Publications - Calico

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2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div>  <div class="featuredCard__title"> <h4> <a href="https://www.calicolabs.com/publication/dietary-restriction-impacts-health-and-lifespan-of-genetically-diverse-mice/" target="_self"> Dietary restriction impacts health and lifespan of genetically diverse mice </a> </h4> </div>   <p class="featuredCard__authors t-body-large"> Andrea Di Francesco, Andrew G. Deighan, Lev Litichevskiy, Zhenghao Chen, Alison Luciano, Laura Robinson, Gaven Garland, Hannah Donato, Matthew Vincent, Will Schott… </p> </div>  <div class="featuredCard__buttons"> <div class="primary-button"> <a id="4282" class="btn btn__simple green " style="" href="https://www.calicolabs.com/publication/dietary-restriction-impacts-health-and-lifespan-of-genetically-diverse-mice/" target="_self">Learn More</a> </div> <div class="secondary-button"> <a id="4282" class="btn btn__simple green " style="" href="https://www.nature.com/articles/s41586-024-08026-3" target="_blank">Read Full Publication</a> </div> </div> </div>  </div> </div> </div> <div class="news_feed__publication_filter container__medium-small"> <div class="filters"> <span class="t-label-small filter__heading">Filter</span> <div class="filter desktop"> <div class="custom_select news_feed__custom_select order" data-filter="order"> <button class="custom_select__trigger"> Latest </button> <ul class="custom_select__options 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.677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 11.18.2024 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Immunity </span> </div> <a href="https://www.sciencedirect.com/science/article/pii/S107476132400493X" target="_self" class="t-list-label"> Targeting the aminopeptidase ERAP enhances antitumor immunity by disrupting the NKG2A-HLA-E inhibitory checkpoint </a> <p class="publication_item__authors"> Hsiao-Wei Tsao, Seth Anderson, Kenneth J. Finn, Jonathan J. Perera, Lomax F. Pass, Emily M. Schneider, Aiping Jiang, Rachel Fetterman, Cun Lan Chuong, Kaiya Kozuma, Marcia M. Stickler, Marc Creixell, Susan Klaeger, Kshiti Meera Phulphagar, Suzanna Rachimi, Eva K. Verzani, Niclas Olsson, Juan Dubrot, Matthew F. Pech, Whitney Silkworth, Sarah Kate Lane-Reticker, Peter M. Allen, Kyrellos Ibrahim, Nelson H. Knudsen, Andrew Y. Cheng, Adrienne H. Long, Hakimeh Ebrahimi-Nik, Sarah Y. Kim, Peter P. Du, Arvin Iracheta-Vellve, Emily J. Robitschek, Juliette S.M.T. Suermondt, Thomas G.R. Davis, Clara H. Wolfe, Trisha Atluri, Kira E. Olander, Jason S. Rush, Thomas B. Sundberg, Fiona E. McAllister, Jennifer G. Abelin, Ari Firestone, David Stokoe, Steven A. Carr, Fiona A. Harding, Kathleen B. Yates, and Robert T. Manguso </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.nature.com/articles/s41467-024-52538-5 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://www.nature.com/articles/s41467-024-52538-5 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.nature.com/articles/s41467-024-52538-5 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.nature.com/articles/s41467-024-52538-5 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 09.27.2024 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Nature Communications </span> </div> <a href="https://www.nature.com/articles/s41467-024-52538-5" target="_self" class="t-list-label"> Specific activation of the integrated stress response uncovers regulation of central carbon metabolism and lipid droplet biogenesis </a> <p class="publication_item__authors"> Katherine Labbé, Lauren LeBon, Bryan King, Ngoc Vu, Emily H. Stoops, Nina Ly, Austin E. Y. T. Lefebvre, Phillip Seitzer, Swathi Krishnan, Jin-Mi Heo, Bryson Bennett, and Carmela Sidrauski </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.nature.com/articles/s42004-024-01263-7 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://www.nature.com/articles/s42004-024-01263-7 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.nature.com/articles/s42004-024-01263-7 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.nature.com/articles/s42004-024-01263-7 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 08.16.2024 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Communications Chemistry </span> </div> <a href="https://www.nature.com/articles/s42004-024-01263-7" target="_self" class="t-list-label"> Mechanistic insights into a heterobifunctional degrader-induced PTPN2/N1 complex </a> <p class="publication_item__authors"> Qi Hao, Manoj K. Rathinaswamy, Kelly L. Klinge, Matthew Bratkowski, Amirhossein Mafi, Christina K. Baumgartner, Keith M. Hamel, Gesine K. Veits, Rinku Jain, Claudio Catalano, Mark Fitzgerald, Alexander W. Hird, Eunice Park, Harit U. Vora, James A. Henderson, Kenton Longenecker, Charles W. Hutchins, Wei Qiu, Giovanna Scapin, Qi Sun, Vincent S. Stoll, Chaohong Sun, Ping Li, Dan Eaton, David Stokoe, Stewart L. Fisher, Christopher G. Nasveschuk, Marcia Paddock, and Michael E. Kort </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://link.springer.com/article/10.1007/s11357-024-01201-4 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://link.springer.com/article/10.1007/s11357-024-01201-4 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://link.springer.com/article/10.1007/s11357-024-01201-4 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://link.springer.com/article/10.1007/s11357-024-01201-4 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 05.21.2024 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> GeroScience </span> </div> <a href="https://link.springer.com/article/10.1007/s11357-024-01201-4" target="_self" class="t-list-label"> Five years later, with double the demographic data, naked mole-rat mortality rates continue to defy Gompertzian laws by not increasing with age </a> <p class="publication_item__authors"> J. Graham Ruby, Megan Smith and Rochelle Buffenstein </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://pubs.acs.org/doi/10.1021/jacs.4c05571 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://pubs.acs.org/doi/10.1021/jacs.4c05571 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://pubs.acs.org/doi/10.1021/jacs.4c05571 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://pubs.acs.org/doi/10.1021/jacs.4c05571 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 05.21.2024 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> JACS </span> </div> <a href="https://pubs.acs.org/doi/10.1021/jacs.4c05571" target="_self" class="t-list-label"> Reversibly Reactive Affinity Selection–Mass Spectrometry Enables Identification of Covalent Peptide Binders </a> <p class="publication_item__authors"> Peiyuan Zhang, Xiyun Ye, John C. K. Wang, Hannah T. Baddock, Zena Jensvold, Ian T. Foe, Andrei Loas, Dan L. Eaton, Qi Hao, Aaron H. Nile and Bradley L. Pentelute </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.nature.com/articles/s41588-024-01755-1 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://www.nature.com/articles/s41588-024-01755-1 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.nature.com/articles/s41588-024-01755-1 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.nature.com/articles/s41588-024-01755-1 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 05.14.2024 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Nature Genetics </span> </div> <a href="https://www.nature.com/articles/s41588-024-01755-1" target="_self" class="t-list-label"> Analysis of somatic mutations in whole blood from 200,618 individuals identifies pervasive positive selection and novel drivers of clonal hematopoiesis </a> <p class="publication_item__authors"> Nicholas Bernstein, Michael Spencer Chapman, Kudzai Nyamondo, Zhenghao Chen, Nicholas Williams, Emily Mitchell, Peter J. Campbell, Robert L. Cohen and Jyoti Nangalia </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.nature.com/articles/s41467-024-47264-x "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://www.nature.com/articles/s41467-024-47264-x "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.nature.com/articles/s41467-024-47264-x "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.nature.com/articles/s41467-024-47264-x "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 04.11.2024 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Nature Communications </span> </div> <a href="https://www.nature.com/articles/s41467-024-47264-x" target="_self" class="t-list-label"> Evolution of T cells in the cancer-resistant naked mole-rat </a> <p class="publication_item__authors"> Tzuhua D. Lin, Nimrod D. Rubinstein, Nicole L. Fong, Megan Smith, Wendy Craft, Baby Martin-McNulty, Rebecca Perry, Martha A. Delaney, Margaret A. Roy and Rochelle Buffenstein </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://pubs.acs.org/doi/10.1021/jacsau.3c00650 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://pubs.acs.org/doi/10.1021/jacsau.3c00650 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://pubs.acs.org/doi/10.1021/jacsau.3c00650 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://pubs.acs.org/doi/10.1021/jacsau.3c00650 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 04.10.2024 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> JACS Au </span> </div> <a href="https://pubs.acs.org/doi/10.1021/jacsau.3c00650" target="_self" class="t-list-label"> Development of an α-Klotho Recognizing High-Affinity Peptide Probe from In-Solution Enrichment </a> <p class="publication_item__authors"> Peiyuan Zhang, Xiyun Ye, John C. K. Wang, Corey L. Smith, Silvino Sousa, Andrei Loas, Dan L. Eaton, Magdalena Preciado López and Bradley L. Pentelute </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.pnas.org/doi/10.1073/pnas.2320013121 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" 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0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.pnas.org/doi/10.1073/pnas.2320013121 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.pnas.org/doi/10.1073/pnas.2320013121 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 03.28.2024 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> PNAS </span> </div> <a href="https://www.pnas.org/doi/10.1073/pnas.2320013121" target="_self" class="t-list-label"> Substrate recruitment via eIF2γ enhances catalytic efficiency of a holophosphatase that terminates the integrated stress response </a> <p class="publication_item__authors"> Yahui Yan, Maithili Shetty, Heather P Harding, Ginto George, Alisa Zyryanova, Katherine Labbé, Amirhossein Mafi, Qi Hao, Carmela Sidrauski and David Ron </p> 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.677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 03.26.2024 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Diabetes </span> </div> <a href="https://diabetesjournals.org/diabetes/article/doi/10.2337/db23-1005/154397/Genetic-evidence-for-distinct-biological" target="_self" class="t-list-label"> Genetic evidence for distinct biological mechanisms that link adiposity to type 2 diabetes: towards precision medicine </a> <p class="publication_item__authors"> Angela Abraham, Madeleine Cule, Marjola Thanaj, Nicolas Basty, M. Amin Hashemloo, Elena P. Sorokin, Brandon Whitcher, Stephen Burgess, Jimmy D. Bell, Naveed Sattar, E. 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Sharon Negri, Madison Milan, Helen Shi, Zeke Reyff, Cade Ballard, Jennifer Ihuoma, Andrea Di Francesco, and Stefano Tarantini </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" 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K. Wang, Hannah T. Baddock, Amirhossein Mafi, Ian T. Foe, Matthew Bratkowski, Ting-Yu Lin, Zena D. Jensvold, Magdalena Preciado López, David Stokoe, Dan Eaton, Qi Hao and Aaron H. 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0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 02.26.2024 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Cancer Research Communications </span> </div> <a href="https://aacrjournals.org/cancerrescommun/article/4/2/540/734917/Inhibition-of-Aurora-Kinase-Induces-Endogenous" target="_self" class="t-list-label"> Inhibition of Aurora Kinase Induces Endogenous Retroelements to Induce a Type I/III IFN Response via RIG-I </a> <p class="publication_item__authors"> Lisa Choy, Stephen Norris, Xiumin Wu, Ganesh Kolumam, Ari Firestone, Jeffrey Settleman, David Stokoe </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> 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.677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 02.23.2024 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Nature Methods </span> </div> <a href="https://www.nature.com/articles/s41592-024-02196-8" target="_self" class="t-list-label"> Super-sectioning with multi-sheet reversible saturable optical fluorescence transitions (RESOLFT) microscopy </a> <p class="publication_item__authors"> Andreas Bodén, Dirk Ollech, Andrew G. York, Alfred Millett-Sikking and Ilaria Testa </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://onlinelibrary.wiley.com/doi/10.1111/cns.14600 "> <svg height="30" viewBox="0 0 30 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0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 02.15.2024 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> CNS Neuroscience & Therapeutics </span> </div> <a href="https://onlinelibrary.wiley.com/doi/10.1111/cns.14600" target="_self" class="t-list-label"> GDF15 is a dynamic biomarker of the integrated stress response in the central nervous system </a> <p class="publication_item__authors"> Jyoti Asundi, Chunlian Zhang, Diana Donnelly-Roberts, Josè Zavala Solorio, Malleswari Challagundla, Caitlin Connelly, Christina Boch, Jun Chen, Mario Richter, Mohammad Mehdi Maneshi, Andrew M. Swensen, Lauren Lebon, Raphael Schiffmann, Subhabrata Sanyal, Carmela Sidrauski, Ganesh Kolumam and Amos Baruch </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" 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7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 02.12.2024 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Scientific Reports </span> </div> <a href="https://www.nature.com/articles/s41598-024-53900-9" target="_self" class="t-list-label"> S-polarized light-sheets improve resolution and light-efficiency in oblique plane microscopy </a> <p class="publication_item__authors"> Jon-Richard Sommernes, Alfred Millett-Sikking and Florian Ströhl </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" 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1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.frontiersin.org/journals/physiology/articles/10.3389/fphys.2024.1288657/full "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 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4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 02.01.2024 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Frontiers in Physiology </span> </div> <a href="https://www.frontiersin.org/journals/physiology/articles/10.3389/fphys.2024.1288657/full" target="_self" class="t-list-label"> Precision MRI phenotyping of muscle volume and quality at a population scale </a> <p class="publication_item__authors"> Marjola Thanaj, Nicolas Basty, Brandon Whitcher, Elena P. Sorokin, Yi Liu, Ramprakash Srinivasan, Madeleine Cule, E. Louise Thomas and Jimmy D. Bell </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.sciencedirect.com/science/article/abs/pii/S0165027024000098?via%3Dihub "> <svg height="30" viewBox="0 0 30 30" 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3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.sciencedirect.com/science/article/abs/pii/S0165027024000098?via%3Dihub "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 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1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 01.30.2024 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Journal of Neuroscience Methods </span> </div> <a href="https://www.sciencedirect.com/science/article/abs/pii/S0165027024000098?via%3Dihub" target="_self" class="t-list-label"> A Personalized Semi-Automatic Sleep Spindle Detection (PSASD) Framework </a> <p class="publication_item__authors"> MohammadMehdi Kafashan, Gaurang Gupte, Paul Kang, Orlandrea Hyche, Anhthi Luong, G.V. Prateek, Yo-El S. Ju and Ben Julian A. Palanca </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://onlinelibrary.wiley.com/doi/10.1002/clt2.12326 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://onlinelibrary.wiley.com/doi/10.1002/clt2.12326 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://onlinelibrary.wiley.com/doi/10.1002/clt2.12326 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://onlinelibrary.wiley.com/doi/10.1002/clt2.12326 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 01.17.2024 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Clinical and Translational Allergy </span> </div> <a href="https://onlinelibrary.wiley.com/doi/10.1002/clt2.12326" target="_self" class="t-list-label"> Exploratory immunogenicity outcomes of peanut oral immunotherapy: Findings from the PALISADE trial </a> <p class="publication_item__authors"> Caroline Nilsson, Andrea Vereda, Magnus P. Borres, Mats Andersson, Eva Södergren, Magnus Rudengren, Alex Smith, Reyna J. Simon, Robert Ryan, Montserrat Fernández-Rivas, Daniel Adelman, Brian P. Vickery </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://bmcmedimaging.biomedcentral.com/articles/10.1186/s12880-023-01149-5 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://bmcmedimaging.biomedcentral.com/articles/10.1186/s12880-023-01149-5 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://bmcmedimaging.biomedcentral.com/articles/10.1186/s12880-023-01149-5 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://bmcmedimaging.biomedcentral.com/articles/10.1186/s12880-023-01149-5 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 01.09.2024 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> BMC Medical Imaging </span> </div> <a href="https://bmcmedimaging.biomedcentral.com/articles/10.1186/s12880-023-01149-5" target="_self" class="t-list-label"> Liver shape analysis using statistical parametric maps at population scale </a> <p class="publication_item__authors"> Marjola Thanaj, Nicolas Basty, Madeleine Cule, Elena P. Sorokin, Brandon Whitcher, Jimmy D. Bell and E. Louise Thomas </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-023-05612-6 "> <svg height="30" viewBox="0 0 30 30" 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3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-023-05612-6 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 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1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 01.02.2024 </span> <span class="post-type" data-slug="commentaries-reviews"> Commentaries & Reviews </span> <span class="journal"> BMC Bioinformatics </span> </div> <a href="https://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-023-05612-6" target="_self" class="t-list-label"> Graph embedding on mass spectrometry- and sequencing-based biomedical data </a> <p class="publication_item__authors"> Edwin Alvarez-Mamani, Reinhard Dechant, César A Beltran-Castañón, and Alfredo J Ibáñez </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.nature.com/articles/s41592-023-02120-6 "> <svg height="30" 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4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.nature.com/articles/s41592-023-02120-6 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 12.18.2023 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Nature Methods </span> </div> <a href="https://www.nature.com/articles/s41592-023-02120-6" target="_self" class="t-list-label"> A data analysis framework for combining multiple batches increases the power of isobaric proteomics experiments </a> <p class="publication_item__authors"> Jonathon J O’Brien, Anil Raj, Aleksandr Gaun, Adam Waite, Wenzhou Li, David G Hendrickson, Niclas Olsson and Fiona E McAllister </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://pubs.acs.org/doi/10.1021/acschembio.3c00538 "> <svg height="30" viewBox="0 0 30 30" width="30"><g 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0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://pubs.acs.org/doi/10.1021/acschembio.3c00538 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://pubs.acs.org/doi/10.1021/acschembio.3c00538 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 12.09.2023 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> ACS Chemical Biology </span> </div> <a href="https://pubs.acs.org/doi/10.1021/acschembio.3c00538" target="_self" class="t-list-label"> Electrophile Scanning Reveals Reactivity Hotspots for the Design of Covalent Peptide Binders </a> <p class="publication_item__authors"> Nathalie M Grob, Clint Remarcik, Simon L Rössler, Jeffrey Y K Wong, John C K Wang, Jason Tao, Corey L Smith, Andrei Loas, Stephen L Buchwald, Dan L Eaton, Magdalena Preciado López and Bradley L Pentelute </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://bmcnephrol.biomedcentral.com/articles/10.1186/s12882-023-03407-8 "> <svg 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1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://bmcnephrol.biomedcentral.com/articles/10.1186/s12882-023-03407-8 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 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2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 12.06.2023 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> BMC Nephrology </span> </div> <a href="https://bmcnephrol.biomedcentral.com/articles/10.1186/s12882-023-03407-8" target="_self" class="t-list-label"> Kidney shape statistical analysis: associations with disease and anthropometric factors </a> <p class="publication_item__authors"> Marjola Thanaj, Nicolas Basty, Madeleine Cule, Elena P. Sorokin, Brandon Whitcher, Ramprakash Srinivasan, Rachel Lennon, Jimmy D. Bell and E. Louise Thomas </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://onlinelibrary.wiley.com/doi/10.1002/yea.3910 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://onlinelibrary.wiley.com/doi/10.1002/yea.3910 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://onlinelibrary.wiley.com/doi/10.1002/yea.3910 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://onlinelibrary.wiley.com/doi/10.1002/yea.3910 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 11.23.2023 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Yeast </span> </div> <a href="https://onlinelibrary.wiley.com/doi/10.1002/yea.3910" target="_self" class="t-list-label"> Characterizing a panel of amino acid auxotrophs under auxotrophic starvation conditions </a> <p class="publication_item__authors"> Alisha G. Lewis, Laurin Carmichael, Rebecca Y. Wang and Patrick A. Gibney </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.nature.com/articles/s41467-023-43304-0 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://www.nature.com/articles/s41467-023-43304-0 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.nature.com/articles/s41467-023-43304-0 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.nature.com/articles/s41467-023-43304-0 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 11.16.2023 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Nature Communications </span> </div> <a href="https://www.nature.com/articles/s41467-023-43304-0" target="_self" class="t-list-label"> Glutamine metabolism inhibition has dual immunomodulatory and antibacterial activities against Mycobacterium tuberculosis </a> <p class="publication_item__authors"> Sadiya Parveen, Jessica Shen, Shichun Lun, Liang Zhao, Jesse Alt, Benjamin Koleske, Robert D. Leone, Rana Rais, Jonathan D. Powell, John R. Murphy, Barbara S. Slusher and William R. Bishai </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://journals.aai.org/jimmunol/article/211/12/1767/266440/SIKs-Regulate-HDAC7-Stabilization-and-Cytokine "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://journals.aai.org/jimmunol/article/211/12/1767/266440/SIKs-Regulate-HDAC7-Stabilization-and-Cytokine "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://journals.aai.org/jimmunol/article/211/12/1767/266440/SIKs-Regulate-HDAC7-Stabilization-and-Cytokine "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://journals.aai.org/jimmunol/article/211/12/1767/266440/SIKs-Regulate-HDAC7-Stabilization-and-Cytokine "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 11.10.2023 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Journal of Immunology </span> </div> <a href="https://journals.aai.org/jimmunol/article/211/12/1767/266440/SIKs-Regulate-HDAC7-Stabilization-and-Cytokine" target="_self" class="t-list-label"> SIKs Regulate HDAC7 Stabilization and Cytokine Recall in Late-Stage T Cell Effector Differentiation </a> <p class="publication_item__authors"> Rachel S Helms, Alberto Marin-Gonzalez, Chirag H Patel, Im-Hong Sun, Jiayu Wen, Robert D Leone, Bridget Duvall, Run-Duo Gao, Taekjip Ha, Takashi Tsukamoto, Barbara S Slusher, Joel L Pomerantz and Jonathan D Powell </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 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5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://insight.jci.org/articles/view/172977 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 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4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 11.07.2023 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> JCI Insight </span> </div> <a href="https://insight.jci.org/articles/view/172977" target="_self" class="t-list-label"> PGF2α signaling drives fibrotic remodeling and fibroblast population dynamics in mice </a> <p class="publication_item__authors"> Luis R. Rodriguez, Soon Yew Tang, Willy Roque Barboza, Aditi Murthy, Yaniv Tomer, Tian-Quan Cai, Swati Iyer, Katrina Chavez, Ujjalkumar Subhash Das, Soumita Ghosh, Charlotte H. Cooper, Thalia T. Dimopoulos, Apoorva Babu, Caitlin Connelly, Garret A. FitzGerald and Michael F. Beers </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.nature.com/articles/s42004-023-01032-y "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://www.nature.com/articles/s42004-023-01032-y "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.nature.com/articles/s42004-023-01032-y "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.nature.com/articles/s42004-023-01032-y "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 10.28.2023 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Communications Chemistry </span> </div> <a href="https://www.nature.com/articles/s42004-023-01032-y" target="_self" class="t-list-label"> Cryo-EM structure of human PAPP-A2 and mechanism of substrate recognition </a> <p class="publication_item__authors"> Janani Sridar, Amirhossein Mafi, Russell A. Judge, Jun Xu, Kailyn A. Kong, John C. K. Wang, Vincent S. Stoll, Georgios Koukos, Reyna J. Simon, Dan Eaton, Matthew Bratkowski, Qi Hao </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://pubs.rsc.org/en/content/articlelanding/2023/sc/d3sc02782a "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://pubs.rsc.org/en/content/articlelanding/2023/sc/d3sc02782a "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://pubs.rsc.org/en/content/articlelanding/2023/sc/d3sc02782a "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://pubs.rsc.org/en/content/articlelanding/2023/sc/d3sc02782a "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 10.25.2023 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Chemical Science </span> </div> <a href="https://pubs.rsc.org/en/content/articlelanding/2023/sc/d3sc02782a" target="_self" class="t-list-label"> Discovery of reactive peptide inhibitors of human papillomavirus oncoprotein E6 </a> <p class="publication_item__authors"> Xiyun Ye, Peiyuan Zhang, Jason Tao, John C. K. Wang, Amirhossein Mafi, Nathalie M. Grob, Anthony J. Quartararo, Hannah T. Baddock, Leanne J. G. Chan, Fiona E. McAllister, Ian Foe, Andrei Loas, Dan L. Eaton, Qi Hao, Aaron H. Nile, Bradley L. Pentelute </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.nature.com/articles/s41586-023-06575-7 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://www.nature.com/articles/s41586-023-06575-7 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.nature.com/articles/s41586-023-06575-7 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.nature.com/articles/s41586-023-06575-7 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 10.04.2023 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Nature </span> </div> <a href="https://www.nature.com/articles/s41586-023-06575-7" target="_self" class="t-list-label"> The PTPN2/PTPN1 inhibitor ABBV-CLS-484 unleashes potent anti-tumour immunity </a> <p class="publication_item__authors"> Christina K. Baumgartner, Hakimeh Ebrahimi-Nik, Arvin Iracheta-Vellve, Keith M. Hamel, Kira E. Olander, Thomas G. R. Davis, Kathleen A. McGuire, Geoff T. Halvorsen, Omar I. Avila, Chirag H. Patel, Sarah Y. Kim, Ashwin V. Kammula, Audrey J. Muscato, Kyle Halliwill, Prasanthi Geda, Kelly L. Klinge, Zhaoming Xiong, Ryan Duggan, Liang Mu, Mitchell D. Yeary, James C. Patti, Tyler M. Balon, Rebecca Mathew, Carey Backus, Domenick E. Kennedy, Angeline Chen, Kenton Longenecker, Joseph T. Klahn, Cara L. Hrusch, Navasona Krishnan, Charles W. Hutchins, Jax P. Dunning, Marinka Bulic, Payal Tiwari, Kayla J. Colvin, Cun Lan Chuong, Ian C. Kohnle, Matthew G. Rees, Andrew Boghossian, Melissa Ronan, Jennifer A. Roth, Meng-Ju Wu, Juliette S. M. T. Suermondt, Nelson H. Knudsen, Collins K. Cheruiyot, Debattama R. Sen, Gabriel K. Griffin, Todd R. Golub, Nabeel El-Bardeesy, Joshua H. Decker, Yi Yang, Magali Guffroy, Stacey Fossey, Patricia Trusk, Im-Meng Sun, Yue Liu, Wei Qiu, Qi Sun, Marcia N. Paddock, Elliot P. Farney, Mark A. Matulenko, Clay Beauregard, Jennifer M. Frost, Kathleen B. Yates, Philip R. Kym, Robert T. Manguso </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.nature.com/articles/s41586-023-06592-6 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://www.nature.com/articles/s41586-023-06592-6 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.nature.com/articles/s41586-023-06592-6 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.nature.com/articles/s41586-023-06592-6 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 10.04.2023 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Nature </span> </div> <a href="https://www.nature.com/articles/s41586-023-06592-6" target="_self" class="t-list-label"> Plasma proteomic associations with genetics and health in the UK Biobank </a> <p class="publication_item__authors"> Benjamin B. Sun, Joshua Chiou, Matthew Traylor, Christian Benner, Yi-Hsiang Hsu, Tom G. Richardson, Praveen Surendran, Anubha Mahajan, Chloe Robins, Steven G. Vasquez-Grinnell, Liping Hou, Erika M. Kvikstad,Oliver S. Burren, Jonathan Davitte, Kyle L. Ferber, Christopher E. Gillies, Åsa K. Hedman, Sile Hu, inchi Lin, Rajesh Mikkilineni, Rion K. Pendergrass, Corran Pickering, Bram Prins, Denis Baird, Chia-Yen Chen, Lucas D. Ward, Aimee M. Deaton, Samantha Welsh, Carissa M. Willis, Nick Lehner, Matthias Arnold, Maria A. Wörheide, Karsten Suhre, Gabi Kastenmüller, Anurag Sethi, Madeleine Cule, Anil Raj, Alnylam Human Genetics, AstraZeneca Genomics Initiative, Biogen Biobank Team, Bristol Myers Squibb, Genentech Human Genetics, GlaxoSmithKline Genomic Sciences, Pfizer Integrative Biology, Population Analytics of Janssen Data Sciences, Regeneron Genetics Center, Lucy Burkitt-Gray, Eugene Melamud, Mary Helen Black, Eric B. Fauman, Joanna M. M. Howson, Hyun Min Kang, Mark I. McCarthy, Paul Nioi, Slavé Petrovski, Robert A. Scott, Erin N. Smith, Sándor Szalma, Dawn M. Waterworth, Lyndon J. Mitnaul, Joseph D. Szustakowski, Bradford W. Gibson, Melissa R. Miller and Christopher D. Whelan </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.nature.com/articles/s42255-023-00872-1 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://www.nature.com/articles/s42255-023-00872-1 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.nature.com/articles/s42255-023-00872-1 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.nature.com/articles/s42255-023-00872-1 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 08.28.2023 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Nature Metabolism </span> </div> <a href="https://www.nature.com/articles/s42255-023-00872-1" target="_self" class="t-list-label"> Cell cycle-linked vacuolar pH dynamics regulate amino acid homeostasis and cell growth </a> <p class="publication_item__authors"> Voytek Okreglak, Rachel Ling, Maria Ingaramo, Nathaniel H. Thayer, Alfred Millett-Sikking and Daniel E. Gottschling </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.nature.com/articles/s41598-023-40738-w "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://www.nature.com/articles/s41598-023-40738-w "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.nature.com/articles/s41598-023-40738-w "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.nature.com/articles/s41598-023-40738-w "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 08.21.2023 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Scientific Report </span> </div> <a href="https://www.nature.com/articles/s41598-023-40738-w" target="_self" class="t-list-label"> 3D mouse pose from single-view video and a new dataset </a> <p class="publication_item__authors"> Bo Hu, Bryan Seybold, Shan Yang, Avneesh Sud, Yi Liu, Karla Barron, Paulyn Cha, Marcelo Cosino, Ellie Karlsson, Janessa Kite, Ganesh Kolumam, Joseph Preciado, José Zavala-Solorio, Chunlian Zhang, Xiaomeng Zhang, Martin Voorbach, Ann E. Tovcimak, J. Graham Ruby & David A. Ross </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.cell.com/cell-reports/fulltext/S2211-1247(23)00913-0#%20 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://www.cell.com/cell-reports/fulltext/S2211-1247(23)00913-0#%20 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.cell.com/cell-reports/fulltext/S2211-1247(23)00913-0#%20 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 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1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 08.01.2023 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Cell Report </span> </div> <a href="https://www.cell.com/cell-reports/fulltext/S2211-1247(23)00913-0#%20" target="_self" class="t-list-label"> Individual cell types in C. elegans age differently and activate distinct cell-protective responses </a> <p class="publication_item__authors"> Antoine Emile Roux, Han Yuan, Katie Podshivalova, David Hendrickson, Rex Kerr, Cynthia Kenyon, David Kelley </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.aging-us.com/article/204796/text "> <svg 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3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.aging-us.com/article/204796/text "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 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0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 06.13.2023 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Aging </span> </div> <a href="https://www.aging-us.com/article/204796/text" target="_self" class="t-list-label"> LAMP2A, and other chaperone-mediated autophagy related proteins, do not decline with age in genetically heterogeneous UM-HET3 mice </a> <p class="publication_item__authors"> Katherine K. Zhang, Peichuan Zhang, Anagha Kodur, Ilkim Erturk, Calvin M. Burns, Cynthia Kenyon, Richard A. Miller and S. Joseph Endicott </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.life-science-alliance.org/content/6/8/e202201869 "> <svg height="30" viewBox="0 0 30 30" width="30"><g 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0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 06.13.2023 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Life Science Alliance </span> </div> <a href="https://www.life-science-alliance.org/content/6/8/e202201869" target="_self" class="t-list-label"> An immune-based tool platform for in vivo cell clearance </a> <p class="publication_item__authors"> Jieqiong Zhang, Tatsuya Tsukui, Xiumin Wu, Alyssa Brito, John Maxwell Trumble, Juan C Caraballo, Greg M Allen, José Zavala-Solorio, Chunlian Zhang, Jonathan Paw, Wendell A Lim, Jiefei Geng, Yuliya Kutskova, Adam Freund, Ganesh Kolumam, Dean Sheppard and Robert L Cohen </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" 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12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.science.org/doi/10.1126/sciadv.adg5702?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 05.26.2023 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Science Advances </span> </div> <a href="https://www.science.org/doi/10.1126/sciadv.adg5702?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed" target="_self" class="t-list-label"> Global analysis of the yeast knockout phenome </a> <p class="publication_item__authors"> Gina Turco, Christie Chang, Rebecca Y Wang, Griffin Kim, Emily H Stoops, Brianna Richardson, Vanessa Sochat, Jennifer Rust, Rose Oughtred, Nathaniel Thayer, Fan Kang, Michael S Livstone, Sven Heinicke, Mark Schroeder, Kara J Dolinski, David Botstein and Anastasia Baryshnikova </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" 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0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 05.24.2023 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> BMC Bioinformatics </span> </div> <a href="https://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-023-05343-8" target="_self" class="t-list-label"> Drug mechanism enrichment analysis improves prioritization of therapeutics for repurposing </a> <p class="publication_item__authors"> Belinda B Garana, James H Joly, Alireza Delfarah, Hyunjun Hong and Nicholas A Graham </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" 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stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 05.08.2023 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Nature Communications </span> </div> <a href="https://www.nature.com/articles/s41467-023-38279-x" target="_self" class="t-list-label"> Genetics implicates overactive osteogenesis in the development of diffuse idiopathic skeletal hyperostosis </a> <p class="publication_item__authors"> Anurag Sethi, J. Graham Ruby, Matthew A. Veras, Natalie Telis & Eugene Melamud </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://onlinelibrary.wiley.com/doi/10.1002/anie.202300289 "> <svg height="30" viewBox="0 0 30 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0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://onlinelibrary.wiley.com/doi/10.1002/anie.202300289 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 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0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 05.02.2023 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Angewandte Chem </span> </div> <a href="https://onlinelibrary.wiley.com/doi/10.1002/anie.202300289" target="_self" class="t-list-label"> Branched Multimeric Peptides as Affinity Reagents for the Detection of α-Klotho Protein </a> <p class="publication_item__authors"> Xiyun Ye, Peiyuan Zhang, John C K Wang, Corey L Smith, Silvino Sousa, Andrei Loas, Dan L Eaton, Magdalena Preciado López and Bradley L Pentelute </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0283506 "> <svg height="30" viewBox="0 0 30 30" 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3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0283506 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 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1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 04.13.2023 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> PLOS One </span> </div> <a href="https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0283506" target="_self" class="t-list-label"> Abdominal imaging associates body composition with COVID-19 severity </a> <p class="publication_item__authors"> Nicolas Basty, Elena P. Sorokin, Marjola Thanaj, Ramprakash Srinivasan, Brandon Whitcher, Jimmy D. Bell, Madeleine Cule and E. Louise Thomas </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.science.org/doi/10.1126/science.abm3452 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://www.science.org/doi/10.1126/science.abm3452 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.science.org/doi/10.1126/science.abm3452 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.science.org/doi/10.1126/science.abm3452 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 03.09.2023 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Science </span> </div> <a href="https://www.science.org/doi/10.1126/science.abm3452" target="_self" class="t-list-label"> Protein-metabolite interactomics of carbohydrate metabolism reveal regulation of lactate dehydrogenase </a> <p class="publication_item__authors"> Kevin G. Hicks, Ahmad A. Cluntun, Heidi L. Schubert, Sean R. Hackett, Jordan A. Berg, Paul G. Leonard, Mariana A. Ajalla Aleixo, Youjia Zhou, Alex J. Bott, Sonia R. Salvatore, Fei Chang, Aubrie Blevins, Paige Barta, Samantha Tilley, Aaron Leifer, Andrea Guzman, Ajak Arok, Sarah Fogarty, Jacob M. Winter, Hee-Chul Ahn, Karen N. Allen, Samual Block, Iara A. Cardoso, Jianping Ding, Ingrid Dreveny, William C. Gasper, Quinn Ho, Atsushi Matsuura, Michael J. Palladino, Sabin Prajapati, Pengkai Sun, Kai Tittmann, Dean R. Tolan, Judith Unterlass, Andrew P. Vandemark, Matthew G. Vander Heiden, Bradley A. Webb, Cai-Hong Yun, Pengkai Zhao, Bei Wang, Francisco J. Schopfer, Christopher P. Hill, Maria Cristina Nonato, Florian L. Muller, James E. Cox, Jared Rutter </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://pubs.acs.org/doi/10.1021/acs.jmedchem.2c01415 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://pubs.acs.org/doi/10.1021/acs.jmedchem.2c01415 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://pubs.acs.org/doi/10.1021/acs.jmedchem.2c01415 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://pubs.acs.org/doi/10.1021/acs.jmedchem.2c01415 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 03.06.2023 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Journal of Medicinal Chemistry </span> </div> <a href="https://pubs.acs.org/doi/10.1021/acs.jmedchem.2c01415" target="_self" class="t-list-label"> Discovery of a Potent Chloroacetamide GPX4 Inhibitor with Bioavailability to Enable Target Engagement in Mice, a Potential Tool Compound for Inducing Ferroptosis In Vivo </a> <p class="publication_item__authors"> John T. Randolph, Matthew J. O’Connor, Fei Han, Charles W. Hutchins, Y. Amy Siu, Min Cho, Yunan Zheng, Jonathan A. Hickson, Jana L. Markley, Vlasios Manaves, Mikkel Algire, Kenton A. Baker, Alex M. Chapman, Sujatha M. Gopalakrishnan, Sanjay C. Panchal, Kelly Foster-Duke, DeAnne F. Stolarik, Anita Kempf-Grote, Darby Dammeier, Stacey Fossey, Qi Sun, Chaohong Sun, Yu Shen, Michael J. Dart, Warren M. Kati, Albert Lai, Ari J. Firestone and Michael E. Kort </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://link.springer.com/protocol/10.1007/978-1-0716-2978-9_5 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://link.springer.com/protocol/10.1007/978-1-0716-2978-9_5 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://link.springer.com/protocol/10.1007/978-1-0716-2978-9_5 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://link.springer.com/protocol/10.1007/978-1-0716-2978-9_5 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 02.12.2023 </span> <span class="post-type" data-slug="commentaries-reviews"> Commentaries & Reviews </span> <span class="journal"> Methods in Molecular Biology </span> </div> <a href="https://link.springer.com/protocol/10.1007/978-1-0716-2978-9_5" target="_self" class="t-list-label"> High-Throughput Proteome Profiling of Plasma and Native Plasma Complexes Using Native Chromatography </a> <p class="publication_item__authors"> Aleksandr Gaun, Niclas Olsson, John C. K. Wang, Dan L. Eaton and Fiona E. McAllister </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://aacrjournals.org/cancerdiscovery/article/13/2/432/716311/Senescence-Rewires-Microenvironment-Sensing-to "> <svg 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1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://aacrjournals.org/cancerdiscovery/article/13/2/432/716311/Senescence-Rewires-Microenvironment-Sensing-to "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 02.06.2023 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Cancer Discovery </span> </div> <a href="https://aacrjournals.org/cancerdiscovery/article/13/2/432/716311/Senescence-Rewires-Microenvironment-Sensing-to" target="_self" class="t-list-label"> Senescence Rewires Microenvironment Sensing to Facilitate Antitumor Immunity </a> <p class="publication_item__authors"> Hsuan-An Chen, Yu-Jui Ho, Riccardo Mezzadra, Jose M Adrover, Ryan Smolkin, Changyu Zhu, Katharina Woess, Nicholas Bernstein, Georgia Schmitt, Linda Fong, Wei Luan, Alexandra Wuest, Sha Tian, Xiang Li, Caroline Broderick, Ronald C Hendrickson, Mikala Egeblad, Zhenghao Chen, Direna Alonso-Curbelo and Scott W Lowe </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.nature.com/articles/s41586-022-05602-3 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://www.nature.com/articles/s41586-022-05602-3 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle 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fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.nature.com/articles/s41586-022-05602-3 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 02.01.2023 </span> <span class="post-type" data-slug="commentaries-reviews"> Commentaries & Reviews </span> <span class="journal"> Nature </span> </div> <a href="https://www.nature.com/articles/s41586-022-05602-3" target="_self" class="t-list-label"> GOT1 constrains TH17 cell differentiation, while promoting iTreg cell differentiation </a> <p class="publication_item__authors"> Wei Xu, Chirag H. Patel, Jesse Alt, Liang Zhao, Im-Hong Sun, Min-Hee Oh, Im-Meng Sun, Jiayu Wen, Richard L. Blosser, Ada J. Tam and Jonathan D. Powell </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" 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class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 01.27.2023 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> The Journals of Gerontology: Series A </span> </div> <a href="https://academic.oup.com/biomedgerontology/advance-article/doi/10.1093/gerona/glad035/7008556?utm_source=advanceaccess&utm_campaign=biomedgerontology&utm_medium=email" target="_self" class="t-list-label"> An automated, home-cage, video monitoring-based mouse frailty index detects age-associated morbidity in C57BL and Diversity Outbred mice </a> <p class="publication_item__authors"> J Graham Ruby, PhD, Andrea Di Francesco, PhD, Paulo Ylagan, BS, Angela Luo, BA, Robert Keyser, BS, Owen Williams, BA, Sarah Spock, BS, Wenzhou Li, PhD, Nalien Vongtharangsy, BS, Sandip Chatterjee, PhD, Cricket A Sloan, MS, MS, Charles Ledogar, MEng, Veronica Kuiper, BS, Janessa Kite, MSc, Marcelo Cosino, Paulyn Cha, BS, Eleanor M Karlsson, DVM </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" 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class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 01.12.2023 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Cell Reports </span> </div> <a href="https://www.cell.com/cell-reports/fulltext/S2211-1247(22)01891-5?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2211124722018915%3Fshowall%3Dtrue" target="_self" class="t-list-label"> GOT1 regulates CD8+ effector and memory T cell generation </a> <p class="publication_item__authors"> Wei Xu, Chirag H Patel, Liang Zhao, Im-Hong Sun, Min-Hee Oh, Im-Meng Sun, Rachel S Helms, Jiayu Wen and Jonathan D Powell </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" 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Sorokin, Yi Liu, E. Louise Thomas, Jimmy D. 