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discovery dynamic! Transition from hit-to-lead with XD3, our revolutionary combination of <a href="https://www.x-chemrx.com/artemisai/"><strong style="color: #2aa1db;">ArtemisAI</strong></a>, DEL and medicinal chemistry. <a href="#HITMiner" class="scrollto"><strong style="color: #2aa1db;">HITMiner</strong></a> combines DEL + AI to get more hits, faster. <a href="#LEADChaser" class="scrollto"><strong style="color: #98d801;">LEADChaser</strong></a> leverages DEL + MedChem and enables you to avoid hand-offs and accelerate through hit-to-lead. <a href="#DRUGFinder" class="scrollto"><strong style="color: #ef4379;">DRUGFinder</strong></a> facilitates multiparameter optimization and speeds up medicinal chemistry through use of ArtemisAI’s predictive models. Unlock the power of your data and accelerate your drug discovery program with XD3.</p> </div> </div> <div id="ai-del-content" class="xd3-content"> <div class="xd3-content-inside"> <div class="xd3-close close"></div> <h2><svg viewBox="0 0 242.24 41.48" width="212" height="36"><title>HITMiner</title><path fill="#fff" d="M91.49 39.84V3.94c0-.7.38-1.08 1.08-1.08h3.88c.59 0 .97.16 1.29.7l15.42 24.69 15.42-24.69c.32-.54.7-.7 1.29-.7h3.83c.7 0 1.08.38 1.08 1.08v35.9c0 .7-.38 1.08-1.08 1.08h-3.13c-.7 0-1.08-.38-1.08-1.08V11.59l-13.96 21.94c-.32.54-.75.7-1.29.7h-2.21c-.59 0-.97-.16-1.29-.7l-13.96-22v28.3c0 .7-.38 1.08-1.08 1.08h-3.13c-.7 0-1.08-.38-1.08-1.08ZM141.24 6.2V1.08c0-.7.38-1.08 1.08-1.08h2.91c.7 0 1.08.38 1.08 1.08V6.2c0 .7-.38 1.08-1.08 1.08h-2.91c-.7 0-1.08-.38-1.08-1.08Zm0 33.64V11.7c0-.7.38-1.08 1.08-1.08h2.91c.7 0 1.08.38 1.08 1.08v28.14c0 .7-.38 1.08-1.08 1.08h-2.91c-.7 0-1.08-.38-1.08-1.08Zm41.34-17.25V39.9c0 .7-.38 1.08-1.08 1.08h-2.91c-.7 0-1.08-.38-1.08-1.08V22.16c0-5.55-1.19-6.74-6.15-6.74h-7.66c-4.26 0-6.2.97-6.2 6.74v17.68c0 .7-.38 1.08-1.08 1.08h-2.91c-.7 0-1.08-.38-1.08-1.08V11.7c0-.7.38-1.08 1.08-1.08h2.91c.7 0 1.08.38 1.08 1.08v2.86c1.19-2.64 3.67-3.94 8.57-3.94h5.34c9 0 11.16 3.94 11.16 11.97Zm5.11 6.36v-6.52c0-7.82 2.16-11.81 11.16-11.81h7.6c9 0 11.16 3.99 11.16 11.81v4.85c0 .7-.38 1.08-1.08 1.08h-23.77v1.02c0 5.55 1.19 6.74 6.2 6.74h15.15c.7 0 1.08.38 1.08 1.08v2.64c0 .7-.38 1.08-1.08 1.08h-15.26c-9 0-11.16-3.94-11.16-11.97Zm24.85-5.18v-1.73c0-5.44-1.19-6.63-6.2-6.63h-7.39c-5.01 0-6.2 1.19-6.2 6.63v1.73h19.79Zm28.62-13.15c.7 0 1.08.38 1.08 1.08v2.64c0 .7-.38 1.08-1.08 