CINXE.COM

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block-system clearfix"> <article id="node-1098741" class="node node-product-category group_no_search_section_wrap clearfix" about="/products/enzymes" typeof="sioc:Item foaf:Document"> <header> <span property="dc:title" content="R&D Systems Enzymes" class="rdf-meta element-hidden"></span><span property="sioc:num_replies" content="0" datatype="xsd:integer" class="rdf-meta element-hidden"></span> </header> <div class="required-fields group-hero-image-wrapper field-group-html-element"><div class="field field-name-field-hero-image field-type-et-image-field field-label-hidden"><div class="field-items"><div class="field-item even"><div class=""> <div class="hero-image-text-content"> <div class="hero-image-text-content-inner"> </div> </div> <img loading="lazy" src="//resources.rndsystems.com/images/site/enzymes-header.jpg?v=2" class="et-image-image" title="R&D Systems Enzymes" alt="R&D Systems Enzymes" /> </div> </div></div></div></div><div class="product-category-search-wrapper col-xs-12 col-sm-8 col-md-9 col-lg-9 col-xl-9"><h2 class="group-search-title-wrapper field-group-html-element"><div class="field field-name-field-search-title field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Search Enzymes</div></div></div></h2><div class="group-search-wrapper field-group-div"><div class="field field-name-field-pre-faceted-search field-type-et-faceted-search field-label-hidden"><div class="field-items"><div class="field-item even"><div class=""> <form action="/search" class="form-inline" method="get" id="faceted_search_bar"> <div class="form-group keyword-input"> <input type="hidden" name="category" value="Proteins and Enzymes"> <input id="pc_facet" type="textfield" name="keywords" placeholder="Keywords"/> </div> <select id="pc_species" name="species"> <option value="*">All Species</option> <option value="Human">Human</option> <option value="Mouse">Mouse</option> <option value="Rat">Rat</option> <option value="Canine">Canine</option> </select> <input type="submit" name="submit" value="Search" id="pc_submit" class="btn btn-primary"/> </form> </div> </div></div></div></div></div><div id="product-category-wrapper" class="row group-product-category-wrapper field-group-div"><div class="col-xs-12 col-sm-8 col-md-9 col-lg-9 col-xl-9 group-left-wrapper field-group-div"><div class="group-intro field-group-div"> <div class="paragraphs-items paragraphs-items-field-introduction paragraphs-items-field-introduction-full paragraphs-items-full"> <div class="field field-name-field-introduction field-type-paragraphs field-label-hidden"><div class="field-items"><div class="field-item even"><div class="entity entity-paragraphs-item paragraphs-item-title-and-basic-html" about="" typeof=""> <div class="content"> <div class="group-basic-div field-group-div"><p class="group-desc field-group-html-element"><div class="field field-name-field-teaser-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><style type="text/css">.card {padding: 15px 0;} .group-hero-image-wrapper {margin:0 0 20px;} </style> <div id="which-elisa-is-right-for-me" name="which-elisa-is-right-for-me"> <div class="row"> <div class="col-md-2 col-sm-4 col-xs-6 text-center"> <div class="card"><a href="#bio"><img alt="Bioprocessing Enzymes" class="img-responsive center-block" src="//resources.rndsystems.com/images/site/bioprocessing-enzymes-250x250.jpg" /></a> <div class="group-title-wrapper"> <p><strong>Bioprocessing<br /> Enzymes</strong></p> </div> </div> </div> <div class="col-md-2 col-sm-4 col-xs-6 text-center"> <div class="card"><a href="#immuno"><img alt="Immunotherapy Enzymes" class="img-responsive center-block" src="//resources.rndsystems.com/images/site/immunotherapy-enzymes-250x250.jpg" /></a> <div class="group-title-wrapper"> <p><strong>Immunotherapy<br /> Enzymes</strong></p> </div> </div> </div> <div class="col-md-2 col-sm-4 col-xs-6 text-center"> <div class="card"><a href="#metabolic"><img alt="Metabolic Enzymes" class="img-responsive center-block" src="//resources.rndsystems.com/images/site/metabolic-enzymes-250x250.jpg" /></a> <div class="group-title-wrapper"> <p><strong>Metabolic<br /> Enzymes</strong></p> </div> </div> </div> <div class="col-md-2 col-sm-4 col-xs-6 text-center"> <div class="card"><a href="#ubiquitin"><img alt="Ubiquitin-related Enzymes" class="img-responsive center-block" src="//resources.rndsystems.com/images/site/ubiquitin-enzymes-250x250.jpg" /></a> <div class="group-title-wrapper"> <p><strong>Ubiquitin-related<br /> Enzymes</strong></p> </div> </div> </div> <div class="col-md-2 col-sm-4 col-xs-6 text-center"> <div class="card"><a href="#enzyme"><img alt="Enzyme Kits" class="img-responsive center-block" src="//resources.rndsystems.com/images/site/enzyme-kits-250x250.jpg" /></a> <div class="group-title-wrapper"> <p><strong>Enzyme<br /> Kits</strong></p> </div> </div> </div> <div class="col-md-2 col-sm-4 col-xs-6 text-center"> <div class="card"><a href="/services/protein-services"><img alt="Custom Enzymes" class="img-responsive center-block" src="//resources.rndsystems.com/images/site/custom-enzymes-250x250.jpg" /></a> <div class="group-title-wrapper"> <p><strong>Custom<br /> Enzymes</strong></p> </div> </div> </div> </div> </div> <p> </p> <h2 style="margin-top: 20px">What is an Enzyme?