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1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 12.21.2022 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Scientific Reports </span> </div> <a href="https://www.nature.com/articles/s41598-022-25209-y" target="_self" class="t-list-label"> Global patterns of prognostic biomarkers across disease space </a> <p class="publication_item__authors"> Neha Murad and Eugene Melamud </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div 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1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 12.19.2022 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Cell Reports Methods </span> </div> <a href="https://www.sciencedirect.com/science/article/pii/S2667237522002533" target="_self" class="t-list-label"> Joint inference of physiological network and survival analysis identifies factors associated with aging rate </a> <p class="publication_item__authors"> Anurag Sethi and Eugene Melamud </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div 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2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://genomebiology.biomedcentral.com/articles/10.1186/s13059-022-02811-x "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" 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1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 11.23.2022 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Genome Biology </span> </div> <a href="https://genomebiology.biomedcentral.com/articles/10.1186/s13059-022-02811-x" target="_self" class="t-list-label"> The genetic and biochemical determinants of mRNA degradation rates in mammals </a> <p class="publication_item__authors"> Vikram Agarwal, David R. 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class="publication_item__meta t-label-small-medium"> <span class="date"> 11.23.2022 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Cell </span> </div> <a href="https://www.cell.com/cell/fulltext/S0092-8674(22)01318-6?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867422013186%3Fshowall%3Dtrue" target="_self" class="t-list-label"> Architecture of the outbred brown fat proteome defines regulators of metabolic physiology </a> <p class="publication_item__authors"> Haopeng Xiao, Luiz H M Bozi, Yizhi Sun, Christopher L Riley, Vivek M Philip, Mandy Chen, Jiaming Li, Tian Zhang, Evanna L Mills, Margo P Emont, Wenfei Sun, Anita Reddy, Ryan Garrity, Jiani Long, Tobias Becher, Laura Potano Vitas, Dina Laznik-Bogoslavski, Martha Ordonez, Xinyue Liu, Xiong Chen, Yun Wang, Weihai Liu, Nhien Tran, Yitong Liu, Yang Zhang, Aaron M Cypess, Andrew P White, Yuchen He, Rebecca Deng, Heiko Schöder, Joao A Paulo, Mark P Jedrychowski, Alexander S Banks, Yu-Hua Tseng, Paul Cohen, Linus T Tsai, Evan D Rosen, Samuel Klein, Maria Chondronikola, Fiona E McAllister, Nick Van Bruggen, Edward L Huttlin, Bruce M Spiegelman, Gary A Churchill, Steven P Gygi and Edward T Chouchani </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div 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0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 11.22.2022 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Journal of Proteome Research </span> </div> <a href="https://pubs.acs.org/doi/10.1021/acs.jproteome.2c00247" target="_self" class="t-list-label"> Conditional Fragment Ion Probabilities Improve Database Searching for Nonmonoisotopic Precursors </a> <p class="publication_item__authors"> Jonathon J. O’Brien, Meagan Gadzuk-Shea, Phillip M. Seitzer, Ramin Rad, Fiona E. McAllister, Devin K. Schweppe </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.nature.com/articles/s41587-022-01489-7 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" 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0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.nature.com/articles/s41587-022-01489-7 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.nature.com/articles/s41587-022-01489-7 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 10.10.2022 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Nature Biotechnology </span> </div> <a href="https://www.nature.com/articles/s41587-022-01489-7" target="_self" class="t-list-label"> Extending fluorescence anisotropy to large complexes using reversibly switchable proteins </a> <p class="publication_item__authors"> Andrea Volpato, Dirk Ollech, Jonatan Alvelid, Martina Damenti, Barbara Müller, Andrew G York, Maria Ingaramo, Ilaria Testa </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.frontiersin.org/articles/10.3389/fcvm.2022.1003246/full "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle 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1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.frontiersin.org/articles/10.3389/fcvm.2022.1003246/full "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" 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1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 10.06.2022 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Frontiers </span> </div> <a href="https://www.frontiersin.org/articles/10.3389/fcvm.2022.1003246/full" target="_self" class="t-list-label"> Calcification of the abdominal aorta is an under-appreciated cardiovascular disease risk factor in the general population </a> <p class="publication_item__authors"> Anurag Sethi, D. Leland Taylor, J. Graham Ruby†, Jagadish Venkataraman†, Elena Sorokin, Madeleine Cule and Eugene Melamud </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://opg.optica.org/boe/fulltext.cfm?uri=boe-13-11-5616&id=509237 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://opg.optica.org/boe/fulltext.cfm?uri=boe-13-11-5616&id=509237 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://opg.optica.org/boe/fulltext.cfm?uri=boe-13-11-5616&id=509237 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://opg.optica.org/boe/fulltext.cfm?uri=boe-13-11-5616&id=509237 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 10.04.2022 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Biomedical Optics Express </span> </div> <a href="https://opg.optica.org/boe/fulltext.cfm?uri=boe-13-11-5616&id=509237" target="_self" class="t-list-label"> Increasing the field-of-view in oblique plane microscopy via optical tiling </a> <p class="publication_item__authors"> Bingying Chen, Bo-Jui Chang, Felix Y. Zhou, Stephan Daetwyler, Etai Sapoznik, Benjamin A Nanes, Isabella Terrazas, Gabriel M. Gihana, Lizbeth Perez Castro, Isaac S. Chan, Maralice Conacci-Sorrell, Kevin M. Dean, Alfred Millett-Sikking, Andrew G. York and Reto Fiolka </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.sciencedirect.com/science/article/pii/S0005272822000512?via%3Dihub "> <svg height="30" viewBox="0 0 30 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3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.sciencedirect.com/science/article/pii/S0005272822000512?via%3Dihub "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.sciencedirect.com/science/article/pii/S0005272822000512?via%3Dihub "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 10.01.2022 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Biochimica et Biophysica Acta (BBA) – Bioenergetics </span> </div> <a href="https://www.sciencedirect.com/science/article/pii/S0005272822000512?via%3Dihub" target="_self" class="t-list-label"> Naked mole-rat and Damaraland mole-rat exhibit lower respiration in mitochondria, cellular and organismal levels </a> <p class="publication_item__authors"> Kang Nian Yap, Hoi Shan Wong, Chidambaram Ramanathan, Cristina Aurora Rodriguez-Wagner, Michael D Roberts, David A Freeman, Rochelle Buffenstein, and Yufeng Zhang </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.nature.com/articles/s41586-022-05358-w "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://www.nature.com/articles/s41586-022-05358-w "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.nature.com/articles/s41586-022-05358-w "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.nature.com/articles/s41586-022-05358-w "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 09.23.2022 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Nature </span> </div> <a href="https://www.nature.com/articles/s41586-022-05358-w" target="_self" class="t-list-label"> A RORγt+ cell instructs gut microbiota-specific Treg cell differentiation </a> <p class="publication_item__authors"> Ranit Kedmi, Tariq A. Najar, Kailin R. Mesa, Allyssa Grayson, Lina Kroehling, Yuhan Hao, Stephanie Hao, Maria Pokrovskii, Mo Xu, Jhimmy Talbot, Jiaxi Wang, Joe Germino, Caleb A. Lareau, Ansuman T. Satpathy, Mark S. Anderson, Terri M. Laufer, Iannis Aifantis, Juliet M. Bartleson, Paul M. Allen, Helena Paidassi, James M. Gardner, Marlon Stoeckius and Dan R. Littman </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.nature.com/articles/s41467-022-33175-2 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://www.nature.com/articles/s41467-022-33175-2 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.nature.com/articles/s41467-022-33175-2 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.nature.com/articles/s41467-022-33175-2 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 09.20.2022 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Nature Communications </span> </div> <a href="https://www.nature.com/articles/s41467-022-33175-2" target="_self" class="t-list-label"> Structure of the PAPP-ABP5 complex reveals mechanism of substrate recognition </a> <p class="publication_item__authors"> Russell A. Judge, Janani Sridar, Kathryn Tunyasunvunakool, Rinku Jain, John C. K. Wang, Christna Ouch, Jun Xu, Amirhossein Mafi, Aaron H. Nile, Clint Remarcik, Corey L. Smith, Crystal Ghosh, Chen Xu, Vincent Stoll, John Jumper, Amoolya H. Singh, Dan Eaton, Qi Hao </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.frontiersin.org/articles/10.3389/fragi.2022.932656/full "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://www.frontiersin.org/articles/10.3389/fragi.2022.932656/full "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.frontiersin.org/articles/10.3389/fragi.2022.932656/full "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.frontiersin.org/articles/10.3389/fragi.2022.932656/full "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 08.29.2022 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Frontiers in Aging </span> </div> <a href="https://www.frontiersin.org/articles/10.3389/fragi.2022.932656/full" target="_self" class="t-list-label"> The C. elegans Observatory: High-throughput exploration of behavioral aging </a> <p class="publication_item__authors"> Rex A. Kerr, Antoine E. Roux, Jérôme Goudeau, Cynthia Kenyon </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://genomebiology.biomedcentral.com/articles/10.1186/s13059-022-02723-w "> <svg height="30" 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2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://genomebiology.biomedcentral.com/articles/10.1186/s13059-022-02723-w "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 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1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 08.15.2022 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Genome Biology </span> </div> <a href="https://genomebiology.biomedcentral.com/articles/10.1186/s13059-022-02723-w" target="_self" class="t-list-label"> BindVAE: Dirichlet variational autoencoders for de novo motif discovery from accessible chromatin </a> <p class="publication_item__authors"> Meghana Kshirsagar, Han Yuan, Juan Lavista Ferres and Christina Leslie </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/pmic.202100242 "> <svg 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1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 08.14.2022 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Proteomics </span> </div> <a href="https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/pmic.202100242" target="_self" class="t-list-label"> Triple-threat quantitative multiplexed plasma proteomics analysis on immune complex disease MRL-lpr mice </a> <p class="publication_item__authors"> Aleksandr Gaun, Magdalena Preciado López, Niclas Olsson, John C.K. Wang, Leanne J.G. Chan, Jonathon O’Brien, Wenzhou Li, Jose Zavala-Solorio, Chunlian Zhang, Dan Eaton and Fiona E McAllister </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.nature.com/articles/s41592-022-01562-8 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://www.nature.com/articles/s41592-022-01562-8 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.nature.com/articles/s41592-022-01562-8 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.nature.com/articles/s41592-022-01562-8 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 08.08.2022 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Nature Methods </span> </div> <a href="https://www.nature.com/articles/s41592-022-01562-8" target="_self" class="t-list-label"> scBasset: sequence-based modeling of single-cell ATAC-seq using convolutional neural networks </a> <p class="publication_item__authors"> Han Yuan, David R. Kelley </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.mdpi.com/2218-1989/12/8/684 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" 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1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.mdpi.com/2218-1989/12/8/684 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.mdpi.com/2218-1989/12/8/684 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 07.25.2022 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Metabolites </span> </div> <a href="https://www.mdpi.com/2218-1989/12/8/684" target="_self" class="t-list-label"> MAVEN2: An Updated Open-Source Mass Spectrometry Exploration Platform </a> <p class="publication_item__authors"> Phillip Seitzer, Bryson Bennett, Eugene Melamud </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://elifesciences.org/articles/64329 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 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cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 07.15.2022 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> eLife </span> </div> <a href="https://elifesciences.org/articles/64329" target="_self" class="t-list-label"> Age and diet shape the genetic architecture of body weight in diversity outbred mice </a> <p class="publication_item__authors"> Kevin M. Wright, Andrew G. Deighan, Andrea Di Francesco, Adam Freund, Vladimir Jojic, Gary A. Churchill and Anil Raj </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.sciencedirect.com/science/article/pii/S0197458022001555?via%3Dihub "> <svg height="30" viewBox="0 0 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2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.sciencedirect.com/science/article/pii/S0197458022001555?via%3Dihub "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.sciencedirect.com/science/article/pii/S0197458022001555?via%3Dihub "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 07.11.2022 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Neurobiology of Aging </span> </div> <a href="https://www.sciencedirect.com/science/article/pii/S0197458022001555?via%3Dihub" target="_self" class="t-list-label"> Life-long dietary restrictions have negligible or damaging effects on late-life cognitive performance: A key role for genetics in outcomes </a> <p class="publication_item__authors"> Andrew R Ouellette, Niran Hadad, Andrew Deighan, Laura Robinson, Kristen O’Connell, Adam Freund, Gary A Churchill and Catherine C Kaczorowski </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.cell.com/cell-systems/fulltext/S2405-4712(22)00223-X "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://www.cell.com/cell-systems/fulltext/S2405-4712(22)00223-X "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.cell.com/cell-systems/fulltext/S2405-4712(22)00223-X "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.cell.com/cell-systems/fulltext/S2405-4712(22)00223-X "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 06.10.2022 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Cell Systems </span> </div> <a href="https://www.cell.com/cell-systems/fulltext/S2405-4712(22)00223-X" target="_self" class="t-list-label"> Diverse partial reprogramming strategies restore youthful gene expression and transiently suppress cell identity </a> <p class="publication_item__authors"> Antoine E. Roux, Chunlian Zhang, Jonathan Paw, José Zavala-Solorio, Evangelia Malahias, Twaritha Vijay, Ganesh Kolumam, Cynthia Kenyon, Jacob C. Kimmel </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.sciencedirect.com/science/article/pii/S0002929722001616?via%3Dihub "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://www.sciencedirect.com/science/article/pii/S0002929722001616?via%3Dihub "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.sciencedirect.com/science/article/pii/S0002929722001616?via%3Dihub "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.sciencedirect.com/science/article/pii/S0002929722001616?via%3Dihub "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 05.13.2022 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> American Journal of Human Genetics </span> </div> <a href="https://www.sciencedirect.com/science/article/pii/S0002929722001616?via%3Dihub" target="_self" class="t-list-label"> Analysis of MRI-derived spleen iron in the UK Biobank identifies genetic variation linked to iron homeostasis and hemolysis </a> <p class="publication_item__authors"> Elena P. Sorokin, Nicolas Basty, Brandon Whitcher, Yi Liu, Jimmy D. Bell, Robert L. Cohen, Madeleine Cule, E. Louise Thomas </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.sciencedirect.com/science/article/pii/S2666979X22000313?via%3Dihub "> <svg height="30" viewBox="0 0 30 30" 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3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.sciencedirect.com/science/article/pii/S2666979X22000313?via%3Dihub "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.sciencedirect.com/science/article/pii/S2666979X22000313?via%3Dihub "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 04.13.2022 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Cell Genomics </span> </div> <a href="https://www.sciencedirect.com/science/article/pii/S2666979X22000313?via%3Dihub" target="_self" class="t-list-label"> High-throughput characterization of the role of non-B DNA motifs on promoter function </a> <p class="publication_item__authors"> Ilias Georgakopoulos-Soares, Jesus Victorino, Guillermo E Parada, Vikram Agarwal, Jingjing Zhao, Hei Yuen Wong, Mubarak Ishaq Umar, Orry Elor, Allan Muhwezi, Joon-Yong An, Stephan J Sanders, Chun Kit Kwok, Fumitaka Inoue, Martin Hemberg and Nadav Ahituv </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://elifesciences.org/articles/72664 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://elifesciences.org/articles/72664 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://elifesciences.org/articles/72664 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://elifesciences.org/articles/72664 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 04.11.2022 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> eLife </span> </div> <a href="https://elifesciences.org/articles/72664" target="_self" class="t-list-label"> Automated, high-dimensional evaluation of physiological aging and resilience in outbred mice </a> <p class="publication_item__authors"> Zhenghao Chen, Anil Raj, GV Prateek, Andrea Di Francesco, Justin Liu, Brice E Keyes, Ganesh Kolumam, Vladimir Jojic, Adam Freund </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.pnas.org/doi/10.1073/pnas.2119593119 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://www.pnas.org/doi/10.1073/pnas.2119593119 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.pnas.org/doi/10.1073/pnas.2119593119 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.pnas.org/doi/10.1073/pnas.2119593119 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 04.08.2022 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> PNAS </span> </div> <a href="https://www.pnas.org/doi/10.1073/pnas.2119593119" target="_self" class="t-list-label"> rDNA array length is a major determinant of replicative lifespan in budding yeast </a> <p class="publication_item__authors"> Manuel Hotz, Nathaniel H. Thayer, David G. Hendrickson, Elizabeth L. Schinski, Jun Xu, Daniel E. Gottschling </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.nature.com/articles/s41598-022-09438-9 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://www.nature.com/articles/s41598-022-09438-9 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.nature.com/articles/s41598-022-09438-9 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.nature.com/articles/s41598-022-09438-9 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 04.01.2022 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Scientific Reports </span> </div> <a href="https://www.nature.com/articles/s41598-022-09438-9" target="_self" class="t-list-label"> Bladder cancer cells shift rapidly and spontaneously to cisplatin-resistant oxidative phosphorylation that is trackable in real time </a> <p class="publication_item__authors"> Tong Xu, Jason A. Junge, Alireza Delfarah, Yi-Tsung Lu, Cosimo Arnesano, Maheen Iqbal, Kevin Delijani, Tien-Chan Hsieh, Emmanuelle Hodara, Hemal H. Mehta, Pinchas Cohen, Nicholas A. Graham, Scott E. Fraser and Amir Goldkorn </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.nature.com/articles/s41592-022-01417-2 "> <svg height="30" viewBox="0 0 30 30" width="30"><g 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</a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.nature.com/articles/s41592-022-01417-2 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 03.21.2022 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Nature Methods </span> </div> <a href="https://www.nature.com/articles/s41592-022-01417-2" target="_self" class="t-list-label"> DaXi-high-resolution, large imaging volume and multi-view single-objective light-sheet microscopy </a> <p class="publication_item__authors"> Bin Yang, Merlin Lange, Alfred Millett-Sikking, Xiang Zhao, Jordão Bragantini, Shruthi VijayKumar, Mason Kamb, Rafael Gómez-Sjöberg, Ahmet Can Solak, Wanpeng Wang, Hirofumi Kobayashi, Matthew N. McCarroll, Lachlan W. Whitehead, Reto P. Fiolka, Thomas B. Kornberg, Andrew G. York, Loic A. Royer </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://onlinelibrary.wiley.com/doi/10.1111/acel.13589 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://onlinelibrary.wiley.com/doi/10.1111/acel.13589 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://onlinelibrary.wiley.com/doi/10.1111/acel.13589 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://onlinelibrary.wiley.com/doi/10.1111/acel.13589 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 03.08.2022 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Aging Cell </span> </div> <a href="https://onlinelibrary.wiley.com/doi/10.1111/acel.13589" target="_self" class="t-list-label"> CD38 inhibitor 78c increases mice lifespan and healthspan in a model of chronological aging </a> <p class="publication_item__authors"> Thais R. Peclat, Katie L. Thompson, Gina M. Warner, Claudia C.S. Chini, Mariana G. Tarragó, Delaram Z. Mazdeh, Chunlian Zhang, Jose Zavala-Solorio, Ganesh Kolumam, Yao Liang Wong, Robert L. Cohen, Eduardo N. Chini </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.nature.com/articles/s41598-022-07556-y "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://www.nature.com/articles/s41598-022-07556-y "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.nature.com/articles/s41598-022-07556-y "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.nature.com/articles/s41598-022-07556-y "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 03.08.2022 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Scientific Reports </span> </div> <a href="https://www.nature.com/articles/s41598-022-07556-y" target="_self" class="t-list-label"> Precision MRI phenotyping enables detection of small changes in body composition for longitudinal cohorts </a> <p class="publication_item__authors"> Brandon Whitcher, Marjola Thanaj, Madeleine Cule, Yi Liu, Nicolas Basty, Elena P. Sorokin, Jimmy D. Bell, E. Louise Thomas </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.nature.com/articles/s43018-022-00334-9 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" 