1.08h-7.33c-4.26 0-6.2.97-6.2 6.74v17.68c0 .7-.38 1.08-1.08 1.08h-2.91c-.7 0-1.08-.38-1.08-1.08V11.7c0-.7.38-1.08 1.08-1.08h2.91c.7 0 1.08.38 1.08 1.08v2.86c1.19-2.64 3.67-3.94 8.57-3.94h4.96Z"/><path fill="#15aee5" d="M52.16 4.92v33.63c0 1.62-1.31 2.93-2.93 2.93s-2.93-1.31-2.93-2.93V4.92c0-1.62 1.31-2.93 2.93-2.93s2.93 1.31 2.93 2.93Zm31.41-2.65H58.81c-1.62 0-2.93 1.31-2.93 2.93s1.31 2.93 2.93 2.93h9.45v30.42c0 1.62 1.31 2.93 2.93 2.93s2.93-1.31 2.93-2.93V8.13h9.45c1.62 0 2.93-1.31 2.93-2.93s-1.31-2.93-2.93-2.93Zm-47.5-.08c-1.6 0-2.89 1.29-2.89 2.89v13.69H5.78V5.08c0-1.6-1.29-2.89-2.89-2.89S0 3.48 0 5.08v33.15c0 1.6 1.29 2.89 2.89 2.89s2.89-1.29 2.89-2.89V24.54h27.39v13.69c0 1.6 1.29 2.89 2.89 2.89s2.89-1.29 2.89-2.89V5.08c0-1.6-1.29-2.89-2.89-2.89Z"/></svg></h2> <p><a href="#HITMiner" class="scrollto">HITMiner</a> applies <a href="https://www.x-chemrx.com/artemisai/"><strong>ArtemisAI’s</strong></a> leading AI platform to the depth of DEL screening data, to predict new binders and expand the scope of chemical space accessed for hit generation. Having multiple starting points provides more information and increases the probability of finding clinical candidates faster. <a href="#HITMiner" class="scrollto">HITMiner</a> maximizes the scope of hit generation, supplying you with the maximum number of shots on goal. Accelerate your drug discovery program by getting more hits, faster, with <a href="#HITMiner" class="scrollto">HITMiner</a>.</p> <p style="text-align:center;margin:0;"><a href="#HITMiner" class="btn reverse scrollto">Learn More</a></p> </div> </div> <div id="del-medchem-content" class="xd3-content"> <div class="xd3-content-inside"> <div class="xd3-close close"></div> <h2><svg viewBox="0 0 374.69 41.79" width="265" height="36"><title>LEADChaser</title><path fill="#fff" d="M174.71 27.99V16.11c0-8.46 3.53-13.23 12.85-13.23h12.09c9.33 0 12.85 4.77 12.85 13.23v.43c0 .71-.38 1.08-1.08 1.08h-3.15c-.71 0-1.08-.33-1.08-.87v-.81c0-6.18-2.06-7.92-7.54-7.92h-12.09c-5.48 0-7.54 1.74-7.54 7.92v12.2c0 6.13 2.12 7.86 7.54 7.86h12.09c5.42 0 7.54-1.74 7.54-7.86v-1.19c0-.71.38-1.08 1.08-1.08h3.15c.71 0 1.08.38 1.08 1.03v1.08c0 8.41-3.53 13.18-12.85 13.18h-12.09c-9.33 0-12.85-4.77-12.85-13.18Zm73.43-5.26v17.41c0 .71-.38 1.08-1.08 1.08h-2.93c-.71 0-1.08-.38-1.08-1.08V22.29c0-5.59-1.19-6.78-6.24-6.78h-7.7c-4.23 0-6.18.98-6.18 6.78v17.79c0 .71-.38 1.08-1.08 1.08h-2.93c-.71 0-1.08-.38-1.08-1.08v-39c0-.71.38-1.08 