</h2> <p>Enzymes are catalysts and function by lowering the activation energy of a reaction resulting in an increase in reaction rate. Enzymes are present in all living organisms and are essential to maintaining life. These macromolecules, the vast majority being proteins, catalyze over 5000 different biochemical reactions in cells. For example, metabolic pathways are comprised of a series of enzymes that speed up chemical reactions by several orders of magnitude. These enzyme pathways continually accomplish very complex chemical reactions inside every living cell. The history of enzymes dates to the 18th and early 19th centuries. The concept was first used to explain digestion, conversion of starch to sugars, and fermentation of sugar to alcohol. The term “enzyme” was first coined by German physiologist <a href="https://en.wikipedia.org/wiki/Wilhelm_K%C3%BChne" target="_blank">Wilhelm Kuhne</a> in 1877. Today, in addition to life science research, enzymes are used in the agricultural, food, pharmaceutical, and cosmetic industries. In the pharmaceutical industry, enzymes are used in drug manufacturing, and many drugs are enzyme inhibitors that act by binding to an enzyme and blocking its activity by interfering with substrate binding.</p> <h2 style="margin-top: 20px">About R&D Systems Enzymes</h2> <p style="margin-bottom: 20px">R&D Systems offers over 800 active <a href="/search?keywords=enzymes">enzymes</a> that can be used in a variety of biological reactions and in many different applications. Our enzymes have been selected for high activity and QC tested to ensure lot-to-lot consistency and stability. We offer many recombinant enzymes produced in controlled systems to ensure lot-to-lot consistency. With over 30 years of experience offering enzymes to the research community, we continually strive to produce enzymes with the highest purity and performance.</p> </div></div></div></p></div> </div> </div> </div></div></div></div> </div><div class="group-basic-video field-group-div"> <div class="paragraphs-items paragraphs-items-field-basic-paragraph paragraphs-items-field-basic-paragraph-full paragraphs-items-full"> <div class="field field-name-field-basic-paragraph field-type-paragraphs field-label-hidden"><div class="field-items"><div class="field-item even"><div class="entity entity-paragraphs-item paragraphs-item-title-and-basic-html" about="" typeof=""> <div class="content"> <div class="group-basic-div field-group-div"><h2 class="group-title-wrapper field-group-html-element"><div class="field field-name-field-title field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Commonly Searched Enzymes </div></div></div></h2><p class="group-desc field-group-html-element"><div class="field field-name-field-teaser-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><div itemscope="" itemtype="http://schema.org/Table"><meta itemprop="about" content="Commonly Searched Enzymes "> <table cellpadding="3" cellspacing="1" class="table table-bordered table-stripped" style="margin-top: 30px" width="100%"> <tbody> <tr> <td class="lt_gray" nowrap="nowrap"><a href="/target/alpha-galactosidase-a-gla">Alpha-Galactosidase A/GLA</a></td> <td class="lt_gray" nowrap="nowrap"><a href="/search?keywords=cystatin&category=Proteins%20and%20Enzymes">Cystatins</a></td> <td class="lt_gray" nowrap="nowrap"><a href="/search?keywords=loxl&category=Proteins%20and%20Enzymes">Lysyl Oxidases</a></td> <td class="lt_gray" nowrap="nowrap"><a href="/target/u-plasminogen-activator-upa-urokinase?category=Proteins%20and%20Enzymes">u-Plasminogen Activator/uPA</a></td> </tr> <tr> <td><a href="/products/recombinant-human-lysosomal-alpha-glucosidase-gaa-cf_8329-gh">Alpha-Glucosidase/GAA</a></td> <td><a href="/target/enteropeptidase-enterokinase?category=Proteins%20and%20Enzymes">Enterokinase</a></td> <td><a href="/target/matriptase-st14?category=Proteins%20and%20Enzymes">Matriptase</a></td> <td><a href="/target/vap-1-aoc3?category=Proteins%20and%20Enzymes">VAP-1</a></td> </tr> <tr> <td class="lt_gray" nowrap="nowrap"><a href="/target/alpha-l-iduronidase-idua?category=Proteins%20and%20Enzymes">alpha-L-Iduronidase/IDUA</a></td> <td class="lt_gray" nowrap="nowrap"><a href="/target/fibroblast-activation-protein-alpha-fap?category=Proteins%20and%20Enzymes">FAP</a></td> <td class="lt_gray" nowrap="nowrap"><a href="/research-area/mmps--timps-and-related-molecules">Matrix Metalloproteinases MMPs</a></td> <td class="lt_gray" nowrap="nowrap"><a href="/search?keywords=vhl&category=Proteins%20and%20Enzymes">VHL</a></td> </tr> <tr> <td><a href="/target/dppiv-cd26?category=Proteins%20and%20Enzymes">CD26</a></td> <td><a href="/products/recombinant-human-glucosylceramidase-gba-protein-cf_7410-ghb">Glucosylceramidase/GBA</a></td> <td><a