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Disponible en 34 idiomas" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-34" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">34 idiomas</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-ar mw-list-item"><a href="https://ar.wikipedia.org/wiki/%D8%B3%D8%A7%D8%B1%D9%83%D9%88%D9%85%D8%A7_%D8%B9%D8%B8%D9%85%D9%8A%D8%A9" title="ساركوما عظمية (árabe)" lang="ar" hreflang="ar" data-title="ساركوما عظمية" data-language-autonym="العربية" data-language-local-name="árabe" class="interlanguage-link-target"><span>العربية</span></a></li><li class="interlanguage-link interwiki-bg mw-list-item"><a href="https://bg.wikipedia.org/wiki/%D0%9E%D1%81%D1%82%D0%B5%D0%BE%D1%81%D0%B0%D1%80%D0%BA%D0%BE%D0%BC" title="Остеосарком (búlgaro)" lang="bg" hreflang="bg" data-title="Остеосарком" data-language-autonym="Български" data-language-local-name="búlgaro" class="interlanguage-link-target"><span>Български</span></a></li><li class="interlanguage-link interwiki-bs mw-list-item"><a href="https://bs.wikipedia.org/wiki/Osteosarkom" title="Osteosarkom (bosnio)" lang="bs" hreflang="bs" data-title="Osteosarkom" data-language-autonym="Bosanski" data-language-local-name="bosnio" class="interlanguage-link-target"><span>Bosanski</span></a></li><li class="interlanguage-link interwiki-ca mw-list-item"><a href="https://ca.wikipedia.org/wiki/Osteosarcoma" title="Osteosarcoma (catalán)" lang="ca" hreflang="ca" data-title="Osteosarcoma" data-language-autonym="Català" data-language-local-name="catalán" class="interlanguage-link-target"><span>Català</span></a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/Osteosarkom" title="Osteosarkom (alemán)" lang="de" hreflang="de" data-title="Osteosarkom" data-language-autonym="Deutsch" data-language-local-name="alemán" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-dv mw-list-item"><a href="https://dv.wikipedia.org/wiki/%DE%87%DE%AE%DE%90%DE%B0%DE%93%DE%A8%DE%87%DE%AF%DE%96%DE%AC%DE%82%DE%A8%DE%86%DE%B0_%DE%90%DE%A7%DE%83%DE%86%DE%AF%DE%89%DE%A7" title="އޮސްޓިއޯޖެނިކް ސާރކޯމާ (divehi)" lang="dv" hreflang="dv" data-title="އޮސްޓިއޯޖެނިކް ސާރކޯމާ" data-language-autonym="ދިވެހިބަސް" data-language-local-name="divehi" class="interlanguage-link-target"><span>ދިވެހިބަސް</span></a></li><li class="interlanguage-link interwiki-en mw-list-item"><a href="https://en.wikipedia.org/wiki/Osteosarcoma" title="Osteosarcoma (inglés)" lang="en" hreflang="en" data-title="Osteosarcoma" data-language-autonym="English" data-language-local-name="inglés" class="interlanguage-link-target"><span>English</span></a></li><li class="interlanguage-link interwiki-eo mw-list-item"><a href="https://eo.wikipedia.org/wiki/Ostosarkomo" title="Ostosarkomo (esperanto)" lang="eo" hreflang="eo" data-title="Ostosarkomo" data-language-autonym="Esperanto" data-language-local-name="esperanto" class="interlanguage-link-target"><span>Esperanto</span></a></li><li class="interlanguage-link interwiki-eu mw-list-item"><a href="https://eu.wikipedia.org/wiki/Osteosarkoma" title="Osteosarkoma (euskera)" lang="eu" hreflang="eu" data-title="Osteosarkoma" data-language-autonym="Euskara" data-language-local-name="euskera" class="interlanguage-link-target"><span>Euskara</span></a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/%D8%A7%D8%B3%D8%AA%D8%A6%D9%88%D8%B3%D8%A7%D8%B1%DA%A9%D9%88%D9%85" title="استئوسارکوم (persa)" lang="fa" hreflang="fa" data-title="استئوسارکوم" data-language-autonym="فارسی" data-language-local-name="persa" class="interlanguage-link-target"><span>فارسی</span></a></li><li class="interlanguage-link interwiki-fi mw-list-item"><a href="https://fi.wikipedia.org/wiki/Osteosarkooma" title="Osteosarkooma (finés)" lang="fi" hreflang="fi" data-title="Osteosarkooma" data-language-autonym="Suomi" data-language-local-name="finés" class="interlanguage-link-target"><span>Suomi</span></a></li><li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/Ost%C3%A9osarcome" title="Ostéosarcome (francés)" lang="fr" hreflang="fr" data-title="Ostéosarcome" data-language-autonym="Français" data-language-local-name="francés" class="interlanguage-link-target"><span>Français</span></a></li><li class="interlanguage-link interwiki-ha mw-list-item"><a href="https://ha.wikipedia.org/wiki/Osteosarcoma" title="Osteosarcoma (hausa)" lang="ha" hreflang="ha" data-title="Osteosarcoma" data-language-autonym="Hausa" data-language-local-name="hausa" class="interlanguage-link-target"><span>Hausa</span></a></li><li class="interlanguage-link interwiki-hr mw-list-item"><a href="https://hr.wikipedia.org/wiki/Osteosarkom" title="Osteosarkom (croata)" lang="hr" hreflang="hr" data-title="Osteosarkom" data-language-autonym="Hrvatski" data-language-local-name="croata" class="interlanguage-link-target"><span>Hrvatski</span></a></li><li class="interlanguage-link interwiki-it mw-list-item"><a href="https://it.wikipedia.org/wiki/Osteosarcoma" title="Osteosarcoma (italiano)" lang="it" hreflang="it" data-title="Osteosarcoma" data-language-autonym="Italiano" data-language-local-name="italiano" class="interlanguage-link-target"><span>Italiano</span></a></li><li class="interlanguage-link interwiki-ja mw-list-item"><a href="https://ja.wikipedia.org/wiki/%E9%AA%A8%E8%82%89%E8%85%AB" title="骨肉腫 (japonés)" lang="ja" hreflang="ja" data-title="骨肉腫" data-language-autonym="日本語" data-language-local-name="japonés" class="interlanguage-link-target"><span>日本語</span></a></li><li class="interlanguage-link interwiki-ko mw-list-item"><a href="https://ko.wikipedia.org/wiki/%EA%B3%A8%EC%9C%A1%EC%A2%85" title="골육종 (coreano)" lang="ko" hreflang="ko" data-title="골육종" data-language-autonym="한국어" data-language-local-name="coreano" class="interlanguage-link-target"><span>한국어</span></a></li><li class="interlanguage-link interwiki-la mw-list-item"><a href="https://la.wikipedia.org/wiki/Osteosarcoma" title="Osteosarcoma (latín)" lang="la" hreflang="la" data-title="Osteosarcoma" data-language-autonym="Latina" data-language-local-name="latín" class="interlanguage-link-target"><span>Latina</span></a></li><li class="interlanguage-link interwiki-lt mw-list-item"><a href="https://lt.wikipedia.org/wiki/Osteosarkoma" title="Osteosarkoma (lituano)" lang="lt" hreflang="lt" data-title="Osteosarkoma" data-language-autonym="Lietuvių" data-language-local-name="lituano" class="interlanguage-link-target"><span>Lietuvių</span></a></li><li class="interlanguage-link interwiki-ms mw-list-item"><a href="https://ms.wikipedia.org/wiki/Osteosarkoma" title="Osteosarkoma (malayo)" lang="ms" hreflang="ms" data-title="Osteosarkoma" data-language-autonym="Bahasa Melayu" data-language-local-name="malayo" class="interlanguage-link-target"><span>Bahasa Melayu</span></a></li><li class="interlanguage-link interwiki-new mw-list-item"><a href="https://new.wikipedia.org/wiki/%E0%A4%93%E0%A4%B8%E0%A5%8D%E0%A4%9F%E0%A4%BF%E0%A4%AF%E0%A5%8B%E0%A4%B8%E0%A4%BE%E0%A4%B0%E0%A5%8D%E0%A4%95%E0%A5%8B%E0%A4%AE%E0%A4%BE" title="ओस्टियोसार्कोमा (nevarí)" lang="new" hreflang="new" data-title="ओस्टियोसार्कोमा" data-language-autonym="नेपाल भाषा" data-language-local-name="nevarí" class="interlanguage-link-target"><span>नेपाल भाषा</span></a></li><li class="interlanguage-link interwiki-nl mw-list-item"><a href="https://nl.wikipedia.org/wiki/Osteosarcoom" title="Osteosarcoom (neerlandés)" lang="nl" hreflang="nl" data-title="Osteosarcoom" data-language-autonym="Nederlands" data-language-local-name="neerlandés" class="interlanguage-link-target"><span>Nederlands</span></a></li><li class="interlanguage-link interwiki-or mw-list-item"><a href="https://or.wikipedia.org/wiki/%E0%AC%93%E0%AC%B7%E0%AD%8D%E0%AC%9F%E0%AC%BF%E0%AC%93%E0%AC%B8%E0%AC%BE%E0%AC%B0%E0%AD%8D%E0%AC%95%E0%AD%8B%E0%AC%AE%E0%AC%BE" title="ଓଷ୍ଟିଓସାର୍କୋମା (oriya)" lang="or" hreflang="or" data-title="ଓଷ୍ଟିଓସାର୍କୋମା" data-language-autonym="ଓଡ଼ିଆ" data-language-local-name="oriya" class="interlanguage-link-target"><span>ଓଡ଼ିଆ</span></a></li><li class="interlanguage-link interwiki-pl badge-Q17437796 badge-featuredarticle mw-list-item" title="artículo destacado"><a href="https://pl.wikipedia.org/wiki/Kostniakomi%C4%99sak" title="Kostniakomięsak (polaco)" lang="pl" hreflang="pl" data-title="Kostniakomięsak" data-language-autonym="Polski" data-language-local-name="polaco" class="interlanguage-link-target"><span>Polski</span></a></li><li class="interlanguage-link interwiki-pt mw-list-item"><a href="https://pt.wikipedia.org/wiki/Osteossarcoma" title="Osteossarcoma (portugués)" lang="pt" hreflang="pt" data-title="Osteossarcoma" data-language-autonym="Português" data-language-local-name="portugués" class="interlanguage-link-target"><span>Português</span></a></li><li class="interlanguage-link interwiki-ru mw-list-item"><a href="https://ru.wikipedia.org/wiki/%D0%9E%D1%81%D1%82%D0%B5%D0%BE%D0%B3%D0%B5%D0%BD%D0%BD%D0%B0%D1%8F_%D1%81%D0%B0%D1%80%D0%BA%D0%BE%D0%BC%D0%B0" title="Остеогенная саркома (ruso)" lang="ru" hreflang="ru" data-title="Остеогенная саркома" data-language-autonym="Русский" data-language-local-name="ruso" class="interlanguage-link-target"><span>Русский</span></a></li><li class="interlanguage-link interwiki-sk mw-list-item"><a href="https://sk.wikipedia.org/wiki/Osteosark%C3%B3m" title="Osteosarkóm (eslovaco)" lang="sk" hreflang="sk" data-title="Osteosarkóm" data-language-autonym="Slovenčina" data-language-local-name="eslovaco" class="interlanguage-link-target"><span>Slovenčina</span></a></li><li class="interlanguage-link interwiki-sr mw-list-item"><a href="https://sr.wikipedia.org/wiki/%D0%9E%D1%81%D1%82%D0%B5%D0%BE%D1%81%D0%B0%D1%80%D0%BA%D0%BE%D0%BC" title="Остеосарком (serbio)" lang="sr" hreflang="sr" data-title="Остеосарком" data-language-autonym="Српски / srpski" data-language-local-name="serbio" class="interlanguage-link-target"><span>Српски / srpski</span></a></li><li class="interlanguage-link interwiki-sv mw-list-item"><a href="https://sv.wikipedia.org/wiki/Osteosarkom" title="Osteosarkom (sueco)" lang="sv" hreflang="sv" data-title="Osteosarkom" data-language-autonym="Svenska" data-language-local-name="sueco" class="interlanguage-link-target"><span>Svenska</span></a></li><li class="interlanguage-link interwiki-tr mw-list-item"><a href="https://tr.wikipedia.org/wiki/Osteosarkom" title="Osteosarkom (turco)" lang="tr" hreflang="tr" data-title="Osteosarkom" data-language-autonym="Türkçe" data-language-local-name="turco" class="interlanguage-link-target"><span>Türkçe</span></a></li><li class="interlanguage-link interwiki-uk mw-list-item"><a href="https://uk.wikipedia.org/wiki/%D0%9E%D1%81%D1%82%D0%B5%D0%BE%D0%B3%D0%B5%D0%BD%D0%BD%D0%B0_%D1%81%D0%B0%D1%80%D0%BA%D0%BE%D0%BC%D0%B0" title="Остеогенна саркома (ucraniano)" lang="uk" hreflang="uk" data-title="Остеогенна саркома" data-language-autonym="Українська" data-language-local-name="ucraniano" class="interlanguage-link-target"><span>Українська</span></a></li><li class="interlanguage-link interwiki-ur mw-list-item"><a href="https://ur.wikipedia.org/wiki/%D8%B9%D8%B8%D9%85%DB%8C_%D9%84%D8%AD%D9%85%D9%88%D9%85%DB%81" title="عظمی لحمومہ (urdu)" lang="ur" hreflang="ur" data-title="عظمی