1.08-1.08h2.93c.71 0 1.08.38 1.08 1.08v13.56c1.19-2.66 3.63-3.96 8.57-3.96h5.42c9.06 0 11.23 3.96 11.23 12.04Zm4.17 10.03c0-5.91 2.33-8.41 9.71-9.22l13.45-1.46c1.3-.16 1.74-.87 1.74-2.17 0-3.47-1.03-4.39-5.59-4.39h-15.78c-.71 0-1.08-.38-1.08-1.08v-2.66c0-.71.38-1.08 1.08-1.08h15.89c7.81 0 10.58 2.77 10.58 8.95V40.1c0 .71-.38 1.08-1.08 1.08h-2.93c-.71 0-1.08-.38-1.08-1.08v-3.58c-1.41 3.2-3.47 4.66-9.44 4.66h-4.07c-7.27 0-11.39-2.6-11.39-8.41Zm17.52 3.69c5.64 0 7.38-1.95 7.38-7.05v-2.98l-14.37 1.52c-4.34.43-5.37 1.46-5.37 4.39 0 2.66 1.9 4.12 6.24 4.12h6.13Zm18 3.63v-2.66c0-.71.38-1.08 1.08-1.08h15.51c4.83 0 6.18-.98 6.18-3.74s-.92-3.47-5.32-3.91l-9.11-.92c-6.94-.71-9-3.36-9-8.79 0-5.69 3.31-8.3 10.9-8.3h15.08c.71 0 1.08.38 1.08 1.08v2.66c0 .71-.38 1.08-1.08 1.08h-14.97c-4.39 0-5.91 1.08-5.91 3.85 0 2.55.81 3.31 4.77 3.74l9 .98c7.81.87 9.71 3.69 9.71 8.95 0 5.91-3.25 8.14-11.39 8.14H288.9c-.71 0-1.08-.38-1.08-1.08Zm31.99-10.96v-6.56c0-7.86 2.17-11.88 11.23-11.88h7.65c9.06 0 11.23 4.01 11.23 11.88v4.88c0 .71-.38 1.08-1.08 1.08h-23.92v1.03c0 5.59 1.19 6.78 6.24 6.78h15.24c.71 0 1.08.38 1.08 1.08v2.66c0 .71-.38 1.08-1.08 1.08h-15.35c-9.06 0-11.23-3.96-11.23-12.04Zm25-5.21v-1.74c0-5.48-1.19-6.67-6.24-6.67h-7.43c-5.04 0-6.24 1.19-6.24 6.67v1.74h19.9Zm28.79-13.23c.71 0 1.08.38 1.08 1.08v2.66c0 .71-.38 1.08-1.08 1.08h-7.38c-4.28 0-6.24.98-6.24 6.78v17.79c0 .71-.38 1.08-1.08 1.08h-2.93c-.71 0-1.08-.38-1.08-1.08v-28.3c0-.71.38-1.08 1.08-1.08h2.93c.71 0 1.08.38 1.08 1.08v2.87c1.19-2.66 3.69-3.96 8.62-3.96h4.99Z"/><path fill="#9aca3c" d="M159.32 2.2h-25.37a2.906 2.906 0 0 0-2.85 3.5v32.19a2.906 2.906 0 0 0 2.85 3.5h25.37c5.39 0 9.77-4.38 9.77-9.77V11.97c0-5.39-4.38-9.77-9.77-9.77Zm3.95 29.42c0 2.18-1.77 3.95-3.95 3.95h-22.4V8.02h22.4c2.18 0 3.95 1.77 3.95 3.96v19.64ZM46.75 11.85v6.89h25.74c1.6 0 2.9 1.3 2.9 2.9s-1.3 2.9-2.9 2.9H46.75v6.89c0 2.17 1.77 3.94 3.94 3.94h25.28c1.6 0 2.9 1.3 2.9 2.9s-1.3 2.9-2.9 2.9H50.69c-5.37 0-9.74-4.37-9.74-9.74V11.85c0-5.37 4.37-9.74 9.74-9.74h25.28c1.6 0 2.9 1.3 2.9 2.9s-1.3 2.9-2.9 2.9H50.69c-2.17 0-3.94 1.77-3.94 3.94Zm-8.83 26.42c0 1.6-1.3 2.9-2.9 2.9H9.74C4.37 41.17 0 36.8 0 31.43V11.85l.02.04V5.01c0-1.6 1.3-2.9 2.9-2.9s2.9 1.3 2.9 2.9v23c0 .06-.01.12-.02.17v3.25c0 2.17 1.77 3.94 3.94 3.94h25.28c1.6 0 2.9 1.3 2.9 2.9Zm77-35.05H95c-5.46 0-9.91 4.44-9.91 9.91v25.72a2.949 2.949 0 1 0 5.9 0V25.46h27.93v13.39a2.949 2.949 0 1 0 5.9 0V13.12c0-5.46-4.44-9.91-9.91-9.91ZM90.99 