href="/target/psma-folh1-naaladase-i">PSMA</a></td> <td><a href="/target/20s-proteasome?category=Proteins%20and%20Enzymes">20s Proteasome</a></td> </tr> <tr> <td class="lt_gray" nowrap="nowrap"><a href="/target/cd39-entpd1?category=Proteins%20and%20Enzymes">CD39</a></td> <td class="lt_gray" nowrap="nowrap"><a href="/target/heparanase-hpse?category=Proteins%20and%20Enzymes">Heparanase</a></td> <td class="lt_gray" nowrap="nowrap"><a href="/target/tfpi?category=Proteins%20and%20Enzymes">TFPI</a></td> <td class="lt_gray" nowrap="nowrap"> </td> </tr> <tr> <td><a href="/target/5-nucleotidase-cd73?category=Proteins%20and%20Enzymes">CD73</a></td> <td><a href="/target/iduronate-2-sulfatase-ids?category=Proteins%20and%20Enzymes">Iduronate 2-Sulfatase/IDS</a></td> <td><a href="/research-area/mmps--timps-and-related-molecules">TIMPs</a></td> <td> </td> </tr> <tr> <td class="lt_gray" nowrap="nowrap"><a href="/search?keywords=crbn&category=Proteins%20and%20Enzymes">CRBN</a></td> <td class="lt_gray" nowrap="nowrap"><a href="/target/il-4i1?category=Proteins%20and%20Enzymes">IL-4I1</a></td> <td class="lt_gray" nowrap="nowrap"><a href="/target/ubiquitin-activating-enzyme-ube1?category=Proteins%20and%20Enzymes">UBE1</a></td> <td class="lt_gray" nowrap="nowrap"> </td> </tr> </tbody> </table> </div> <p style="margin-top: 10px"> <a name="bio"></a></p> </div></div></div></p></div> </div> </div> </div><div class="field-item odd"><div class="entity entity-paragraphs-item paragraphs-item-title-and-basic-html" about="" typeof=""> <div class="content"> <div class="group-basic-div field-group-div"><h2 class="group-title-wrapper field-group-html-element"><div class="field field-name-field-title field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Bioprocessing Enzymes</div></div></div></h2><p class="group-desc field-group-html-element"><div class="field field-name-field-teaser-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><div itemscope="" itemtype="http://schema.org/Table"><meta itemprop="about" content="Bioprocessing Enzymes"> <p style="margin-top: 30px">Enzymes for bioprocessing applications enable the rapid completion of a chemical process in a specific, controlled environment. Bioprocessing enzymes are essential tools for basic scientific research. In addition, they are used in the production of pharmaceuticals, foods, chemicals, and fuels.</p> <table cellpadding="3" cellspacing="1" class="table table-bordered table-stripped" style="margin-top: 30px" width="100%"> <tbody> <tr style="margin-bottom: 10px"> <td style="font-size: 20px"><a href="/research-area/proteases---other-enzymes">Proteases</a></td> <td style="font-size: 20px"><a href="/research-area/glycobiology--related-enzymes">Glycobiology</a></td> <td style="font-size: 20px">Nucleic Acid Enzymes</td> <td style="font-size: 20px"><a href="/research-area/other-enzymes">Other Enzymes</a></td> </tr> <tr> <td><a href="/search?keywords=carboxypeptidase&category=Proteins%20and%20Enzymes">Carboxypeptidases</a></td> <td><a href="/search?keywords=chondroitinase&category=Proteins%20and%20Enzymes">Chondroitinase</a></td> <td><a href="/products/recombinant-s-pyogenes-crispr-associated-protein-9-cf_9957-c9">Cas9</a></td> <td><a href="https://www.rndsystems.com/products/recombinant-e-coli-bira-his-tag-protein-cf_10464-ba">BirA Ligase</a></td> </tr> <tr class="lt_gray"> <td><a href="/target/enteropeptidase-enterokinase?category=Proteins%20and%20Enzymes">Enterokinase</a></td> <td><a href="/products/recombinant-human-lysosomal-alpha-glucosidase-gaa-cf_8329-gh">GAA</a></td> <td>Cpf21 (coming soon)</td> <td><a href="/products/recombinant-human-pgpep-1-protein-cf_6278-cy">PGPEP</a></td> </tr> <tr> <td><a href="/target/coagulation-factor-x?category=Proteins%20and%20Enzymes">Factor Xa</a></td> <td><a href="/products/recombinant-human-alpha-galactosidase-a-gla-protein-cf_6146-gh">GLA</a></td> <td><a href="/products/recombinant-s-marcescens-nuca-protein-cf_10038-na">NucA (Benzonase®)</a></td> <td><a href="/search?keywords=pyrophosphatase&category=Proteins%20and%20Enzymes">Pyrophosphatases</a></td> </tr> <tr> <td><a href="/target/furin?category=Proteins%20and%20Enzymes">Furin</a></td> <td><a href="/target/heparanase-hpse?category=Proteins%20and%20Enzymes">Heparanase</a></td> <td> </td> <td><a href="/search?keywords=Transglutaminase&category=Proteins%20and%20Enzymes">Transglutaminase</a></td> </tr> <tr> <td><a href="/target/matriptase-st14?category=Proteins%20and%20Enzymes">Matriptase</a></td> <td><a href="/products/heparinases">Heparinase</a></td> <td> </td> <td> </td> </tr> <tr> <td><a href="/products/recombinant-tev-protease-protein-cf_4469-tp">TEV Protease</a></td> <td><a href="/products/recombinant-f-meningosepticum-pngase-f-protein-cf_9109-gh">PNGase F</a></td> <td> </td> <td> </td> </tr> <tr> <td><a href="/target/thermolysin">Thermolysin</a></td> <td> </td> <td> </td> <td> </td> </tr> <tr> <td><a