لحمومہ" data-language-autonym="اردو" data-language-local-name="urdu" class="interlanguage-link-target"><span>اردو</span></a></li><li class="interlanguage-link interwiki-vi mw-list-item"><a href="https://vi.wikipedia.org/wiki/U_x%C6%B0%C6%A1ng_%C3%A1c_t%C3%ADnh" title="U xương ác tính (vietnamita)" lang="vi" hreflang="vi" data-title="U xương ác tính" data-language-autonym="Tiếng Việt" data-language-local-name="vietnamita" class="interlanguage-link-target"><span>Tiếng Việt</span></a></li><li class="interlanguage-link interwiki-zh mw-list-item"><a href="https://zh.wikipedia.org/wiki/%E9%AA%A8%E8%82%89%E7%98%A4" title="骨肉瘤 (chino)" lang="zh" hreflang="zh" data-title="骨肉瘤" data-language-autonym="中文" data-language-local-name="chino" class="interlanguage-link-target"><span>中文</span></a></li> </ul> <div class="after-portlet after-portlet-lang"><span class="wb-langlinks-edit wb-langlinks-link"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q549534#sitelinks-wikipedia" title="Editar enlaces interlingüísticos" class="wbc-editpage">Editar enlaces</a></span></div> </div> </div> </div> </header> <div class="vector-page-toolbar"> <div 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<div class="vector-dropdown-content"> <div id="vector-page-tools-unpinned-container" class="vector-unpinned-container"> <div id="vector-page-tools" class="vector-page-tools vector-pinnable-element"> <div class="vector-pinnable-header vector-page-tools-pinnable-header vector-pinnable-header-unpinned" data-feature-name="page-tools-pinned" data-pinnable-element-id="vector-page-tools" data-pinned-container-id="vector-page-tools-pinned-container" data-unpinned-container-id="vector-page-tools-unpinned-container" > <div class="vector-pinnable-header-label">Herramientas</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-page-tools.pin">mover a la barra lateral</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-page-tools.unpin">ocultar</button> </div> <div id="p-cactions" class="vector-menu mw-portlet mw-portlet-cactions 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data-feature-name="appearance-pinned" data-pinnable-element-id="vector-appearance" data-pinned-container-id="vector-appearance-pinned-container" data-unpinned-container-id="vector-appearance-unpinned-container" > <div class="vector-pinnable-header-label">Apariencia</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-appearance.pin">mover a la barra lateral</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-appearance.unpin">ocultar</button> </div> </div> </div> </nav> </div> </div> <div id="bodyContent" class="vector-body" aria-labelledby="firstHeading" data-mw-ve-target-container> <div class="vector-body-before-content"> <div class="mw-indicators"> </div> <div id="siteSub" class="noprint">De Wikipedia, la enciclopedia libre</div> </div> <div id="contentSub"><div id="mw-content-subtitle"></div></div> <div id="mw-content-text" class="mw-body-content"><div class="mw-content-ltr mw-parser-output" lang="es" dir="ltr"><style data-mw-deduplicate="TemplateStyles:r157776694">.mw-parser-output .infobox .imagen{max-width:100%;margin:0 auto}.mw-parser-output .infobox .imagen img{max-width:100%;height:auto}.mw-parser-output .infobox .mw-kartographer-container .thumbinner,.mw-parser-output .infobox .mw-kartographer-map{box-sizing:border-box;width:100%!important}body.skin-timeless .mw-parser-output .infobox .imagen a.image>img{max-width:100%!important;height:auto!important}</style><table class="infobox" style="width:22.7em; line-height: 1.4em; text-align:left; padding:.23em;"><tbody><tr><th colspan="3" class="cabecera medicina" style="text-align:center;background-color:#DCDCDC;color:inherit;">Osteosarcoma</th></tr><tr><td colspan="3" class="imagen" style="text-align:center;"> <span typeof="mw:File"><a href="/wiki/Archivo:Osteosarcoma.jpg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/5/5b/Osteosarcoma.jpg/320px-Osteosarcoma.jpg" decoding="async" width="320" height="213" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/5/5b/Osteosarcoma.jpg/480px-Osteosarcoma.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/5/5b/Osteosarcoma.jpg/640px-Osteosarcoma.jpg 2x" data-file-width="2136" data-file-height="1424" /></a></span><br /><div style="display:inline;font-size:85%;">Microfotografía de un <b>osteosarcoma</b> con células gigantes multinucleadas similares a <a href="/wiki/Osteoclasto" title="Osteoclasto">osteoclastos</a>.</div></td></tr><tr><th scope="row" style="text-align:left;"><a href="/wiki/Especialidades_m%C3%A9dicas" title="Especialidades médicas">Especialidad</a></th><td colspan="2"> <a href="/wiki/Oncolog%C3%ADa" title="Oncología">oncología</a></td></tr><tr><td class="noprint" colspan="3" style="text-align:left;"><div class="plainlinks wikidata-link" style="font-size: 0.85em">[<a href="https://www.wikidata.org/wiki/Q549534" class="extiw" title="d:Q549534">editar datos en Wikidata</a>]</div></td></tr></tbody></table> <p>El <b>osteosarcoma</b> es un <a href="/wiki/C%C3%A1ncer" title="Cáncer">cáncer</a> óseo que aparece por lo general en las metáfisis de un hueso largo; también llamado <b>osteoma sarcomatoso</b>.<sup id="cite_ref-1" class="reference separada"><a href="#cite_note-1"><span class="corchete-llamada">[</span>1<span class="corchete-llamada">]</span></a></sup><sup id="cite_ref-2" class="reference separada"><a href="#cite_note-2"><span class="corchete-llamada">[</span>2<span class="corchete-llamada">]</span></a></sup> </p><p>Se trata de una <a href="/wiki/Neoplasia" title="Neoplasia">neoplasia</a> <a href="/wiki/C%C3%A1ncer" title="Cáncer">maligna</a> que procede de células del <a href="/wiki/Mes%C3%A9nquima" class="mw-redirect" title="Mesénquima">mesénquima</a> (es decir, un <a href="/wiki/Sarcoma" title="Sarcoma">sarcoma</a>).