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[o]" accesskey="o" class=""><span>Најава</span></a> </li> </ul> </div> </div> </div> <div id="vector-user-links-dropdown" class="vector-dropdown vector-user-menu vector-button-flush-right vector-user-menu-logged-out" title="Повеќе можности" > <input type="checkbox" id="vector-user-links-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-user-links-dropdown" class="vector-dropdown-checkbox " aria-label="Лични алатки" > <label id="vector-user-links-dropdown-label" for="vector-user-links-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-ellipsis mw-ui-icon-wikimedia-ellipsis"></span> <span class="vector-dropdown-label-text">Лични алатки</span> </label> <div class="vector-dropdown-content"> <div id="p-personal" class="vector-menu mw-portlet mw-portlet-personal" title="Корисничко мени" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="pt-sitesupport" class="user-links-collapsible-item mw-list-item"><a href="https://donate.wikimedia.org/?wmf_source=donate&wmf_medium=sidebar&wmf_campaign=mk.wikipedia.org&uselang=mk"><span>Дарување</span></a></li><li id="pt-contribute" class="mw-list-item"><a href="/wiki/%D0%A1%D0%BF%D0%B5%D1%86%D0%B8%D1%98%D0%B0%D0%BB%D0%BD%D0%B0:Contribute"><span class="vector-icon mw-ui-icon-edit mw-ui-icon-wikimedia-edit"></span> <span>Придонесувајте</span></a></li><li id="pt-createaccount" class="user-links-collapsible-item mw-list-item"><a href="/w/index.php?title=%D0%A1%D0%BF%D0%B5%D1%86%D0%B8%D1%98%D0%B0%D0%BB%D0%BD%D0%B0:%D0%A1%D0%BE%D0%B7%D0%B4%D0%B0%D1%98%D0%9A%D0%BE%D1%80%D0%B8%D1%81%D0%BD%D0%B8%D1%87%D0%BA%D0%B0%D0%A1%D0%BC%D0%B5%D1%82%D0%BA%D0%B0&returnto=DrugBank" title="Ви препорачуваме да направите сметка и да се најавите, иако тоа не е задолжително"><span class="vector-icon mw-ui-icon-userAdd mw-ui-icon-wikimedia-userAdd"></span> <span>Направи сметка</span></a></li><li id="pt-login" class="user-links-collapsible-item mw-list-item"><a href="/w/index.php?title=%D0%A1%D0%BF%D0%B5%D1%86%D0%B8%D1%98%D0%B0%D0%BB%D0%BD%D0%B0:%D0%9D%D0%B0%D1%98%D0%B0%D0%B2%D1%83%D0%B2%D0%B0%D1%9A%D0%B5&returnto=DrugBank" title="Ви препорачуваме да се најавите, иако тоа не е задолжително. [o]" accesskey="o"><span class="vector-icon mw-ui-icon-logIn mw-ui-icon-wikimedia-logIn"></span> <span>Најава</span></a></li> </ul> </div> </div> <div id="p-user-menu-anon-editor" class="vector-menu mw-portlet mw-portlet-user-menu-anon-editor" > <div class="vector-menu-heading"> Страници за одјавени уредници <a href="/wiki/%D0%9F%D0%BE%D0%BC%D0%BE%D1%88:%D0%92%D0%BE%D0%B2%D0%B5%D0%B4" aria-label="Дознајте повеќе за уредувањето"><span>дознајте повеќе</span></a> </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="pt-anontalk" class="mw-list-item"><a href="/wiki/%D0%A1%D0%BF%D0%B5%D1%86%D0%B8%D1%98%D0%B0%D0%BB%D0%BD%D0%B0:%D0%9C%D0%BE%D1%98%D0%A0%D0%B0%D0%B7%D0%B3%D0%BE%D0%B2%D0%BE%D1%80" title="Разговор за уредувањата од оваа IP-адреса [n]" accesskey="n"><span>Разговор</span></a></li> </ul> </div> </div> </div> </div> </nav> </div> </header> </div> <div class="mw-page-container"> <div class="mw-page-container-inner"> <div 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href="#Историја_на_верзиите"> <div class="vector-toc-text"> <span class="vector-toc-numb">1</span> <span>Историја на верзиите</span> </div> </a> <ul id="toc-Историја_на_верзиите-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Опсег_и_пристап" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Опсег_и_пристап"> <div class="vector-toc-text"> <span class="vector-toc-numb">2</span> <span>Опсег и пристап</span> </div> </a> <ul id="toc-Опсег_и_пристап-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Поврзано" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Поврзано"> <div class="vector-toc-text"> <span class="vector-toc-numb">3</span> <span>Поврзано</span> </div> </a> <ul id="toc-Поврзано-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Наводи" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Наводи"> <div class="vector-toc-text"> <span class="vector-toc-numb">4</span> <span>Наводи</span> </div> </a> <ul id="toc-Наводи-sublist" class="vector-toc-list"> </ul> </li> </ul> </div> </div> </nav> </div> </div> <div class="mw-content-container"> <main id="content" class="mw-body"> <header class="mw-body-header vector-page-titlebar"> <nav aria-label="Содржина" class="vector-toc-landmark"> <div id="vector-page-titlebar-toc" class="vector-dropdown vector-page-titlebar-toc vector-button-flush-left" title="Содржина" > <input type="checkbox" id="vector-page-titlebar-toc-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-titlebar-toc" class="vector-dropdown-checkbox " aria-label="Прик./скр. содржина" > <label id="vector-page-titlebar-toc-label" for="vector-page-titlebar-toc-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-listBullet mw-ui-icon-wikimedia-listBullet"></span> <span class="vector-dropdown-label-text">Прик./скр. содржина</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-titlebar-toc-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <h1 id="firstHeading" class="firstHeading mw-first-heading"><span class="mw-page-title-main">DrugBank</span></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" > <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="Појдете на статија на друг јазик. Достапно на 36 јазици" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-36" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">36 јазици</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-ar mw-list-item"><a href="https://ar.wikipedia.org/wiki/%D8%AF%D8%B1%D8%BA_%D8%A8%D9%86%D9%83" title="درغ بنك — арапски" lang="ar" hreflang="ar" data-title="درغ بنك" data-language-autonym="العربية" data-language-local-name="арапски" class="interlanguage-link-target"><span>العربية</span></a></li><li class="interlanguage-link interwiki-bg mw-list-item"><a href="https://bg.wikipedia.org/wiki/DrugBank" title="DrugBank — бугарски" lang="bg" hreflang="bg" data-title="DrugBank" data-language-autonym="Български" data-language-local-name="бугарски" class="interlanguage-link-target"><span>Български</span></a></li><li class="interlanguage-link interwiki-bar mw-list-item"><a href="https://bar.wikipedia.org/wiki/DrugBank" title="DrugBank — баварски" lang="bar" hreflang="bar" data-title="DrugBank" data-language-autonym="Boarisch" data-language-local-name="баварски" class="interlanguage-link-target"><span>Boarisch</span></a></li><li class="interlanguage-link interwiki-ca mw-list-item"><a href="https://ca.wikipedia.org/wiki/DrugBank" title="DrugBank — каталонски" lang="ca" hreflang="ca" data-title="DrugBank" data-language-autonym="Català" data-language-local-name="каталонски" class="interlanguage-link-target"><span>Català</span></a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/DrugBank" title="DrugBank — германски" lang="de" hreflang="de" data-title="DrugBank" data-language-autonym="Deutsch" data-language-local-name="германски" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-et mw-list-item"><a href="https://et.wikipedia.org/wiki/DrugBank" title="DrugBank — естонски" lang="et" hreflang="et" data-title="DrugBank" data-language-autonym="Eesti" data-language-local-name="естонски" class="interlanguage-link-target"><span>Eesti</span></a></li><li class="interlanguage-link interwiki-el mw-list-item"><a href="https://el.wikipedia.org/wiki/DrugBank" title="DrugBank — грчки" lang="el" hreflang="el" data-title="DrugBank" data-language-autonym="Ελληνικά" data-language-local-name="грчки" class="interlanguage-link-target"><span>Ελληνικά</span></a></li><li class="interlanguage-link interwiki-en mw-list-item"><a href="https://en.wikipedia.org/wiki/DrugBank" title="DrugBank — англиски" lang="en" hreflang="en" data-title="DrugBank" data-language-autonym="English" data-language-local-name="англиски" class="interlanguage-link-target"><span>English</span></a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/DrugBank" title="DrugBank — шпански" lang="es" hreflang="es" data-title="DrugBank" data-language-autonym="Español" data-language-local-name="шпански" class="interlanguage-link-target"><span>Español</span></a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/%D8%AF%D8%B1%D8%A7%DA%AF%E2%80%8C%D8%A8%D9%86%DA%A9" title="دراگ‌بنک — персиски" lang="fa" hreflang="fa" data-title="دراگ‌بنک" data-language-autonym="فارسی" data-language-local-name="персиски" class="interlanguage-link-target"><span>فارسی</span></a></li><li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/DrugBank" title="DrugBank — француски" lang="fr" hreflang="fr" data-title="DrugBank" data-language-autonym="Français" data-language-local-name="француски" class="interlanguage-link-target"><span>Français</span></a></li><li class="interlanguage-link interwiki-gl mw-list-item"><a href="https://gl.wikipedia.org/wiki/DrugBank" title="DrugBank — галисиски" lang="gl" hreflang="gl" data-title="DrugBank" data-language-autonym="Galego" data-language-local-name="галисиски" class="interlanguage-link-target"><span>Galego</span></a></li><li class="interlanguage-link interwiki-ko mw-list-item"><a href="https://ko.wikipedia.org/wiki/%EB%93%9C%EB%9F%AC%EA%B7%B8%EB%B1%85%ED%81%AC" title="드러그뱅크 — корејски" lang="ko" hreflang="ko" data-title="드러그뱅크" data-language-autonym="한국어" data-language-local-name="корејски" class="interlanguage-link-target"><span>한국어</span></a></li><li class="interlanguage-link interwiki-id mw-list-item"><a href="https://id.wikipedia.org/wiki/DrugBank" title="DrugBank — индонезиски" lang="id" hreflang="id" data-title="DrugBank" data-language-autonym="Bahasa Indonesia" data-language-local-name="индонезиски" class="interlanguage-link-target"><span>Bahasa Indonesia</span></a></li><li class="interlanguage-link interwiki-it mw-list-item"><a href="https://it.wikipedia.org/wiki/DrugBank" title="DrugBank — италијански" lang="it" hreflang="it" data-title="DrugBank" data-language-autonym="Italiano" data-language-local-name="италијански" class="interlanguage-link-target"><span>Italiano</span></a></li><li class="interlanguage-link interwiki-kk mw-list-item"><a href="https://kk.wikipedia.org/wiki/DrugBank" title="DrugBank — казашки" lang="kk" hreflang="kk" data-title="DrugBank" data-language-autonym="Қазақша" data-language-local-name="казашки" class="interlanguage-link-target"><span>Қазақша</span></a></li><li class="interlanguage-link interwiki-la mw-list-item"><a href="https://la.wikipedia.org/wiki/DrugBank" title="DrugBank — латински" lang="la" hreflang="la" data-title="DrugBank" data-language-autonym="Latina" data-language-local-name="латински" class="interlanguage-link-target"><span>Latina</span></a></li><li class="interlanguage-link interwiki-hu mw-list-item"><a href="https://hu.wikipedia.org/wiki/DrugBank" title="DrugBank — унгарски" lang="hu" hreflang="hu" data-title="DrugBank" data-language-autonym="Magyar" data-language-local-name="унгарски" class="interlanguage-link-target"><span>Magyar</span></a></li><li class="interlanguage-link interwiki-ml mw-list-item"><a href="https://ml.wikipedia.org/wiki/%E0%B4%A1%E0%B5%8D%E0%B4%B0%E0%B4%97%E0%B5%8D%E2%80%8C%E0%B4%AC%E0%B4%BE%E0%B4%99%E0%B5%8D%E0%B4%95%E0%B5%8D" title="ഡ്രഗ്‌ബാങ്ക് — малајалски" lang="ml" hreflang="ml" data-title="ഡ്രഗ്‌ബാങ്ക്" data-language-autonym="മലയാളം" data-language-local-name="малајалски" class="interlanguage-link-target"><span>മലയാളം</span></a></li><li class="interlanguage-link interwiki-ms mw-list-item"><a href="https://ms.wikipedia.org/wiki/DrugBank" title="DrugBank — малајски" lang="ms" hreflang="ms" data-title="DrugBank" data-language-autonym="Bahasa Melayu" data-language-local-name="малајски" class="interlanguage-link-target"><span>Bahasa Melayu</span></a></li><li class="interlanguage-link interwiki-nl mw-list-item"><a href="https://nl.wikipedia.org/wiki/DrugBank" title="DrugBank — холандски" lang="nl" hreflang="nl" data-title="DrugBank" data-language-autonym="Nederlands" data-language-local-name="холандски" class="interlanguage-link-target"><span>Nederlands</span></a></li><li class="interlanguage-link interwiki-ja mw-list-item"><a href="https://ja.wikipedia.org/wiki/DrugBank" title="DrugBank — јапонски" lang="ja" hreflang="ja" data-title="DrugBank" data-language-autonym="日本語" data-language-local-name="јапонски" class="interlanguage-link-target"><span>日本語</span></a></li><li class="interlanguage-link interwiki-frr mw-list-item"><a href="https://frr.wikipedia.org/wiki/DrugBank" title="DrugBank — севернофризиски" lang="frr" hreflang="frr" data-title="DrugBank" data-language-autonym="Nordfriisk" data-language-local-name="севернофризиски" class="interlanguage-link-target"><span>Nordfriisk</span></a></li><li class="interlanguage-link interwiki-no mw-list-item"><a href="https://no.wikipedia.org/wiki/DrugBank" title="DrugBank — норвешки букмол" lang="nb" hreflang="nb" data-title="DrugBank" data-language-autonym="Norsk bokmål" data-language-local-name="норвешки букмол" class="interlanguage-link-target"><span>Norsk bokmål</span></a></li><li class="interlanguage-link interwiki-pl mw-list-item"><a href="https://pl.wikipedia.org/wiki/DrugBank" title="DrugBank — полски" lang="pl" hreflang="pl" data-title="DrugBank" data-language-autonym="Polski" data-language-local-name="полски" class="interlanguage-link-target"><span>Polski</span></a></li><li class="interlanguage-link interwiki-pt mw-list-item"><a href="https://pt.wikipedia.org/wiki/DrugBank" title="DrugBank — португалски" lang="pt" hreflang="pt" data-title="DrugBank" data-language-autonym="Português" data-language-local-name="португалски" class="interlanguage-link-target"><span>Português</span></a></li><li class="interlanguage-link interwiki-ro mw-list-item"><a href="https://ro.wikipedia.org/wiki/DrugBank" title="DrugBank — романски" lang="ro" hreflang="ro" data-title="DrugBank" data-language-autonym="Română" data-language-local-name="романски" class="interlanguage-link-target"><span>Română</span></a></li><li class="interlanguage-link interwiki-ru mw-list-item"><a href="https://ru.wikipedia.org/wiki/DrugBank" title="DrugBank — руски" lang="ru" hreflang="ru" data-title="DrugBank" data-language-autonym="Русский" data-language-local-name="руски" class="interlanguage-link-target"><span>Русский</span></a></li><li class="interlanguage-link interwiki-sr mw-list-item"><a href="https://sr.wikipedia.org/wiki/DrugBank" title="DrugBank — српски" lang="sr" hreflang="sr" data-title="DrugBank" data-language-autonym="Српски / srpski" data-language-local-name="српски" class="interlanguage-link-target"><span>Српски / srpski</span></a></li><li class="interlanguage-link interwiki-sh mw-list-item"><a href="https://sh.wikipedia.org/wiki/DrugBank" title="DrugBank — српскохрватски" lang="sh" hreflang="sh" data-title="DrugBank" data-language-autonym="Srpskohrvatski / српскохрватски" data-language-local-name="српскохрватски" class="interlanguage-link-target"><span>Srpskohrvatski / српскохрватски</span></a></li><li class="interlanguage-link interwiki-fi mw-list-item"><a href="https://fi.wikipedia.org/wiki/DrugBank" title="DrugBank — фински" lang="fi" hreflang="fi" data-title="DrugBank" data-language-autonym="Suomi" data-language-local-name="фински" class="interlanguage-link-target"><span>Suomi</span></a></li><li class="interlanguage-link interwiki-th mw-list-item"><a href="https://th.wikipedia.org/wiki/%E0%B8%94%E0%B8%A3%E0%B8%B1%E0%B8%81%E0%B9%81%E0%B8%9A%E0%B8%87%E0%B8%81%E0%B9%8C" title="ดรักแบงก์ — тајландски" lang="th" hreflang="th" data-title="ดรักแบงก์" data-language-autonym="ไทย" data-language-local-name="тајландски" class="interlanguage-link-target"><span>ไทย</span></a></li><li class="interlanguage-link interwiki-tr mw-list-item"><a href="https://tr.wikipedia.org/wiki/DrugBank" title="DrugBank — турски" lang="tr" hreflang="tr" data-title="DrugBank" data-language-autonym="Türkçe" data-language-local-name="турски" class="interlanguage-link-target"><span>Türkçe</span></a></li><li class="interlanguage-link interwiki-uk mw-list-item"><a href="https://uk.wikipedia.org/wiki/DrugBank" title="DrugBank — украински" lang="uk" hreflang="uk" data-title="DrugBank" data-language-autonym="Українська" data-language-local-name="украински" class="interlanguage-link-target"><span>Українська</span></a></li><li class="interlanguage-link interwiki-vi mw-list-item"><a href="https://vi.wikipedia.org/wiki/DrugBank" title="DrugBank — виетнамски" lang="vi" hreflang="vi" data-title="DrugBank" data-language-autonym="Tiếng Việt" data-language-local-name="виетнамски" class="interlanguage-link-target"><span>Tiếng Việt</span></a></li><li class="interlanguage-link interwiki-zh mw-list-item"><a href="https://zh.wikipedia.org/wiki/DrugBank" title="DrugBank — кинески" lang="zh" hreflang="zh" data-title="DrugBank" data-language-autonym="中文" data-language-local-name="кинески" class="interlanguage-link-target"><span>中文</span></a></li> </ul> <div class="after-portlet after-portlet-lang"><span class="wb-langlinks-edit wb-langlinks-link"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q1122544#sitelinks-wikipedia" title="Уредување на меѓујазични врски" class="wbc-editpage">Уреди врски</a></span></div> </div> </div> </div> </header> <div class="vector-page-toolbar"> <div class="vector-page-toolbar-container"> <div id="left-navigation"> <nav aria-label="Именски простори"> <div id="p-associated-pages" class="vector-menu vector-menu-tabs mw-portlet mw-portlet-associated-pages" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-nstab-main" class="selected vector-tab-noicon mw-list-item"><a href="/wiki/DrugBank" title="Преглед на содржинската страница [c]" accesskey="c"><span>Страница</span></a></li><li id="ca-talk" class="vector-tab-noicon mw-list-item"><a href="/wiki/%D0%A0%D0%B0%D0%B7%D0%B3%D0%BE%D0%B2%D0%BE%D1%80:DrugBank" rel="discussion" title="Разговор за содржинската страница [t]" accesskey="t"><span>Разговор</span></a></li> </ul> </div> </div> <div id="vector-variants-dropdown" class="vector-dropdown emptyPortlet" > <input type="checkbox" id="vector-variants-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-variants-dropdown" class="vector-dropdown-checkbox " aria-label="Менување на јазичната варијанта" > <label id="vector-variants-dropdown-label" for="vector-variants-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet" aria-hidden="true" ><span class="vector-dropdown-label-text">македонски</span> </label> <div class="vector-dropdown-content"> <div id="p-variants" class="vector-menu mw-portlet mw-portlet-variants emptyPortlet" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> </ul> </div> </div> </div> </div> </nav> </div> <div id="right-navigation" class="vector-collapsible"> <nav aria-label="Посети"> <div id="p-views" class="vector-menu vector-menu-tabs mw-portlet mw-portlet-views" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-view" class="selected vector-tab-noicon mw-list-item"><a href="/wiki/DrugBank"><span>Читај</span></a></li><li id="ca-ve-edit" class="vector-tab-noicon mw-list-item"><a href="/w/index.php?title=DrugBank&veaction=edit" title="Уредете ја страницава [v]" accesskey="v"><span>Уреди</span></a></li><li id="ca-edit" class="collapsible vector-tab-noicon mw-list-item"><a href="/w/index.php?title=DrugBank&action=edit" title="Уредување на изворниот код на страницава [e]" accesskey="e"><span>Уреди извор</span></a></li><li id="ca-history" class="vector-tab-noicon mw-list-item"><a href="/w/index.php?title=DrugBank&action=history" title="Претходни верзии на оваа страница. [h]" accesskey="h"><span>Историја</span></a></li> </ul> </div> </div> </nav> <nav class="vector-page-tools-landmark" aria-label="Алатки за страници"> <div id="vector-page-tools-dropdown" class="vector-dropdown vector-page-tools-dropdown" > <input type="checkbox" id="vector-page-tools-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-tools-dropdown" class="vector-dropdown-checkbox " aria-label="алатник" > <label id="vector-page-tools-dropdown-label" for="vector-page-tools-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet" aria-hidden="true" ><span class="vector-dropdown-label-text">алатник</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-tools-unpinned-container" class="vector-unpinned-container"> <div id="vector-page-tools" class="vector-page-tools vector-pinnable-element"> <div class="vector-pinnable-header vector-page-tools-pinnable-header vector-pinnable-header-unpinned" data-feature-name="page-tools-pinned" data-pinnable-element-id="vector-page-tools" data-pinned-container-id="vector-page-tools-pinned-container" data-unpinned-container-id="vector-page-tools-unpinned-container" > <div class="vector-pinnable-header-label">Алатки</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-page-tools.pin">премести во страничникот</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-page-tools.unpin">скриј</button> </div> <div id="p-cactions" class="vector-menu mw-portlet mw-portlet-cactions emptyPortlet vector-has-collapsible-items" title="Повеќе можности" > <div class="vector-menu-heading"> Дејства </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-more-view" class="selected vector-more-collapsible-item mw-list-item"><a href="/wiki/DrugBank"><span>Читај</span></a></li><li id="ca-more-ve-edit" class="vector-more-collapsible-item mw-list-item"><a href="/w/index.php?title=DrugBank&veaction=edit" title="Уредете ја страницава [v]" accesskey="v"><span>Уреди</span></a></li><li id="ca-more-edit" class="collapsible vector-more-collapsible-item mw-list-item"><a href="/w/index.php?title=DrugBank&action=edit" title="Уредување на изворниот код на страницава [e]" accesskey="e"><span>Уреди извор</span></a></li><li id="ca-more-history" class="vector-more-collapsible-item mw-list-item"><a href="/w/index.php?title=DrugBank&action=history"><span>Историја</span></a></li> </ul> </div> </div> <div id="p-tb" class="vector-menu mw-portlet mw-portlet-tb" > <div class="vector-menu-heading"> Општо </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="t-whatlinkshere" class="mw-list-item"><a href="/wiki/%D0%A1%D0%BF%D0%B5%D1%86%D0%B8%D1%98%D0%B0%D0%BB%D0%BD%D0%B0:%D0%A8%D1%82%D0%BE%D0%92%D0%BE%D0%B4%D0%B8%D0%9E%D0%B2%D0%B4%D0%B5/DrugBank" title="Список на сите викистраници што водат овде [j]" accesskey="j"><span>Што води