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therapies</title> <meta name="description" content="Search results for: combination therapies"> <meta name="keywords" content="combination therapies"> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1, maximum-scale=1, user-scalable=no"> <meta charset="utf-8"> <link href="https://cdn.waset.org/favicon.ico" type="image/x-icon" rel="shortcut icon"> <link href="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/css/bootstrap.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/plugins/fontawesome/css/all.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/css/site.css?v=150220211555" rel="stylesheet"> </head> <body> <header> <div class="container"> <nav class="navbar navbar-expand-lg navbar-light"> <a class="navbar-brand" href="https://waset.org"> <img src="https://cdn.waset.org/static/images/wasetc.png" alt="Open Science Research Excellence" title="Open Science Research Excellence" /> </a> <button class="d-block d-lg-none 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action="https://publications.waset.org/abstracts/search"> <div id="custom-search-input"> <div class="input-group"> <i class="fas fa-search"></i> <input type="text" class="search-query" name="q" placeholder="Author, Title, Abstract, Keywords" value="combination therapies"> <input type="submit" class="btn_search" value="Search"> </div> </div> </form> </div> </div> <div class="row mt-3"> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Commenced</strong> in January 2007</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Frequency:</strong> Monthly</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Edition:</strong> International</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Paper Count:</strong> 3407</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: combination therapies</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3407</span> From Past to Present Awareness about Complementary Therapies</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Olcay%20%C3%87am">Olcay Çam</a>, <a href="https://publications.waset.org/abstracts/search?q=Ay%C5%9Feg%C3%BCl%20Bilge"> Ayşegül Bilge</a>, <a href="https://publications.waset.org/abstracts/search?q=Merve%20U%C4%9Furyol"> Merve Uğuryol</a>, <a href="https://publications.waset.org/abstracts/search?q=Hacer%20Demirkol"> Hacer Demirkol</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Complementary and alternative medicine are important for human health. It has stood out that from past to present people have resorted to particularly Turkish bath houses, cupping therapy, mud bath, hirudotheraphy and healing waters for the purpose of recovering from diseases and refresh their souls. Now, methods such as herbal treatments, massage, aromatherapy, prayer, meditation, yoga and thermal springs have been recently observed to be the most frequently used complementary therapies in Turkey. These methods are not known by people exactly. As a result, complementary therapies are applied along with the modern therapies in Turkey, we are considered to be effective in maintaining and improving individuals’ health. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=complementary%20therapy" title="complementary therapy">complementary therapy</a>, <a href="https://publications.waset.org/abstracts/search?q=health" title=" health"> health</a>, <a href="https://publications.waset.org/abstracts/search?q=health%20services" title=" health services"> health services</a>, <a href="https://publications.waset.org/abstracts/search?q=modern%20therapies" title=" modern therapies"> modern therapies</a> </p> <a href="https://publications.waset.org/abstracts/48139/from-past-to-present-awareness-about-complementary-therapies" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/48139.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">279</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3406</span> Cochlear Implants and the Emerging Therapies for Managing Hearing Loss</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Hesham%20Kozou">Hesham Kozou</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Sensorineural hearing loss (SNHL) poses a significant challenge due to limited access to the inner ear for therapies. Emerging treatments such as regenerative, genetic, and pharmacotherapies offer hope for addressing this condition. This study aims to highlight the potential of cochlear implants and emerging therapies in managing sensorineural hearing loss by improving access to the inner ear. The study is conducted through a review of relevant literature and research articles in the field of cochlear implants and emerging therapies for hearing loss. It outlines how advancements in cochlear implant technologies, electrodes, and surgical techniques can facilitate the delivery of therapies to the inner ear, potentially revolutionizing the treatment of sensorineural hearing loss. The study underscores the potential of cochlear implants and emerging therapies in revolutionizing the treatment landscape for sensorineural hearing loss, emphasizing the feasibility of curing this condition by leveraging technological advancements. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=therapies%20for%20hearing%20loss%20management" title="therapies for hearing loss management">therapies for hearing loss management</a>, <a href="https://publications.waset.org/abstracts/search?q=future%20of%20CI%20as%20a%20cochlear%20delivery%20channel" title=" future of CI as a cochlear delivery channel"> future of CI as a cochlear delivery channel</a>, <a href="https://publications.waset.org/abstracts/search?q=regenerative" title=" regenerative"> regenerative</a>, <a href="https://publications.waset.org/abstracts/search?q=genetic%20and%20pharmacotherapeutic%20management%20of%20hearing%20loss" title=" genetic and pharmacotherapeutic management of hearing loss"> genetic and pharmacotherapeutic management of hearing loss</a> </p> <a href="https://publications.waset.org/abstracts/185948/cochlear-implants-and-the-emerging-therapies-for-managing-hearing-loss" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/185948.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">48</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3405</span> Use of Alternative and Complementary Therapies in Patients with Chronic Pain in a Medical Institution in Medellin, Colombia, 2014</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Lina%20Mar%C3%ADa%20Mart%C3%ADnez%20S%C3%A1nchez">Lina María Martínez Sánchez</a>, <a href="https://publications.waset.org/abstracts/search?q=Juliana%20Molina%20Valencia"> Juliana Molina Valencia</a>, <a href="https://publications.waset.org/abstracts/search?q=Esteban%20Vallejo%20Agudelo"> Esteban Vallejo Agudelo</a>, <a href="https://publications.waset.org/abstracts/search?q=Daniel%20Gallego%20Gonz%C3%A1lez"> Daniel Gallego González</a>, <a href="https://publications.waset.org/abstracts/search?q=Mar%C3%ADa%20Isabel%20P%C3%A9rez%20Palacio"> María Isabel Pérez Palacio</a>, <a href="https://publications.waset.org/abstracts/search?q=Juan%20Ricardo%20Gaviria%20Garc%C3%ADa"> Juan Ricardo Gaviria García</a>, <a href="https://publications.waset.org/abstracts/search?q=Mar%C3%ADa%20De%20Los%20%C3%81ngeles%20Rodr%C3%ADguez%20G%C3%A1zquez"> María De Los Ángeles Rodríguez Gázquez</a>, <a href="https://publications.waset.org/abstracts/search?q=Gloria%20In%C3%A9s%20Mart%C3%ADnez%20Dom%C3%ADnguez"> Gloria Inés Martínez Domínguez</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Alternative and complementary therapies constitute a vast and complex combination of interventions, philosophies, approaches, and therapies that acquire a holistic healthcare point of view, becoming an alternative for the treatment of patients with chronic pain. Objective: determine the characteristics of the use of alternative and complementary therapies in patients with chronic pain who consulted in a medical institution. Methodology: cross-sectional and descriptive study, with a population of patients that assisted to the outpatient consultation and met the eligibility criteria. Sampling was not conducted. A form was used for the collection of demographic and clinical variables and the Holistic Complementary and Alternative Medicine Questionnaire (HCAMQ) was validated. The analysis and processing of information was carried out using the SPSS program vr.19. Results: 220 people with chronic pain were included. The average age was 54.7±16.2 years, 78.2% were women, and 75.5% belonged to the socioeconomic strata 1 to 3. Musculoskeletal pain (77.7%), migraine (15%) and neuralgia (9.1%) were the most frequently types of chronic pain. 33.6% of participants have used some kind of alternative and complementary therapy; the most frequent were: homeopathy (14.5%), phytotherapy (12.7%), and acupuncture (11.4%). The total average HCAMQ score for the study group was 30.2±7.0 points, which shows a moderate attitude toward the use of complementary and alternative medicine. The highest scores according to the type of pain were: neuralgia (32.4±5.8), musculoskeletal pain (30.5±6.7), fibromyalgia (29.6±7.3) and migraine (28.5±8.8). The reliability of the HCAMQ was acceptable (Cronbach's α: 0.6). Conclusion: it was noted that the types of chronic pain and the clinical or therapeutic management of patients correspond to the data available in current literature. Despite the moderate attitude toward the use of these alternative and complementary therapies, one of every three patients uses them. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=chronic%20pain" title="chronic pain">chronic pain</a>, <a href="https://publications.waset.org/abstracts/search?q=complementary%20therapies" title=" complementary therapies"> complementary therapies</a>, <a href="https://publications.waset.org/abstracts/search?q=homeopathy" title=" homeopathy"> homeopathy</a>, <a href="https://publications.waset.org/abstracts/search?q=acupuncture%20analgesia" title=" acupuncture analgesia"> acupuncture analgesia</a> </p> <a href="https://publications.waset.org/abstracts/41720/use-of-alternative-and-complementary-therapies-in-patients-with-chronic-pain-in-a-medical-institution-in-medellin-colombia-2014" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/41720.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">515</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3404</span> Cardiopulmonary Disease in Bipolar Disorder Patient with History of SJS: Evidence Based Case Report</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Zuhrotun%20Ulya">Zuhrotun Ulya</a>, <a href="https://publications.waset.org/abstracts/search?q=Muchammad%20Syamsulhadi"> Muchammad Syamsulhadi</a>, <a href="https://publications.waset.org/abstracts/search?q=Debree%20Septiawan"> Debree Septiawan</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Patients with bipolar disorder are three times more likely to suffer cardiovascular disorders than the general population, which will influence their level of morbidity and rate of mortality. Bipolar disorder also affects the pulmonary system. The choice of long term-monotherapy and other combinative therapies have clinical impacts on patients. This study investigates the case of a woman who has been suffering from bipolar disorder for 16 years, and who has a history of Steven Johnson Syndrome. At present she is suffering also from cardiovascular and pulmonary disorder. An analysis of the results of this study suggests that there is a relationship between cardiovascular disorder, drug therapies, Steven Johnson Syndrome and mood stabilizer obtained from the PubMed, Cochrane, Medline, and ProQuest (publications between 2005 and 2015). Combination therapy with mood stabilizer is recommended for patients who do not have side effect histories from these drugs. The replacement drugs and combinations may be applied, especially for those with bipolar disorders, and the combination between atypical antipsychotic groups and mood stabilizers is often made. Clinicians, however, should be careful with the patients’ physical and metabolic changes, especially those who have experienced long-term therapy and who showed a history of Steven Johnson Syndrome (for which clinicians probably prescribed one type of medicine). <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cardiopulmonary%20disease" title="cardiopulmonary disease">cardiopulmonary disease</a>, <a href="https://publications.waset.org/abstracts/search?q=bipolar%20disorder" title=" bipolar disorder"> bipolar disorder</a>, <a href="https://publications.waset.org/abstracts/search?q=SJS" title=" SJS"> SJS</a>, <a href="https://publications.waset.org/abstracts/search?q=therapy" title=" therapy"> therapy</a> </p> <a href="https://publications.waset.org/abstracts/48864/cardiopulmonary-disease-in-bipolar-disorder-patient-with-history-of-sjs-evidence-based-case-report" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/48864.