19.56v-6.43c0-2.21 1.8-4.01 4.01-4.01h19.92c2.21 0 4.01 1.8 4.01 4.01v6.43H91Z"/></svg></h2> <p><a href="#LEADChaser" class="scrollto">LEADChaser</a> combines DEL screening with medicinal chemistry to streamline progression from hit-to-lead to candidate. Because we know DEL chemistry so well, no one can compete with our efficiency in following up DEL hits. With our <a href="#LEADChaser" class="scrollto">LEADChaser</a> solutions, our chemists use SAR insights generated in the DEL screen to progress your most promising DEL outputs in rapid design and test loops. By focusing on compound quality and developability, we avoid dead ends and deliver high- quality matter, faster. Avoid hand-offs and move through hit-to-lead with unprecedented speed and clarity using <a href="#LEADChaser" class="scrollto">LEADChaser</a>.</p> <p style="text-align:center;margin:0;"><a href="#LEADChaser" class="btn reverse scrollto">Learn More</a></p> </div> </div> <div id="medchem-ai-content" class="xd3-content"> <div class="xd3-content-inside"> <div class="xd3-close close"></div> <h2><svg viewBox="0 0 363.51 42.94" height="36" width="305"><title>DRUGFinder</title><path fill="#fff" d="M215.99 4.09v3.08c0 .73-.39 1.12-1.12 1.12h-25.96v11.49h17.6c.73 0 1.12.39 1.12 1.12v2.92c0 .73-.39 1.12-1.12 1.12h-17.6v16.48c0 .73-.39 1.12-1.12 1.12h-3.25c-.73 0-1.12-.39-1.12-1.12V4.09c0-.73.39-1.12 1.12-1.12h30.33c.73 0 1.12.39 1.12 1.12Zm8.46 6.95h-3.03c-.73 0-1.12.39-1.12 1.12v29.27c0 .73.39 1.12 1.12 1.12h3.03c.73 0 1.12-.39 1.12-1.12V12.17c0-.73-.39-1.12-1.12-1.12Zm0-11.04h-3.03c-.73 0-1.12.39-1.12 1.12v5.33c0 .73.39 1.12 1.12 1.12h3.03c.73 0 1.12-.39 1.12-1.12V1.12c0-.73-.39-1.12-1.12-1.12Zm27.24 11.04h-5.55c-5.1 0-7.68 1.35-8.91 4.09v-2.97c0-.73-.39-1.12-1.12-1.12h-3.03c-.73 0-1.12.39-1.12 1.12v29.27c0 .73.39 1.12 1.12 1.12h3.03c.73 0 1.12-.39 1.12-1.12V23.04c0-6 2.02-7.01 6.45-7.01h7.96c5.16 0 6.39 1.23 6.39 7.01v18.45c0 .73.39 1.12 1.12 1.12h3.03c.73 0 1.12-.39 1.12-1.12v-18c0-8.35-2.24-12.45-11.61-12.45Zm49.38-9.92v40.31c0 .73-.39 1.12-1.12 1.12h-3.03c-.73 0-1.12-.39-1.12-1.12v-2.97c-1.23 2.75-3.76 4.09-8.86 4.09h-6.73c-9.36 0-11.61-4.15-11.61-12.28v-6.78c0-8.35 2.24-12.45 11.61-12.45h6.73c5.1 0 7.62 1.35 8.86 4.09V1.12c0-.73.39-1.12 1.12-1.12h3.03c.73 0 1.12.39 1.12 1.12Zm-5.27 21.92c0-6-2.02-7.01-6.39-7.01h-9.08c-5.21 0-6.45 1.23-6.45 7.01v7.62c0 5.66 1.23 6.9 6.45 6.9h9.08c4.37 0 6.39-1.01 