овде</span></a></li><li id="t-recentchangeslinked" class="mw-list-item"><a href="/wiki/%D0%A1%D0%BF%D0%B5%D1%86%D0%B8%D1%98%D0%B0%D0%BB%D0%BD%D0%B0:%D0%9F%D0%BE%D0%B2%D1%80%D0%B7%D0%B0%D0%BD%D0%B8%D0%9F%D1%80%D0%BE%D0%BC%D0%B5%D0%BD%D0%B8/DrugBank" rel="nofollow" title="Скорешни промени на страници со врски на оваа страница [k]" accesskey="k"><span>Поврзани промени</span></a></li><li id="t-permalink" class="mw-list-item"><a href="/w/index.php?title=DrugBank&oldid=4931298" title="Постојана врска до оваа преработка на страницата"><span>Постојана врска</span></a></li><li id="t-info" class="mw-list-item"><a href="/w/index.php?title=DrugBank&action=info" title="Повеќе информации за страницата"><span>Информации за страницата</span></a></li><li id="t-cite" class="mw-list-item"><a href="/w/index.php?title=%D0%A1%D0%BF%D0%B5%D1%86%D0%B8%D1%98%D0%B0%D0%BB%D0%BD%D0%B0:%D0%9D%D0%B0%D0%B2%D0%BE%D0%B4&page=DrugBank&id=4931298&wpFormIdentifier=titleform" title="Информации како да ја наведете оваа страница"><span>Наведи ја страницава</span></a></li><li id="t-urlshortener" class="mw-list-item"><a href="/w/index.php?title=%D0%A1%D0%BF%D0%B5%D1%86%D0%B8%D1%98%D0%B0%D0%BB%D0%BD%D0%B0:%D0%A1%D0%BA%D1%80%D0%B0%D1%82%D1%83%D0%B2%D0%B0%D1%87%D0%9D%D0%B0URL&url=https%3A%2F%2Fmk.wikipedia.org%2Fwiki%2FDrugBank"><span>Дај скратена URL</span></a></li><li id="t-urlshortener-qrcode" class="mw-list-item"><a href="/w/index.php?title=%D0%A1%D0%BF%D0%B5%D1%86%D0%B8%D1%98%D0%B0%D0%BB%D0%BD%D0%B0:QrCode&url=https%3A%2F%2Fmk.wikipedia.org%2Fwiki%2FDrugBank"><span>Преземи QR-код</span></a></li> </ul> </div> </div> <div id="p-coll-print_export" class="vector-menu mw-portlet mw-portlet-coll-print_export" > <div class="vector-menu-heading"> Печати/извези </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="coll-create_a_book" class="mw-list-item"><a href="/w/index.php?title=%D0%A1%D0%BF%D0%B5%D1%86%D0%B8%D1%98%D0%B0%D0%BB%D0%BD%D0%B0:%D0%9A%D0%BD%D0%B8%D0%B3%D0%B0&bookcmd=book_creator&referer=DrugBank"><span>Создај книга</span></a></li><li id="coll-download-as-rl" class="mw-list-item"><a href="/w/index.php?title=%D0%A1%D0%BF%D0%B5%D1%86%D0%B8%D1%98%D0%B0%D0%BB%D0%BD%D0%B0:DownloadAsPdf&page=DrugBank&action=show-download-screen"><span>Преземи како PDF</span></a></li><li id="t-print" class="mw-list-item"><a href="/w/index.php?title=DrugBank&printable=yes" title="Верзија за печатење на оваа страница [p]" accesskey="p"><span>Верзија за печатење</span></a></li> </ul> </div> </div> <div id="p-wikibase-otherprojects" class="vector-menu mw-portlet mw-portlet-wikibase-otherprojects" > <div class="vector-menu-heading"> На други проекти </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li 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class="mw-content-ltr mw-parser-output" lang="mk" dir="ltr"><table class="infobox vevent" style="width:22em;width:"><caption class="summary">DrugBank</caption><tbody><tr><td colspan="2" style="text-align:center"><span class="mw-default-size" typeof="mw:File/Frameless"><a href="/wiki/%D0%9F%D0%BE%D0%B4%D0%B0%D1%82%D0%BE%D1%82%D0%B5%D0%BA%D0%B0:Drugbank_logo.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/f/fd/Drugbank_logo.svg/220px-Drugbank_logo.svg.png" decoding="async" width="220" height="25" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/f/fd/Drugbank_logo.svg/330px-Drugbank_logo.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/f/fd/Drugbank_logo.svg/440px-Drugbank_logo.svg.png 2x" data-file-width="480" data-file-height="54" /></a></span></td></tr><tr><th colspan="2" style="text-align:center;background-color: lavender">Содржина</th></tr><tr><th scope="row" style="white-space: nowrap">Опис</th><td>база на податоци (лекови/дрога)</td></tr><tr><th scope="row" style="white-space: nowrap">Заведени видови податоци</th><td>Хемиски структури, лекови за мали молекули, биотехнолошки лекови, цели на лекови, транспортери на лекови, низа на наркотични лекови, СНП на лекови, метаболити на лекови, описи на лекови, здруженија на болести, дозирни податоци, интеракции со храна и лекови, несакани реакции на лекови, фармакологија, механизми на дејствување , метаболизам на лекови, хемиска синтеза, податоци за патенти и цени, хемиски својства, номенклатура, синоними, хемиска таксономија, спектар на лекови NMR, спектар на лекови GC-MS, спектар на лекови LC-MS</td></tr><tr><th colspan="2" style="text-align:center;background-color: lavender">Контакт</th></tr><tr><th scope="row" style="white-space: nowrap"><a href="/w/index.php?title=%D0%9D%D0%B0%D1%83%D1%87%D0%BD%D0%BE-%D0%B8%D1%81%D1%82%D1%80%D0%B0%D0%B6%D1%83%D0%B2%D0%B0%D1%87%D0%BA%D0%B8_%D0%B8%D0%BD%D1%81%D1%82%D0%B8%D1%82%D1%83%D1%82&action=edit&redlink=1" class="new" title="Научно-истражувачки институт (страницата не постои)">Истраж. центар</a></th><td>Универзитетот Алберта</td></tr><tr><th scope="row" style="white-space: nowrap"><a href="/wiki/%D0%9B%D0%B0%D0%B1%D0%BE%D1%80%D0%B0%D1%82%D0%BE%D1%80%D0%B8%D1%98%D0%B0" title="Лабораторија">Лабораторија</a></th><td>Доктор Давид Висхарт</td></tr><tr><th colspan="2" style="text-align:center;background-color: lavender">Пристап</th></tr><tr><th scope="row" style="white-space: nowrap"><a href="/wiki/%D0%9C%D1%80%D0%B5%D0%B6%D0%BD%D0%BE_%D0%BC%D0%B5%D1%81%D1%82%D0%BE" title="Мрежно место">Мреж. место</a></th><td><span class="url"><a rel="nofollow" class="external text" href="http://www.drugbank.ca">drugbank.ca</a></span></td></tr><tr><th scope="row" style="white-space: nowrap">URL за преземање</th><td><span class="url"><a rel="nofollow" class="external text" href="http://www.drugbank.ca/downloads">drugbank.ca/downloads</a></span></td></tr><tr><th colspan="2" style="text-align:center;background-color: lavender">Алатки</th></tr><tr><th colspan="2" style="text-align:center;background-color: lavender">Разно</th></tr></tbody></table> <p><b>DrugBank</b> е сеопфатна, слободно достапна, интернет база на податоци што содржи информации за <a href="/wiki/%D0%94%D1%80%D0%BE%D0%B3%D0%B0" title="Дрога">лекови</a> и цели на одредени <a href="/wiki/%D0%94%D1%80%D0%BE%D0%B3%D0%B0" title="Дрога">лекови</a>. Исто како биоинформатичките и <a href="/wiki/%D0%A5%D0%B5%D0%BC%D0%B8%D0%BD%D1%84%D0%BE%D1%80%D0%BC%D0%B0%D1%82%D0%B8%D0%BA%D0%B0" title="Хеминформатика">хеминформатичките</a> ресурси, DrugBank комбинира податоци за детална лекови (односно хемискa, фармаколошкa и фармацевтскa) со сеопфатна цел на лековита (т.е. низа, структура и пат на крвоток) и информации за нејзината улога. DrugBank користела содржина од <a href="/wiki/%D0%92%D0%B8%D0%BA%D0%B8%D0%BF%D0%B5%D0%B4%D0%B8%D1%98%D0%B0" title="Википедија">Википедија</a>. Википедија, исто така, честопати се поврзува со DrugBank. </p><p>Најновото издание на базата на податоци (верзија 5.0) содржи 9591 записи за лекови вклучувајќи 2037 ситно-молекуларни лекови одобрени од ФДА, 241лекови одобрени од ФДА кои се биотехнички (белковини / пептидни), 96 нутриционистички лекови и над 6000 експериментални лекови. Покрај тоа, 4270 секвенци кои не се редундантни белковини (т.