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id="mw-content-subtitle"><div class="cdx-message cdx-message--block cdx-message--warning mw-revision"><span class="cdx-message__icon"></span><div class="cdx-message__content"><div id="mw-revision-info-current"><p><b>This is the <a href="/wiki/Help:Page_history" title="Help:Page history">current revision</a> of this page, as edited by <span id="mw-revision-name"><a href="/wiki/User:Citation_bot" class="mw-userlink" title="User:Citation bot" data-mw-revid="1215921486"><bdi>Citation bot</bdi></a> <span class="mw-usertoollinks">(<a href="/wiki/User_talk:Citation_bot" class="mw-usertoollinks-talk" title="User talk:Citation bot">talk</a> | <a href="/wiki/Special:Contributions/Citation_bot" class="mw-usertoollinks-contribs" title="Special:Contributions/Citation bot">contribs</a>)</span></span> at <span id="mw-revision-date">23:17, 27 March 2024</span><span id="mw-revision-summary"> <span class="comment">(Added doi-access. | <a href="/wiki/Wikipedia:UCB" class="mw-redirect" 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Wikipedia:WikiProject_Academic_Journals/Journals_cited_by_Wikipedia/Sandbox | #UCB_webform_linked 171/187)</span></div></div><div id="mw-revision-nav">(<a href="/w/index.php?title=TSPAN7&diff=prev&oldid=1215921486" title="TSPAN7">diff</a>) <a href="/w/index.php?title=TSPAN7&direction=prev&oldid=1215921486" title="TSPAN7">← Previous revision</a> | Latest revision (diff) | Newer revision → (diff)</div></div></div></div></div> <div id="mw-content-text" class="mw-body-content"><div class="mw-content-ltr mw-parser-output" lang="en" dir="ltr"><div class="shortdescription nomobile noexcerpt noprint searchaux" style="display:none">Protein-coding gene in humans</div> <table class="infobox" style="width:26.4em"><tbody><tr><th colspan="4" style="text-align:center;font-size:125%;font-weight:bold">TSPAN7</th></tr><tr><td colspan="4" style="text-align:center"></td></tr><tr><th colspan="4" style="text-align:center;background-color:#ddd">Identifiers</th></tr><tr><th scope="row" style="background-color:#c3fdb8"><span class="plainlinks"><a href="/wiki/Gene_nomenclature" title="Gene nomenclature">Aliases</a></span></th><td colspan="3" style="background:#eee"><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/11854">TSPAN7</a></span>, A15, CCG-B7, CD231, DXS1692E, MRX58, MXS1, TALLA-1, TM4SF2, TM4SF2b, tetraspanin 7, XLID58</td></tr><tr><th scope="row" style="background-color:#c3fdb8">External IDs</th><td colspan="3" style="background-color:#eee"><span class="plainlinks"><a href="/wiki/Mendelian_Inheritance_in_Man" class="mw-redirect" title="Mendelian Inheritance in Man">OMIM</a>: <a rel="nofollow" class="external text" href="https://omim.org/entry/300096">300096</a>; <a href="/wiki/Mouse_Genome_Informatics" title="Mouse Genome Informatics">MGI</a>: <a rel="nofollow" class="external text" href="http://www.informatics.jax.org/marker/MGI:1298407">1298407</a>; <a href="/wiki/HomoloGene" title="HomoloGene">HomoloGene</a>: <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=homologene&dopt=HomoloGene&list_uids=20967">20967</a>; <a href="/wiki/GeneCards" title="GeneCards">GeneCards</a>: <a rel="nofollow" class="external text" href="https://www.genecards.org/cgi-bin/carddisp.pl?gene=TSPAN7">TSPAN7</a>; <a href="/wiki/Orthologous_MAtrix" title="Orthologous MAtrix">OMA</a>:<a rel="nofollow" class="external text" href="https://omabrowser.org/oma/vps/ENSG00000156298">TSPAN7 - orthologs</a></span></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><table class="collapsible collapsed" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th colspan="4" style="text-align:center;background-color:#ddd">Gene location (<a href="/wiki/Human_genome" title="Human genome">Human</a>)</th></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><span typeof="mw:File"><a href="/wiki/File:Ideogram_human_chromosome_X.svg" class="mw-file-description" title="X chromosome (human)"><img alt="X chromosome (human)" src="//upload.wikimedia.org/wikipedia/commons/thumb/1/18/Ideogram_human_chromosome_X.svg/300px-Ideogram_human_chromosome_X.svg.png" decoding="async" width="300" height="120" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/1/18/Ideogram_human_chromosome_X.svg/450px-Ideogram_human_chromosome_X.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/1/18/Ideogram_human_chromosome_X.svg/600px-Ideogram_human_chromosome_X.svg.png 2x" data-file-width="474" data-file-height="189" /></a></span></td></tr><tr><th scope="row" width="15%" style="background-color:#c3fdb8"><a href="/wiki/Chromosome" title="Chromosome">Chr.</a></th><td colspan="3" width="85%" style="background-color:#eee"><span class="plainlinks"><a href="/wiki/X_chromosome_(human)" class="mw-redirect" title="X chromosome (human)">X chromosome (human)</a><sup id="cite_ref-refGRCh38Ensembl_1-0" class="reference"><a href="#cite_note-refGRCh38Ensembl-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup></span></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><div align="center"><div style="position: relative; width: 300px;"><span typeof="mw:File"><a href="/wiki/File:Human_chromosome_X_ideogram.svg" class="mw-file-description" title="X chromosome (human)"><img alt="X chromosome (human)" src="//upload.wikimedia.org/wikipedia/commons/thumb/e/e0/Human_chromosome_X_ideogram.svg/300px-Human_chromosome_X_ideogram.svg.png" decoding="async" width="300" height="58" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/e/e0/Human_chromosome_X_ideogram.svg/450px-Human_chromosome_X_ideogram.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/e/e0/Human_chromosome_X_ideogram.svg/600px-Human_chromosome_X_ideogram.svg.png 2x" data-file-width="1125" data-file-height="216" /></a></span><div style="position: absolute; left: 67.407598256657px; top: 2px; padding: 0;"><span typeof="mw:File"><a href="/wiki/File:HSR_1996_II_3.5e.svg" class="mw-file-description" title="Genomic location for TSPAN7"><img alt="Genomic location for TSPAN7" src="//upload.wikimedia.org/wikipedia/commons/thumb/d/d8/HSR_1996_II_3.5e.svg/14px-HSR_1996_II_3.5e.svg.png" decoding="async" width="14" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/d8/HSR_1996_II_3.5e.svg/21px-HSR_1996_II_3.5e.