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0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.nature.com/articles/s43018-022-00334-9 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.nature.com/articles/s43018-022-00334-9 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 03.07.2022 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Nature Cancer </span> </div> <a href="https://www.nature.com/articles/s43018-022-00334-9" target="_self" class="t-list-label"> An anti-PD-1-GITR-L bispecific agonist induces GITR clustering-mediated T cell activation for cancer immunotherapy </a> <p class="publication_item__authors"> Sarah Chan, Nicole Belmar, Sun Ho, Bryan Rogers, Marcia Stickler, Michelle Graham, Eileen Lee, Ninian Tran, Dong Zhang, Priyanka Gupta, Mien Sho, Tracy MacDonough, Andrew Woolley, Han Kim, Hong Zhang, Wei Liu, Pingping Zheng, Zoltan Dezso, Kyle Halliwill, Michele Ceccarelli, Susan Rhodes, Archana Thakur, Charles M. Forsyth, Mengli Xiong, Siu Sze Tan, Ramesh Iyer, Marc Lake, Enrico Digiammarino, Li Zhou, Lance Bigelow, Kenton Longenecker, Russell A. Judge, Cassie Liu, Max Trumble, Jonathan P. Remis, Melvin Fox, Belinda Cairns, Yoshiko Akamatsu, Diane Hollenbaugh, Fiona Harding and Hamsell M. Alvarez </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://doi.org/10.7554/eLife.70283 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" 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1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://doi.org/10.7554/eLife.70283 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://doi.org/10.7554/eLife.70283 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 02.04.2022 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> eLife </span> </div> <a href="https://doi.org/10.7554/eLife.70283" target="_self" class="t-list-label"> Novel insights from a multiomics dissection of the Hayflick limit </a> <p class="publication_item__authors"> Michelle Chan, Han Yuan, Ilya Soifer, Tobias M Maile, Rebecca Y Wang, Andrea Ireland, Jonathon J O’Brien, Jérôme Goudeau, Leanne JG Chan, Twaritha Vijay, Adam Freund, Cynthia Kenyon, Bryson D Bennett, Fiona E McAllister, David R Kelley, Margaret Roy, Robert L Cohen, Arthur D Levinson, David Botstein, David G Hendrickson </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" 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.243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://link.springer.com/article/10.1007%2Fs11357-022-00522-6 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://link.springer.com/article/10.1007%2Fs11357-022-00522-6 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 02.02.2022 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> GeroScience </span> </div> <a href="https://link.springer.com/article/10.1007%2Fs11357-022-00522-6" target="_self" class="t-list-label"> Naked mole-rats maintain cardiac function and body composition well into their fourth decade of life </a> <p class="publication_item__authors"> Emine Can, Megan Smith, Bastiaan J. Boukens, Ruben Coronel, Rochelle Buffenstein, Johannes Riegler </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.nature.com/articles/s41590-021-01121-x "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://www.nature.com/articles/s41590-021-01121-x "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.nature.com/articles/s41590-021-01121-x "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.nature.com/articles/s41590-021-01121-x "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 01.20.2022 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Nature Immunology </span> </div> <a href="https://www.nature.com/articles/s41590-021-01121-x" target="_self" class="t-list-label"> The immunoregulatory landscape of human tuberculosis granulomas </a> <p class="publication_item__authors"> Erin F. McCaffrey, Michele Donato, Leeat Keren, Zhenghao Chen, Alea Delmastro, Megan B. Fitzpatrick, Sanjana Gupta, Noah F. Greenwald, Alex Baranski, William Graf, Rashmi Kumar, Marc Bosse, Christine Camacho Fullaway, Pratista K. Ramdial, Erna Forgó, Vladimir Jojic, David Van Valen, Smriti Mehra, Shabaana A. Khader, Sean C. Bendall, Matt van de Rijn, Daniel Kalman, Deepak Kaushal, Robert L. Hunter, Niaz Banaei, Adrie J. C. Steyn, Purvesh Khatri, Michael Angelo </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.sciencedirect.com/science/article/pii/S2405471221004877?via%3Dihub "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://www.sciencedirect.com/science/article/pii/S2405471221004877?via%3Dihub "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.sciencedirect.com/science/article/pii/S2405471221004877?via%3Dihub "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.sciencedirect.com/science/article/pii/S2405471221004877?via%3Dihub "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 01.19.2022 </span> <span class="post-type" data-slug="commentaries-reviews"> Commentaries & Reviews </span> <span class="journal"> Cell Systems </span> </div> <a href="https://www.sciencedirect.com/science/article/pii/S2405471221004877?via%3Dihub" target="_self" class="t-list-label"> Evaluation of Williams et al.: On multiomics and mediation </a> <p class="publication_item__authors"> Sean R. Hackett </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://diabetesjournals.org/care/article-abstract/45/2/460/139118/Estimating-the-Effect-of-Liver-and-Pancreas-Volume?redirectedFrom=fulltext "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://diabetesjournals.org/care/article-abstract/45/2/460/139118/Estimating-the-Effect-of-Liver-and-Pancreas-Volume?redirectedFrom=fulltext "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://diabetesjournals.org/care/article-abstract/45/2/460/139118/Estimating-the-Effect-of-Liver-and-Pancreas-Volume?redirectedFrom=fulltext "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://diabetesjournals.org/care/article-abstract/45/2/460/139118/Estimating-the-Effect-of-Liver-and-Pancreas-Volume?redirectedFrom=fulltext "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 01.17.2022 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Diabetes Care </span> </div> <a href="https://diabetesjournals.org/care/article-abstract/45/2/460/139118/Estimating-the-Effect-of-Liver-and-Pancreas-Volume?redirectedFrom=fulltext" target="_self" class="t-list-label"> Estimating the Effect of Liver and Pancreas Volume and Fat Content on Risk of Diabetes: A Mendelian Randomization Study </a> <p class="publication_item__authors"> Susan Martin; Elena P. Sorokin; E. Louise Thomas; Naveed Sattar; Madeleine Cule; Jimmy D. Bell; Hanieh Yaghootkar </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.nature.com/articles/s41586-021-04183-x "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://www.nature.com/articles/s41586-021-04183-x "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.nature.com/articles/s41586-021-04183-x "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.nature.com/articles/s41586-021-04183-x "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 12.08.2021 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Nature </span> </div> <a href="https://www.nature.com/articles/s41586-021-04183-x" target="_self" class="t-list-label"> Exercise plasma boosts memory and dampens brain inflammation via clusterin </a> <p class="publication_item__authors"> Zurine De Miguel, Nathalie Khoury, Michael J. Betley, Benoit Lehallier, Drew Willoughby, Niclas Olsson, Andrew C. Yang, Oliver Hahn, Nannan Lu, Ryan T. Vest, Liana N. Bonanno, Lakshmi Yerra, Lichao Zhang, Nay Lui Saw, J. Kaci Fairchild, Davis Lee, Hui Zhang, Patrick L. McAlpine, Kévin Contrepois, Mehrdad Shamloo, Joshua E. Elias, Thomas A. Rando and Tony Wyss-Coray </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://academic.oup.com/biomedgerontology/article/77/5/956/6413718?login=false "> <svg height="30" 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1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://academic.oup.com/biomedgerontology/article/77/5/956/6413718?login=false "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 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2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 10.28.2021 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> J Gerontol A Biol Sci Med Sci </span> </div> <a href="https://academic.oup.com/biomedgerontology/article/77/5/956/6413718?login=false" target="_self" class="t-list-label"> Impact of Large Granular Lymphocyte Leukemia on Blood DNA Methylation and Epigenetic Clock Modeling in Fischer 344 Rats </a> <p class="publication_item__authors"> Giovanni E Finesso, Ross A McDevitt, Roshni Roy, Lauren R Brinster, Andrea Di Francesco, Theresa Meade, Rafael de Cabo, Luigi Ferrucci and Kathy A Perdue </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" 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0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 10.27.2021 </span> <span class="post-type" data-slug="commentaries-reviews"> Commentaries & Reviews </span> <span class="journal"> Aging </span> </div> <a href="https://www.aging-us.com/article/203661" target="_self" class="t-list-label"> GWAS of canines identifies potential aging determinants </a> <p class="publication_item__authors"> Timothy M Robinette and Sergiy Libert </p> </div> </article> 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target="_blank" href="mailto:?body=https://onlinelibrary.wiley.com/doi/10.1111/acel.13481 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 10.21.2021 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Aging Cell </span> </div> <a href="https://onlinelibrary.wiley.com/doi/10.1111/acel.13481" target="_self" class="t-list-label"> Drosophila p38 MAPK interacts with BAG-3/starvin to regulate age-dependent protein homeostasis </a> <p class="publication_item__authors"> Sarah M. Ryan, Michael Almassey, Amelia M. Burch, Gia Ngo, Julia M. Martin, David Myers, Devin Compton, Shira Archie, Megan Cross, Lauren Naeger, Ashley Salzman, Alyssa Virola-Iarussi, Scott A. Barbee, Nathan T. Mortimer, Subhabrata Sanyal and Alysia D. Vrailas-Mortimer </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.nature.com/articles/s41592-021-01252-x "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://www.nature.com/articles/s41592-021-01252-x "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.nature.com/articles/s41592-021-01252-x "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.nature.com/articles/s41592-021-01252-x "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 10.04.2021 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Nature Methods </span> </div> <a href="https://www.nature.com/articles/s41592-021-01252-x" target="_self" class="t-list-label"> Effective gene expression prediction from sequence by integrating long-range interactions </a> <p class="publication_item__authors"> Žiga Avsec, Vikram Agarwal, Daniel Visentin, Joseph R. Ledsam, Agnieszka Grabska-Barwinska, Kyle R. Taylor, Yannis Assael, John Jumper, Pushmeet Kohli, David R. Kelley </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://academic.oup.com/genetics/article/220/1/iyab157/6375446?login=true "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://academic.oup.com/genetics/article/220/1/iyab157/6375446?login=true "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://academic.oup.com/genetics/article/220/1/iyab157/6375446?login=true "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://academic.oup.com/genetics/article/220/1/iyab157/6375446?login=true "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 09.25.2021 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Genetics </span> </div> <a href="https://academic.oup.com/genetics/article/220/1/iyab157/6375446?login=true" target="_self" class="t-list-label"> Intermittent fasting and caloric restriction interact with genetics to shape physiological health in mice </a> <p class="publication_item__authors"> Guozhu Zhang, Andrew Deighan, Anil Raj, Laura Robinson, Hannah J. Donato, Gaven Garland, Mackenzie Leland, Baby Martin-McNulty, Ganesh A. Kolumam, Johannes Riegler, Adam Freund, Kevin M. Wright, Gary A. Churchill </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.cell.com/immunity/pdfExtended/S1074-7613(21)00263-6 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://www.cell.com/immunity/pdfExtended/S1074-7613(21)00263-6 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.cell.com/immunity/pdfExtended/S1074-7613(21)00263-6 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.cell.com/immunity/pdfExtended/S1074-7613(21)00263-6 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 09.17.2021 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Cell Press </span> </div> <a href="https://www.cell.com/immunity/pdfExtended/S1074-7613(21)00263-6" target="_self" class="t-list-label"> Protein kinase R and the integrated stress response drive immunopathology caused by mutations in the RNA deaminase ADAR1 </a> <p class="publication_item__authors"> Megan Maurano, Jessica M. Snyder, Caitlin Connelly, Jorge Henao-Mejia, Carmela Sidrauski, Daniel B. Stetson </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://onlinelibrary.wiley.com/doi/10.1111/brv.12791 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://onlinelibrary.wiley.com/doi/10.1111/brv.12791 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://onlinelibrary.wiley.com/doi/10.1111/brv.12791 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://onlinelibrary.wiley.com/doi/10.1111/brv.12791 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 09.03.2021 </span> <span class="post-type" data-slug="commentaries-reviews"> Commentaries & Reviews </span> <span class="journal"> Biological Reviews Cambridge Philosophical Society </span> </div> <a href="https://onlinelibrary.wiley.com/doi/10.1111/brv.12791" target="_self" class="t-list-label"> The naked truth: a comprehensive clarification and classification of current ‘myths’ in naked mole-rat biology </a> <p class="publication_item__authors"> Rochelle Buffenstein, Vincent Amoroso, Blazej Andziak, Stanislav Avdieiev, Jorge Azpurua, Alison J. Barker, Nigel C. Bennett, Miguel A. Brieño-Enríquez, Gary N. Bronner, Clive Coen, Martha A. Delaney, Christine M. Dengler-Crish, Yael H. Edrey, Chris G. Faulkes, Daniel Frankel, Gerard Friedlander, Patrick A. Gibney, Vera Gorbunova, Christopher Hine, Melissa M. Holmes, Jennifer U. M. Jarvis, Yoshimi Kawamura, Nobuyuki Kutsukake, Cynthia Kenyon, Walid T. Khaled, Takefumi Kikusui, Joseph Kissil, Samantha Lagestee, John Larson, Amanda Lauer, Leonid A. Lavrenchenko, Angela Lee, Jonathan B. Levitt, Gary R. Lewin, Kaitlyn N. Lewis Hardell, TzuHua D. Lin, Matthew J. Mason, Dan McCloskey, Mary McMahon, Kyoko Miura, Kazutaka Mogi, Vikram Narayan, Timothy P. O’Connor, Kazuo Okanoya, M. Justin O’Riain, Thomas J. Park, Ned J. Place, Katie Podshivalova, Matthew E. Pamenter, Sonja J. Pyott, Jane Reznick, J. Graham Ruby, Adam B. Salmon, Joseph Santos-Sacchi, Diana K. Sarko, Andrei Seluanov, Alyssa Shepard, Megan Smith, Kenneth B. Storey, Xiao Tian, Emily N. Vice, Mélanie Viltard, Akiyuki Watarai, Ewa Wywial, Masanori Yamakawa, Elena D. 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1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 08.24.2021 </span> <span class="post-type" data-slug="commentaries-reviews"> Commentaries & Reviews </span> <span class="journal"> Advances in Experimental Medicine and Biology </span> </div> <a href="https://link.springer.com/chapter/10.1007/978-3-030-65943-1_17" target="_self" class="t-list-label"> Some Exciting Future Directions for Work on Naked Mole-Rats </a> <p class="publication_item__authors"> Ewan St. J. Smith, Thomas J. Park, Melissa M. Holmes and Rochelle Buffenstein </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.nature.com/articles/s43587-021-00102-x "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://www.nature.com/articles/s43587-021-00102-x "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.nature.com/articles/s43587-021-00102-x "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.nature.com/articles/s43587-021-00102-x "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 07.26.2021 </span> <span class="post-type" data-slug="commentaries-reviews"> Commentaries & Reviews </span> <span class="journal"> Nature Aging </span> </div> <a href="https://www.nature.com/articles/s43587-021-00102-x" target="_self" class="t-list-label"> An inflammatory aging clock (iAge) based on deep learning tracks multimorbidity, immunosenescence, frailty and cardiovascular aging </a> <p class="publication_item__authors"> Nazish Sayed, Yingxiang Huang, Khiem Nguyen, Zuzana Krejciova-Rajaniemi, Anissa P. Grawe, Tianxiang Gao, Robert Tibshirani, Trevor Hastie, Ayelet Alpert, Lu Cui, Tatiana Kuznetsova, Yael Rosenberg-Hasson, Rita Ostan, Daniela Monti, Benoit Lehallier, Shai S. Shen-Orr, Holden T. Maecker, Cornelia L. Dekker, Tony Wyss-Coray, Claudio Franceschi, Vladimir Jojic, François Haddad, José G. Montoya, Joseph C. Wu, Mark M. Davis and David Furman </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.nature.com/articles/s41592-021-01175-7 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://www.nature.com/articles/s41592-021-01175-7 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.nature.com/articles/s41592-021-01175-7 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.nature.com/articles/s41592-021-01175-7 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 06.28.2021 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Nature Methods </span> </div> <a href="https://www.nature.com/articles/s41592-021-01175-7" target="_self" class="t-list-label"> Real-time multi-angle projection imaging of biological dynamics </a> <p class="publication_item__authors"> Bo-Jui Chang, James D. Manton, Etai Sapoznik, Theresa Pohlkamp, Tamara S. Terrones, Erik S. Welf, Vasanth S. Murali, Philippe Roudot, Kayley Hake, Lachlan Whitehead, Andrew G. York, Kevin M. Dean and Reto Fiolka </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://elifesciences.org/articles/65554 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" 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1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://elifesciences.org/articles/65554 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" 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1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 06.15.2021 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> eLife </span> </div> <a href="https://elifesciences.org/articles/65554" target="_self" class="t-list-label"> Genetic architecture of 11 organ traits derived from abdominal MRI using deep learning </a> <p class="publication_item__authors"> Yi Liu, Nicolas Basty, Brandon Whitcher, Jimmy D Bell, Elena P Sorokin, Nick van Bruggen, E Louise Thomas, Madeleine Cule </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div 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href="mailto:?body=https://www.nature.com/articles/s41467-021-23836-z "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 06.08.2021 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Nature Communications </span> </div> <a href="https://www.nature.com/articles/s41467-021-23836-z" target="_self" class="t-list-label"> Sugar phosphate activation of the stress sensor eIF2B </a> <p class="publication_item__authors"> Qi Hao, Jin-Mi Heo, Boguslaw P. Nocek, Kevin G. Hicks, Vincent S. Stoll, Clint Remarcik, Sean Hackett, Lauren LeBon, Rinku Jain, Dan Eaton, Jared Rutter, Yao Liang Wong, Carmela Sidrauski </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.nature.com/articles/s41467-021-23134-8 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://www.nature.com/articles/s41467-021-23134-8 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.nature.com/articles/s41467-021-23134-8 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.nature.com/articles/s41467-021-23134-8 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 06.07.2021 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Nature Communications </span> </div> <a href="https://www.nature.com/articles/s41467-021-23134-8" target="_self" class="t-list-label"> Leveraging supervised learning for functionally informed fine-mapping of cis-eQTLs identifies an additional 20,913 putative causal eQTLs </a> <p class="publication_item__authors"> Qingbo S. Wang, David R. Kelley, Jacob Ulirsch, Masahiro Kanai, Shuvom Sadhuka, Ran Cui, Carlos Albors, Nathan Cheng, Yukinori Okada, The Biobank Japan Project, Francois Aguet, Kristin G. Ardlie, Daniel G. MacArthur and Hilary K. Finucane </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://diabetesjournals.org/diabetes/article/70/8/1843/137911/Genetic-Evidence-for-Different-Adiposity "> <svg height="30" 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1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://diabetesjournals.org/diabetes/article/70/8/1843/137911/Genetic-Evidence-for-Different-Adiposity "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 05.12.2021 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Diabetes </span> </div> <a href="https://diabetesjournals.org/diabetes/article/70/8/1843/137911/Genetic-Evidence-for-Different-Adiposity" target="_self" class="t-list-label"> Genetic Evidence for Different Adiposity Phenotypes and Their Opposing Influences on Ectopic Fat and Risk of Cardiometabolic Disease </a> <p class="publication_item__authors"> Susan Martin, Madeleine Cule, Nicolas Basty, Jessica Tyrrell, Robin N Beaumont, Andrew R Wood, Timothy M Frayling, Elena Sorokin, Brandon Whitcher, Yi Liu, Jimmy D Bell, E Louise Thomas and Hanieh Yaghootkar </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 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11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.cell.com/cell-reports/fulltext/S2211-1247(21)00362-4 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 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.591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 04.27.2021 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Cell Reports </span> </div> <a href="https://www.cell.com/cell-reports/fulltext/S2211-1247(21)00362-4" target="_self" class="t-list-label"> Differentiation reveals latent features of aging and an energy barrier in murine myogenesis </a> <p class="publication_item__authors"> Kimmel J, Yi N, Roy M, Hendrickson D, Kelley D. </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://genome.cshlp.org/content/31/5/866.long "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://genome.cshlp.org/content/31/5/866.long "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://genome.cshlp.org/content/31/5/866.long "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://genome.cshlp.org/content/31/5/866.long "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 04.20.2021 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Genome Research </span> </div> <a href="https://genome.cshlp.org/content/31/5/866.long" target="_self" class="t-list-label"> Genome-wide strand asymmetry in massively parallel reporter activity favors genic strands </a> <p class="publication_item__authors"> Brian S. Roberts, E. Christopher Partridge, Bryan A. Moyers, Vikram Agarwal, Kimberly M. Newberry, Beth K. Martin, Jay Shendure, Richard M. Myers and Gregory M. Cooper </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://faseb.onlinelibrary.wiley.com/doi/ftr/10.1096/fj.202100116R "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://faseb.onlinelibrary.wiley.com/doi/ftr/10.1096/fj.202100116R "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://faseb.onlinelibrary.wiley.com/doi/ftr/10.1096/fj.202100116R "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://faseb.onlinelibrary.wiley.com/doi/ftr/10.1096/fj.202100116R "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 04.19.2021 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> FASEB Journal </span> </div> <a href="https://faseb.onlinelibrary.wiley.com/doi/ftr/10.1096/fj.202100116R" target="_self" class="t-list-label"> It’s about time; divergent circadian clocks in livers of mice and naked mole-rats </a> <p class="publication_item__authors"> Soumyaditya