<sup id="cite_ref-3" class="reference separada"><a href="#cite_note-3"><span class="corchete-llamada">[</span>3<span class="corchete-llamada">]</span></a></sup> Estas células presentan una diferenciación <a href="/wiki/Osteoblasto" title="Osteoblasto">osteoblástica</a> hacia <a href="/wiki/Osteoide" title="Osteoide">osteoides</a> malignos. Se trata de la forma <a href="/wiki/Histolog%C3%ADa" title="Histología">histológica</a> más frecuente de <a href="/wiki/C%C3%A1ncer_%C3%B3seo_primario" title="Cáncer óseo primario">cáncer óseo</a>.<sup id="cite_ref-OttavianiJaffe_4-0" class="reference separada"><a href="#cite_note-OttavianiJaffe-4"><span class="corchete-llamada">[</span>4<span class="corchete-llamada">]</span></a></sup> </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="Signos_y_síntomas"><span id="Signos_y_s.C3.ADntomas"></span>Signos y síntomas</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Osteosarcoma&action=edit&section=1" title="Editar sección: Signos y síntomas"><span>editar</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Algunos adolescentes que practican deportes con frecuencia, se quejan de dolor en el fémur inferior o inmediatamente debajo de la rodilla. A veces una fractura repentina es el primer síntoma, porque el hueso afectado no es tan fuerte como el hueso normal y puede tener una <a href="/w/index.php?title=Fractura_patol%C3%B3gica&action=edit&redlink=1" class="new" title="Fractura patológica (aún no redactado)">fractura anormal con trauma leve</a>. En casos de tumores más profundos que no están tan cerca de la piel, como los que se originan en la pelvis, la hinchazón localizada puede no ser obvia.<sup id="cite_ref-5" class="reference separada"><a href="#cite_note-5"><span class="corchete-llamada">[</span>5<span class="corchete-llamada">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Incidencia">Incidencia</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Osteosarcoma&action=edit&section=2" title="Editar sección: Incidencia"><span>editar</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Se trata del octavo tipo más frecuente de <a href="/wiki/C%C3%A1ncer_infantil" title="Cáncer infantil">cáncer infantil</a>: representa el 2,4% de los casos de cáncer pediátrico, y aproximadamente el 20% de todos los cánceres de huesos primarios.<sup id="cite_ref-6" class="reference separada"><a href="#cite_note-6"><span class="corchete-llamada">[</span>6<span class="corchete-llamada">]</span></a></sup> Según <a href="/wiki/Epidemiolog%C3%ADa" title="Epidemiología">datos epidemiológicos</a> de Estados Unidos, la prevalencia es ligeramente mayor en hombres que en mujeres.<sup id="cite_ref-OttavianiJaffe_4-1" class="reference separada"><a href="#cite_note-OttavianiJaffe-4"><span class="corchete-llamada">[</span>4<span class="corchete-llamada">]</span></a></sup> </p><p>Su localización más habitual es la región de la <a href="/wiki/Met%C3%A1fisis" title="Metáfisis">metáfisis</a> de huesos tubulares largos; así, el 42% se dan en el <a href="/wiki/F%C3%A9mur" title="Fémur">fémur</a>, el 19% en la <a href="/wiki/Tibia" title="Tibia">tibia</a> y el 10% en el <a href="/wiki/H%C3%BAmero" title="Húmero">húmero</a>. No obstante, un 8% de los casos se dan en <a href="/wiki/Cr%C3%A1neo" title="Cráneo">cráneo</a> y <a href="/wiki/Mand%C3%ADbula" title="Mandíbula">mandíbula</a>, y un 8% en la <a href="/wiki/Pelvis" title="Pelvis">pelvis</a>.<sup id="cite_ref-OttavianiJaffe_4-2" class="reference separada"><a href="#cite_note-OttavianiJaffe-4"><span class="corchete-llamada">[</span>4<span class="corchete-llamada">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Causas">Causas</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Osteosarcoma&action=edit&section=3" title="Editar sección: Causas"><span>editar</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Varios grupos de investigación están investigando las células madre del cáncer<sup id="cite_ref-7" class="reference separada"><a href="#cite_note-7"><span class="corchete-llamada">[</span>7<span class="corchete-llamada">]</span></a></sup> y su potencial para causar tumores junto con genes y proteínas causantes en diferentes fenotipos.<sup id="cite_ref-8" class="reference separada"><a href="#cite_note-8"><span class="corchete-llamada">[</span>8<span class="corchete-llamada">]</span></a></sup><sup id="cite_ref-9" class="reference separada"><a href="#cite_note-9"><span class="corchete-llamada">[</span>9<span class="corchete-llamada">]</span></a></sup> La <a href="/wiki/Radioterapia" title="Radioterapia">radioterapia</a> por una enfermedad no relacionada puede ser una causa rara.<sup id="cite_ref-10" class="reference separada"><a href="#cite_note-10"><span class="corchete-llamada">[</span>10<span class="corchete-llamada">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Supervivencia">Supervivencia</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Osteosarcoma&action=edit&section=4" title="Editar sección: Supervivencia"><span>editar</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Los neoplasmas malignos de huesos y articulaciones tienen un peso total desconocido en la mortalidad por cáncer infantil. La tasa de mortalidad muestra una tendencia a disminuir un 1,3% aproximadamente al año. A largo plazo, la probabilidad de sobrevivir a un osteosarcoma se ha incrementado notablemente durante finales del siglo <span style="font-variant:small-caps;text-transform:lowercase">XX</span>, situándose en 2009 en aproximadamente un 15%.