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/d8/HSR_1996_II_3.5e.svg/28px-HSR_1996_II_3.5e.svg.png 2x" data-file-width="142" data-file-height="142" /></a></span></div><div style="position: absolute; left: 73.4px; top: 19px; padding: 0;"><span typeof="mw:File"><a href="/wiki/File:Red_rectangle_2x18.png" class="mw-file-description" title="Genomic location for TSPAN7"><img alt="Genomic location for TSPAN7" src="//upload.wikimedia.org/wikipedia/commons/6/6a/Red_rectangle_2x18.png" decoding="async" width="2" height="18" class="mw-file-element" data-file-width="2" data-file-height="18" /></a></span></div></div></div></td></tr><tr><th scope="row" rowspan="2" width="15%" style="background-color:#c3fdb8"><a href="/wiki/Locus_(genetics)" title="Locus (genetics)">Band</a></th><td rowspan="2" width="35%" style="background-color:#eee"><span class="plainlinks">Xp11.4</span></td><th scope="row" style="background-color:#c3fdb8">Start</th><td style="background-color:#eee"><span class="plainlinks">38,561,542 <a href="/wiki/Base_pair" title="Base pair">bp</a><sup id="cite_ref-refGRCh38Ensembl_1-1" class="reference"><a href="#cite_note-refGRCh38Ensembl-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup></span></td></tr><tr><th scope="row" style="background-color:#c3fdb8">End</th><td style="background-color:#eee"><span class="plainlinks">38,688,920 <a href="/wiki/Base_pair" title="Base pair">bp</a><sup id="cite_ref-refGRCh38Ensembl_1-2" class="reference"><a href="#cite_note-refGRCh38Ensembl-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup></span></td></tr></tbody></table></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><table class="collapsible collapsed" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th colspan="4" style="text-align:center;background-color:#ddd">Gene location (<a href="/wiki/Laboratory_mouse" title="Laboratory mouse">Mouse</a>)</th></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><span typeof="mw:File"><a href="/wiki/File:Ideogram_house_mouse_chromosome_X.svg" class="mw-file-description" title="X chromosome (mouse)"><img alt="X chromosome (mouse)" src="//upload.wikimedia.org/wikipedia/commons/thumb/5/59/Ideogram_house_mouse_chromosome_X.svg/260px-Ideogram_house_mouse_chromosome_X.svg.png" decoding="async" width="260" height="111" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/5/59/Ideogram_house_mouse_chromosome_X.svg/390px-Ideogram_house_mouse_chromosome_X.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/5/59/Ideogram_house_mouse_chromosome_X.svg/520px-Ideogram_house_mouse_chromosome_X.svg.png 2x" data-file-width="470" data-file-height="200" /></a></span></td></tr><tr><th scope="row" width="15%" style="background-color:#c3fdb8"><a href="/wiki/Chromosome" title="Chromosome">Chr.</a></th><td colspan="3" width="85%" style="background-color:#eee"><span class="plainlinks">X chromosome (mouse)<sup id="cite_ref-refGRCm38Ensembl_2-0" class="reference"><a href="#cite_note-refGRCm38Ensembl-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup></span></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><div align="center"><div style="position: relative; width: 300px;"><span typeof="mw:File"><a href="/wiki/File:Ideogram_of_house_mouse_chromosome_X.svg" class="mw-file-description" title="X chromosome (mouse)"><img alt="X chromosome (mouse)" src="//upload.wikimedia.org/wikipedia/commons/thumb/d/da/Ideogram_of_house_mouse_chromosome_X.svg/300px-Ideogram_of_house_mouse_chromosome_X.svg.png" decoding="async" width="300" height="58" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/da/Ideogram_of_house_mouse_chromosome_X.svg/450px-Ideogram_of_house_mouse_chromosome_X.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/da/Ideogram_of_house_mouse_chromosome_X.svg/600px-Ideogram_of_house_mouse_chromosome_X.svg.png 2x" data-file-width="1200" data-file-height="231" /></a></span><div style="position: absolute; left: 12.497774695909px; top: 2px; padding: 0;"><span typeof="mw:File"><a href="/wiki/File:HSR_1996_II_3.5e.svg" class="mw-file-description" title="Genomic location for TSPAN7"><img alt="Genomic location for TSPAN7" src="//upload.wikimedia.org/wikipedia/commons/thumb/d/d8/HSR_1996_II_3.5e.svg/14px-HSR_1996_II_3.5e.svg.png" decoding="async" width="14" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/d8/HSR_1996_II_3.5e.svg/21px-HSR_1996_II_3.5e.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/d8/HSR_1996_II_3.5e.svg/28px-HSR_1996_II_3.5e.svg.png 2x" data-file-width="142" data-file-height="142" /></a></span></div><div style="position: absolute; left: 18.5px; top: 19px; padding: 0;"><span typeof="mw:File"><a href="/wiki/File:Red_rectangle_2x18.png" class="mw-file-description" title="Genomic location for TSPAN7"><img alt="Genomic location for TSPAN7" src="//upload.wikimedia.org/wikipedia/commons/6/6a/Red_rectangle_2x18.png" decoding="async" width="2" height="18" class="mw-file-element" data-file-width="2" data-file-height="18" /></a></span></div></div></div></td></tr><tr><th scope="row" rowspan="2" width="15%" style="background-color:#c3fdb8"><a href="/wiki/Locus_(genetics)" title="Locus (genetics)">Band</a></th><td rowspan="2" width="35%" style="background-color:#eee"><span class="plainlinks">X|X A1.1</span></td><th scope="row" style="background-color:#c3fdb8">Start</th><td style="background-color:#eee"><span class="plainlinks">10,351,397 <a href="/wiki/Base_pair" title="Base pair">bp</a><sup id="cite_ref-refGRCm38Ensembl_2-1" class="reference"><a href="#cite_note-refGRCm38Ensembl-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup></span></td></tr><tr><th scope="row" style="background-color:#c3fdb8">End</th><td style="background-color:#eee"><span class="plainlinks">10,462,844 <a href="/wiki/Base_pair" title="Base pair">bp</a><sup id="cite_ref-refGRCm38Ensembl_2-2" class="reference"><a