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<!DOCTYPE html> <html xmlns="http://www.w3.org/1999/xhtml" lang="en" xml:lang="en"> <head>  <script async src="https://www.googletagmanager.com/gtag/js?id=G-WVK41JBQ8K"></script> <script> window.dataLayer = window.dataLayer || []; function gtag(){dataLayer.push(arguments);} gtag('js', new Date()); gtag('config', 'G-WVK41JBQ8K'); </script> <meta http-equiv="Content-Type" content="text/html;charset=utf-8" /> <title>Treatment of Key Populations and Unique Situations - Hepatitis C Online</title>  <link href="https://fonts.googleapis.com/css?family=Open+Sans:400,400i,600,600i,700,700i&subset=latin-ext" rel="stylesheet"> <link rel="stylesheet" href="//cdn.hepatitisc.uw.edu/css/vendors.css?v=bmhjdmMtbWFzdGVyLWM4ODQzNjczLTIwMjQtMTEtMTMtMjA1NjI0Cg" type="text/css" media="screen,print" /> <link rel="stylesheet" href="//cdn.hepatitisc.uw.edu/css/dynamic.css.php?v=bmhjdmMtbWFzdGVyLWM4ODQzNjczLTIwMjQtMTEtMTMtMjA1NjI0Cg" type="text/css" media="screen,print" /> <link rel="stylesheet" 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src="//cdn.hepatitisc.uw.edu/scripts/min/vendors-min.js?v=bmhjdmMtbWFzdGVyLWM4ODQzNjczLTIwMjQtMTEtMTMtMjA1NjI0Cg"></script> <script type="text/javascript" src="//cdn.hepatitisc.uw.edu/scripts/min/scripts-min.js?v=bmhjdmMtbWFzdGVyLWM4ODQzNjczLTIwMjQtMTEtMTMtMjA1NjI0Cg"></script> <link rel="apple-touch-icon" sizes="180x180" href="//cdn.hepatitisc.uw.edu/css/images/ios/logo.png" /><meta name="theme-color" content="#4b5c84"> </head> <body class="site-nhcvc logged-out action-custom custom-id-46 custom-type-topical custom-access-public custom-theme-36 custom-self-study not-mobile use-questions"> <section id="header-components"><div id="header"><div class="inner"><a href="/process.php?action=home" id="logo">Hepatitis C Online</a></div></div><div class="nav-outer"><div class="level1-navigation"><div class="inner"><div class="custom-curriculums-title custom-curriculum-46 theme-36"><h2 class="title"><a href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations">Treatment of Key Populations and Unique Situations</a></h2></div><ul class="main-menu"><li class="section section-menu visible-mobile"><div class="link"><span class="menu-open glyphicon glyphicon-th" aria-hidden="true"></span><span class="menu-close glyphicon glyphicon-remove" aria-hidden="true"></span> <span class="hidden">Site Navigation</span></div></li><li class="section home-section"><a href="/" title="Hepatitis C Online" class=" link"></a></li><li class="section biology"><a href="/page/hcv/biology" class="link ">HCV <br />Biology</a></li><li class="section treatments nhcvc-medications has-submenu"><a href="/page/treatment/drugs" class=" link ">HCV <br />Medications<span class="submenu-trigger"></span></a><div class="submenu medications"><div class="description description-default">Listed in <strong>alphabetical</strong> order.</div><ul><li class="treatment treatment-7"><a href="/page/treatment/drugs/elbasvir-grazoprevir"><img class="drug-preview" src="//cdn.hepatitisc.uw.edu/css/images/drugs/7.png" alt="Elbasvir-Grazoprevir (Zepatier) Pill Preview" />Elbasvir-Grazoprevir <em>Zepatier</em></a></li><li class="treatment treatment-22"><a href="/page/treatment/drugs/glecaprevir-pibrentasvir"><img class="drug-preview" src="//cdn.hepatitisc.uw.edu/css/images/drugs/22.png" alt="Glecaprevir-Pibrentasvir (Mavyret) Pill Preview" />Glecaprevir-Pibrentasvir <em>Mavyret</em></a></li><li class="treatment treatment-11"><a href="/page/treatment/drugs/ledipasvir-sofosbuvir"><img class="drug-preview" src="//cdn.hepatitisc.uw.edu/css/images/drugs/11.png" alt="Ledipasvir-Sofosbuvir (Harvoni) Pill Preview" />Ledipasvir-Sofosbuvir <em>Harvoni</em></a></li><li class="treatment treatment-3"><a href="/page/treatment/drugs/ribavirin-drug"><img class="drug-preview" src="//cdn.hepatitisc.uw.edu/css/images/drugs/3.png" alt="Ribavirin (Copegus, Rebetol, Ribasphere) Pill Preview" />Ribavirin <em>Copegus, Rebetol, Ribasphere</em></a></li><li class="treatment treatment-1"><a href="/page/treatment/drugs/sofosbuvir-drug"><img class="drug-preview" src="//cdn.hepatitisc.uw.edu/css/images/drugs/1.png" alt="Sofosbuvir (Sovaldi) Pill Preview" />Sofosbuvir <em>Sovaldi</em></a></li><li class="treatment treatment-20"><a href="/page/treatment/drugs/epclusa"><img class="drug-preview" src="//cdn.hepatitisc.uw.edu/css/images/drugs/20.png" alt="Sofosbuvir-Velpatasvir (Epclusa) Pill Preview" />Sofosbuvir-Velpatasvir <em>Epclusa</em></a></li><li class="treatment treatment-21"><a href="/page/treatment/drugs/sofosbuvir-velpatasvir-voxilaprevir"><img class="drug-preview" src="//cdn.hepatitisc.uw.edu/css/images/drugs/21.png" alt="Sofosbuvir-Velpatasvir-Voxilaprevir (Vosevi) Pill Preview" />Sofosbuvir-Velpatasvir-Voxilaprevir <em>Vosevi</em></a></li></ul></div></li><li class="section modules active-trail has-submenu"><a href="/alternate" class="link active-trail">Course <br /> Modules<span class="submenu-trigger"></span></a><div class="submenu modules"><ul><li class="level1 level1-all "><a href="/alternate"><span class="caption">View all Course Modules</span></a></li><li class="level1 level1-31 has-subsubmenu"><a href="/go/screening-diagnosis"><span class="num">1</span><span class="caption">Screening and Diagnosis of Hepatitis C Infection</span><span class="submenu-trigger"></span></a><div class="subsubmenu custom"><a class="description" href="/custom/screening-diagnosis"><h3>Self-Study Module<span class="edition-tag edition-tag-4">4th Edition</span><span class="cme-tag cme-tag-available">CNE/CME Available</span></h3> Track your progress and receive CE credit</a><ul><li><a href="/custom/screening-diagnosis">Screening and Diagnosis: Self-Study <span class="cme-tag cme-tag-available">CNE/CME</span></a></li></ul><h4>Lessons</h4><ol><li class="level2 level2-108"><a href="/custom/screening-diagnosis/epidemiology-us"><span class="caption">HCV Epidemiology in the United States</span></a></li><li class="level2 level2-109"><a href="/custom/screening-diagnosis/recommendations-screening"><span class="caption">Recommendations for Hepatitis C Screening</span></a></li><li class="level2 level2-110"><a