href="/target/coagulation-factor-ii-thrombin?category=Proteins%20and%20Enzymes">Thrombin</a></td> <td> </td> <td> </td> <td> </td> </tr> <tr> <td><a href="/search?keywords=trypsin&category=Proteins%20and%20Enzymes">Trypsins</a></td> <td> </td> <td> </td> <td> </td> </tr> </tbody> </table> </div> <p> </p> <p style="margin-bottom: 10px"><a class="btn btn-tertiary" href="/research-area/proteases---other-enzymes">More proteases</a><a name="immuno"></a></p> </div></div></div></p></div> </div> </div> </div><div class="field-item even"><div class="entity entity-paragraphs-item paragraphs-item-title-and-basic-html" about="" typeof=""> <div class="content"> <div class="group-basic-div field-group-div"><h2 class="group-title-wrapper field-group-html-element"><div class="field field-name-field-title field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Immunotherapy Enzymes</div></div></div></h2><p class="group-desc field-group-html-element"><div class="field field-name-field-teaser-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><div itemscope="" itemtype="http://schema.org/Table"><meta itemprop="about" content="Immunotherapy Enzymes"> <p style="margin-top: 30px">Recent successes with FDA approved immunotherapies have greatly increased interest in the field. Several immunotherapies are some of the most promising anticancer treatments. Recently, focus on metabolism in the tumor microenvironment has intensified due to its modulatory effect on immune recognition and role in elimination of tumor cells.</p> <table cellpadding="3" cellspacing="1" class="table table-bordered table-stripped" style="margin-top: 30px" width="100%"> <tbody> <tr> <td><a href="/products/recombinant-human-arginase-2-arg2-protein-cf_9767-ar">ARG2</a></td> <td><a href="/target/indoleamine-2-3-dioxygenase-ido?category=Proteins%20and%20Enzymes">IDO1</a></td> </tr> <tr> <td><a href="/target/cd38?category=Proteins%20and%20Enzymes">CD38</a></td> <td><a href="/products/recombinant-human-ido2-protein-cf_9967-ao">IDO2</a></td> </tr> <tr> <td><a href="/search?keywords=cd39&category=Proteins%20and%20Enzymes">CD39</a></td> <td><a href="/products/recombinant-human-kynureninase-protein-cf_4887-kh">Kynureninase (KYNU)</a></td> </tr> <tr> <td><a href="/target/5-nucleotidase-cd73?category=Proteins%20and%20Enzymes">CD73</a></td> <td><a href="/target/psma-folh1-naaladase-i">PSMA</a></td> </tr> <tr> <td><a href="/target/fibroblast-activation-protein-alpha-fap?category=Proteins%20and%20Enzymes">FAP</a></td> <td><a href="/target/tdo2?category=Proteins%20and%20Enzymes">TDO2</a></td> </tr> </tbody> </table> </div> <p> </p> <p style="margin-bottom: 10px"><a class="btn btn-tertiary" href="/research-area/proteases---other-enzymes">Browse more enzymes</a><a name="metabolic"></a></p> </div></div></div></p></div> </div> </div> </div><div class="field-item odd"><div class="entity entity-paragraphs-item paragraphs-item-title-and-basic-html" about="" typeof=""> <div class="content"> <div class="group-basic-div field-group-div"><h2 class="group-title-wrapper field-group-html-element"><div class="field field-name-field-title field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Metabolic Enzymes</div></div></div></h2><p class="group-desc field-group-html-element"><div class="field field-name-field-teaser-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><div itemscope="" itemtype="http://schema.org/Table"><meta itemprop="about" content="Metabolic Enzymes"> <p style="margin-top: 30px">Metabolic enzymes help carry out essential cellular functions necessary to maintain survival, growth, and homestatsis. These enzymes include kinases, dehydrogenases, lyases, oxygenases, reductases, phosphatases, carboxylases, and transferases and cover a wide range different enzymatic functions. Many common diseases have a metabolic component including diabetes, cancer, obesity, and hypertension.</p> <table cellpadding="3" cellspacing="1" class="table table-bordered table-stripped" style="margin-top: 30px" width="100%"> <tbody> <tr> <td style="font-size: 20px"><a href="/research-area/glucose-homeostasis">Glucose Metabolism</a></td> <td style="font-size: 20px">Amino Acid Metabolism</td> <td style="font-size: 20px">Nucleotide Metabolism</td> <td style="font-size: 20px">Adenosine Metabolism</td> <td style="font-size: 20px"><a href="/research-area/lipid-cholesterol-metabolism-enzymes">Lipid Metabolism</a></td> </tr> <tr> <td>Enolase (coming soon)</td> <td><a href="/products/recombinant-human-arginase-1-arg1-protein-cf_5868-ar">ARG1</a> and <a href="/products/recombinant-human-arginase-2-arg2-protein-cf_9767-ar">ARG2</a></td> <td><a href="/products/recombinant-human-dhfr-protein-cf_8456-dr">DHFR</a></td> <td><a href="/products/recombinant-human-adenosine-deaminase-ada-protein-cf_7048-ad">ADA</a></td> <td><a href="/target/asah2-n-acylsphingosine-amidohydrolase-2?category=Proteins%20and%20Enzymes">ASAH2</a></td> </tr> <tr> <td><a href="/products/recombinant-human-g6pd-his-tag-protein-cf_10096-dh">Glucose-6 Phosphate Dehydrogenase</a></td> <td><a href="/products/recombinant-human-asparagine-synthetase-asns-his-protein-cf_10193-as">ASNS New!