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<span class="vector-toc-numb">2</span> <span>Structure</span> </div> </a> <ul id="toc-Structure-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Ligand" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Ligand"> <div class="vector-toc-text"> <span class="vector-toc-numb">3</span> <span>Ligand</span> </div> </a> <ul id="toc-Ligand-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Function" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Function"> <div class="vector-toc-text"> <span class="vector-toc-numb">4</span> <span>Function</span> </div> </a> <ul id="toc-Function-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Role_in_cancer" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Role_in_cancer"> <div class="vector-toc-text"> <span class="vector-toc-numb">5</span> <span>Role in cancer</span> </div> </a> <ul id="toc-Role_in_cancer-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-As_a_drug_target" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#As_a_drug_target"> <div class="vector-toc-text"> <span class="vector-toc-numb">6</span> <span>As a drug target</span> </div> </a> <ul id="toc-As_a_drug_target-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-See_also" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#See_also"> <div class="vector-toc-text"> <span class="vector-toc-numb">7</span> <span>See also</span> </div> </a> <ul id="toc-See_also-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-References" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#References"> <div class="vector-toc-text"> <span class="vector-toc-numb">8</span> <span>References</span> </div> </a> <ul id="toc-References-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Further_reading" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Further_reading"> <div class="vector-toc-text"> <span class="vector-toc-numb">9</span> <span>Further reading</span> </div> </a> <ul id="toc-Further_reading-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-External_links" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#External_links"> <div class="vector-toc-text"> <span class="vector-toc-numb">10</span> <span>External links</span> </div> </a> <ul id="toc-External_links-sublist" class="vector-toc-list"> </ul> </li> </ul> </div> </div> </nav> </div> </div> <div class="mw-content-container"> <main id="content" class="mw-body"> <header class="mw-body-header vector-page-titlebar"> <nav aria-label="Contents" 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mw-first-heading"><span class="mw-page-title-main">P-selectin</span></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" > <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="Go to an article in another language. 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href="https://gl.wikipedia.org/wiki/P-selectina" title="P-selectina – Galician" lang="gl" hreflang="gl" data-title="P-selectina" data-language-autonym="Galego" data-language-local-name="Galician" class="interlanguage-link-target"><span>Galego</span></a></li><li class="interlanguage-link interwiki-it mw-list-item"><a href="https://it.wikipedia.org/wiki/P-selectina" title="P-selectina – Italian" lang="it" hreflang="it" data-title="P-selectina" data-language-autonym="Italiano" data-language-local-name="Italian" class="interlanguage-link-target"><span>Italiano</span></a></li><li class="interlanguage-link interwiki-ja mw-list-item"><a href="https://ja.wikipedia.org/wiki/P-%E3%82%BB%E3%83%AC%E3%82%AF%E3%83%81%E3%83%B3" title="P-セレクチン – Japanese" lang="ja" hreflang="ja" data-title="P-セレクチン" data-language-autonym="日本語" data-language-local-name="Japanese" class="interlanguage-link-target"><span>日本語</span></a></li><li class="interlanguage-link interwiki-pl mw-list-item"><a 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style="text-align:center;font-size:125%;font-weight:bold">SELP</th></tr><tr><td colspan="4" style="text-align:center"><span typeof="mw:File"><a href="/wiki/File:Pselectin.PNG" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/c/cb/Pselectin.PNG/250px-Pselectin.PNG" decoding="async" width="250" height="407" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/c/cb/Pselectin.PNG/375px-Pselectin.PNG 1.5x, //upload.wikimedia.org/wikipedia/commons/c/cb/Pselectin.PNG 2x" data-file-width="428" data-file-height="697" /></a></span></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><table style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th colspan="4" style="text-align:center;background-color:#ddd">Available structures</th></tr><tr><th rowspan="2" style="background-color:#c3fdb8;width:43px"><a href="/wiki/Protein_Data_Bank" title="Protein Data Bank">PDB</a></th><td colspan="2" style="background-color:#eee">Ortholog search: <span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ebi.ac.uk/pdbe/searchResults.html?display=both&term=Q01102%20or%20P16109%20or%20A0A024R8Y9">PDBe</a> <a rel="nofollow" class="external text" href="https://www.rcsb.org/search?q=rcsb_polymer_entity_container_identifiers.reference_sequence_identifiers.database_name:UniProt%20AND%20rcsb_polymer_entity_container_identifiers.reference_sequence_identifiers.database_accession:Q01102,P16109,A0A024R8Y9">RCSB</a> </span></td></tr><tr><td><table class="collapsible collapsed" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr style="background-color:#ddd;text-align:center"><th colspan="2">List of PDB id codes</th></tr><tr><td colspan="2" style="background-color:#eee"><p><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1FSB">1FSB</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1G1Q">1G1Q</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1G1R">1G1R</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1G1S">1G1S</a>, <a rel="nofollow" class="external text" href="https://www.rcsb.org/structure/1HES">1HES</a></span></p></td></tr></tbody></table></td></tr></tbody></table></td></tr><tr><th colspan="4" style="text-align:center;background-color:#ddd">Identifiers</th></tr><tr><th scope="row" style="background-color:#c3fdb8"><span class="plainlinks"><a href="/wiki/Gene_nomenclature" title="Gene nomenclature">Aliases</a></span></th><td colspan="3" style="background:#eee"><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/10721">SELP</a></span>, CD62, CD62P, GMP140, GRMP, LECAM3, PADGEM, PSEL, selectin P</td></tr><tr><th scope="row" style="background-color:#c3fdb8">External IDs</th><td colspan="3" style="background-color:#eee"><span class="plainlinks"><a href="/wiki/Mendelian_Inheritance_in_Man" class="mw-redirect" title="Mendelian Inheritance in Man">OMIM</a>: <a rel="nofollow" class="external text" href="https://omim.org/entry/173610">173610</a>; <a href="/wiki/Mouse_Genome_Informatics" title="Mouse Genome Informatics">MGI</a>: <a rel="nofollow" class="external text" href="http://www.informatics.jax.org/marker/MGI:98280">98280</a>; <a href="/wiki/HomoloGene" title="HomoloGene">HomoloGene</a>: <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=homologene&dopt=HomoloGene&list_uids=2260">2260</a>; <a href="/wiki/GeneCards" title="GeneCards">GeneCards</a>: <a rel="nofollow" class="external text" href="https://www.genecards.org/cgi-bin/carddisp.pl?gene=SELP">SELP</a>; <a href="/wiki/Orthologous_MAtrix" title="Orthologous MAtrix">OMA</a>:<a rel="nofollow" class="external text" href="https://omabrowser.org/oma/vps/ENSG00000174175">SELP - orthologs</a></span></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><table class="collapsible collapsed" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th colspan="4" style="text-align:center;background-color:#ddd">Gene location (<a href="/wiki/Human_genome" title="Human genome">Human</a>)</th></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><span typeof="mw:File"><a href="/wiki/File:Ideogram_human_chromosome_1.svg" class="mw-file-description" title="Chromosome 1 (human)"><img alt="Chromosome 1 (human)" src="//upload.wikimedia.org/wikipedia/commons/thumb/d/d6/Ideogram_human_chromosome_1.svg/300px-Ideogram_human_chromosome_1.svg.png" decoding="async" width="300" height="120" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/d6/Ideogram_human_chromosome_1.svg/450px-Ideogram_human_chromosome_1.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/d6/Ideogram_human_chromosome_1.svg/600px-Ideogram_human_chromosome_1.svg.png 2x" data-file-width="474" data-file-height="189" /></a></span></td></tr><tr><th scope="row" width="15%" style="background-color:#c3fdb8"><a href="/wiki/Chromosome" title="Chromosome">Chr.</a></th><td colspan="3" width="85%" style="background-color:#eee"><span class="plainlinks"><a href="/wiki/Chromosome_1_(human)" class="mw-redirect" title="Chromosome 1 (human)">Chromosome 1 (human)</a><sup id="cite_ref-refGRCh38Ensembl_1-0" class="reference"><a href="#cite_note-refGRCh38Ensembl-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup></span></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><div align="center"><div style="position: relative; width: 300px;"><span typeof="mw:File"><a href="/wiki/File:Human_chromosome_1_ideogram.svg" class="mw-file-description" title="Chromosome 1 (human)"><img alt="Chromosome 1 (human)" src="//upload.wikimedia.org/wikipedia/commons/thumb/7/7e/Human_chromosome_1_ideogram.svg/300px-Human_chromosome_1_ideogram.svg.png" decoding="async" width="300" height="58" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/7/7e/Human_chromosome_1_ideogram.svg/450px-Human_chromosome_1_ideogram.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/7/7e/Human_chromosome_1_ideogram.svg/600px-Human_chromosome_1_ideogram.svg.png 2x" data-file-width="1125" data-file-height="216" /></a></span><div style="position: absolute; left: 194.9876452008px; top: 2px; padding: 0;"><span typeof="mw:File"><a href="/wiki/File:HSR_1996_II_3.5e.svg" class="mw-file-description" title="Genomic location for SELP"><img alt="Genomic location for SELP" src="//upload.wikimedia.org/wikipedia/commons/thumb/d/d8/HSR_1996_II_3.5e.svg/14px-HSR_1996_II_3.5e.svg.png" decoding="async" width="14" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/d8/HSR_1996_II_3.5e.svg/21px-HSR_1996_II_3.5e.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/d8/HSR_1996_II_3.5e.svg/28px-HSR_1996_II_3.5e.svg.png 2x" data-file-width="142" data-file-height="142" /></a></span></div><div style="position: absolute; left: 201px; top: 19px; padding: 0;"><span typeof="mw:File"><a href="/wiki/File:Red_rectangle_2x18.png" class="mw-file-description" title="Genomic location for SELP"><img alt="Genomic location for SELP" src="//upload.wikimedia.org/wikipedia/commons/6/6a/Red_rectangle_2x18.png" decoding="async" width="2" height="18" class="mw-file-element" data-file-width="2" data-file-height="18" /></a></span></div></div></div></td></tr><tr><th scope="row" rowspan="2" width="15%" style="background-color:#c3fdb8"><a href="/wiki/Locus_(genetics)" title="Locus (genetics)">Band</a></th><td rowspan="2" width="35%" style="background-color:#eee"><span class="plainlinks">1q24.2</span></td><th scope="row" style="background-color:#c3fdb8">Start</th><td style="background-color:#eee"><span class="plainlinks">169,588,849 <a href="/wiki/Base_pair" title="Base pair">bp</a><sup id="cite_ref-refGRCh38Ensembl_1-1" class="reference"><a href="#cite_note-refGRCh38Ensembl-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup></span></td></tr><tr><th scope="row" style="background-color:#c3fdb8">End</th><td style="background-color:#eee"><span class="plainlinks">169,630,193 <a href="/wiki/Base_pair" title="Base pair">bp</a><sup id="cite_ref-refGRCh38Ensembl_1-2" class="reference"><a href="#cite_note-refGRCh38Ensembl-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup></span></td></tr></tbody></table></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><table class="collapsible collapsed" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th colspan="4" style="text-align:center;background-color:#ddd">Gene location (<a href="/wiki/Laboratory_mouse" title="Laboratory mouse">Mouse</a>)</th></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><span typeof="mw:File"><a href="/wiki/File:Ideogram_house_mouse_chromosome_1.svg" class="mw-file-description" title="Chromosome 1 (mouse)"><img alt="Chromosome 1 (mouse)" src="//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Ideogram_house_mouse_chromosome_1.svg/260px-Ideogram_house_mouse_chromosome_1.svg.png" decoding="async" width="260" height="111" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Ideogram_house_mouse_chromosome_1.svg/390px-Ideogram_house_mouse_chromosome_1.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Ideogram_house_mouse_chromosome_1.svg/520px-Ideogram_house_mouse_chromosome_1.svg.png 2x" data-file-width="470" data-file-height="200" /></a></span></td></tr><tr><th scope="row" width="15%" style="background-color:#c3fdb8"><a href="/wiki/Chromosome" title="Chromosome">Chr.</a></th><td colspan="3" width="85%" style="background-color:#eee"><span class="plainlinks">Chromosome 1 (mouse)<sup id="cite_ref-refGRCm38Ensembl_2-0" class="reference"><a href="#cite_note-refGRCm38Ensembl-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup></span></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><div align="center"><div style="position: relative; width: 300px;"><span typeof="mw:File"><a href="/wiki/File:Ideogram_of_house_mouse_chromosome_1.svg" class="mw-file-description" title="Chromosome 1 (mouse)"><img alt="Chromosome 1 (mouse)" src="//upload.wikimedia.org/wikipedia/commons/thumb/5/5b/Ideogram_of_house_mouse_chromosome_1.svg/300px-Ideogram_of_house_mouse_chromosome_1.svg.png" decoding="async" width="300" height="58" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/5/5b/Ideogram_of_house_mouse_chromosome_1.svg/450px-Ideogram_of_house_mouse_chromosome_1.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/5/5b/Ideogram_of_house_mouse_chromosome_1.svg/600px-Ideogram_of_house_mouse_chromosome_1.svg.png 2x" data-file-width="1200" data-file-height="231" /></a></span><div style="position: absolute; left: 241.31640731808px; top: 2px; padding: 0;"><span typeof="mw:File"><a href="/wiki/File:HSR_1996_II_3.5e.svg" class="mw-file-description" title="Genomic location for SELP"><img alt="Genomic location for SELP" src="//upload.wikimedia.org/wikipedia/commons/thumb/d/d8/HSR_1996_II_3.5e.svg/14px-HSR_1996_II_3.5e.svg.png" decoding="async" width="14" height="14" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/d/d8/HSR_1996_II_3.5e.svg/21px-HSR_1996_II_3.5e.