href="/custom/screening-diagnosis/diagnostic-testing"><span class="caption">Hepatitis C Diagnostic Testing</span></a></li><li class="level2 level2-111"><a href="/custom/screening-diagnosis/counseling-prevention"><span class="caption">Counseling for Prevention of HCV Transmission</span></a></li><li class="level2 level2-112"><a href="/custom/screening-diagnosis/acute-diagnosis"><span class="caption">Diagnosis of Acute HCV Infection</span></a></li></ol><ul><li><a href="/custom/screening-diagnosis/certificate">Certificate Requirements <span class="cme-tag cme-tag-available">CNE/CME</span></a></li></ul></div><div class="subsubmenu level2s"><a class="description" href="/go/screening-diagnosis"><h3>Quick Reference<span class="edition-tag edition-tag-4">4th Edition</span></h3> Rapidly access information in this module</a><ul><li><a href="/go/screening-diagnosis">Screening and Diagnosis of Hepatitis C Infection: Overview</a></li></ul><h4>Lessons</h4><ol><li class="level2 level2-153"><a href="/go/screening-diagnosis/epidemiology-us/core-concept/all"><span class="caption">HCV Epidemiology in the United States</span></a></li><li class="level2 level2-157"><a href="/go/screening-diagnosis/recommendations-screening/core-concept/all"><span class="caption">Recommendations for Hepatitis C Screening</span></a></li><li class="level2 level2-154"><a href="/go/screening-diagnosis/diagnostic-testing/core-concept/all"><span class="caption">Hepatitis C Diagnostic Testing</span></a></li><li class="level2 level2-155"><a href="/go/screening-diagnosis/counseling-prevention/core-concept/all"><span class="caption">Counseling for Prevention of HCV Transmission</span></a></li><li class="level2 level2-156"><a href="/go/screening-diagnosis/acute-diagnosis/core-concept/all"><span class="caption">Diagnosis of Acute HCV Infection</span></a></li></ol></div></li><li class="level1 level1-34 has-subsubmenu"><a href="/go/evaluation-staging-monitoring"><span class="num">2</span><span class="caption">Evaluation, Staging, and Monitoring of Chronic Hepatitis C</span><span class="submenu-trigger"></span></a><div class="subsubmenu custom"><a class="description" href="/custom/evaluation-staging-monitoring"><h3>Self-Study Module<span class="edition-tag edition-tag-4">4th Edition</span><span class="cme-tag cme-tag-available">CNE/CME Available</span></h3> Track your progress and receive CE credit</a><ul><li><a href="/custom/evaluation-staging-monitoring">Evaluation, Staging, and Monitoring: Self-Study <span class="cme-tag cme-tag-available">CNE/CME</span></a></li></ul><h4>Lessons</h4><ol><li class="level2 level2-124"><a href="/custom/evaluation-staging-monitoring/initial-evaluation-chronic"><span class="caption">Initial Evaluation of Persons with Chronic HCV</span></a></li><li class="level2 level2-125"><a href="/custom/evaluation-staging-monitoring/natural-history"><span class="caption">Natural History of HCV Infection</span></a></li><li class="level2 level2-126"><a href="/custom/evaluation-staging-monitoring/counseling-liver-health"><span class="caption">Counseling Persons with Chronic HCV Infection</span></a></li><li class="level2 level2-127"><a href="/custom/evaluation-staging-monitoring/evaluation-staging"><span class="caption">Evaluation and Staging of Liver Fibrosis</span></a></li><li class="level2 level2-128"><a href="/custom/evaluation-staging-monitoring/evaluation-prognosis-cirrhosis"><span class="caption">Evaluation and Prognosis of Persons with Cirrhosis</span></a></li><li class="level2 level2-129"><a href="/custom/evaluation-staging-monitoring/surveillance-hepatocellular-carcinoma"><span class="caption">Surveillance for Hepatocellular Carcinoma</span></a></li><li class="level2 level2-130"><a href="/custom/evaluation-staging-monitoring/extrahepatic-conditions"><span class="caption">Extrahepatic Conditions Related to HCV Infection</span></a></li></ol><ul><li><a href="/custom/evaluation-staging-monitoring/certificate">Certificate Requirements <span class="cme-tag cme-tag-available">CNE/CME</span></a></li></ul></div><div class="subsubmenu level2s"><a class="description" href="/go/evaluation-staging-monitoring"><h3>Quick Reference<span class="edition-tag edition-tag-4">4th Edition</span></h3> Rapidly access information in this module</a><ul><li><a href="/go/evaluation-staging-monitoring">Evaluation, Staging, and Monitoring of Chronic Hepatitis C: Overview</a></li></ul><h4>Lessons</h4><ol><li class="level2 level2-169"><a href="/go/evaluation-staging-monitoring/initial-evaluation-chronic/core-concept/all"><span class="caption">Initial Evaluation of Persons with Chronic HCV</span></a></li><li class="level2 level2-170"><a href="/go/evaluation-staging-monitoring/natural-history/core-concept/all"><span class="caption">Natural History of HCV Infection</span></a></li><li class="level2 level2-171"><a href="/go/evaluation-staging-monitoring/counseling-liver-health/core-concept/all"><span class="caption">Counseling Persons with Chronic HCV Infection</span></a></li><li class="level2 level2-172"><a href="/go/evaluation-staging-monitoring/evaluation-staging/core-concept/all"><span class="caption">Evaluation and Staging of Liver Fibrosis</span></a></li><li class="level2 level2-175"><a href="/go/evaluation-staging-monitoring/evaluation-prognosis-cirrhosis/core-concept/all"><span class="caption">Evaluation and Prognosis of Persons with Cirrhosis</span></a></li><li class="level2 level2-173"><a href="/go/evaluation-staging-monitoring/surveillance-hepatocellular-carcinoma/core-concept/all"><span class="caption">Surveillance for Hepatocellular Carcinoma</span></a></li><li class="level2 level2-174"><a href="/go/evaluation-staging-monitoring/extrahepatic-conditions/core-concept/all"><span class="caption">Extrahepatic Conditions Related to HCV Infection</span></a></li></ol></div></li><li class="level1 level1-33 has-subsubmenu"><a href="/go/management-cirrhosis-related-complications"><span class="num">3</span><span class="caption">Management of Cirrhosis-Related Complications</span><span class="submenu-trigger"></span></a><div class="subsubmenu custom"><a class="description" href="/custom/management-cirrhosis-related-complications"><h3>Self-Study