</a></td> <td><a href="/products/recombinant-human-dihydroorotate-dehydrogenase-protein-cf_10062-dd">DHODH</a></td> <td><a href="/products/recombinant-human-adenosine-deaminase-2-cecr1-protein-cf_7518-ad">ADA2</a></td> <td><a href="/products/recombinant-mouse-carboxyl-ester-lipase-cel-protein-cf_5658-ce">CEL</a></td> </tr> <tr> <td><a href="/products/recombinant-human-hexokinase-1-protein-cf_8178-hk">Hexokinase 1</a></td> <td><a href="/products/recombinant-guinea-pig-asparaginase-his-tag-protein-cf_10238-as">ASPG New!</a></td> <td><a href="/products/recombinant-human-hprt-his-tag-protein-cf_10314-hp">HPRT</a></td> <td><a href="/search?keywords=cd39&category=Proteins%20and%20Enzymes">CD39</a></td> <td><a href="/target/carboxylesterase-2-ces2?category=Proteins%20and%20Enzymes">CES2</a></td> </tr> <tr> <td><a href="/products/recombinant-human-hexokinase-2-protein-cf_8179-hk">Hexokinase 2</a></td> <td><a href="/products/recombinant-human-bcat1-protein-cf_9536-ba">BCAT1</a> and <a href="/products/recombinant-human-bcat2-protein-cf_9537-ba">BCAT2</a></td> <td><a href="/products/recombinant-human-imp-dehydrogenase-1-impdh1-protein-cf_8904-dh">IMPDH1</a></td> <td><a href="/target/5-nucleotidase-cd73?category=Proteins%20and%20Enzymes">CD73</a></td> <td>COX (coming soon) </td> </tr> <tr> <td><a href="/products/recombinant-human-isocitrate-dehydrogenase-1-idh1-cf_7049-dh">IDH-1</a></td> <td><a href="/products/recombinant-human-ddah1-protein-cf_6530-da">DDAH1</a></td> <td><a href="/products/recombinant-human-imp-dehydrogenase-2-impdh2-protein-cf_8349-dh">IMPDH2</a></td> <td><a href="/products/recombinant-human-mtap-his-tag-protein-cf_10379-mt">MTAP</a></td> <td><a href="/search?keywords=ENPP&category=Proteins%20and%20Enzymes">ENPP2/6/7</a></td> </tr> <tr> <td><a href="/products/recombinant-human-lactate-dehydrogenase-a-ldha-protein-cf_9158-ha">LDH-A</a> and <a href="/products/recombinant-human-lactate-dehydrogenase-b-ldhb-protein-cf_9205-hb">LDH-B</a></td> <td><a href="/products/recombinant-human-glutaminase-his-tag-protein-cf_10115-gl">GLS</a></td> <td> </td> <td> </td> <td><a href="/products/recombinant-human-lipoprotein-lipase-lpl-protein-cf_9888-ll">LPL</a></td> </tr> <tr> <td><a href="/products/recombinant-human-pfkfb3-protein-cf_8566-bp">PFKFB3</a></td> <td><a href="/target/indoleamine-2-3-dioxygenase-ido?category=Proteins%20and%20Enzymes">IDO1</a> and <a href="/products/recombinant-human-ido2-protein-cf_9967-ao">IDO2</a></td> <td> </td> <td> </td> <td><a href="/products/recombinant-human-leukotriene-a4-hydrolase-lta4h-protein-cf_4008-zn">LTA4H</a></td> </tr> <tr> <td><a href="/products/recombinant-human-pgk-1-protein-cf_5455-pk">PGK-1</a></td> <td><a href="/products/recombinant-human-mat2a-his-tag-protein-cf_10315-ma">MAT2A</a></td> <td> </td> <td> </td> <td><a href="/products/recombinant-human-monoglyceride-lipase-protein-cf_7930-mg">MGLL</a></td> </tr> <tr> <td><a href="/products/recombinant-human-pkm2-protein-cf_7244-pk">PKM2</a></td> <td><a href="/products/recombinant-human-phgdh-his-tag-cf_10131-dh">PHGDH</a></td> <td> </td> <td> </td> <td><a href="/search?keywords=PLA2&category=Proteins%20and%20Enzymes">PLA2</a></td> </tr> <tr> <td><a href="/products/recombinant-human-pklr-protein-cf_8569-pk">PKLR</a></td> <td><a href="/products/recombinant-human-psat1-his-tag-protein-cf_10342-ps">PSAT1</a></td> <td> </td> <td> </td> <td><a href="/target/sphingosine-kinase-1-sphk1?category=Proteins%20and%20Enzymes">SPHK1</a> and <a href="/target/sphingosine-kinase-2-sphk2?category=Proteins%20and%20Enzymes">SPHK2</a></td> </tr> <tr> <td> </td> <td><a href="/target/tdo2?category=Proteins%20and%20Enzymes">TDO2</a></td> <td> </td> <td> </td> <td> </td> </tr> </tbody> </table> </div> <p> </p> <p style="margin-bottom: 30px"><a class="btn btn-tertiary" href="/research-area/proteases---other-enzymes">Browse more enzymes</a><a name="ubiquitin"></a></p> </div></div></div></p></div> </div> </div> </div><div class="field-item even"><div class="entity entity-paragraphs-item paragraphs-item-title-and-basic-html" about="" typeof=""> <div class="content"> <div class="group-basic-div field-group-div"><p class="group-desc field-group-html-element"><div class="field field-name-field-teaser-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><h2><a href="/products/boston-biochem-products-and-services">Ubiquitin-related Enzymes</a></h2> <div itemscope="" itemtype="http://schema.org/Table"><meta itemprop="about" content="Ubiquitin-related Enzymes"> <p style="margin-top: 30px">Our ubiquitin-related enzymes and other research products are manufactured by Boston Biochem, the leader in ubiquitin and ubiquitin-related products since 1997.