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">430</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3403</span> Combination Therapies Targeting Apoptosis Pathways in Pediatric Acute Myeloid Leukemia (AML)</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ahlam%20Ali">Ahlam Ali</a>, <a href="https://publications.waset.org/abstracts/search?q=Katrina%20Lappin"> Katrina Lappin</a>, <a href="https://publications.waset.org/abstracts/search?q=Jaine%20Blayney"> Jaine Blayney</a>, <a href="https://publications.waset.org/abstracts/search?q=Ken%20Mills"> Ken Mills</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Leukaemia is the most frequently (30%) occurring type of paediatric cancer. Of these, approximately 80% are acute lymphoblastic leukaemia (ALL) with acute myeloid leukaemia (AML) cases making up the remaining 20% alongside other leukaemias. Unfortunately, children with AML do not have promising prognosis with only 60% surviving 5 years or longer. It has been highlighted recently the need for age-specific therapies for AML patients, with paediatric AML cases having a different mutational landscape compared with AML diagnosed in adult patients. Drug Repurposing is a recognized strategy in drug discovery and development where an already approved drug is used for diseases other than originally indicated. We aim to identify novel combination therapies with the promise of providing alternative more effective and less toxic induction therapy options. Our in-silico analysis highlighted ‘cell death and survival’ as an aberrant, potentially targetable pathway in paediatric AML patients. On this basis, 83 apoptotic inducing compounds were screened. A preliminary single agent screen was also performed to eliminate potentially toxic chemicals, then drugs were constructed into a pooled library with 10 drugs per well over 160 wells, with 45 possible pairs and 120 triples in each well. Seven cell lines were used during this study to represent the clonality of AML in paediatric patients (Kasumi-1, CMK, CMS, MV11-14, PL21, THP1, MOLM-13). Cytotoxicity was assessed up to 72 hours using CellTox™ Green reagent. Fluorescence readings were normalized to a DMSO control. Z-Score was assigned to each well based on the mean and standard deviation of all the data. Combinations with a Z-Score <2 were eliminated and the remaining wells were taken forward for further analysis. A well was considered ‘successful’ if each drug individually demonstrated a Z-Score <2, while the combination exhibited a Z-Score >2. Each of the ten compounds in one well (155) had minimal or no effect as single agents on cell viability however, a combination of two or more of the compounds resulted in a substantial increase in cell death, therefore the ten compounds were de-convoluted to identify a possible synergistic pair/triple combinations. The screen identified two possible ‘novel’ drug pairing, with BCL2 inhibitor ABT-737, combined with either a CDK inhibitor Purvalanol A, or AKT/ PI3K inhibitor LY294002. (ABT-737- 100 nM+ Purvalanol A- 1 µM) (ABT-737- 100 nM+ LY294002- 2 µM). Three possible triple combinations were identified (LY2409881+Akti-1/2+Purvalanol A, SU9516+Akti-1/2+Purvalanol A, and ABT-737+LY2409881+Purvalanol A), which will be taken forward for examining their efficacy at varying concentrations and dosing schedules, across multiple paediatric AML cell lines for optimisation of maximum synergy. We believe that our combination screening approach has potential for future use with a larger cohort of drugs including FDA approved compounds and patient material. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=AML" title="AML">AML</a>, <a href="https://publications.waset.org/abstracts/search?q=drug%20repurposing" title=" drug repurposing"> drug repurposing</a>, <a href="https://publications.waset.org/abstracts/search?q=ABT-737" title=" ABT-737"> ABT-737</a>, <a href="https://publications.waset.org/abstracts/search?q=apoptosis" title=" apoptosis"> apoptosis</a> </p> <a href="https://publications.waset.org/abstracts/141266/combination-therapies-targeting-apoptosis-pathways-in-pediatric-acute-myeloid-leukemia-aml" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/141266.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">203</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3402</span> Nutraceutical Potential of Mushroom Bioactive Metabolites and Their Food Functionality</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Jackson%20Ishara">Jackson Ishara</a>, <a href="https://publications.waset.org/abstracts/search?q=Ariel%20Buzera"> Ariel Buzera</a>, <a href="https://publications.waset.org/abstracts/search?q=Gustave%20N.%20Mushagalusa"> Gustave N. Mushagalusa</a>, <a href="https://publications.waset.org/abstracts/search?q=Ahmed%20R.%20A.%20Hammam"> Ahmed R. A. Hammam</a>, <a href="https://publications.waset.org/abstracts/search?q=Judith%20Munga"> Judith Munga</a>, <a href="https://publications.waset.org/abstracts/search?q=Paul%20Karanja"> Paul Karanja</a>, <a href="https://publications.waset.org/abstracts/search?q=John%20Kinyuru"> John Kinyuru</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Numerous mushroom bioactive metabolites, including polysaccharides, eritadenine, lignin, chitosan, mevinolin, and astrakurkurone have been studied in life-threatening conditions and diseases such as diabetes, cardiovascular, hypertension, cancer, DNA damage, hypercholesterolemia, and obesity attempting to identify natural therapies. These bioactive metabolites have shown potential as antiviral and immune system strengthener natural agents through diverse cellular and physiological pathways modulation with no toxicity evidence, widely available, and affordable. In light of the emerging literature, this paper compiles the most recent information describing the molecular mechanisms that underlie the nutraceutical potentials of these mushroom metabolites suggesting their effectiveness if combined with existing drug therapies. The findings raise hope that these mushroom bioactive metabolites may be utilized as natural therapies considering their therapeutic potential while anticipating further research designing clinical trials and developing new drug therapies while encouraging their consumption as a natural adjuvant in preventing and controlling life-threatening conditions and diseases. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bioactive%20metabolites" title="bioactive metabolites">bioactive metabolites</a>, <a href="https://publications.waset.org/abstracts/search?q=food%20functionality" title=" food functionality"> food functionality</a>, <a href="https://publications.waset.org/abstracts/search?q=health-threatening%20conditions" title=" health-threatening conditions"> health-threatening conditions</a>, <a href="https://publications.waset.org/abstracts/search?q=mushrooms" title=" mushrooms"> mushrooms</a>, <a href="https://publications.waset.org/abstracts/search?q=nutraceutical" title=" nutraceutical"> nutraceutical</a> </p> <a href="https://publications.waset.org/abstracts/151778/nutraceutical-potential-of-mushroom-bioactive-metabolites-and-their-food-functionality" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/151778.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">103</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3401</span> Multidrug Therapies For HIV: Hybrid On-Off, Hysteresis On-Off Control and Simple STI</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Magno%20Enrique%20Mendoza%20Meza">Magno Enrique Mendoza Meza</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This paper deals with the comparison of three control techniques: the hysteresis on-off control (HyOOC), the hybrid on-off control (HOOC) and the simple Structured Treatment Interruptions (sSTI). These techniques are applied to the mathematical model developed by Kirschner and Webb. To compare these techniques we use a cost functional that minimize the wild-type virus population and the mutant virus population, but the main objective is to minimize the systemic cost of treatment and maximize levels of healthy CD4+ T cells. HyOOC, HOOC, and sSTI are applied to the drug therapies using a reverse transcriptase and protease inhibitors; simulations show that these controls maintain the uninfected cells in a small, bounded neighborhood of a pre-specified level. The controller HyOOC and HOOC are designed by appropriate choice of virtual equilibrium points. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=virus%20dynamics" title="virus dynamics">virus dynamics</a>, <a href="https://publications.waset.org/abstracts/search?q=on-off%20control" title=" on-off control"> on-off control</a>, <a href="https://publications.waset.org/abstracts/search?q=hysteresis" title=" hysteresis"> hysteresis</a>, <a href="https://publications.waset.org/abstracts/search?q=multi-drug%20therapies" title=" multi-drug therapies"> multi-drug therapies</a> </p> <a href="https://publications.waset.org/abstracts/31489/multidrug-therapies-for-hiv-hybrid-on-off-hysteresis-on-off-control-and-simple-sti" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/31489.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">394</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3400</span> The Effect of Expressive Therapies on Children and Youth Impacted by Refugee Trauma: A Meta-Analysis</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Brian%20Kristopher%20Cambra">Brian Kristopher Cambra</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Millions of displaced families are seeking refuge in countries that are not their own due to war, violence, persecution, political unrest, and natural disasters. This global crisis is forcing researchers and practitioners to consider how refugees are coping with the trauma associated with their migration process. Effective therapeutic approaches are needed in a global effort to address the traumatic impact of forced migration. This meta-analytical study investigates the effectiveness of expressive therapeutic modalities, including play, art, music, sandplay, theatre, and writing therapies, in helping children and adolescents cope with refugee trauma. Seventeen pre-post and between-group comparison studies were analyzed using a random-effects model. The combined effect size for pre-post comparisons was medium (g = 0.58), whereas the combined effect size for between-group comparisons was small (g = 0.32). Overall, art therapy was found to be most effective in treating stress symptoms. Heterogeneity tests, however, suggest effect sizes cannot be interpreted as meaningful due to substantial variance. Nevertheless, findings of this meta-analysis indicate that expressive therapies may be among beneficial modalities to integrate with other trauma-informed approaches. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=expressive%20therapies" title="expressive therapies">expressive therapies</a>, <a href="https://publications.waset.org/abstracts/search?q=forced%20migration" title=" forced migration"> forced migration</a>, <a href="https://publications.waset.org/abstracts/search?q=meta-analysis" title=" meta-analysis"> meta-analysis</a>, <a href="https://publications.waset.org/abstracts/search?q=refugees" title=" refugees"> refugees</a>, <a href="https://publications.waset.org/abstracts/search?q=trauma" title=" trauma"> trauma</a> </p> <a href="https://publications.waset.org/abstracts/132384/the-effect-of-expressive-therapies-on-children-and-youth-impacted-by-refugee-trauma-a-meta-analysis" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/132384.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">147</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3399</span> Ozone Therapy and Pulsed Electromagnetic Fields Interplay in Controlling Tumor Growth, Symptom and Pain Management: A Case Report </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=J.%20F.%20Pollo%20Gaspary">J. F. Pollo Gaspary</a>, <a href="https://publications.waset.org/abstracts/search?q=F.%20Peron%20Gaspary"> F. Peron Gaspary</a>, <a href="https://publications.waset.org/abstracts/search?q=E.%20M.%20Sim%C3%A3o"> E. M. Simão</a>, <a href="https://publications.waset.org/abstracts/search?q=R.%20Concatto%20Beltrame"> R. Concatto Beltrame</a>, <a href="https://publications.waset.org/abstracts/search?q=G.%20Orengo%20de%20Oliveira"> G. Orengo de Oliveira</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20S.%20Ristow%20Ferreira"> M. S. Ristow Ferreira</a>, <a href="https://publications.waset.org/abstracts/search?q=F.%20Sartori%20Thies"> F. Sartori Thies</a>, <a href="https://publications.waset.org/abstracts/search?q=I.%20F.%20Minello"> I. F. Minello</a>, <a href="https://publications.waset.org/abstracts/search?q=F.%20dos%20Santos%20de%20Oliveira"> F. dos Santos de Oliveira</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: The immune system has evolved several mechanisms to protect the host against cancer, and it has now been suggested that the expansion of its functions may prevent tumor growth and control the symptoms of cancer patients. Two techniques, ozone therapy and pulsed electromagnetic fields (PEMF), are independently associated with an increase in the immune system functions and they maybe help palliative care of patients in these conditions. Case Report: A patient with rectal adenocarcinoma with metastases decides to interrupt the clinical chemotherapy protocol due to refractoriness and side effects. As a palliative care alternative treatment it is suggested to the patient the use of ozone therapy associated with PEMF techniques. Results: The patient reports an improvement in well-being, in autonomy and in pain control. Imaging tests confirm a pause in tumor growth despite more than 60 days without using classic treatment. These results associated with palliative care alternative treatment stimulate the return to the chemotherapy protocol. Discussion: This case illustrates that these two techniques can contribute to the control of tumor growth and refractory symptoms, such as pain, probably by enhancing the immune system. Conclusions: The potential use of the combination of these two therapies, ozone therapy and PEMF therapy, can contribute to palliation of cancer patients, alone or in combination with pharmacological therapies. The conduct of future investigations on this paradigm can elucidate how much these techniques contribute to the survival and well-being of these patients. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cancer" title="cancer">cancer</a>, <a href="https://publications.waset.org/abstracts/search?q=complementary%20and%20alternative%20medicine" title=" complementary and alternative medicine "> complementary and alternative medicine </a>, <a href="https://publications.waset.org/abstracts/search?q=ozone%20therapy" title=" ozone therapy"> ozone therapy</a>, <a href="https://publications.waset.org/abstracts/search?q=palliative%20care" title=" palliative care"> palliative care</a>, <a href="https://publications.waset.org/abstracts/search?q=PEMF%20therapy" title=" PEMF therapy"> PEMF therapy</a> </p> <a href="https://publications.waset.org/abstracts/129242/ozone-therapy-and-pulsed-electromagnetic-fields-interplay-in-controlling-tumor-growth-symptom-and-pain-management-a-case-report" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/129242.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">155</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3398</span> Cell-Based and Exosome Treatments for Hair Restoration</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Armin%20Khaghani%20Boroujeni">Armin Khaghani Boroujeni</a>, <a href="https://publications.waset.org/abstracts/search?q=Leila%20Dehghani"> Leila Dehghani</a>, <a href="https://publications.waset.org/abstracts/search?q=Parham%20Talebi%20Boroujeni"> Parham Talebi Boroujeni</a>, <a href="https://publications.waset.org/abstracts/search?q=Sahar%20Rostamian"> Sahar Rostamian</a>, <a href="https://publications.waset.org/abstracts/search?q=Ali%20Asilian"> Ali Asilian</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Hair loss is a common complaint observed in both genders. Androgenetic alopecia is known pattern for hair loss. To assess new regenerative strategies (PRP, A-SC-BT, conditioned media, exosome-based treatments) compared to conventional therapies for hair loss or hair regeneration, an updated review was undertaken. To address this issue, we carried out this systematic review to comprehensively evaluate the efficacy of cell-based therapies on hair loss. Methods: The available online databases, including ISI Web of Science, Scopus, and PubMed, were searched systematically up to February 2022. The quality assessment of included studies was done using the Cochrane Collaboration's tool. Results: As a result, a total of 90 studies involving 2345 participants were included in the present study. The enrolled studies were conducted between 2010 and 2022. The subjects’ mean age ranged from 19 to 55.11 years old. Approaches using platelet rich plasma (PRP) provide a beneficial impact on hair regrowth. However, other cell-based therapies, including stem cell transplant, stem cell-derived conditioned medium, and stem cell-derived exosomes, revealed conflicting evidence. Conclusion: However, cell-based therapies for hair loss are still in their infancy, and more robust clinical studies are needed to better evaluate their mechanisms of action, efficacy, safety, benefits, and limitations. In this review, we provide the resources to the latest clinical studies and a more detailed description of the latest clinical studies concerning cell-based therapies in hair loss. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cell-based%20therapy" title="cell-based therapy">cell-based therapy</a>, <a href="https://publications.waset.org/abstracts/search?q=exosome" title=" exosome"> exosome</a>, <a href="https://publications.waset.org/abstracts/search?q=hair%20restoration" title=" hair restoration"> hair restoration</a>, <a href="https://publications.waset.org/abstracts/search?q=systematic%20review" title=" systematic review"> systematic review</a> </p> <a href="https://publications.waset.org/abstracts/147922/cell-based-and-exosome-treatments-for-hair-restoration" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/147922.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">75</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3397</span> An Empirical Diagnosis of the Maladies and Therapies of Budgeting in Nigeria</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ben-Caleb%20Egbide">Ben-Caleb Egbide</a>, <a href="https://publications.waset.org/abstracts/search?q=Omolehinwa%20O.%20Eddy"> Omolehinwa O. Eddy</a>, <a href="https://publications.waset.org/abstracts/search?q=Adeyemi%20S.%20Keyinde"> Adeyemi S. Keyinde</a>, <a href="https://publications.waset.org/abstracts/search?q=Eriabie%20Sylvester"> Eriabie Sylvester</a>, <a href="https://publications.waset.org/abstracts/search?q=Ojeka%20Stephen"> Ojeka Stephen</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The national budget remains an integral part of the developmental plan of the economy of any country. The budget reflects the fundamental values underlying the government’s economic policies and objectives and whose execution is expected to realize national/public desires. In Nigeria, over three decades budget had failed to deliver the desired benefits, suggesting the existence of infractions, which are yet to be empirically ascertained. This paper attempts a diagnosis of the infractions peculiar to Nigeria budgetary system and their suggested panacea. Data were collected through the administration of questionnaire to a cross section of organizations/institutions representing government agencies and the general public. Mann-Whitney U test was employed to gauge the consistency in perception of the two groups. The result revealed that budget indiscipline, official corruption, allocative inefficiency and poor budget governance are the most influential infractions of budgeting in Nigeria. Consequently, it was suggested that budget transparency, target budgeting, zero tolerance on corruption and budget discipline are the most cogent therapies to the malfunctioning in Nigerian budgetary system. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=budgeting" title="budgeting">budgeting</a>, <a href="https://publications.waset.org/abstracts/search?q=budget%20maladies" title=" budget maladies"> budget maladies</a>, <a href="https://publications.waset.org/abstracts/search?q=budget%20therapies" title=" budget therapies"> budget therapies</a>, <a href="https://publications.waset.org/abstracts/search?q=Nigeria" title=" Nigeria "> Nigeria </a> </p> <a href="https://publications.waset.org/abstracts/78327/an-empirical-diagnosis-of-the-maladies-and-therapies-of-budgeting-in-nigeria" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/78327.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">291</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3396</span> The Use of Stochastic Gradient Boosting Method for Multi-Model Combination of Rainfall-Runoff Models</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Phanida%20Phukoetphim">Phanida Phukoetphim</a>, <a href="https://publications.waset.org/abstracts/search?q=Asaad%20Y.%20Shamseldin"> Asaad Y. Shamseldin</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In this study, the novel Stochastic Gradient Boosting (SGB) combination method is addressed for producing daily river flows from four different rain-runoff models of Ohinemuri catchment, New Zealand. The selected rainfall-runoff models are two empirical black-box models: linear perturbation model and linear varying gain factor model, two conceptual models: soil moisture accounting and routing model and Nedbør-Afrstrømnings model. In this study, the simple average combination method and the weighted average combination method were used as a benchmark for comparing the results of the novel SGB combination method. The models and combination results are evaluated using statistical and graphical criteria. Overall results of this study show that the use of combination technique can certainly improve the simulated river flows of four selected models for Ohinemuri catchment, New Zealand. The results also indicate that the novel SGB combination method is capable of accurate prediction when used in a combination method of the simulated river flows in New Zealand. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=multi-model%20combination" title="multi-model combination">multi-model combination</a>, <a href="https://publications.waset.org/abstracts/search?q=rainfall-runoff%20modeling" title=" rainfall-runoff modeling"> rainfall-runoff modeling</a>, <a href="https://publications.waset.org/abstracts/search?q=stochastic%20gradient%20boosting" title=" stochastic gradient boosting"> stochastic gradient boosting</a>, <a href="https://publications.waset.org/abstracts/search?q=bioinformatics" title=" bioinformatics"> bioinformatics</a> </p> <a href="https://publications.waset.org/abstracts/3455/the-use-of-stochastic-gradient-boosting-method-for-multi-model-combination-of-rainfall-runoff-models" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/3455.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">339</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3395</span> Skin Care through Ayurveda</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=K.%20L.%20Virupaksha%20Gupta">K. L. Virupaksha Gupta </a> </p> <p class="card-text"><strong>Abstract:</strong></p> Ayurveda offers a holistic outlook regarding skin care. Most Initial step in Ayurveda is to identify the skin type and care accordingly which is highly personalized. Though dermatologically there are various skin type classifications such Baumann skin types (based on 4 parameters i) Oily Vs Dry ii) Sensitive Vs Resistant iii) Pigmented Vs Non-Pigmented iv) Wrinkled Vs Tight (Unwrinkled) etc but Skin typing in Ayurveda is mainly determined by the prakriti (constitution) of the individual as well as the status of Doshas (Humors) which are basically of 3 types – i.e Vata Pitta and Kapha,. Difference between them is mainly attributed to the qualities of each dosha (humor). All the above said skin types can be incorporated under these three types. The skin care modalities in each of the constitution vary greatly. Skin of an individual of Vata constitution would be lustreless, having rough texture and cracks due to dryness and thus should be given warm and unctuous therapies and oil massage for lubrication and natural moisturizers for hydration. Skin of an individual of Pitta constitution would look more vascular (pinkish), delicate and sensitive with a fair complexion, unctuous and tendency for wrinkles and greying of hair at an early age and hence should be given cooling and nurturing therapies and should avoid tanning treatments. Skin of an individual of kapha constitution will have oily skin, they are delicate and look beautiful and radiant and hence these individuals would require therapies to mainly combat oily skin. Hence, the skin typing and skin care in Ayurveda is highly rational and scientific. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ayurveda" title="Ayurveda">Ayurveda</a>, <a href="https://publications.waset.org/abstracts/search?q=dermatology" title=" dermatology"> dermatology</a>, <a href="https://publications.waset.org/abstracts/search?q=Dosha" title=" Dosha"> Dosha</a>, <a href="https://publications.waset.org/abstracts/search?q=skin%20types" title=" skin types"> skin types</a> </p> <a href="https://publications.waset.org/abstracts/19790/skin-care-through-ayurveda" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/19790.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">407</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3394</span> Effects of the Treatment by Polypill Combinations vs Identical Monopill Therapies in Patients with Cardiovascular Comorbid Diseases</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Denys%20Sebov">Denys Sebov</a>, <a href="https://publications.waset.org/abstracts/search?q=Viktoriia%20Korotaieva"> Viktoriia Korotaieva</a>, <a href="https://publications.waset.org/abstracts/search?q=Kateryna%20Markina"> Kateryna Markina</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The clinical advantage of the multipill combination drugs administration (polypill-strategy) over single-component drugs (monopill-strategy) has been established in patients with comorbid arterial hypertension, heart failure, chronic coronary syndrome, diabetes. It was found that polypill-strategy provides better treatment adherence in 33.4% of the patients. It was proven a significant decrease in systolic and diastolic blood pressure, as well as a decrease in dispersion index due to the stability of the blood pressure profile in patients with the polypill-strategy treatment. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=polypill" title="polypill">polypill</a>, <a href="https://publications.waset.org/abstracts/search?q=artetial%20hypertension" title=" artetial hypertension"> artetial hypertension</a>, <a href="https://publications.waset.org/abstracts/search?q=cardiovascular%20disease" title=" cardiovascular disease"> cardiovascular disease</a>, <a href="https://publications.waset.org/abstracts/search?q=compliance" title=" compliance"> compliance</a> </p> <a href="https://publications.waset.org/abstracts/185388/effects-of-the-treatment-by-polypill-combinations-vs-identical-monopill-therapies-in-patients-with-cardiovascular-comorbid-diseases" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/185388.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">61</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3393</span> Biomedicine, Suffering, and Sacrifice: Myths and Prototypes in Cell and Gene Therapies</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Edison%20Bicudo">Edison Bicudo</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Cell and gene therapies (CGTs) result from the intense manipulation of cells or the use of techniques such as gene editing. They have been increasingly used to tackle rare diseases or conditions of genetic origin, such as cancer. One might expect such a complex scientific field to be dominated by scientific findings and evidence-based explanations. However, people engaged in scientific argumentation also mobilize a range of cognitive operations of which they are not fully aware, in addition to drawing on widely available oral traditions. This paper analyses how experts discussing the potentialities and challenges of CGTs have recourse to a particular kind of prototypical myth. This sociology study, conducted at the University of Sussex (UK), involved interviews with scientists, regulators, and entrepreneurs involved in the development or governance of CGTs. It was observed that these professionals, when voicing their views, sometimes have recourse to narratives where CGTs appear as promising tools for alleviating or curing diseases. This is said to involve much personal, scientific, and financial sacrifice. In his study of traditional narratives, Hogan identified three prototypes: the romantic narrative, moved by the ideal of romantic union; the heroic narrative, moved by the desire for political power; and the sacrificial narrative, where the ideal is plenty, well-being, and health. It is argued here that discourses around CGTs often involve some narratives – or myths – that have a sacrificial nature. In this sense, the development of innovative therapies is depicted as a huge sacrificial endeavor involving biomedical scientists, biotech and pharma companies, and decision-makers. These sacrificial accounts draw on oral traditions and benefit from an emotional intensification that can be easily achieved in stories of serious diseases and physical suffering. Furthermore, these accounts draw on metaphorical understandings where diseases and vectors of diseases are considered enemies or invaders while therapies are framed as shields or protections. In this way, this paper aims to unravel the cognitive underpinnings of contemporary science – and, more specifically, biomedicine – revealing how myths, prototypes, and metaphors are highly operative even when complex reasoning is at stake. At the same time, this paper demonstrates how such hidden cognitive operations underpin the construction of powerful ideological discourses aimed at defending certain ways of developing, disseminating, and governing technologies and therapies. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cell%20and%20gene%20therapies" title="cell and gene therapies">cell and gene therapies</a>, <a href="https://publications.waset.org/abstracts/search?q=myths" title=" myths"> myths</a>, <a href="https://publications.waset.org/abstracts/search?q=prototypes" title=" prototypes"> prototypes</a>, <a href="https://publications.waset.org/abstracts/search?q=metaphors" title=" metaphors"> metaphors</a> </p> <a href="https://publications.waset.org/abstracts/192072/biomedicine-suffering-and-sacrifice-myths-and-prototypes-in-cell-and-gene-therapies" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/192072.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">17</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3392</span> Azaridachta Indica (Neem) Seed Oil Effect in Experimental Arthritis – Biochemical Parameters Assessment</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sasan%20Khademnematolahi">Sasan Khademnematolahi</a>, <a href="https://publications.waset.org/abstracts/search?q=Kevine%20Kamga%20Silihe"> Kevine Kamga Silihe</a>, <a href="https://publications.waset.org/abstracts/search?q=Katar%C3%ADna%20Pru%C5%BEinsk%C3%A1"> Katarína Pružinská</a>, <a href="https://publications.waset.org/abstracts/search?q=Martina%20Chrastina"> Martina Chrastina</a>, <a href="https://publications.waset.org/abstracts/search?q=Elisabeth%20Louise%20Ndjengue%20Mindang"> Elisabeth Louise Ndjengue Mindang</a>, <a href="https://publications.waset.org/abstracts/search?q=Franti%C5%A1ek%20Dr%C3%A1fi"> František Dráfi</a>, <a href="https://publications.waset.org/abstracts/search?q=Katar%C3%ADna%20Bauerov%C3%A1"> Katarína Bauerová</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: In ethnomedicine, plant parts and compounds are traditionally utilized to treat many disorders. Azadirachta indica, known as Neem, has been traditionally used in medicinal practices. Neem has various pharmaceutical activities, such as antioxidant and anti-inflammatory, due to the content of bioactive compounds like nimbolide, azadirachtin, and gedunin.Through its effect on pathological inflammatory processes, supplementation with it could alleviate the symptoms of rheumatoid arthritis (RA). Methods: This research aimed to assess Neem seed oil's impact on rats with adjuvant arthritis. Three doses in monotherapy and two in combination with methotrexate (MTX) have been studied and their effect was compared. Neem p.o. doses of 100, 200, and 300 mg/kg and MTX p.o. doses of 0.3 mg/kg were examined. After clinical parameters assessment, biochemical analysis was performed in plasma. Results: During the acute phase of the experimental arthritis (Day21), levels of MMP-9, MCP-1 and cytokines IL-1beta and IL-17A were measured. The positive results of inflammatory mediators evaluation in plasma encourage additional analysis also in related tissues to prove if Neem seed oil can be used as an adjuvant therapy for RA. Conclusion: In this study, the combination therapy of Neem with MTX was most effective from all therapies investigated. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=adjuvant" title="adjuvant">adjuvant</a>, <a href="https://publications.waset.org/abstracts/search?q=neem" title=" neem"> neem</a>, <a href="https://publications.waset.org/abstracts/search?q=methotrexate" title=" methotrexate"> methotrexate</a>, <a href="https://publications.waset.org/abstracts/search?q=arthritis" title=" arthritis"> arthritis</a> </p> <a href="https://publications.waset.org/abstracts/186176/azaridachta-indica-neem-seed-oil-effect-in-experimental-arthritis-biochemical-parameters-assessment" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/186176.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">46</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3391</span> Enhanced Anti-Inflammatory and Antioxidant Activities of Perna canaliculus Oil Extract and Low Molecular Weight Fucoidan from Undaria pinnatifida</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Belgheis%20Ebrahimi">Belgheis Ebrahimi</a>, <a href="https://publications.waset.org/abstracts/search?q=Jun%20Lu"> Jun Lu</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In recent years, there has been a growing recognition of the potential of marine-based functional foods and combination therapies in promoting a healthy lifestyle and exploring their effectiveness in preventing or treating diseases. The combination of marine bioactive compounds or extracts offers synergistic or enhancement effects through various mechanisms, including multi-target actions, improved bioavailability, enhanced bioactivity, and mitigation of potential adverse effects. Both the green-lipped mussel (GLM) and fucoidan derived from brown seaweed are rich in bioactivities. These two, mussel and fucoidan, have not been previously formulated together. This study aims to combine GLM oil from Perna canaliculus with low molecular weight fucoidan (LMWF) extracted from Undaria pinnatifida to investigate the unique mixture’s anti-inflammatory and antioxidant properties. The cytotoxicity of individual compounds and combinations was assessed using the MTT assay in (THP-1 and RAW264.7) cell lines. The anti-inflammatory activity of mussel-fucoidan was evaluated by treating LPS-stimulated human monocyte and macrophage (THP1-1) cells. Subsequently, the inflammatory cytokines released into the supernatant of these cell lines were quantified via ELISA. Antioxidant activity was determined by using the free radical scavenging assay (DPPH). DPPH assay demonstrated that the radical scavenging activity of the combinations, particularly at concentrations exceeding 1 mg/ml, showed a significantly higher percentage of inhibition when compared to the individual component. This suggests an enhancement effect when the two compounds are combined, leading to increased antioxidant activity. In terms of immunomodulatory activity, the individual compounds exhibited distinct behaviors. GLM oil displayed a higher ability to suppress the cytokine TNF- compared to LMWF. Interestingly, the LMWF fraction, when used individually, did not demonstrate TNF- suppression. However, when combined with GLM, the TNF- suppression (anti-inflammatory) activity of the combination was better than GLM or LWMF alone. This observation underscores the potential for enhancement interactions between the two components in terms of anti-inflammatory properties. This study revealed that each individual compound, LMWF, and GLM, possesses unique and notable bioactivity. The combination of these two individual compounds results in an enhancement effect, where the bioactivity of each is enhanced, creating a superior combination. This suggests that the combination of LMWF and GLM has the potential to offer a more potent and multifaceted therapeutic effect, particularly in the context of antioxidant and anti-inflammatory activities. These findings hold promise for the development of novel therapeutic interventions or supplements that harness the enhancement effects. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=combination" title="combination">combination</a>, <a href="https://publications.waset.org/abstracts/search?q=enhancement%20effect" title=" enhancement effect"> enhancement effect</a>, <a href="https://publications.waset.org/abstracts/search?q=perna%20canaliculus" title=" perna canaliculus"> perna canaliculus</a>, <a href="https://publications.waset.org/abstracts/search?q=undaria%20pinnatifida" title=" undaria pinnatifida"> undaria pinnatifida</a> </p> <a href="https://publications.waset.org/abstracts/174546/enhanced-anti-inflammatory-and-antioxidant-activities-of-perna-canaliculus-oil-extract-and-low-molecular-weight-fucoidan-from-undaria-pinnatifida" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/174546.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">81</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3390</span> Assessment of Barriers to the Clinical Adoption of Cell-Based Therapeutics</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=David%20Pettitt">David Pettitt</a>, <a href="https://publications.waset.org/abstracts/search?q=Benjamin%20Davies"> Benjamin Davies</a>, <a href="https://publications.waset.org/abstracts/search?q=Georg%20Holl%C3%A4nder"> Georg Holländer</a>, <a href="https://publications.waset.org/abstracts/search?q=David%20Brindley"> David Brindley</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Cellular based therapies, whose origins can be traced from the intertwined concepts of tissue engineering and regenerative medicine, have the potential to transform the current medical landscape and offer an approach to managing what were once considered untreatable diseases. However, despite a large increase in basic science activity in the cell therapy arena alongside a growing portfolio of cell therapy trials, the number of industry products available for widespread clinical use correlates poorly with such a magnitude of activity, with the number of cell-based therapeutics in mainstream use remaining comparatively low. This research serves to quantitatively assess the barriers to the clinical adoption of cell-based therapeutics through identification of unique barriers, specific challenges and opportunities facing the development and adoption of such therapies. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cell%20therapy" title="cell therapy">cell therapy</a>, <a href="https://publications.waset.org/abstracts/search?q=clinical%20adoption" title=" clinical adoption"> clinical adoption</a>, <a href="https://publications.waset.org/abstracts/search?q=commercialization" title=" commercialization"> commercialization</a>, <a href="https://publications.waset.org/abstracts/search?q=translation" title=" translation"> translation</a> </p> <a href="https://publications.waset.org/abstracts/43347/assessment-of-barriers-to-the-clinical-adoption-of-cell-based-therapeutics" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/43347.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">400</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3389</span> Medical versus Non-Medical Students' Opinions about Academic Stress Management Using Unconventional Therapies</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ramona-Niculina%20Jurcau">Ramona-Niculina Jurcau</a>, <a href="https://publications.waset.org/abstracts/search?q=Ioana-Marieta%20Jurcau"> Ioana-Marieta Jurcau</a>, <a href="https://publications.waset.org/abstracts/search?q=Dong%20Hun%20Kwak"> Dong Hun Kwak</a>, <a href="https://publications.waset.org/abstracts/search?q=Nicolae-Alexandru%20Colceriu"> Nicolae-Alexandru Colceriu</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Stress management (SM) is a topic of great academic interest and equally a task to accomplish. In addition, it is recognized the beneficial role of unconventional therapies (UCT) in stress modulation. Aims: The aim was to evaluate medical (MS) versus non-medical students’ (NMS) opinions about academic stress management (ASM) using UCT. Methods: MS (n=103, third year males and females) and NMS (n=112, males and females, from humanities faculties, different years of study), out of their academic program, voluntarily answered to a questionnaire concerning: a) Classification of the four most important academic stress factors; b) The extent to which their daily life influences academic stress; c) The most important SM methods they know; d) Which of these methods they are applying; e) the UCT they know or about which they have heard; f) Which of these they know to have stress modulation effects; g) Which of these UCT, participants are using or would like to use for modulating stress; and if participants use UTC for their own choose or following a specialist consultation in those therapies (SCT); h) If they heard about the following UCT and what opinion they have (using visual analogue scale) about their use (following CST) for the ASM: Phytotherapy (PT), apitherapy (AT), homeopathy (H), ayurvedic medicine (AM), traditional Chinese medicine (TCM), music therapy (MT), color therapy (CT), forest therapy (FT). Results: Among the four most important academic stress factors, for MS more than for NMS, are: busy schedule, large amount of information taught; high level of performance required, reduced time for relaxing. The most important methods for SM that MS and NMS know, hierarchically are: listen to music, meeting friends, playing sport, hiking, sleep, regularly breaks, seeing positive side, faith; of which, NMS more than MS, are partially applying to themselves. UCT about which MS and less NMS have heard, are phytotherapy, apitherapy, acupuncture, reiki. Of these UTC, participants know to have stress modulation effects: some plants, bee’s products and music; they use or would like to use for ASM (the majority without SCT) certain teas, honey and music. Most of MS and only some NMS heard about PT, AT, TCM, MT and much less about H, AM, CT, TT. NMS more than MS, would use these UCT, following CST. Conclusions: 1) Academic stress is similarly reflected in MS and NMS opinions. 2) MS and NMS apply similar but very few UCT for stress modulation. 3) Information that MS and NMS have about UCT and their ASM application is reduced. 4) It is remarkable that MS and especially NMS, are open to UCT use for ASM, following an SCT. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=academic%20stress" title="academic stress">academic stress</a>, <a href="https://publications.waset.org/abstracts/search?q=stress%20management" title=" stress management"> stress management</a>, <a href="https://publications.waset.org/abstracts/search?q=stress%20modulation" title=" stress modulation"> stress modulation</a>, <a href="https://publications.waset.org/abstracts/search?q=medical%20students" title=" medical students"> medical students</a>, <a href="https://publications.waset.org/abstracts/search?q=non-medical%20students" title=" non-medical students"> non-medical students</a>, <a href="https://publications.waset.org/abstracts/search?q=unconventional%20therapies" title=" unconventional therapies"> unconventional therapies</a> </p> <a href="https://publications.waset.org/abstracts/54768/medical-versus-non-medical-students-opinions-about-academic-stress-management-using-unconventional-therapies" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/54768.