6.39-6.9v-7.62Zm42.09.28v5.05c0 .73-.39 1.12-1.12 1.12h-24.72v1.07c0 5.77 1.23 7.01 6.45 7.01h15.75c.73 0 1.12.39 1.12 1.12v2.75c0 .73-.39 1.12-1.12 1.12h-15.87c-9.36 0-11.61-4.09-11.61-12.45v-6.78c0-8.13 2.24-12.28 11.61-12.28h7.91c9.36 0 11.61 4.15 11.61 12.28Zm-5.27-.39c0-5.66-1.23-6.9-6.45-6.9h-7.68c-5.21 0-6.45 1.23-6.45 6.9v1.79h20.58v-1.79Zm29.76-11.89h-5.16c-5.1 0-7.68 1.35-8.91 4.09v-2.97c0-.73-.39-1.12-1.12-1.12h-3.03c-.73 0-1.12.39-1.12 1.12v29.27c0 .73.39 1.12 1.12 1.12h3.03c.73 0 1.12-.39 1.12-1.12V23.04c0-6 2.02-7.01 6.45-7.01h7.62c.73 0 1.12-.39 1.12-1.12v-2.75c0-.73-.39-1.12-1.12-1.12Z"/><path fill="#ef4379" d="M131.56 5.51v26.58c0 5.65-4.59 10.24-10.24 10.24h-20.59c-5.65 0-10.24-4.59-10.24-10.24V5.51a3.05 3.05 0 1 1 6.1 0v26.58c0 2.28 1.86 4.14 4.14 4.14h20.59c2.29 0 4.14-1.86 4.14-4.14V5.51c0-1.68 1.36-3.05 3.05-3.05s3.05 1.36 3.05 3.05ZM85.1 12.24v2.6c0 4.59-3.08 8.46-7.27 9.69l.25.59 5.67 13.28a3.048 3.048 0 1 1-5.61 2.39l-6.77-15.86h-19.5v14.94a3.05 3.05 0 1 1-6.1 0V5.75c0-.1.02-.2.03-.3-.01-.1-.03-.2-.03-.3 0-1.66 1.35-3.01 3.01-3.01H75c5.57 0 10.1 4.53 10.1 10.1Zm-6.02 0c0-2.25-1.83-4.09-4.09-4.09H51.86v10.78h23.13c2.25 0 4.09-1.83 4.09-4.09v-2.6Zm-39.75 0v20.31c0 5.57-4.53 10.1-10.1 10.1H3.01a3.013 3.013 0 0 1-2.95-3.62V5.76a3.013 3.013 0 0 1 2.95-3.62h26.22c5.57 0 10.1 4.53 10.1 10.1Zm-6.02 0c0-2.25-1.83-4.09-4.09-4.09H6.08v28.48h23.15c2.25 0 4.09-1.83 4.09-4.09V12.25Zm140.94 7.1h-15.17c-1.68 0-3.05 1.37-3.05 3.05s1.37 3.05 3.05 3.05h12.12v11.1h-23.11c-2.25 0-4.09-1.83-4.09-4.09V12.17c0-2.25 1.83-4.09 4.09-4.09h26.21c1.66 0 3.01-1.35 3.01-3.01s-1.35-3.01-3.01-3.01h-26.21c-5.57 0-10.1 4.53-10.1 10.1v20.3c0 5.57 4.53 10.1 10.1 10.1h26.21c1.66 0 3.01-1.35 3.01-3.01 0-.08-.02-.15-.02-.22 0-.08.02-.15.02-.22V22.4a3.04 3.04 0 0 0-3.05-3.04Z"/></svg></h2> <p><a href="#DRUGFinder" class="scrollto">DRUGFinder</a> accelerates medicinal chemistry through use of ArtemisAI’s predictive models for key pharmacological parameters. <a href="https://www.x-chemrx.com/artemisai/" style="color: #2aa1db;"><strong style="color: #2aa1db;">ArtemisAI</strong></a> helps scientists tame the challenge of multivariable optimization by giving accurate predictions across key physicochemical and ADME properties and prioritizing compounds for synthesis and testing. With our <a href="#DRUGFinder" class="scrollto">DRUGFinder</a> solution, we combine expert medicinal chemistry with the industry’s leading AI platform to deliver game-changing acceleration to your drug discovery.