3"> <h3> <span class="time"> 2:00 pm </span> Ensuring Radiopharmaceutical Quality: Mechanistic Understandings, Safety & Measuring & Sustaining Drug Product Quality </h3>  <ul class="non-expand-speaker-list"> <li> <em><a href="https://targeted-radiopharma.com/speakers/#speaker24148" class="view-speaker" speaker-id="24148"><span>Laurent Durous</span></a></em> Scientist, Bayer </li> <li> <em><a href="https://targeted-radiopharma.com/speakers/#speaker24473" class="view-speaker" speaker-id="24473"><span>Isaac Simmonds</span></a></em> Associate Director - Radiochemistry, Rayzebio </li> </ul>  <div class="clearfix"></div>  <div class="agenda-content"> <h3 class="eehw-agenda-synopsis"> Synopsis </h3> <p>Limitations in measuring alpha emitters directly <span style="font-size: 13px;">requires a focus on maintaining</span> quality control in the clinics following global shipment. Crucial to the success and safety of your drug is the analytical testing to ensure a quality product <span style="font-size: 13px;">is administered to patients.</span> Beyond maintaining drug quality, investigations are ongoing to understand what happens following radiopharmaceuticals accumulating in the target and subsequent decay pathways.</p> <p></p> <p>Experts will dive into discussions on:</p> <ul> <li>Understanding how to measure drug product quality when unable to measure alpha daughters</li> <li>Rapid identity testing of antibody-based hot targeted radionuclide therapies by bio-layer interferometry</li> <li>Maintaining traceability</li> <li>Exploring what innovations could help measure quality</li> <li>Investigating potential systemic toxicity effects</li> </ul> </div>  </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div class="inner-agenda" style="background: "> <h3> <span class="time"> 4:00 pm </span> <center><span style="color: 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field=$(this),val=field.val(),placeholder=field.attr('placeholder');if('undefined'!=placeholder&&''===val){field.val(placeholder);field.on('focus',FLBuilderLayout._hideFormFieldPlaceholderFallback);field.on('blur',FLBuilderLayout._showFormFieldPlaceholderFallback);}},_hideFormFieldPlaceholderFallback:function(){var field=$(this),val=field.val(),placeholder=field.attr('placeholder');if(val==placeholder){field.val('');}},_showFormFieldPlaceholderFallback:function(){var field=$(this),val=field.val(),placeholder=field.attr('placeholder');if(''===val){field.val(placeholder);}},_clearFormFieldError:function(){var field=$(this);field.removeClass('fl-form-error');field.siblings('.fl-form-error-message').hide();},_initRowShapeLayerHeight:function(){FLBuilderLayout._adjustRowShapeLayerHeight();$(window).on('resize',FLBuilderLayout._adjustRowShapeLayerHeight);},_initNestedColsWidth:function(){var nestedCols=$('.fl-col-has-cols');if(nestedCols.length<=0){return;} $(nestedCols).each(function(index,col){if($(col).width()<=0){$(col).css('width',FLBuilderLayoutConfig.emptyColWidth);}});},_adjustRowShapeLayerHeight:function(){var rowShapeLayers=$('.fl-builder-shape-layer');$(rowShapeLayers).each(function(index){var rowShapeLayer=$(this),shape=$(rowShapeLayer).find('svg'),height=shape.height(),excludeShapes='.fl-builder-shape-circle, .fl-builder-shape-dot-cluster, .fl-builder-shape-topography, .fl-builder-shape-rect';if(!rowShapeLayer.is(excludeShapes)){$(shape).css('height',Math.ceil(height));}});},_string_to_slug:function(str){str=str.replace(/^\s+|\s+$/g,'');if('undefined'==typeof window._fl_string_to_slug_regex){regex=new RegExp('[^a-zA-Z0-9\'":() !.,-_|]','g');}else{regex=new RegExp('[^'+window._fl_string_to_slug_regex+'\'": !.,-_|\\\p{Letter}]','ug');} str=str.replace(regex,'').replace(/\s+/g,' ');return str;},_reorderMenu:function(){if($('#wp-admin-bar-fl-builder-frontend-edit-link-default li').length>1){$('#wp-admin-bar-fl-builder-frontend-duplicate-link').appendTo('#wp-admin-bar-fl-builder-frontend-edit-link-default').css('padding-top','5px').css('border-top','2px solid #1D2125').css('margin-top','5px')}}};$(function(){FLBuilderLayout.init();});})(jQuery);;;;jQuery(function($){$(function(){$('.fl-node-gmcr61obln0x .fl-photo-img').on('mouseenter',function(e){$(this).data('title',$(this).attr('title')).removeAttr('title');}).on('mouseleave',function(e){$(this).attr('title',$(this).data('title')).data('title',null);});});window._fl_string_to_slug_regex='a-zA-Z0-9';});;(function($){$(function(){$('.fl-map').on('click',function(){$(this).find('iframe').css('pointer-events','auto');});});})(jQuery);;jQuery(function($){$(function(){$('.fl-node-oq6c3pengd7t .fl-photo-img').on('mouseenter',function(e){$(this).data('title',$(this).attr('title')).removeAttr('title');}).on('mouseleave',function(e){$(this).attr('title',$(this).data('title')).data('title',null);});});window._fl_string_to_slug_regex='a-zA-Z0-9';});;(function($){FLBuilderMenu=function(settings){this.nodeId=settings.id;this.nodeClass='.fl-node-'+settings.id;this.wrapperClass=this.nodeClass+' .fl-menu';this.type=settings.type;this.mobileToggle=settings.mobile;this.mobileBelowRow=settings.mobileBelowRow;this.mobileFlyout=settings.mobileFlyout;this.breakPoints=settings.breakPoints;this.mobileBreakpoint=settings.mobileBreakpoint;this.currentBrowserWidth=$(window).width();this.postId=settings.postId;this.mobileStacked=settings.mobileStacked;this._initMenu();$(window).on('resize',$.proxy(function(e){var width=$(window).width();if(width!=this.currentBrowserWidth){this.currentBrowserWidth=width;this._initMenu();this._clickOrHover();} this._resizeFlyoutMenuPanel();},this));$(window).on('scroll',$.proxy(function(e){this._resizeFlyoutMenuPanel();},this));$('body').on('click',$.proxy(function(e){if('undefined'!==typeof FLBuilderConfig){return;} var activeMobileMenu=$(this.wrapperClass+' .fl-menu-mobile-toggle.fl-active');if(activeMobileMenu.length&&('expanded'!==this.mobileToggle)){$(activeMobileMenu).trigger('click');} $(this.wrapperClass).find('.fl-has-submenu').removeClass('focus');$(this.wrapperClass).find('.fl-has-submenu .sub-menu').removeClass('focus');},this));$(this.wrapperClass+' ul.menu > li:last-child').on('focusout',$.proxy(function(e){if($(this.wrapperClass).find('.fl-menu-mobile-toggle').hasClass('fl-active')&&('expanded'!==this.mobileToggle)){if(!$(e.relatedTarget).parent().hasClass('menu-item')){$(this.wrapperClass).find('.fl-menu-mobile-toggle').trigger('click');}}},this));};FLBuilderMenu.prototype={nodeClass:'',wrapperClass:'',type:'',breakPoints:{},$submenus:null,_isMobile:function(){return this.currentBrowserWidth<=this.breakPoints.small?true:false;},_isMedium:function(){return this.currentBrowserWidth<=this.breakPoints.medium?true:false;},_isLarge:function(){return this.currentBrowserWidth<=this.breakPoints.large?true:false;},_isMenuToggle:function(){if(('always'==this.mobileBreakpoint||(this._isMobile()&&'mobile'==this.mobileBreakpoint)||(this._isMedium()&&'medium-mobile'==this.mobileBreakpoint)||(this._isLarge()&&'large-mobile'==this.mobileBreakpoint))&&($(this.wrapperClass).find('.fl-menu-mobile-toggle').is(':visible')||'expanded'==this.mobileToggle)){return true;} return false;},_initMenu:function(){this._setupSubmenu();this._menuOnFocus();this._menuOnEscape();this._submenuOnClick();if($(this.nodeClass).length&&this.type=='horizontal'){this._initMegaMenus();} if(this._isMenuToggle()||this.type=='accordion'){$(this.wrapperClass).off('mouseenter mouseleave');this._menuOnClick();this._clickOrHover();}else{$(this.wrapperClass).off('click');this._submenuOnRight();this._submenuRowZindexFix();} if(this.mobileToggle!='expanded'){this._toggleForMobile();} if($(this.wrapperClass).find('.fl-menu-search-item').length){this._toggleMenuSearch();} if($(this.wrapperClass).find('.fl-menu-cart-item').length){this._wooUpdateParams();}},_setupSubmenu:function(){$(this.wrapperClass+' ul.sub-menu').each(function(){$(this).closest('li').attr('aria-haspopup','true');});},_menuOnFocus:function(){var cKey=0,isShifted=false;$(this.nodeClass).off('keydown').on('keydown','a',function(e){cKey=e.which;isShifted=e.shiftKey;});$(this.nodeClass).off('focus').on('focus','a',$.proxy(function(e){var $menuItem=$(e.target).parents('.menu-item').first(),$parents=$(e.target).parentsUntil(this.wrapperClass);$('.fl-menu .focus').removeClass('focus');$parents.addClass('focus') if(!$menuItem.closest('.fl-has-submenu').hasClass('escaped')){$menuItem.addClass('focus')} else{$menuItem.closest('.fl-has-submenu').removeClass('focus escaped')}},this)).on('focusout','a',$.proxy(function(e){var el=$(e.target).parent(),$megaMenu=el.closest('.mega-menu'),$megaLastItem=$megaMenu.find('> .sub-menu > .menu-item:last-child'),$lastItem=el.parents('.fl-has-submenu:last').find('.menu-item:last'),isLastChild=!