CINXE.COM
Assay Development | VENENUM Biodesign
<!doctype html> <html lang="en"> <head> <meta charset="utf-8"> <meta name="viewport" content="width=device-width"> <title>Assay Development | VENENUM Biodesign</title> <meta name="Description" content="VENENUM Biodesign."> <link rel="apple-touch-icon" sizes="180x180" href="https://www.venenumbiodesign.com/images/favicons/apple-touch-icon.png"> <link rel="icon" type="image/png" sizes="32x32" href="https://www.venenumbiodesign.com/images/favicons/favicon-32x32.png"> <link rel="icon" type="image/png" sizes="16x16" href="https://www.venenumbiodesign.com/images/favicons/favicon-16x16.png"> <link rel="manifest" href="https://www.venenumbiodesign.com/images/favicons/site.webmanifest"> <link rel="mask-icon" href="https://www.venenumbiodesign.com/images/favicons/safari-pinned-tab.svg" color=""> <meta name="msapplication-TileColor" content="#"> <meta name="theme-color" content=""> <link rel="stylesheet" href="https://www.venenumbiodesign.com/css/style.css?v=1720118701"> <link rel="stylesheet" href="https://www.venenumbiodesign.com/css/interior.css?v=1708118066"> <link rel="stylesheet" href="https://www.venenumbiodesign.com/css/bootstrap.css?v=1688416623"> <link rel="stylesheet" href="https://fonts.googleapis.com/css?family=Ubuntu:400,400italic,500,700,700italic,500italic"> <script>var $site = "https://www.venenumbiodesign.com", $page = "assays", $template = "interior", $mods = "https://www.genesisglobalgrp.com/mods/";</script> <script type="module">var body=document.querySelector("body");function show(b,c,a){document.querySelector(b).classList.toggle(c),null!==a&&a()}function lazyLoadImages(){for(var b=document.querySelectorAll(".preload"),c=new IntersectionObserver(function(d){for(var b=0;b<d.length;b++)if(!0===d[b].isIntersecting){var a=d[b].target,e=a.getAttribute("data-src"),f=a.getAttribute("data-srcset");null!==e&&(a.src=e),null!==f&&(a.srcset=f),a.classList.add("loaded"),c.unobserve(a)}}),a=0;a<b.length;a++)c.observe(b[a])}window.addEventListener("load",function(){body.classList.add("loaded"),window.show=show}),document.addEventListener("DOMContentLoaded",lazyLoadImages,!1);var inView=new IntersectionObserver(function(a){for(i=0;i<a.length;i++)!0===a[i].isIntersecting&&a[i].target.parentNode.classList.add("in-view")},{threshold:[1]});setTimeout(function(){Array.prototype.forEach.call(document.querySelectorAll(".viewBox"),function(a,b){inView.observe(a)})},500)</script> <script src="https://www.venenumbiodesign.com/js/jquery.min.js?v=1688416629" ></script> <!-- Global site tag (gtag.js) - Google Analytics --> <script async src="https://www.googletagmanager.com/gtag/js?id="></script> <script> window.dataLayer = window.dataLayer || []; function gtag(){dataLayer.push(arguments);} gtag("js", new Date()); gtag("config", ""); </script> </head> <body class="page-assays temp-interior spring" style="--mainColor: #367CB9; --subColor: #254467;"> <div id="wrapper"> <header class="header clearfix"> <a href="https://www.venenumbiodesign.com"> <h1 class="Ven-logo"><img src="https://www.genesisglobalgrp.com/mods/images/logo_venenum.png" alt="" height="83"></h1> </a> <ul class="nav_menu nav"> <li class=""> <a href="https://www.venenumbiodesign.com/" class="nav_link"> <strong>Home</strong> </a> <li class=" parent active-parent"> <a href="https://www.venenumbiodesign.com/about/" class="nav_link"> <strong>About Us</strong> </a> <ul class="submenu"> <li class=""> <a href="https://www.venenumbiodesign.com/about/corporate/" class="sub_nav_link"> <strong>Corporate</strong> </a> <li class=""> <a href="https://www.venenumbiodesign.com/about/leadership/" class="sub_nav_link"> <strong>Scientific Leadership</strong> </a> <li class="active-page "> <a href="https://www.venenumbiodesign.com/about/assays/" class="sub_nav_link"> <strong>Assay Development</strong> </a> <li class=""> <a href="https://www.venenumbiodesign.com/about/compounds/" class="sub_nav_link"> <strong>Compound Collection</strong> </a> <li class=""> <a href="https://www.venenumbiodesign.com/about/lead/" class="sub_nav_link"> <strong>Hit-to-Lead & Lead Optimization</strong> </a> <li class=""> <a href="https://www.venenumbiodesign.com/about/biology/" class="sub_nav_link"> <strong>Structural Biology</strong> </a> </li> </ul> <li class=""> <a href="https://www.venenumbiodesign.com/pipeline/" class="nav_link"> <strong>Pipeline</strong> </a> <li class=" parent"> <a href="https://www.venenumbiodesign.com/links/news/" class="nav_link"> <strong>Links</strong> </a> <ul class="submenu"> <li class=""> <a href="https://www.venenumbiodesign.com/links/news/" class="sub_nav_link"> <strong>News and Events</strong> </a> <li class=""> <a href="https://www.venenumbiodesign.com/links/publications/" class="sub_nav_link"> <strong>Publications</strong> </a> <li class=""> <a