<sup id="cite_ref-OttavianiJaffe_4-3" class="reference separada"><a href="#cite_note-OttavianiJaffe-4"><span class="corchete-llamada">[</span>4<span class="corchete-llamada">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Referencias">Referencias</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Osteosarcoma&action=edit&section=5" title="Editar sección: Referencias"><span>editar</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="listaref" style="-moz-column-count:2; -webkit-column-count:2; column-count:2; list-style-type: decimal;"><ol class="references"> <li id="cite_note-1"><span class="mw-cite-backlink"><a href="#cite_ref-1">↑</a></span> <span class="reference-text"><a rel="nofollow" class="external text" href="http://sarcomahelp.org/translate/es-osteosarcoma.html">Osteosarcoma - en castellano</a></span> </li> <li id="cite_note-2"><span class="mw-cite-backlink"><a href="#cite_ref-2">↑</a></span> <span class="reference-text">Melloni (1983), Diccionario Médico Ilustrado, Barcelona: Reverté <a href="/wiki/Especial:FuentesDeLibros/8429155481" class="internal mw-magiclink-isbn">ISBN 84-291-5548-1</a></span> </li> <li id="cite_note-3"><span class="mw-cite-backlink"><a href="#cite_ref-3">↑</a></span> <span class="reference-text"><span id="CITAREFLuetke_A,_Meyers_PA,_Lewis_A,_Juergens_H2014" class="citation publicación">Luetke A, Meyers PA, Lewis A, Juergens H (2014). «Osteosarcoma treatment—where do we stand? A state of the art review». <i>Cancer Treat Rev</i> <span style="color:var(--color-subtle, #555 );">(en inglés)</span> <b>40</b> (4): 523-532. <small><a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/24345772">24345772</a></small>. <small><a href="/wiki/Digital_object_identifier" class="mw-redirect" title="Digital object identifier">doi</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1016%2Fj.ctrv.2013.11.006">10.1016/j.ctrv.2013.11.006</a></small>.</span><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fes.wikipedia.org%3AOsteosarcoma&rft.atitle=Osteosarcoma+treatment%E2%80%94where+do+we+stand%3F+A+state+of+the+art+review&rft.au=Luetke+A%2C+Meyers+PA%2C+Lewis+A%2C+Juergens+H&rft.aulast=Luetke+A%2C+Meyers+PA%2C+Lewis+A%2C+Juergens+H&rft.date=2014&rft.genre=article&rft.issue=4&rft.jtitle=Cancer+Treat+Rev&rft.pages=523-532&rft.volume=40&rft_id=info%3Adoi%2F10.1016%2Fj.ctrv.2013.11.006&rft_id=info%3Apmid%2F24345772&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-OttavianiJaffe-4"><span class="mw-cite-backlink">↑ <a href="#cite_ref-OttavianiJaffe_4-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-OttavianiJaffe_4-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-OttavianiJaffe_4-2"><sup><i><b>c</b></i></sup></a> <a href="#cite_ref-OttavianiJaffe_4-3"><sup><i><b>d</b></i></sup></a></span> <span class="reference-text"><span id="CITAREFOttaviani_G.,_Jaffe_N.2009" class="citation libro">Ottaviani G., Jaffe N. (2009). <i>The epidemiology of osteosarcoma. In: Jaffe N. et al. "Pediatric and Adolescent Osteosarcoma"</i>. New York: Springer. <small><a href="/wiki/ISBN" title="ISBN">ISBN</a> <a href="/wiki/Especial:FuentesDeLibros/978-1-4419-0283-2" title="Especial:FuentesDeLibros/978-1-4419-0283-2">978-1-4419-0283-2</a></small>. <small><a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/20213383">20213383</a></small>. <small><a href="/wiki/Digital_object_identifier" class="mw-redirect" title="Digital object identifier">doi</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1007%2F978-1-4419-0284-9_1">10.1007/978-1-4419-0284-9_1</a></small>.</span><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fes.wikipedia.org%3AOsteosarcoma&rft.au=Ottaviani+G.%2C+Jaffe+N.&rft.aulast=Ottaviani+G.%2C+Jaffe+N.&rft.btitle=The+epidemiology+of+osteosarcoma.+In%3A+Jaffe+N.+et+al.+%22Pediatric+and+Adolescent+Osteosarcoma%22&rft.date=2009&rft.genre=book&rft.isbn=978-1-4419-0283-2&rft.place=New+York&rft.pub=Springer&rft_id=info%3Adoi%2F10.1007%2F978-1-4419-0284-9_1&rft_id=info%3Apmid%2F20213383&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-5"><span class="mw-cite-backlink"><a href="#cite_ref-5">↑</a></span> <span class="reference-text"><span class="citation web"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0002616/">«Osteosarcoma»</a>. <i>US National Library of Medicine</i> <span style="color:var(--color-subtle, #555 );">(en inglés)</span>. PubMed Health. 2013<span class="reference-accessdate">. Consultado el 5 de diciembre de 2017</span>.</span><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fes.wikipedia.org%3AOsteosarcoma&rft.atitle=Osteosarcoma&rft.date=2013&rft.genre=article&rft.jtitle=US+National+Library+of+Medicine&rft.pub=PubMed+Health&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpubmedhealth%2FPMH0002616%2F&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-6"><span class="mw-cite-backlink"><a href="#cite_ref-6">↑</a></span> <span class="reference-text"><span class="citation web"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0002616/">«Osteosarcoma»</a>. <i>US National Library of Medicine</i> <span style="color:var(--color-subtle, #555 );">(en inglés)</span>. PubMed Health. 2013<span class="reference-accessdate">. Consultado el 5 de diciembre de 2017</span>.