$megaMenu.length&&el.is($lastItem);if($megaMenu.length){isLastChild=el.is($megaLastItem)||el.is($megaLastItem.find('.menu-item:last-child'));} if(isLastChild&&cKey===9&&isShifted){isLastChild=false;cKey=0;isShifted=false;} else if(cKey===27){isLastChild=false;} if(isLastChild){$(e.target).parentsUntil(this.wrapperClass).removeClass('focus');}},this));},_menuOnEscape:function(){$('body').off('keydown').on('keydown',$.proxy(function(e){if(e.which!==27){return;} if($(e.target).closest('.menu-item').length){var activeSubmenu=null,menuItem=$(e.target).closest('.menu-item'),type=menuItem.closest('.fl-menu-accordion').length?'accordion':'horizontal';if('horizontal'===type){if(menuItem.hasClass('fl-has-submenu')&&menuItem.hasClass('focus')){activeSubmenu=menuItem.find('> ul.sub-menu');} else{activeSubmenu=menuItem.closest('ul.sub-menu');} activeSubmenu.parent().addClass('escaped');activeSubmenu.parent().find('a:first').focus();} else{if(menuItem.hasClass('fl-has-submenu')&&'accordion'===type&&menuItem.hasClass('fl-active')){activeSubmenu=menuItem.find('> ul.sub-menu');} else{activeSubmenu=menuItem.closest('ul.sub-menu');} activeSubmenu.slideUp(400,function(){if(menuItem.hasClass('fl-has-submenu')&&menuItem.hasClass('fl-active')){activeSubmenu.parent().last().find('a:first').focus();} else{menuItem.removeClass('focus');menuItem.parents('.menu-item').first().find('a:first').focus();} activeSubmenu.parent().last().removeClass('fl-active');});}} else{$('.fl-menu').find('li.menu-item.focus').last().removeClass('focus');}},this));},_menuOnClick:function(){$(this.wrapperClass).off().on('click','.fl-has-submenu-container',$.proxy(function(e){var $link=$(e.target).parents('.fl-has-submenu').first(),$subMenu=$link.children('.sub-menu').first(),$href=$link.children('.fl-has-submenu-container').first().find('> a').attr('href'),$subMenuParents=$(e.target).parents('.sub-menu'),$activeParents=$(e.target).parents('.fl-has-submenu.fl-active');if(!$subMenu.is(':visible')||$(e.target).hasClass('fl-menu-toggle')||($subMenu.is(':visible')&&(typeof $href==='undefined'||$href=='#'))){e.preventDefault();} else{e.stopPropagation();window.location.href=$href;return;} if($(this.wrapperClass).hasClass('fl-menu-accordion-collapse')){if(!$link.parents('.menu-item').hasClass('fl-active')){$('.menu .fl-active',this.wrapperClass).not($link).removeClass('fl-active');} else if($link.parents('.menu-item').hasClass('fl-active')&&$link.parent('.sub-menu').length){$('.menu .fl-active',this.wrapperClass).not($link).not($activeParents).removeClass('fl-active');} $('.sub-menu',this.wrapperClass).not($subMenu).not($subMenuParents).slideUp('normal');} if(!this.mobileStacked&&'horizontal'==this.type&&'expanded'==this.mobileToggle){$(this.wrapperClass).find('.fl-active').not($link).not($activeParents).removeClass('fl-active');} else{$subMenu.slideToggle();} $link.toggleClass('fl-active');e.stopPropagation();},this));},_submenuOnClick:function(){$(this.wrapperClass+' .sub-menu').off().on('click','a',$.proxy(function(e){if($(e.target).parent().hasClass('focus')){$(e.target).parentsUntil(this.wrapperClass).removeClass('focus');}},this));},_clickOrHover:function(){this.$submenus=this.$submenus||$(this.wrapperClass).find('.sub-menu');var $wrapper=$(this.wrapperClass),$menu=$wrapper.find('.menu');$li=$wrapper.find('.fl-has-submenu');if(this._isMenuToggle()){$li.each(function(el){if(!$(this).hasClass('fl-active')){$(this).find('.sub-menu').fadeOut();}});}else{$li.each(function(el){if(!$(this).hasClass('fl-active')){$(this).find('.sub-menu').css({'display':'','opacity':''});}});}},_submenuOnRight:function(){$(this.wrapperClass).on('mouseenter focus','.fl-has-submenu',$.proxy(function(e){if($(e.currentTarget).find('.sub-menu').length===0){return;} var $link=$(e.currentTarget),$parent=$link.parent(),$subMenu=$link.find('.sub-menu'),subMenuWidth=$subMenu.width(),subMenuPos=0,bodyWidth=$('body').width();if($link.closest('.fl-menu-submenu-right').length!==0){$link.addClass('fl-menu-submenu-right');}else if($('body').hasClass('rtl')){subMenuPos=$parent.is('.sub-menu')?$parent.offset().left-subMenuWidth:$link.offset().left-$link.width()-subMenuWidth;if(subMenuPos<=0){$link.addClass('fl-menu-submenu-right');}}else{subMenuPos=$parent.is('.sub-menu')?