Module<span class="edition-tag edition-tag-4">4th Edition</span><span class="cme-tag cme-tag-available">CNE/CME Available</span></h3> Track your progress and receive CE credit</a><ul><li><a href="/custom/management-cirrhosis-related-complications">Management of Cirrhosis-Related Complications: Self-Study <span class="cme-tag cme-tag-available">CNE/CME</span></a></li></ul><h4>Lessons</h4><ol><li class="level2 level2-119"><a href="/custom/management-cirrhosis-related-complications/ascites-diagnosis-management"><span class="caption">Diagnosis and Management of Ascites</span></a></li><li class="level2 level2-120"><a href="/custom/management-cirrhosis-related-complications/spontaneous-bacterial-peritonitis-recognition-management"><span class="caption">Recognition and Management of Spontaneous Bacterial Peritonitis</span></a></li><li class="level2 level2-121"><a href="/custom/management-cirrhosis-related-complications/varices-screening-prevention-bleeding"><span class="caption">Screening for Varices and Prevention of Bleeding</span></a></li><li class="level2 level2-122"><a href="/custom/management-cirrhosis-related-complications/hepatic-encephalopathy-diagnosis-management"><span class="caption">Diagnosis and Management of Hepatic Encephalopathy</span></a></li><li class="level2 level2-123"><a href="/custom/management-cirrhosis-related-complications/liver-transplantation-referral"><span class="caption">Referral for Liver Transplantation</span></a></li></ol><ul><li><a href="/custom/management-cirrhosis-related-complications/certificate">Certificate Requirements <span class="cme-tag cme-tag-available">CNE/CME</span></a></li></ul></div><div class="subsubmenu level2s"><a class="description" href="/go/management-cirrhosis-related-complications"><h3>Quick Reference<span class="edition-tag edition-tag-4">4th Edition</span></h3> Rapidly access information in this module</a><ul><li><a href="/go/management-cirrhosis-related-complications">Management of Cirrhosis-Related Complications: Overview</a></li></ul><h4>Lessons</h4><ol><li class="level2 level2-164"><a href="/go/management-cirrhosis-related-complications/ascites-diagnosis-management/core-concept/all"><span class="caption">Diagnosis and Management of Ascites</span></a></li><li class="level2 level2-165"><a href="/go/management-cirrhosis-related-complications/spontaneous-bacterial-peritonitis-recognition-management/core-concept/all"><span class="caption">Recognition and Management of Spontaneous Bacterial Peritonitis</span></a></li><li class="level2 level2-166"><a href="/go/management-cirrhosis-related-complications/varices-screening-prevention-bleeding/core-concept/all"><span class="caption">Screening for Varices and Prevention of Bleeding</span></a></li><li class="level2 level2-167"><a href="/go/management-cirrhosis-related-complications/hepatic-encephalopathy-diagnosis-management/core-concept/all"><span class="caption">Diagnosis and Management of Hepatic Encephalopathy</span></a></li><li class="level2 level2-168"><a href="/go/management-cirrhosis-related-complications/liver-transplantation-referral/core-concept/all"><span class="caption">Referral for Liver Transplantation</span></a></li></ol></div></li><li class="level1 level1-35 has-subsubmenu"><a href="/go/evaluation-treatment"><span class="num">4</span><span class="caption">Evaluation and Preparation for Hepatitis C Treatment</span><span class="submenu-trigger"></span></a><div class="subsubmenu custom"><a class="description" href="/custom/evaluation-treatment"><h3>Self-Study Module<span class="edition-tag edition-tag-4">4th Edition</span><span class="cme-tag cme-tag-available">CNE/CME Available</span></h3> Track your progress and receive CE credit</a><ul><li><a href="/custom/evaluation-treatment">Evaluation and Preparation for Treatment: Self-Study <span class="cme-tag cme-tag-available">CNE/CME</span></a></li></ul><h4>Lessons</h4><ol><li class="level2 level2-131"><a href="/custom/evaluation-treatment/treatment-goals-predicting-response"><span class="caption">Goals and Benefits with HCV Treatment</span></a></li><li class="level2 level2-132"><a href="/custom/evaluation-treatment/treatment-initiation-decision"><span class="caption">Making a Decision on When to Initiate HCV Therapy</span></a></li><li class="level2 level2-133"><a href="/custom/evaluation-treatment/addressing-structural-barriers-to-treatment"><span class="caption">Addressing Structural Barriers to HCV Treatment</span></a></li></ol><ul><li><a href="/custom/evaluation-treatment/certificate">Certificate Requirements <span class="cme-tag cme-tag-available">CNE/CME</span></a></li></ul></div><div class="subsubmenu level2s"><a class="description" href="/go/evaluation-treatment"><h3>Quick Reference<span class="edition-tag edition-tag-4">4th Edition</span></h3> Rapidly access information in this module</a><ul><li><a href="/go/evaluation-treatment">Evaluation and Preparation for Hepatitis C Treatment: Overview</a></li></ul><h4>Lessons</h4><ol><li class="level2 level2-176"><a href="/go/evaluation-treatment/treatment-goals-predicting-response/core-concept/all"><span class="caption">Goals and Benefits with HCV Treatment</span></a></li><li class="level2 level2-177"><a href="/go/evaluation-treatment/treatment-initiation-decision/core-concept/all"><span class="caption">Making a Decision on When to Initiate HCV Therapy</span></a></li><li class="level2 level2-178"><a href="/go/evaluation-treatment/addressing-structural-barriers-to-treatment/core-concept/all"><span class="caption">Addressing Structural Barriers to HCV Treatment</span></a></li></ol></div></li><li class="level1 level1-30 has-subsubmenu"><a href="/go/treatment-infection"><span class="num">5</span><span class="caption">Treatment of Hepatitis C Infection</span><span class="submenu-trigger"></span></a><div class="subsubmenu custom"><a class="description" href="/custom/treatment"><h3>Self-Study Module<span class="edition-tag edition-tag-4">4th Edition</span><span class="cme-tag cme-tag-available">CNE/CME Available</span></h3> Track your progress and receive CE credit</a><ul><li><a href="/custom/treatment">Treatment of HCV: Self-Study <span class="cme-tag