</span><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fes.wikipedia.org%3AOsteosarcoma&rft.atitle=Osteosarcoma&rft.date=2013&rft.genre=article&rft.jtitle=US+National+Library+of+Medicine&rft.pub=PubMed+Health&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpubmedhealth%2FPMH0002616%2F&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-7"><span class="mw-cite-backlink"><a href="#cite_ref-7">↑</a></span> <span class="reference-text"><span id="CITAREFOsuna_D,_de_Alava_E2009" class="citation publicación">Osuna D, de Alava E (2009). «Molecular pathology of sarcomas». <i>Rev Recent Clin Trials</i> <b>4</b> (1): 12-26. <small><a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/19149759">19149759</a></small>. <small><a href="/wiki/Digital_object_identifier" class="mw-redirect" title="Digital object identifier">doi</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.2174%2F157488709787047585">10.2174/157488709787047585</a></small>.</span><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fes.wikipedia.org%3AOsteosarcoma&rft.atitle=Molecular+pathology+of+sarcomas&rft.au=Osuna+D%2C+de+Alava+E&rft.aulast=Osuna+D%2C+de+Alava+E&rft.date=2009&rft.genre=article&rft.issue=1&rft.jtitle=Rev+Recent+Clin+Trials&rft.pages=12-26&rft.volume=4&rft_id=info%3Adoi%2F10.2174%2F157488709787047585&rft_id=info%3Apmid%2F19149759&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-8"><span class="mw-cite-backlink"><a href="#cite_ref-8">↑</a></span> <span class="reference-text"><span id="CITAREFSharmaCintiCapobianco2017" class="citation publicación">Sharma, Ankush; Cinti, Caterina; Capobianco, Enrico (2017). <a rel="nofollow" class="external text" href="http://journal.frontiersin.org/article/10.3389/fimmu.2017.00918/full">«Multitype Network-Guided Target Controllability in Phenotypically Characterized Osteosarcoma: Role of Tumor Microenvironment»</a>. <i>Frontiers in Immunology</i> <span style="color:var(--color-subtle, #555 );">(en inglés)</span> <b>8</b>. <small><a href="/wiki/ISSN" class="mw-redirect" title="ISSN">ISSN</a> <a rel="nofollow" class="external text" href="//portal.issn.org/resource/issn/1664-3224">1664-3224</a></small>. <small><a href="/wiki/Digital_object_identifier" class="mw-redirect" title="Digital object identifier">doi</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.3389%2Ffimmu.2017.00918">10.3389/fimmu.2017.00918</a></small>.</span><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fes.wikipedia.org%3AOsteosarcoma&rft.atitle=Multitype+Network-Guided+Target+Controllability+in+Phenotypically+Characterized+Osteosarcoma%3A+Role+of+Tumor+Microenvironment&rft.au=Capobianco%2C+Enrico&rft.au=Cinti%2C+Caterina&rft.au=Sharma%2C+Ankush&rft.aufirst=Ankush&rft.aulast=Sharma&rft.date=2017&rft.genre=article&rft.issn=1664-3224&rft.jtitle=Frontiers+in+Immunology&rft.volume=8&rft_id=http%3A%2F%2Fjournal.frontiersin.org%2Farticle%2F10.3389%2Ffimmu.2017.00918%2Ffull&rft_id=info%3Adoi%2F10.3389%2Ffimmu.2017.00918&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-9"><span class="mw-cite-backlink"><a href="#cite_ref-9">↑</a></span> <span class="reference-text"><span id="CITAREFSharmaCapobianco2017" class="citation publicación">Sharma, Ankush; Capobianco, Enrico (2017). <a rel="nofollow" class="external text" href="http://insights.sagepub.com/immuno-oncology-integrative-networks-elucidating-the-influences-of-ost-article-a6476">«Immuno-Oncology Integrative Networks: Elucidating the Influences of Osteosarcoma Phenotypes»</a>. <i>Cancer Informatics</i> <span style="color:var(--color-subtle, #555 );">(en inglés)</span> <b>16</b>. <small><a href="/wiki/ISSN" class="mw-redirect" title="ISSN">ISSN</a> <a rel="nofollow" class="external text" href="//portal.issn.org/resource/issn/1176-9351">1176-9351</a></small>. <small><a href="/wiki/Digital_object_identifier" class="mw-redirect" title="Digital object identifier">doi</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1177%2F1176935117721691">10.1177/1176935117721691</a></small>.</span><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fes.wikipedia.org%3AOsteosarcoma&rft.atitle=Immuno-Oncology+Integrative+Networks%3A+Elucidating+the+Influences+of+Osteosarcoma+Phenotypes&rft.au=Capobianco%2C+Enrico&rft.au=Sharma%2C+Ankush&rft.aufirst=Ankush&rft.aulast=Sharma&rft.date=2017&rft.genre=article&rft.issn=1176-9351&rft.jtitle=Cancer+Informatics&rft.volume=16&rft_id=http%3A%2F%2Finsights.sagepub.com%2Fimmuno-oncology-integrative-networks-elucidating-the-influences-of-ost-article-a6476&rft_id=info%3Adoi%2F10.1177%2F1176935117721691&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-10"><span class="mw-cite-backlink"><a href="#cite_ref-10">↑</a></span> <span class="reference-text"><span id="CITAREFDhaliwal_J,_Sumathi_VP,_Grimer_RJ20_de_diciembre_de_2009" class="citation publicación">Dhaliwal J, Sumathi VP, Grimer RJ (20 de diciembre de 2009). <a rel="nofollow" class="external text" href="http://www.grandroundsjournal.com/articles/gr100003/gr100003.pdf">«Radiation-induced periosteal osteosarcoma»</a>. <i>Grand Rounds</i> <span style="color:var(--color-subtle, #555 );">(en inglés)</span> <b>10</b>: 13-18. <small><a href="/wiki/Digital_object_identifier" class="mw-redirect" title="Digital object identifier">doi</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1102%2F1470-5206.2010.0003">10.1102/1470-5206.2010.0003</a></small>.