е. целни / ензими / транспортерни / носителни) секвенци се поврзани со овие записи на лекови. Секој запис на DrugCard содржи повеќе од 200 полиња со податоци со половина од информациите кои се посветени на податоците за лекови / хемикалии, а другата половина посветена на податоците за целта на лекот или податоци за белковините. </p><p>Четири дополнителни бази на податоци, HMDB, T3DB, SMPDB и FooDB се исто така дел од генералниот опфат на метаболички/<a href="/wiki/%D0%A5%D0%B5%D0%BC%D0%B8%D0%BD%D1%84%D0%BE%D1%80%D0%BC%D0%B0%D1%82%D0%B8%D0%BA%D0%B0" title="Хеминформатика">хеминиформатски</a> бази на податоци. HMDB содржи еквивалентни информации за повеќе од 40 000 човечки метаболити, T3DB содржи информации за 3100 вообичаени токсини и загадувачи на животната средина, SMPDB содржи дијаграми на патеки за скоро 700 човечки метаболички патеки и патеки на болести, додека FooDB содржи еквивалентни информации за 28,000 компоненти за <a href="/wiki/%D0%9F%D1%80%D0%B5%D1%85%D1%80%D0%B0%D0%BD%D0%B1%D0%B5%D0%BD%D0%B8_%D0%B0%D0%B4%D0%B8%D1%82%D0%B8%D0%B2%D0%B8" title="Прехранбени адитиви">храна и додатоци на храна</a>. </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="Историја_на_верзиите"><span id=".D0.98.D1.81.D1.82.D0.BE.D1.80.D0.B8.D1.98.D0.B0_.D0.BD.D0.B0_.D0.B2.D0.B5.D1.80.D0.B7.D0.B8.D0.B8.D1.82.D0.B5"></span>Историја на верзиите</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=DrugBank&veaction=edit&section=1" title="Уреди го одделот „Историја на верзиите“" class="mw-editsection-visualeditor"><span>уреди</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=DrugBank&action=edit&section=1" title="Уреди изворен код на одделот: Историја на верзиите"><span>уреди извор</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Првата верзија на DrugBank беше објавена во 2006 година. Оваа рана објавена верзија содржеше релативно скромни информации за 841 ситно молекуларни лекови одобрени од ФДА и 113 биотехнолошки лекови. Исто така, вклучуваше 2133 информации за цели на лекови. Втората верзија на DrugBank беше објавена во 2009 година.<sup id="cite_ref-pmid18048412_1-0" class="reference"><a href="#cite_note-pmid18048412-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> Оваа значително била проширена и подобрена верзија на базата на податоци која опфаќала 1344 одобрени лекови за ситни молекули и 123 лекови за биотехника, како и 3037 уникатни цели на лековите. Верзијата 2.0 исто така, за првпат вклучуваше повлечени лекови и <a href="/wiki/%D0%A2%D1%80%D0%B3%D0%BE%D0%B2%D0%B8%D1%98%D0%B0_%D1%81%D0%BE_%D0%B4%D1%80%D0%BE%D0%B3%D0%B0" title="Трговија со дрога">недозволена лекови</a>, широките интеракции на храна-лекови и лекови-лекови, како и параметрите ADMET (апсорпција, дистрибуција, метаболизам, екскреција и токсичност). Верзијата 3.0 беше објавена во 2011 година.<sup id="cite_ref-pmid21059682_2-0" class="reference"><a href="#cite_note-pmid21059682-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> Оваа верзија содржи 1424 одобрени ситно молекуларни лекови и 132 биотехнолошки лекови, како и повеќе од 4000 уникатни цели за лекови. Верзијата 3.0 исто така вклучуваше податоци за транспортер на лекови, податоци за патека на лекови, цени на лековите, патенти и податоци за производство, како и податоци за повеќе од 5000 експериментални лекови. Верзијата 4.0 беше објавена во 2014 година.<sup id="cite_ref-pmid24203711_3-0" class="reference"><a href="#cite_note-pmid24203711-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup> Оваа верзија вклучуваше 1558 молекуларни лекови одобрени од ФДА, 155 лекови/лекови за биотехника и 4200 уникатни цели на одредени лекови. Верзијата 4.0 исто така опфати широки информации за метаболити на лекови(структури и реакции), таксономија на лекови, спектар на лекови, постојани врски со лекови и информации за синтеза на. Табела 1 дава поцелосно статистичко резиме на историјата и развојот на „DrugBank“. </p> <table class="wikitable"> <caption>Табела 1: споредби на опфатнина на различните верзии на DrugBank </caption> <tbody><tr> <th>Category </th> <th>1.0 </th> <th>2.0 </th> <th>3.0 </th> <th>4.0 </th></tr> <tr> <td><i>бр. на податочни полиња од DrugCard</i> </td> <td align="right"><span style="display:none">&10000000000000088000000</span>88 </td> <td align="right"><span style="display:none">&10000000000000108000000</span>108 </td> <td align="right"><span style="display:none">&10000000000000148000000</span>148 </td> <td align="right"><span style="display:none">&10000000000000208000000</span>208 </td></tr> <tr> <td><i>бр. на видови пребарувања</i> </td> <td align="right"><span style="display:none">&10000000000000008000000</span>8 </td> <td align="right"><span style="display:none">&10000000000000012000000</span>12 </td> <td align="right"><span style="display:none">&10000000000000016000000</span>16 </td> <td align="right"><span style="display:none">&10000000000000018000000</span>18 </td></tr> <tr> <td><i>бр. на илустирани илоги на лекови </i> </td> <td align="right"><span style="display:none">&10000000000000000000000</span>0 </td> <td align="right"><span style="display:none">&10000000000000000000000</span>0 </td> <td align="right"><span style="display:none">&10000000000000168000000</span>168 </td> <td align="right"><span style="display:none">&10000000000000232000000</span>232 </td></tr> <tr> <td><i>бр. на лекови со метаболизирачки ензимски податоц</i> </td> <td align="right"><span style="display:none">&10000000000000000000000</span>0 </td> <td align="right"><span style="display:none">&10000000000000000000000</span>0 </td> <td align="right"><span style="display:none">&10000000000000762000000</span>762 </td> <td align="right"><span style="display:none">&10000000000001037000000</span>1.037 </td></tr> <tr> <td><i>бр. на метаболити на лекови со структури</i> </td> <td align="right"><span style="display:none">&10000000000000000000000</span>0 </td> <td align="right"><span style="display:none">&10000000000000000000000</span>0 </td> <td align="right"><span style="display:none">&10000000000000000000000</span>0 </td> <td align="right"><span style="display:none">&10000000000001239000000</span>1.239 </td></tr> <tr> <td><i>бр. на реакции на метаболизам на лекови</i> </td> <td align="right"><span style="display:none">&10000000000000000000000</span>0 </td> <td align="right"><span style="display:none">&10000000000000000000000</span>0 </td> <td align="right"><span style="display:none">&10000000000000000000000</span>0 </td> <td align="right"><span style="display:none">&10000000000001308000000</span>1.308 </td></tr> <tr> <td><i>бр.на илустрирани патеки на метаболизам на лекови</i> </td> <td align="right"><span style="display:none">&10000000000000000000000</span>0 </td> <td align="right"><span style="display:none">&10000000000000000000000</span>0 </td> <td align="right"><span style="display:none">&10000000000000000000000</span>0 </td> <td align="right"><span style="display:none">&10000000000000053000000</span>53 </td></tr> <tr> <td><i>бр. на лекови со податоци за транспортер на лекови</i> </td> <td align="right"><span style="display:none">&10000000000000000000000</span>0 </td> <td align="right"><span style="display:none">&10000000000000000000000</span>0 </td> <td align="right"><span style="display:none">&10000000000000516000000</span>516 </td> <td align="right"><span style="display:none">&10000000000000623000000</span>623 </td></tr> <tr> <td><i>бр. на лекови со информации за класификација на таксономијата</i> </td> <td align="right"><span style="display:none">&10000000000000000000000</span>0 </td> <td align="right"><span style="display:none">&10000000000000000000000</span>0 </td> <td align="right"><span style="display:none">&10000000000000000000000</span>0 </td> <td align="right"><span style="display:none">&10000000000006713000000</span>6.713 </td></tr> <tr> <td><i>бр. на ефекти