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/d/d8/HSR_1996_II_3.5e.svg/28px-HSR_1996_II_3.5e.svg.png 2x" data-file-width="142" data-file-height="142" /></a></span></div><div style="position: absolute; left: 247.3px; top: 19px; padding: 0;"><span typeof="mw:File"><a href="/wiki/File:Red_rectangle_2x18.png" class="mw-file-description" title="Genomic location for SELP"><img alt="Genomic location for SELP" src="//upload.wikimedia.org/wikipedia/commons/6/6a/Red_rectangle_2x18.png" decoding="async" width="2" height="18" class="mw-file-element" data-file-width="2" data-file-height="18" /></a></span></div></div></div></td></tr><tr><th scope="row" rowspan="2" width="15%" style="background-color:#c3fdb8"><a href="/wiki/Locus_(genetics)" title="Locus (genetics)">Band</a></th><td rowspan="2" width="35%" style="background-color:#eee"><span class="plainlinks">1 H2.2|1 71.42 cM</span></td><th scope="row" style="background-color:#c3fdb8">Start</th><td style="background-color:#eee"><span class="plainlinks">163,942,833 <a href="/wiki/Base_pair" title="Base pair">bp</a><sup id="cite_ref-refGRCm38Ensembl_2-1" class="reference"><a href="#cite_note-refGRCm38Ensembl-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup></span></td></tr><tr><th scope="row" style="background-color:#c3fdb8">End</th><td style="background-color:#eee"><span class="plainlinks">163,977,595 <a href="/wiki/Base_pair" title="Base pair">bp</a><sup id="cite_ref-refGRCm38Ensembl_2-2" class="reference"><a href="#cite_note-refGRCm38Ensembl-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup></span></td></tr></tbody></table></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><table class="collapsible collapsed" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th colspan="4" style="text-align:center;background-color:#ddd"><a href="/wiki/Gene_expression" title="Gene expression">RNA expression</a> pattern</th></tr><tr><th scope="row" style="background-color:#c3fdb8"><a rel="nofollow" class="external text" href="https://www.bgee.org/">Bgee</a></th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th><b><a href="/wiki/Human_genome" title="Human genome">Human</a></b></th><th><b><a href="/wiki/Laboratory_mouse" title="Laboratory mouse">Mouse</a> (ortholog)</b></th></tr><tr><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:center"><tbody><tr><td colspan="1"><span class="plainlinks" style="margin:-3px"><a rel="nofollow" class="external text" href="https://www.bgee.org/gene/ENSG00000174175">Top expressed in</a></span></td></tr><tr><td colspan="1"><div class="plainlinks" style="margin:-12px 0px -10px 0px"><ul style="line-height:15%;margin:9px"><li style="line-height: 137%;">right coronary artery</li><br /><li style="line-height: 137%;">monocyte</li><br /><li style="line-height: 137%;">left uterine tube</li><br /><li style="line-height: 137%;">olfactory zone of nasal mucosa</li><br /><li style="line-height: 137%;">upper lobe of left lung</li><br /><li style="line-height: 137%;">gastric mucosa</li><br /><li style="line-height: 137%;">gallbladder</li><br /><li style="line-height: 137%;">left coronary artery</li><br /><li style="line-height: 137%;">canal of the cervix</li><br /><li style="line-height: 137%;">appendix</li></ul></div></td></tr></tbody></table></td><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:center"><tbody><tr><td colspan="1"><span class="plainlinks" style="margin:-3px"><a rel="nofollow" class="external text" href="https://www.bgee.org/gene/ENSMUSG00000026580">Top expressed in</a></span></td></tr><tr><td colspan="1"><div class="plainlinks" style="margin:-12px 0px -10px 0px"><ul style="line-height:15%;margin:9px"><li style="line-height: 137%;">endothelial cell of lymphatic vessel</li><br /><li style="line-height: 137%;">zygote</li><br /><li style="line-height: 137%;">secondary oocyte</li><br /><li style="line-height: 137%;">granulocyte</li><br /><li style="line-height: 137%;">primary oocyte</li><br /><li style="line-height: 137%;">blood</li><br /><li style="line-height: 137%;">embryo</li><br /><li style="line-height: 137%;">ankle joint</li><br /><li style="line-height: 137%;">tibiofemoral joint</li><br /><li style="line-height: 137%;">ankle</li></ul></div></td></tr></tbody></table></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.bgee.org/gene/ENSG00000174175">More reference expression data</a></span></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:#c3fdb8"><a rel="nofollow" class="external text" href="http://biogps.org/">BioGPS</a></th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><td colspan="4" style="text-align:center;background-color:#eee"><span typeof="mw:File"><a href="/wiki/File:PBB_GE_SELP_206049_at_fs.png" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/1/14/PBB_GE_SELP_206049_at_fs.png/250px-PBB_GE_SELP_206049_at_fs.png" decoding="async" width="250" height="181" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/1/14/PBB_GE_SELP_206049_at_fs.png/375px-PBB_GE_SELP_206049_at_fs.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/1/14/PBB_GE_SELP_206049_at_fs.png/500px-PBB_GE_SELP_206049_at_fs.png 2x" data-file-width="732" data-file-height="530" /></a></span></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><span class="plainlinks"><a rel="nofollow" class="external text" href="http://biogps.org/gene/6403/">More reference expression data</a></span></td></tr></tbody></table></td></tr></tbody></table></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><table class="collapsible collapsed" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th colspan="4" style="text-align:center;background-color:#ddd"><a href="/wiki/Gene_ontology" class="mw-redirect" title="Gene ontology">Gene ontology</a></th></tr><tr><td style="background-color:#c3fdb8;font-weight:bold">Molecular function</td><td style="background-color:#eee"><div class="plainlinks"> <ul><li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0008201">heparin binding</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0070492">oligosaccharide binding</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0001530">lipopolysaccharide binding</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0048306">calcium-dependent protein binding</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0043208">glycosphingolipid binding</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0042806">fucose binding</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0030246">carbohydrate binding</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0033691">sialic acid binding</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0005515">protein binding</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0005509">calcium ion binding</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0046872">metal ion binding</a></li></ul> </div></td></tr><tr><td style="background-color:#c3fdb8;font-weight:bold">Cellular component</td><td style="background-color:#eee"><div class="plainlinks"> <ul><li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0016021">integral component of membrane</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0016020">membrane</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0031092">platelet alpha granule membrane</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0031088">platelet dense granule membrane</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0009897">external side of plasma membrane</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0005615">extracellular space</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0005887">integral component of plasma membrane</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0005886">plasma membrane</a></li></ul> </div></td></tr><tr><td style="background-color:#c3fdb8;font-weight:bold">Biological process</td><td style="background-color:#eee"><div class="plainlinks"> <ul><li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0007159">leukocyte cell-cell adhesion</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0007157">heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0002687">positive regulation of leukocyte migration</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0002576">platelet degranulation</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0033623">regulation of integrin activation</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0007155">cell adhesion</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0050829">defense response to Gram-negative bacterium</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0014068">positive regulation of phosphatidylinositol 3-kinase signaling</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0006954">inflammatory response</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0035584">calcium-mediated signaling using intracellular calcium source</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0010572">positive regulation of platelet activation</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0050900">leukocyte migration</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0032496">response to lipopolysaccharide</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0016339">calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules</a></li> <li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0050901">leukocyte tethering or rolling</a></li></ul> </div></td></tr><tr><td colspan="4" style="background-color:#eee;text-align:center">Sources:<a rel="nofollow" class="external text" href="http://amigo.geneontology.org/">Amigo</a> / <a rel="nofollow" class="external text" href="https://www.ebi.ac.uk/QuickGO/">QuickGO</a></td></tr></tbody></table></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><table class="collapsible" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th colspan="4" style="text-align:center;background-color:#ddd"><a href="/wiki/Orthologs" class="mw-redirect" title="Orthologs">Orthologs</a></th></tr><tr><th scope="row" style="background-color:#c3fdb8">Species</th><td><b>Human</b></td><td><b>Mouse</b></td></tr><tr><th scope="row" style="background-color:#c3fdb8"><a href="/wiki/Entrez" title="Entrez">Entrez</a></th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=retrieve&dopt=default&list_uids=6403&rn=1">6403</a></p></td></tr></tbody></table></td><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=retrieve&dopt=default&list_uids=20344&rn=1">20344</a></p></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:#c3fdb8"><a href="/wiki/Ensembl" class="mw-redirect" title="Ensembl">Ensembl</a></th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="http://www.ensembl.org/Homo_sapiens/geneview?gene=ENSG00000174175;db=core">ENSG00000174175</a></p></td></tr></tbody></table></td><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="http://www.ensembl.org/Mus_musculus/geneview?gene=ENSMUSG00000026580;db=core">ENSMUSG00000026580</a></p></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:#c3fdb8"><a href="/wiki/UniProt" title="UniProt">UniProt</a></th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="https://www.uniprot.org/uniprot/P16109">P16109</a></p></td></tr></tbody></table></td><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="https://www.uniprot.org/uniprot/Q01102">Q01102</a></p></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:#c3fdb8">RefSeq (mRNA)</th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1" class="plainlinks"></th></tr><tr><td colspan="1"><p><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_003005">NM_003005</a></span></p></td></tr></tbody></table></td><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1" class="plainlinks"></th></tr><tr><td colspan="1"><p><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_011347">NM_011347</a></span></p></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:#c3fdb8">RefSeq (protein)</th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1" class="plainlinks"></th></tr><tr><td colspan="1"><p><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_002996">NP_002996</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_002996.2">NP_002996.2</a></span></p></td></tr></tbody></table></td><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1" class="plainlinks"></th></tr><tr><td colspan="1"><p><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NP_035477">NP_035477</a></span></p></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:#c3fdb8">Location (UCSC)</th><td><span class="plainlinks"><a rel="nofollow" class="external text" href="https://genome.ucsc.edu/cgi-bin/hgTracks?org=Human&db=hg38&position=chr1:169588849-169630193">Chr 1: 169.59 – 169.63 Mb</a></span></td><td><span class="plainlinks"><a rel="nofollow" class="external text" href="https://genome.ucsc.edu/cgi-bin/hgTracks?org=Mouse&db=mm0&position=chr1:163942833-163977595">Chr 1: 163.94 – 163.98 Mb</a></span></td></tr><tr><th scope="row" style="background-color:#c3fdb8"><a href="/wiki/PubMed" title="PubMed">PubMed</a> search</th><td><span class="plainlinks"><sup id="cite_ref-3" class="reference"><a href="#cite_note-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup></span></td><td><span class="plainlinks"><sup id="cite_ref-4" class="reference"><a href="#cite_note-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup></span></td></tr></tbody></table></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><a href="/wiki/Wikidata" title="Wikidata">Wikidata</a></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><table style="padding:0;border:none;margin:0;width:100%;text-align:center"><tbody><tr><td colspan="2" style="background-color:#eee;text-align:center"><a href="https://www.wikidata.org/wiki/Q14881072" class="extiw" title="d:Q14881072">View/Edit Human</a></td><td colspan="2" style="background-color:#eee;text-align:center"><a href="https://www.wikidata.org/wiki/Q14881074" class="extiw" title="d:Q14881074">View/Edit Mouse</a></td></tr></tbody></table></td></tr></tbody></table> <p><b>P-selectin</b> is a <a href="/wiki/Type-1_transmembrane_protein" class="mw-redirect" title="Type-1 transmembrane protein">type-1 transmembrane protein</a> that in humans is encoded by the <b>SELP</b> <a href="/wiki/Gene" title="Gene">gene</a>.<sup id="cite_ref-pmid1375831_5-0" class="reference"><a href="#cite_note-pmid1375831-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup> </p><p>P-selectin functions as a <a href="/wiki/Cell_adhesion_molecule" title="Cell adhesion molecule">cell adhesion molecule</a> (CAM) on the surfaces of activated <a href="/wiki/Endothelial" class="mw-redirect" title="Endothelial">endothelial</a> cells, which line the inner surface of blood vessels, and activated <a href="/wiki/Platelets" class="mw-redirect" title="Platelets">platelets</a>. In unactivated endothelial cells, it is stored in <a href="/wiki/Granule_(cell_biology)" title="Granule (cell biology)">granules</a> called <a href="/wiki/Weibel-Palade_bodies" class="mw-redirect" title="Weibel-Palade bodies">Weibel-Palade bodies</a>. In unactivated platelets P-selectin is stored in <a href="/wiki/Platelet_alpha-granule" class="mw-redirect" title="Platelet alpha-granule">α-granules</a>. </p><p>Other names for P-selectin include CD62P, Granule Membrane Protein 140 (GMP-140), and Platelet Activation-Dependent Granule to External Membrane Protein (PADGEM). It was first identified in endothelial cells in 1989.<sup id="cite_ref-pmid2472431_6-0" class="reference"><a href="#cite_note-pmid2472431-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup> </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="Gene_and_regulation">Gene and regulation</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=P-selectin&action=edit&section=1" title="Edit section: Gene and regulation"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>P-selectin is located on chromosome 1q21-q24, spans > 50 kb and contains 17 <a href="/wiki/Exon" title="Exon">exons</a> in humans.<sup id="cite_ref-pmid9668170_7-0" class="reference"><a href="#cite_note-pmid9668170-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup> P-selectin is constitutively expressed in megakaryocytes (the precursor of platelets) and endothelial cells.<sup id="cite_ref-pmid9545353_8-0" class="reference"><a href="#cite_note-pmid9545353-8"><span class="cite-bracket">[</span>8<span class="cite-bracket">]</span></a></sup> P-selectin expression is induced by two distinct mechanisms. First, P-selectin is synthesized by megakaryocytes and endothelial cells, where it is sorted into the membranes of secretory granules.<sup id="cite_ref-pmid1378326_9-0" class="reference"><a href="#cite_note-pmid1378326-9"><span class="cite-bracket">[</span>9<span class="cite-bracket">]</span></a></sup> When <a href="/wiki/Megakaryocyte" title="Megakaryocyte">megakaryocytes</a> and endothelial cells are activated by agonists such as <a href="/wiki/Thrombin" title="Thrombin">thrombin</a>, P-selectin is rapidly translocated to the <a href="/wiki/Plasma_membrane" class="mw-redirect" title="Plasma membrane">plasma membrane</a> from <a href="/wiki/Granule_(cell_biology)" title="Granule (cell biology)">granules</a>.<sup id="cite_ref-pmid2470733_10-0" class="reference"><a href="#cite_note-pmid2470733-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup> Secondly, increased levels of P-selectin mRNA and protein are induced by inflammatory mediators such as tumor necrosis factor-a (TNF-a), LPS, and interleukin-4 (IL-4). Although TNF-a and LPS increase levels of both mRNA and protein in murine models, they do not appear to affect mRNA in human endothelial cells, while IL-4 increases P-selectin transcription in both species.<sup id="cite_ref-pmid7683689_11-0" class="reference"><a href="#cite_note-pmid7683689-11"><span class="cite-bracket">[</span>11<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-12" class="reference"><a href="#cite_note-12"><span class="cite-bracket">[</span>12<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-13" class="reference"><a href="#cite_note-13"><span class="cite-bracket">[</span>13<span class="cite-bracket">]</span></a></sup> The elevated synthesis of P-selectin may play an important role in the delivery of protein to the cell surface. In ischemic stroke patients, plasma P-selectin concentration was reported to be highly correlated to plasminogen activator inhibitor-1 activity and tissue plasminogen activator activity.