</span><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fes.wikipedia.org%3AOsteosarcoma&rft.atitle=Radiation-induced+periosteal+osteosarcoma&rft.au=Dhaliwal+J%2C+Sumathi+VP%2C+Grimer+RJ&rft.aulast=Dhaliwal+J%2C+Sumathi+VP%2C+Grimer+RJ&rft.date=20+de+diciembre+de+2009&rft.genre=article&rft.jtitle=Grand+Rounds&rft.pages=13-18&rft.volume=10&rft_id=http%3A%2F%2Fwww.grandroundsjournal.com%2Farticles%2Fgr100003%2Fgr100003.pdf&rft_id=info%3Adoi%2F10.1102%2F1470-5206.2010.0003&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> </ol></div> <style data-mw-deduplicate="TemplateStyles:r161257576">.mw-parser-output .mw-authority-control{margin-top:1.5em}.mw-parser-output .mw-authority-control .navbox table{margin:0}.mw-parser-output .mw-authority-control .navbox hr:last-child{display:none}.mw-parser-output .mw-authority-control .navbox+.mw-mf-linked-projects{display:none}.mw-parser-output .mw-authority-control 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.navbox-list{border-color:#202122!important}html.skin-theme-clientpref-os .mw-parser-output .mw-authority-control .navbox th{background-color:#27292d!important}}</style><div class="mw-authority-control"><div role="navigation" class="navbox" aria-label="Navbox" style="width: inherit;padding:3px"><table class="hlist navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="row" class="navbox-group" style="width: 12%; text-align:center;"><a href="/wiki/Control_de_autoridades" title="Control de autoridades">Control de autoridades</a></th><td class="navbox-list navbox-odd" style="text-align:left;border-left-width:2px;border-left-style:solid;width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><b>Proyectos Wikimedia</b></li> <li><span style="white-space:nowrap;"><span typeof="mw:File"><a href="/wiki/Wikidata" title="Wikidata"><img alt="Wd" src="//upload.wikimedia.org/wikipedia/commons/thumb/f/ff/Wikidata-logo.svg/20px-Wikidata-logo.svg.png" decoding="async" width="20" height="11" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/f/ff/Wikidata-logo.svg/30px-Wikidata-logo.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/f/ff/Wikidata-logo.svg/40px-Wikidata-logo.svg.png 2x" data-file-width="1050" data-file-height="590" /></a></span> Datos:</span> <span class="uid"><a href="https://www.wikidata.org/wiki/Q549534" class="extiw" title="wikidata:Q549534">Q549534</a></span></li> <li><span style="white-space:nowrap;"><span typeof="mw:File"><a href="/wiki/Wikimedia_Commons" title="Commonscat"><img alt="Commonscat" src="//upload.wikimedia.org/wikipedia/commons/thumb/4/4a/Commons-logo.svg/15px-Commons-logo.svg.png" decoding="async" width="15" height="20" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/4/4a/Commons-logo.svg/23px-Commons-logo.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/4/4a/Commons-logo.svg/30px-Commons-logo.svg.png 2x" data-file-width="1024" data-file-height="1376" /></a></span> Multimedia:</span> <span class="uid"><span class="plainlinks"><a class="external text" href="https://commons.wikimedia.org/wiki/Category:Osteosarcoma">Osteosarcoma</a></span> / <span class="plainlinks"><a class="external text" href="https://commons.wikimedia.org/wiki/Special:MediaSearch?type=image&search=%22Q549534%22">Q549534</a></span></span></li></ul> <hr /> <ul><li><b>Identificadores</b></li> <li><span style="white-space:nowrap;"><a href="/wiki/Biblioteca_Nacional_de_Francia" title="Biblioteca Nacional de Francia">BNF</a>:</span> <span class="uid"><a rel="nofollow" class="external text" href="https://catalogue.bnf.fr/ark:/12148/cb12412520t">12412520t</a> <a rel="nofollow" class="external text" href="http://data.bnf.fr/ark:/12148/cb12412520t">(data)</a></span></li> <li><span style="white-space:nowrap;"><a href="/wiki/Gemeinsame_Normdatei" title="Gemeinsame Normdatei">GND</a>:</span> <span class="uid"><a rel="nofollow" class="external text" href="https://d-nb.info/gnd/4172929-8">4172929-8</a></span></li> <li><span style="white-space:nowrap;"><a href="/wiki/Library_of_Congress_Control_Number" title="Library of Congress Control Number">LCCN</a>:</span> <span class="uid"><a rel="nofollow" class="external text" href="https://id.loc.gov/authorities/sh85095987">sh85095987</a></span></li> <li><span style="white-space:nowrap;"><a href="/wiki/Biblioteca_Nacional_de_Israel" title="Biblioteca Nacional de Israel">NLI</a>:</span> <span class="uid"><a rel="nofollow" class="external text" href="http://olduli.nli.org.il/F/?func=find-b&local_base=NLX10&find_code=UID&request=987007553341605171">987007553341605171</a></span></li> <li><b>Diccionarios y enciclopedias</b></li> <li><span style="white-space:nowrap;"><a href="/wiki/Enciclopedia_Brit%C3%A1nica" title="Enciclopedia Británica">Britannica</a>:</span> <span class="uid"><a rel="nofollow" class="external text" href="https://www.britannica.com/science/osteosarcoma">url</a></span></li> <li><b>Identificadores médicos</b></li> <li><span style="white-space:nowrap;">DOID:</span> <span class="uid"><a rel="nofollow" class="external text" href="http://www.disease-ontology.org/?id=DOID:3347">DOID:3347</a></span></li> <li><span style="white-space:nowrap;"><a href="/wiki/CIE-11" title="CIE-11">CIE-11</a>:</span> <span class="uid"><a rel="nofollow" class="external text" href="https://icd.who.int/browse11/l-m/en#/http://id.who.int/icd/entity/823787853">XH1XF3</a></span></li> <li><span style="white-space:nowrap;"><a href="/wiki/CIE-10" title="CIE-10">CIE-10</a>:</span> <span class="uid"><a rel="nofollow" class="external text" href="https://icd.who.int/browse10/2019/en#/C40">C40</a></span></li> <li><span style="white-space:nowrap;"><a href="/wiki/CIE-9" title="CIE-9">CIE-9</a>:</span> <span class="uid"><a rel="nofollow" class="external text" href="http://www.icd9data.com/getICD9Code.ashx?icd9=170">170</a></span></li> <li><span style="white-space:nowrap;"><a href="/wiki/CIE-O" title="CIE-O">CIE-O</a>:</span> <span class="uid"><a rel="nofollow" class="external