href="#cite_note-refGRCm38Ensembl-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup></span></td></tr></tbody></table></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><table class="collapsible collapsed" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th colspan="4" style="text-align:center;background-color:#ddd"><a href="/wiki/Gene_expression" title="Gene expression">RNA expression</a> pattern</th></tr><tr><th scope="row" style="background-color:#c3fdb8"><a rel="nofollow" class="external text" href="https://www.bgee.org/">Bgee</a></th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th><b><a href="/wiki/Human_genome" title="Human genome">Human</a></b></th><th><b><a href="/wiki/Laboratory_mouse" title="Laboratory mouse">Mouse</a> (ortholog)</b></th></tr><tr><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:center"><tbody><tr><td colspan="1"><span class="plainlinks" style="margin:-3px"><a rel="nofollow" class="external text" href="https://www.bgee.org/gene/ENSG00000156298">Top expressed in</a></span></td></tr><tr><td colspan="1"><div class="plainlinks" style="margin:-12px 0px -10px 0px"><ul style="line-height:15%;margin:9px"><li style="line-height: 137%;">caudate nucleus</li><br /><li style="line-height: 137%;">nucleus accumbens</li><br /><li style="line-height: 137%;">dorsolateral prefrontal cortex</li><br /><li style="line-height: 137%;">prefrontal cortex</li><br /><li style="line-height: 137%;">putamen</li><br /><li style="line-height: 137%;">right frontal lobe</li><br /><li style="line-height: 137%;">Brodmann area 9</li><br /><li style="line-height: 137%;">cerebellar cortex</li><br /><li style="line-height: 137%;">frontal pole</li><br /><li style="line-height: 137%;">cerebellar hemisphere</li></ul></div></td></tr></tbody></table></td><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:center"><tbody><tr><td colspan="1"><span class="plainlinks" style="margin:-3px"><a rel="nofollow" class="external text" href="https://www.bgee.org/gene/ENSMUSG00000058254">Top expressed in</a></span></td></tr><tr><td colspan="1"><div class="plainlinks" style="margin:-12px 0px -10px 0px"><ul style="line-height:15%;margin:9px"><li style="line-height: 137%;">dentate gyrus of hippocampal formation granule cell</li><br /><li style="line-height: 137%;">perirhinal cortex</li><br /><li style="line-height: 137%;">entorhinal cortex</li><br /><li style="line-height: 137%;">CA3 field</li><br /><li style="line-height: 137%;">superior frontal gyrus</li><br /><li style="line-height: 137%;">primary visual cortex</li><br /><li style="line-height: 137%;">nucleus of stria terminalis</li><br /><li style="line-height: 137%;">primary motor cortex</li><br /><li style="line-height: 137%;">dorsal striatum</li><br /><li style="line-height: 137%;">prefrontal cortex</li></ul></div></td></tr></tbody></table></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.bgee.org/gene/ENSG00000156298">More reference expression data</a></span></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:#c3fdb8"><a rel="nofollow" class="external text" href="http://biogps.org/">BioGPS</a></th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><td colspan="4" style="text-align:center;background-color:#eee"><span typeof="mw:File"><a href="/wiki/File:PBB_GE_TSPAN7_202242_at_fs.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/8/8b/PBB_GE_TSPAN7_202242_at_fs.png/250px-PBB_GE_TSPAN7_202242_at_fs.png" decoding="async" width="250" height="181" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/8/8b/PBB_GE_TSPAN7_202242_at_fs.png/375px-PBB_GE_TSPAN7_202242_at_fs.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/8/8b/PBB_GE_TSPAN7_202242_at_fs.png/500px-PBB_GE_TSPAN7_202242_at_fs.png 2x" data-file-width="732" data-file-height="530" /></a></span></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><span class="plainlinks"><a rel="nofollow" class="external text" href="http://biogps.org/gene/7102/">More reference expression data</a></span></td></tr></tbody></table></td></tr></tbody></table></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><table class="collapsible" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th colspan="4" style="text-align:center;background-color:#ddd"><a href="/wiki/Orthologs" class="mw-redirect" title="Orthologs">Orthologs</a></th></tr><tr><th scope="row" style="background-color:#c3fdb8">Species</th><td><b>Human</b></td><td><b>Mouse</b></td></tr><tr><th scope="row" style="background-color:#c3fdb8"><a href="/wiki/Entrez" title="Entrez">Entrez</a></th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=retrieve&dopt=default&list_uids=7102&rn=1">7102</a></p></td></tr></tbody></table></td><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=retrieve&dopt=default&list_uids=21912&rn=1">21912</a></p></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:#c3fdb8"><a href="/wiki/Ensembl" class="mw-redirect" title="Ensembl">Ensembl</a></th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="http://www.ensembl.org/Homo_sapiens/geneview?gene=ENSG00000156298;db=core">ENSG00000156298</a></p></td></tr></tbody></table></td><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="http://www.ensembl.org/Mus_musculus/geneview?gene=ENSMUSG00000058254;db=core">ENSMUSG00000058254</a></p></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:#c3fdb8"><a href="/wiki/UniProt" title="UniProt">UniProt</a></th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="https://www.uniprot.org/uniprot/P41732">P41732</a></p></td></tr></tbody></table></td><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="https://www.uniprot.org/uniprot/Q62283">Q62283</a></p></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:#c3fdb8">RefSeq (mRNA)</th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1" class="plainlinks"></th></tr><tr><td colspan="1"><p><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_004615">NM_004615</a></span></p></td></tr></tbody></table></td><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1" class="plainlinks"></th></tr><tr><td