<sup id="cite_ref-pmid15916851_14-0" class="reference"><a href="#cite_note-pmid15916851-14"><span class="cite-bracket">[</span>14<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Structure">Structure</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=P-selectin&action=edit&section=2" title="Edit section: Structure"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>P-selectin is found in endothelial cells and platelets where it is stored in <a href="/wiki/Weibel%E2%80%93Palade_body" title="Weibel–Palade body">Weibel-Palade bodies</a> and <a href="/wiki/Platelet_alpha-granule" class="mw-redirect" title="Platelet alpha-granule">α-granules</a>, respectively. In response to inflammatory <a href="/wiki/Cytokine" title="Cytokine">cytokines</a> such as <a href="/wiki/Interleukin-4" class="mw-redirect" title="Interleukin-4">IL-4</a> and <a href="/wiki/Interleukin_13" title="Interleukin 13">IL-13</a>, P-selectin is <a href="/wiki/Protein_translocation#Protein_translocation" class="mw-redirect" title="Protein translocation">translocated</a> to the <a href="/wiki/Cell_membrane" title="Cell membrane">plasma membrane</a> in <a href="/wiki/Endothelial" class="mw-redirect" title="Endothelial">endothelial</a> cells.<sup id="cite_ref-pmid10807781_15-0" class="reference"><a href="#cite_note-pmid10807781-15"><span class="cite-bracket">[</span>15<span class="cite-bracket">]</span></a></sup> The <a href="/wiki/Extracellular" class="mw-redirect" title="Extracellular">extracellular</a> region of P-selectin is composed of three different domains like other selectin types; a <a href="/wiki/C-type_lectin" title="C-type lectin">C-type lectin</a>-like domain in the <a href="/wiki/N-terminus" title="N-terminus">N-terminus</a>, an <a href="/wiki/EGF-like_domain" title="EGF-like domain">EGF-like domain</a> and a <a href="/wiki/CUB_domain" title="CUB domain">complement-binding protein-like domains</a> (same as complement regulatory proteins: CRP) having short consensus repeats (~60 amino acids). The number of CRP repeats is the major feature differentiating the type of selectin in extracellular region. In human, P-selectin has nine repeats while <a href="/wiki/E-selectin" title="E-selectin">E-selectin</a> contains six and <a href="/wiki/L-selectin" title="L-selectin">L-selectin</a> has only two. P-selectin is anchored in transmembrane region that is followed by a short <a href="/wiki/Cytoplasmic" class="mw-redirect" title="Cytoplasmic">cytoplasmic</a> tail region.<sup id="cite_ref-pmid9922371_16-0" class="reference"><a href="#cite_note-pmid9922371-16"><span class="cite-bracket">[</span>16<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Ligand">Ligand</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=P-selectin&action=edit&section=3" title="Edit section: Ligand"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>The primary ligand for P-selectin is P-selectin glycoprotein ligand-1 (<a href="/wiki/PSGL-1" class="mw-redirect" title="PSGL-1">PSGL-1</a>) which is expressed on almost all leukocytes, although P-selectin also binds to <a href="/wiki/Heparan_sulfate" title="Heparan sulfate">heparan sulfate</a> and <a href="/wiki/Fucoidan" title="Fucoidan">fucoidans</a>. PSGL-1 is situated on various <a href="/wiki/Hematopoietic_stem_cell" title="Hematopoietic stem cell">hematopoietic cells</a> such as <a href="/wiki/Neutrophil" title="Neutrophil">neutrophils</a>, <a href="/wiki/Eosinophil" title="Eosinophil">eosinophils</a>, <a href="/wiki/Lymphocyte" title="Lymphocyte">lymphocytes</a>, and <a href="/wiki/Monocyte" title="Monocyte">monocytes</a>, in which it mediates tethering and adhesion of these cells. However, PSGL-1 is not specific for P-selectin, as it can also function as a ligand for both E- and L-selectin.<sup id="cite_ref-pmid9732297_17-0" class="reference"><a href="#cite_note-pmid9732297-17"><span class="cite-bracket">[</span>17<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Function">Function</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=P-selectin&action=edit&section=4" title="Edit section: Function"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>P-selectin plays an essential role in the initial recruitment of <a href="/wiki/Leukocytes" class="mw-redirect" title="Leukocytes">leukocytes</a> (<a href="/wiki/White_blood_cells" class="mw-redirect" title="White blood cells">white blood cells</a>) to the site of injury during <a href="/wiki/Inflammation" title="Inflammation">inflammation</a>. When endothelial cells are <a href="/wiki/Endothelial_activation" title="Endothelial activation">activated</a> by molecules such as histamine or thrombin during inflammation, P-selectin moves from an internal cell location to the endothelial cell surface. </p><p><a href="/wiki/Thrombin" title="Thrombin">Thrombin</a> is one trigger which can stimulate endothelial-cell release of P-selectin and recent studies suggest an additional Ca<sup>2+</sup>-independent pathway involved in the release of P-selectin.<sup id="cite_ref-pmid16332977_18-0" class="reference"><a href="#cite_note-pmid16332977-18"><span class="cite-bracket">[</span>18<span class="cite-bracket">]</span></a></sup> </p><p>Ligands for P-selectin on eosinophils and neutrophils are similar sialylated, <a href="/wiki/Protease" title="Protease">protease</a>-sensitive, endo-beta-galactosidase-resistant structures, clearly different from those reported for E-selectin, and suggest disparate roles for P-selectin and E-selectin during recruitment during inflammatory responses.<sup id="cite_ref-pmid7532979_19-0" class="reference"><a href="#cite_note-pmid7532979-19"><span class="cite-bracket">[</span>19<span class="cite-bracket">]</span></a></sup> </p><p>P-selectin is also very important in the recruitment and aggregation of platelets at areas of vascular injury. In a quiescent platelet, P-selectin is located on the inner wall of α-granules. Platelet activation (through agonists such as thrombin, Type II collagen and ADP) results in "membrane flipping" where the platelet releases α- and dense granules and the inner walls of the granules are exposed on the outside of the cell. The P-selectin then promotes platelet aggregation through platelet-fibrin and platelet-platelet binding. </p><p>P-selectin attaches to the <a href="/wiki/Actin" title="Actin">actin</a> cytoskeleton through <a href="/w/index.php?title=Anchor_proteins&action=edit&redlink=1" class="new" title="Anchor proteins (page does not exist)">anchor proteins</a> that are still poorly characterized.<sup id="cite_ref-20" class="reference"><a href="#cite_note-20"><span class="cite-bracket">[</span>20<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Role_in_cancer">Role in cancer</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=P-selectin&action=edit&section=5" title="Edit section: Role in cancer"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>P-selectin has a functional role in tumour metastasis similar to <a href="/wiki/E-selectin" title="E-selectin">E-selectin</a>.<sup id="cite_ref-pmid20010946_21-0" class="reference"><a href="#cite_note-pmid20010946-21"><span class="cite-bracket">[</span>21<span class="cite-bracket">]</span></a></sup> P-selectin is expressed on the surface of both stimulated endothelial cells and activated <a href="/wiki/Platelets" class="mw-redirect" title="Platelets">platelets</a>, and helps cancer cells invade into the bloodstream for metastasis and provides local multiple growth factors, respectively.<sup id="cite_ref-pmid16648968_22-0" class="reference"><a href="#cite_note-pmid16648968-22"><span class="cite-bracket">[</span>22<span class="cite-bracket">]</span></a></sup> Moreover, platelets facilitate tumor metastasis by forming complexes with tumour cells and leukocytes in the vasculature, thus preventing recognition by macrophages. This is thought to contribute to the seeding of tumour microemboli in distant organs.<sup id="cite_ref-pmid11248082_23-0" class="reference"><a href="#cite_note-pmid11248082-23"><span class="cite-bracket">[</span>23<span class="cite-bracket">]</span></a></sup> In vivo mice experiments have shown that a reduction in circulating platelets could reduce cancer metastasis.<sup id="cite_ref-pmid6386144_24-0" class="reference"><a href="#cite_note-pmid6386144-24"><span class="cite-bracket">[</span>24<span class="cite-bracket">]</span></a></sup> </p><p>The <a href="/wiki/Oligosaccharide" title="Oligosaccharide">oligosaccharide</a> <a href="/wiki/Sialic_acid" title="Sialic acid">sialylated</a> <a href="/wiki/Lewis_x" class="mw-redirect" title="Lewis x">Lewis x</a> (sLe(x)) is expressed on the surface of tumor cells and can be recognized by E-selectin and P-selectin, playing on a key role in metastasis of the tumor. However, in the <a href="/wiki/4T1" title="4T1">4T1</a> breast cancer <a href="/wiki/Cell_culture" title="Cell culture">cell line</a>, E-selectin reactivity is sLe(x) dependent while P-selectin reactivity is sLe(x)-independent, suggesting P-selectin binding is <a href="/wiki/Calcium_in_biology" title="Calcium in biology">Ca<sup>2+</sup></a>-independent and <a href="/wiki/Sulfation" title="Sulfation">sulfation</a>-dependent.<sup id="cite_ref-pmid17154173_25-0" class="reference"><a href="#cite_note-pmid17154173-25"><span class="cite-bracket">[</span>25<span class="cite-bracket">]</span></a></sup> One of the sulfated ligands is <a href="/wiki/Chondroitin_sulfate" title="Chondroitin sulfate">chondroitin sulfate</a>, a type of <a href="/wiki/Glycosaminoglycan" title="Glycosaminoglycan">glycosaminoglycan</a> (GAG). Its activity in tumor metastasis has been probed by the addition of <a href="/wiki/Heparin" title="Heparin">heparin</a> that functions to blocks tumor metastasis. In addition to GAGs, <a href="/wiki/Mucin" title="Mucin">mucin</a> is of interest in P-selectin mediated tumor metastasis.<sup id="cite_ref-pmid17043066_26-0" class="reference"><a href="#cite_note-pmid17043066-26"><span class="cite-bracket">[</span>26<span class="cite-bracket">]</span></a></sup> Selective removal of mucin results in reduced interaction between P-selectin and platelets in vivo and in vitro.<sup id="cite_ref-pmid11248082_23-1" class="reference"><a href="#cite_note-pmid11248082-23"><span class="cite-bracket">[</span>23<span class="cite-bracket">]</span></a></sup> </p><p>Heparin has long been known to represent antiheparanase activity that is to keep an endoglycosidase from degrading heparan sulfate, one of the glycosaminoglycans, and to effectively inhibit P-selectin.<sup id="cite_ref-pmid2955820_27-0" class="reference"><a href="#cite_note-pmid2955820-27"><span class="cite-bracket">[</span>27<span class="cite-bracket">]</span></a></sup> Despite a striking effect of heparin on tumor progression shown in a number of clinical trials,<sup id="cite_ref-pmid17408406_28-0" class="reference"><a href="#cite_note-pmid17408406-28"><span class="cite-bracket">[</span>28<span class="cite-bracket">]</span></a></sup> the use of heparin as anti-cancer agent is limited because of its risk, which might induce adverse bleeding complications. Given those reasons, development of new compounds that target P-selectin is now emerging for cancer therapy. Among them, the inhibitory activity of semisynthetic sulfated tri mannose C-C-linked dimers (STMCs) to P-selectin was shown by the attenuation of tumor metastasis in vivo animal model, indicating the inhibition of interaction between tumor cell and endothelial cell is significant for blocking tumor dissemination.<sup id="cite_ref-pmid21532885_29-0" class="reference"><a href="#cite_note-pmid21532885-29"><span class="cite-bracket">[</span>29<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="As_a_drug_target">As a drug target</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=P-selectin&action=edit&section=6" title="Edit section: As a drug target"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p><a href="/wiki/Crizanlizumab" title="Crizanlizumab">Crizanlizumab</a> is a monoclonal antibody against P-selectin.<sup id="cite_ref-NEJM001_30-0" class="reference"><a href="#cite_note-NEJM001-30"><span class="cite-bracket">[</span>30<span class="cite-bracket">]</span></a></sup> which has now been approved by Novartis on November 15, 2019 for the indication of vaso-occlusive crisis in sickle cell patients. </p> <div class="mw-heading mw-heading2"><h2 id="See_also">See also</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=P-selectin&action=edit&section=7" title="Edit section: See also"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a href="/wiki/Selectin" title="Selectin">Selectin</a></li></ul> <div class="mw-heading mw-heading2"><h2 id="References">References</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=P-selectin&action=edit&section=8" title="Edit section: References"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1239543626">.mw-parser-output .reflist{margin-bottom:0.5em;list-style-type:decimal}@media screen{.mw-parser-output .reflist{font-size:90%}}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output .reflist-columns-2{column-width:30em}.mw-parser-output .reflist-columns-3{column-width:25em}.mw-parser-output .reflist-columns{margin-top:0.3em}.mw-parser-output .reflist-columns ol{margin-top:0}.mw-parser-output .reflist-columns li{page-break-inside:avoid;break-inside:avoid-column}.mw-parser-output .reflist-upper-alpha{list-style-type:upper-alpha}.mw-parser-output .reflist-upper-roman{list-style-type:upper-roman}.mw-parser-output .reflist-lower-alpha{list-style-type:lower-alpha}.mw-parser-output .reflist-lower-greek{list-style-type:lower-greek}.mw-parser-output .reflist-lower-roman{list-style-type:lower-roman}</style><div class="reflist reflist-columns references-column-width" style="column-width: 35em;"> <ol class="references"> <li id="cite_note-refGRCh38Ensembl-1"><span class="mw-cite-backlink">^ <a href="#cite_ref-refGRCh38Ensembl_1-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-refGRCh38Ensembl_1-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-refGRCh38Ensembl_1-2"><sup><i><b>c</b></i></sup></a></span> <span class="reference-text"><a rel="nofollow" class="external text" href="http://May2017.archive.ensembl.org/Homo_sapiens/Gene/Summary?db=core;g=ENSG00000174175">GRCh38: Ensembl release 89: ENSG00000174175</a> – <a href="/wiki/Ensembl_genome_database_project" title="Ensembl genome database project">Ensembl</a>, May 2017</span> </li> <li id="cite_note-refGRCm38Ensembl-2"><span class="mw-cite-backlink">^ <a href="#cite_ref-refGRCm38Ensembl_2-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-refGRCm38Ensembl_2-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-refGRCm38Ensembl_2-2"><sup><i><b>c</b></i></sup></a></span> <span class="reference-text"><a rel="nofollow" class="external text" href="http://May2017.archive.ensembl.org/Mus_musculus/Gene/Summary?db=core;g=ENSMUSG00000026580">GRCm38: Ensembl release 89: ENSMUSG00000026580</a> – <a href="/wiki/Ensembl_genome_database_project" title="Ensembl genome database project">Ensembl</a>, May 2017</span> </li> <li id="cite_note-3"><span class="mw-cite-backlink"><b><a href="#cite_ref-3">^</a></b></span> <span class="reference-text"><style data-mw-deduplicate="TemplateStyles:r1238218222">.mw-parser-output cite.citation{font-style:inherit;word-wrap:break-word}.mw-parser-output .citation q{quotes:"\"""\"""'""'"}.mw-parser-output .citation:target{background-color:rgba(0,127,255,0.133)}.mw-parser-output .id-lock-free.id-lock-free a{background:url("//upload.wikimedia.org/wikipedia/commons/6/65/Lock-green.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-limited.id-lock-limited a,.mw-parser-output .id-lock-registration.id-lock-registration a{background:url("//upload.wikimedia.org/wikipedia/commons/d/d6/Lock-gray-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-subscription.id-lock-subscription a{background:url("//upload.wikimedia.org/wikipedia/commons/a/aa/Lock-red-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .cs1-ws-icon a{background:url("//upload.wikimedia.org/wikipedia/commons/4/4c/Wikisource-logo.svg")right 0.1em center/12px no-repeat}body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-free a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-limited a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-registration a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-subscription a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .cs1-ws-icon a{background-size:contain;padding:0 1em 0 0}.mw-parser-output .cs1-code{color:inherit;background:inherit;border:none;padding:inherit}.mw-parser-output .cs1-hidden-error{display:none;color:var(--color-error,#d33)}.mw-parser-output .cs1-visible-error{color:var(--color-error,#d33)}.mw-parser-output .cs1-maint{display:none;color:#085;margin-left:0.3em}.mw-parser-output .cs1-kern-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right{padding-right:0.2em}.mw-parser-output .citation .mw-selflink{font-weight:inherit}@media screen{.mw-parser-output .cs1-format{font-size:95%}html.skin-theme-clientpref-night .mw-parser-output .cs1-maint{color:#18911f}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .cs1-maint{color:#18911f}}</style><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Link&LinkName=gene_pubmed&from_uid=6403">"Human PubMed Reference:"</a>. <i>National Center for Biotechnology Information, U.S. National Library of Medicine</i>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=National+Center+for+Biotechnology+Information%2C+U.S.