cme-tag-available">CNE/CME</span></a></li></ul><h4>Lessons</h4><ol><li class="level2 level2-102"><a href="/custom/treatment/multi-genotype-treatment-new-lesson"><span class="caption">Simplified HCV Treatment for All HCV Genotypes</span></a></li><li class="level2 level2-103"><a href="/custom/treatment/retreatment-patients-prior-treatment-experience"><span class="caption">Retreatment of Patients with Prior HCV Treatment Experience</span></a></li><li class="level2 level2-101"><a href="/custom/treatment/monitoring"><span class="caption">Monitoring During and After HCV Treatment</span></a></li><li class="level2 level2-105"><a href="/custom/treatment/treatment-cirrhosis"><span class="caption">Treatment of HCV in Persons with Cirrhosis</span></a></li><li class="level2 level2-104"><a href="/custom/treatment/treatment-acute-infection"><span class="caption">Treatment of Acute HCV Infection</span></a></li></ol><ul><li><a href="/custom/treatment/certificate">Certificate Requirements <span class="cme-tag cme-tag-available">CNE/CME</span></a></li></ul></div><div class="subsubmenu level2s"><a class="description" href="/go/treatment-infection"><h3>Quick Reference<span class="edition-tag edition-tag-4">4th Edition</span></h3> Rapidly access information in this module</a><ul><li><a href="/go/treatment-infection">Treatment of Hepatitis C Infection: Overview</a></li></ul><h4>Lessons</h4><ol><li class="level2 level2-149"><a href="/go/treatment-infection/multi-genotype-treatment-new-lesson/core-concept/all"><span class="caption">Simplified HCV Treatment for All HCV Genotypes</span></a></li><li class="level2 level2-150"><a href="/go/treatment-infection/retreatment-patients-prior-treatment-experience/core-concept/all"><span class="caption">Retreatment of Patients with Prior HCV Treatment Experience</span></a></li><li class="level2 level2-143"><a href="/go/treatment-infection/monitoring/core-concept/all"><span class="caption">Monitoring During and After HCV Treatment</span></a></li><li class="level2 level2-152"><a href="/go/treatment-infection/treatment-cirrhosis/core-concept/all"><span class="caption">Treatment of HCV in Persons with Cirrhosis</span></a></li><li class="level2 level2-151"><a href="/go/treatment-infection/treatment-acute-infection/core-concept/all"><span class="caption">Treatment of Acute HCV Infection</span></a></li></ol></div></li><li class="level1 level1-32 has-subsubmenu"><a href="/go/key-populations-situations"><span class="num">6</span><span class="caption">Treatment of Key Populations and Unique Situations</span><span class="submenu-trigger"></span></a><div class="subsubmenu custom"><a class="description" href="/custom/key-populations-unique-situations"><h3>Self-Study Module<span class="edition-tag edition-tag-4">4th Edition</span><span class="cme-tag cme-tag-available">CNE/CME Available</span></h3> Track your progress and receive CE credit</a><ul><li><a href="/custom/key-populations-unique-situations">Treatment of Key Populations and Unique Situations: Self-Study <span class="cme-tag cme-tag-available">CNE/CME</span></a></li></ul><h4>Lessons</h4><ol><li class="level2 level2-113"><a href="/custom/key-populations-unique-situations/treatment-hiv-coinfection"><span class="caption">Treatment of HCV in Persons with HIV Coinfection</span></a></li><li class="level2 level2-114"><a href="/custom/key-populations-unique-situations/treament-renal-impairment"><span class="caption">Treatment of HCV in Persons with Renal Impairment</span></a></li><li class="level2 level2-115"><a href="/custom/key-populations-unique-situations/treatment-substance-use"><span class="caption">Treatment of HCV in Persons with Substance Use</span></a></li><li class="level2 level2-116"><a href="/custom/key-populations-unique-situations/treatment-corrections"><span class="caption">Treatment of HCV in a Correctional Setting</span></a></li><li class="level2 level2-117"><a href="/custom/key-populations-unique-situations/management-health-care-workers-potentially-exposed-to-hcv"><span class="caption">Management of Health Care Personnel Exposed to HCV</span></a></li><li class="level2 level2-118"><a href="/custom/key-populations-unique-situations/perinatal-hcv-transmission"><span class="caption">Perinatal HCV Transmission</span></a></li></ol><ul><li><a href="/custom/key-populations-unique-situations/certificate">Certificate Requirements <span class="cme-tag cme-tag-available">CNE/CME</span></a></li></ul></div><div class="subsubmenu level2s"><a class="description" href="/go/key-populations-situations"><h3>Quick Reference<span class="edition-tag edition-tag-4">4th Edition</span></h3> Rapidly access information in this module</a><ul><li><a href="/go/key-populations-situations">Treatment of Key Populations and Unique Situations: Overview</a></li></ul><h4>Lessons</h4><ol><li class="level2 level2-158"><a href="/go/key-populations-situations/treatment-hiv-coinfection/core-concept/all"><span class="caption">Treatment of HCV in Persons with HIV Coinfection</span></a></li><li class="level2 level2-159"><a href="/go/key-populations-situations/treament-renal-impairment/core-concept/all"><span class="caption">Treatment of HCV in Persons with Renal Impairment</span></a></li><li class="level2 level2-160"><a href="/go/key-populations-situations/treatment-substance-use/core-concept/all"><span class="caption">Treatment of HCV in Persons with Substance Use</span></a></li><li class="level2 level2-161"><a href="/go/key-populations-situations/treatment-corrections/core-concept/all"><span class="caption">Treatment of HCV in a Correctional Setting</span></a></li><li class="level2 level2-162"><a href="/go/key-populations-situations/management-health-care-workers-potentially-exposed-to-hcv/core-concept/all"><span class="caption">Management of Health Care Personnel Exposed to HCV</span></a></li><li class="level2 level2-163"><a href="/go/key-populations-situations/perinatal-hcv-transmission/core-concept/all"><span class="caption">Perinatal HCV Transmission</span></a></li></ol></div></li></ul></div></li><li class="section tools has-submenu"><a href="/page/clinical-calculators/apri" 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class="custom-curriculums-home