</p> <table cellpadding="3" cellspacing="1" class="table table-bordered table-stripped" style="margin-top: 30px" width="100%"> <tbody> <tr> <td><a href="/pathways/autophagy-pathway" target="_blank">Autophagy</a></td> <td><a href="/products/e3-ligases">E3 Ligases</a></td> </tr> <tr> <td><a href="/search?keywords=usp5%20OR%20UCH-l3%20OR%20uch-l1%20OR%20Ataxin-3%20OR%20TNFAIP3%20OR%20RNF-2%20OR%20USP2%20OR%20USP7%20OR%20USP8%20OR%20Otubain-1&category=Proteins%20and%20Enzymes" target="_blank">Deconjugating Enzymes</a></td> <td><a href="/search?keywords=K-102%20OR%20K-2*%20OR%20K-3*%20OR%20K-400%20OR%20K-6*%20OR%20K-7*%20OR%20K-8*%20OR%20K-9*&brand=rnd">Kits</a></td> </tr> <tr> <td><a href="/research-area/deubiquitinating-enzymes--dubs" target="_blank">Deubiquitinating (DUBs)</a></td> <td><a href="/research-area/proteasome" target="_blank">Proteasome</a></td> </tr> <tr> <td><a href="/research-area/e1-ubiquitin-ubl-activating-enzymes" target="_blank">E1 Activating</a></td> <td><a href="/search?keywords=ubiquitin&category=Proteins%20and%20Enzymes&common_name=Ubiquitin" target="_blank">Ubiquitin</a></td> </tr> <tr> <td><a href="/research-area/e2-ubiquitin-ubl-conjugating-enzymes" target="_blank">E2 Conjugating</a></td> <td><a href="/search?keywords=sumo&category=Proteins%20and%20Enzymes" target="_blank">SUMO</a></td> </tr> </tbody> </table> </div> <p style="margin-bottom: 10px"> </p> <p><a name="enzyme"></a></p> </div></div></div></p></div> </div> </div> </div><div class="field-item odd"><div class="entity entity-paragraphs-item paragraphs-item-title-and-basic-html" about="" typeof=""> <div class="content"> <div class="group-basic-div field-group-div"><p class="group-desc field-group-html-element"><div class="field field-name-field-teaser-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even"><h4 style="margin-top: 30px"><a href="/search?keywords=ea00*&category=Activity%20Assays">Enzyme Activity Kits</a></h4> <p>Easy to use enzyme kits designed with the end user in mind, compatible with high-throughput applications.</p> <h4 style="margin-top: 20px"><a href="/search?keywords=es00*&category=Activity%20Assays" target="_blank">Protease substrates</a></h4> <p>Convenient fluorogenic peptide substrates for sensitive detection of enzyme activity.</p> <h4 style="margin-top: 20px"><a href="https://www.tocris.com/product-type/targeted-protein-degradation" target="_blank">PROTACs & Targeted Protein Degradation</a></h4> <p>Fast growing Targeted Protein Degradation research field with great therapeutic promise. Bio-Techne offers a complete suite of products for targeted protein degradation research.</p> <h4 style="margin-top: 20px"><a href="https://www.tocris.com/" target="_blank">Tocris Small Molecules</a><a name="custom"></a></h4> <p>Tocris Bioscience is the leading supplier of small molecules to the life science research community.</p> <h4 style="margin-top: 20px"><a href="/services/protein-services">Custom Protein/Enzyme Request</a></h4> <p>Utilize our expertise in protein expression, cell culture, protein purification, conjugation, and formulation to create an optimized protein of your choice. Make your <a href="/services/protein-services">custom protein request</a>.</p> <h4 style="margin-top: 20px"><a href="/services/bulk-quote-request">Bulk Protein Request</a></h4> <p>In the market for large quantities? Buy in bulk and save. We have the capacity and expertise to scale up protein production to meet your needs. Request your <a href="/services/bulk-quote-request">bulk protein</a> today.</p> <h2 style="margin-top: 30px">Other Resources</h2> <p><a href="/research-area/lysosomal-enzymes">Lysosomal Enzymes</a></p> <p><a href="/research-area/dna-modifying-enzymes">DNA Modifying Enzymes</a></p> <p><a href="/products/dna-damage-repair-enzymes">DNA Damage and Repair Enzymes</a></p> <p><a href="/research-area/proteases">Proteases</a></p> <p><a href="/research-area/oxidative-stress--related-enzymes">Oxidative Stress Enzymes</a></p> <p><a href="/research-area/deubiquitinating-enzymes--dubs">Deubiquitinating Enzymes - DUBs</a></p> <p><a href="/research-area/e3-ubiquitin-ligases">E3 Ligases</a></p> <p><a href="/research-area/lipid-metabolism-enzymes">Lipid Metabolism Enzymes</a></p> <p> </p> <p>Benzonase® is a registered trademark of Merck KGaA Corp.</p> <p style="margin-bottom: 10px"> </p> </div></div></div></p></div> </div> </div> </div></div></div></div> </div></div><div class="col-xs-12 col-sm-4 col-md-3 col-lg-3 col-xl-3 group-featured-content-wrapper field-group-div"><h2 class="field-group-html-element"><div class="field field-name-field-featured-content-title field-type-text field-label-hidden"><div class="field-items"><div class="field-item even"> Featured Content</div></div></div></h2> <div class="paragraphs-items paragraphs-items-field-featured-content paragraphs-items-field-featured-content-full paragraphs-items-full"> <div class="field field-name-field-featured-content field-type-paragraphs field-label-hidden"><div class="field-items"><div class="field-item even"><div class="entity entity-paragraphs-item paragraphs-item-featured-content" about="" typeof=""> <div class="content"> <div class="collapsible group-featured-content field-group-div m-featured-product speed-fast