Ghosh, Kaitlyn N. Lewis, Richa Tulsian, Artem A. Astafev, Rochelle Buffenstein and Roman V. Kondratov </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://elifesciences.org/articles/62653 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" 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1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://elifesciences.org/articles/62653 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" 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1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 04.13.2021 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> eLife </span> </div> <a href="https://elifesciences.org/articles/62653" target="_self" class="t-list-label"> A genetic screen identifies new steps in oocyte maturation that enhance proteostasis in the immortal germ lineage </a> <p class="publication_item__authors"> Samaddar M, Goudeau J, Sanchez M, Hall D, Bohnert A, Ingaramo M, Kenyon C </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div 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3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.science.org/doi/full/10.1126/science.abf6648?rfr_dat=cr_pub++0pubmed&url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 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.677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 04.12.2021 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Science </span> </div> <a href="https://www.science.org/doi/full/10.1126/science.abf6648?rfr_dat=cr_pub++0pubmed&url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org" target="_self" class="t-list-label"> Shared B cell memory to coronaviruses and other pathogens varies in human age groups and tissues </a> <p class="publication_item__authors"> Fan Yang, Sandra C A Nielsen, Ramona A Hoh, Katharina Röltgen, Oliver Fabian Wirz, Emily Haraguchi, Grace H Jean, Ji-Yeun Lee, Tho D Pham, Katherine J L Jackson, Krishna M Roskin, Yi Liu, Khoa Nguyen, Robert S Ohgami, Eleanor M Osborne, Kari C Nadeau, Claus U Niemann, Julie Parsonnet and Scott D Boyd </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 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Kimmel and David R. Kelley </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://genome.cshlp.org/content/early/2021/02/24/gr.268581.120.abstract?sid=255f0f11-800a-46a7-9e41-7a00b3043f9e "> <svg 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2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://genome.cshlp.org/content/early/2021/02/24/gr.268581.120.abstract?sid=255f0f11-800a-46a7-9e41-7a00b3043f9e "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://genome.cshlp.org/content/early/2021/02/24/gr.268581.120.abstract?sid=255f0f11-800a-46a7-9e41-7a00b3043f9e "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 02.24.2021 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Genome Research </span> </div> <a href="https://genome.cshlp.org/content/early/2021/02/24/gr.268581.120.abstract?sid=255f0f11-800a-46a7-9e41-7a00b3043f9e" target="_self" class="t-list-label"> Semi-supervised adversarial neural networks for single-cell classification </a> <p class="publication_item__authors"> Kimmel J, Kelley D </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://onlinelibrary.wiley.com/doi/10.1111/acel.13313 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://onlinelibrary.wiley.com/doi/10.1111/acel.13313 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://onlinelibrary.wiley.com/doi/10.1111/acel.13313 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://onlinelibrary.wiley.com/doi/10.1111/acel.13313 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 02.09.2021 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Aging Cell </span> </div> <a href="https://onlinelibrary.wiley.com/doi/10.1111/acel.13313" target="_self" class="t-list-label"> Inhibition of longevity regulator PAPP-A modulates tissue homeostasis via restraint of mesenchymal stromal cells </a> <p class="publication_item__authors"> Mary Mohrin, Justin Liu, Jose Zavala-Solorio, Sakshi Bhargava, John Maxwell Trumble, Alyssa Brito, Dorothy Hu, Daniel Brooks, Georgios Koukos, Lama Alabdulaaly, Jonathan S. Paw, Kayley Hake, Ganesh Kolumam, Mary L. Bouxsein, Roland Baron, Yuliya Kutskova, and Adam Freund </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://onlinelibrary.wiley.com/doi/10.1111/acel.13313 "> <svg height="30" 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3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://onlinelibrary.wiley.com/doi/10.1111/acel.13313 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://onlinelibrary.wiley.com/doi/10.1111/acel.13313 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 02.09.2021 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Aging Cell </span> </div> <a href="https://onlinelibrary.wiley.com/doi/10.1111/acel.13313" target="_self" class="t-list-label"> Inhibition of longevity regulator PAPP‐A modulates tissue homeostasis via restraint of mesenchymal stromal cells </a> <p class="publication_item__authors"> Mohrin M, Liu J, Zavala-Solorio J, Bhargava S, Trumble J, Brito A, Hu D, Brooks D, Koukos G, Alabdulaaly L, Paw J, Hake K, Koluman G, Bouxsein M, Baron R, Kutskova Y, Freund A </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" 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2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 01.29.2021 </span> <span class="post-type" data-slug="commentaries-reviews"> Commentaries & Reviews </span> <span class="journal"> Science </span> </div> <a href="https://www.science.org/doi/10.1126/science.abf7962?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed" target="_self" class="t-list-label"> Colony-specific dialects of naked mole-rats </a> <p class="publication_item__authors"> Rochelle Buffenstein </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://pubs.acs.org/doi/10.1021/acs.jproteome.0c00681 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://pubs.acs.org/doi/10.1021/acs.jproteome.0c00681 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://pubs.acs.org/doi/10.1021/acs.jproteome.0c00681 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://pubs.acs.org/doi/10.1021/acs.jproteome.0c00681 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 01.26.2021 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Journal of Proteome Research </span> </div> <a href="https://pubs.acs.org/doi/10.1021/acs.jproteome.0c00681" target="_self" class="t-list-label"> Automated 16-Plex Plasma Proteomics with Real-Time Search and Ion Mobility Mass Spectrometry Enables Large-Scale Profiling in Naked Mole-Rats and Mice </a> <p class="publication_item__authors"> Aleksandr Gaun, Kaitlyn N. Lewis Hardell, Niclas Olsson, Jonathon J. O’Brien, Sudha Gollapudi, Megan Smith, Graeme McAlister, Romain Huguet, Robert Keyser, Rochelle Buffenstein and Fiona E. McAllister </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.nature.com/articles/s43587-020-00012-4 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://www.nature.com/articles/s43587-020-00012-4 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.nature.com/articles/s43587-020-00012-4 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.nature.com/articles/s43587-020-00012-4 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 01.14.2021 </span> <span class="post-type" data-slug="commentaries-reviews"> Commentaries & Reviews </span> <span class="journal"> Nature Aging </span> </div> <a href="https://www.nature.com/articles/s43587-020-00012-4" target="_self" class="t-list-label"> Opportunities for new insight into aging from the naked mole-rat and other non-traditional models </a> <p class="publication_item__authors"> Rochelle Buffenstein and J. Graham Ruby </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" 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Kass and Kavita Sharma </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.aging-us.com/article/202454/text "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" 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1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 12.30.2020 </span> <span class="post-type" data-slug="commentaries-reviews"> Commentaries & Reviews </span> <span class="journal"> Aging </span> </div> <a href="https://www.aging-us.com/article/202454/text" target="_self" class="t-list-label"> ARDD 2020: from aging mechanisms to interventions </a> <p class="publication_item__authors"> Garik V Mkrtchyan, Kotb Abdelmohsen, Pénélope Andreux, Ieva Bagdonaite, Nir Barzilai, Søren Brunak, Filipe Cabreiro, Rafael de Cabo, Judith Campisi, Ana Maria Cuervo, Marco Demaria, Collin Y Ewald, Evandro Fei Fang, Richard Faragher, Luigi Ferrucci, Adam Freund, Carlos G Silva-García, Anastasia Georgievskaya, Vadim N Gladyshev, David J Glass, Vera Gorbunova, Aubrey de Grey, Wei-Wu He, Jan Hoeijmakers, Eva Hoffmann, Steve Horvath, Riekelt H Houtkooper, Majken K Jensen, Martin Borch Jensen, Alice Kane, Moustapha Kassem, Peter de Keizer, Brian Kennedy, Gerard Karsenty, Dudley W Lamming, Kai-Fu Lee, Nanna MacAulay, Polina Mamoshina, Jim Mellon, Marte Molenaars, Alexey Moskalev, Andreas Mund, Laura Niedernhofer, Brenna Osborne, Heidi H Pak, Andrey Parkhitko, Nuno Raimundo, Thomas A Rando, Lene Juel Rasmussen, Carolina Reis, Christian G Riedel, Anais Franco-Romero, Björn Schumacher, David A Sinclair, Yousin Suh, Pam R Taub, Debra Toiber, Jonas T Treebak, Dario Riccardo Valenzano, Eric Verdin, Jan Vijg, Sergey Young, Lei Zhang, Daniela Bakula, Alex Zhavoronkov and Morten Scheibye-Knudsen </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> 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23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://aocs.onlinelibrary.wiley.com/doi/10.1002/lipd.12286 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 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1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 12.17.2020 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Lipids </span> </div> <a href="https://aocs.onlinelibrary.wiley.com/doi/10.1002/lipd.12286" target="_self" class="t-list-label"> Naked Mole-Rat, a Rodent with an Apolipoprotein A-I Dimer </a> <p class="publication_item__authors"> Don L. Puppione, Denise P. Tran, Muhammad A. Zenaidee, Sarada Charugundla, Julian P. Whitelegge and Rochelle Buffenstein </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://febs.onlinelibrary.wiley.com/doi/10.1002/2211-5463.13021 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://febs.onlinelibrary.wiley.com/doi/10.1002/2211-5463.13021 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://febs.onlinelibrary.wiley.com/doi/10.1002/2211-5463.13021 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://febs.onlinelibrary.wiley.com/doi/10.1002/2211-5463.13021 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 12.14.2020 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> FEBS Open Biology </span> </div> <a href="https://febs.onlinelibrary.wiley.com/doi/10.1002/2211-5463.13021" target="_self" class="t-list-label"> Cardiac pericytes function as key vasoactive cells to regulate homeostasis and disease </a> <p class="publication_item__authors"> Linda L. Lee, Aarif Y. Khakoo and Vishnu Chintalgattu </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.mdpi.com/2076-2607/8/12/1900 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://www.mdpi.com/2076-2607/8/12/1900 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.mdpi.com/2076-2607/8/12/1900 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.mdpi.com/2076-2607/8/12/1900 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 11.30.2020 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Microorganisms </span> </div> <a href="https://www.mdpi.com/2076-2607/8/12/1900" target="_self" class="t-list-label"> The Exploration of Novel Regulatory Relationships Drives Haloarchaeal Operon-Like Structural Dynamics over Short Evolutionary Distances </a> <p class="publication_item__authors"> Phillip Seitzer, Andrew I Yao, Ariana Cisneros and Marc T Facciotti </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://onlinelibrary.wiley.com/doi/10.1111/acel.13269 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://onlinelibrary.wiley.com/doi/10.1111/acel.13269 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://onlinelibrary.wiley.com/doi/10.1111/acel.13269 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://onlinelibrary.wiley.com/doi/10.1111/acel.13269 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 11.19.2020 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Aging Cell </span> </div> <a href="https://onlinelibrary.wiley.com/doi/10.1111/acel.13269" target="_self" class="t-list-label"> Rapamycin-mediated mouse lifespan extension: Late-life dosage regimes with sex-specific effects </a> <p class="publication_item__authors"> Randy Strong, Richard A. Miller, Molly Bogue, Elizabeth Fernandez, Martin A. Javors, Sergiy Libert, Paul Anthony Marinez, Michael P. Murphy, Nicolas Musi, James F. Nelson, Michael Petrascheck, Peter Reifsnyder, Arlan Richardson, Adam B. Salmon, Francesca Macchiarini, and David E. Harrison </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.nature.com/articles/s41514-020-00051-6 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://www.nature.com/articles/s41514-020-00051-6 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.nature.com/articles/s41514-020-00051-6 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.nature.com/articles/s41514-020-00051-6 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 11.19.2020 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> NPJ Aging and Mechanisms of Disease </span> </div> <a href="https://www.nature.com/articles/s41514-020-00051-6" target="_self" class="t-list-label"> NQO1 protects obese mice through improvements in glucose and lipid metabolism </a> <p class="publication_item__authors"> Andrea Di Francesco, Youngshim Choi, Michel Bernier, Yingchun Zhang, Alberto Diaz-Ruiz, Miguel A. Aon, Krystle Kalafut, Margaux R. Ehrlich, Kelsey Murt, Ahmed Ali, Kevin J. Pearson, Sophie Levan, Joshua D. Preston, Alejandro Martin-Montalvo, Jennifer L. Martindale, Kotb Abdelmohsen, Cole R. Michel, Diana M. Willmes, Christine Henke, Placido Navas, Jose Manuel Villalba, David Siegel, Myriam Gorospe, Kristofer Fritz, Shyam Biswal, David Ross and Rafael de Cabo </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.nature.com/articles/s41586-020-2922-4 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://www.nature.com/articles/s41586-020-2922-4 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.nature.com/articles/s41586-020-2922-4 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.nature.com/articles/s41586-020-2922-4 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 11.18.2020 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Nature </span> </div> <a href="https://www.nature.com/articles/s41586-020-2922-4" target="_self" class="t-list-label"> A molecular cell atlas of the human lung from single-cell RNA sequencing </a> <p class="publication_item__authors"> Kyle J. Travaglini, Ahmad N. Nabhan, Lolita Penland, Rahul Sinha, Astrid Gillich, Rene V. Sit, Stephen Chang, Stephanie D. Conley, Yasuo Mori, Jun Seita, Gerald J. Berry, Joseph B. Shrager, Ross J. Metzger, Christin S. Kuo, Norma Neff, Irving L. Weissman, Stephen R. Quake and Mark A. Krasnow </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://elifesciences.org/articles/59201 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" 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1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://elifesciences.org/articles/59201 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://elifesciences.org/articles/59201 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 11.12.2020 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> eLife </span> </div> <a href="https://elifesciences.org/articles/59201" target="_self" class="t-list-label"> A rat epigenetic clock recapitulates phenotypic aging and co-localizes with heterochromatin </a> <p class="publication_item__authors"> Morgan Levine, Ross A McDevitt, Margarita Meer, Kathy Perdue, Andrea Di Francesco, Theresa Meade, Colin Farrell, Kyra Thrush, Meng Wang, Christopher Dunn, Matteo Pellegrini, Rafael de Cabo and Luigi Ferrucci </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://elifesciences.org/articles/57681 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle 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2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://elifesciences.org/articles/57681 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://elifesciences.org/articles/57681 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 11.12.2020 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> eLife </span> </div> <a href="https://elifesciences.org/articles/57681" target="_self" class="t-list-label"> A versatile oblique plane microscope for large-scale and high-resolution imaging of subcellular dynamics </a> <p class="publication_item__authors"> Etai Sapoznik, Bo-Jui Chang, Jaewon Huh, Robert J Ju, Evgenia V Azarova, Theresa Pohlkamp, Erik S Welf, David Broadbent, Alexandre F Carisey, Samantha J Stehbens, Kyung-Min Lee, Arnaldo Marín, Ariella B Hanker, Jens C Schmidt, Carlos L Arteaga, Bin Yang, Yoshihiko Kobayashi, Purushothama Rao Tata, Rory Kruithoff, Konstantin Doubrovinski, Douglas P Shepherd, Alfred Millett-Sikking, Andrew G York, Kevin M Dean and Reto P Fiolka </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a 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0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://academic.oup.com/genetics/article/216/2/261/6066179?login=false "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://academic.oup.com/genetics/article/216/2/261/6066179?login=false "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 10.21.2020 </span> <span class="post-type" data-slug="commentaries-reviews"> Commentaries & Reviews </span> <span class="journal"> Genetics </span> </div> <a href="https://academic.oup.com/genetics/article/216/2/261/6066179?login=false" target="_self" class="t-list-label"> Perspective: Linkage Maps, Communities of Geneticists, and Genome Databases </a> <p class="publication_item__authors"> David Botstein </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.nature.com/articles/s41592-020-0965-y "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://www.nature.com/articles/s41592-020-0965-y "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.nature.com/articles/s41592-020-0965-y "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.nature.com/articles/s41592-020-0965-y "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 10.12.2020 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Nature Methods </span> </div> <a href="https://www.nature.com/articles/s41592-020-0965-y" target="_self" class="t-list-label"> A systematic evaluation of the design and context dependencies of massively parallel reporter assays </a> <p class="publication_item__authors"> Jason C. Klein, Vikram Agarwal, Fumitaka Inoue, Aidan Keith, Beth Martin, Martin Kircher, Nadav Ahituv and Jay Shendure </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.nature.com/articles/s41592-020-0958-x "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://www.nature.com/articles/s41592-020-0958-x "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.nature.com/articles/s41592-020-0958-x "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.nature.com/articles/s41592-020-0958-x "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 10.12.2020 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Nature Methods </span> </div> <a href="https://www.nature.com/articles/s41592-020-0958-x" target="_self" class="t-list-label"> Predicting 3D genome folding from DNA sequence with Akita </a> <p class="publication_item__authors"> Geoff Fudenberg, David R. Kelley and Katherine S. Pollard </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.g3journal.org/content/10/10/3623 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" 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1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.g3journal.org/content/10/10/3623 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.g3journal.org/content/10/10/3623 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 10.01.2020 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> G3 </span> </div> <a href="https://www.g3journal.org/content/10/10/3623" target="_self" class="t-list-label"> Application of Transcriptional Gene Modules to Analysis of Caenorhabditis elegans’ Gene Expression Data </a> <p class="publication_item__authors"> Michael Cary, Katie Podshivalova and Cynthia Kenyon </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.nature.com/articles/s41467-020-18515-4 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://www.nature.com/articles/s41467-020-18515-4 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 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<svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 09.17.2020 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Nature Communications </span> </div> <a href="https://www.nature.com/articles/s41467-020-18515-4" target="_self" class="t-list-label"> Evaluating the informativeness of deep learning annotations for human complex diseases </a> <p class="publication_item__authors"> Kushal K Dey, Bryce van de Geijn, Samuel Sungil Kim, Farhad Hormozdiari, David R Kelley and Alkes L Price </p> </div> </article> <article class="publication_item from-bottom__0"> <div 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1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 09.02.2020 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> G3 (Bethesda) </span> </div> <a href="https://academic.oup.com/g3journal/article/10/9/2911/6060118?login=false" target="_self" class="t-list-label"> Fully Phased Sequence of a Diploid Human Genome Determined de Novo from the DNA of a Single Individual </a> <p class="publication_item__authors"> Llya Soifer, Nicole L Fong, Nelda Yi, Andrea T Ireland, Irene Lam, Matthew Sooknah, Jonathan S Paw, Paul Peluso, Gregory T Concepcion, David Rank, Alex R Hastie, Vladimir Jojic, J Graham Ruby, David Botstein and Margaret A Roy </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" 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.243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.liebertpub.com/doi/10.1089/cmb.2019.0340 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.liebertpub.com/doi/10.1089/cmb.2019.0340 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 08.27.2020 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Journal of Computational Biology </span> </div> <a href="https://www.liebertpub.com/doi/10.1089/cmb.2019.0340" target="_self" class="t-list-label"> Modeling Multiplexed Images with Spatial-LDA Reveals Novel Tissue Microenvironments </a> <p class="publication_item__authors"> Zhenghao Chen, Ilya Soifer, Hugo Hilton, Leeat Keren and Vladimir Jojic </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.mdpi.com/2409-9279/3/3/54 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://www.mdpi.com/2409-9279/3/3/54 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.mdpi.com/2409-9279/3/3/54 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 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1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 07.30.2020 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Methods Protoc </span> </div> <a href="https://www.mdpi.com/2409-9279/3/3/54" target="_self" class="t-list-label"> IsoSearch: An Untargeted and Unbiased Metabolite and Lipid Isotopomer Tracing Strategy from HR-LC-MS/MS Datasets </a> <p class="publication_item__authors"> He Huang, Min Yuan, Phillip Seitzer, Susan Ludwigsen and John M. Asara </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1008050 "> <svg height="30" viewBox="0 0 30 30" 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3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1008050 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 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1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 07.20.2020 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> PLoS Computational Biology </span> </div> <a href="https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1008050" target="_self" class="t-list-label"> Cross-species regulatory sequence activity prediction </a> <p class="publication_item__authors"> David R Kelley </p> </div> </article> <article 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href="mailto:?body=https://www.nature.com/articles/s41596-020-00422-z "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 07.08.2020 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Nature Protocols </span> </div> <a href="https://www.nature.com/articles/s41596-020-00422-z" target="_self" class="t-list-label"> lentiMPRA and MPRAflow for high-throughput functional characterization of gene regulatory elements </a> <p class="publication_item__authors"> M. Grace Gordon, Fumitaka Inoue, Beth Martin, Max Schubach, Vikram Agarwal, Sean Whalen, Shiyun Feng, Jingjing Zhao, Tal Ashuach, Ryan Ziffra, Anat Kreimer, Ilias Georgakopoulos-Soares, Nir Yosef, Chun Jimmie Ye, Katherine S. Pollard, Jay Shendure, Martin Kircher and Nadav Ahituv </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.nature.com/articles/s41586-020-2453-z "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://www.nature.com/articles/s41586-020-2453-z "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.nature.com/articles/s41586-020-2453-z "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.nature.com/articles/s41586-020-2453-z "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 07.01.2020 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Nature </span> </div> <a href="https://www.nature.com/articles/s41586-020-2453-z" target="_self" class="t-list-label"> Physiological blood-brain transport is impaired with age by a shift in transcytosis </a> <p class="publication_item__authors"> Andrew C. Yang, Marc Y. Stevens, Michelle B. Chen, Davis P. Lee, Daniel Stähli, David Gate, Kévin Contrepois, Winnie Chen, Tal Iram, Lichao Zhang, Ryan T. Vest, Aisling Chaney, Benoit Lehallier, Niclas Olsson, Haley du Bois, Ryan Hsieh, Haley C. Cropper, Daniela Berdnik, Lulin Li, Elizabeth Y. Wang, Gavin M. Traber, Carolyn R. Bertozzi, Jian Luo, Michael P. Snyder, Joshua E. Elias, Stephen R. Quake, Michelle L. James and Tony Wyss-Coray </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" 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class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 06.26.2020 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Cell Systems </span> </div> <a href="https://www.cell.com/cell-systems/fulltext/S2405-4712(20)30195-2?