theme-36"><div class="row"><div class="col-xs-12"> <ul class="nav nav-tabs"><li role="presentation" class="active"><a class="" href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations/overview/about">About the Module</a></li><li role="presentation" class=""><a class="" href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations/overview/requirements">Certificate Requirements</a></li><li role="presentation" class=""><a class="" href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations/overview/competencies">Core Competencies</a></li></ul> </div></div><div class="row section section-home-page"><div class="col-xs-12"><div class="custom-curriculums-overview theme-36"><div class="inner"><div class="organization-logo logo-cdc-agreement" title="Funded by Centers for Disease Control and Prevention Cooperative Agreement (CDC-RFA-PS21-2105)"></div><div class="organization-logo logo-uw" title="University of Washington"></div><div class="about-course"><h2 class="section-title section-about"><span class="glyphicon glyphicon-info-sign"></span> About Treatment of Key Populations and Unique Situations Self-Study Module</h2><br /><div class="level1s-intro"><div class="row"><div class="col-xs-12 col-sm-5"><div class="content"><div class="section-objectives"><h4 id="objectives" class="title">Core Competency</h4><div class="content"><p class="lead">Apply Evidence-Based HCV Treatment to Key Populations and in Unique Situations</p></div></div></div></div><div class="col-xs-12 col-sm-4"><div class="section-objectives"><h4 id="description" class="title">Target Audience</h4><div class="content">Designed for clinicians who manage key populations of persons living with HCV and/or complex HCV-related unique treatment issues. Material covered is at an advanced level.</div></div></div><div class="section-quick-ref col-xs-12 col-sm-3"><h4 id="quick-reference" class="title">Quick Reference</h4><div class="content">You can find all of the topics from this module in the openly accessible <p><a href="/go/key-populations-situations" style="color: rgb(19,149,186);"><strong>Treatment of Key Populations and Unique Situations Quick Reference <span class="glyphicon glyphicon-chevron-right"></span></strong></a><br /><em>No Sign In or Registration Required</em></div></div><div class="col-xs-12 col-sm-9 section section-edition"><h3 id="edition" class="title">4th Edition</h3><div class="content"><strong>This is a substantial revision of the original content.</strong></div></div><div class="col-xs-12"><div class="section section-ce-notices"><div class="page-content-page page-ce-notices section-"><div class="inner"><h3 class="title">Free CME/CNE/CE Notices</h1><div class="content"><p>This site provides continuing education for physicians (MDs), advanced registered nurse practitioners (ARNPs), physician assistants (PAs), nurses, and nurse-midwives.</p> <p>The continuing education activity on this site, including continuing education credit, is provided free of charge. Funding for the site was provided by a grant from the Centers for Disease Control and Prevention (CDC).</p> <h3>Professional Credit for HCV Self Study Modules</h3> <p>Each topic overview and module requires approximately 60 minutes to complete. To apply for continuing education credit:</p> <ol> <li>read the topic overview,</li> <li>complete the activities,</li> <li>correctly answer 80% of the CE questions on the quiz,</li> <li>select either CME or CNE (depending upon your discipline and the certificate you wish to receive),</li> <li>complete and submit the evaluation form,</li> <li>print your own certificate.</li> </ol> <p>Records of all your CE activity on this site can be viewed either on the CNE or CME sites under the header "CME Tracker & CME Certificates" or "CNE Tracker and CNE Certificates."</p> <p>You are welcome to take the self-assessment quizzes even if you do not need continuing education credit. You can submit your answers to track your progress without earning CE credit.</p> <hr /> <div class="panel panel-default"> <div class="panel-heading"> <h3 class="panel-title">Continuing Medical Education (CME) Notice</h3> </div> <div class="panel-body"> <p>This activity has been planned and implemented in accordance with the Essential Areas and Policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of the University of Alabama School of Medicine (UASOM) and the University of Washington (UW).  The UASOM is accredited by the ACCME to provide continuing medical education for physicians.    </p> <p>The University of Alabama School of Medicine designates this online enduring material for a maximum of 1.0 <em>AMA PRA Category 1 Credit(s)™</em>. Physicians should claim only the credit commensurate with the extent of their participation in the activity.</p> </div> <div class="panel-footer"> <p>If a lesson was successfully completed prior to January 1 of last year, please contact <a href="mailto:cme@uab.edu">cme@uab.edu</a> to request a certificate of completion.</p> </div> </div> <div class="panel panel-default"> <div class="panel-heading"> <h3 class="panel-title">Continuing Nursing Education (CNE) Notice</h3> </div> <div class="panel-body"> <p><strong>Advanced practice nurses, nurses, and other disciplines*</strong>: The number of contact hours to be awarded, including those that qualify for pharmacology CE for advanced practice nurses, is noted in each lesson.</p> <p>The <a href="https://cne.nursing.uw.edu/" target="_blank">University of Washington Continuing Nursing Education (UWCNE)</a> is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center’s Commission on Accreditation.</p> </div> <div class="panel-footer"> <p>*Other disciplines include (however are not limited to): Disease intervention specialists, social workers, case managers, counselors, dietitians, and psychologists. Continuing education (CE) contact hours are awarded (60 minutes = 1 contact hour). Please contact your licensing agency should you have any questions about the acceptability of the certificate.