$parent.offset().left+$parent.width()+subMenuWidth:$link.offset().left+$link.width()+subMenuWidth;if(subMenuPos>bodyWidth){$link.addClass('fl-menu-submenu-right');}}},this)).on('mouseleave','.fl-has-submenu',$.proxy(function(e){$(e.currentTarget).removeClass('fl-menu-submenu-right');},this));},_submenuRowZindexFix:function(e){$(this.wrapperClass).on('mouseenter','ul.menu > .fl-has-submenu',$.proxy(function(e){if($(e.currentTarget).find('.sub-menu').length===0){return;} $(this.nodeClass).closest('.fl-row').find('.fl-row-content').css('z-index','10');},this)).on('mouseleave','ul.menu > .fl-has-submenu',$.proxy(function(e){$(this.nodeClass).closest('.fl-row').find('.fl-row-content').css('z-index','');},this));},_toggleForMobile:function(){var $wrapper=null,$menu=null,self=this;if(this._isMenuToggle()){if(this._isMobileBelowRowEnabled()){this._placeMobileMenuBelowRow();$wrapper=$(this.wrapperClass);$menu=$(this.nodeClass+'-clone');$menu.find('ul.menu').show();} else{$wrapper=$(this.wrapperClass);$menu=$wrapper.find('.menu');} if(!$wrapper.find('.fl-menu-mobile-toggle').hasClass('fl-active')&&!self.mobileFlyout){$menu.css({display:'none'});} if(self.mobileFlyout){this._initFlyoutMenu();} $wrapper.on('click','.fl-menu-mobile-toggle',function(e){$(this).toggleClass('fl-active');if(self.mobileFlyout){self._toggleFlyoutMenu();} else{var targetMenu=null;if(self.mobileBelowRow){targetMenu=$(this).closest('.fl-col').next('.fl-menu-mobile-clone');}else{targetMenu=$(this).closest('.fl-menu').find('ul.menu');} if(targetMenu.length){$menu=$(targetMenu);} $menu.slideToggle();} e.stopPropagation();});$menu.off().on('click','.menu-item > a[href*="#"]:not([href="#"])',function(e){var $href=$(this).attr('href'),$targetID=$href.split('#')[1],element=$('#'+$targetID);if($('body').find(element).length>0){$(this).toggleClass('fl-active');FLBuilderLayout._scrollToElement(element);if(!self._isMenuToggle()){$menu.slideToggle();}}});} else{if(this._isMobileBelowRowEnabled()){this._removeMenuFromBelowRow();} $wrapper=$(this.wrapperClass),$menu=$wrapper.find('ul.menu');$wrapper.find('.fl-menu-mobile-toggle').removeClass('fl-active');$menu.css({display:''});if(!this._isMobileBelowRowEnabled()){$menu.off('click','.menu-item > a[href*="#"]:not([href="#"])');} if(this.mobileFlyout&&$wrapper.find('.fl-menu-mobile-flyout').length>0){$('body').css('margin','');$('.fl-builder-ui-pinned-content-transform').css('transform','');$menu.unwrap();$wrapper.find('.fl-menu-mobile-close').remove();$wrapper.find('.fl-menu-mobile-opacity').remove();}}},_initMegaMenus:function(){var module=$(this.nodeClass),rowContent=module.closest('.fl-row-content'),rowWidth=rowContent.width(),megas=module.find('.mega-menu'),disabled=module.find('.mega-menu-disabled'),isToggle=this._isMenuToggle();if(isToggle){megas.removeClass('mega-menu').addClass('mega-menu-disabled');module.find('li.mega-menu-disabled > ul.sub-menu').css('width','');rowContent.css('position','');}else{disabled.removeClass('mega-menu-disabled').addClass('mega-menu');module.find('li.mega-menu > ul.sub-menu').css('width',rowWidth+'px');rowContent.css('position','relative');}},_isMobileBelowRowEnabled:function(){return this.mobileBelowRow&&$(this.nodeClass).closest('.fl-col').length;},_placeMobileMenuBelowRow:function(){if($(this.nodeClass+'-clone').length){return;} var module=$(this.nodeClass),clone=null,col=module.closest('.fl-col');if(module.length<1){return;} clone=(module.length>1)?$(module[0]).clone():module.clone();module.find('ul.menu').remove();clone.addClass((this.nodeClass+'-clone').replace('.',''));clone.addClass('fl-menu-mobile-clone');clone.find('.fl-menu-mobile-toggle').remove();col.after(clone);if(module.hasClass('fl-animation')){clone.removeClass('fl-animation');} this._menuOnClick();},_removeMenuFromBelowRow:function(){if(!