text" href="http://codes.iarc.fr/search.php?cx=009987501641899931167%3A2_7lsevqpdm&cof=FORID%3A9&ie=UTF-8&ie=ISO-8859-1&oe=ISO-8859-1&sa=&q=9180/3">9180/3</a></span></li> <li><span style="white-space:nowrap;"><a href="/wiki/Herencia_Mendeliana_en_el_Hombre" title="Herencia Mendeliana en el Hombre">OMIM</a>:</span> <span class="uid"><a rel="nofollow" class="external text" href="https://omim.org/entry/259500">259500</a></span></li> <li><span style="white-space:nowrap;"><a href="/wiki/Diseases_Database" title="Diseases Database">DiseasesDB</a>:</span> <span class="uid"><a rel="nofollow" class="external text" href="http://www.diseasesdatabase.com/ddb9392.htm">9392</a></span></li> <li><span style="white-space:nowrap;"><a href="/wiki/MedlinePlus" title="MedlinePlus">MedlinePlus</a>:</span> <span class="uid"><a rel="nofollow" class="external text" href="https://medlineplus.gov/spanish/ency/article/001650.htm">001650</a></span></li> <li><span style="white-space:nowrap;"><a href="/wiki/EMedicine" title="EMedicine">eMedicine</a>:</span> <span class="uid"><a rel="nofollow" class="external text" href="https://emedicine.medscape.com/article/988516-overview">988516</a></span></li> <li><span style="white-space:nowrap;"><a href="/wiki/Medical_Subject_Headings" title="Medical Subject Headings">MeSH</a>:</span> <span class="uid"><a rel="nofollow" class="external text" href="https://meshb.nlm.nih.gov/record/ui?ui=D012516">D012516</a></span></li> <li><span style="white-space:nowrap;"><a href="/wiki/Orphanet" title="Orphanet">Orphanet</a>:</span> <span class="uid"><a rel="nofollow" class="external text" href="https://www.orpha.net/en/disease/detail/668">668</a></span></li> <li><span style="white-space:nowrap;">UMLS:</span> <span class="uid"><a rel="nofollow" class="external text" href="https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI%20Metathesaurus&code=C0029463">C0029463</a></span></li> <li><b>Identificadores químicos</b></li> <li><span style="white-space:nowrap;"><a href="/wiki/KEGG" title="KEGG">KEGG</a>:</span> <span class="uid"><a rel="nofollow" class="external text" href="https://www.kegg.jp/entry/H00036">H00036</a></span></li></ul> </div></td></tr></tbody></table></div><div class="mw-mf-linked-projects hlist"> <ul><li><span style="white-space:nowrap;"><span typeof="mw:File"><a href="/wiki/Wikidata" title="Wikidata"><img alt="Wd" src="//upload.wikimedia.org/wikipedia/commons/thumb/f/ff/Wikidata-logo.svg/20px-Wikidata-logo.svg.png" decoding="async" width="20" height="11" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/f/ff/Wikidata-logo.svg/30px-Wikidata-logo.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/f/ff/Wikidata-logo.svg/40px-Wikidata-logo.svg.png 2x" data-file-width="1050" data-file-height="590" /></a></span> Datos:</span> <span class="uid"><a href="https://www.wikidata.org/wiki/Q549534" class="extiw" title="wikidata:Q549534">Q549534</a></span></li> <li><span style="white-space:nowrap;"><span typeof="mw:File"><a href="/wiki/Wikimedia_Commons" title="Commonscat"><img alt="Commonscat" src="//upload.wikimedia.org/wikipedia/commons/thumb/4/4a/Commons-logo.svg/15px-Commons-logo.svg.png" decoding="async" width="15" height="20" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/4/4a/Commons-logo.svg/23px-Commons-logo.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/4/4a/Commons-logo.svg/30px-Commons-logo.svg.png 2x" data-file-width="1024" data-file-height="1376" /></a></span> Multimedia:</span> <span class="uid"><span class="plainlinks"><a class="external text" href="https://commons.wikimedia.org/wiki/Category:Osteosarcoma">Osteosarcoma</a></span> / <span class="plainlinks"><a class="external text" href="https://commons.wikimedia.org/wiki/Special:MediaSearch?type=image&search=%22Q549534%22">Q549534</a></span></span></li></ul> </div></div>    </div><noscript><img src="https://login.wikimedia.org/wiki/Special:CentralAutoLogin/start?type=1x1&useformat=desktop" alt="" width="1" height="1" style="border: none; position: absolute;"></noscript> <div class="printfooter" data-nosnippet="">Obtenido de «<a dir="ltr" href="https://es.wikipedia.org/w/index.php?title=Osteosarcoma&oldid=157692027">https://es.wikipedia.org/w/index.php?title=Osteosarcoma&oldid=157692027</a>»</div></div> <div id="catlinks" class="catlinks" data-mw="interface"><div id="mw-normal-catlinks" class="mw-normal-catlinks"><a href="/wiki/Especial:Categor%C3%ADas" title="Especial:Categorías">Categorías</a>: <ul><li><a href="/wiki/Categor%C3%ADa:C%C3%A1ncer_%C3%B3seo" title="Categoría:Cáncer óseo">Cáncer óseo</a></li><li><a href="/wiki/Categor%C3%ADa:Enfermedades_pedi%C3%A1tricas" title="Categoría:Enfermedades pediátricas">Enfermedades pediátricas</a></li><li><a href="/wiki/Categor%C3%ADa:Enfermedades_de_felinos" title="Categoría:Enfermedades de felinos">Enfermedades de felinos</a></li><li><a href="/wiki/Categor%C3%ADa:Enfermedades_caninas" title="Categoría:Enfermedades caninas">Enfermedades caninas</a></li></ul></div><div id="mw-hidden-catlinks" class="mw-hidden-catlinks mw-hidden-cats-hidden">Categorías ocultas: <ul><li><a href="/wiki/Categor%C3%ADa:Wikipedia:P%C3%A1ginas_con_enlaces_m%C3%A1gicos_de_ISBN" title="Categoría:Wikipedia:Páginas con enlaces mágicos de ISBN">Wikipedia:Páginas con enlaces mágicos de ISBN</a></li><li><a href="/wiki/Categor%C3%ADa:Wikipedia:Art%C3%ADculos_destacados_en_la_Wikipedia_en_polaco" title="Categoría:Wikipedia:Artículos destacados en la Wikipedia en polaco">Wikipedia:Artículos destacados en la Wikipedia en 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