на лекови поврзани со СНП</i> </td> <td align="right"><span style="display:none">&10000000000000000000000</span>0 </td> <td align="right"><span style="display:none">&10000000000000000000000</span>0 </td> <td align="right"><span style="display:none">&10000000000000113000000</span>113 </td> <td align="right"><span style="display:none">&10000000000000201000000</span>201 </td></tr> <tr> <td><i>бр. на лекови со податоци за патенти / цени / производител</i> </td> <td align="right"><span style="display:none">&10000000000000000000000</span>0 </td> <td align="right"><span style="display:none">&10000000000000000000000</span>0 </td> <td align="right"><span style="display:none">&10000000000001208000000</span>1.208 </td> <td align="right"><span style="display:none">&10000000000001450000000</span>1.450 </td></tr> <tr> <td><i>бр. на храна-лекови интеракции</i> </td> <td align="right"><span style="display:none">&10000000000000000000000</span>0 </td> <td align="right"><span style="display:none">&10000000000000714000000</span>714 </td> <td align="right"><span style="display:none">&10000000000001039000000</span>1.039 </td> <td align="right"><span style="display:none">&10000000000001180000000</span>1.180 </td></tr> <tr> <td><i>бр. на лекови-лекови интеракции</i> </td> <td align="right"><span style="display:none">&10000000000000000000000</span>0 </td> <td align="right"><span style="display:none">&10000000000000013242000</span>13,242 </td> <td align="right"><span style="display:none">&10000000000000013794999</span>13,795 </td> <td align="right"><span style="display:none">&10000000000000014150000</span>14,150 </td></tr> <tr> <td><i>бр. на параметрите ADMET (Caco-2, LogS)</i> </td> <td align="right"><span style="display:none">&10000000000000000000000</span>0 </td> <td align="right"><span style="display:none">&10000000000000276000000</span>276 </td> <td align="right"><span style="display:none">&10000000000000890000000</span>890 </td> <td align="right"><span style="display:none">&10000000000006667000000</span>6.667 </td></tr> <tr> <td><i>бр. на QSAR параметри од лекови</i> </td> <td align="right"><span style="display:none">&10000000000000005000000</span>5 </td> <td align="right"><span style="display:none">&10000000000000006000000</span>6 </td> <td align="right"><span style="display:none">&10000000000000014000000</span>14 </td> <td align="right"><span style="display:none">&10000000000000023000000</span>23 </td></tr> <tr> <td><i>бр. на лекови со постојани податоци за врзување на лекови</i> </td> <td align="right"><span style="display:none">&10000000000000000000000</span>0 </td> <td align="right"><span style="display:none">&10000000000000000000000</span>0 </td> <td align="right"><span style="display:none">&10000000000000000000000</span>0 </td> <td align="right"><span style="display:none">&10000000000000791000000</span>791 </td></tr> <tr> <td><i>бр. на лекови со спектар на NMR</i> </td> <td align="right"><span style="display:none">&10000000000000000000000</span>0 </td> <td align="right"><span style="display:none">&10000000000000000000000</span>0 </td> <td align="right"><span style="display:none">&10000000000000000000000</span>0 </td> <td align="right"><span style="display:none">&10000000000000306000000</span>306 </td></tr> <tr> <td><i>бр. на лекови со спектар на МС</i> </td> <td align="right"><span style="display:none">&10000000000000000000000</span>0 </td> <td align="right"><span style="display:none">&10000000000000000000000</span>0 </td> <td align="right"><span style="display:none">&10000000000000000000000</span>0 </td> <td align="right"><span style="display:none">&10000000000000384000000</span>384 </td></tr> <tr> <td><i>бр. на лекови со информации за хемиска синтеза</i> </td> <td align="right"><span style="display:none">&10000000000000000000000</span>0 </td> <td align="right"><span style="display:none">&10000000000000038000000</span>38 </td> <td align="right"><span style="display:none">&10000000000000038000000</span>38 </td> <td align="right"><span style="display:none">&10000000000001285000000</span>1.285 </td></tr> <tr> <td><i>бр. на лекови одобрени од ФДА за ситни молекули</i> </td> <td align="right"><span style="display:none">&10000000000000841000000</span>841 </td> <td align="right"><span style="display:none">&10000000000001344000000</span>1.344 </td> <td align="right"><span style="display:none">&10000000000001424000000</span>1.424 </td> <td align="right"><span style="display:none">&10000000000001558000000</span>1.558 </td></tr> <tr> <td><i>бр. на биотехнолошки лекови</i> </td> <td align="right"><span style="display:none">&10000000000000113000000</span>113 </td> <td align="right"><span style="display:none">&10000000000000123000000</span>123 </td> <td align="right"><span style="display:none">&10000000000000132000000</span>132 </td> <td align="right"><span style="display:none">&10000000000000155000000</span>155 </td></tr> <tr> <td><i>бр. на нутриционистички лекови</i> </td> <td align="right"><span style="display:none">&10000000000000061000000</span>61 </td> <td align="right"><span style="display:none">&10000000000000069000000</span>69 </td> <td align="right"><span style="display:none">&10000000000000082000000</span>82 </td> <td align="right"><span style="display:none">&10000000000000087000000</span>87 </td></tr> <tr> <td><i>бр. на повлечени лекови</i> </td> <td align="right"><span style="display:none">&10000000000000000000000</span>0 </td> <td align="right"><span style="display:none">&10000000000000057000000</span>57 </td> <td align="right"><span style="display:none">&10000000000000068000000</span>68 </td> <td align="right"><span style="display:none">&10000000000000078000000</span>78 </td></tr> <tr> <td><i>бр. на забранета лекови</i> </td> <td align="right"><span style="display:none">&10000000000000000000000</span>0 </td> <td align="right"><span style="display:none">&10000000000000188000000</span>188 </td> <td align="right"><span style="display:none">&10000000000000189000000</span>189 </td> <td align="right"><span style="display:none">&10000000000000190000000</span>190 </td></tr> <tr> <td><i>бр. на експериментални лекови</i> </td> <td align="right"><span style="display:none">&10000000000002894000000</span>2.894 </td> <td align="right"><span style="display:none">&10000000000003116000000</span>3.116 </td> <td align="right"><span style="display:none">&10000000000005210000000</span>5.210 </td> <td align="right"><span style="display:none">&10000000000006009000000</span>6.009 </td></tr> <tr> <td><i>бр. на експериментални и ФДА ситно молекуларни лекови</i> </td> <td align="right"><span style="display:none">&10000000000003796000000</span>3.796 </td> <td align="right"><span style="display:none">&10000000000004774000000</span>4.774 </td> <td align="right"><span style="display:none">&10000000000006684000000</span>6.684 </td> <td align="right"><span style="display:none">&10000000000007561000000</span>7.561 </td></tr> <tr> <td><i>бр. на експериментални ФДА лекови (сите видови)</i> </td> <td align="right"><span style="display:none">&10000000000003909000000</span>3.909 </td> <td align="right"><span style="display:none">&10000000000004897000000</span>4.897 </td> <td align="right"><span style="display:none">&10000000000006816000000</span>6.816 </td> <td align="right"><span style="display:none">&10000000000007713000000</span>7.713 </td></tr> <tr> <td><i>бр. на цел на лекови(уникатни)</i> </td> <td align="right"><span