colspan="1"><p><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_019634">NM_019634</a></span></p></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:#c3fdb8">RefSeq (protein)</th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1" class="plainlinks"></th></tr><tr><td colspan="1"><p><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_004606">NP_004606</a></span></p></td></tr></tbody></table></td><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1" class="plainlinks"></th></tr><tr><td colspan="1"><p><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_062608">NP_062608</a></span></p></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:#c3fdb8">Location (UCSC)</th><td><span class="plainlinks"><a rel="nofollow" class="external text" href="https://genome.ucsc.edu/cgi-bin/hgTracks?org=Human&db=hg38&position=chrX:38561542-38688920">Chr X: 38.56 – 38.69 Mb</a></span></td><td><span class="plainlinks"><a rel="nofollow" class="external text" href="https://genome.ucsc.edu/cgi-bin/hgTracks?org=Mouse&db=mm0&position=chrX:10351397-10462844">Chr X: 10.35 – 10.46 Mb</a></span></td></tr><tr><th scope="row" style="background-color:#c3fdb8"><a href="/wiki/PubMed" title="PubMed">PubMed</a> search</th><td><span class="plainlinks"><sup id="cite_ref-3" class="reference"><a href="#cite_note-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup></span></td><td><span class="plainlinks"><sup id="cite_ref-4" class="reference"><a href="#cite_note-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup></span></td></tr></tbody></table></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><a href="/wiki/Wikidata" title="Wikidata">Wikidata</a></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><table style="padding:0;border:none;margin:0;width:100%;text-align:center"><tbody><tr><td colspan="2" style="background-color:#eee;text-align:center"><a href="https://www.wikidata.org/wiki/Q18032014" class="extiw" title="d:Q18032014">View/Edit Human</a></td><td colspan="2" style="background-color:#eee;text-align:center"><a href="https://www.wikidata.org/wiki/Q18255033" class="extiw" title="d:Q18255033">View/Edit Mouse</a></td></tr></tbody></table></td></tr></tbody></table> <p><b>Tetraspanin-7</b> is a <a href="/wiki/Protein" title="Protein">protein</a> that in humans is encoded by the <i>TSPAN7</i> <a href="/wiki/Gene" title="Gene">gene</a>.<sup id="cite_ref-pmid12070254_5-0" class="reference"><a href="#cite_note-pmid12070254-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-entrez_6-0" class="reference"><a href="#cite_note-entrez-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup> </p><p>The protein encoded by this gene is a member of the <a href="/wiki/Transmembrane_4_superfamily" class="mw-redirect" title="Transmembrane 4 superfamily">transmembrane 4</a> superfamily, also known as the <a href="/wiki/Tetraspanin" title="Tetraspanin">tetraspanin</a> family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and may have a role in the control of neurite outgrowth. It is known to complex with integrins. This gene is associated with <a href="/wiki/X-linked_mental_retardation" class="mw-redirect" title="X-linked mental retardation">X-linked mental retardation</a> and neuropsychiatric diseases such as <a href="/wiki/Huntington%27s_chorea" class="mw-redirect" title="Huntington's chorea">Huntington's chorea</a>, <a href="/wiki/Fragile_X_syndrome" title="Fragile X syndrome">fragile X syndrome</a> and <a href="/wiki/Myotonic_dystrophy" title="Myotonic dystrophy">myotonic dystrophy</a>.<sup id="cite_ref-entrez_6-1" class="reference"><a href="#cite_note-entrez-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup> More recently, it has been identified as a key immune system target in type 1 diabetes.<sup id="cite_ref-Diabetes_7-0" class="reference"><a href="#cite_note-Diabetes-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="References">References</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=TSPAN7&action=edit&section=1" title="Edit section: References"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1239543626">.mw-parser-output .reflist{margin-bottom:0.5em;list-style-type:decimal}@media screen{.mw-parser-output .reflist{font-size:90%}}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output .reflist-columns-2{column-width:30em}.mw-parser-output .reflist-columns-3{column-width:25em}.mw-parser-output .reflist-columns{margin-top:0.3em}.mw-parser-output .reflist-columns ol{margin-top:0}.mw-parser-output .reflist-columns li{page-break-inside:avoid;break-inside:avoid-column}.mw-parser-output .reflist-upper-alpha{list-style-type:upper-alpha}.mw-parser-output .reflist-upper-roman{list-style-type:upper-roman}.mw-parser-output .reflist-lower-alpha{list-style-type:lower-alpha}.mw-parser-output .reflist-lower-greek{list-style-type:lower-greek}.mw-parser-output .reflist-lower-roman{list-style-type:lower-roman}</style><div class="reflist"> <div class="mw-references-wrap"><ol class="references"> <li id="cite_note-refGRCh38Ensembl-1"><span class="mw-cite-backlink">^ <a href="#cite_ref-refGRCh38Ensembl_1-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-refGRCh38Ensembl_1-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-refGRCh38Ensembl_1-2"><sup><i><b>c</b></i></sup></a></span> <span class="reference-text"><a rel="nofollow" class="external text" href="http://May2017.archive.ensembl.org/Homo_sapiens/Gene/Summary?db=core;g=ENSG00000156298">GRCh38: Ensembl release 89: ENSG00000156298</a> – <a href="/wiki/Ensembl_genome_database_project" title="Ensembl genome database project">Ensembl</a>, May 2017</span> </li> <li id="cite_note-refGRCm38Ensembl-2"><span class="mw-cite-backlink">^ <a href="#cite_ref-refGRCm38Ensembl_2-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-refGRCm38Ensembl_2-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-refGRCm38Ensembl_2-2"><sup><i><b>c</b></i></sup></a></span> <span class="reference-text"><a rel="nofollow" class="external text" href="http://May2017.archive.ensembl.org/Mus_musculus/Gene/Summary?db=core;g=ENSMUSG00000058254">GRCm38: Ensembl release 89: ENSMUSG00000058254</a> – <a href="/wiki/Ensembl_genome_database_project" title="Ensembl genome database project">Ensembl</a>, May 2017</span> </li> <li id="cite_note-3"><span class="mw-cite-backlink"><b><a href="#cite_ref-3">^</a></b></span> <span class="reference-text"><style data-mw-deduplicate="TemplateStyles:r1238218222">.mw-parser-output cite.citation{font-style:inherit;word-wrap:break-word}.mw-parser-output .citation q{quotes:"\"""\"""'""'"}.mw-parser-output .citation:target{background-color:rgba(0,127,255,0.133)}.mw-parser-output .id-lock-free.id-lock-free a{background:url("//upload.wikimedia.org/wikipedia/commons/6/65/Lock-green.