$(this.nodeClass+'-clone').length){return;} var module=$(this.nodeClass),clone=$(this.nodeClass+'-clone'),menu=clone.find('ul.menu');module.find('.fl-menu-mobile-toggle').after(menu);clone.remove();menu.find('a').each(FLBuilderLayout._initAnchorLink);},_initFlyoutMenu:function(){var win=$(window),wrapper=$(this.wrapperClass),menu=wrapper.find('ul.menu'),button=wrapper.find('.fl-menu-mobile-toggle');if(0===wrapper.find('.fl-menu-mobile-flyout').length){menu.wrap('<div class="fl-menu-mobile-flyout"></div>');} if(0===wrapper.find('.fl-menu-mobile-close').length){close=window.fl_responsive_close||'Close' wrapper.find('.fl-menu-mobile-flyout').prepend('<button class="fl-menu-mobile-close" aria-label="'+close+'"><i class="fas fa-times" aria-hidden="true"></i></button>');} if(wrapper.hasClass('fl-menu-responsive-flyout-push-opacity')&&0===wrapper.find('.fl-menu-mobile-opacity').length){wrapper.append('<div class="fl-menu-mobile-opacity"></div>');} wrapper.on('click','.fl-menu-mobile-opacity, .fl-menu-mobile-close',function(e){button.trigger('click');e.stopPropagation();});if('undefined'!==typeof FLBuilder){FLBuilder.addHook('restartEditingSession',function(){$('.fl-builder-ui-pinned-content-transform').css('transform','');if(button.hasClass('fl-active')){button.trigger('click');}});}},_toggleFlyoutMenu:function(){var wrapper=$(this.wrapperClass),button=wrapper.find('.fl-menu-mobile-toggle'),wrapFlyout=wrapper.find('.fl-menu-mobile-flyout'),position=wrapper.hasClass('fl-flyout-right')?'right':'left',pushMenu=wrapper.hasClass('fl-menu-responsive-flyout-push')||wrapper.hasClass('fl-menu-responsive-flyout-push-opacity'),opacity=wrapper.find('.fl-menu-mobile-opacity'),marginPos={},posAttr={},fixedPos={},winHeight=$(window).height(),fixedHeader=$('header, header > div');this._resizeFlyoutMenuPanel();if($('.fl-builder-ui-pinned-content-transform').length>0&&!$('body').hasClass('fl-builder-edit')){$('.fl-builder-ui-pinned-content-transform').css('transform','none');} if(pushMenu){marginPos['margin-'+position]=button.hasClass('fl-active')?'250px':'0px';$('body').animate(marginPos,200);if(fixedHeader.length>0){fixedPos[position]=button.hasClass('fl-active')?'250px':'0px';fixedHeader.each(function(){if('fixed'==$(this).css('position')){$(this).css({'-webkit-transition':'none','-o-transition':'none','transition':'none'});$(this).animate(fixedPos,200);}});}} if(opacity.length>0&&button.hasClass('fl-active')){opacity.show();} else{opacity.hide();}},_resizeFlyoutMenuPanel:function(){const wrapper=$(this.wrapperClass);const wrapFlyout=wrapper.find('.fl-menu-mobile-flyout');if(wrapFlyout.length>0){wrapFlyout.css(this._getFlyoutMenuPanelPosition());}},_getFlyoutMenuPanelPosition:function(){var wrapper=$(this.wrapperClass),button=wrapper.find('.fl-menu-mobile-toggle'),wrapFlyout=wrapper.find('.fl-menu-mobile-flyout'),side=wrapper.hasClass('fl-flyout-right')?'right':'left',winHeight=$(window).outerHeight(),winTop=$(window).scrollTop(),adminBarHeight=$('#wpadminbar').length?$('#wpadminbar').height():0,flyoutPosition={};flyoutPosition[side]='-267px';if(!button.hasClass('fl-active')){return flyoutPosition;} flyoutPosition[side]='0px';flyoutPosition['height']=winHeight+'px';flyoutPosition['top']='0px';if(adminBarHeight>0){const diff=adminBarHeight-winTop;flyoutPosition['top']=diff<=0?'0px':(diff)+'px';} return flyoutPosition;},_toggleMenuSearch:function(){var wrapper=$(this.wrapperClass).find('.fl-menu-search-item'),button=wrapper.find('a.fl-button'),form=wrapper.find('.fl-search-form-input-wrap'),self=this;button.on('click',function(e){e.preventDefault();if(form.is(':visible')){form.stop().fadeOut(200);} else{form.stop().fadeIn(200);$('body').on('click.fl-menu-search',$.proxy(self._hideMenuSearch,self));form.find('.fl-search-text').focus();}});},_hideMenuSearch:function(e){var form=$(this.wrapperClass).find('.fl-search-form-input-wrap');if(e!==undefined){if($(e.target).closest('.fl-menu-search-item').length>0){return;}} form.stop().fadeOut(200);$('body').off('click.fl-menu-search');},_wooUpdateParams:function(){if('undefined'!==typeof wc_cart_fragments_params){wc_cart_fragments_params.wc_ajax_url+='&fl-menu-node='+this.nodeId+'&post-id='+this.postId;} if('undefined'!