</p> </div> </div></div></div></div></div></div></div></div><div class="inner"></div></div></div></div></div></div></div></div></div><div class="custom-curriculums-pt theme-36"><div id="progress-tracker" class="progress-tracker-container progress-tracker-edition-4"><div class="inner"> <h2 class="title"><i class="glyph-tasks"></i>Self-Study Module Progress Tracker - 4th Edition </h2> <div class="table-wrapper"><table><td class="level1 header empty"></td><td class="level1 header"><a href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations/treatment-hiv-coinfection" title="Treatment of HCV in Persons with HIV Coinfection" class="cc_sections113"><span class="object-type object-type-cc_sections">Lesson 1</span><span class="object-title">HIV Coinfection</a><div class="data-content"><div class="section"><ul> <li>Explain the impact of HIV on the progression of liver fibrosis in persons with untreated chronic HCV</li> <li>Describe current HCV treatment approaches in persons with HIV coinfection</li> <li>Discuss HCV treatment responses in persons with HIV and HCV coinfection compared with responses in persons with HCV monoinfection</li> <li>Summarize recommendations for treating HIV in persons with HCV and HIV coinfection</li> <li>List key drug interactions between HCV direct-acting antivirals and HIV antiretroviral medications</li> </ul></div></div></td><td class="level1 header"><a href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations/treament-renal-impairment" title="Treatment of HCV in Persons with Renal Impairment" class="cc_sections114"><span class="object-type object-type-cc_sections">Lesson 2</span><span class="object-title">Renal Impairment</a><div class="data-content"><div class="section"><ul> <li>Explain the impact of HCV on renal disease</li> <li>Summarize the main findings from HCV treatment studies in people with renal disease</li> <li>Discuss dosing of direct-acting antiviral medications in persons with chronic renal disease</li> <li>Describe appropriate HCV treatment in persons prior to renal transplantaton</li> <li>Summarize HCV treatment recommendations in persons following renal transplantation</li> </ul></div></div></td><td class="level1 header"><a href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations/treatment-substance-use" title="Treatment of HCV in Persons with Substance Use" class="cc_sections115"><span class="object-type object-type-cc_sections">Lesson 3</span><span class="object-title">Persons with Substance Use</a><div class="data-content"><div class="section"><ul> <li>Discuss the prevalence of substance use among persons in the United States</li> <li>Describe HCV treatment responses in persons with substance use disorders compared with those who do not have substance use disorders</li> <li>Summarize HCV treatment eligibility in persons who have a past or current substance use disorder</li> <li>List support services and management strategies for persons with substance use disorders who have chronic HCV infection</li> <li>Explain the concept of HCV reinfection in persons who inject drugs</li> </ul></div></div></td><td class="level1 header"><a href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations/treatment-corrections" title="Treatment of HCV in a Correctional Setting" class="cc_sections116"><span class="object-type object-type-cc_sections">Lesson 4</span><span class="object-title">Correctional Setting</a><div class="data-content"><div class="section"><ul> <li>Describe HCV prevalence in the correctional setting</li> <li>Explain the difference between jails and prisons</li> <li>Summarize HCV screening recommendations in correctional settings</li> <li>State recommendations for HCV treatment eligibility in prisons</li> <li>Discuss HCV treatment approach in prisons</li> </ul></div></div></td><td class="level1 header"><a href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations/management-health-care-workers-potentially-exposed-to-hcv" title="Management of Health Care Personnel Exposed to HCV" class="cc_sections117"><span class="object-type object-type-cc_sections">Lesson 5</span><span class="object-title">Management of Health Care Personnel Exposed to HCV</a><div class="data-content"><div class="section"><ul> <li>List the definition of health care personnel</li> <li>Estimate the risk of HCV seroconversion after an occupational exposure to HCV that involves a needlestick injury</li> <li>Describe management of health care personnel exposed to HCV, based on type and nature of exposure</li> <li>Summarize monitoring and follow-up testing of health care personnel after occupational exposure to HCV</li> <li>Discuss the treatment approach for health care personnel who acquire HCV from an occupational exposure</li> </ul></div></div></td><td class="level1 header"><a href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations/perinatal-hcv-transmission" title="Perinatal HCV Transmission" class="cc_sections118"><span class="object-type object-type-cc_sections">Lesson 6</span><span class="object-title">Perinatal HCV Transmission</a><div class="data-content"><div class="section"><ul> <li>Describe the current guidelines for HCV screening in pregnant women</li> <li>Identify the risk of mother-to-child transmission of HCV and factors associated with increased risk of transmission</li> <li>Summarize the impact of HCV on pregnancy outcomes</li> <li>Describe interventions and/or prophylactic measures to reduce the risk of mother-to-child transmission of HCV</li> <li>List recommendations for HCV testing and management in infants born to mothers with HCV.