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">356</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3388</span> CICAP: Promising Wound Healing Gel from Bee Products and Medicinal Plants</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=La%C3%AFd%20Boukra%C3%A2">Laïd Boukraâ</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Complementary and Alternative Medicine is an inclusive term that describes treatments, therapies, and modalities that are not accepted as components of mainstream education or practice, but that are performed on patients by some practitioners. While these treatments and therapies often form part of post-graduate education, study and writing, they are generally viewed as alternatives or complementary to more universally accepted treatments. Ancient civilizations used bee products and medicinal plants, but modern civilization and ‘education’ have seriously lessened our natural instinctive ability and capability. Despite the fact that the modern Western establishment appears to like to relegate apitherapy and aromatherapy to the status of 'folklore' or 'old wives' tales', they contain a vast spread of pharmacologically-active ingredients and each one has its own unique combination and properties. They are classified in modern herbal medicine according to their spheres of action. Bee products and medicinal plants are well-known natural product for their healing properties and their increasing popularity recently as they are widely used in wound healing. Honey not only has antibacterial properties which can help as an antibacterial agent but also has chemical properties which may further help in the wound healing process. A formulation with honey as its main component was produced into a honey gel. This new formulation has enhanced texture and is more user friendly for usage as well. This new formulation would be better than other formulas as it is hundred percent consisting of natural products and has been made into a better formulation. In vitro assay, animal model study and clinical trials have shown the effectiveness of LEADERMAX for the treatment of diabetic foot, burns, leg ulcer and bed sores. This one hundred percent natural product could be the best alternative to conventional products for wound and burn management. The advantages of the formulation are: 100% natural, affordable, easy to use, strong power of absorption, dry surface on the wound making a film, will not stick to the wound bed; helps relieve wound pain, inflammation, edema and bruising while improving comfort. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bed%20sore%20bee%20products" title="bed sore bee products">bed sore bee products</a>, <a href="https://publications.waset.org/abstracts/search?q=burns" title=" burns"> burns</a>, <a href="https://publications.waset.org/abstracts/search?q=diabetic%20foot" title=" diabetic foot"> diabetic foot</a>, <a href="https://publications.waset.org/abstracts/search?q=medicinal%20plants" title=" medicinal plants"> medicinal plants</a>, <a href="https://publications.waset.org/abstracts/search?q=leg%20ulcer" title=" leg ulcer"> leg ulcer</a>, <a href="https://publications.waset.org/abstracts/search?q=wounds" title=" wounds"> wounds</a> </p> <a href="https://publications.waset.org/abstracts/41515/cicap-promising-wound-healing-gel-from-bee-products-and-medicinal-plants" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/41515.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">337</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3387</span> Current Concepts of Male Aesthetics: Facial Areas to Be Focused and Prioritized with Botulinum Toxin and Hyaluronic Acid Dermal Fillers Combination Therapies, Recommendations on Asian Patients </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sadhana%20Deshmukh">Sadhana Deshmukh</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Objective: Men represent only a fraction of the medical aesthetic practice. They are increasingly becoming more cosmetically-inclined. The primary objective is to harmonize facial proportion by prioritizing and focusing on forehead nose, cheek and chin complex. Introduction: Despite tremendous variability, diverse population of the Indian subcontinent, the male skull is unique in its overall larger size, and shape. Men tend to have a large forehead with prominent supraorbital ridges, wide glabella, square orbit, and a prominent protruding mandible. Men have increased skeletal muscle mass, with less facial subcutaneous fat. Facial aesthetics is evolving rapidly. Commonly published canons of facial proportions usually represent feminine standards and are not applicable to males. Strict adherence to these norms is therefore not necessary to obtain satisfying results in male patients. Materials and Methods: Male patients age group 30-60 years have been enrolled. Botulinum toxin and hyaluronic acid fillers were used to update consensus recommendations for facial rejuvenation using these two types of products alone and in combination. Results: There are specific recommendations by facial area, focusing on relaxing musculature, restoring volume, recontouring using toxin and dermal fillers alone and in combination. For upper face, though botulinum toxin remains the cornerstone of treatment, temples and forehead fillers are recommended for optimal results. In Mid face, these fillers are placed more laterally to maintain the masculine look. Botulinum toxin and fillers in combination can improve outcomes in the lower face. Chin augmentation remains the center point for lower face. Conclusions: Males are more likely to have shorter doctor visits, less likely to ask questions, have a lower attention to bodily changes. The physician must patiently gauge male patients’ aging and cosmetic goals. Clinicians can also benefit from ongoing guidance on products, tailoring treatments, treating multiple facial areas, and using combinations of products. An appreciation that rejuvenation is 3-dimensional process involving muscle control, volume restoration and recontouring helps. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=male%20aesthetics" title="male aesthetics">male aesthetics</a>, <a href="https://publications.waset.org/abstracts/search?q=botulinum%20toxin" title=" botulinum toxin"> botulinum toxin</a>, <a href="https://publications.waset.org/abstracts/search?q=hyaluronic%20acid%20dermal%20fillers" title=" hyaluronic acid dermal fillers"> hyaluronic acid dermal fillers</a>, <a href="https://publications.waset.org/abstracts/search?q=Asian%20patients" title=" Asian patients"> Asian patients</a> </p> <a href="https://publications.waset.org/abstracts/85863/current-concepts-of-male-aesthetics-facial-areas-to-be-focused-and-prioritized-with-botulinum-toxin-and-hyaluronic-acid-dermal-fillers-combination-therapies-recommendations-on-asian-patients" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/85863.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">157</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3386</span> Devotional Informant and Diagenetic Alterations, Influences of Facies and Fine Kaolinite Formation Migration on Sandstone’ Reservoir Quality, Sarir Formation, Sirt</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Faraj%20M.%20Elkhatri">Faraj M. Elkhatri</a>, <a href="https://publications.waset.org/abstracts/search?q=Hana%20Ellafi"> Hana Ellafi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In recent years, there has been a growing recognition of the potential of marine-based functional foods and combination therapies in promoting a healthy lifestyle and exploring their effectiveness in preventing or treating diseases. The combination of marine bioactive compounds or extracts offers synergistic or enhancement effects through various mechanisms, including multi-target actions, improved bioavailability, enhanced bioactivity, and mitigation of potential adverse effects. Both the green-lipped mussel (GLM) and fucoidan derived from brown seaweed are rich in bioactivities. These two, mussel and fucoidan, have not been previously formulated together. This study aims to combine GLM oil from Perna canaliculus with low molecular weight fucoidan (LMWF) extracted from Undaria pinnatifida to investigate the unique mixture’s anti-inflammatory and antioxidant properties. The cytotoxicity of individual compounds and combinations was assessed using the MTT assay in (THP-1 and RAW264.7) cell lines. The anti-inflammatory activity of mussel-fucoidan was evaluated by treating LPS-stimulated human monocyte and macrophage (THP1-1) cells. Subsequently, the inflammatory cytokines released into the supernatant of these cell lines were quantified via ELISA. Antioxidant activity was determined by using the free radical scavenging assay (DPPH). DPPH assay demonstrated that the radical scavenging activity of the combinations, particularly at concentrations exceeding 1 mg/ml, showed a significantly higher percentage of inhibition when compared to the individual component. This suggests an enhancement effect when the two compounds are combined, leading to increased antioxidant activity. In terms of immunomodulatory activity, the individual compounds exhibited distinct behaviors. GLM oil displayed a higher ability to suppress the cytokine TNF- compared to LMWF. Interestingly, the LMWF fraction, when used individually, did not demonstrate TNF- suppression. However, when combined with GLM, the TNF- suppression (anti-inflammatory) activity of the combination was better than GLM or LWMF alone. This observation underscores the potential for enhancement interactions between the two components in terms of anti-inflammatory properties. This study revealed that each individual compound, LMWF, and GLM, possesses unique and notable bioactivity. The combination of these two individual compounds results in an enhancement effect, where the bioactivity of each is enhanced, creating a superior combination. This suggests that the combination of LMWF and GLM has the potential to offer a more potent and multifaceted therapeutic effect, particularly in the context of antioxidant and anti-inflammatory activities. These findings hold promise for the development of novel therapeutic interventions or supplements that harness the enhancement effects. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=formation%20damage" title="formation damage">formation damage</a>, <a href="https://publications.waset.org/abstracts/search?q=porosity%20loses" title=" porosity loses"> porosity loses</a>, <a href="https://publications.waset.org/abstracts/search?q=pore%20throat" title=" pore throat"> pore throat</a>, <a href="https://publications.waset.org/abstracts/search?q=quartz%20cement" title=" quartz cement"> quartz cement</a> </p> <a href="https://publications.waset.org/abstracts/174594/devotional-informant-and-diagenetic-alterations-influences-of-facies-and-fine-kaolinite-formation-migration-on-sandstone-reservoir-quality-sarir-formation-sirt" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/174594.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">57</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3385</span> Evaluating Imitation Behavior of Children with Autism Spectrum Disorder Using Humanoid Robot NAO</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Masud%20Karim">Masud Karim</a>, <a href="https://publications.waset.org/abstracts/search?q=Md.%20Solaiman%20Mia"> Md. Solaiman Mia</a>, <a href="https://publications.waset.org/abstracts/search?q=Saifuddin%20Md.%20Tareeq"> Saifuddin Md. Tareeq</a>, <a href="https://publications.waset.org/abstracts/search?q=Md.%20Hasanuzzaman"> Md. Hasanuzzaman</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Autism Spectrum Disorder (ASD) is a neurodevelopment disorder. Such disorder is found in childhood life. Children with ASD have less capabilities in communication and social skills. Therapies are used to develop communication and social skills. Recently researchers have been trying to use robots in such therapies. In this paper, we have presented social skill learning test cases for children with ASD. Autism conditions are measured in 30 children in a special school. Among them, twelve children are selected who have equal ASD conditions. Then six children participated in training with humans, and another six children participated in training with robots. The learning session continued for one week and three hours each day. We have taken an assessment test before the learning sessions. After completing the learning sessions, we have taken another assessment test. We have found better performances from children who have participated in robotic sessions rather than the children who have participated in human sessions. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=children%20with%20ASD" title="children with ASD">children with ASD</a>, <a href="https://publications.waset.org/abstracts/search?q=NAO%20robot" title=" NAO robot"> NAO robot</a>, <a href="https://publications.waset.org/abstracts/search?q=human-robot%20interaction" title=" human-robot interaction"> human-robot interaction</a>, <a href="https://publications.waset.org/abstracts/search?q=social%20skills" title=" social skills"> social skills</a> </p> <a href="https://publications.waset.org/abstracts/163452/evaluating-imitation-behavior-of-children-with-autism-spectrum-disorder-using-humanoid-robot-nao" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/163452.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">88</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3384</span> Evaluation of Immunology of Asthma Chronic Obstructive</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Milad%20Gholizadeh">Milad Gholizadeh</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Asthma and chronic obstructive pulmonary disease (COPD) are very shared inflammatory diseases of the airlines. They togethercause airway tapering and are cumulative in occurrence throughout the world, imposing huge burdens on health care. It is currently recognized that some asthmatic inflammation is neutrophilic, controlled by the TH17 subset of helper T cells, and that some eosinophilic inflammation is controlled by type 2 innate lymphoid cells (ILC2 cells) temporary together with basophils. Patients who have plain asthma or are asthmatic patients who smoke with topographies of COPD-induced inflammation and might advantage from treatments targeting neutrophils, countingmacrolides, CXCR2 antagonists, phosphodiesterase 4 inhibitors, p38 mitogen-activating protein kinase inhibitors, and antibodies in contradiction of IL-1 and IL-17.Viral and bacterial infections, not only reason acute exacerbations of COPD, but also intensify and continue chronic inflammation in steady COPD through pathogen-associated molecular patterns. Present treatment plans are absorbed on titration of inhaled therapies such as long-acting bronchodilators, with cumulative interest in the usage of beleaguered biologic therapies meant at the underlying inflammatory devices. Educationssuggest that the mucosal IgA reply is abridged in COPD, and a lacking conveyance of IgA across the bronchial epithelium in COPD has been recognized, perhaps involving neutrophil proteinases, which may damage the Ig receptor mediating this transepithelialdirection-finding. Future instructions for investigation will emphasis elucidating the diverse inflammatory signatures foremost to asthma and chronic obstrucive, the development of reliable analytic standards and biomarkers of illness, and refining the clinical organization with an eye toward targeted therapies. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=imminology" title="imminology">imminology</a>, <a href="https://publications.waset.org/abstracts/search?q=asthma" title=" asthma"> asthma</a>, <a href="https://publications.waset.org/abstracts/search?q=COPD" title=" COPD"> COPD</a>, <a href="https://publications.waset.org/abstracts/search?q=CXCR2%20antagonists" title=" CXCR2 antagonists"> CXCR2 antagonists</a> </p> <a href="https://publications.waset.org/abstracts/143743/evaluation-of-immunology-of-asthma-chronic-obstructive" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/143743.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">162</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3383</span> The Effect of Thymoquinone and Sorafenib Combination on Hepatocellular Carcinoma Cell Line</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nabila%20N.%20El-Maraghy">Nabila N. El-Maraghy</a>, <a href="https://publications.waset.org/abstracts/search?q=Amany%20Essa"> Amany Essa</a>, <a href="https://publications.waset.org/abstracts/search?q=Yousra%20Abdel%E2%80%93Mottaleb"> Yousra Abdel–Mottaleb</a>, <a href="https://publications.waset.org/abstracts/search?q=Nada%20Ismail"> Nada Ismail</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The use of combination of chemotherapy and natural products to influence the cell death with low doses of chemotherapeutic agents and few side effects has recently emerged as a new method of cancer therapy. Aim: Evaluation the modulatory effect of Thymoquinone on HepG2 cells treated with Sorafenib. Methods: Hepatocellular Carcinoma HepG2 cell line was treated with Sorafenib and TQ individually and in combination. The effect of these treatments on cell viability (MTT assay), apoptosis (Expression of Caspase-3) and oxidative markers (GSH content and extent of lipid peroxidation) was determined. Results: When compared the effect of both agents alone and the combination of the IC50 of Sorafenib and the IC50 TQ, the combination resulted in reduction of cell inhibition and apoptosis and antagonize their actions on GSH content and extent of lipid peroxidation which are increased. This study showed potent anti-tumor activity of both TQ and Sorafenib separately on HepG2 but upon combination surprisingly they interacted and give antagonistic effect. Conclusion: Co-treatment resulted in antagonistic interaction between Sorafenib and Thymoquinone. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=antagonism" title="antagonism">antagonism</a>, <a href="https://publications.waset.org/abstracts/search?q=hepatocellular%20carcinoma" title=" hepatocellular carcinoma"> hepatocellular carcinoma</a>, <a href="https://publications.waset.org/abstracts/search?q=sorafenib" title=" sorafenib"> sorafenib</a>, <a href="https://publications.waset.org/abstracts/search?q=thymoquinone" title=" thymoquinone "> thymoquinone </a> </p> <a href="https://publications.waset.org/abstracts/48191/the-effect-of-thymoquinone-and-sorafenib-combination-on-hepatocellular-carcinoma-cell-line" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/48191.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">554</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3382</span> Reminiscence Therapy for Alzheimer’s Disease Restrained on Logistic Regression Based Linear Bootstrap Aggregating</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=P.%20S.%20Jagadeesh%20Kumar">P. S. Jagadeesh Kumar</a>, <a href="https://publications.waset.org/abstracts/search?q=Mingmin%20Pan"> Mingmin Pan</a>, <a href="https://publications.waset.org/abstracts/search?q=Xianpei%20Li"> Xianpei Li</a>, <a href="https://publications.waset.org/abstracts/search?q=Yanmin%20Yuan"> Yanmin Yuan</a>, <a href="https://publications.waset.org/abstracts/search?q=Tracy%20Lin%20Huan"> Tracy Lin Huan</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Researchers are doing enchanting research into the inherited features of Alzheimer’s disease and probable consistent therapies. In Alzheimer’s, memories are extinct in reverse order; memories formed lately are more transitory than those from formerly. Reminiscence therapy includes the conversation of past actions, trials and knowledges with another individual or set of people, frequently with the help of perceptible reminders such as photos, household and other acquainted matters from the past, music and collection of tapes. In this manuscript, the competence of reminiscence therapy for Alzheimer’s disease is measured using logistic regression based linear bootstrap aggregating. Logistic regression is used to envisage the experiential features of the patient’s memory through various therapies. Linear bootstrap aggregating shows better stability and accuracy of reminiscence therapy used in statistical classification and regression of memories related to validation therapy, supportive psychotherapy, sensory integration and simulated presence therapy. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Alzheimer%E2%80%99s%20disease" title="Alzheimer’s disease">Alzheimer’s disease</a>, <a href="https://publications.waset.org/abstracts/search?q=linear%20bootstrap%20aggregating" title=" linear bootstrap aggregating"> linear bootstrap aggregating</a>, <a href="https://publications.waset.org/abstracts/search?q=logistic%20regression" title=" logistic regression"> logistic regression</a>, <a href="https://publications.waset.org/abstracts/search?q=reminiscence%20therapy" title=" reminiscence therapy"> reminiscence therapy</a> </p> <a href="https://publications.waset.org/abstracts/79402/reminiscence-therapy-for-alzheimers-disease-restrained-on-logistic-regression-based-linear-bootstrap-aggregating" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/79402.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">309</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3381</span> Assessing the Clinicians’ Perspectives on Formulation with Minoxidil, Finasteride, and Capixyl™ in Androgenetic Alopecia: A Nationwide Dermatologist Survey</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sharma%20Aseem">Sharma Aseem</a>, <a href="https://publications.waset.org/abstracts/search?q=Dhurat%20Rachita"> Dhurat Rachita</a>, <a href="https://publications.waset.org/abstracts/search?q=Pawar%20Varsha"> Pawar Varsha</a>, <a href="https://publications.waset.org/abstracts/search?q=Khalse%20Manisha"> Khalse Manisha</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: Androgenetic alopecia (AGA) is a prevalent condition characterized by progressive hair thinning driven by genetic and androgen-related factors. The current FDA-approved treatments include oral finasteride and topical minoxidil, though many patients seek combination therapies to enhance results. This study aims to evaluate the effectiveness of a combination therapy involving Minoxidil, Finasteride, and Capixyl™ based on feedback from dermatologists. Methodology: A survey, validated by experts, was distributed to 29 leading dermatologists across India (in Tier 1 and 2 cities). The survey examined real-world clinical experiences, focusing on patient outcomes and the overall effectiveness of the mentioned formulation. Results: Among the surveyed dermatologists, 41.4% identified women aged 35-40 as the most frequently diagnosed with female pattern hair loss. The combination therapy with Minoxidil, Finasteride, and Capixyl™ was utilized by 34.5% of dermatologists for over 60 patients per month. The majority highlighted the benefits of this combination therapy, which acts via multiple mechanisms, such as vasodilation and dihydrotestosterone (DHT) receptor blockade, resulting in improved hair regrowth. Additionally, patients demonstrated better clinical outcomes, enhanced compliance, and fewer side effects. Demographically, younger patients, particularly those with AGA for less than 10 years, responded more positively to the treatment. Early intervention led to quicker and more significant results. Overall satisfaction among dermatologists was high, with 86.2% expressing positive feedback on the therapy. In terms of treatment outcomes, 51.7% of dermatologists observed visible results within 4-6 months, while 34.5% noticed a significant reduction in hair fall within 8-12 weeks. Improvements in scalp health were reported by 48.3%, and 51.7% saw an increased hair density within 3-4 months. Despite mild side effects such as scalp irritation, dryness, flaking, and occasional issues like folliculitis, headaches, itching, and redness, patient satisfaction remained high. Dermatologists reported that 93.1% of patients experienced faster and better hair regrowth with Capixyl™ compared to Minoxidil alone. Suggestions for improving the formulation included incorporating peptides like Saw Palmetto and enhancing product packaging to better meet patient needs. Discussion: The combination of Minoxidil, Finasteride, and Capixyl™ yielded positive clinical outcomes, especially in improving hair density, scalp health, and overall patient satisfaction. Dermatologists found that Capixyl™ peptides enhanced the therapeutic effect, promoting hair regrowth and improving compliance. While side effects were generally mild, there were suggestions to further improve the formulation by adding additional peptides like Saw Palmetto. Conclusion: The combination of Minoxidil and Finasteride fortified with Capixyl™ presents a promising therapeutic option for managing AGA. Dermatologists reported significant improvements in hair density, scalp health, and patient satisfaction. With its favorable efficacy and manageable side effects, this formulation proves to be a valuable addition to the treatment landscape for AGA. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=androgenetic%20alopecia" title="androgenetic alopecia">androgenetic alopecia</a>, <a href="https://publications.waset.org/abstracts/search?q=combination%20therapy" title=" combination therapy"> combination therapy</a>, <a href="https://publications.waset.org/abstracts/search?q=minoxidil" title=" minoxidil"> minoxidil</a>, <a href="https://publications.waset.org/abstracts/search?q=finasteride" title=" finasteride"> finasteride</a>, <a href="https://publications.waset.org/abstracts/search?q=capixyl" title=" capixyl"> capixyl</a> </p> <a href="https://publications.waset.org/abstracts/193209/assessing-the-clinicians-perspectives-on-formulation-with-minoxidil-finasteride-and-capixyl-in-androgenetic-alopecia-a-nationwide-dermatologist-survey" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/193209.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">13</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3380</span> Beneficial Effect of Biotin in Combination with Canagliflozin on High Fat Diet Induced Diabetes in Rats</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Rayhana%20Begum">Rayhana Begum</a>, <a href="https://publications.waset.org/abstracts/search?q=HongBin%20Wang"> HongBin Wang</a>, <a href="https://publications.waset.org/abstracts/search?q=Nur%20Alam%20%20Siddiquee"> Nur Alam Siddiquee</a>, <a href="https://publications.waset.org/abstracts/search?q=Md.Yasin%20Ahmed"> Md.Yasin Ahmed</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Biotin treatment has significant effects on blood glucose, and pharmacological doses of biotin improve hyperglycemia. The present study was aimed to investigate the efficacy and safety of biotin in combination with canagliflozin in improving glycemic control on High Fat Diet-induced diabetes in Rats. Thirty male rats were divided into five groups (six rats /group): control, high fat diet (HFD), canagliflozin (CAG), biotin (BIO), and CAG + BIO. The treatments with CAG and /or BIO significantly reduced the body weight gain, blood glucose and HbA1c levels, whereas CAG in combination with BIO revealed greater glycemic improvement than CAG monotherapy. The treatment with CAG and /or BIO causes significant change in lipid profile and CK level while the treatment with CAG in combination with BIO showed better results as compared with CAG monotherapy. Furthermore, combination of biotin with CAG improved the pancreatic and cardiac damage when compared with other treated groups. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=canagliflozin" title="canagliflozin">canagliflozin</a>, <a href="https://publications.waset.org/abstracts/search?q=biotin" title=" biotin"> biotin</a>, <a href="https://publications.waset.org/abstracts/search?q=HbA1c" title=" HbA1c"> HbA1c</a>, <a href="https://publications.waset.org/abstracts/search?q=lipid%20profile" title=" lipid profile"> lipid profile</a> </p> <a href="https://publications.waset.org/abstracts/122288/beneficial-effect-of-biotin-in-combination-with-canagliflozin-on-high-fat-diet-induced-diabetes-in-rats" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/122288.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">160</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3379</span> Potency Interaction using Simvastatin and Herbs Cholesterol Lowering Agent, Prevention of Unwanted Effect in Combination Hyperlipidemia Therapy</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Agung%20A.%20Ginanjar">Agung A. Ginanjar</a>, <a href="https://publications.waset.org/abstracts/search?q=Lilitasari"> Lilitasari</a>, <a href="https://publications.waset.org/abstracts/search?q=Indra%20Prasetya"> Indra Prasetya</a>, <a href="https://publications.waset.org/abstracts/search?q=Rizal%20R.%20Hanif"> Rizal R. Hanif</a>, <a href="https://publications.waset.org/abstracts/search?q=Yusrina%20Rismandini"> Yusrina Rismandini</a>, <a href="https://publications.waset.org/abstracts/search?q=Atina%20Hussaana"> Atina Hussaana</a>, <a href="https://publications.waset.org/abstracts/search?q=Nurita%20P.%20Sari"> Nurita P. Sari</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Hyperlipidemia is an increase of lipids and cholesterol in the blood that causes the formation of atherosklerosis. The recent pharmacological therapy nowadays is statin. Many Indonesian people use of medicinal plants. There are several medical plants that people always use to cure hyperlipidemia such as bulbs onion sabrang, areca nuts, and seed of fenugreek. Most people often use a combination therapy of conventional medicine and herbs to achieve the desired therapeutic effect of combination therapy. The use of combination therapy might cause the interaction of pharmacodynamic from those medicines so that it influences the pharmacological effect of one of medicine. The aim of this study is to know the interaction of simvastatin and a cholesterol-lowering herb seen in rats pharmacodynamic simvastatin phase. This research used post-test only controlled group design. Analysis of statistical data normality and homogenity were tested by Kolmogorov Smirnov. The ANOVA test is used when the data is obtained homogeneous but if it is found that the data are not homogeneous then kruskal-wallis test is used. Normal (63.196 mg/dl), negative (70.604 mg/dl), positive (62.512 mg/dl), areca nuts (56.564 mg/dl), fenugreek seed (47.538 ,g/dl), onion sabrang (62.312 mg/dl). The results prove that the combination of herbs and simvastatin did not have a significant difference (P>0,05). The conclusion of this study is that the combination of simvastatin and a cholesterol-lowering herb can cause some pharmacodynamic interactions such as a synergistic effect, antagonist, and a powerful additive, so that combination therapy is not more effective than single simvastatin therapy. The use of the combination therapy is not given in the same time. It would be better if there are some period of time when the combination therapy is applied. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=onion%20bulb%20sabrang" title="onion bulb sabrang">onion bulb sabrang</a>, <a href="https://publications.waset.org/abstracts/search?q=areca%20nuts" title=" areca nuts"> areca nuts</a>, <a href="https://publications.waset.org/abstracts/search?q=seed%20of%20fenugreek" title=" seed of fenugreek"> seed of fenugreek</a>, <a href="https://publications.waset.org/abstracts/search?q=interaction%20medicine" title=" interaction medicine"> interaction medicine</a>, <a href="https://publications.waset.org/abstracts/search?q=hyperlipidemia" title=" hyperlipidemia"> hyperlipidemia</a> </p> <a href="https://publications.waset.org/abstracts/33387/potency-interaction-using-simvastatin-and-herbs-cholesterol-lowering-agent-prevention-of-unwanted-effect-in-combination-hyperlipidemia-therapy" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/33387.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">530</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3378</span> Azaridachta indica (Neem) Seed Oil Effect in Experimental Arthritis: Biochemical Parameters Assessment</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sasan%20Khademnematolahi">Sasan Khademnematolahi</a>, <a href="https://publications.waset.org/abstracts/search?q=Kevine%20Kamga%20Silihe"> Kevine Kamga Silihe</a>, <a href="https://publications.waset.org/abstracts/search?q=Katar%C3%ADna%20Pru%C5%BEinsk%C3%A1"> Katarína Pružinská</a>, <a href="https://publications.waset.org/abstracts/search?q=Martina%20Chrastina"> Martina Chrastina</a>, <a href="https://publications.waset.org/abstracts/search?q=Elisabeth%20Louise%20Ndjengue%20Mindang"> Elisabeth Louise Ndjengue Mindang</a>, <a href="https://publications.waset.org/abstracts/search?q=Franti%C5%A1ek%20Dr%C3%A1fi"> František Dráfi</a>, <a href="https://publications.waset.org/abstracts/search?q=Katar%C3%ADna%20Bauerov%C3%A1"> Katarína Bauerová</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: In ethnomedicine, plant parts and compounds are traditionally utilized to treat many disorders. Azadirachta indica, known as Neem, has been traditionally used in medicinal practices. Due to the presence of bioactive substances such as nimbolide, azadirachtin, and gedunin, Neem offers a variety of medicinal properties, including anti-inflammatory and antioxidant properties. Through its effect on pathological inflammatory processes, supplementation with it could alleviate the symptoms of rheumatoid arthritis (RA). Methods: This research aimed to assess Neem seed oil's impact on rats with adjuvant arthritis. Three doses in monotherapy and two in combination with methotrexate (MTX) have been studied, and their effect was compared. Neem p.o. doses of 100, 200, and 300 mg/kg and MTX p.o. doses of 0.3 mg/kg were examined. After clinical parameters assessment, biochemical analysis was performed in plasma. Results: During the acute phase of the experimental arthritis (Day21), levels of MMP-9, MCP-1, and cytokines IL-1beta and IL-17A were measured. The positive results of inflammatory mediators evaluation in plasma encourage additional analysis also in related tissues to prove if Neem seed oil can be used as an adjuvant therapy for RA. Conclusion: In this study, the combination therapy of Neem with MTX was the most effective of all therapies investigated. Acknowledgement: SAIA PROJECT of Kevine Kamga Silihe, Slovakia-Cameroon 2023: “The effect of Crocus sativus L (Saffron), Azadirachta indica (Neem) and their main bioactives compounds in combinatory treatment with methotrexate on experimental arthritis”, VEGA 2/0079/24, VEGA 2/0136/20, VEGA 2/0126/23 and VEGA 2/0091/23. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=adjuvant" title="adjuvant">adjuvant</a>, <a href="https://publications.waset.org/abstracts/search?q=Neem" title=" Neem"> Neem</a>, <a href="https://publications.waset.org/abstracts/search?q=methotrexate" title=" methotrexate"> methotrexate</a>, <a href="https://publications.waset.org/abstracts/search?q=arthritis" title=" arthritis"> arthritis</a> </p> <a href="https://publications.waset.org/abstracts/186053/azaridachta-indica-neem-seed-oil-effect-in-experimental-arthritis-biochemical-parameters-assessment" class="btn btn-primary btn-sm">Procedia</a> <a 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