==typeof wc_add_to_cart_params){wc_add_to_cart_params.wc_ajax_url+='&fl-menu-node='+this.nodeId+'&post-id='+this.postId;}},};})(jQuery);;(function($){$(function(){new FLBuilderMenu({id:'5ba1fe150af69',type:'horizontal',mobile:'text',mobileBelowRow:true,mobileFlyout:false,breakPoints:{large:1200,medium:992,small:768},mobileBreakpoint:'medium-mobile',postId:'54',mobileStacked:true,});});})(jQuery);;jQuery(function($){$(function(){$('.fl-node-5c5c3f70d801a .fl-photo-img').on('mouseenter',function(e){$(this).data('title',$(this).attr('title')).removeAttr('title');}).on('mouseleave',function(e){$(this).attr('title',$(this).data('title')).data('title',null);});});window._fl_string_to_slug_regex='a-zA-Z0-9';});;(function($){FLThemeBuilderHeaderLayout={win:null,body:null,header:null,overlay:false,hasAdminBar:false,stickyOn:'',breakpointWidth:0,init:function(){var editing=$('html.fl-builder-edit').length,header=$('.fl-builder-content[data-type=header]'),menuModule=header.find('.fl-module-menu'),breakpoint=null;if(!editing&&header.length){header.imagesLoaded($.proxy(function(){this.win=$(window);this.body=$('body');this.header=header.eq(0);this.overlay=!!Number(header.attr('data-overlay'));this.hasAdminBar=!!$('body.admin-bar').length;this.stickyOn=this.header.data('sticky-on');breakpoint=this.header.data('sticky-breakpoint');if(''==this.stickyOn){if(typeof FLBuilderLayoutConfig.breakpoints[breakpoint]!==undefined){this.breakpointWidth=FLBuilderLayoutConfig.breakpoints[breakpoint];} else{this.breakpointWidth=FLBuilderLayoutConfig.breakpoints.medium;}} if(Number(header.attr('data-sticky'))){this.header.data('original-top',this.header.offset().top);this.win.on('resize',$.throttle(500,$.proxy(this._initSticky,this)));this._initSticky();}},this));}},_initSticky:function(e){var header=$('.fl-builder-content[data-type=header]'),windowSize=this.win.width(),makeSticky=false;makeSticky=this._makeWindowSticky(windowSize);if(makeSticky||(this.breakpointWidth>0&&windowSize>=this.breakpointWidth)){this.win.on('scroll.fl-theme-builder-header-sticky',$.proxy(this._doSticky,this));if(e&&'resize'===e.type){if(this.header.hasClass('fl-theme-builder-header-sticky')){this._doSticky(e);} this._adjustStickyHeaderWidth();} if(Number(header.attr('data-shrink'))){this.header.data('original-height',this.header.outerHeight());this.win.on('resize',$.throttle(500,$.proxy(this._initShrink,this)));this._initShrink();} this._initFlyoutMenuFix(e);}else{this.win.off('scroll.fl-theme-builder-header-sticky');this.win.off('resize.fl-theme-builder-header-sticky');this.header.removeClass('fl-theme-builder-header-sticky');this.header.removeAttr('style');this.header.parent().css('padding-top','0');}},_makeWindowSticky:function(windowSize){var makeSticky=false;switch(this.stickyOn){case'xl':makeSticky=windowSize>FLBuilderLayoutConfig.breakpoints['large'];break;case'':case'desktop':makeSticky=windowSize>=FLBuilderLayoutConfig.breakpoints['medium'];break;case'desktop-medium':makeSticky=windowSize>FLBuilderLayoutConfig.breakpoints['small'];break;case'large':makeSticky=windowSize>FLBuilderLayoutConfig.breakpoints['medium']&&windowSize<=FLBuilderLayoutConfig.breakpoints['large'];break;case'large-medium':makeSticky=windowSize>FLBuilderLayoutConfig.breakpoints['small']&&windowSize<=FLBuilderLayoutConfig.breakpoints['large'];break;case'medium':makeSticky=(windowSize<=FLBuilderLayoutConfig.breakpoints['medium']&&windowSize>FLBuilderLayoutConfig.breakpoints['small']);break;case'medium-mobile':makeSticky=(windowSize<=FLBuilderLayoutConfig.breakpoints['medium']);break;case'mobile':makeSticky=(windowSize<=FLBuilderLayoutConfig.breakpoints['small']);break;case'all':makeSticky=true;break;} return makeSticky;},_doSticky:function(e){var winTop=Math.floor(this.win.scrollTop()),headerTop=Math.floor(this.header.data('original-top')),hasStickyClass=this.header.hasClass('fl-theme-builder-header-sticky'),hasScrolledClass=this.header.hasClass('fl-theme-builder-header-scrolled'),beforeHeader=this.header.prevAll('.fl-builder-content'),bodyTopPadding=parseInt(jQuery('body').css('padding-top')),winBarHeight=$('#wpadminbar').length?$('#wpadminbar').outerHeight():0,headerHeight=0;if(isNaN(bodyTopPadding)){bodyTopPadding=0;} if(this.hasAdminBar&&this.win.width()>600){winTop+=Math.floor(winBarHeight);} if(winTop>headerTop){if(!hasStickyClass){if(e&&('scroll'===e.type||'smartscroll'===e.type)){this.header.addClass('fl-theme-builder-header-sticky');if(this.overlay&&beforeHeader.length){this.header.css('top',winBarHeight);}} if(!this.overlay){this._adjustHeaderHeight();}}} else if(hasStickyClass){this.header.removeClass('fl-theme-builder-header-sticky');this.header.removeAttr('style');this.header.parent().css('padding-top','0');} this._adjustStickyHeaderWidth();if(winTop>headerTop){if(!hasScrolledClass){this.header.addClass('fl-theme-builder-header-scrolled');}}else