+National+Library+of+Medicine&rft.atitle=Human+PubMed+Reference%3A&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fsites%2Fentrez%3Fdb%3Dgene%26cmd%3DLink%26LinkName%3Dgene_pubmed%26from_uid%3D6403&rfr_id=info%3Asid%2Fen.wikipedia.org%3AP-selectin" class="Z3988"></span></span> </li> <li id="cite_note-4"><span class="mw-cite-backlink"><b><a href="#cite_ref-4">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Link&LinkName=gene_pubmed&from_uid=20344">"Mouse PubMed Reference:"</a>. <i>National Center for Biotechnology Information, U.S. National Library of Medicine</i>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=National+Center+for+Biotechnology+Information%2C+U.S.+National+Library+of+Medicine&rft.atitle=Mouse+PubMed+Reference%3A&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fsites%2Fentrez%3Fdb%3Dgene%26cmd%3DLink%26LinkName%3Dgene_pubmed%26from_uid%3D20344&rfr_id=info%3Asid%2Fen.wikipedia.org%3AP-selectin" class="Z3988"></span></span> </li> <li id="cite_note-pmid1375831-5"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid1375831_5-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFRyanWorthington1992" class="citation journal cs1">Ryan US, Worthington RE (February 1992). "Cell-cell contact mechanisms". <i>Current Opinion in Immunology</i>. <b>4</b> (1): 33–37. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1016%2F0952-7915%2892%2990120-4">10.1016/0952-7915(92)90120-4</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/1375831">1375831</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Current+Opinion+in+Immunology&rft.atitle=Cell-cell+contact+mechanisms&rft.volume=4&rft.issue=1&rft.pages=33-37&rft.date=1992-02&rft_id=info%3Adoi%2F10.1016%2F0952-7915%2892%2990120-4&rft_id=info%3Apmid%2F1375831&rft.aulast=Ryan&rft.aufirst=US&rft.au=Worthington%2C+RE&rfr_id=info%3Asid%2Fen.wikipedia.org%3AP-selectin" class="Z3988"></span></span> </li> <li id="cite_note-pmid2472431-6"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid2472431_6-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFMcEverBecksteadMooreMarshall-Carlson1989" class="citation journal cs1">McEver RP, Beckstead JH, Moore KL, Marshall-Carlson L, Bainton DF (July 1989). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC303957">"GMP-140, a platelet alpha-granule membrane protein, is also synthesized by vascular endothelial cells and is localized in Weibel-Palade bodies"</a>. <i>The Journal of Clinical Investigation</i>. <b>84</b> (1): 92–99. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1172%2FJCI114175">10.1172/JCI114175</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC303957">303957</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/2472431">2472431</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=The+Journal+of+Clinical+Investigation&rft.atitle=GMP-140%2C+a+platelet+alpha-granule+membrane+protein%2C+is+also+synthesized+by+vascular+endothelial+cells+and+is+localized+in+Weibel-Palade+bodies&rft.volume=84&rft.issue=1&rft.pages=92-99&rft.date=1989-07&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC303957%23id-name%3DPMC&rft_id=info%3Apmid%2F2472431&rft_id=info%3Adoi%2F10.1172%2FJCI114175&rft.aulast=McEver&rft.aufirst=RP&rft.au=Beckstead%2C+JH&rft.au=Moore%2C+KL&rft.au=Marshall-Carlson%2C+L&rft.au=Bainton%2C+DF&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC303957&rfr_id=info%3Asid%2Fen.wikipedia.org%3AP-selectin" class="Z3988"></span></span> </li> <li id="cite_note-pmid9668170-7"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid9668170_7-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFHerrmannRicardNicaudMallet1998" class="citation journal cs1">Herrmann SM, Ricard S, Nicaud V, Mallet C, Evans A, Ruidavets JB, et al. (August 1998). <a rel="nofollow" class="external text" href="https://doi.org/10.1093%2Fhmg%2F7.8.1277">"The P-selectin gene is highly polymorphic: reduced frequency of the Pro715 allele carriers in patients with myocardial infarction"</a>. <i>Human Molecular Genetics</i>. <b>7</b> (8): 1277–1284. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1093%2Fhmg%2F7.8.1277">10.1093/hmg/7.8.1277</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/9668170">9668170</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Human+Molecular+Genetics&rft.atitle=The+P-selectin+gene+is+highly+polymorphic%3A+reduced+frequency+of+the+Pro715+allele+carriers+in+patients+with+myocardial+infarction&rft.volume=7&rft.issue=8&rft.pages=1277-1284&rft.date=1998-08&rft_id=info%3Adoi%2F10.1093%2Fhmg%2F7.8.1277&rft_id=info%3Apmid%2F9668170&rft.aulast=Herrmann&rft.aufirst=SM&rft.au=Ricard%2C+S&rft.au=Nicaud%2C+V&rft.au=Mallet%2C+C&rft.au=Evans%2C+A&rft.au=Ruidavets%2C+JB&rft.au=Arveiler%2C+D&rft.au=Luc%2C+G&rft.au=Cambien%2C+F&rft_id=https%3A%2F%2Fdoi.org%2F10.1093%252Fhmg%252F7.8.1277&rfr_id=info%3Asid%2Fen.wikipedia.org%3AP-selectin" class="Z3988"></span></span> </li> <li id="cite_note-pmid9545353-8"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid9545353_8-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFPanXiaMcEver1998" class="citation journal cs1">Pan J, Xia L, McEver RP (April 1998). <a rel="nofollow" class="external text" href="https://doi.org/10.1074%2Fjbc.273.16.10058">"Comparison of promoters for the murine and human P-selectin genes suggests species-specific and conserved mechanisms for transcriptional regulation in endothelial cells"</a>. <i>The Journal of Biological Chemistry</i>. <b>273</b> (16): 10058–10067. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1074%2Fjbc.273.16.10058">10.1074/jbc.273.16.10058</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/9545353">9545353</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=The+Journal+of+Biological+Chemistry&rft.atitle=Comparison+of+promoters+for+the+murine+and+human+P-selectin+genes+suggests+species-specific+and+conserved+mechanisms+for+transcriptional+regulation+in+endothelial+cells&rft.volume=273&rft.issue=16&rft.pages=10058-10067&rft.date=1998-04&rft_id=info%3Adoi%2F10.1074%2Fjbc.273.16.10058&rft_id=info%3Apmid%2F9545353&rft.aulast=Pan&rft.aufirst=J&rft.au=Xia%2C+L&rft.au=McEver%2C+RP&rft_id=https%3A%2F%2Fdoi.org%2F10.1074%252Fjbc.273.16.10058&rfr_id=info%3Asid%2Fen.wikipedia.org%3AP-selectin" class="Z3988"></span></span> </li> <li id="cite_note-pmid1378326-9"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid1378326_9-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFDisdierMorrisseyFugateBainton1992" class="citation journal cs1">Disdier M, Morrissey JH, Fugate RD, Bainton DF, McEver RP (March 1992). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC275532">"Cytoplasmic domain of P-selectin (CD62) contains the signal for sorting into the regulated secretory pathway"</a>. <i>Molecular Biology of the Cell</i>. <b>3</b> (3): 309–321. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1091%2Fmbc.3.3.309">10.1091/mbc.3.3.309</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC275532">275532</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/1378326">1378326</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Molecular+Biology+of+the+Cell&rft.atitle=Cytoplasmic+domain+of+P-selectin+%28CD62%29+contains+the+signal+for+sorting+into+the+regulated+secretory+pathway&rft.volume=3&rft.issue=3&rft.pages=309-321&rft.date=1992-03&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC275532%23id-name%3DPMC&rft_id=info%3Apmid%2F1378326&rft_id=info%3Adoi%2F10.1091%2Fmbc.3.3.309&rft.aulast=Disdier&rft.aufirst=M&rft.au=Morrissey%2C+JH&rft.au=Fugate%2C+RD&rft.au=Bainton%2C+DF&rft.au=McEver%2C+RP&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC275532&rfr_id=info%3Asid%2Fen.wikipedia.org%3AP-selectin" class="Z3988"></span></span> </li> <li id="cite_note-pmid2470733-10"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid2470733_10-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFHattoriHamiltonFugateMcEver1989" class="citation journal cs1">Hattori R, Hamilton KK, Fugate RD, McEver RP, Sims PJ (May 1989). <a rel="nofollow" class="external text" href="https://doi.org/10.1016%2FS0021-9258%2818%2983104-0">"Stimulated secretion of endothelial von Willebrand factor is accompanied by rapid redistribution to the cell surface of the intracellular granule membrane protein GMP-140"</a>. <i>The Journal of Biological Chemistry</i>. <b>264</b> (14): 7768–7771. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1016%2FS0021-9258%2818%2983104-0">10.1016/S0021-9258(18)83104-0</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/2470733">2470733</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=The+Journal+of+Biological+Chemistry&rft.atitle=Stimulated+secretion+of+endothelial+von+Willebrand+factor+is+accompanied+by+rapid+redistribution+to+the+cell+surface+of+the+intracellular+granule+membrane+protein+GMP-140&rft.volume=264&rft.issue=14&rft.pages=7768-7771&rft.date=1989-05&rft_id=info%3Adoi%2F10.1016%2FS0021-9258%2818%2983104-0&rft_id=info%3Apmid%2F2470733&rft.aulast=Hattori&rft.aufirst=R&rft.au=Hamilton%2C+KK&rft.au=Fugate%2C+RD&rft.au=McEver%2C+RP&rft.au=Sims%2C+PJ&rft_id=https%3A%2F%2Fdoi.org%2F10.1016%252FS0021-9258%252818%252983104-0&rfr_id=info%3Asid%2Fen.wikipedia.org%3AP-selectin" class="Z3988"></span></span> </li> <li id="cite_note-pmid7683689-11"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid7683689_11-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFHahneJägerIsenmannHallmann1993" class="citation journal cs1">Hahne M, Jäger U, Isenmann S, Hallmann R, Vestweber D (May 1993). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2119562">"Five tumor necrosis factor-inducible cell adhesion mechanisms on the surface of mouse endothelioma cells mediate the binding of leukocytes"</a>. <i>The Journal of Cell Biology</i>. <b>121</b> (3): 655–664. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1083%2Fjcb.121.3.655">10.1083/jcb.121.3.655</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2119562">2119562</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/7683689">7683689</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=The+Journal+of+Cell+Biology&rft.atitle=Five+tumor+necrosis+factor-inducible+cell+adhesion+mechanisms+on+the+surface+of+mouse+endothelioma+cells+mediate+the+binding+of+leukocytes&rft.volume=121&rft.issue=3&rft.pages=655-664&rft.date=1993-05&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2119562%23id-name%3DPMC&rft_id=info%3Apmid%2F7683689&rft_id=info%3Adoi%2F10.1083%2Fjcb.121.3.655&rft.aulast=Hahne&rft.aufirst=M&rft.au=J%C3%A4ger%2C+U&rft.au=Isenmann%2C+S&rft.au=Hallmann%2C+R&rft.au=Vestweber%2C+D&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2119562&rfr_id=info%3Asid%2Fen.wikipedia.org%3AP-selectin" class="Z3988"></span></span> </li> <li id="cite_note-12"><span class="mw-cite-backlink"><b><a href="#cite_ref-12">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFLiuMinerYagoYao2010" class="citation journal cs1">Liu Z, Miner JJ, Yago T, Yao L, Lupu F, Xia L, et al. (December 2010). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005233">"Differential regulation of human and murine P-selectin expression and function in vivo"</a>. <i>The Journal of Experimental Medicine</i>. <b>207</b> (13): 2975–2987. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1084%2Fjem.20101545">10.1084/jem.20101545</a></span>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005233">3005233</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/21149548">21149548</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=The+Journal+of+Experimental+Medicine&rft.atitle=Differential+regulation+of+human+and+murine+P-selectin+expression+and+function+in+vivo&rft.volume=207&rft.issue=13&rft.pages=2975-2987&rft.date=2010-12&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3005233%23id-name%3DPMC&rft_id=info%3Apmid%2F21149548&rft_id=info%3Adoi%2F10.1084%2Fjem.20101545&rft.aulast=Liu&rft.aufirst=Z&rft.au=Miner%2C+JJ&rft.au=Yago%2C+T&rft.au=Yao%2C+L&rft.au=Lupu%2C+F&rft.au=Xia%2C+L&rft.au=McEver%2C+RP&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3005233&rfr_id=info%3Asid%2Fen.wikipedia.org%3AP-selectin" class="Z3988"></span></span> </li> <li id="cite_note-13"><span class="mw-cite-backlink"><b><a href="#cite_ref-13">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFPanésPerryGranger1999" class="citation journal cs1">Panés J, Perry M, Granger DN (February 1999). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1565837">"Leukocyte-endothelial cell adhesion: avenues for therapeutic intervention"</a>. <i>British Journal of Pharmacology</i>. <b>126</b> (3): 537–550. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1038%2Fsj.bjp.0702328">10.1038/sj.bjp.0702328</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1565837">1565837</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/10188959">10188959</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=British+Journal+of+Pharmacology&rft.atitle=Leukocyte-endothelial+cell+adhesion%3A+avenues+for+therapeutic+intervention&rft.volume=126&rft.issue=3&rft.pages=537-550&rft.date=1999-02&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC1565837%23id-name%3DPMC&rft_id=info%3Apmid%2F10188959&rft_id=info%3Adoi%2F10.1038%2Fsj.bjp.0702328&rft.aulast=Pan%C3%A9s&rft.aufirst=J&rft.au=Perry%2C+M&rft.au=Granger%2C+DN&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC1565837&rfr_id=info%3Asid%2Fen.wikipedia.org%3AP-selectin" class="Z3988"></span></span> </li> <li id="cite_note-pmid15916851-14"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid15916851_14-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFWangLiLiu2005" class="citation journal cs1">Wang J, Li J, Liu Q (August 2005). "Association between platelet activation and fibrinolysis in acute stroke patients". <i>Neuroscience Letters</i>. <b>384</b> (3): 305–309. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1016%2Fj.neulet.2005.04.090">10.1016/j.neulet.2005.04.090</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/15916851">15916851</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:22979258">22979258</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Neuroscience+Letters&rft.atitle=Association+between+platelet+activation+and+fibrinolysis+in+acute+stroke+patients&rft.volume=384&rft.issue=3&rft.pages=305-309&rft.date=2005-08&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A22979258%23id-name%3DS2CID&rft_id=info%3Apmid%2F15916851&rft_id=info%3Adoi%2F10.1016%2Fj.neulet.2005.04.090&rft.aulast=Wang&rft.aufirst=J&rft.au=Li%2C+J&rft.au=Liu%2C+Q&rfr_id=info%3Asid%2Fen.wikipedia.org%3AP-selectin" class="Z3988"></span></span> </li> <li id="cite_note-pmid10807781-15"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid10807781_15-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFWoltmannMcNultyDewsonSymon2000" class="citation journal cs1">Woltmann G, McNulty CA, Dewson G, Symon FA, Wardlaw AJ (May 2000). "Interleukin-13 induces PSGL-1/P-selectin-dependent adhesion of eosinophils, but not neutrophils, to human umbilical vein endothelial cells under flow". <i>Blood</i>. <b>95</b> (10): 3146–3152. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1182%2Fblood.V95.10.3146">10.1182/blood.V95.10.3146</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/10807781">10807781</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Blood&rft.atitle=Interleukin-13+induces+PSGL-1%2FP-selectin-dependent+adhesion+of+eosinophils%2C+but+not+neutrophils%2C+to+human+umbilical+vein+endothelial+cells+under+flow&rft.volume=95&rft.issue=10&rft.pages=3146-3152&rft.date=2000-05&rft_id=info%3Adoi%2F10.1182%2Fblood.V95.10.3146&rft_id=info%3Apmid%2F10807781&rft.aulast=Woltmann&rft.aufirst=G&rft.au=McNulty%2C+CA&rft.au=Dewson%2C+G&rft.au=Symon%2C+FA&rft.au=Wardlaw%2C+AJ&rfr_id=info%3Asid%2Fen.wikipedia.org%3AP-selectin" class="Z3988"></span></span> </li> <li id="cite_note-pmid9922371-16"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid9922371_16-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFVestweberBlanks1999" class="citation journal cs1">Vestweber D, Blanks JE (January 1999). "Mechanisms that regulate the function of the selectins and their ligands". <i>Physiological Reviews</i>. <b>79</b> (1): 181–213. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1152%2Fphysrev.1999.79.1.181">10.1152/physrev.1999.79.1.181</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/9922371">9922371</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Physiological+Reviews&rft.atitle=Mechanisms+that+regulate+the+function+of+the+selectins+and+their+ligands&rft.volume=79&rft.issue=1&rft.pages=181-213&rft.date=1999-01&rft_id=info%3Adoi%2F10.1152%2Fphysrev.1999.79.1.181&rft_id=info%3Apmid%2F9922371&rft.aulast=Vestweber&rft.aufirst=D&rft.au=Blanks%2C+JE&rfr_id=info%3Asid%2Fen.wikipedia.org%3AP-selectin" class="Z3988"></span></span> </li> <li id="cite_note-pmid9732297-17"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid9732297_17-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFLorenzonVecileNardonFerrero1998" class="citation journal cs1">Lorenzon P, Vecile E, Nardon E, Ferrero E, Harlan JM, Tedesco F, et al. (September 1998). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2149355">"Endothelial cell E- and P-selectin and vascular cell adhesion molecule-1 function as signaling receptors"</a>. <i>The Journal of Cell Biology</i>. <b>142</b> (5): 1381–1391. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1083%2Fjcb.142.5.1381">10.1083/jcb.142.5.1381</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2149355">2149355</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/9732297">9732297</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=The+Journal+of+Cell+Biology&rft.atitle=Endothelial+cell+E-+and+P-selectin+and+vascular+cell+adhesion+molecule-1+function+as+signaling+receptors&rft.volume=142&rft.issue=5&rft.pages=1381-1391&rft.date=1998-09&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2149355%23id-name%3DPMC&rft_id=info%3Apmid%2F9732297&rft_id=info%3Adoi%2F10.1083%2Fjcb.142.5.1381&rft.aulast=Lorenzon&rft.aufirst=P&rft.au=Vecile%2C+E&rft.au=Nardon%2C+E&rft.au=Ferrero%2C+E&rft.au=Harlan%2C+JM&rft.au=Tedesco%2C+F&rft.au=Dobrina%2C+A&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2149355&rfr_id=info%3Asid%2Fen.wikipedia.org%3AP-selectin" class="Z3988"></span></span> </li> <li id="cite_note-pmid16332977-18"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid16332977_18-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFCleatorZhuVaughanHamm2006" class="citation journal cs1">Cleator JH, Zhu WQ, Vaughan DE, Hamm HE (April 2006). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1895372">"Differential regulation of endothelial exocytosis of P-selectin and von Willebrand factor by protease-activated receptors and cAMP"</a>. <i>Blood</i>. <b>107</b> (7): 2736–2744. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1182%2Fblood-2004-07-2698">10.1182/blood-2004-07-2698</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1895372">1895372</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/16332977">16332977</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Blood&rft.atitle=Differential+regulation+of+endothelial+exocytosis+of+P-selectin+and+von+Willebrand+factor+by+protease-activated+receptors+and+cAMP&rft.volume=107&rft.issue=7&rft.pages=2736-2744&rft.date=2006-04&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC1895372%23id-name%3DPMC&rft_id=info%3Apmid%2F16332977&rft_id=info%3Adoi%2F10.1182%2Fblood-2004-07-2698&rft.aulast=Cleator&rft.aufirst=JH&rft.au=Zhu%2C+WQ&rft.au=Vaughan%2C+DE&rft.au=Hamm%2C+HE&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC1895372&rfr_id=info%3Asid%2Fen.wikipedia.org%3AP-selectin" class="Z3988"></span></span> </li> <li id="cite_note-pmid7532979-19"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid7532979_19-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFWeinSterbinskyBickelSchleimer1995" class="citation journal cs1">Wein M, Sterbinsky SA, Bickel CA, Schleimer RP, Bochner BS (March 1995). "Comparison of human eosinophil and neutrophil ligands for P-selectin: ligands for P-selectin differ from those for E-selectin". <i>American Journal of Respiratory Cell and Molecular Biology</i>. <b>12</b> (3): 315–319. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1165%2Fajrcmb.12.3.7532979">10.1165/ajrcmb.12.3.7532979</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/7532979">7532979</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=American+Journal+of+Respiratory+Cell+and+Molecular+Biology&rft.atitle=Comparison+of+human+eosinophil+and+neutrophil+ligands+for+P-selectin%3A+ligands+for+P-selectin+differ+from+those+for+E-selectin&rft.volume=12&rft.issue=3&rft.pages=315-319&rft.date=1995-03&rft_id=info%3Adoi%2F10.1165%2Fajrcmb.12.3.7532979&rft_id=info%3Apmid%2F7532979&rft.aulast=Wein&rft.aufirst=M&rft.au=Sterbinsky%2C+SA&rft.au=Bickel%2C+CA&rft.au=Schleimer%2C+RP&rft.au=Bochner%2C+BS&rfr_id=info%3Asid%2Fen.wikipedia.org%3AP-selectin" class="Z3988"></span></span> </li> <li id="cite_note-20"><span class="mw-cite-backlink"><b><a href="#cite_ref-20">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFMartinelliChenClarkeLyck2013" class="citation journal cs1">Martinelli S, Chen EJ, Clarke F, Lyck R, Affentranger S, Burkhardt JK, et al. (2013). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3619129">"Ezrin/Radixin/Moesin proteins and flotillins cooperate to promote uropod formation in T cells"</a>. <i>Frontiers in Immunology</i>. <b>4</b>: 84. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.3389%2Ffimmu.2013.00084">10.3389/fimmu.2013.00084</a></span>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3619129">3619129</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/23579783">23579783</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Frontiers+in+Immunology&rft.atitle=Ezrin%2FRadixin%2FMoesin+proteins+and+flotillins+cooperate+to+promote+uropod+formation+in+T+cells&rft.volume=4&rft.pages=84&rft.date=2013&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3619129%23id-name%3DPMC&rft_id=info%3Apmid%2F23579783&rft_id=info%3Adoi%2F10.3389%2Ffimmu.2013.00084&rft.aulast=Martinelli&rft.aufirst=S&rft.au=Chen%2C+EJ&rft.au=Clarke%2C+F&rft.au=Lyck%2C+R&rft.au=Affentranger%2C+S&rft.au=Burkhardt%2C+JK&rft.au=Niggli%2C+V&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3619129&rfr_id=info%3Asid%2Fen.wikipedia.org%3AP-selectin" class="Z3988"></span></span> </li> <li id="cite_note-pmid20010946-21"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid20010946_21-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFKöhlerUllrichRichterSchumacher2010" class="citation journal cs1">Köhler S, Ullrich S, Richter U, Schumacher U (February 2010). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822933">"E-/P-selectins and colon carcinoma metastasis: first in vivo evidence for their crucial role in a clinically relevant model of spontaneous metastasis formation in the lung"</a>. <i>British Journal of Cancer</i>. <b>102</b> (3): 602–609. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1038%2Fsj.bjc.6605492">10.1038/sj.bjc.6605492</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822933">2822933</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/20010946">20010946</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=British+Journal+of+Cancer&rft.atitle=E-%2FP-selectins+and+colon+carcinoma+metastasis%3A+first+in+vivo+evidence+for+their+crucial+role+in+a+clinically+relevant+model+of+spontaneous+metastasis+formation+in+the+lung&rft.volume=102&rft.issue=3&rft.pages=602-609&rft.date=2010-02&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2822933%23id-name%3DPMC&rft_id=info%3Apmid%2F20010946&rft_id=info%3Adoi%2F10.1038%2Fsj.bjc.6605492&rft.aulast=K%C3%B6hler&rft.aufirst=S&rft.au=Ullrich%2C+S&rft.au=Richter%2C+U&rft.au=Schumacher%2C+U&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2822933&rfr_id=info%3Asid%2Fen.wikipedia.org%3AP-selectin" class="Z3988"></span></span> </li> <li id="cite_note-pmid16648968-22"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid16648968_22-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFChenGeng2006" class="citation journal cs1">Chen M, Geng JG (2006). "P-selectin mediates adhesion of leukocytes, platelets, and cancer cells in inflammation, thrombosis, and cancer growth and metastasis". <i>Archivum Immunologiae et Therapiae Experimentalis</i>. <b>54</b> (2): 75–84. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1007%2Fs00005-006-0010-6">10.1007/s00005-006-0010-6</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/16648968">16648968</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:33274938">33274938</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Archivum+Immunologiae+et+Therapiae+Experimentalis&rft.atitle=P-selectin+mediates+adhesion+of+leukocytes%2C+platelets%2C+and+cancer+cells+in+inflammation%2C+thrombosis%2C+and+cancer+growth+and+metastasis&rft.volume=54&rft.issue=2&rft.pages=75-84&rft.date=2006&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A33274938%23id-name%3DS2CID&rft_id=info%3Apmid%2F16648968&rft_id=info%3Adoi%2F10.1007%2Fs00005-006-0010-6&rft.aulast=Chen&rft.aufirst=M&rft.au=Geng%2C+JG&rfr_id=info%3Asid%2Fen.wikipedia.org%3AP-selectin" class="Z3988"></span></span> </li> <li id="cite_note-pmid11248082-23"><span class="mw-cite-backlink">^ <a href="#cite_ref-pmid11248082_23-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-pmid11248082_23-1"><sup><i><b>b</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFBorsigWongFeramiscoNadeau2001" class="citation journal cs1">Borsig L, Wong R, Feramisco J, Nadeau DR, Varki NM, Varki A (March 2001). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC30657">"Heparin and cancer revisited: mechanistic connections involving platelets, P-selectin, carcinoma mucins, and tumor metastasis"</a>. <i>Proceedings of the National Academy of Sciences of the United States of America</i>. <b>98</b> (6): 3352–3357. <a href="/wiki/Bibcode_(identifier)" class="mw-redirect" title="Bibcode (identifier)">Bibcode</a>:<a rel="nofollow" class="external text" href="https://ui.adsabs.harvard.edu/abs/2001PNAS...98.3352B">2001PNAS...98.3352B</a>. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1073%2Fpnas.061615598">10.1073/pnas.061615598</a></span>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC30657">30657</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/11248082">11248082</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Proceedings+of+the+National+Academy+of+Sciences+of+the+United+States+of+America&rft.atitle=Heparin+and+cancer+revisited%3A+mechanistic+connections+involving+platelets%2C+P-selectin%2C+carcinoma+mucins%2C+and+tumor+metastasis&rft.volume=98&rft.issue=6&rft.pages=3352-3357&rft.date=2001-03&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC30657%23id-name%3DPMC&rft_id=info%3Apmid%2F11248082&rft_id=info%3Adoi%2F10.1073%2Fpnas.061615598&rft_id=info%3Abibcode%2F2001PNAS...98.3352B&rft.aulast=Borsig&rft.aufirst=L&rft.au=Wong%2C+R&rft.au=Feramisco%2C+J&rft.au=Nadeau%2C+DR&rft.au=Varki%2C+NM&rft.au=Varki%2C+A&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC30657&rfr_id=info%3Asid%2Fen.wikipedia.org%3AP-selectin" class="Z3988"></span></span> </li> <li id="cite_note-pmid6386144-24"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid6386144_24-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFGasic1984" class="citation journal cs1">Gasic GJ (1984). "Role of plasma, platelets, and endothelial cells in tumor metastasis". <i>Cancer and Metastasis Reviews</i>. <b>3</b> (2): 99–114. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1007%2FBF00047657">10.1007/BF00047657</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/6386144">6386144</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:20508207">20508207</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Cancer+and+Metastasis+Reviews&rft.atitle=Role+of+plasma%2C+platelets%2C+and+endothelial+cells+in+tumor+metastasis&rft.volume=3&rft.issue=2&rft.pages=99-114&rft.date=1984&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A20508207%23id-name%3DS2CID&rft_id=info%3Apmid%2F6386144&rft_id=info%3Adoi%2F10.1007%2FBF00047657&rft.aulast=Gasic&rft.aufirst=GJ&rfr_id=info%3Asid%2Fen.wikipedia.org%3AP-selectin" class="Z3988"></span></span> </li> <li id="cite_note-pmid17154173-25"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid17154173_25-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFMonzavi-KarbassiStanleyHenningsJousheghany2007" class="citation journal cs1">Monzavi-Karbassi B, Stanley JS, Hennings L, Jousheghany F, Artaud C, Shaaf S, et al. (March 2007). "Chondroitin sulfate glycosaminoglycans as major P-selectin ligands on metastatic breast cancer cell lines". <i>International Journal of Cancer</i>. <b>120</b> (6): 1179–1191. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1002%2Fijc.22424">10.1002/ijc.22424</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/17154173">17154173</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:39853960">39853960</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=International+Journal+of+Cancer&rft.atitle=Chondroitin+sulfate+glycosaminoglycans+as+major+P-selectin+ligands+on+metastatic+breast+cancer+cell+lines&rft.volume=120&rft.issue=6&rft.pages=1179-1191&rft.date=2007-03&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A39853960%23id-name%3DS2CID&rft_id=info%3Apmid%2F17154173&rft_id=info%3Adoi%2F10.1002%2Fijc.22424&rft.aulast=Monzavi-Karbassi&rft.aufirst=B&rft.au=Stanley%2C+JS&rft.au=Hennings%2C+L&rft.au=Jousheghany%2C+F&rft.au=Artaud%2C+C&rft.au=Shaaf%2C+S&rft.au=Kieber-Emmons%2C+T&rfr_id=info%3Asid%2Fen.wikipedia.org%3AP-selectin" class="Z3988"></span></span> </li> <li id="cite_note-pmid17043066-26"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid17043066_26-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFGarciaCallewaertBorsig2007" class="citation journal cs1">Garcia J, Callewaert N, Borsig L (February 2007). <a rel="nofollow" class="external text" href="https://doi.org/10.1093%2Fglycob%2Fcwl059">"P-selectin mediates metastatic progression through binding to sulfatides on tumor cells"</a>. <i>Glycobiology</i>. <b>17</b> (2): 185–196. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1093%2Fglycob%2Fcwl059">10.1093/glycob/cwl059</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/17043066">17043066</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Glycobiology&rft.atitle=P-selectin+mediates+metastatic+progression+through+binding+to+sulfatides+on+tumor+cells&rft.volume=17&rft.issue=2&rft.pages=185-196&rft.date=2007-02&rft_id=info%3Adoi%2F10.1093%2Fglycob%2Fcwl059&rft_id=info%3Apmid%2F17043066&rft.aulast=Garcia&rft.aufirst=J&rft.au=Callewaert%2C+N&rft.au=Borsig%2C+L&rft_id=https%3A%2F%2Fdoi.org%2F10.1093%252Fglycob%252Fcwl059&rfr_id=info%3Asid%2Fen.wikipedia.org%3AP-selectin" class="Z3988"></span></span> </li> <li id="cite_note-pmid2955820-27"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid2955820_27-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFBar-NerEldorWassermanMatzner1987" class="citation journal cs1">Bar-Ner M, Eldor A, Wasserman L, Matzner Y, Cohen IR, Fuks Z, et al. (August 1987). <a rel="nofollow" class="external text" href="https://doi.org/10.1182%2Fblood.V70.2.551.551">"Inhibition of heparanase-mediated degradation of extracellular matrix heparan sulfate by non-anticoagulant heparin species"</a>. <i>Blood</i>. <b>70</b> (2): 551–557. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1182%2Fblood.V70.2.551.551">10.1182/blood.V70.2.551.551</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/2955820">2955820</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Blood&rft.atitle=Inhibition+of+heparanase-mediated+degradation+of+extracellular+matrix+heparan+sulfate+by+non-anticoagulant+heparin+species&rft.volume=70&rft.issue=2&rft.pages=551-557&rft.date=1987-08&rft_id=info%3Adoi%2F10.1182%2Fblood.V70.2.551.551&rft_id=info%3Apmid%2F2955820&rft.aulast=Bar-Ner&rft.aufirst=M&rft.au=Eldor%2C+A&rft.au=Wasserman%2C+L&rft.au=Matzner%2C+Y&rft.au=Cohen%2C+IR&rft.au=Fuks%2C+Z&rft.au=Vlodavsky%2C+I&rft_id=https%3A%2F%2Fdoi.org%2F10.1182%252Fblood.V70.2.551.551&rfr_id=info%3Asid%2Fen.wikipedia.org%3AP-selectin" class="Z3988"></span></span> </li> <li id="cite_note-pmid17408406-28"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid17408406_28-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFLazo-LangnerGossSpaansRodger2007" class="citation journal cs1">Lazo-Langner A, Goss GD, Spaans JN, Rodger MA (April 2007). <a rel="nofollow" class="external text" href="https://doi.org/10.1111%2Fj.1538-7836.2007.02427.x">"The effect of low-molecular-weight heparin on cancer survival. A systematic review and meta-analysis of randomized trials"</a>. <i>Journal of Thrombosis and Haemostasis</i>. <b>5</b> (4): 729–737. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1111%2Fj.1538-7836.2007.02427.x">10.1111/j.1538-7836.2007.02427.x</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/17408406">17408406</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:7632947">7632947</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Journal+of+Thrombosis+and+Haemostasis&rft.atitle=The+effect+of+low-molecular-weight+heparin+on+cancer+survival.+A+systematic+review+and+meta-analysis+of+randomized+trials&rft.volume=5&rft.issue=4&rft.pages=729-737&rft.date=2007-04&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A7632947%23id-name%3DS2CID&rft_id=info%3Apmid%2F17408406&rft_id=info%3Adoi%2F10.1111%2Fj.1538-7836.2007.02427.x&rft.aulast=Lazo-Langner&rft.aufirst=A&rft.au=Goss%2C+GD&rft.au=Spaans%2C+JN&rft.au=Rodger%2C+MA&rft_id=https%3A%2F%2Fdoi.org%2F10.1111%252Fj.1538-7836.2007.02427.x&rfr_id=info%3Asid%2Fen.wikipedia.org%3AP-selectin" class="Z3988"></span></span> </li> <li id="cite_note-pmid21532885-29"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid21532885_29-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFBorsigVlodavskyIshai-MichaeliTorri2011" class="citation journal cs1">Borsig L, Vlodavsky I, Ishai-Michaeli R, Torri G, Vismara E (May 2011). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084621">"Sulfated hexasaccharides attenuate metastasis by inhibition of P-selectin and heparanase"</a>. <i>Neoplasia</i>. <b>13</b> (5): 445–452. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1593%2Fneo.101734">10.1593/neo.101734</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084621">3084621</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/21532885">21532885</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Neoplasia&rft.atitle=Sulfated+hexasaccharides+attenuate+metastasis+by+inhibition+of+P-selectin+and+heparanase&rft.volume=13&rft.issue=5&rft.pages=445-452&rft.date=2011-05&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3084621%23id-name%3DPMC&rft_id=info%3Apmid%2F21532885&rft_id=info%3Adoi%2F10.1593%2Fneo.101734&rft.aulast=Borsig&rft.aufirst=L&rft.au=Vlodavsky%2C+I&rft.au=Ishai-Michaeli%2C+R&rft.au=Torri%2C+G&rft.au=Vismara%2C+E&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC3084621&rfr_id=info%3Asid%2Fen.wikipedia.org%3AP-selectin" class="Z3988"></span></span> </li> <li id="cite_note-NEJM001-30"><span class="mw-cite-backlink"><b><a href="#cite_ref-NEJM001_30-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFAtagaKutlarKanterLiles2017" class="citation journal cs1">Ataga KI, Kutlar A, Kanter J, Liles D, Cancado R, Friedrisch J, et al. (February 2017). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481200">"Crizanlizumab for the Prevention of Pain Crises in Sickle Cell Disease"</a>. <i>The New England Journal of Medicine</i>. <b>376</b> (5): 429–439. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1056%2FNEJMoa1611770">10.1056/NEJMoa1611770</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481200">5481200</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/27959701">27959701</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=The+New+England+Journal+of+Medicine&rft.atitle=Crizanlizumab+for+the+Prevention+of+Pain+Crises+in+Sickle+Cell+Disease&rft.volume=376&rft.issue=5&rft.pages=429-439&rft.date=2017-02&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC5481200%23id-name%3DPMC&rft_id=info%3Apmid%2F27959701&rft_id=info%3Adoi%2F10.1056%2FNEJMoa1611770&rft.aulast=Ataga&rft.aufirst=KI&rft.au=Kutlar%2C+A&rft.au=Kanter%2C+J&rft.au=Liles%2C+D&rft.au=Cancado%2C+R&rft.au=Friedrisch%2C+J&rft.au=Guthrie%2C+TH&rft.au=Knight-Madden%2C+J&rft.au=Alvarez%2C+OA&rft.au=Gordeuk%2C+VR&rft.au=Gualandro%2C+S&rft.au=Colella%2C+MP&rft.au=Smith%2C+WR&rft.au=Rollins%2C+SA&rft.au=Stocker%2C+JW&rft.au=Rother%2C+RP&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC5481200&rfr_id=info%3Asid%2Fen.wikipedia.org%3AP-selectin" class="Z3988"></span></span> </li> </ol></div> <div class="mw-heading mw-heading2"><h2 id="Further_reading">Further reading</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=P-selectin&action=edit&section=9" title="Edit section: Further reading"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1239549316">.mw-parser-output .refbegin{margin-bottom:0.5em}.mw-parser-output .refbegin-hanging-indents>ul{margin-left:0}.mw-parser-output .refbegin-hanging-indents>ul>li{margin-left:0;padding-left:3.2em;text-indent:-3.2em}.mw-parser-output .refbegin-hanging-indents ul,.mw-parser-output .refbegin-hanging-indents ul li{list-style:none}@media(max-width:720px){.mw-parser-output .refbegin-hanging-indents>ul>li{padding-left:1.6em;text-indent:-1.6em}}.mw-parser-output .refbegin-columns{margin-top:0.3em}.mw-parser-output .refbegin-columns ul{margin-top:0}.mw-parser-output .refbegin-columns li{page-break-inside:avoid;break-inside:avoid-column}@media screen{.mw-parser-output .refbegin{font-size:90%}}</style><div class="refbegin refbegin-columns references-column-width" style="column-width: 35em"> <ul><li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFBajorathStenkampAruffo1993" class="citation journal cs1">Bajorath J, Stenkamp R, Aruffo A (November 1993). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2142283">"Knowledge-based model building of proteins: concepts and examples"</a>. <i>Protein Science</i>. <b>2</b> (11): 1798–1810. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1002%2Fpro.5560021103">10.1002/pro.5560021103</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2142283">2142283</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/7505680">7505680</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Protein+Science&rft.atitle=Knowledge-based+model+building+of+proteins%3A+concepts+and+examples&rft.volume=2&rft.issue=11&rft.pages=1798-1810&rft.date=1993-11&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2142283%23id-name%3DPMC&rft_id=info%3Apmid%2F7505680&rft_id=info%3Adoi%2F10.1002%2Fpro.5560021103&rft.aulast=Bajorath&rft.aufirst=J&rft.au=Stenkamp%2C+R&rft.au=Aruffo%2C+A&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2142283&rfr_id=info%3Asid%2Fen.wikipedia.org%3AP-selectin" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFVarkiVarki2002" class="citation journal cs1">Varki NM, Varki A (February 2002). "Heparin inhibition of selectin-mediated interactions during the hematogenous phase of carcinoma metastasis: rationale for clinical studies in humans". <i>Seminars in Thrombosis and Hemostasis</i>. <b>28</b> (1): 53–66. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1055%2Fs-2002-20564">10.1055/s-2002-20564</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/11885026">11885026</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:3222756">3222756</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Seminars+in+Thrombosis+and+Hemostasis&rft.atitle=Heparin+inhibition+of+selectin-mediated+interactions+during+the+hematogenous+phase+of+carcinoma+metastasis%3A+rationale+for+clinical+studies+in+humans&rft.volume=28&rft.issue=1&rft.pages=53-66&rft.date=2002-02&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A3222756%23id-name%3DS2CID&rft_id=info%3Apmid%2F11885026&rft_id=info%3Adoi%2F10.1055%2Fs-2002-20564&rft.aulast=Varki&rft.aufirst=NM&rft.au=Varki%2C+A&rfr_id=info%3Asid%2Fen.wikipedia.org%3AP-selectin" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFFurieFurie2004" class="citation journal cs1">Furie B, Furie BC (April 2004). "Role of platelet P-selectin and microparticle PSGL-1 in thrombus formation". <i>Trends in Molecular Medicine</i>. <b>10</b> (4): 171–178. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1016%2Fj.molmed.2004.02.008">10.1016/j.molmed.2004.02.008</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/15059608">15059608</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Trends+in+Molecular+Medicine&rft.atitle=Role+of+platelet+P-selectin+and+microparticle+PSGL-1+in+thrombus+formation&rft.volume=10&rft.issue=4&rft.pages=171-178&rft.date=2004-04&rft_id=info%3Adoi%2F10.1016%2Fj.molmed.2004.02.008&rft_id=info%3Apmid%2F15059608&rft.aulast=Furie&rft.aufirst=B&rft.au=Furie%2C+BC&rfr_id=info%3Asid%2Fen.wikipedia.org%3AP-selectin" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFCambienWagner2004" class="citation journal cs1">Cambien B, Wagner DD (April 2004). "A new role in hemostasis for the adhesion receptor P-selectin". <i>Trends in Molecular Medicine</i>. <b>10</b> (4): 179–186. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1016%2Fj.molmed.2004.02.007">10.1016/j.molmed.2004.02.007</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/15059609">15059609</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Trends+in+Molecular+Medicine&rft.atitle=A+new+role+in+hemostasis+for+the+adhesion+receptor+P-selectin&rft.volume=10&rft.issue=4&rft.pages=179-186&rft.date=2004-04&rft_id=info%3Adoi%2F10.1016%2Fj.molmed.2004.02.007&rft_id=info%3Apmid%2F15059609&rft.aulast=Cambien&rft.aufirst=B&rft.au=Wagner%2C+DD&rfr_id=info%3Asid%2Fen.wikipedia.org%3AP-selectin" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFChenGeng2006" class="citation journal cs1">Chen M, Geng JG (2006). "P-selectin mediates adhesion of leukocytes, platelets, and cancer cells in inflammation, thrombosis, and cancer growth and metastasis". <i>Archivum Immunologiae et Therapiae Experimentalis</i>. <b>54</b> (2): 75–84. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1007%2Fs00005-006-0010-6">10.1007/s00005-006-0010-6</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/16648968">16648968</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:33274938">33274938</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Archivum+Immunologiae+et+Therapiae+Experimentalis&rft.atitle=P-selectin+mediates+adhesion+of+leukocytes%2C+platelets%2C+and+cancer+cells+in+inflammation%2C+thrombosis%2C+and+cancer+growth+and+metastasis&rft.volume=54&rft.issue=2&rft.pages=75-84&rft.date=2006&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A33274938%23id-name%3DS2CID&rft_id=info%3Apmid%2F16648968&rft_id=info%3Adoi%2F10.1007%2Fs00005-006-0010-6&rft.aulast=Chen&rft.aufirst=M&rft.au=Geng%2C+JG&rfr_id=info%3Asid%2Fen.wikipedia.org%3AP-selectin" class="Z3988"></span></li></ul> </div> <div class="mw-heading mw-heading2"><h2 id="External_links">External links</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=P-selectin&action=edit&section=10" title="Edit section: External links"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a rel="nofollow" class="external text" href="https://meshb.nlm.nih.gov/record/ui?name=P-Selectin">P-Selectin</a> at the U.S. National Library of Medicine <a href="/wiki/Medical_Subject_Headings" title="Medical Subject Headings">Medical Subject Headings</a> (MeSH)</li> <li>Overview of all the structural information available in the <a href="/wiki/Protein_Data_Bank" title="Protein Data Bank">PDB</a> for <a href="/wiki/UniProt" title="UniProt">UniProt</a>: <i><a rel="nofollow" class="external text" href="https://www.ebi.ac.uk/pdbe/pdbe-kb/proteins/P16109">P16109</a></i> (Human P-selectin) at the <a href="/wiki/PDBe-KB" title="PDBe-KB">PDBe-KB</a>.</li> <li>Overview of all the structural information available in the <a href="/wiki/Protein_Data_Bank" title="Protein Data Bank">PDB</a> for <a href="/wiki/UniProt" title="UniProt">UniProt</a>: <i><a rel="nofollow" class="external text" href="https://www.ebi.ac.uk/pdbe/pdbe-kb/proteins/Q01102">Q01102</a></i> (Mouse P-selectin) at the <a href="/wiki/PDBe-KB" title="PDBe-KB">PDBe-KB</a>.</li></ul> <div class="navbox-styles"><style data-mw-deduplicate="TemplateStyles:r1129693374">.mw-parser-output .hlist dl,.mw-parser-output .hlist ol,.mw-parser-output .hlist ul{margin:0;padding:0}.mw-parser-output .hlist dd,.mw-parser-output .hlist dt,.mw-parser-output .hlist li{margin:0;display:inline}.mw-parser-output .hlist.inline,.mw-parser-output .hlist.inline dl,.mw-parser-output .hlist.inline ol,.mw-parser-output .hlist.inline ul,.mw-parser-output .hlist dl dl,.mw-parser-output .hlist dl ol,.mw-parser-output .hlist dl ul,.mw-parser-output .hlist ol dl,.mw-parser-output .hlist ol ol,.mw-parser-output .hlist ol ul,.mw-parser-output .hlist ul dl,.mw-parser-output .hlist ul ol,.mw-parser-output .hlist ul ul{display:inline}.mw-parser-output .hlist .mw-empty-li{display:none}.mw-parser-output .hlist dt::after{content:": "}.mw-parser-output .hlist dd::after,.mw-parser-output .hlist li::after{content:" · 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mw-gallery-traditional nochecker" style="line-height:130%"> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1fsb_EBI.jpg" class="mw-file-description" title="1fsb: STRUCTURE OF THE EGF DOMAIN OF P-SELECTIN, NMR, 19 STRUCTURES"><img alt="1fsb: STRUCTURE OF THE EGF DOMAIN OF P-SELECTIN, NMR, 19 STRUCTURES" src="//upload.wikimedia.org/wikipedia/commons/thumb/e/ee/PDB_1fsb_EBI.jpg/180px-PDB_1fsb_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/e/ee/PDB_1fsb_EBI.jpg/270px-PDB_1fsb_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/e/ee/PDB_1fsb_EBI.jpg/360px-PDB_1fsb_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1fsb</b>: STRUCTURE OF THE EGF DOMAIN OF P-SELECTIN, NMR, 19 STRUCTURES</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1g1q_EBI.jpg" class="mw-file-description" title="1g1q: Crystal structure of P-selectin lectin/EGF domains"><img alt="1g1q: Crystal structure of P-selectin lectin/EGF domains" src="//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/PDB_1g1q_EBI.jpg/180px-PDB_1g1q_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/PDB_1g1q_EBI.jpg/270px-PDB_1g1q_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/f/fb/PDB_1g1q_EBI.jpg/360px-PDB_1g1q_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1g1q</b>: Crystal structure of P-selectin lectin/EGF domains</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1g1r_EBI.jpg" class="mw-file-description" title="1g1r: Crystal structure of P-selectin lectin/EGF domains complexed with SLeX"><img alt="1g1r: Crystal structure of P-selectin lectin/EGF domains complexed with SLeX" src="//upload.wikimedia.org/wikipedia/commons/thumb/e/e3/PDB_1g1r_EBI.jpg/180px-PDB_1g1r_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/e/e3/PDB_1g1r_EBI.jpg/270px-PDB_1g1r_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/e/e3/PDB_1g1r_EBI.jpg/360px-PDB_1g1r_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1g1r</b>: Crystal structure of P-selectin lectin/EGF domains complexed with SLeX</div> </li> <li class="gallerybox" style="width: 215px"> <div class="thumb" style="width: 210px; height: 210px;"><span typeof="mw:File"><a href="/wiki/File:PDB_1g1s_EBI.jpg" class="mw-file-description" title="1g1s: P-SELECTIN LECTIN/EGF DOMAINS COMPLEXED WITH PSGL-1 PEPTIDE"><img alt="1g1s: P-SELECTIN LECTIN/EGF DOMAINS COMPLEXED WITH PSGL-1 PEPTIDE" src="//upload.wikimedia.org/wikipedia/commons/thumb/2/25/PDB_1g1s_EBI.jpg/180px-PDB_1g1s_EBI.jpg" decoding="async" width="180" height="135" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/2/25/PDB_1g1s_EBI.jpg/270px-PDB_1g1s_EBI.