style="display:none">&10000000000002133000000</span>2.133 </td> <td align="right"><span style="display:none">&10000000000003037000000</span>3.037 </td> <td align="right"><span style="display:none">&10000000000004326000000</span>4.326 </td> <td align="right"><span style="display:none">&10000000000004115000000</span>4.115 </td></tr> <tr> <td><i>бр. на ензими / носители на одобрени лекови(уникатни)</i> </td> <td align="right"><span style="display:none">&10000000000000000000000</span>0 </td> <td align="right"><span style="display:none">&10000000000000000000000</span>0 </td> <td align="right"><span style="display:none">&10000000000000164000000</span>164 </td> <td align="right"><span style="display:none">&10000000000000245000000</span>245 </td></tr> <tr> <td><i>бр. на сите ензими / носители на лекови (уникатни)</i> </td> <td align="right"><span style="display:none">&10000000000000000000000</span>0 </td> <td align="right"><span style="display:none">&10000000000000000000000</span>0 </td> <td align="right"><span style="display:none">&10000000000000169000000</span>169 </td> <td align="right"><span style="display:none">&10000000000000253000000</span>253 </td></tr> <tr> <td><i>бр. на надворешни врски со бази на податоци</i> </td> <td align="right"><span style="display:none">&10000000000000012000000</span>12 </td> <td align="right"><span style="display:none">&10000000000000018000000</span>18 </td> <td align="right"><span style="display:none">&10000000000000031000000</span>31 </td> <td align="right"><span style="display:none">&10000000000000033000000</span>33 </td></tr></tbody></table> <div class="mw-heading mw-heading2"><h2 id="Опсег_и_пристап"><span id=".D0.9E.D0.BF.D1.81.D0.B5.D0.B3_.D0.B8_.D0.BF.D1.80.D0.B8.D1.81.D1.82.D0.B0.D0.BF"></span>Опсег и пристап</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=DrugBank&veaction=edit&section=2" title="Уреди го одделот „Опсег и пристап“" class="mw-editsection-visualeditor"><span>уреди</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=DrugBank&action=edit&section=2" title="Уреди изворен код на одделот: Опсег и пристап"><span>уреди извор</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Сите податоци во DrugBank се не-комерцијални или се добиени од не-комерцијален извор. Таа е слободно достапна и достапна за секого. Покрај тоа, скоро секоја ставка на податоци е целосно следлива и експлицитно се упатува на оригиналниот извор. Податоците за DrugBank се достапни преку јавен веб-интерфејс и преземања. </p><p>Корисниците можат да ја побараат DrugBank на неколку начини: </p> <ul><li>Поддржани се едноставни пребарувања за текст за целата текстуална компонента на базата на податоци. Со кликнување на копчето "Browse", се создава табеларна синопса за содржината на DrugBank. Овој преглед им овозможува на корисниците случајно да се движат низ базата на податоци или повторно да ги сортираат нејзините содржини.</li> <li>Со кликнување на даденото копче DrugCard се појавува целокупната содржина на податоци за соодветниот лек. Комплетно објаснување за сите полиња и извори на DrugCard е дадено.</li> <li>Копчето PharmaBrowse им овозможува на корисниците да пребаруваат преку лекови, групирани според нивната индикација. Ова е особено корисно за фармацевтите и лекарите, но исто така и за фармацевтските истражувачи кои бараат потенцијални лекови.</li> <li>Копчето ChemQuery им овозможува на корисниците да нацртаат (користејќи аплети ChemAxon ) или да напишат (како низа SMILES ) хемиско соединение и да пребаруваат DrugBank за хемикалии слични или идентични со барањето соединение (Слика 3).</li> <li>Копчето TextQuery поддржува пософистицирано пребарување на текст (делумни совпаѓања на зборови,фонт, промашувања и слично) на текстот на DrugBank.</li> <li>Копчето SeqSearch им овозможува на корисниците да вршат BLAST (белковински) пребарувања за секвенци на 18.000 секвенци содржани во DrugBank. Поддржани се и единечни и повеќекратни секвенци (т.е. целосен протеом ).</li> <li>Копчето Екстрактор на податоци отвора алатка за пребарување на релациони лесни за употреба, која им овозможува на корисниците да избираат или пребаруваат различни комбинации на вторични полиња. Екстрасорот за податоци е најсофистицираната алатка за пребарување на DrugBank.</li></ul> <p>Корисниците можат да преземат избрани компоненти на текст и податоци за низа од DrugBank и да ги следат најновите вести за DrugBank преку редовни извори на вести преку своето мрежно место, како и преку Twitter и Facebook. </p> <div class="mw-heading mw-heading2"><h2 id="Поврзано"><span id=".D0.9F.D0.BE.D0.B2.D1.80.D0.B7.D0.B0.D0.BD.D0.BE"></span>Поврзано</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=DrugBank&veaction=edit&section=3" title="Уреди го одделот „Поврзано“" class="mw-editsection-visualeditor"><span>уреди</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=DrugBank&action=edit&section=3" title="Уреди изворен код на одделот: Поврзано"><span>уреди извор</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><ul><li><a href="https://en.wikipedia.org/wiki/ChEMBL" class="extiw" title="en:ChEMBL">ChEMBL</a></li> <li><a href="https://en.wikipedia.org/wiki/Drug_metabolism" class="extiw" title="en:Drug metabolism">Drug metabolism</a></li> <li><a href="https://en.wikipedia.org/wiki/Human_Metabolome_Database" class="extiw" title="en:Human Metabolome Database">HMDB</a></li> <li><a href="https://en.wikipedia.org/wiki/KEGG" class="extiw" title="en:KEGG">KEGG</a></li> <li><a href="https://en.wikipedia.org/wiki/List_of_biological_databases" class="extiw" title="en:List of biological databases">List of biological databases</a></li> <li><a href="https://en.wikipedia.org/wiki/Pharmacology" class="extiw" title="en:Pharmacology">Pharmacology</a></li> <li><a href="https://en.wikipedia.org/wiki/SMPDB" class="extiw" title="en:SMPDB">SMPDB</a></li> <li><a href="https://en.wikipedia.org/wiki/T3DB" class="extiw" title="en:T3DB">T3DB</a></li> <li><a href="https://en.wikipedia.org/wiki/Therapeutic_Targets_Database" class="extiw" title="en:Therapeutic Targets Database">Therapeutic Targets Database</a></li></ul></li></ul> <div class="mw-heading mw-heading2"><h2 id="Наводи"><span id=".D0.9D.D0.B0.D0.B2.D0.BE.D0.B4.D0.B8"></span>Наводи</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=DrugBank&veaction=edit&section=4" title="Уреди го одделот „Наводи“" class="mw-editsection-visualeditor"><span>уреди</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=DrugBank&action=edit&section=4" title="Уреди изворен код на одделот: Наводи"><span>уреди извор</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="reflist columns references-column-width" style="-moz-column-width: 30em; -webkit-column-width: 30em; column-width: 30em; list-style-type: decimal;"> <ol class="references"> <li id="cite_note-pmid18048412-1"><span class="mw-cite-backlink"><a href="#cite_ref-pmid18048412_1-0">↑</a></span> <span class="reference-text"><cite id="CITEREFWishartKnox_CGuo_AC2008" class="citation journal">Wishart, DS; Knox C; Guo AC; и др. (Jan 2008). <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC2238889">„DrugBank: a knowledgebase for drugs, drug actions and drug targets“</a>. <i>Nucleic Acids Research</i>. <b>36</b> (Database issue): D901–906. <a href="/wiki/Doi" class="mw-redirect" title="Doi">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1093%2Fnar%2Fgkm958">10.1093/nar/gkm958</a>. <a href="/wiki/PMC" class="mw-redirect" title="PMC">PMC</a> <span