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2405471220301952%3Fshowall%3Dtrue" target="_self" class="t-list-label"> Solo: Doublet Identification in Single-Cell RNA-Seq via Semi-Supervised Deep Learning </a> <p class="publication_item__authors"> Nicholas J Bernstein, Nicole L Fong, Irene Lam, Margaret A Roy, David G Hendrickson, David R Kelley </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" 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</div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 06.23.2020 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Aging </span> </div> <a href="https://www.aging-us.com/article/103534/text" target="_self" class="t-list-label"> The mitochondrial derived peptide humanin is a regulator of lifespan and healthspan </a> <p class="publication_item__authors"> Kelvin Yen, Hemal H Mehta, Su-Jeong Kim, YanHe Lue, James Hoang, Noel Guerrero, Jenna Port, Qiuli Bi, Gerardo Navarrete, Sebastian Brandhorst, Kaitlyn Noel Lewis, Junxiang Wan, Ronald Swerdloff, Julie A Mattison, Rochelle Buffenstein, Carrie V Breton, Christina Wang, Valter Longo, Gil Atzmon, Douglas Wallace, Nir Barzilai and Pinchas Cohen </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div 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fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 06.04.2020 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Nature Communications </span> </div> <a href="https://www.nature.com/articles/s41467-020-16348-9" target="_self" class="t-list-label"> SIRT1 accelerates the progression of activity-based anorexia </a> <p class="publication_item__authors"> Timothy M. Robinette, Justin W. Nicholatos, Adam B. Francisco, Kayla E. Brooks, Rachel Y. Diao, Sandro Sorbi, Valdo Ricca, Benedetta Nacmias, Miguel A. Brieño-Enríquez and Sergiy Libert </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.nature.com/articles/s41467-020-16358-7 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://www.nature.com/articles/s41467-020-16358-7 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.nature.com/articles/s41467-020-16358-7 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.nature.com/articles/s41467-020-16358-7 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 06.03.2020 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Nature Communications </span> </div> <a href="https://www.nature.com/articles/s41467-020-16358-7" target="_self" class="t-list-label"> Independent regulation of age associated fat accumulation and longevity </a> <p class="publication_item__authors"> Anthony O. Beas, Patricia B. Gordon, Clara L. Prentiss, Carissa Perez Olsen, Matthew A. Kukurugya, Bryson D. Bennett, Susan M. Parkhurst and Daniel E. Gottschling </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0233779 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0233779 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0233779 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0233779 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 05.29.2020 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> PLoS One </span> </div> <a href="https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0233779" target="_self" class="t-list-label"> A tps1Δ persister-like state in Saccharomyces cerevisiae is regulated by MKT1 </a> <p class="publication_item__authors"> Patrick A. Gibney, Anqi Chen, Ariel Schieler, Jonathan C. Chen, Yifan Xu, David G. Hendrickson, R. Scott McIsaac, Joshua D. Rabinowitz and David Botstein </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.embopress.org/doi/full/10.15252/msb.20199167 "> <svg height="30" viewBox="0 0 30 30" 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1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.embopress.org/doi/full/10.15252/msb.20199167 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 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0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 05.20.2020 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Molecular Systems Biology </span> </div> <a href="https://www.embopress.org/doi/full/10.15252/msb.20199167" target="_self" class="t-list-label"> Genetic interaction profiles of regulatory kinases differ between environmental conditions and cellular states </a> <p class="publication_item__authors"> Siyu Sun, Anastasia Baryshnikova, Nathan Brandt and David Gresham </p> </div> </article> 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class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 05.19.2020 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Cell Reports </span> </div> <a href="https://www.cell.com/cell-reports/fulltext/S2211-1247(20)30616-1?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2211124720306161%3Fshowall%3Dtrue" target="_self" class="t-list-label"> Predicting mRNA Abundance Directly from Genomic Sequence Using Deep Convolutional Neural Networks </a> <p class="publication_item__authors"> Vikram Agarwal and Jay Shendure </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" 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</div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 04.28.2020 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> PNAS </span> </div> <a href="https://www.pnas.org/doi/full/10.1073/pnas.1917608117" target="_self" class="t-list-label"> Development of a therapeutic anti-HtrA1 antibody and the identification of DKK3 as a pharmacodynamic biomarker in geographic atrophy </a> <p class="publication_item__authors"> Irene Tom, Victoria C Pham, Kenneth J Katschke Jr, Wei Li, Wei-Ching Liang, Johnny Gutierrez, Andrew Ah Young, Isabel Figueroa, Shadi Toghi Eshghi, ChingWei V Lee, Jitendra Kanodia, Scott J Snipas, Guy S Salvesen, Phillip Lai, Lee Honigberg, Menno van Lookeren Campagne, Daniel Kirchhofer, Amos Baruch and Jennie R Lill </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div 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href="mailto:?body=https://www.nature.com/articles/s41598-020-64009-0 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 04.24.2020 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Scientific Reports </span> </div> <a href="https://www.nature.com/articles/s41598-020-64009-0" target="_self" class="t-list-label"> Unprovoked Stabilization and Nuclear Accumulation of the Naked Mole-Rat p53 Protein </a> <p class="publication_item__authors"> Marian M. Deuker, Kaitlyn N. Lewis, Maria Ingaramo, Jacob Kimmel, Rochelle Buffenstein and Jeff Settleman </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.nature.com/articles/s41598-020-63669-2 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://www.nature.com/articles/s41598-020-63669-2 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.nature.com/articles/s41598-020-63669-2 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.nature.com/articles/s41598-020-63669-2 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 04.22.2020 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Scientific Reports </span> </div> <a href="https://www.nature.com/articles/s41598-020-63669-2" target="_self" class="t-list-label"> CRISPR-mediated gene targeting of CK1δ/ε leads to enhanced understanding of their role in endocytosis via phosphoregulation of GAPVD1 </a> <p class="publication_item__authors"> Rodrigo X. Guillen, Janel R. Beckley, Jun-Song Chen and Kathleen L. Gould </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://opg.optica.org/boe/fulltext.cfm?uri=boe-11-5-2313&id=429698 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://opg.optica.org/boe/fulltext.cfm?uri=boe-11-5-2313&id=429698 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://opg.optica.org/boe/fulltext.cfm?uri=boe-11-5-2313&id=429698 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://opg.optica.org/boe/fulltext.cfm?uri=boe-11-5-2313&id=429698 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 04.02.2020 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Biomed Opt Express </span> </div> <a href="https://opg.optica.org/boe/fulltext.cfm?uri=boe-11-5-2313&id=429698" target="_self" class="t-list-label"> Predicting resolution and image quality in RESOLFT and other point scanning microscopes </a> <p class="publication_item__authors"> Andreas Bodén, Xavier Casas Moreno, Benjamin K. Cooper, Andrew G. York and Ilaria Testa </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.embopress.org/doi/10.15252/msb.20199174 "> <svg height="30" viewBox="0 0 30 30" width="30"><g 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0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.embopress.org/doi/10.15252/msb.20199174 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.embopress.org/doi/10.15252/msb.20199174 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 03.17.2020 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Molecular Systems Biology </span> </div> <a href="https://www.embopress.org/doi/10.15252/msb.20199174" target="_self" class="t-list-label"> Learning causal networks using inducible transcription factors and transcriptome‐wide time series </a> <p class="publication_item__authors"> Hackett S, Baltz E, Coram M, Wranik B, Kim G, Baker A, Fan M, Hendrickson D, Berndl M, McIsaac R. </p> </div> </article> <article 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0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 02.25.2020 </span> <span class="post-type" data-slug="commentaries-reviews"> Commentaries & Reviews </span> <span class="journal"> The FEBS Journal </span> </div> <a href="https://febs.onlinelibrary.wiley.com/doi/10.1111/febs.15261" target="_self" class="t-list-label"> Data libraries: the missing element for modeling biological systems </a> <p class="publication_item__authors"> Anastasia Baryshnikova </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div 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0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 02.07.2020 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> PLoS Genetics </span> </div> <a href="https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1008597" target="_self" class="t-list-label"> Skp, Cullin, F-box (SCF)-Met30 and SCF-Cdc4-Mediated Proteolysis of CENP-A Prevents Mislocalization of CENP-A for Chromosomal Stability in Budding Yeast </a> <p class="publication_item__authors"> Wei-Chun Au, Tianyi Zhang, Prashant K Mishra, Jessica R Eisenstatt, Robert L Walker, Josefina Ocampo, Anthony Dawson, Jack Warren, Michael Costanzo, Anastasia Baryshnikova, Karin Flick, David J Clark, Paul S Meltzer, Richard E Baker, Chad Myers, Charles Boone, Peter Kaiser and Munira A Basrai </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a 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.677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 02.03.2020 </span> <span class="post-type" data-slug="commentaries-reviews"> Commentaries & Reviews </span> <span class="journal"> JCI </span> </div> <a href="https://www.jci.org/articles/view/129196" target="_self" class="t-list-label"> The promise and reality of therapeutic discovery from large cohorts </a> <p class="publication_item__authors"> Eugene Melamud, D Leland Taylor, Anurag Sethi, Madeleine Cule, Anastasia Baryshnikova, Danish Saleheen, Nick van Bruggen and Garret A FitzGerald </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a 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class="t-list-label"> Stress Resistance Screen in a Human Primary Cell Line Identifies Small Molecules That Affect Aging Pathways and Extend Caenorhabditis elegans’ Lifespan </a> <p class="publication_item__authors"> Peichuan Zhang, Yuying Zhai, James Cregg, Kenny Kean-Hooi Ang, Michelle Arkin and Cynthia Kenyon </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 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4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 01.19.2020 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Molecular Ecology </span> </div> <a href="https://onlinelibrary.wiley.com/doi/10.1111/mec.15346" target="_self" class="t-list-label"> Transitions in paternal social status predict patterns of offspring growth and metabolic transcription </a> <p class="publication_item__authors"> Joseph W. 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High-Dose Selection Scheme Reveals Distinct Mechanisms of Acquired Resistance to Oncogenic Kinase Inhibition in Cancer Cells </a> <p class="publication_item__authors"> Kenneth J. Finn, Scott E. Martin and Jeff Settleman </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3000528 "> <svg height="30" viewBox="0 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2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3000528 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 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1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 11.21.2019 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> PLoS Biology </span> </div> <a href="https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3000528" target="_self" class="t-list-label"> Single-cell transcriptomics of the naked mole-rat reveals unexpected features of mammalian immunity </a> <p class="publication_item__authors"> Hilton H, Rubinstein N, Janki P, Ireland A, Bernstein N, Fong N, Wright K, Smith M, Finkle D, Martin-McNulty B, Roy M, Imai D, Jojic V, Buffenstein R. </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" 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3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://genome.cshlp.org/content/29/12/2088.short "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://genome.cshlp.org/content/29/12/2088.short "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 11.21.2019 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Genome Research </span> </div> <a href="https://genome.cshlp.org/content/29/12/2088.short" target="_self" class="t-list-label"> Murine single-cell RNA-seq reveals cell-identity- and tissue-specific trajectories of aging </a> <p class="publication_item__authors"> Kimmel J, Penland L, Rubinstein N, Hendrickson D, Kelley D, Rosenthal A </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://academic.oup.com/g3journal/article/9/9/2863/6026390 "> <svg 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2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://academic.oup.com/g3journal/article/9/9/2863/6026390 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 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1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 09.01.2019 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> G3 </span> </div> <a href="https://academic.oup.com/g3journal/article/9/9/2863/6026390" target="_self" class="t-list-label"> A prospective analysis of genetic variants associated with human lifespan </a> <p class="publication_item__authors"> Wright K, Rand K, Kermany A, Noto K, Curtis D, Garrigan D, Slinkov D, Dorfman I, Granka J, Byrnes J, Myres N, Ball C, Ruby G. </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://elifesciences.org/articles/47362 "> <svg height="30" viewBox="0 0 30 30" 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0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://elifesciences.org/articles/47362 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://elifesciences.org/articles/47362 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 08.27.2019 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> eLife </span> </div> <a href="https://elifesciences.org/articles/47362" target="_self" class="t-list-label"> Systematic identification of cancer cell vulnerabilities to natural killer cell-mediated immune surveillance </a> <p class="publication_item__authors"> Pech M, Fong L, Villalta J, Chan L, Kharbanda S, O’Brien J, McAllister F, Firestone A, Jan C and Settleman J. </p> </div> </article> <article class="publication_item from-bottom__0"> <div 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stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-019-5629-x "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-019-5629-x "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-019-5629-x "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 07.23.2019 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> BMC </span> </div> <a href="https://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-019-5629-x" target="_self" class="t-list-label"> The lichen symbiosis re-viewed through the genomes of Cladonia grayi and its algal partner Asterochloris glomerata </a> <p class="publication_item__authors"> Daniele Armaleo, Olaf Müller, François Lutzoni, Ólafur S Andrésson, Guillaume Blanc, Helge B Bode, Frank R Collart, Francesco Dal Grande, Fred Dietrich, Igor V Grigoriev, Suzanne Joneson, Alan Kuo, Peter E Larsen, John M Logsdon Jr, David Lopez, Francis Martin, Susan P May, Tami R McDonald, Sabeeha S Merchant, Vivian Miao, Emmanuelle Morin, Ryoko Oono, Matteo Pellegrini, Nimrod Rubinstein, Maria Virginia Sanchez-Puerta, Elizabeth Savelkoul, Imke Schmitt, Jason C Slot, Darren Soanes, Péter Szövényi, Nicholas J Talbot, Claire Veneault-Fourrey and Basil B Xavier </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://elifesciences.org/articles/45506 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://elifesciences.org/articles/45506 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://elifesciences.org/articles/45506 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://elifesciences.org/articles/45506 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 06.07.2019 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> eLIFE </span> </div> <a href="https://elifesciences.org/articles/45506" target="_self" class="t-list-label"> Cooperation of mitochondrial and ER factors in quality control of tail-anchored proteins </a> <p class="publication_item__authors"> Verena Dederer, Anton Khmelinskii, Anna Gesine Huhn, Voytek Okreglak, Michael Knop and Marius K Lemberg </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 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5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.molbiolcell.org/doi/10.1091/mbc.E19-02-0094 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 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4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 05.29.2019 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Molecular Biology of the Cell </span> </div> <a href="https://www.molbiolcell.org/doi/10.1091/mbc.E19-02-0094" target="_self" class="t-list-label"> Rsp5 and Mdm30 reshape the mitochondrial network in response to age-induced vacuole stress </a> <p class="publication_item__authors"> Jenna M Goodrum, Austin R Lever, Troy K Coody, Daniel E Gottschling and Adam L Hughes </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div 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1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6752884/ "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 04.12.2019 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Proc Mach Learn Res </span> </div> <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6752884/" target="_self" class="t-list-label"> Inferring Multidimensional Rates of Aging from Cross-Sectional Data </a> <p class="publication_item__authors"> Emma Pierson, Pang Wei Koh, Tatsunori Hashimoto, Daphne Koller, Jure Leskovec, Nicholas Eriksson and Percy Liang </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" 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10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.cell.com/cell-systems/fulltext/S2405-4712(19)30039-0 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 03.13.2019 </span> <span class="post-type" data-slug="commentaries-reviews"> Commentaries & Reviews </span> <span class="journal"> Cell Systems </span> </div> <a href="https://www.cell.com/cell-systems/fulltext/S2405-4712(19)30039-0" target="_self" class="t-list-label"> Untangling Aging Using Dynamic, Organism-Level Phenotypic Networks </a> <p class="publication_item__authors"> Freund A. </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" 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1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.science.org/doi/10.1126/science.aar2038 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 03.07.2019 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Science </span> </div> <a href="https://www.science.org/doi/10.1126/science.aar2038" target="_self" class="t-list-label"> Evidence for hormonal control of heart regenerative capacity during endothermy acquisition </a> <p class="publication_item__authors"> Kentaro Hirose, Alexander Y Payumo, Stephen Cutie, Alison Hoang, Hao Zhang, Romain Guyot, Dominic Lunn, Rachel B Bigley, Hongyao Yu, Jiajia Wang, Megan Smith, Ellen Gillett, Sandra E Muroy, Tobias Schmid, Emily Wilson, Kenneth A Field, DeeAnn M Reeder, Malcom Maden, Michael M Yartsev, Michael J Wolfgang, Frank Grützner, Thomas S Scanlan, Luke I Szweda, Rochelle Buffenstein, Guang Hu, Frederic Flamant, Jeffrey E Olgin and Guo N Huang </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.nature.com/articles/s42255-018-0023-6 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://www.nature.com/articles/s42255-018-0023-6 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" 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12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.nature.com/articles/s42255-018-0023-6 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 03.04.2019 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Nature Metabolism </span> </div> <a href="https://www.nature.com/articles/s42255-018-0023-6" target="_self" class="t-list-label"> MANF regulates metabolic and immune homeostasis in ageing and protects against liver damage </a> <p class="publication_item__authors"> Pedro Sousa-Victor, Joana Neves, Wendy Cedron-Craft, P Britten Ventura, Chen-Yu Liao, Rebeccah R Riley, Ilya Soifer, Nicholas van Bruggen, Ganesh A Kolumam, Saul A Villeda, Deepak A Lamba and Heinrich Jasper </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.nature.com/articles/s41467-019-08393-w "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://www.nature.com/articles/s41467-019-08393-w "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" 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d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.nature.com/articles/s41467-019-08393-w "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 01.31.2019 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Nature Communications </span> </div> <a href="https://www.nature.com/articles/s41467-019-08393-w" target="_self" class="t-list-label"> Functional role of PGAM5 multimeric assemblies and their polymerization into filaments </a> <p class="publication_item__authors"> Karen Ruiz, Tarjani M Thaker, Christopher Agnew, Lakshmi Miller-Vedam, Raphael Trenker, Clara Herrera, Maria Ingaramo, Daniel Toso, Adam Frost and Natalia Jura </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://elifesciences.org/articles/42940 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://elifesciences.org/articles/42940 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" 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stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://elifesciences.org/articles/42940 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 01.09.2019 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> eLife </span> </div> <a href="https://elifesciences.org/articles/42940" target="_self" class="t-list-label"> eIF2B activator prevents neurological defects caused by a chronic integrated stress response </a> <p class="publication_item__authors"> Wong Y, LeBon L, Basso A, Kohlhaas K, Nikkel A, Robb H, Donnelly-Roberts D, Prakash J, Swensen A, Rubinstein N, Krishnan S, McAllister F, Haste N, O’Brien J, Roy M, Ireland A, Frost J, Shi L, Riedmaier S, Martin K, Dart M, Sidrauski C </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" 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href="mailto:?body=https://www.cell.com/cell-reports/fulltext/S2211-1247(18)31878-3?