href="https://us232.dayforcehcm.com/CandidatePortal/en-US/ggg/SITE/VenenumCareerSite" class="sub_nav_link"> <strong>Careers</strong> </a> <li class=""> <a href="https://www.venenumbiodesign.com/links/partnerships/" class="sub_nav_link"> <strong>Partnerships</strong> </a> </li> </ul> <li class=""> <a href="https://www.venenumbiodesign.com/contact/" class="nav_link"> <strong>Contact Us</strong> </a> </li> </ul> <a class="logo-gd3" href="https://www.gd3services.com"> <img id = "gd" src="https://www.genesisglobalgrp.com/mods/images/logo_gd3.png" width="100"> </a> <a class="logo-ggg" href="https://www.genesisglobalgrp.com/" target="_blank"> <img src="https://www.genesisglobalgrp.com/mods/images/logo_ggg_member.png" alt="A Member of Genesis Global Group" width="265"> </a> </header> <section class="content clearfix"> <div class="page-contain clearfix"> <div class="page-side-nav"> <ul class="side_nav"> <li class=""> <a href="https://www.venenumbiodesign.com/about-us/corporate/" class="nav_link"> <strong>Corporate</strong> </a> </li> <li class=""> <a href="https://www.venenumbiodesign.com/about-us/leadership/" class="nav_link"> <strong>Scientific Leadership</strong> </a> </li> <li class="active-page "> <a href="https://www.venenumbiodesign.com/about-us/assays/" class="nav_link"> <strong>Assay Development</strong> </a> </li> <li class=""> <a href="https://www.venenumbiodesign.com/about-us/compounds/" class="nav_link"> <strong>Compound Collection</strong> </a> </li> <li class=""> <a href="https://www.venenumbiodesign.com/about-us/lead/" class="nav_link"> <strong>Hit-to-Lead & Lead Optimization</strong> </a> </li> <li class=""> <a href="https://www.venenumbiodesign.com/about-us/biology/" class="nav_link"> <strong>Structural Biology</strong> </a> </li> </ul> <div> <h1>Careers Page</h1><hr> <p>Please view our career page for future employment with Venenum Biodesign.</p> <p><a href="https://us232.dayforcehcm.com/CandidatePortal/en-US/ggg/SITE/VenenumCareerSite" target="_blank">View Job Postings</a></p> </div> </div> <div class="page-content"> <h1>Assay Development</h1> <hr> <p style="">For UHTS, we develop in vitro biological assays that are suitable for screening our 5.5 million ECLiPS compound collection in 1536-well format. This includes both cell-based and biochemical assays designed to measure ligand binding, enzymatic activity, and cell function. Ideal UHTS detection technologies include, but are not limited to, fluorescence, fluorescence resonance energy transfer (FRET), time-resolved fluorescence (TRF), homogeneous time-resolved fluorescence (HTRF or TR-TRET), absorbance, luminescence, and AlphaScreen庐. Screening assays can be configured with either kinetic or endpoint detection.</p> <p style="">Our biology team also develops assays for compound profiling at the hit-to-lead and lead optimization stage. These assays, typically in low-volume 384-well format, allow for the implementation of a fully-integrated critical path that extends beyond primary compound testing to include selectivity and ortholog profiling.</p> <p style=""><span style="font-weight: normal;">V<span style="font-size: 10px;">ENENUM</span> <span style="text-transform: none;"><em><strong>Bio</strong>design</em></span></span> utilizes state-of-the-art liquid handling and detection technology, allowing optimization of assays with high reproducibility and sensitivity. We establish CVs, z-factors, and work with reference compounds to ensure assay quality. We employ a combination of custom microliter liquid handlers along with commercial instruments such as the JANUS, Multidrop Combi, and ATS-100 acoustic dispenser. Our detection instrumentation includes Envisions, ViewLux, and FLiPR-Tetra multimode plate readers.</p> </div> </div> </section> <footer class="footer clearfix"> <div> <ul> <li><a href="https://www.venenumbiodesign.com/" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-home current-menu-item page_item page-item-5 current_page_item">Home</a></li> <li><a href="https://www.venenumbiodesign.com/contact/" class="menu-item menu-item-type-post_type menu-item-object-page">Contact Us</a></li> <li><a target="_blank" href="https://www.genesisbiotechgroup.com/legal/" class="menu-item menu-item-type-custom menu-item-object-custom">Terms of Use</a></li> <li><a target="_blank" href="https://www.genesisbiotechgroup.com/legal/#privacy" class="menu-item menu-item-type-custom menu-item-object-custom">Privacy Policy</a></li> </ul> <div class="social-media"> <a target="_blank" class="twitter" href="https://twitter.com/GenesisBioJobs">twitter</a> <a target="_blank" class="linkedin" href="http://www.linkedin.com/company/2853321?trk=vsrp_companies_res_name&trkInfo=VSRPsearchId%3A1417214151375805658045%2CVSRPtargetId%3A2853321%2CVSRPcmpt%3Aprimary">linkedin</a> </div> </div> <p> Copyright ©2024 VENENUM Biodesign<br />All Rights Reserved. </p> </footer> </div> </body> </html>