if(hasScrolledClass){this.header.removeClass('fl-theme-builder-header-scrolled');} this._flyoutMenuFix(e);},_initFlyoutMenuFix:function(e){var header=this.header,menuModule=header.closest('.fl-menu'),flyoutMenu=menuModule.find('.fl-menu-mobile-flyout'),isPushMenu=menuModule.hasClass('fl-menu-responsive-flyout-push')||menuModule.hasClass('fl-menu-responsive-flyout-push-opacity'),isOverlay=menuModule.hasClass('fl-menu-responsive-flyout-overlay'),flyoutPos=menuModule.hasClass('fl-flyout-right')?'right':'left',flyoutParent=header.parent().is('header')?header.parent().parent():header.parent();isFullWidth=this.win.width()===header.width(),flyoutLayout='',activePos=250,headerPos=0;if(!flyoutMenu.length){return;} if(this.win.width()>header.parent().width()){headerPos=(this.win.width()-header.width())/ 2;} if(isOverlay){activePos=headerPos;} else if(isPushMenu){activePos=activePos+headerPos;} flyoutMenu.data('activePos',activePos);if(isPushMenu){flyoutLayout='push-'+flyoutPos;} else if(isOverlay){flyoutLayout='overlay-'+flyoutPos;} if(isPushMenu&&!$('html').hasClass('fl-theme-builder-has-flyout-menu')){$('html').addClass('fl-theme-builder-has-flyout-menu');} if(!flyoutParent.hasClass('fl-theme-builder-flyout-menu-'+flyoutLayout)){flyoutParent.addClass('fl-theme-builder-flyout-menu-'+flyoutLayout);} if(!header.hasClass('fl-theme-builder-flyout-menu-overlay')&&isOverlay){header.addClass('fl-theme-builder-flyout-menu-overlay');} if(!header.hasClass('fl-theme-builder-header-full-width')&&isFullWidth){header.addClass('fl-theme-builder-header-full-width');} else if(!isFullWidth){header.removeClass('fl-theme-builder-header-full-width');} menuModule.on('click','.fl-menu-mobile-toggle',$.proxy(function(event){if(menuModule.find('.fl-menu-mobile-toggle.fl-active').length){$('html').addClass('fl-theme-builder-flyout-menu-active');event.stopImmediatePropagation();} else{$('html').removeClass('fl-theme-builder-flyout-menu-active');} this._flyoutMenuFix(event);},this));},_flyoutMenuFix:function(e){var header=this.header,menuModule=$(e.target).closest('.fl-menu'),flyoutMenu=menuModule.find('.fl-menu-mobile-flyout'),flyoutPos=menuModule.hasClass('fl-flyout-right')?'right':'left',menuOpacity=menuModule.find('.fl-menu-mobile-opacity'),isScroll='undefined'!==typeof e&&'scroll'===e.handleObj.type,activePos='undefined'!==typeof flyoutMenu.data('activePos')?flyoutMenu.data('activePos'):0,headerPos=(this.win.width()-header.width())/ 2,inactivePos=headerPos>0?activePos+4:254;if(!flyoutMenu.length){return;} if(this.overlay){return;} if($('.fl-theme-builder-flyout-menu-active').length){if(isScroll&&!flyoutMenu.hasClass('fl-menu-disable-transition')){flyoutMenu.addClass('fl-menu-disable-transition');} if(header.hasClass('fl-theme-builder-header-sticky')){if(!isScroll){setTimeout($.proxy(function(){flyoutMenu.css(flyoutPos,'-'+activePos+'px');},this),1);} else{flyoutMenu.css(flyoutPos,'-'+activePos+'px');}} else{flyoutMenu.css(flyoutPos,'0px');}} else{if(flyoutMenu.hasClass('fl-menu-disable-transition')){flyoutMenu.removeClass('fl-menu-disable-transition');} if(header.hasClass('fl-theme-builder-flyout-menu-overlay')&&headerPos>0&&headerPos<250){if(header.hasClass('fl-theme-builder-header-sticky')){inactivePos=headerPos+254;} else{inactivePos=254;}} if(e&&e.type==='resize'){inactivePos=headerPos+254;} flyoutMenu.css(flyoutPos,'-'+inactivePos+'px');} if(e&&menuModule.is('.fl-menu-responsive-flyout-overlay')&&$.infinitescroll){e.stopImmediatePropagation();} if(menuOpacity.length){if(header.hasClass('fl-theme-builder-header-sticky')){if('0px'===menuOpacity.css('left')){menuOpacity.css('left','-'+headerPos+'px');}} else{menuOpacity.css('left','');}}},_adjustStickyHeaderWidth:function(){if($('body').hasClass('fl-fixed-width')){var parentWidth=this.header.parent().width();if(this.win.width()>=992){this.header.css({'margin':'0 auto','max-width':parentWidth,});} else{this.header.css({'margin':'','max-width':'',});}}},_adjustHeaderHeight:function(){var