</li> </ul></div></div></td><tr class="level2"><td class="level2 header">Topic 1</td><td class="level2 level1"><a href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations/treatment-hiv-coinfection/1" title="Background of HIV-HCV Coinfection" class="cc_section113"> </a><div class="data-content"></div></td><td class="level2 level1"><a href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations/treament-renal-impairment/1" title="Background" class="cc_section114"> </a><div class="data-content"></div></td><td class="level2 level1"><a href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations/treatment-substance-use/1" title="Background" class="cc_section115"> </a><div class="data-content"></div></td><td class="level2 level1"><a href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations/treatment-corrections/1" title="Epidemiology of HCV in Corrections" class="cc_section116"> </a><div class="data-content"></div></td><td class="level2 level1"><a href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations/management-health-care-workers-potentially-exposed-to-hcv/1" title="Background" class="cc_section117"> </a><div class="data-content"></div></td><td class="level2 level1"><a href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations/perinatal-hcv-transmission/1" title="Background" class="cc_section118"> </a><div class="data-content"></div></td></tr> <tr class="level2"><td class="level2 header">Topic 2</td><td class="level2 level1"><a href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations/treatment-hiv-coinfection/2" title="HCV Treatment Data in Persons with HIV Coinfection" class="cc_section113"> </a><div class="data-content"></div></td><td class="level2 level1"><a href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations/treament-renal-impairment/2" title="HCV Treatment Studies in Persons with CKD" class="cc_section114"> </a><div class="data-content"></div></td><td class="level2 level1"><a href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations/treatment-substance-use/2" title="Approach to HCV Treatment in Persons with Substance Use" class="cc_section115"> </a><div class="data-content"></div></td><td class="level2 level1"><a href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations/treatment-corrections/2" title="HCV Screening in Correctional Settings" class="cc_section116"> </a><div class="data-content"></div></td><td class="level2 level1"><a href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations/management-health-care-workers-potentially-exposed-to-hcv/2" title="Risk of HCV Following Occupational Exposure" class="cc_section117"> </a><div class="data-content"></div></td><td class="level2 level1"><a href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations/perinatal-hcv-transmission/2" title="HCV Screening During Pregnancy" class="cc_section118"> </a><div class="data-content"></div></td></tr> <tr class="level2"><td class="level2 header">Topic 3</td><td class="level2 level1"><a href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations/treatment-hiv-coinfection/3" title="Treatment of HCV in Persons with HIV Coinfection" class="cc_section113"> </a><div class="data-content"></div></td><td class="level2 level1"><a href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations/treament-renal-impairment/3" title="HCV Treatment in Persons with CKD" class="cc_section114"> </a><div class="data-content"></div></td><td class="level2 level1"><a href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations/treatment-substance-use/3" title="HCV Treatment in Persons with Opioid Use" class="cc_section115"> </a><div class="data-content"></div></td><td class="level2 level1"><a href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations/treatment-corrections/3" title="Management of HCV in Jails versus Prisons" class="cc_section116"> </a><div class="data-content"></div></td><td class="level2 level1"><a href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations/management-health-care-workers-potentially-exposed-to-hcv/3" title="Approach to Managing Occupational Exposures to HCV" class="cc_section117"> </a><div class="data-content"></div></td><td class="level2 level1"><a href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations/perinatal-hcv-transmission/3" title="Factors Associated with HCV Perinatal Transmission" class="cc_section118"> </a><div class="data-content"></div></td></tr> <tr class="level2"><td class="level2 header">Topic 4</td><td class="level2 level1"><a href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations/treatment-hiv-coinfection/4" title="Treatment of HIV in Persons with HCV Coinfection" class="cc_section113"> </a><div class="data-content"></div></td><td class="level2 level1"><a href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations/treament-renal-impairment/4" title="Treatment of HCV in Setting of Renal Transplantation" class="cc_section114"> </a><div class="data-content"></div></td><td class="level2 level1"><a href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations/treatment-substance-use/4" title="HCV Treatment in Persons with Stimulant Use" class="cc_section115"> </a><div class="data-content"></div></td><td class="level2 level1"><a href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations/treatment-corrections/4" title="HCV Treatment Eligibility in Corrections" class="cc_section116"> </a><div class="data-content"></div></td><td class="level2 level1"><a href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations/management-health-care-workers-potentially-exposed-to-hcv/4" title="Monitoring Health Care Personnel after Occupational Exposure" class="cc_section117"> </a><div class="data-content"></div></td><td class="level2 level1"><a href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations/perinatal-hcv-transmission/4" title="Impact of Chronic HCV Infection on Pregnancy" class="cc_section118"> </a><div class="data-content"></div></td></tr> <tr class="level2"><td class="level2 header">Topic 5</td><td class="level2 level1"><a href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations/treatment-hiv-coinfection/5" title="Drug Interactions with HIV-HCV Coinfection Treatment" class="cc_section113"> </a><div class="data-content"></div></td><td class="level2 level1"><a href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations/treament-renal-impairment/5" title="Summary Points" class="cc_section114"> </a><div class="data-content"></div></td><td class="level2 level1"><a href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations/treatment-substance-use/5" title="HCV Treatment in Persons who Consume Alcohol" class="cc_section115"> </a><div class="data-content"></div></td><td class="level2 level1"><a href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations/treatment-corrections/5" title="Providing HCV Treatment in Correctional