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2211124718318783%3Fshowall%3Dtrue "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 12.18.2018 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Cell Reports </span> </div> <a href="https://www.cell.com/cell-reports/fulltext/S2211-1247(18)31878-3?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2211124718318783%3Fshowall%3Dtrue" target="_self" class="t-list-label"> A Visual Framework for Classifying Determinants of Cell Size </a> <p class="publication_item__authors"> Felix Jonas, Ilya Soifer and Naama Barkai </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" 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10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://link.springer.com/protocol/10.1007/978-1-4939-8618-7_12 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 11.13.2018 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Computational Cell Biology </span> </div> <a href="https://link.springer.com/protocol/10.1007/978-1-4939-8618-7_12" target="_self" class="t-list-label"> Spatial Analysis of Functional Enrichment (SAFE) in Large Biological Networks </a> <p class="publication_item__authors"> Anastasia Baryshnikova </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" 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.677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 11.13.2018 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Methods in Molecular Biology </span> </div> <a href="https://link.springer.com/protocol/10.1007/978-1-4939-8618-7_15" target="_self" class="t-list-label"> Simultaneous Profiling of DNA Accessibility and Gene Expression Dynamics with ATAC-Seq and RNA-Seq </a> <p class="publication_item__authors"> David G Hendrickson, Ilya Soifer, Bernd J Wranik, David Botstein and R Scott McIsaac </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a 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10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.nature.com/articles/s41467-018-07109-w "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 11.08.2018 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Nat Communications </span> </div> <a href="https://www.nature.com/articles/s41467-018-07109-w" target="_self" class="t-list-label"> HLA-B57 micropolymorphism defines the sequence and conformational breadth of the immunopeptidome </a> <p class="publication_item__authors"> Patricia T. Illing, Phillip Pymm, Nathan P. Croft, Hugo G. Hilton, Vladimir Jojic, Alex S. Han, Juan L. Mendoza, Nicole A. Mifsud, Nadine L. Dudek, James McCluskey, Peter Parham, Jamie Rossjohn, Julian P. Vivian and Anthony W. Purcell </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=http://www.genetics.org/content/210/3/1109 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" 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1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=http://www.genetics.org/content/210/3/1109 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=http://www.genetics.org/content/210/3/1109 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 11.01.2018 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Genetics </span> </div> <a href="http://www.genetics.org/content/210/3/1109" target="_self" class="t-list-label"> Estimates of the heritability of human longevity are substantially inflated due to assortative mating. </a> <p class="publication_item__authors"> Ruby G, Wright K, Rand K, Kermany A, Noto K, Curtis D, Varner N, Garrigan D, Slinkov D, Dorfman I, Granka J, Byrnes, J, Myres N, Ball C. </p> </div> </article> <article class="publication_item 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2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://stemcellres.biomedcentral.com/articles/10.1186/s13287-018-1027-6 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" 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1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 10.31.2018 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Stem Cell Research & Therapy </span> </div> <a href="https://stemcellres.biomedcentral.com/articles/10.1186/s13287-018-1027-6" target="_self" class="t-list-label"> Identifying deer antler uhrf1 proliferation and s100a10 mineralization genes using comparative RNA-seq </a> <p class="publication_item__authors"> Dai Fei Elmer Ker, Dan Wang, Rashmi Sharma, Bin Zhang, Ben Passarelli, Norma Neff, Chunyi Li, William Maloney, Stephen Quake and Yunzhi Peter Yang </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://link.springer.com/protocol/10.1007/978-1-4939-8879-2_6 "> <svg height="30" viewBox="0 0 30 30" 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0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 10.31.2018 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Methods in Molecular Biology </span> </div> <a href="https://link.springer.com/protocol/10.1007/978-1-4939-8879-2_6" target="_self" class="t-list-label"> Spheroid Culture of Human Pancreatic Ductal Cells to Reconstitute Development of Pancreatic Intraepithelial Neoplasia </a> <p class="publication_item__authors"> James J. Lee and Seung K. Kim </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://elifesciences.org/articles/39911 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" 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1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://elifesciences.org/articles/39911 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://elifesciences.org/articles/39911 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 10.18.2018 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> eLife </span> </div> <a href="https://elifesciences.org/articles/39911" target="_self" class="t-list-label"> A new experimental platform facilitates assessment of the transcriptional and chromatin landscapes of aging yeast </a> <p class="publication_item__authors"> Hendrickson D, Soifer I, Wranik B, Kim G, Robles M, Gibney P, McIsaac S. </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.nature.com/articles/s41592-018-0112-1 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://www.nature.com/articles/s41592-018-0112-1 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.nature.com/articles/s41592-018-0112-1 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.nature.com/articles/s41592-018-0112-1 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 08.31.2018 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Nature Methods </span> </div> <a href="https://www.nature.com/articles/s41592-018-0112-1" target="_self" class="t-list-label"> An open-source platform for analyzing and sharing worm-behavior data </a> <p class="publication_item__authors"> Avelino Javer, Michael Currie, Chee Wai Lee, Jim Hokanson, Kezhi Li, Céline N Martineau, Eviatar Yemini, Laura J Grundy, Chris Li, QueeLim Ch’ng, William R Schafer, Ellen A A Nollen, Rex Kerr and André E X Brown </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" 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class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 08.14.2018 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Cell Reports </span> </div> <a href="https://www.cell.com/cell-reports/fulltext/S2211-1247(18)31144-6?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2211124718311446%3Fshowall%3Dtrue" target="_self" class="t-list-label"> Enhancer Activity Requires CBP/P300 Bromodomain-Dependent Histone H3K27 Acetylation </a> <p class="publication_item__authors"> Ryan Raisner, Samir Kharbanda, Lingyan Jin, Edwin Jeng, Emily Chan, Mark Merchant, Peter M Haverty, Russell Bainer, Tommy Cheung, David Arnott, E Megan Flynn, F Anthony Romero, Steven Magnuson and Karen E Gascoigne </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div 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</div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 05.28.2018 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Experimental Dermatology </span> </div> <a href="https://onlinelibrary.wiley.com/doi/10.1111/exd.13694" target="_self" class="t-list-label"> Analysis of gene expression profiles of multiple skin diseases identifies a conserved signature of disrupted homeostasis </a> <p class="publication_item__authors"> Kevin J. Mills, Michael K. Robinson, Joseph D. Sherrill, Daniel J. Schnell and Jun Xu </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964061/ "> <svg height="30" viewBox="0 0 30 30" width="30"><g 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0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964061/ "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964061/ "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 04.20.2018 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Geroscience </span> </div> <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964061/" target="_self" class="t-list-label"> A window into extreme longevity; the circulating metabolomic signature of the naked mole-rat, a mammal that shows negligible senescence. </a> <p class="publication_item__authors"> Lewis KN, Rubinstein ND, Buffenstein R. </p> </div> </article> <article class="publication_item from-bottom__0"> <div 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1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.molbiolcell.org/doi/10.1091/mbc.E17-11-0666 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.molbiolcell.org/doi/10.1091/mbc.E17-11-0666 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 04.18.2018 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Molecular Biolology of the Cell </span> </div> <a href="https://www.molbiolcell.org/doi/10.1091/mbc.E17-11-0666" target="_self" class="t-list-label"> Common and divergent features of galactose-1-phosphate and fructose-1-phosphate toxicity in yeast </a> <p class="publication_item__authors"> Gibney PA, Schieler A, Chen JC, Bacha-Hummel JM, Botstein M, Volpe M, Silverman SJ, Xu Y, Bennett BD, Rabinowitz JD, Botstein D. </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://genome.cshlp.org/content/28/5/739 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://genome.cshlp.org/content/28/5/739 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://genome.cshlp.org/content/28/5/739 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://genome.cshlp.org/content/28/5/739 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 03.27.2018 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Genome Research </span> </div> <a href="https://genome.cshlp.org/content/28/5/739" target="_self" class="t-list-label"> Sequential regulatory activity prediction across chromosomes with convolutional neural networks </a> <p class="publication_item__authors"> David R Kelley, Yakir A Reshef, Maxwell Bileschi, David Belanger, Cory Y McLean and Jasper Snoek </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829914/ "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829914/ "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829914/ "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829914/ "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 02.28.2018 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> eLife </span> </div> <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829914/" target="_self" class="t-list-label"> The small molecule ISRIB rescues the stability and activity of Vanishing White Matter Disease eIF2B mutant complexes. </a> <p class="publication_item__authors"> Wong YL, LeBon L, Edalji R, Lim HB, Sun C, Sidrauski C. </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div 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1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 02.08.2018 </span> <span class="post-type" data-slug="commentaries-reviews"> Commentaries & Reviews </span> <span class="journal"> elife </span> </div> <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5805407/" target="_self" class="t-list-label"> Challenges in validating candidate therapeutic targets in cancer </a> <p class="publication_item__authors"> Settleman J, Sawyers CL, Hunter T. </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div 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4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 02.01.2018 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Cell </span> </div> <a href="https://www.cell.com/cell/fulltext/S0092-8674(18)30002-3?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867418300023%3Fshowall%3Dtrue" target="_self" class="t-list-label"> Dynamic Ligand Discrimination in the Notch Signaling Pathway </a> <p class="publication_item__authors"> Nagarajan Nandagopal, Leah A Santat, Lauren LeBon, David Sprinzak, Marianne E Bronner and Michael B Elowitz </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" 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12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://elifesciences.org/articles/31157 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 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href="https://elifesciences.org/articles/31157" target="_self" class="t-list-label"> Naked mole-rat mortality rates defy Gompertzian laws by not increasing with age </a> <p class="publication_item__authors"> Ruby JG, Smith M, Buffenstein R. </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div 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1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 01.22.2018 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Developmental Cell </span> </div> <a href="https://www.cell.com/developmental-cell/fulltext/S1534-5807(17)30984-X?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS153458071730984X%3Fshowall%3Dtrue" target="_self" class="t-list-label"> Lipid Homeostasis Is Maintained by Dual Targeting of the Mitochondrial PE Biosynthesis Enzyme to the ER </a> <p class="publication_item__authors"> Jonathan R Friedman, Muthukumar Kannan, Alexandre Toulmay, Calvin H Jan, Jonathan S Weissman, William A Prinz and Jodi Nunnari </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a 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10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5936623/ "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 11.30.2017 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Nature </span> </div> <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5936623/" target="_self" class="t-list-label"> A lysosomal switch triggers proteostasis renewal in the immortal C. elegans germ lineage </a> <p class="publication_item__authors"> Bohnert KA, Kenyon C. </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" 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1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://rupress.org/jcb/article/217/1/79/54862/Stem-cells-Aging-and-transcriptional "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 10.25.2017 </span> <span class="post-type" data-slug="commentaries-reviews"> Commentaries & Reviews </span> <span class="journal"> Journal of Cell Biology </span> </div> <a href="https://rupress.org/jcb/article/217/1/79/54862/Stem-cells-Aging-and-transcriptional" target="_self" class="t-list-label"> Stem cells: Aging and transcriptional fingerprints </a> <p class="publication_item__authors"> Brice E Keyes and Elaine Fuchs </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://aacrjournals.org/cancerres/article/77/20/5564/622757/Therapeutic-Targeting-of-the-CBP-p300-Bromodomain "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://aacrjournals.org/cancerres/article/77/20/5564/622757/Therapeutic-Targeting-of-the-CBP-p300-Bromodomain "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path 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d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://aacrjournals.org/cancerres/article/77/20/5564/622757/Therapeutic-Targeting-of-the-CBP-p300-Bromodomain "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 10.15.2017 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Cancer Research </span> </div> <a href="https://aacrjournals.org/cancerres/article/77/20/5564/622757/Therapeutic-Targeting-of-the-CBP-p300-Bromodomain" target="_self" class="t-list-label"> Therapeutic Targeting of the CBP/p300 Bromodomain Blocks the Growth of Castration-Resistant Prostate Cancer </a> <p class="publication_item__authors"> Lingyan Jin, Jesse Garcia, Emily Chan, Cecile de la Cruz, Ehud Segal, Mark Merchant, Samir Kharbanda, Ryan Raisner, Peter M Haverty, Zora Modrusan, Justin Ly, Edna Choo, Susan Kaufman, Maureen H Beresini, F Anthony Romero, Steven Magnuson and Karen E Gascoigne </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" 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<a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0185849 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" 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stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 10.03.2017 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> PLOS One </span> </div> <a href="https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0185849" target="_self" class="t-list-label"> Anticipating, measuring, and minimizing MEMS mirror scan error to improve laser scanning microscopy’s speed and accuracy </a> <p class="publication_item__authors"> John P. Giannini, Andrew G. York and Hari Shroff </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.science.org/doi/10.1126/scisignal.aam6291 "> <svg height="30" viewBox="0 0 30 30" width="30"><g 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0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.science.org/doi/10.1126/scisignal.aam6291 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.science.org/doi/10.1126/scisignal.aam6291 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 09.12.2017 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Science Signaling </span> </div> <a href="https://www.science.org/doi/10.1126/scisignal.aam6291" target="_self" class="t-list-label"> Regulation of autophagy, NF-κB signaling, and cell viability by miR-124 in KRAS mutant mesenchymal-like NSCLC cells </a> <p class="publication_item__authors"> Anita K Mehta, Kevin Hua, William Whipple, Minh-Thuy Nguyen, Ching-Ti Liu, Johannes Haybaeck, Joanne Weidhaas, Jeff Settleman and Anurag Singh </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://link.springer.com/article/10.1007%2Fs00424-017-2046-3 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" 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0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://link.springer.com/article/10.1007%2Fs00424-017-2046-3 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 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0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 08.05.2017 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Pflugers Archive; European Journal of Physiology </span> </div> <a href="https://link.springer.com/article/10.1007%2Fs00424-017-2046-3" target="_self" class="t-list-label"> The naked mole-rat exhibits an unusual cardiac myofilament protein profile providing new insights into heart function of this naturally subterranean rodent </a> <p class="publication_item__authors"> Grimes KM, Barefield DY, Kumar M, McNamara JW, Weintraub ST, de Tombe PP, Sadayappan S, Buffenstein R. </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.nature.com/articles/nm.4382 "> <svg 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0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 08.04.2017 </span> <span class="post-type" data-slug="commentaries-reviews"> Commentaries & Reviews </span> <span class="journal"> Nature Medicine. </span> </div> <a href="https://www.nature.com/articles/nm.4382" target="_self" class="t-list-label"> A three-drug combination to treat BRAF-mutant cancers </a> <p class="publication_item__authors"> Firestone AJ, Settleman J. </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://onlinelibrary.wiley.com/doi/10.1002/yea.3235 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://onlinelibrary.wiley.com/doi/10.1002/yea.3235 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 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"> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 06.08.2017 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Yeast </span> </div> <a href="https://onlinelibrary.wiley.com/doi/10.1002/yea.3235" target="_self" class="t-list-label"> An estradiol-inducible promoter enables fast, graduated control of gene expression in fission yeast </a> <p class="publication_item__authors"> Makoto J. Ohira, David G. Hendrickson, R. Scott McIsaac and Nicholas Rhind </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472741/ "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472741/ "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472741/ "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 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0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 05.25.2017 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Aging </span> </div> <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472741/" target="_self" class="t-list-label"> The protein kinase MBK-1 contributes to lifespan extension in daf-2 mutant and germline-deficient Caenorhabditis elegans </a> <p class="publication_item__authors"> Mack HID, Zhang P, Fonslow BR, Yates JR. </p> </div> </article> <article class="publication_item 