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/2/25/PDB_1g1s_EBI.jpg/360px-PDB_1g1s_EBI.jpg 2x" data-file-width="800" data-file-height="600" /></a></span></div> <div class="gallerytext"><b>1g1s</b>: P-SELECTIN LECTIN/EGF DOMAINS COMPLEXED WITH PSGL-1 PEPTIDE</div> </li> </ul></div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236075235"></div><div role="navigation" class="navbox" aria-labelledby="Proteins:_clusters_of_differentiation_(see_also_list_of_human_clusters_of_differentiation)" style="padding:3px"><table class="nowraplinks mw-collapsible mw-collapsed navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2" style="background:#e7dcc3"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1239400231"><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:Clusters_of_differentiation" title="Template:Clusters of differentiation"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Clusters_of_differentiation" title="Template talk:Clusters of differentiation"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Clusters_of_differentiation" title="Special:EditPage/Template:Clusters of differentiation"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Proteins:_clusters_of_differentiation_(see_also_list_of_human_clusters_of_differentiation)" style="font-size:114%;margin:0 4em"><a href="/wiki/Protein" title="Protein">Proteins</a>: <a href="/wiki/Cluster_of_differentiation" title="Cluster of differentiation">clusters of differentiation</a> (see also <a href="/wiki/List_of_human_clusters_of_differentiation" title="List of human clusters of differentiation">list of human clusters of differentiation</a>)</div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">1–50</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/CD1" title="CD1">CD1</a> <ul><li><a href="/wiki/Group_1_CD1" class="mw-redirect" title="Group 1 CD1">a-c</a></li> <li><a href="/wiki/CD1A" title="CD1A">1A</a></li> <li><a href="/wiki/CD1b" title="CD1b">1B</a></li> <li><a href="/wiki/CD1D" title="CD1D">1D</a></li> <li><a href="/wiki/CD1E" title="CD1E">1E</a></li></ul></li> <li><a href="/wiki/CD2" title="CD2">CD2</a></li> <li><a href="/wiki/CD3_(immunology)" title="CD3 (immunology)">CD3</a> <ul><li><a href="/wiki/CD3G" title="CD3G">γ</a></li> <li><a href="/wiki/CD3D" title="CD3D">δ</a></li> <li><a href="/wiki/CD3E" class="mw-redirect" title="CD3E">ε</a></li></ul></li> <li><a href="/wiki/CD4" title="CD4">CD4</a></li> <li><a href="/wiki/CD5_(protein)" title="CD5 (protein)">CD5</a></li> <li><a href="/wiki/CD6" title="CD6">CD6</a></li> <li><a href="/wiki/CD7" title="CD7">CD7</a></li> <li><a href="/wiki/CD8" title="CD8">CD8</a> <ul><li><a href="/wiki/CD8A" title="CD8A">a</a></li></ul></li> <li><a href="/wiki/CD9" title="CD9">CD9</a></li> <li><a href="/wiki/Neprilysin" title="Neprilysin">CD10</a></li> <li><i>CD11</i> <ul><li><a href="/wiki/CD11a" class="mw-redirect" title="CD11a">a</a></li> <li><a href="/wiki/Integrin_alpha_M" title="Integrin alpha M">b</a></li> <li><a href="/wiki/CD11c" class="mw-redirect" title="CD11c">c</a></li> <li><a href="/wiki/ITGAD" class="mw-redirect" title="ITGAD">d</a></li></ul></li> <li><a href="/wiki/Alanine_aminopeptidase" title="Alanine aminopeptidase">CD13</a></li> <li><a href="/wiki/CD14" title="CD14">CD14</a></li> <li><a href="/wiki/CD15" class="mw-redirect" title="CD15">CD15</a></li> <li><a href="/wiki/CD16" title="CD16">CD16</a> <ul><li><a href="/wiki/FCGR3A" title="FCGR3A">A</a></li> <li><a href="/wiki/FCGR3B" title="FCGR3B">B</a></li></ul></li> <li><a href="/wiki/CD18" class="mw-redirect" title="CD18">CD18</a></li> <li><a href="/wiki/CD19" title="CD19">CD19</a></li> <li><a href="/wiki/CD20" title="CD20">CD20</a></li> <li><a href="/wiki/Complement_receptor_2" title="Complement receptor 2">CD21</a></li> <li><a href="/wiki/CD22" title="CD22">CD22</a></li> <li><a href="/wiki/CD23" title="CD23">CD23</a></li> <li><a href="/wiki/CD24" title="CD24">CD24</a></li> <li><a href="/wiki/IL2RA" title="IL2RA">CD25</a></li> <li><a href="/wiki/Dipeptidyl_peptidase-4" title="Dipeptidyl peptidase-4">CD26</a></li> <li><a href="/wiki/CD27" title="CD27">CD27</a></li> <li><a href="/wiki/CD28" title="CD28">CD28</a></li> <li><a href="/wiki/Integrin_beta_1" title="Integrin beta 1">CD29</a></li> <li><a href="/wiki/CD30" title="CD30">CD30</a></li> <li><a href="/wiki/CD31" title="CD31">CD31</a></li> <li><a href="/wiki/CD32" title="CD32">CD32</a> <ul><li><a href="/wiki/FCGR2A" title="FCGR2A">A</a></li> <li><a href="/wiki/FCGR2B" title="FCGR2B">B</a></li></ul></li> <li><a href="/wiki/CD33" title="CD33">CD33</a></li> <li><a href="/wiki/CD34" title="CD34">CD34</a></li> <li><a href="/wiki/Complement_receptor_1" title="Complement receptor 1">CD35</a></li> <li><a href="/wiki/CD36" title="CD36">CD36</a></li> <li><a href="/wiki/CD37" title="CD37">CD37</a></li> <li><a href="/wiki/CD38" title="CD38">CD38</a></li> <li><a href="/wiki/ENTPD1" title="ENTPD1">CD39</a></li> <li><a href="/wiki/CD40_(protein)" title="CD40 (protein)">CD40</a></li> <li><a href="/wiki/ITGA2B" class="mw-redirect" title="ITGA2B">CD41</a></li> <li><a href="/wiki/Glycoprotein_Ib" title="Glycoprotein Ib">CD42</a> <ul><li><a href="/wiki/Glycoprotein_IX" title="Glycoprotein IX">a</a></li> <li><a href="/wiki/GP1BA" title="GP1BA">b</a></li> <li><a href="/wiki/GP1BB" title="GP1BB">c</a></li> <li><a href="/wiki/GP5_(gene)" title="GP5 (gene)">d</a></li></ul></li> <li><a href="/wiki/CD43" title="CD43">CD43</a></li> <li><a href="/wiki/CD44" title="CD44">CD44</a></li> <li><a href="/wiki/PTPRC" title="PTPRC">CD45</a></li> <li><a href="/wiki/CD46" title="CD46">CD46</a></li> <li><a href="/wiki/CD47" title="CD47">CD47</a></li> <li><a href="/wiki/CD48" title="CD48">CD48</a></li> <li><i>CD49</i> <ul><li><a href="/wiki/CD49a" class="mw-redirect" title="CD49a">a</a></li> <li><a href="/wiki/CD49b" class="mw-redirect" title="CD49b">b</a></li> <li><a href="/wiki/CD49c" class="mw-redirect" title="CD49c">c</a></li> <li><a href="/wiki/CD49d" class="mw-redirect" title="CD49d">d</a></li> <li><a href="/wiki/ITGA5" class="mw-redirect" title="ITGA5">e</a></li> <li><a href="/wiki/ITGA6" class="mw-redirect" title="ITGA6">f</a></li></ul></li> <li><a href="/wiki/ICAM3" title="ICAM3">CD50</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">51–100</th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/ITGAV" class="mw-redirect" title="ITGAV">CD51</a></li> <li><a href="/wiki/CD52" title="CD52">CD52</a></li> <li><a href="/wiki/CD53" title="CD53">CD53</a></li> <li><a href="/wiki/ICAM-1" title="ICAM-1">CD54</a></li> <li><a href="/wiki/Decay-accelerating_factor" title="Decay-accelerating factor">CD55</a></li> <li><a href="/wiki/Neural_cell_adhesion_molecule" title="Neural cell adhesion molecule">CD56</a></li> <li><a href="/wiki/B3GAT1" title="B3GAT1">CD57</a></li> <li><a href="/wiki/CD58" title="CD58">CD58</a></li> <li><a href="/wiki/CD59" title="CD59">CD59</a></li> <li><a href="/wiki/CD61" class="mw-redirect" title="CD61">CD61</a></li> <li><a href="/wiki/Selectin" title="Selectin">CD62</a> <ul><li><a href="/wiki/E-selectin" title="E-selectin">E</a></li> <li><a href="/wiki/L-selectin" title="L-selectin">L</a></li> <li><a class="mw-selflink selflink">P</a></li></ul></li> <li><a href="/wiki/CD63" title="CD63">CD63</a></li> <li><a href="/wiki/CD64_(biology)" title="CD64 (biology)">CD64</a> <ul><li><a href="/wiki/FCGR1A" title="FCGR1A">A</a></li> <li><a href="/wiki/FCGR1B" class="mw-redirect" title="FCGR1B">B</a></li> <li><a href="/wiki/FCGR1C" class="mw-redirect" title="FCGR1C">C</a></li></ul></li> <li><a href="/wiki/Carcinoembryonic_antigen" title="Carcinoembryonic antigen">CD66</a> <ul><li><a href="/wiki/CEACAM1" title="CEACAM1">a</a></li> <li><a href="/wiki/CEACAM8" title="CEACAM8">b</a></li> <li><a href="/wiki/CEACAM6" title="CEACAM6">c</a></li> <li><a href="/wiki/CEACAM3" title="CEACAM3">d</a></li> <li><a href="/wiki/CEACAM5" title="CEACAM5">e</a></li> <li><a href="/wiki/PSG1_(gene)" class="mw-redirect" title="PSG1 (gene)">f</a></li></ul></li> <li><a href="/wiki/CD68" title="CD68">CD68</a></li> <li><a href="/wiki/CD69" title="CD69">CD69</a></li> <li><a href="/wiki/CD70" title="CD70">CD70</a></li> <li><a href="/wiki/TFRC" class="mw-redirect" title="TFRC">CD71</a></li> <li><a href="/wiki/CD72" title="CD72">CD72</a></li> <li><a href="/wiki/NT5E" title="NT5E">CD73</a></li> <li><a href="/wiki/CD74" title="CD74">CD74</a></li> <li><a href="/wiki/CD78" title="CD78">CD78</a></li> <li><a href="/wiki/CD79" title="CD79">CD79</a> <ul><li><a href="/wiki/CD79A" title="CD79A">a</a></li> <li><a href="/wiki/CD79B" title="CD79B">b</a></li></ul></li> <li><a href="/wiki/CD80" title="CD80">CD80</a></li> <li><a href="/wiki/CD81" title="CD81">CD81</a></li> <li><a href="/wiki/CD82_(gene)" title="CD82 (gene)">CD82</a></li> <li><a href="/wiki/CD83" title="CD83">CD83</a></li> <li><a href="/wiki/CD84" title="CD84">CD84</a></li> <li><i>CD85</i> <ul><li><a href="/wiki/LILRB3" title="LILRB3">a</a></li> <li><a href="/wiki/LILRB2" title="LILRB2">d</a></li> <li><a href="/wiki/LILRA3" title="LILRA3">e</a></li> <li><a href="/wiki/LILRA2" title="LILRA2">h</a></li> <li><a href="/wiki/LILRB1" title="LILRB1">j</a></li> <li><a href="/wiki/LILRB4" title="LILRB4">k</a></li></ul></li> <li><a href="/wiki/CD86" title="CD86">CD86</a></li> <li><a href="/wiki/Urokinase_receptor" title="Urokinase receptor">CD87</a></li> <li><a href="/wiki/C5a_receptor" title="C5a receptor">CD88</a></li> <li><a href="/wiki/FCAR" title="FCAR">CD89</a></li> <li><a href="/wiki/CD90" title="CD90">CD90</a></li> <li><a href="/wiki/LRP1" title="LRP1">CD91</a> - <a href="/wiki/SLC44A1" class="mw-redirect" title="SLC44A1">CD92</a></li> <li><a href="/wiki/CD93" title="CD93">CD93</a></li> <li><a href="/wiki/KLRD1" title="KLRD1">CD94</a></li> <li><a href="/wiki/Fas_receptor" title="Fas receptor">CD95</a></li> <li><a href="/wiki/CD96" title="CD96">CD96</a></li> <li><a href="/wiki/CD97" title="CD97">CD97</a></li> <li><a href="/wiki/CD98" title="CD98">CD98</a></li> <li><a href="/wiki/CD99" title="CD99">CD99</a></li> <li><a href="/wiki/SEMA4D" title="SEMA4D">CD100</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">101–150</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/IGSF2" title="IGSF2">CD101</a></li> <li><a href="/wiki/ICAM2" title="ICAM2">CD102</a></li> <li><a href="/wiki/ITGAE" title="ITGAE">CD103</a></li> <li><a href="/wiki/ITGB4" class="mw-redirect" title="ITGB4">CD104</a></li> <li><a href="/wiki/Endoglin" title="Endoglin">CD105</a></li> <li><a href="/wiki/VCAM-1" title="VCAM-1">CD106</a></li> <li><i>CD107</i> <ul><li><a href="/wiki/LAMP1" title="LAMP1">a</a></li> <li><a href="/wiki/LAMP2" title="LAMP2">b</a></li></ul></li> <li><a href="/wiki/SEMA7A" title="SEMA7A">CD108</a></li> <li><a href="/wiki/CD109" title="CD109">CD109</a></li> <li><a href="/wiki/Myeloproliferative_leukemia_virus_oncogene" class="mw-redirect" title="Myeloproliferative leukemia virus oncogene">CD110</a></li> <li><a href="/wiki/PVRL1" class="mw-redirect" title="PVRL1">CD111</a></li> <li><a href="/wiki/PVRL2" class="mw-redirect" title="PVRL2">CD112</a></li> <li><a href="/wiki/PVRL3" class="mw-redirect" title="PVRL3">CD113</a></li> <li><a href="/wiki/Granulocyte_colony-stimulating_factor_receptor" title="Granulocyte colony-stimulating factor receptor">CD114</a></li> <li><a href="/wiki/Colony_stimulating_factor_1_receptor" title="Colony stimulating factor 1 receptor">CD115</a></li> <li><a href="/wiki/Granulocyte_macrophage_colony-stimulating_factor_receptor" class="mw-redirect" title="Granulocyte macrophage colony-stimulating factor receptor">CD116</a></li> <li><a href="/wiki/KIT_(gene)" title="KIT (gene)">CD117</a></li> <li><a href="/wiki/Leukemia_inhibitory_factor_receptor" title="Leukemia inhibitory factor receptor">CD118</a></li> <li><a href="/wiki/Interferon_gamma_receptor_1" title="Interferon gamma receptor 1">CD119</a></li> <li><a href="/wiki/CD120" title="CD120">CD120</a> <ul><li><a href="/wiki/TNFRSF1A" class="mw-redirect" title="TNFRSF1A">a</a></li> <li><a href="/wiki/TNFRSF1B" class="mw-redirect" title="TNFRSF1B">b</a></li></ul></li> <li><i>CD121</i> <ul><li><a href="/wiki/Interleukin_1_receptor,_type_I" title="Interleukin 1 receptor, type I">a</a></li> <li><a href="/wiki/Interleukin_1_receptor,_type_II" title="Interleukin 1 receptor, type II">b</a></li></ul></li> <li><a href="/wiki/IL2RB" title="IL2RB">CD122</a></li> <li><a href="/wiki/IL3RA" title="IL3RA">CD123</a></li> <li><a href="/wiki/Interleukin-4_receptor" title="Interleukin-4 receptor">CD124</a></li> <li><a href="/wiki/Interleukin_5_receptor_alpha_subunit" title="Interleukin 5 receptor alpha subunit">CD125</a></li> <li><a href="/wiki/Interleukin-6_receptor" title="Interleukin-6 receptor">CD126</a></li> <li><a href="/wiki/Interleukin-7_receptor" title="Interleukin-7 receptor">CD127</a></li> <li><a href="/wiki/Interleukin-9_receptor" title="Interleukin-9 receptor">CD129</a></li> <li><a href="/wiki/Glycoprotein_130" title="Glycoprotein 130">CD130</a></li> <li><a href="/wiki/CSF2RB" title="CSF2RB">CD131</a></li> <li><a href="/wiki/Common_gamma_chain" title="Common gamma chain">CD132</a></li> <li><a href="/wiki/CD133" title="CD133">CD133</a></li> <li><a href="/wiki/CD134" title="CD134">CD134</a></li> <li><a href="/wiki/CD135" title="CD135">CD135</a></li> <li><a href="/wiki/MST1R" title="MST1R">CD136</a></li> <li><a href="/wiki/CD137" title="CD137">CD137</a></li> <li><a href="/wiki/Syndecan_1" title="Syndecan 1">CD138</a></li> <li><a href="/wiki/PDGFRB" title="PDGFRB">CD140b</a></li> <li><a href="/wiki/Thrombomodulin" title="Thrombomodulin">CD141</a></li> <li><a href="/wiki/Tissue_factor" title="Tissue factor">CD142</a></li> <li><a href="/wiki/Angiotensin-converting_enzyme" title="Angiotensin-converting enzyme">CD143</a></li> <li><a href="/wiki/VE-cadherin" title="VE-cadherin">CD144</a></li> <li><a href="/wiki/CD146" title="CD146">CD146</a></li> <li><a href="/wiki/Basigin" title="Basigin">CD147</a></li> <li><a href="/wiki/PTPRJ" title="PTPRJ">CD148</a></li> <li><a href="/wiki/SLAMF1" title="SLAMF1">CD150</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">151–200</th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/CD151" title="CD151">CD151</a></li> <li><a href="/wiki/CTLA-4" class="mw-redirect" title="CTLA-4">CD152</a></li> <li><a href="/wiki/CD153" title="CD153">CD153</a></li> <li><a href="/wiki/CD154" title="CD154">CD154</a></li> <li><a href="/wiki/CD155" title="CD155">CD155</a></li> <li><i>CD156</i> <ul><li><a href="/wiki/ADAM8" title="ADAM8">a</a></li> <li><a href="/wiki/ADAM17" title="ADAM17">b</a></li> <li><a href="/wiki/ADAM10" title="ADAM10">c</a></li></ul></li> <li><a href="/wiki/BST1" title="BST1">CD157</a></li> <li><i>CD158</i> (<a href="/wiki/KIR2DL1" title="KIR2DL1">a</a></li> <li><a href="/wiki/KIR2DL4" title="KIR2DL4">d</a></li> <li><a href="/wiki/KIR3DL1" title="KIR3DL1">e</a></li> <li><a href="/wiki/KIR2DS4" title="KIR2DS4">i</a></li> <li><a href="/wiki/KIR3DL2" title="KIR3DL2">k</a>)</li> <li><i>CD159</i> <ul><li><a href="/wiki/NKG2" title="NKG2">a</a></li> <li><a href="/wiki/KLRC2" title="KLRC2">c</a></li></ul></li> <li><a href="/wiki/CD160" title="CD160">CD160</a></li> <li><a href="/wiki/KLRB1" title="KLRB1">CD161</a></li> <li><a href="/wiki/P-selectin_glycoprotein_ligand-1" title="P-selectin glycoprotein ligand-1">CD162</a></li> <li><a href="/wiki/CD163" title="CD163">CD163</a></li> <li><a href="/wiki/CD164" title="CD164">CD164</a></li> <li><a href="/wiki/ALCAM" title="ALCAM">CD166</a></li> <li><i>CD167</i> <ul><li><a href="/wiki/DDR1" title="DDR1">a</a></li> <li><a href="/wiki/Discoidin_domain-containing_receptor_2" title="Discoidin domain-containing receptor 2">b</a></li></ul></li> <li><a href="/wiki/Hyaluronan-mediated_motility_receptor" title="Hyaluronan-mediated motility receptor">CD168</a></li> <li><a href="/wiki/Sialoadhesin" title="Sialoadhesin">CD169</a></li> <li><a href="/wiki/SIGLEC5" title="SIGLEC5">CD170</a></li> <li><a href="/wiki/L1_(protein)" title="L1 (protein)">CD171</a></li> <li><i>CD172</i> <ul><li><a href="/wiki/Signal-regulatory_protein_alpha" title="Signal-regulatory protein alpha">a</a></li> <li><a href="/wiki/SIRPB1" title="SIRPB1">b</a></li> <li><a href="/wiki/SIRPG" title="SIRPG">g</a></li></ul></li> <li><a href="/wiki/Fucosyltransferase_3" title="Fucosyltransferase 3">CD174</a></li> <li><a href="/wiki/CD177" title="CD177">CD177</a></li> <li><a href="/wiki/Fas_ligand" title="Fas ligand">CD178</a></li> <li><i>CD179</i> <ul><li><a href="/wiki/VPREB1" title="VPREB1">a</a></li> <li><a href="/wiki/IGLL1" title="IGLL1">b</a></li></ul></li> <li><a href="/wiki/CD180" title="CD180">CD180</a></li> <li><a href="/wiki/Interleukin_8_receptor,_alpha" title="Interleukin 8 receptor, alpha">CD181</a></li> <li><a href="/wiki/Interleukin_8_receptor,_beta" title="Interleukin 8 receptor, beta">CD182</a></li> <li><a href="/wiki/CXCR3" title="CXCR3">CD183</a></li> <li><a href="/wiki/CXCR4" title="CXCR4">CD184</a></li> <li><a href="/wiki/CXCR5" title="CXCR5">CD185</a></li> <li><a href="/wiki/CXCR6" title="CXCR6">CD186</a></li> <li><a href="/wiki/CCR1" title="CCR1">CD191</a></li> <li><a href="/wiki/CCR2" title="CCR2">CD192</a></li> <li><a href="/wiki/CCR3_(gene)" title="CCR3 (gene)">CD193</a></li> <li><a href="/wiki/CCR4" title="CCR4">CD194</a></li> <li><a href="/wiki/CCR5" title="CCR5">CD195</a></li> <li><a href="/wiki/C-C_chemokine_receptor_type_6" title="C-C chemokine receptor type 6">CD196</a></li> <li><a href="/wiki/C-C_chemokine_receptor_type_7" title="C-C chemokine receptor type 7">CD197</a></li> <li><a href="/wiki/CCR8_(gene)" title="CCR8 (gene)">CDw198</a></li> <li><a href="/wiki/CCR9" title="CCR9">CDw199</a></li> <li><a