effect-none"> <h3><span class="field-group-format-toggler">Featured Content</span></h3> <div class="field-group-format-wrapper" style="display: block;"><h4 class="group-title-wrapper field-group-html-element"><div class="field field-name-field-featured-title field-type-link-field field-label-hidden"><div class="field-items"><div class="field-item even"><a href="https://www.rndsystems.com/resources/articles/glycosylation-receptor-binding-domain-covid-19-virus-spike-protein">Application Note: Glycosylation of the Receptor Binding Domain of COVID-19 Virus Spike Protein</a></div></div></div></h4><div class="required-fields group-img-wrapper field-group-html-element"><div class="field field-name-field-img field-type-et-image-field field-label-hidden"><div class="field-items"><div class="field-item even"><div class=""> <div class="hero-image-text-content"> <div class="hero-image-text-content-inner"> </div> </div> <img loading="lazy" src="https://resources.rndsystems.com/images/design/glycosylation-featured-750x471.jpg?v=1" class="et-image-image" title="Application Note: Glycosylation of the Receptor Binding Domain of COVID-19 Virus Spike Protein" alt="Application Note: Glycosylation of the Receptor Binding Domain of COVID-19 Virus Spike Protein" /> </div> </div></div></div></div><p class="group-featured-content-text field-group-html-element"><div class="field field-name-field-featured-content-text field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">R&D Systems examines the impact of expression system on spike RBD protein glycosylation </div></div></div></p><div class="group-learn-more-wrapper field-group-html-element btn btn-tertiary"><div class="field field-name-field-learn-more field-type-link-field field-label-hidden"><div class="field-items"><div class="field-item even"><a href="https://www.rndsystems.com/resources/articles/glycosylation-receptor-binding-domain-covid-19-virus-spike-protein">Read Application Note</a></div></div></div></div></div></div> </div> </div> </div><div class="field-item odd"><div class="entity entity-paragraphs-item paragraphs-item-featured-content" about="" typeof=""> <div class="content"> <div class="collapsible group-featured-content field-group-div m-featured-product speed-fast effect-none"> <h3><span class="field-group-format-toggler">Featured Content</span></h3> <div class="field-group-format-wrapper" style="display: block;"><h4 class="group-title-wrapper field-group-html-element"><div class="field field-name-field-featured-title field-type-link-field field-label-hidden"><div class="field-items"><div class="field-item even"><a href="https://www.tocris.com/literature/scientific-posters/targeted-protein-degradation" target="_blank">A Chemical Toolbox to Support PROTACs</a></div></div></div></h4><div class="required-fields group-img-wrapper field-group-html-element"><div class="field field-name-field-img field-type-et-image-field field-label-hidden"><div class="field-items"><div class="field-item even"><div class=""> <div class="hero-image-text-content"> <div class="hero-image-text-content-inner"> </div> </div> <img loading="lazy" src="https://resources.rndsystems.com/images/site/featured-tocris-protac-750x471.jpg" class="et-image-image" title="Targeted Protein Degradation Scientific Poster" alt="Targeted Protein Degradation Scientific Poster" /> </div> </div></div></div></div><p class="group-featured-content-text field-group-html-element"><div class="field field-name-field-featured-content-text field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">This poster discusses the generation of a toolbox of building blocks for the development of Degraders</div></div></div></p><div class="group-learn-more-wrapper field-group-html-element btn btn-tertiary"><div class="field field-name-field-learn-more field-type-link-field field-label-hidden"><div class="field-items"><div class="field-item even"><a href="https://www.tocris.com/literature/scientific-posters/targeted-protein-degradation" target="_blank">Download Now</a></div></div></div></div></div></div> </div> </div> </div><div class="field-item even"><div class="entity entity-paragraphs-item paragraphs-item-featured-content" about="" typeof=""> <div class="content"> <div class="collapsible group-featured-content field-group-div m-featured-product speed-fast effect-none"> <h3><span class="field-group-format-toggler">Featured Content</span></h3> <div class="field-group-format-wrapper" style="display: block;"><h4 class="group-title-wrapper field-group-html-element"><div class="field field-name-field-featured-title field-type-link-field field-label-hidden"><div class="field-items"><div class="field-item even"><a href="https://www.rndsystems.com/products/rd-systems-pngase-f-best-choice">R&D Systems PNGase F</a></div></div></div></h4><div class="required-fields group-img-wrapper field-group-html-element"><div class="field field-name-field-img field-type-et-image-field field-label-hidden"><div class="field-items"><div class="field-item even"><div