beforeHeader=this.header.prevAll('.fl-builder-content'),beforeHeaderHeight=0,beforeHeaderFix=0,headerHeight=Math.floor(this.header.outerHeight()),bodyTopPadding=parseInt($('body').css('padding-top')),wpAdminBarHeight=0,totalHeaderHeight=0;if(isNaN(bodyTopPadding)){bodyTopPadding=0;} if(beforeHeader.length){$.each(beforeHeader,function(){beforeHeaderHeight+=Math.floor($(this).outerHeight());});beforeHeaderFix=2;} if(this.hasAdminBar&&this.win.width()<=600){wpAdminBarHeight=Math.floor($('#wpadminbar').outerHeight());} totalHeaderHeight=Math.floor(beforeHeaderHeight+headerHeight);if(headerHeight>0){var headerParent=this.header.parent(),headerParentTopPadding=0;if($(headerParent).is('body')){headerParentTopPadding=Math.floor(headerHeight-wpAdminBarHeight);}else{headerParentTopPadding=Math.floor(headerHeight-bodyTopPadding-wpAdminBarHeight);} $(headerParent).css('padding-top',(headerParentTopPadding-beforeHeaderFix)+'px');this.header.css({'-webkit-transform':'translate(0px, -'+totalHeaderHeight+'px)','-ms-transform':'translate(0px, -'+totalHeaderHeight+'px)','transform':'translate(0px, -'+totalHeaderHeight+'px)'});}},_initShrink:function(e){if(this.win.width()>=this.breakpointWidth){this.win.on('scroll.fl-theme-builder-header-shrink',$.proxy(this._doShrink,this));this._setImageMaxHeight();if(this.win.scrollTop()>0){this._doShrink();}}else{this.header.parent().css('padding-top','0');this.win.off('scroll.fl-theme-builder-header-shrink');this._removeShrink();this._removeImageMaxHeight();}},_doShrink:function(e){var winTop=this.win.scrollTop(),headerTop=this.header.data('original-top'),headerHeight=this.header.data('original-height'),shrinkImageHeight=this.header.data('shrink-image-height'),windowSize=this.win.width(),makeSticky=this._makeWindowSticky(windowSize),hasClass=this.header.hasClass('fl-theme-builder-header-shrink');if(this.hasAdminBar){winTop+=32;} if(makeSticky&&(winTop>headerTop+headerHeight)){if(!hasClass){this.header.addClass('fl-theme-builder-header-shrink');this.header.find('img').each(function(i){var image=$(this),maxMegaMenu=image.closest('.max-mega-menu').length,imageInLightbox=image.closest('.fl-button-lightbox-content').length,imageInNavMenu=image.closest('li.menu-item').length;if(!(imageInLightbox||imageInNavMenu||maxMegaMenu)){image.css('max-height',shrinkImageHeight);}});this.header.find('.fl-row-content-wrap').each(function(){var row=$(this);if(parseInt(row.css('padding-bottom'))>5){row.addClass('fl-theme-builder-header-shrink-row-bottom');} if(parseInt(row.css('padding-top'))>5){row.addClass('fl-theme-builder-header-shrink-row-top');}});this.header.find('.fl-module-content').each(function(){var module=$(this);if(parseInt(module.css('margin-bottom'))>5){module.addClass('fl-theme-builder-header-shrink-module-bottom');} if(parseInt(module.css('margin-top'))>5){module.addClass('fl-theme-builder-header-shrink-module-top');}});}}else if(hasClass){this.header.find('img').css('max-height','');this._removeShrink();} if('undefined'===typeof(e)&&$('body').hasClass('fl-fixed-width')){if(!this.overlay){this._adjustHeaderHeight();}}},_removeShrink:function(){var rows=this.header.find('.fl-row-content-wrap'),modules=this.header.find('.fl-module-content');rows.removeClass('fl-theme-builder-header-shrink-row-bottom');rows.removeClass('fl-theme-builder-header-shrink-row-top');modules.removeClass('fl-theme-builder-header-shrink-module-bottom');modules.removeClass('fl-theme-builder-header-shrink-module-top');this.header.removeClass('fl-theme-builder-header-shrink');},_setImageMaxHeight:function(){var head=$('head'),stylesId='fl-header-styles-'+this.header.data('post-id'),styles='',images=this.header.find('.fl-module-content img');if($('#'+stylesId).length){return;} images.each(function(i){var image=$(this),height=image.height(),node=image.closest('.fl-module').data('node'),className='fl-node-'+node+'-img-'+i,maxMegaMenu=image.closest('.max-mega-menu').length,imageInLightbox=image.closest('.fl-button-lightbox-content').length,imageInNavMenu=image.closest('li.menu-item').length;if(!(imageInLightbox||imageInNavMenu||maxMegaMenu)){image.addClass(className);styles+='.'+className+' { max-height: '+(height?height:image[0].height)+'px }';}});if(''!==styles){head.append('<style id="'+stylesId+'">'+styles+'</style>');}},_removeImageMaxHeight:function(){$('#fl-header-styles-'+this.header.data('post-id')).remove();},};$(function(){FLThemeBuilderHeaderLayout.init();});})(jQuery);</script><script type="text/javascript" src="https://onsite.optimonk.com/script.js?account=197068" async></script></body> </html>