Settings" class="cc_section116"> </a><div class="data-content"></div></td><td class="level2 level1"><a href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations/management-health-care-workers-potentially-exposed-to-hcv/5" title="Management of Persons who Seroconvert to HCV" class="cc_section117"> </a><div class="data-content"></div></td><td class="level2 level1"><a href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations/perinatal-hcv-transmission/5" title="Effect of Pregnancy on Chronic HCV" class="cc_section118"> </a><div class="data-content"></div></td></tr> <tr class="level2"><td class="level2 header">Topic 6</td><td class="level2 level1"><a href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations/treatment-hiv-coinfection/6" title="Summary Points" class="cc_section113"> </a><div class="data-content"></div></td><td class="level2 level1 empty"></td><td class="level2 level1"><a href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations/treatment-substance-use/6" title="HCV Treatment in Persons who Use Cannabis" class="cc_section115"> </a><div class="data-content"></div></td><td class="level2 level1"><a href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations/treatment-corrections/6" title="Ongoing Care after HCV Treatment" class="cc_section116"> </a><div class="data-content"></div></td><td class="level2 level1"><a href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations/management-health-care-workers-potentially-exposed-to-hcv/6" title="Summary Points" class="cc_section117"> </a><div class="data-content"></div></td><td class="level2 level1"><a href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations/perinatal-hcv-transmission/6" title="Interventions to Prevent Mother-to-Child Transmission of HCV" class="cc_section118"> </a><div class="data-content"></div></td></tr> <tr class="level2"><td class="level2 header">Topic 7</td><td class="level2 level1 empty"></td><td class="level2 level1 empty"></td><td class="level2 level1"><a href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations/treatment-substance-use/7" title="Summary Points" class="cc_section115"> </a><div class="data-content"></div></td><td class="level2 level1"><a href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations/treatment-corrections/7" title="Public Health Opportunity" class="cc_section116"> </a><div class="data-content"></div></td><td class="level2 level1 empty"></td><td class="level2 level1"><a href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations/perinatal-hcv-transmission/7" title="Safety of HCV Treatment During Pregnancy and Breastfeeding" class="cc_section118"> </a><div class="data-content"></div></td></tr> <tr class="level2"><td class="level2 header">Topic 8</td><td class="level2 level1 empty"></td><td class="level2 level1 empty"></td><td class="level2 level1 empty"></td><td class="level2 level1"><a href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations/treatment-corrections/8" title="Summary Points" class="cc_section116"> </a><div class="data-content"></div></td><td class="level2 level1 empty"></td><td class="level2 level1"><a href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations/perinatal-hcv-transmission/8" title="Monitoring of Pregnant Women with HCV" class="cc_section118"> </a><div class="data-content"></div></td></tr> <tr class="level2"><td class="level2 header">Topic 9</td><td class="level2 level1 empty"></td><td class="level2 level1 empty"></td><td class="level2 level1 empty"></td><td class="level2 level1 empty"></td><td class="level2 level1 empty"></td><td class="level2 level1"><a href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations/perinatal-hcv-transmission/9" title="Management of Infants and Children Born to Mothers with HCV Infection" class="cc_section118"> </a><div class="data-content"></div></td></tr> <tr class="level2"><td class="level2 header">Topic 10</td><td class="level2 level1 empty"></td><td class="level2 level1 empty"></td><td class="level2 level1 empty"></td><td class="level2 level1 empty"></td><td class="level2 level1 empty"></td><td class="level2 level1"><a href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations/perinatal-hcv-transmission/10" title="Summary Points" class="cc_section118"> </a><div class="data-content"></div></td></tr> <tr class="level2 level2-ce"><td class="level2 level2-ce header">CE Quiz</td><td class="level2 level1"><a href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations/treatment-hiv-coinfection/quiz" title="HIV Coinfection CE Quiz" class="cc_section113"> </a><div class="data-content"></div></td><td class="level2 level1"><a href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations/treament-renal-impairment/quiz" title="Renal Impairment CE Quiz" class="cc_section114"> </a><div class="data-content"></div></td><td class="level2 level1"><a href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations/treatment-substance-use/quiz" title="Persons with Substance Use CE Quiz" class="cc_section115"> </a><div class="data-content"></div></td><td class="level2 level1"><a href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations/treatment-corrections/quiz" title="Correctional Setting CE Quiz" class="cc_section116"> </a><div class="data-content"></div></td><td class="level2 level1"><a href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations/management-health-care-workers-potentially-exposed-to-hcv/quiz" title="Management of Health Care Personnel Exposed to HCV CE Quiz" class="cc_section117"> </a><div class="data-content"></div></td><td class="level2 level1"><a href="https://www.hepatitisC.uw.edu/custom/key-populations-unique-situations/perinatal-hcv-transmission/quiz" title="Perinatal HCV Transmission CE Quiz" class="cc_section118"> </a><div class="data-content"></div></td></tr></table></div></div></div><div id="progress-tracker" class="progress-tracker-container progress-tracker-edition-3"><div class="inner"> <h2 class="title"><i class="glyph-tasks"></i>Self-Study Module Progress Tracker - 3rd Edition </h2> <div class="alert alert-info"><strong>3rd Edition</strong>. 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