class="cs1-lock-free" title="Слободен пристап"><a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC2238889">2238889</a></span>. <a href="/wiki/PMID" class="mw-redirect" title="PMID">PMID</a> <a rel="nofollow" class="external text" href="//pubmed.ncbi.nlm.nih.gov/18048412">18048412</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Nucleic+Acids+Research&rft.atitle=DrugBank%3A+a+knowledgebase+for+drugs%2C+drug+actions+and+drug+targets&rft.volume=36&rft.issue=Database+issue&rft.pages=D901-906&rft.date=2008-01&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2238889&rft_id=info%3Apmid%2F18048412&rft_id=info%3Adoi%2F10.1093%2Fnar%2Fgkm958&rft.aulast=Wishart&rft.aufirst=DS&rft.au=Knox+C&rft.au=Guo+AC&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2238889&rfr_id=info%3Asid%2Fmk.wikipedia.org%3ADrugBank" class="Z3988"></span><style data-mw-deduplicate="TemplateStyles:r5289462">.mw-parser-output cite.citation{font-style:inherit}.mw-parser-output .citation q{quotes:"\"""\"""'""'"}.mw-parser-output .id-lock-free a,.mw-parser-output .citation .cs1-lock-free a{background-image:url("//upload.wikimedia.org/wikipedia/commons/thumb/6/65/Lock-green.svg/9px-Lock-green.svg.png");background-image:linear-gradient(transparent,transparent),url("//upload.wikimedia.org/wikipedia/commons/6/65/Lock-green.svg");background-repeat:no-repeat;background-size:9px;background-position:right .1em center}.mw-parser-output .id-lock-limited a,.mw-parser-output .id-lock-registration a,.mw-parser-output .citation .cs1-lock-limited a,.mw-parser-output .citation .cs1-lock-registration a{background-image:url("//upload.wikimedia.org/wikipedia/commons/thumb/d/d6/Lock-gray-alt-2.svg/9px-Lock-gray-alt-2.svg.png");background-image:linear-gradient(transparent,transparent),url("//upload.wikimedia.org/wikipedia/commons/d/d6/Lock-gray-alt-2.svg");background-repeat:no-repeat;background-size:9px;background-position:right .1em center}.mw-parser-output .id-lock-subscription a,.mw-parser-output .citation .cs1-lock-subscription a{background-image:url("//upload.wikimedia.org/wikipedia/commons/thumb/a/aa/Lock-red-alt-2.svg/9px-Lock-red-alt-2.svg.png");background-image:linear-gradient(transparent,transparent),url("//upload.wikimedia.org/wikipedia/commons/a/aa/Lock-red-alt-2.svg");background-repeat:no-repeat;background-size:9px;background-position:right .1em center}.mw-parser-output .cs1-subscription,.mw-parser-output .cs1-registration{color:var(--color-subtle,#54595d)}.mw-parser-output .cs1-subscription span,.mw-parser-output .cs1-registration span{border-bottom:1px dotted;cursor:help}.mw-parser-output .cs1-ws-icon a{background-image:url("//upload.wikimedia.org/wikipedia/commons/thumb/4/4c/Wikisource-logo.svg/12px-Wikisource-logo.svg.png");background-image:linear-gradient(transparent,transparent),url("//upload.wikimedia.org/wikipedia/commons/4/4c/Wikisource-logo.svg");background-repeat:no-repeat;background-size:12px;background-position:right .1em center}.mw-parser-output code.cs1-code{color:inherit;background:inherit;border:inherit;padding:inherit}.mw-parser-output .cs1-hidden-error{display:none;font-size:100%}.mw-parser-output .cs1-visible-error{font-size:100%}.mw-parser-output .cs1-maint{display:none;color:#33aa33;margin-left:0.3em}.mw-parser-output .cs1-subscription,.mw-parser-output .cs1-registration,.mw-parser-output .cs1-format{font-size:95%}.mw-parser-output .cs1-kern-left,.mw-parser-output .cs1-kern-wl-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right,.mw-parser-output .cs1-kern-wl-right{padding-right:0.2em}.mw-parser-output .citation .mw-selflink{font-weight:inherit}</style></span> </li> <li id="cite_note-pmid21059682-2"><span class="mw-cite-backlink"><a href="#cite_ref-pmid21059682_2-0">↑</a></span> <span class="reference-text"><cite id="CITEREFKnoxLaw,_VJewison,_TLiu,_P2011" class="citation journal">Knox, C; Law, V; Jewison, T; Liu, P; Ly, S; Frolkis, A; Pon, A; Banco, K; Mak, C (Jan 2011). <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC3013709">„DrugBank 3.0: a comprehensive resource for 'omics' research on drugs“</a>. <i>Nucleic Acids Research</i>. <b>39</b> (Database issue): D1035–41. <a href="/wiki/Doi" class="mw-redirect" title="Doi">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1093%2Fnar%2Fgkq1126">10.1093/nar/gkq1126</a>. <a href="/wiki/PMC" class="mw-redirect" title="PMC">PMC</a> <span class="cs1-lock-free" title="Слободен пристап"><a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC3013709">3013709</a></span>. <a href="/wiki/PMID" class="mw-redirect" title="PMID">PMID</a> <a rel="nofollow" class="external text" href="//pubmed.ncbi.nlm.nih.gov/21059682">21059682</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Nucleic+Acids+Research&rft.atitle=DrugBank+3.0%3A+a+comprehensive+resource+for+%27omics%27+research+on+drugs.&rft.volume=39&rft.issue=Database+issue&rft.pages=D1035-41&rft.date=2011-01&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3013709&rft_id=info%3Apmid%2F21059682&rft_id=info%3Adoi%2F10.1093%2Fnar%2Fgkq1126&rft.aulast=Knox&rft.aufirst=C&rft.au=Law%2C+V&rft.au=Jewison%2C+T&rft.au=Liu%2C+P&rft.au=Ly%2C+S&rft.au=Frolkis%2C+A&rft.au=Pon%2C+A&rft.au=Banco%2C+K&rft.au=Mak%2C+C&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3013709&rfr_id=info%3Asid%2Fmk.wikipedia.org%3ADrugBank" class="Z3988"></span><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r5289462" /></span> </li> <li id="cite_note-pmid24203711-3"><span class="mw-cite-backlink"><a href="#cite_ref-pmid24203711_3-0">↑</a></span> <span class="reference-text"><cite id="CITEREFLawKnoxDjoumbouJewison2014" class="citation journal">Law, V; Knox, C; Djoumbou, Y; Jewison, T; Guo, AC; Liu, Y; Maciejewski, A; Arndt, D; Wilson, M (Jan 2014). <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC3965102">„DrugBank 5.0: shedding new light on drug metabolism“</a>. <i>Nucleic Acids Research</i>. <b>42</b> (Database issue): D1091-7. <a href="/wiki/Doi" class="mw-redirect" title="Doi">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1093%2Fnar%2Fgkt1068">10.1093/nar/gkt1068</a>. <a href="/wiki/PMC" class="mw-redirect" title="PMC">PMC</a> <span class="cs1-lock-free" title="Слободен пристап"><a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC3965102">3965102</a></span>. <a href="/wiki/PMID" class="mw-redirect" title="PMID">PMID</a> <a rel="nofollow" class="external text" href="//pubmed.ncbi.nlm.nih.gov/24203711">24203711</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Nucleic+Acids+Research&rft.atitle=DrugBank+5.0%3A+shedding+new+light+on+drug+metabolism&rft.volume=42&rft.issue=Database+issue&rft.pages=D1091-7&rft.date=2014-01&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3965102&rft_id=info%3Apmid%2F24203711&rft_id=info%3Adoi%2F10.1093%2Fnar%2Fgkt1068&rft.aulast=Law&rft.aufirst=V&rft.au=Knox%2C+C&rft.au=Djoumbou%2C+Y&rft.au=Jewison%2C+T&rft.au=Guo%2C+AC&rft.au=Liu%2C+Y&rft.au=Maciejewski%2C+A&rft.au=Arndt%2C+D&rft.au=Wilson%2C+M&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3965102&rfr_id=info%3Asid%2Fmk.wikipedia.org%3ADrugBank" class="Z3988"></span><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r5289462" /></span> </li> </ol></div></div><noscript><img src="https://login.wikimedia.org/wiki/Special:CentralAutoLogin/start?useformat=desktop&type=1x1&usesul3=0" alt="" width="1" height="1" style="border: none; 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