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1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 05.10.2017 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Breast Cancer Research and Treatment </span> </div> <a href="https://link.springer.com/article/10.1007/s10549-017-4279-4" target="_self" class="t-list-label"> Trastuzumab uptake and its relation to efficacy in an animal model of HER2-positive breast cancer brain metastasis </a> <p class="publication_item__authors"> Gail D Lewis Phillips, Merry C Nishimura, Jennifer Arca Lacap, Samir Kharbanda, Elaine Mai, Janet Tien, Kimberly Malesky, Simon P Williams, Jan Marik and Heidi S Phillips </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526670/ "> <svg height="30" viewBox="0 0 30 30" 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0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 04.18.2017 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Cell Reports </span> </div> <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526670/" target="_self" class="t-list-label"> How a Mutation that Slows Aging Can Also Disproportionately Extend End-of-Life Decrepitude </a> <p class="publication_item__authors"> Podshivalova K, Kerr RA, Kenyon C. </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div 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1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 03.23.2017 </span> <span class="post-type" data-slug="commentaries-reviews"> Commentaries & Reviews </span> <span class="journal"> Cell </span> </div> <a href="https://www.sciencedirect.com/science/article/pii/S0092867417302453?via=ihub" target="_self" class="t-list-label"> The Upsides and Downsides of Organelle Interconnectivity </a> <p class="publication_item__authors"> Gottschling DE, Nyström T. </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div 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1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 11.08.2016 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Frontiers in Neuroscience. </span> </div> <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099538/" target="_self" class="t-list-label"> Extended Postnatal Brain Development in the Longest-Lived Rodent: Prolonged Maintenance of Neotenous Traits in the Naked Mole-Rat Brain </a> <p class="publication_item__authors"> Orr ME, Garbarino VR, Salinas A, Buffenstein R. </p> </div> </article> <article class="publication_item from-bottom__0"> <div 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stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://academic.oup.com/plcell/article/28/11/2700/6098249?login=false "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://academic.oup.com/plcell/article/28/11/2700/6098249?login=false "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://academic.oup.com/plcell/article/28/11/2700/6098249?login=false "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 11.01.2016 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Plant Cell </span> </div> <a href="https://academic.oup.com/plcell/article/28/11/2700/6098249?login=false" target="_self" class="t-list-label"> Draft Assembly of Elite Inbred Line PH207 Provides Insights into Genomic and Transcriptome Diversity in Maize </a> <p class="publication_item__authors"> Candice N. Hirsch, Cory D. Hirsch, Alex B. Brohammer, Megan J. Bowman, Ilya Soifer, Omer Barad, Doron Shem-Tov, Kobi Baruch, Fei Lu, Alvaro G. Hernandez, Christopher J. Fields, Chris L. Wright, Klaus Koehler, Nathan M. Springer, Edward Buckler, C. Robin Buell, Natalia de Leon, Shawn M. Kaeppler, Kevin L. Childs and Mark A. Mikel </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.ncbi.nlm.nih.gov/pubmed/27570078 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" 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1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.ncbi.nlm.nih.gov/pubmed/27570078 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.ncbi.nlm.nih.gov/pubmed/27570078 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 08.26.2016 </span> <span class="post-type" data-slug="commentaries-reviews"> Commentaries & Reviews </span> <span class="journal"> Ageing Research Reviews </span> </div> <a href="https://www.ncbi.nlm.nih.gov/pubmed/27570078" target="_self" class="t-list-label"> Cutting back on the essentials: Can manipulating intake of specific amino acids modulate health and lifespan? </a> <p class="publication_item__authors"> Brown-Borg HM, Buffenstein R. </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper 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href="mailto:?body=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003814/ "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 08.24.2016 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Cell Systems </span> </div> <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003814/" target="_self" class="t-list-label"> Deep Proteome Analysis Identifies Age-Related Processes in C. elegans </a> <p class="publication_item__authors"> Narayan V, Ly T, Pourkarimi E, Murillo AB, Gartner A, Lamond AI, Kenyon C. </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div 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23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935753/ "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 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href="mailto:?body=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935753/ "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 06.30.2016 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Mammalian Genome </span> </div> <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935753/" target="_self" class="t-list-label"> Unraveling the message: insights into comparative genomics of the naked mole-rat </a> <p class="publication_item__authors"> Lewis KN, Soifer I, Melamud E, Roy M, McIsaac RS, Hibbs M, Buffenstein R. </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper 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23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://twitter.com/share?url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026797/ "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M20.813 11.486a3.075 3.075 0 0 0 1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 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href="mailto:?body=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026797/ "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 06.30.2016 </span> <span class="post-type" data-slug="commentaries-reviews"> Commentaries & Reviews </span> <span class="journal"> Cell Cycle </span> </div> <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026797/" target="_self" class="t-list-label"> TORquing metabolic reprogramming in cancer cells </a> <p class="publication_item__authors"> Pusapati R, Settleman J. </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> 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fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 06.14.2016 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Cell Metabolism </span> </div> <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794336/" target="_self" class="t-list-label"> Reversible Age-Related Phenotypes Induced during Larval Quiescence in C. elegans </a> <p class="publication_item__authors"> Roux AE, Langhans K, Huynh W, Kenyon C. </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g 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fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 05.21.2016 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Cell Stress Chaperones </span> </div> <a href="https://www.sciencedirect.com/science/article/pii/S1355814523004467?via%3Dihub" target="_self" class="t-list-label"> Determinants of rodent longevity in the chaperone-protein degradation network </a> <p class="publication_item__authors"> Karl A Rodriguez, Joseph M Valentine, David A Kramer, Jonathan A Gelfond, Deborah M Kristan, Eviatar Nevo and Rochelle Buffenstein </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> 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0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 05.20.2016 </span> <span class="post-type" data-slug="commentaries-reviews"> Commentaries & Reviews </span> <span class="journal"> eLIFE </span> </div> <a href="https://elifesciences.org/articles/16598" target="_self" class="t-list-label"> RNA Localization: Finding FISH in a small pond </a> <p class="publication_item__authors"> Calvin H Jan </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g 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</div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 04.12.2016 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Autophagy </span> </div> <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835961/" target="_self" class="t-list-label"> Mechanisms regulating proteostasis are involved in sympatric speciation of the blind mole rat, Spalax galili </a> <p class="publication_item__authors"> Rodriguez KA, Li K, Nevo E, Buffenstein R. </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.jove.com/t/54239/genome-wide-purification-extrachromosomal-circular-dna-from "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M15.896 23.864h-3.325v-7.842h-1.662V13.32h1.662v-1.623c0-2.204.938-3.515 3.604-3.515h2.219v2.703h-1.387c-1.038 0-1.107.377-1.107 1.082l-.004 1.353h2.513l-.294 2.702h-2.22v7.842h.001z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" 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href="https://www.linkedin.com/shareArticle?url=https://www.jove.com/t/54239/genome-wide-purification-extrachromosomal-circular-dna-from "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.jove.com/t/54239/genome-wide-purification-extrachromosomal-circular-dna-from "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 04.04.2016 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> JOVE </span> </div> <a href="https://www.jove.com/t/54239/genome-wide-purification-extrachromosomal-circular-dna-from" target="_self" class="t-list-label"> Genome-wide Purification of Extrachromosomal Circular DNA from Eukaryotic Cells </a> <p class="publication_item__authors"> Henrik D Møller, Rasmus K Bojsen, Chris Tachibana, Lance Parsons, David Botstein and Birgitte Regenberg </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" 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</div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 01.21.2016 </span> <span class="post-type" data-slug="commentaries-reviews"> Commentaries & Reviews </span> <span class="journal"> Nature </span> </div> <a href="https://www.ncbi.nlm.nih.gov/pubmed/26735017" target="_self" class="t-list-label"> Cancer: Bet on drug resistance. </a> <p class="publication_item__authors"> Settleman J. </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle 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12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.ncbi.nlm.nih.gov/pubmed/26995762 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 01.01.2016 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Annals of the New York Academy of Sciences </span> </div> <a href="https://www.ncbi.nlm.nih.gov/pubmed/26995762" target="_self" class="t-list-label"> From yeast to human: exploring the comparative biology of methionine restriction in extending eukaryotic life span. </a> <p class="publication_item__authors"> McIsaac RS, Lewis KN, Gibney PA, Buffenstein R. </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 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1.291-1.714 5.697 5.697 0 0 1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586841/ "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586841/ "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 09.22.2015 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> Proceedings of the National Academy of Sciences </span> </div> <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4586841/" target="_self" class="t-list-label"> Sympatric speciation revealed by genome-wide divergence in the blind mole rat Spalax </a> <p class="publication_item__authors"> Li K, Hong W, Jiao H, Wang GD, Rodriguez KA, Buffenstein R, Zhao Y, Nevo E, Zhao H. </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 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1-1.866.752 2.86 2.86 0 0 0-2.143-.979c-1.622 0-2.937 1.388-2.937 3.098 0 .243.024.48.075.706-2.44-.13-4.605-1.362-6.054-3.237a3.22 3.22 0 0 0-.398 1.558c0 1.074.519 2.023 1.307 2.58a2.832 2.832 0 0 1-1.331-.388v.038c0 1.502 1.012 2.754 2.357 3.038a2.734 2.734 0 0 1-.775.109c-.189 0-.374-.019-.552-.055.373 1.23 1.458 2.127 2.744 2.151a5.703 5.703 0 0 1-4.35 1.284 8.01 8.01 0 0 0 4.504 1.391c5.404 0 8.357-4.72 8.357-8.815 0-.135-.002-.268-.008-.4a6.14 6.14 0 0 0 1.466-1.605 5.63 5.63 0 0 1-1.687.488z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="https://www.linkedin.com/shareArticle?url=https://www.pnas.org/doi/full/10.1073/pnas.1508825112 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M8.526 12.554h2.658v9.263H8.526v-9.263zm1.26-1.158h-.018c-.962 0-1.586-.708-1.586-1.605 0-.915.642-1.61 1.623-1.61.98 0 1.584.693 1.603 1.607 0 .897-.622 1.608-1.621 1.608zm12.032 10.422h-3.014v-4.794c0-1.255-.471-2.11-1.508-2.11-.793 0-1.234.577-1.439 1.135-.077.199-.065.477-.065.757v5.012h-2.986s.039-8.492 0-9.264h2.986v1.454c.177-.635 1.13-1.543 2.653-1.543 1.89 0 3.373 1.334 3.373 4.202v5.151z"></path></g></svg> </a> <a class=" share_button_options-link" target="_blank" href="mailto:?body=https://www.pnas.org/doi/full/10.1073/pnas.1508825112 "> <svg height="30" viewBox="0 0 30 30" width="30"><g fill="none" fill-rule="evenodd"><circle cx="15" cy="15" r="14" stroke="#FFF" stroke-width="2"></circle><path fill="#FFF" d="M22.5 13.063v6.152c0 .34-.131.632-.393.875a1.343 1.343 0 0 1-.946.365H8.839c-.368 0-.683-.122-.946-.365a1.151 1.151 0 0 1-.393-.875v-6.152c.246.253.527.478.845.674 2.02 1.27 3.407 2.162 4.16 2.673.319.217.577.386.775.508.198.121.462.245.79.371.33.127.637.19.922.19h.017c.284 0 .591-.063.92-.19.33-.126.593-.25.791-.371.198-.122.456-.291.775-.508.948-.635 2.338-1.526 4.168-2.673.318-.201.597-.426.837-.674zm-1.34-3.518c.363 0 .677.122.942.365.265.242.398.534.398.875 0 .408-.137.798-.41 1.17a3.84 3.84 0 0 1-1.021.953 7005.44 7005.44 0 0 0-3.918 2.518l-.356.236a8.93 8.93 0 0 1-.887.546c-.17.093-.33.163-.481.21-.15.046-.29.07-.419.07h-.016c-.129 0-.268-.024-.419-.07a2.628 2.628 0 0 1-.481-.21 8.812 8.812 0 0 1-.436-.251c-.12-.075-.27-.173-.452-.295-.18-.121-.3-.2-.355-.236-.407-.264-.956-.619-1.648-1.063l-.545-.35c-.955-.613-1.527-.981-1.716-1.105a4.025 4.025 0 0 1-.98-.895c-.307-.38-.46-.732-.46-1.057 0-.403.116-.74.347-1.008.232-.268.563-.403.992-.403z"></path></g></svg> </a> </div> </div> </div> </div> </div> <div class="publication_item__content"> <div class="publication_item__meta t-label-small-medium"> <span class="date"> 06.16.2015 </span> <span class="post-type" data-slug="publications"> Publications </span> <span class="journal"> PNAS </span> </div> <a href="https://www.pnas.org/doi/full/10.1073/pnas.1508825112" target="_self" class="t-list-label"> Extrachromosomal circular DNA is common in yeast </a> <p class="publication_item__authors"> Henrik D. Møller, Lance Parsons, Tue S. Jørgensen, David Botstein and Birgitte Regenberg </p> </div> </article> <article class="publication_item from-bottom__0"> <div class="share"> <div class="share_button_wrapper light"> <div class="share_button"> <div class="share_button_container"> <button class="share_button_svg_container"> <svg class="svg share" height="48" viewBox="0 0 48 48" width="48"><g fill="none" fill-rule="evenodd" transform="translate(1 1)"><circle cx="23" cy="23" r="23" stroke=""></circle><g stroke="" stroke-linecap="round" stroke-linejoin="round" stroke-width="2" transform="translate(13 13)"><circle cx="15" cy="3" r="3"></circle><circle cx="3" cy="10" r="3"></circle><circle cx="15" cy="17" r="3"></circle><path d="M5.59 11.51l6.83 3.98M12.41 4.51L5.59 8.49"></path></g></g></svg> </button> <div class="share_button_options"> <a class="share_button_options-link" target="_blank" href="https://www.facebook.com/sharer/sharer.php?u=https://www.sciencedirect.com/science/article/abs/pii/S0959440X15000615?via%3Dihub "> 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} else if (/Edge/.test(ua)) { return "Edge"; } else if (android && /Silk\//.test(ua)) { return "Silk"; } else if (/Chrome/.test(ua)) { return "Chrome"; } else if (/Firefox/.test(ua)) { return "Firefox"; } else if (android) { return "AOSP"; } else if (/MSIE|Trident/.test(ua)) { return "IE"; } else if (/Safari\//.test(ua)) { return "Safari"; } else if (/AppleWebKit/.test(ua)) { return "WebKit"; } return ""; } function _detectBrowserVersion(ua, browser) { if (browser === "Opera") { return /Opera Mini/.test(ua) ? _getVersion(ua, "Opera Mini/") : / OPR/.test(ua) ? _getVersion(ua, " OPR/") : _getVersion(ua, " OPT/"); } else if (browser === "Chrome for iOS") { return _getVersion(ua, "CriOS/"); } else if (browser === "Edge") { return _getVersion(ua, "Edge/"); } else if (browser === "Chrome") { return _getVersion(ua, "Chrome/"); } else if (browser === "Firefox") { return _getVersion(ua, "Firefox/"); } else if (browser === "Silk") { return _getVersion(ua, "Silk/"); } else if (browser === "AOSP") { return _getVersion(ua, "Version/"); } else if (browser === "IE") { return /IEMobile/.test(ua) ? _getVersion(ua, "IEMobile/") : /MSIE/.test(ua) ? _getVersion(ua, "MSIE ") : _getVersion(ua, "rv:"); } else if (browser === "Safari") { return _getVersion(ua, "Version/"); } else if (browser === "WebKit") { return _getVersion(ua, "WebKit/"); } return "0.0.0"; } function _getVersion(ua, token) { try { return _normalizeSemverString(ua.split(token)[1].trim().split(/[^\w\.]/)[0]); } catch (o_O) { } return "0.0.0"; } function _normalizeSemverString(version) { const ary = version.split(/[\._]/); return (parseInt(ary[0], 10) || 0) + "." + (parseInt(ary[1], 10) || 0) + "." + (parseInt(ary[2], 10) || 0); } function _isWebView(ua, os, browser, version, options) { switch (os + browser) { case "iOSSafari": return false; case "iOSWebKit": return _isWebView_iOS(options); case "AndroidAOSP": return false; case "AndroidChrome": return parseFloat(version) >= 42 ? /; wv/.test(ua) : /\d{2}\.0\.0/.test(version) ? true : _isWebView_Android(options); } return false; } function _isWebView_iOS(options) { const document = (window["document"] || {}); if ("WEB_VIEW" in options) { return options["WEB_VIEW"]; } return !("fullscreenEnabled" in document || "webkitFullscreenEnabled" in document || false); } function _isWebView_Android(options) { if ("WEB_VIEW" in options) { return options["WEB_VIEW"]; } return !("requestFileSystem" in window || "webkitRequestFileSystem" in window || false); } const options = {}, nav = window.navigator || {}, ua = nav.userAgent || "", os = _detectOS(ua), browser = _detectBrowser(ua), browserVersion = _detectBrowserVersion(ua, browser); isWebView = _isWebView(ua, os, browser, browserVersion, options); } return isWebView; } function isAllowedWebViewForUserAgent(provider) { const facebookAllowedWebViews = [ 'Instagram', 'FBAV', 'FBAN' ]; let whitelist = []; if (provider && provider === 'facebook') { whitelist = facebookAllowedWebViews; } const nav = window.navigator || {}, ua = nav.userAgent || ""; if (whitelist.length && ua.match(new RegExp(whitelist.join('|')))) { return true; } return false; } function disableButtonInWebView(providerButtonElement) { if (providerButtonElement) { providerButtonElement.classList.add('nsl-disabled-provider'); providerButtonElement.setAttribute('href', '#'); providerButtonElement.addEventListener('pointerdown', (e) => { if (!window._nslWebViewNoticeElement) { window._nslWebViewNoticeElement = document.createElement('div'); window._nslWebViewNoticeElement.id = "nsl-notices-fallback"; window._nslWebViewNoticeElement.addEventListener('pointerdown', function (e) { this.parentNode.removeChild(this); window._nslWebViewNoticeElement = null; }); const webviewNoticeHTML = '<div class="error"><p>' + scriptOptions._localizedStrings.webview_notification_text + '</p></div>'; window._nslWebViewNoticeElement.insertAdjacentHTML("afterbegin", webviewNoticeHTML); document.body.appendChild(window._nslWebViewNoticeElement); } }); } } window._nslDOMReady(function () { window.nslRedirect = function (url) { if (scriptOptions._redirectOverlay) { const overlay = document.createElement('div'); overlay.id = "nsl-redirect-overlay"; let overlayHTML = ''; const overlayContainer = "<div id='nsl-redirect-overlay-container'>", overlayContainerClose = "</div>", overlaySpinner = "<div id='nsl-redirect-overlay-spinner'></div>", overlayTitle = "<p id='nsl-redirect-overlay-title'>" + scriptOptions._localizedStrings.redirect_overlay_title + "</p>", overlayText = "<p id='nsl-redirect-overlay-text'>" + scriptOptions._localizedStrings.redirect_overlay_text + "</p>"; switch (scriptOptions._redirectOverlay) { case "overlay-only": break; case "overlay-with-spinner": overlayHTML = overlayContainer + overlaySpinner + overlayContainerClose; break; default: overlayHTML = overlayContainer + overlaySpinner + overlayTitle + overlayText + overlayContainerClose; break; } overlay.insertAdjacentHTML("afterbegin", overlayHTML); document.body.appendChild(overlay); } window.location = url; }; let targetWindow = scriptOptions._targetWindow || 'prefer-popup', lastPopup = false; document.addEventListener('click', function (e) { if (e.target) { const buttonLinkElement = e.target.closest('a[data-plugin="nsl"][data-action="connect"]') || e.target.closest('a[data-plugin="nsl"][data-action="link"]'); if (buttonLinkElement) { if (lastPopup && !lastPopup.closed) { e.preventDefault(); lastPopup.focus(); } else { let href = buttonLinkElement.href, success = false; if (href.indexOf('?') !== -1) { href += '&'; } else { href += '?'; } const redirectTo = buttonLinkElement.dataset.redirect; if (redirectTo === 'current') { href += 'redirect=' + encodeURIComponent(window.location.href) + '&'; } else if (redirectTo && redirectTo !== '') { href += 'redirect=' + encodeURIComponent(redirectTo) + '&'; } if (targetWindow !== 'prefer-same-window' && checkWebView()) { targetWindow = 'prefer-same-window'; } if (targetWindow === 'prefer-popup') { lastPopup = NSLPopup(href + 'display=popup', 'nsl-social-connect', buttonLinkElement.dataset.popupwidth, buttonLinkElement.dataset.popupheight); if (lastPopup) { success = true; e.preventDefault(); } } else if (targetWindow === 'prefer-new-tab') { const newTab = window.open(href + 'display=popup', '_blank'); if (newTab) { if (window.focus) { newTab.focus(); } success = true; window._nslHasOpenedPopup = true; e.preventDefault(); } } if (!success) { window.location = href; e.preventDefault(); } } } } }); let buttonCountChanged = false; const googleLoginButtons = document.querySelectorAll(' a[data-plugin="nsl"][data-provider="google"]'); if (googleLoginButtons.length && checkWebView()) { googleLoginButtons.forEach(function (googleLoginButton) { if (scriptOptions._unsupportedWebviewBehavior === 'disable-button') { disableButtonInWebView(googleLoginButton); } else { googleLoginButton.remove(); buttonCountChanged = true; } }); } const facebookLoginButtons = document.querySelectorAll(' a[data-plugin="nsl"][data-provider="facebook"]'); if (facebookLoginButtons.length && checkWebView() && /Android/.test(window.navigator.userAgent) && !isAllowedWebViewForUserAgent('facebook')) { facebookLoginButtons.forEach(function (facebookLoginButton) { if (scriptOptions._unsupportedWebviewBehavior === 'disable-button') { disableButtonInWebView(facebookLoginButton); } else { facebookLoginButton.remove(); buttonCountChanged = true; } }); } const separators = document.querySelectorAll('div.nsl-separator'); if (buttonCountChanged && separators.length) { separators.forEach(function (separator) { const separatorParentNode = separator.parentNode; if (separatorParentNode) { const separatorButtonContainer = separatorParentNode.querySelector('div.nsl-container-buttons'); if (separatorButtonContainer && !separatorButtonContainer.hasChildNodes()) { separator.remove(); } } }) } });})();</script> </body> </html>

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