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-limited.id-lock-limited a,.mw-parser-output .id-lock-registration.id-lock-registration a{background:url("//upload.wikimedia.org/wikipedia/commons/d/d6/Lock-gray-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-subscription.id-lock-subscription a{background:url("//upload.wikimedia.org/wikipedia/commons/a/aa/Lock-red-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .cs1-ws-icon a{background:url("//upload.wikimedia.org/wikipedia/commons/4/4c/Wikisource-logo.svg")right 0.1em center/12px no-repeat}body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-free a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-limited a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-registration a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-subscription a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .cs1-ws-icon a{background-size:contain;padding:0 1em 0 0}.mw-parser-output .cs1-code{color:inherit;background:inherit;border:none;padding:inherit}.mw-parser-output .cs1-hidden-error{display:none;color:var(--color-error,#d33)}.mw-parser-output .cs1-visible-error{color:var(--color-error,#d33)}.mw-parser-output .cs1-maint{display:none;color:#085;margin-left:0.3em}.mw-parser-output .cs1-kern-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right{padding-right:0.2em}.mw-parser-output .citation .mw-selflink{font-weight:inherit}@media screen{.mw-parser-output .cs1-format{font-size:95%}html.skin-theme-clientpref-night .mw-parser-output .cs1-maint{color:#18911f}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .cs1-maint{color:#18911f}}</style><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Link&LinkName=gene_pubmed&from_uid=7102">"Human PubMed Reference:"</a>. <i>National Center for Biotechnology Information, U.S. National Library of Medicine</i>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=National+Center+for+Biotechnology+Information%2C+U.S.+National+Library+of+Medicine&rft.atitle=Human+PubMed+Reference%3A&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fsites%2Fentrez%3Fdb%3Dgene%26cmd%3DLink%26LinkName%3Dgene_pubmed%26from_uid%3D7102&rfr_id=info%3Asid%2Fen.wikipedia.org%3ATSPAN7" class="Z3988"></span></span> </li> <li id="cite_note-4"><span class="mw-cite-backlink"><b><a href="#cite_ref-4">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Link&LinkName=gene_pubmed&from_uid=21912">"Mouse PubMed Reference:"</a>. <i>National Center for Biotechnology Information, U.S. National Library of Medicine</i>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=National+Center+for+Biotechnology+Information%2C+U.S.+National+Library+of+Medicine&rft.atitle=Mouse+PubMed+Reference%3A&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fsites%2Fentrez%3Fdb%3Dgene%26cmd%3DLink%26LinkName%3Dgene_pubmed%26from_uid%3D21912&rfr_id=info%3Asid%2Fen.wikipedia.org%3ATSPAN7" class="Z3988"></span></span> </li> <li id="cite_note-pmid12070254-5"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid12070254_5-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFAbidiHolinski-FederRittingerKooy2002" class="citation journal cs1">Abidi FE, Holinski-Feder E, Rittinger O, Kooy F, Lubs HA, Stevenson RE, Schwartz CE (Jun 2002). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1735161">"A novel 2 bp deletion in the TM4SF2 gene is associated with MRX58"</a>. <i>J Med Genet</i>. <b>39</b> (6): 430–3. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1136%2Fjmg.39.6.430">10.1136/jmg.39.6.430</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1735161">1735161</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/12070254">12070254</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=J+Med+Genet&rft.atitle=A+novel+2+bp+deletion+in+the+TM4SF2+gene+is+associated+with+MRX58&rft.volume=39&rft.issue=6&rft.pages=430-3&rft.date=2002-06&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC1735161%23id-name%3DPMC&rft_id=info%3Apmid%2F12070254&rft_id=info%3Adoi%2F10.1136%2Fjmg.39.6.430&rft.aulast=Abidi&rft.aufirst=FE&rft.au=Holinski-Feder%2C+E&rft.au=Rittinger%2C+O&rft.au=Kooy%2C+F&rft.au=Lubs%2C+HA&rft.au=Stevenson%2C+RE&rft.au=Schwartz%2C+CE&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC1735161&rfr_id=info%3Asid%2Fen.wikipedia.org%3ATSPAN7" class="Z3988"></span></span> </li> <li id="cite_note-entrez-6"><span class="mw-cite-backlink">^ <a href="#cite_ref-entrez_6-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-entrez_6-1"><sup><i><b>b</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7102">"Entrez Gene: TSPAN7 tetraspanin 7"</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Entrez+Gene%3A+TSPAN7+tetraspanin+7&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fsites%2Fentrez%3FDb%3Dgene%26Cmd%3DShowDetailView%26TermToSearch%3D7102&rfr_id=info%3Asid%2Fen.wikipedia.org%3ATSPAN7" class="Z3988"></span></span> </li> <li id="cite_note-Diabetes-7"><span class="mw-cite-backlink"><b><a href="#cite_ref-Diabetes_7-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFMcLaughlinRichardson2016" class="citation journal cs1">McLaughlin, KA; Richardson, CC (16 March 2016). <a rel="nofollow" class="external text" href="https://doi.org/10.2337%2Fdb15-1058">"Identification of Tetraspanin-7 as a Target of Autoantibodies in Type 1 Diabetes"</a>. <i>Diabetes</i>. <b>65</b> (6): 1690–8. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.2337%2Fdb15-1058">10.2337/db15-1058</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/26953162">26953162</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Diabetes&rft.atitle=Identification+of+Tetraspanin-7+as+a+Target+of+Autoantibodies+in+Type+1+Diabetes&rft.volume=65&rft.issue=6&rft.pages=1690-8&rft.date=2016-03-16&rft_id=info%3Adoi%2F10.2337%2Fdb15-1058&rft_id=info%3Apmid%2F26953162&rft.aulast=McLaughlin&rft.aufirst=KA&rft.au=Richardson%2C+CC&rft_id=https%3A%2F%2Fdoi.org%2F10.2337%252Fdb15-1058&rfr_id=info%3Asid%2Fen.wikipedia.org%3ATSPAN7" class="Z3988"></span></span> </li> </ol></div></div> <div class="mw-heading mw-heading2"><h2 id="Further_reading">Further reading</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=TSPAN7&action=edit&section=2" title="Edit section: Further reading"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1239549316">.mw-parser-output .refbegin{margin-bottom:0.5em}.mw-parser-output .refbegin-hanging-indents>ul{margin-left:0}.mw-parser-output .refbegin-hanging-indents>ul>li{margin-left:0;padding-left:3.2em;text-indent:-3.2em}.mw-parser-output .refbegin-hanging-indents ul,.mw-parser-output .refbegin-hanging-indents ul li{list-style:none}@media(max-width:720px){.mw-parser-output .refbegin-hanging-indents>ul>li{padding-left:1.6em;text-indent:-1.6em}}.mw-parser-output .refbegin-columns{margin-top:0.3em}.mw-parser-output .refbegin-columns ul{margin-top:0}.mw-parser-output .refbegin-columns li{page-break-inside:avoid;break-inside:avoid-column}@media screen{.mw-parser-output .refbegin{font-size:90%}}</style><div class="refbegin refbegin-columns references-column-width" style="column-width: 30em"> <ul><li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFCastellví-BelMilà2001" class="citation journal cs1">Castellví-Bel S, Milà M (2001). "Genes responsible for nonspecific mental retardation". <i>Mol. Genet. Metab</i>. <b>72</b> (2): 104–8. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1006%2Fmgme.2000.3128">10.1006/mgme.2000.3128</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/11161835">11161835</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Mol.+Genet.+Metab.&rft.atitle=Genes+responsible+for+nonspecific+mental+retardation&rft.volume=72&rft.issue=2&rft.pages=104-8&rft.date=2001&rft_id=info%3Adoi%2F10.1006%2Fmgme.2000.3128&rft_id=info%3Apmid%2F11161835&rft.aulast=Castellv%C3%AD-Bel&rft.aufirst=S&rft.au=Mil%C3%A0%2C+M&rfr_id=info%3Asid%2Fen.wikipedia.org%3ATSPAN7" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFBerditchevski_F2002" class="citation journal cs1">Berditchevski F (2002). "Complexes of tetraspanins with integrins: more than meets the eye". <i>J. Cell Sci</i>. <b>114</b> (Pt 23): 4143–51. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1242%2Fjcs.114.23.4143">10.1242/jcs.114.23.4143</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/11739647">11739647</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=J.+Cell+Sci.&rft.atitle=Complexes+of+tetraspanins+with+integrins%3A+more+than+meets+the+eye&rft.volume=114&rft.issue=Pt+23&rft.pages=4143-51&rft.date=2002&rft_id=info%3Adoi%2F10.1242%2Fjcs.114.23.4143&rft_id=info%3Apmid%2F11739647&rft.au=Berditchevski+F&rfr_id=info%3Asid%2Fen.wikipedia.org%3ATSPAN7" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFTakagiFujikawaImai1995" class="citation journal cs1">Takagi S, Fujikawa K, Imai T, et al. (1995). "Identification of a highly specific surface marker of T-cell acute lymphoblastic leukemia and neuroblastoma as a new member of the transmembrane 4 superfamily". <i>Int. J. Cancer</i>. <b>61</b> (5): 706–15. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1002%2Fijc.2910610519">10.1002/ijc.2910610519</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/7768645">7768645</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:20745142">20745142</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Int.+J.+Cancer&rft.atitle=Identification+of+a+highly+specific+surface+marker+of+T-cell+acute+lymphoblastic+leukemia+and+neuroblastoma+as+a+new+member+of+the+transmembrane+4+superfamily&rft.volume=61&rft.issue=5&rft.pages=706-15&rft.date=1995&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A20745142%23id-name%3DS2CID&rft_id=info%3Apmid%2F7768645&rft_id=info%3Adoi%2F10.1002%2Fijc.2910610519&rft.aulast=Takagi&rft.aufirst=S&rft.au=Fujikawa%2C+K&rft.au=Imai%2C+T&rfr_id=info%3Asid%2Fen.wikipedia.org%3ATSPAN7" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFVirtanevaEmiMarken1994" class="citation journal cs1">Virtaneva KI, Emi N, Marken JS, et al. (1994). "Chromosomal localization of three human genes coding for A15, L6, and S5.7 (TAPA1): all members of the transmembrane 4 superfamily of proteins". <i>Immunogenetics</i>. <b>39</b> (5): 329–34. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1007%2FBF00189229">10.1007/BF00189229</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/8168850">8168850</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:22971645">22971645</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Immunogenetics&rft.atitle=Chromosomal+localization+of+three+human+genes+coding+for+A15%2C+L6%2C+and+S5.7+%28TAPA1%29%3A+all+members+of+the+transmembrane+4+superfamily+of+proteins&rft.volume=39&rft.issue=5&rft.pages=329-34&rft.date=1994&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A22971645%23id-name%3DS2CID&rft_id=info%3Apmid%2F8168850&rft_id=info%3Adoi%2F10.1007%2FBF00189229&rft.aulast=Virtaneva&rft.aufirst=KI&rft.au=Emi%2C+N&rft.au=Marken%2C+JS&rfr_id=info%3Asid%2Fen.wikipedia.org%3ATSPAN7" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFLiMcInnisMargolis1993" class="citation journal cs1">Li SH, McInnis MG, Margolis RL, et al. 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Biol</i>. <b>3</b> (1): 89. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1038%2Fmsb4100134">10.1038/msb4100134</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1847948">1847948</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/17353931">17353931</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Mol.