href="/wiki/CD200" title="CD200">CD200</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">201–250</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Endothelial_protein_C_receptor" title="Endothelial protein C receptor">CD201</a></li> <li><a href="/wiki/TEK_tyrosine_kinase" title="TEK tyrosine kinase">CD202b</a></li> <li><a href="/wiki/MSR1" title="MSR1">CD204</a></li> <li><a href="/wiki/LY75" class="mw-redirect" title="LY75">CD205</a></li> <li><a href="/wiki/Mannose_receptor" title="Mannose receptor">CD206</a></li> <li><a href="/wiki/CD207" class="mw-redirect" title="CD207">CD207</a></li> <li><a href="/wiki/LAMP3" title="LAMP3">CD208</a></li> <li><a href="/wiki/DC-SIGN" title="DC-SIGN">CD209</a></li> <li><i>CDw210</i> <ul><li><a href="/wiki/Interleukin_10_receptor,_alpha_subunit" title="Interleukin 10 receptor, alpha subunit">a</a></li> <li><a href="/wiki/Interleukin_10_receptor,_beta_subunit" title="Interleukin 10 receptor, beta subunit">b</a></li></ul></li> <li><a href="/wiki/Interleukin_12_receptor,_beta_1_subunit" title="Interleukin 12 receptor, beta 1 subunit">CD212</a></li> <li><i>CD213a</i> <ul><li><a href="/wiki/IL13RA1" class="mw-redirect" title="IL13RA1">1</a></li> <li><a href="/wiki/IL13RA2" title="IL13RA2">2</a></li></ul></li> <li><a href="/wiki/IL17RA" title="IL17RA">CD217</a></li> <li><i>CD218</i> (<a href="/wiki/IL18R1" title="IL18R1">a</a></li> <li><a href="/wiki/IL18RAP" title="IL18RAP">b</a>)</li> <li><a href="/wiki/Insulin_receptor" title="Insulin receptor">CD220</a></li> <li><a href="/wiki/Insulin-like_growth_factor_1_receptor" title="Insulin-like growth factor 1 receptor">CD221</a></li> <li><a href="/wiki/Insulin-like_growth_factor_2_receptor" title="Insulin-like growth factor 2 receptor">CD222</a></li> <li><a href="/wiki/LAG3" class="mw-redirect" title="LAG3">CD223</a></li> <li><a href="/wiki/GGT1" class="mw-redirect" title="GGT1">CD224</a></li> <li><a href="/wiki/IFITM1" title="IFITM1">CD225</a></li> <li><a href="/wiki/CD226" title="CD226">CD226</a></li> <li><a href="/wiki/MUC1" class="mw-redirect" title="MUC1">CD227</a></li> <li><a href="/wiki/MFI2" class="mw-redirect" title="MFI2">CD228</a></li> <li><a href="/wiki/LY9" title="LY9">CD229</a></li> <li><a href="/wiki/PRNP" class="mw-redirect" title="PRNP">CD230</a></li> <li><a href="/wiki/Band_3" class="mw-redirect" title="Band 3">CD233</a></li> <li><a href="/wiki/Duffy_antigen_system" title="Duffy antigen system">CD234</a></li> <li><i>CD235</i> <ul><li><a href="/wiki/GYPA" class="mw-redirect" title="GYPA">a</a></li> <li><a href="/wiki/GYPB" title="GYPB">b</a></li></ul></li> <li><a href="/wiki/Glycophorin_C" title="Glycophorin C">CD236</a></li> <li><a href="/wiki/Kell_antigen_system" title="Kell antigen system">CD238</a></li> <li><a href="/wiki/Basal_cell_adhesion_molecule" title="Basal cell adhesion molecule">CD239</a></li> <li><a href="/wiki/RHCE_(gene)" title="RHCE (gene)">CD240CE</a></li> <li><a href="/wiki/RHD_(gene)" title="RHD (gene)">CD240D</a></li> <li><a href="/wiki/RHAG" title="RHAG">CD241</a></li> <li><a href="/wiki/P-glycoprotein" title="P-glycoprotein">CD243</a></li> <li><a href="/wiki/CD244" title="CD244">CD244</a></li> <li><a href="/wiki/Anaplastic_lymphoma_kinase" title="Anaplastic lymphoma kinase">CD246</a></li> <li><a href="/wiki/CD247" class="mw-redirect" title="CD247">CD247</a> - <a href="/wiki/CD248" title="CD248">CD248</a></li> <li><a href="/wiki/Glutamyl_aminopeptidase" title="Glutamyl aminopeptidase">CD249</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">251–300</th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/OX40L" class="mw-redirect" title="OX40L"> CD252</a></li> <li><a href="/wiki/TRAIL" title="TRAIL">CD253</a></li> <li><a href="/wiki/RANKL" title="RANKL">CD254</a></li> <li><a href="/wiki/TNFSF13" class="mw-redirect" title="TNFSF13">CD256</a></li> <li><a href="/wiki/B-cell_activating_factor" title="B-cell activating factor">CD257</a></li> <li><a href="/wiki/TNFSF14" class="mw-redirect" title="TNFSF14">CD258</a></li> <li><a href="/wiki/TNFRSF10A" class="mw-redirect" title="TNFRSF10A">CD261</a></li> <li><a href="/wiki/TNFRSF10B" class="mw-redirect" title="TNFRSF10B">CD262</a></li> <li><a href="/wiki/TNFRSF10C" class="mw-redirect" title="TNFRSF10C">CD263</a></li> <li><a href="/wiki/TNFRSF10D" class="mw-redirect" title="TNFRSF10D">CD264</a></li> <li><a href="/wiki/RANK" title="RANK">CD265</a></li> <li><a href="/wiki/TNFRSF12A" title="TNFRSF12A">CD266</a></li> <li><a href="/wiki/TNFRSF13B" class="mw-redirect" title="TNFRSF13B">CD267</a></li> <li><a href="/wiki/TNFRSF13C" class="mw-redirect" title="TNFRSF13C">CD268</a></li> <li><a href="/wiki/TNFRSF17" class="mw-redirect" title="TNFRSF17">CD269</a></li> <li><a href="/wiki/Low-affinity_nerve_growth_factor_receptor" title="Low-affinity nerve growth factor receptor">CD271</a></li> <li><a href="/wiki/BTLA" title="BTLA">CD272</a></li> <li><a href="/wiki/PDCD1LG2" title="PDCD1LG2">CD273</a></li> <li><a href="/wiki/CD274" class="mw-redirect" title="CD274">CD274</a></li> <li><a href="/wiki/ICOSLG" title="ICOSLG">CD275</a></li> <li><a href="/wiki/CD276" title="CD276">CD276</a></li> <li><a href="/wiki/CD278" title="CD278">CD278</a></li> <li><a href="/wiki/Programmed_cell_death_protein_1" title="Programmed cell death protein 1">CD279</a></li> <li><a href="/wiki/Mannose_receptor" title="Mannose receptor">CD280</a></li> <li><a href="/wiki/TLR_1" class="mw-redirect" title="TLR 1">CD281</a></li> <li><a href="/wiki/TLR2" class="mw-redirect" title="TLR2">CD282</a></li> <li><a href="/wiki/TLR3" class="mw-redirect" title="TLR3">CD283</a></li> <li><a href="/wiki/TLR4" class="mw-redirect" title="TLR4">CD284</a></li> <li><a href="/wiki/TLR6" class="mw-redirect" title="TLR6">CD286</a></li> <li><a href="/wiki/TLR8" class="mw-redirect" title="TLR8">CD288</a></li> <li><a href="/wiki/TLR9" class="mw-redirect" title="TLR9">CD289</a></li> <li><a href="/wiki/TLR10" class="mw-redirect" title="TLR10">CD290</a></li> <li><a href="/wiki/BMPR1A" title="BMPR1A">CD292</a></li> <li><a href="/wiki/BMPR1B" title="BMPR1B">CDw293</a></li> <li><a href="/wiki/CD294" class="mw-redirect" title="CD294">CD294</a></li> <li><a href="/wiki/Leptin_receptor" title="Leptin receptor">CD295</a></li> <li><a href="/wiki/ART4" title="ART4">CD297</a></li> <li><a href="/wiki/ATP1B3" title="ATP1B3">CD298</a></li> <li><a href="/wiki/CLEC4M" title="CLEC4M">CD299</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%;background-color: AntiqueWhite">301–350</th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/CD300A" title="CD300A">CD300A</a></li> <li><a href="/wiki/CLEC10A" title="CLEC10A">CD301</a></li> <li><a href="/wiki/CD302" title="CD302">CD302</a></li> <li><a href="/wiki/CLEC4C" title="CLEC4C">CD303</a></li> <li><a href="/wiki/Neuropilin" title="Neuropilin">CD304</a></li> <li><a href="/wiki/LAIR1" title="LAIR1">CD305</a></li> <li><a href="/wiki/LAIR2" title="LAIR2">CD306</a></li> <li><a href="/wiki/FCRL5" title="FCRL5">CD307</a></li> <li><a href="/wiki/Kinase_insert_domain_receptor" title="Kinase insert domain receptor">CD309</a></li> <li><a href="/wiki/EMR2" title="EMR2">CD312</a></li> <li><a href="/wiki/NKG2D" title="NKG2D">CD314</a></li> <li><a href="/wiki/PTGFRN" title="PTGFRN">CD315</a></li> <li><a href="/wiki/IGSF8" title="IGSF8">CD316</a></li> <li><a href="/wiki/Tetherin" title="Tetherin">CD317</a></li> <li><a href="/wiki/CDCP1" title="CDCP1">CD318</a></li> <li><a href="/wiki/CD320" title="CD320">CD320</a></li> <li><a href="/wiki/F11_receptor" title="F11 receptor">CD321</a></li> <li><a href="/wiki/JAM2" title="JAM2">CD322</a></li> <li><a href="/wiki/CDH1_(gene)" class="mw-redirect" title="CDH1 (gene)">CD324</a></li> <li><a href="/wiki/CDH2" class="mw-redirect" title="CDH2">CD325</a></li> <li><a href="/wiki/Epithelial_cell_adhesion_molecule" title="Epithelial cell adhesion molecule">CD326</a></li> <li><a href="/wiki/SIGLEC6" title="SIGLEC6">CD327</a></li> <li><a href="/wiki/SIGLEC7" title="SIGLEC7">CD328</a></li> <li><a href="/wiki/SIGLEC9" title="SIGLEC9">CD329</a></li> <li><a href="/wiki/Fibroblast_growth_factor_receptor_1" title="Fibroblast growth factor receptor 1">CD331</a></li> <li><a href="/wiki/Fibroblast_growth_factor_receptor_2" title="Fibroblast growth factor receptor 2">CD332</a></li> <li><a href="/wiki/Fibroblast_growth_factor_receptor_3" title="Fibroblast growth factor receptor 3">CD333</a></li> <li><a href="/wiki/Fibroblast_growth_factor_receptor_4" title="Fibroblast growth factor receptor 4">CD334</a></li> <li><a href="/wiki/NCR1" title="NCR1">CD335</a></li> <li><a href="/wiki/NCR2" title="NCR2">CD336</a></li> <li><a href="/wiki/NCR3" title="NCR3">CD337</a></li> <li><a href="/wiki/ABCG2" title="ABCG2">CD338</a></li> <li><a href="/wiki/JAG1" title="JAG1">CD339</a></li> <li><a href="/wiki/HER2/neu" class="mw-redirect" title="HER2/neu">CD340</a></li> <li><a href="/wiki/FZD4" class="mw-redirect" title="FZD4">CD344</a></li> <li><a href="/wiki/FZD9" class="mw-redirect" title="FZD9">CD349</a></li> <li><a href="/wiki/FZD10" class="mw-redirect" title="FZD10">CD350</a></li></ul> </div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236075235"></div><div role="navigation" class="navbox" aria-labelledby="Membrane_proteins:_cell_adhesion_molecules" style="padding:3px"><table class="nowraplinks hlist mw-collapsible autocollapse navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1239400231"><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-view"><a href="/wiki/Template:Cell_adhesion_molecules" title="Template:Cell adhesion molecules"><abbr title="View this template">v</abbr></a></li><li class="nv-talk"><a href="/wiki/Template_talk:Cell_adhesion_molecules" title="Template talk:Cell adhesion molecules"><abbr title="Discuss this template">t</abbr></a></li><li class="nv-edit"><a href="/wiki/Special:EditPage/Template:Cell_adhesion_molecules" title="Special:EditPage/Template:Cell adhesion molecules"><abbr title="Edit this template">e</abbr></a></li></ul></div><div id="Membrane_proteins:_cell_adhesion_molecules" style="font-size:114%;margin:0 4em"><a href="/wiki/Membrane_protein" title="Membrane protein">Membrane proteins</a>: <a href="/wiki/Cell_adhesion_molecule" title="Cell adhesion molecule">cell adhesion molecules</a></div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Cell_adhesion_molecule#Calcium-independent" title="Cell adhesion molecule">Calcium-independent</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/IgSF_CAM" title="IgSF CAM">IgSF CAM</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Neural_cell_adhesion_molecule" title="Neural cell adhesion molecule">N-CAM</a> (<a href="/wiki/Myelin_protein_zero" title="Myelin protein zero">Myelin protein zero</a>)</li> <li><a href="/wiki/Intercellular_adhesion_molecule" title="Intercellular adhesion molecule">ICAM</a> (<a href="/wiki/ICAM-1" title="ICAM-1">1</a>, <a href="/wiki/ICAM5" title="ICAM5">5</a>)</li> <li><a href="/wiki/VCAM-1" title="VCAM-1">VCAM-1</a></li> <li><a href="/wiki/CD31" title="CD31">PE-CAM</a></li> <li><a href="/wiki/L1_family" title="L1 family">L1 family</a> <ul><li><a href="/wiki/L1_(protein)" title="L1 (protein)">L1-CAM</a></li> <li><a href="/wiki/NRCAM" title="NRCAM">NRCAM</a></li> <li><a href="/wiki/NFASC" title="NFASC">NFASC</a></li> <li><a href="/wiki/CHL1" title="CHL1">CHL1</a></li></ul></li> <li><a href="/wiki/Nectin" title="Nectin">Nectin</a> <ul><li><a href="/wiki/PVRL1" class="mw-redirect" title="PVRL1">PVRL1</a></li> <li><a href="/wiki/PVRL2" class="mw-redirect" title="PVRL2">PVRL2</a></li> <li><a href="/wiki/PVRL3" class="mw-redirect" title="PVRL3">PVRL3</a></li> <li><a href="/wiki/CADM1" class="mw-redirect" title="CADM1">CADM1</a></li> <li><a href="/wiki/CADM3" title="CADM3">CADM3</a></li> <li><a href="/wiki/CD155" title="CD155">CD155</a></li></ul></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Integrin" title="Integrin">Integrins</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Lymphocyte_function-associated_antigen_1" title="Lymphocyte function-associated antigen 1">LFA-1</a> (<a href="/wiki/CD11a" class="mw-redirect" title="CD11a">CD11a</a>+<a href="/wiki/CD18" class="mw-redirect" title="CD18">CD18</a>)</li> <li><a href="/wiki/Integrin_alphaXbeta2" title="Integrin alphaXbeta2">Integrin alphaXbeta2</a> (<a href="/wiki/CD11c" class="mw-redirect" title="CD11c">CD11c</a>+<a href="/wiki/CD18" class="mw-redirect" title="CD18">CD18</a>)</li> <li><a href="/wiki/Macrophage-1_antigen" title="Macrophage-1 antigen">Macrophage-1 antigen</a> (<a href="/wiki/CD11b" class="mw-redirect" title="CD11b">CD11b</a>+<a href="/wiki/CD18" class="mw-redirect" title="CD18">CD18</a>)</li> <li><a href="/wiki/VLA-4" title="VLA-4">VLA-4</a> (<a href="/wiki/CD49d" class="mw-redirect" title="CD49d">CD49d</a>+<a href="/wiki/CD29" class="mw-redirect" title="CD29">CD29</a>)</li> <li><a href="/wiki/Glycoprotein_IIb/IIIa" title="Glycoprotein IIb/IIIa">Glycoprotein IIb/IIIa</a> (<a href="/wiki/ITGA2B" class="mw-redirect" title="ITGA2B">ITGA2B</a>+<a href="/wiki/ITGB3" class="mw-redirect" title="ITGB3">ITGB3</a>)</li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Cell_adhesion_molecule#Calcium-dependent" title="Cell adhesion molecule">Calcium-dependent</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Cadherin" title="Cadherin">Cadherins</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%">Classical</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/CDH1_(gene)" class="mw-redirect" title="CDH1 (gene)">CDH1</a></li> <li><a href="/wiki/CDH2" class="mw-redirect" title="CDH2">CDH2</a></li> <li><a href="/wiki/CDH3_(gene)" title="CDH3 (gene)">CDH3</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Desmosome" title="Desmosome">Desmosomal</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Desmoglein" title="Desmoglein">Desmoglein</a> (<a href="/wiki/Desmoglein-1" title="Desmoglein-1">DSG1</a>, <a href="/wiki/Desmoglein-2" title="Desmoglein-2">DSG2</a>, <a href="/wiki/Desmoglein-3" title="Desmoglein-3">DSG3</a>, <a href="/wiki/Desmoglein-4" title="Desmoglein-4">DSG4</a>)</li> <li><a href="/wiki/Desmocollin" title="Desmocollin">Desmocollin</a> (<a href="/wiki/DSC1" title="DSC1">DSC1</a>, <a href="/wiki/DSC2" title="DSC2">DSC2</a>, <a href="/wiki/DSC3" title="DSC3">DSC3</a>)</li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Protocadherin" title="Protocadherin">Protocadherin</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/PCDH1" title="PCDH1">PCDH1</a></li> <li><a href="/wiki/PCDH15" title="PCDH15">PCDH15</a></li> <li><a href="/wiki/Protocadherin_19" title="Protocadherin 19">PCDH19</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Unconventional/ungrouped</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/T-cadherin" title="T-cadherin">T-cadherin</a></li> <li><a href="/wiki/CDH4" title="CDH4">CDH4</a></li> <li><a href="/wiki/VE-cadherin" title="VE-cadherin">CDH5</a></li> <li><a href="/wiki/CDH6" title="CDH6">CDH6</a></li> <li><a href="/wiki/CDH8" title="CDH8">CDH8</a></li> <li><a href="/wiki/CDH11" title="CDH11">CDH11</a></li> <li><a href="/wiki/CDH12" title="CDH12">CDH12</a></li> <li><a href="/wiki/CDH15" title="CDH15">CDH15</a></li> <li><a href="/wiki/CDH16" title="CDH16">CDH16</a></li> <li><a href="/wiki/CDH17" title="CDH17">CDH17</a></li> <li><a href="/wiki/CDH9" title="CDH9">CDH9</a></li> <li><a href="/wiki/CDH10" title="CDH10">CDH10</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Selectin" title="Selectin">Selectins</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/E-selectin" title="E-selectin">E-selectin</a></li> <li><a href="/wiki/L-selectin" title="L-selectin">L-selectin</a></li> <li><a class="mw-selflink selflink">P-selectin</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Other</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Lymphocyte_homing_receptor" title="Lymphocyte homing receptor">Lymphocyte homing receptor</a>: <a href="/wiki/CD44" title="CD44">CD44</a></li> <li><a href="/wiki/L-selectin" title="L-selectin">L-selectin</a></li> <li><i><a href="/wiki/Integrin" title="Integrin">integrin</a></i> (<a href="/wiki/VLA-4" title="VLA-4">VLA-4</a>, <a href="/wiki/LFA-1" class="mw-redirect" title="LFA-1">LFA-1</a>)</li></ul> <ul><li><a href="/wiki/Carcinoembryonic_antigen" title="Carcinoembryonic antigen">Carcinoembryonic antigen</a></li> <li><a href="/wiki/CD24" title="CD24">CD24</a></li> <li><a href="/wiki/CD44" title="CD44">CD44</a></li> <li><a href="/wiki/CD146" title="CD146">CD146</a></li> <li><a href="/wiki/Epithelial_cell_adhesion_molecule" title="Epithelial cell adhesion molecule">EpCAM</a></li></ul> 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