class=""> <div class="hero-image-text-content"> <div class="hero-image-text-content-inner"> </div> </div> <img loading="lazy" src="https://resources.rndsystems.com/images/site/pngase-f-750x471.jpg" class="et-image-image" title="R&D Systems PNGase F" alt="PNGase F enzyme for deglycosylation of proteins" /> </div> </div></div></div></div><p class="group-featured-content-text field-group-html-element"><div class="field field-name-field-featured-content-text field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">PNGase F enzyme for deglycosylation of proteins</div></div></div></p><div class="group-learn-more-wrapper field-group-html-element btn btn-tertiary"><div class="field field-name-field-learn-more field-type-link-field field-label-hidden"><div class="field-items"><div class="field-item even"><a href="https://www.rndsystems.com/products/rd-systems-pngase-f-best-choice">See the data</a></div></div></div></div></div></div> </div> </div> </div><div class="field-item odd"><div class="entity entity-paragraphs-item paragraphs-item-featured-content" about="" typeof=""> <div class="content"> <div class="collapsible group-featured-content field-group-div m-featured-product speed-fast effect-none"> <h3><span class="field-group-format-toggler">Featured Content</span></h3> <div class="field-group-format-wrapper" style="display: block;"><h4 class="group-title-wrapper field-group-html-element"><div class="field field-name-field-featured-title field-type-link-field field-label-hidden"><div class="field-items"><div class="field-item even"><a href="https://www.rndsystems.com/products/new-active-tryptophan-23-dioxygenase-tdo2-indoleamine-23-dioxygenase-ido-and-other">Enzymes of Tryptophan Metabolism</a></div></div></div></h4><div class="required-fields group-img-wrapper field-group-html-element"><div class="field field-name-field-img field-type-et-image-field field-label-hidden"><div class="field-items"><div class="field-item even"><div class=""> <div class="hero-image-text-content"> <div class="hero-image-text-content-inner"> </div> </div> <img loading="lazy" src="https://resources.rndsystems.com/images/site/enzymes-tryptophan-750x471.jpg?v=2" class="et-image-image" alt="Tryptophan metabolism enzymes: IDO1, IDO2, KAT, TDO2" /> </div> </div></div></div></div><p class="group-featured-content-text field-group-html-element"><div class="field field-name-field-featured-content-text field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">Tryptophan metabolism enzymes: IDO1, IDO2, KAT, TDO2</div></div></div></p><div class="group-learn-more-wrapper field-group-html-element btn btn-tertiary"><div class="field field-name-field-learn-more field-type-link-field field-label-hidden"><div class="field-items"><div class="field-item even"><a href="https://www.rndsystems.com/products/new-active-tryptophan-23-dioxygenase-tdo2-indoleamine-23-dioxygenase-ido-and-other">Learn More</a></div></div></div></div></div></div> </div> </div> </div><div class="field-item even"><div class="entity entity-paragraphs-item paragraphs-item-featured-content" about="" typeof=""> <div class="content"> <div class="collapsible group-featured-content field-group-div m-featured-product speed-fast effect-none"> <h3><span class="field-group-format-toggler">Featured Content</span></h3> <div class="field-group-format-wrapper" style="display: block;"><h4 class="group-title-wrapper field-group-html-element"><div class="field field-name-field-featured-title field-type-link-field field-label-hidden"><div class="field-items"><div class="field-item even"><a href="https://www.rndsystems.com/resources/white-paper/novel-method-detecting-terminal-glycans-using-sds-page">New White Paper: Probing Glycans with SDS-Page</a></div></div></div></h4><div class="required-fields group-img-wrapper field-group-html-element"><div class="field field-name-field-img field-type-et-image-field field-label-hidden"><div class="field-items"><div class="field-item even"><div class=""> <div class="hero-image-text-content"> <div class="hero-image-text-content-inner"> </div> </div> <img loading="lazy" src="https://resources.rndsystems.com/images/site/probing-glycans-sdspage-750x471.jpg" class="et-image-image" alt="White Paper: Probing Glycans with SDS-PAGE" /> </div> </div></div></div></div><p class="group-featured-content-text field-group-html-element"><div class="field field-name-field-featured-content-text field-type-text field-label-hidden"><div class="field-items"><div class="field-item even">White Paper: Probing Glycans with SDS-PAGE</div></div></div></p><div class="group-learn-more-wrapper field-group-html-element btn btn-tertiary"><div class="field field-name-field-learn-more field-type-link-field field-label-hidden"><div class="field-items"><div class="field-item even"><a href="https://www.rndsystems.com/resources/white-paper/novel-method-detecting-terminal-glycans-using-sds-page">Download White Paper</a></div></div></div></div></div></div> </div> 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