+Syst.+Biol.&rft.atitle=Large-scale+mapping+of+human+protein%E2%80%93protein+interactions+by+mass+spectrometry&rft.volume=3&rft.issue=1&rft.pages=89&rft.date=2007&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC1847948%23id-name%3DPMC&rft_id=info%3Apmid%2F17353931&rft_id=info%3Adoi%2F10.1038%2Fmsb4100134&rft.aulast=Ewing&rft.aufirst=RM&rft.au=Chu%2C+P&rft.au=Elisma%2C+F&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC1847948&rfr_id=info%3Asid%2Fen.wikipedia.org%3ATSPAN7" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFMcLaughlinRichardsonRavishankar2007" class="citation journal cs1">McLaughlin KA, Richardson CC, Ravishankar A, et al. (2007). <a rel="nofollow" class="external text" href="https://doi.org/10.2337%2Fdb15-1058">"Identification of Tetraspanin-7 as a Target of Autoantibodies in Type 1 Diabetes"</a>. <i>Diabetes</i>. <b>65</b> (6): 1690–8. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.2337%2Fdb15-1058">10.2337/db15-1058</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/26953162">26953162</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Diabetes&rft.atitle=Identification+of+Tetraspanin-7+as+a+Target+of+Autoantibodies+in+Type+1+Diabetes&rft.volume=65&rft.issue=6&rft.pages=1690-8&rft.date=2007&rft_id=info%3Adoi%2F10.2337%2Fdb15-1058&rft_id=info%3Apmid%2F26953162&rft.aulast=McLaughlin&rft.aufirst=KA&rft.au=Richardson%2C+CC&rft.au=Ravishankar%2C+A&rft_id=https%3A%2F%2Fdoi.org%2F10.2337%252Fdb15-1058&rfr_id=info%3Asid%2Fen.wikipedia.org%3ATSPAN7" class="Z3988"></span></li></ul> </div> <div class="navbox-styles"><style data-mw-deduplicate="TemplateStyles:r1129693374">.mw-parser-output .hlist dl,.mw-parser-output .hlist ol,.mw-parser-output .hlist ul{margin:0;padding:0}.mw-parser-output .hlist dd,.mw-parser-output .hlist dt,.mw-parser-output .hlist li{margin:0;display:inline}.mw-parser-output .hlist.inline,.mw-parser-output .hlist.inline dl,.mw-parser-output .hlist.inline ol,.mw-parser-output .hlist.inline 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href="/wiki/Template:Other_cell_membrane_proteins" title="Template:Other cell membrane proteins"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Other_cell_membrane_proteins" title="Template talk:Other cell membrane proteins"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Other_cell_membrane_proteins" title="Special:EditPage/Template:Other cell membrane proteins"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Protein:_cell_membrane_proteins_(other_than_Cell_surface_receptor,_enzymes,_and_cytoskeleton)" style="font-size:114%;margin:0 4em"><a href="/wiki/Protein" title="Protein">Protein</a>: cell <a href="/wiki/Membrane_protein" title="Membrane protein">membrane proteins</a> (other than <a href="/wiki/Cell_surface_receptor" title="Cell surface receptor">Cell surface receptor</a>, <a href="/wiki/Enzyme" title="Enzyme">enzymes</a>, and <a href="/wiki/Cytoskeleton" title="Cytoskeleton">cytoskeleton</a>)</div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Arrestin" title="Arrestin">Arrestin</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/SAG_(gene)" title="SAG (gene)">SAG</a></li> <li><a href="/wiki/Arrestin_beta_1" title="Arrestin beta 1">ARRB1</a></li> <li><a href="/wiki/Arrestin_beta_2" title="Arrestin beta 2">ARRB2</a></li> <li><a href="/wiki/ARR3" title="ARR3">ARR3</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Membrane-spanning_4A" title="Membrane-spanning 4A">Membrane-spanning 4A</a></th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/CD20" title="CD20">MS4A1</a></li> <li><a href="/wiki/MS4A2" title="MS4A2">MS4A2</a></li> <li><a href="/wiki/MS4A3" title="MS4A3">MS4A3</a></li> <li><a href="/w/index.php?title=MS4A4A&action=edit&redlink=1" class="new" title="MS4A4A (page does not exist)">MS4A4A</a></li> <li><a href="/w/index.php?title=MS4A4E&action=edit&redlink=1" class="new" title="MS4A4E (page does not exist)">MS4A4E</a></li> <li><a href="/w/index.php?title=MS4A5&action=edit&redlink=1" class="new" title="MS4A5 (page does not exist)">MS4A5</a></li> <li><a href="/w/index.php?title=MS4A6A&action=edit&redlink=1" class="new" title="MS4A6A (page does not exist)">MS4A6A</a></li> <li><a href="/w/index.php?title=MS4A6E&action=edit&redlink=1" class="new" title="MS4A6E (page does not exist)">MS4A6E</a></li> <li><a href="/wiki/MS4A7" title="MS4A7">MS4A7</a></li> <li><a href="/w/index.php?title=MS4A8B&action=edit&redlink=1" class="new" title="MS4A8B (page does not exist)">MS4A8B</a></li> <li><a href="/w/index.php?title=MS4A9&action=edit&redlink=1" class="new" title="MS4A9 (page does not exist)">MS4A9</a></li> <li><a href="/w/index.php?title=MS4A10&action=edit&redlink=1" class="new" title="MS4A10 (page does not exist)">MS4A10</a></li> <li><a href="/w/index.php?title=MS4A12&action=edit&redlink=1" class="new" title="MS4A12 (page does not exist)">MS4A12</a></li> <li><a href="/w/index.php?title=MS4A13&action=edit&redlink=1" class="new" title="MS4A13 (page does not exist)">MS4A13</a></li> <li><a href="/w/index.php?title=MS4A14&action=edit&redlink=1" class="new" title="MS4A14 (page does not exist)">MS4A14</a></li> <li><a href="/w/index.php?title=MS4A15&action=edit&redlink=1" class="new" title="MS4A15 (page does not exist)">MS4A15</a></li> <li><a href="/w/index.php?title=MS4A18&action=edit&redlink=1" class="new" title="MS4A18 (page does not exist)">MS4A18</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Myelin" title="Myelin">Myelin</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Myelin_basic_protein" title="Myelin basic protein">Myelin basic protein</a> <ul><li><a href="/wiki/PMP2" title="PMP2">PMP2</a></li></ul></li> <li><a href="/wiki/Myelin_proteolipid_protein" title="Myelin proteolipid protein">Myelin proteolipid protein</a> <ul><li><a href="/wiki/Proteolipid_protein_1" title="Proteolipid protein 1">PLP1</a></li></ul></li> <li><a href="/wiki/Myelin_oligodendrocyte_glycoprotein" title="Myelin