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itemtype="http://schema.org/ListItem"> <a href="/c/impurities/7" class="badge-wrapper bullet" itemprop="item"> <span class='badge-category-bg' style='background-color: #0088CC'></span> <span class='badge-category clear-badge'> <span class='category-name' itemprop='name'>N-nitrosamines Chemistry</span> </span> </a> <meta itemprop="position" content="1" /> </span> </div> </div> <div itemscope itemtype='http://schema.org/DiscussionForumPosting'> <meta itemprop='headline' content='Phenyl Morpholine'> <link itemprop='url' href='https://nitrosamines.usp.org/t/phenyl-morpholine/12759'> <meta itemprop='datePublished' content='2025-03-13T16:26:16Z'> <meta itemprop='articleSection' content='N-nitrosamines Chemistry'> <meta itemprop='keywords' content=''> <div itemprop='publisher' itemscope itemtype="http://schema.org/Organization"> <meta itemprop='name' content='United State Pharmacopeia'> <div itemprop='logo' itemscope itemtype="http://schema.org/ImageObject"> <meta itemprop='url' content='https://nitrosamines.usp.org/uploads/db7259/original/1X/245b8254540e755a018d20f2ffa64946d05afb63.svg'> </div> </div> <div id='post_1' class='topic-body crawler-post'> <div class='crawler-post-meta'> <span class="creator" itemprop="author" itemscope itemtype="http://schema.org/Person"> <a itemprop="url" rel='nofollow' href='https://nitrosamines.usp.org/u/wamis8182'><span itemprop='name'>wamis8182</span></a> </span> <link itemprop="mainEntityOfPage" href="https://nitrosamines.usp.org/t/phenyl-morpholine/12759"> <link itemprop="image" href="https://nitrosamines.usp.org/uploads/db7259/original/2X/3/3c377b16f24c9145dd5b38c455f054e9b210f6f9.png"> <span class="crawler-post-infos"> <time datetime='2025-03-13T16:26:16Z' class='post-time'> March 13, 2025, 4:26pm </time> <meta itemprop='dateModified' content='2025-03-13T16:26:16Z'> <span itemprop='position'>1</span> </span> </div> <div class='post' itemprop='text'> <p><div class="lightbox-wrapper"><a class="lightbox" href="https://nitrosamines.usp.org/uploads/db7259/original/2X/3/3c377b16f24c9145dd5b38c455f054e9b210f6f9.png" data-download-href="https://nitrosamines.usp.org/uploads/db7259/3c377b16f24c9145dd5b38c455f054e9b210f6f9" title="image"><img src="https://nitrosamines.usp.org/uploads/db7259/original/2X/3/3c377b16f24c9145dd5b38c455f054e9b210f6f9.png" alt="image" data-base62-sha1="8AHvWWksqz2PpsbyILWKXPKwMJj" width="195" height="191"><div class="meta"><svg class="fa d-icon d-icon-far-image svg-icon" aria-hidden="true"><use href="#far-image"></use></svg><span class="filename">image</span><span class="informations">195×191 3.03 KB</span><svg class="fa d-icon d-icon-discourse-expand svg-icon" aria-hidden="true"><use href="#discourse-expand"></use></svg></div></a></div></p> <p>Can the bond between Morpholine and Benzene be broken and hence morpholine nitrosated to N-nitroso Morpholine?</p> </div> <div itemprop="interactionStatistic" itemscope itemtype="http://schema.org/InteractionCounter"> <meta itemprop="interactionType" content="http://schema.org/LikeAction"/> <meta itemprop="userInteractionCount" content="0" /> <span class='post-likes'></span> </div> </div> <div id='post_2' itemprop='comment' itemscope itemtype='http://schema.org/Comment' class='topic-body crawler-post'> <div class='crawler-post-meta'> <span class="creator" itemprop="author" itemscope itemtype="http://schema.org/Person"> <a itemprop="url" rel='nofollow' href='https://nitrosamines.usp.org/u/JavierFernandez'><span itemprop='name'>JavierFernandez</span></a> </span> <span class="crawler-post-infos"> <time itemprop='datePublished' datetime='2025-03-14T11:37:36Z' class='post-time'> March 14, 2025, 11:37am </time> <meta itemprop='dateModified' content='2025-03-14T11:37:36Z'> <span itemprop='position'>2</span> </span> </div> <div class='post' itemprop='text'> <p>I believe that the answer in this case is, in case of doubt, do a Nitrosation assay.<br> In my opinion, the risks comes more from phenylmorpholine containing certain amounts of morpholine as impurity which can be nitrosated rather than direct nitrosation of phenylmorpholine</p> </div> <div itemprop="interactionStatistic" itemscope itemtype="http://schema.org/InteractionCounter"> <meta itemprop="interactionType" content="http://schema.org/LikeAction"/> <meta itemprop="userInteractionCount" content="2" /> <span class='post-likes'>2 Likes</span> </div> </div> </div> </div> <footer class="container wrap"> <nav class='crawler-nav'> <ul> <li itemscope itemtype='http://schema.org/SiteNavigationElement'> <span itemprop='name'> <a href='/' itemprop="url">Home </a> </span> </li> <li itemscope itemtype='http://schema.org/SiteNavigationElement'> <span itemprop='name'> <a href='/categories' itemprop="url">Categories </a> </span> </li> <li itemscope itemtype='http://schema.org/SiteNavigationElement'> <span itemprop='name'> <a href='/guidelines' itemprop="url">Guidelines </a> </span> </li> <li itemscope 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