oligodendrocyte glycoprotein">Myelin oligodendrocyte glycoprotein</a></li> <li><a href="/wiki/Myelin-associated_glycoprotein" title="Myelin-associated glycoprotein">Myelin-associated glycoprotein</a></li> <li><a href="/wiki/Myelin_protein_zero" title="Myelin protein zero">Myelin protein zero</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Pulmonary_surfactant" title="Pulmonary surfactant">Pulmonary surfactant</a></th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Pulmonary_surfactant-associated_protein_B" class="mw-redirect" title="Pulmonary surfactant-associated protein B">Pulmonary surfactant-associated protein B</a></li> <li><a href="/wiki/Pulmonary_surfactant-associated_protein_C" class="mw-redirect" title="Pulmonary surfactant-associated protein C">Pulmonary surfactant-associated protein C</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Tetraspanin" title="Tetraspanin">Tetraspanin</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/w/index.php?title=TSPAN1&action=edit&redlink=1" class="new" title="TSPAN1 (page does not exist)">TSPAN1</a></li> <li><a href="/wiki/TSPAN2" title="TSPAN2">TSPAN2</a></li> <li><a href="/wiki/TSPAN3" title="TSPAN3">TSPAN3</a></li> <li><a href="/wiki/TSPAN4" title="TSPAN4">TSPAN4</a></li> <li><a href="/w/index.php?title=TSPAN5&action=edit&redlink=1" class="new" title="TSPAN5 (page does not exist)">TSPAN5</a></li> <li><a href="/wiki/TSPAN6" title="TSPAN6">TSPAN6</a></li> <li><a class="mw-selflink selflink">TSPAN7</a></li> <li><a href="/wiki/TSPAN8" title="TSPAN8">TSPAN8</a></li> <li><a href="/wiki/TSPAN9" class="mw-redirect" title="TSPAN9">TSPAN9</a></li> <li><a href="/wiki/TSPAN10" class="mw-redirect" title="TSPAN10">TSPAN10</a></li> <li><a href="/w/index.php?title=TSPAN11&action=edit&redlink=1" class="new" title="TSPAN11 (page does not exist)">TSPAN11</a></li> <li><a href="/wiki/TSPAN12" title="TSPAN12">TSPAN12</a></li> <li><a href="/wiki/TSPAN13" title="TSPAN13">TSPAN13</a></li> <li><a href="/wiki/TSPAN14" title="TSPAN14">TSPAN14</a></li> <li><a href="/w/index.php?title=TSPAN15&action=edit&redlink=1" class="new" title="TSPAN15 (page does not exist)">TSPAN15</a></li> <li><a href="/w/index.php?title=TSPAN16&action=edit&redlink=1" class="new" title="TSPAN16 (page does not exist)">TSPAN16</a></li> <li><a href="/w/index.php?title=TSPAN17&action=edit&redlink=1" class="new" title="TSPAN17 (page does not exist)">TSPAN17</a></li> <li><a href="/wiki/TSPAN18" class="mw-redirect" title="TSPAN18">TSPAN18</a></li> <li><a href="/w/index.php?title=TSPAN19&action=edit&redlink=1" class="new" title="TSPAN19 (page does not exist)">TSPAN19</a></li> <li><a href="/w/index.php?title=TSPAN20&action=edit&redlink=1" class="new" title="TSPAN20 (page does not exist)">TSPAN20</a></li> <li><a href="/wiki/TSPAN21" class="mw-redirect" title="TSPAN21">TSPAN21</a></li> <li><a href="/w/index.php?title=TSPAN22&action=edit&redlink=1" class="new" title="TSPAN22 (page does not exist)">TSPAN22</a></li> <li><a href="/wiki/TSPAN23" class="mw-redirect" title="TSPAN23">TSPAN23</a></li> <li><a href="/wiki/CD151" title="CD151">TSPAN24</a></li> <li><a href="/wiki/CD53" title="CD53">TSPAN25</a></li> <li><a href="/wiki/CD37" title="CD37">TSPAN26</a></li> <li><a href="/wiki/CD82_(gene)" title="CD82 (gene)">TSPAN27</a></li> <li><a href="/wiki/CD81" title="CD81">TSPAN28</a></li> <li><a href="/wiki/CD9" title="CD9">TSPAN29</a></li> <li><a href="/wiki/CD63" title="CD63">TSPAN30</a></li> <li><a href="/wiki/TSPAN31" title="TSPAN31">TSPAN31</a></li> <li><a href="/wiki/TSPAN32" title="TSPAN32">TSPAN32</a></li> <li><a href="/w/index.php?title=TSPAN33&action=edit&redlink=1" class="new" title="TSPAN33 (page does not exist)">TSPAN33</a></li> <li><a href="/w/index.php?title=TSPAN34&action=edit&redlink=1" class="new" title="TSPAN34 (page does not exist)">TSPAN34</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Other/ungrouped</th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Calnexin" title="Calnexin">Calnexin</a></li> <li><a href="/wiki/LDL-receptor-related_protein-associated_protein" title="LDL-receptor-related protein-associated protein">LDL-receptor-related protein-associated protein</a></li> <li><a href="/wiki/Merlin_(protein)" title="Merlin (protein)">Neurofibromin 2</a></li> <li><a href="/wiki/Presenilin" title="Presenilin">Presenilin</a> <ul><li><a href="/wiki/PSEN1" class="mw-redirect" title="PSEN1">PSEN1</a></li> <li><a href="/wiki/PSEN2" class="mw-redirect" title="PSEN2">PSEN2</a></li></ul></li> <li><a href="/wiki/HFE_(gene)" title="HFE (gene)">HFE</a></li> <li><a href="/wiki/Phospholipid_scramblase" title="Phospholipid scramblase">Phospholipid transfer proteins</a></li> <li><a href="/wiki/Dysferlin" title="Dysferlin">Dysferlin</a></li> <li><a href="/wiki/STRC" title="STRC">STRC</a></li> <li><a href="/wiki/OTOF" class="mw-redirect" title="OTOF">OTOF</a></li></ul> </div></td></tr><tr><td class="navbox-abovebelow" colspan="2" style="padding:0;"><div><i>see also <a href="/wiki/Template:Other_cell_membrane_protein_disorders" title="Template:Other cell membrane protein disorders">other cell membrane protein disorders</a></i></div></td></tr></tbody></table></div> <p><br /> </p> <style data-mw-deduplicate="TemplateStyles:r1012311289">.mw-parser-output .asbox{position:relative;overflow:hidden}.mw-parser-output .asbox table{background:transparent}.mw-parser-output .asbox p{margin:0}.mw-parser-output .asbox p+p{margin-top:0.25em}.mw-parser-output .asbox-body{font-style:italic}.mw-parser-output .asbox-note{font-size:smaller}.mw-parser-output .asbox .navbar{position:absolute;top:-0.75em;right:1em;display:none}</style><div role="note" class="metadata plainlinks asbox stub"><table role="presentation"><tbody><tr class="noresize"><td><span typeof="mw:File"><a href="/wiki/File:DNA_stub.png" class="mw-file-description"><img alt="Stub icon" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/61/DNA_stub.png/40px-DNA_stub.png" decoding="async" width="40" height="30" class="mw-file-element" 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