</p> <p style="text-align:center;margin:0;"><a href="#DRUGFinder" class="btn reverse scrollto">Learn More</a></p> </div> </div> <div id="ai-content" class="xd3-content"> <div class="xd3-content-inside"> <div class="xd3-close close"></div> <svg viewBox="0 0 303.06 54.67" width="200" height="36"><title>Artemis AI</title><path fill="#fff" d="M67.98 24.46v2.69c0 .72-.38 1.1-1.1 1.1h-7.47c-4.34 0-6.31.99-6.31 6.86v18.01c0 .71-.38 1.1-1.1 1.1h-2.96c-.71 0-1.1-.38-1.1-1.1V24.46c0-.71.38-1.1 1.1-1.1H52c.71 0 1.1.38 1.1 1.1v2.91c1.21-2.69 3.73-4.01 8.73-4.01h5.05c.71 0 1.1.38 1.1 1.1Zm24.92-1.1H80.27v-6.81c0-.71-.38-1.1-1.1-1.1h-1.43c-.71 0-1.1.38-1.1 1.15-.05 6.26-.44 6.7-4.94 6.75-.71 0-1.1.38-1.1 1.1v2.58c0 .71.38 1.1 1.1 1.1h3.4v14.44c0 7.69 2.25 11.64 12.19 11.64h5.6c.71 0 1.1-.38 1.1-1.1v-2.58c0-.71-.38-1.1-1.1-1.1h-5.6c-5.49 0-7.03-1.48-7.03-6.42V28.13h12.63c.71 0 1.1-.38 1.1-1.1v-2.58c0-.71-.38-1.1-1.1-1.1Zm34.98 12.02v4.94c0 .72-.38 1.1-1.1 1.1h-24.21v1.04c0 5.66 1.21 6.86 6.31 6.86h15.43c.71 0 1.1.38 1.1 1.1v2.69c0 .71-.38 1.1-1.1 1.1h-15.54c-9.17 0-11.36-4.01-11.36-12.19v-6.64c0-7.96 2.2-12.02 11.36-12.02h7.74c9.17 0 11.36 4.06 11.36 12.02Zm-5.16-.38c0-5.54-1.21-6.75-6.31-6.75h-7.52c-5.11 0-6.31 1.21-6.31 6.75v1.76h20.15V35Zm45.33-11.64h-1.21c-5.22 0-8.18 1.48-9.66 4.45-1.48-3.13-4.56-4.45-9.77-4.45h-1.21c-5 0-7.52 1.32-8.73 4.01v-2.91c0-.71-.38-1.1-1.1-1.1h-2.96c-.71 0-1.1.38-1.1 1.1v28.66c0 .71.38 1.1 1.1 1.1h2.96c.71 0 1.1-.38 1.1-1.1V35.11c0-5.87 1.98-6.86 6.31-6.86h3.13c5.05 0 6.26 1.21 6.26 6.86v18.06c0 .71.38 1.1 1.1 1.1h2.96c.71 0 1.1-.38 1.1-1.1V35.11c0-5.87 1.98-6.86 6.31-6.86h3.13c5.05 0 6.31 1.21 6.31 6.86v18.06c0 .71.38 1.1 1.1 1.1h2.96c.71 0 1.1-.38 1.1-1.1V35.55c0-8.18-2.31-12.19-11.2-12.19Zm20.57 0h-2.96c-.71 0-1.1.38-1.1 1.1v28.66c0 .71.38 1.1 1.1 1.1h2.96c.71 0 1.1-.38 1.1-1.1V24.46c0-.71-.38-1.1-1.1-1.1Zm0-10.81h-2.96c-.71 0-1.1.38-1.1 1.1v5.22c0 .71.38 1.1 1.1 1.1h2.96c.71 0 1.1-.38 1.1-1.1v-5.22c0-.71-.38-1.1-1.1-1.1Zm24.68 24.37-9.11-.99c-4.01-.44-4.83-1.21-4.83-3.79 0-2.8 1.54-3.9 5.98-3.9h15.15c.71 0 1.1-.38 1.1-1.1v-2.69c0-.71-.38-1.1-1.1-1.1h-15.26c-7.69 0-11.03 2.64-11.03 8.4s2.09 8.18 9.11 8.89l9.22.93c4.45.44 5.38 1.15 5.38 3.95s-1.37 3.79-6.26 3.79h-15.7c-.71 0-1.1.38-1.1 1.1v2.69c0 .71.38 1.1 1.1 1.1h15.65c8.23 0 11.53-2.25 11.53-8.24 0-5.32-1.92-8.18-9.83-9.06ZM22.23 13.59a2.706 2.706 0 0 0-3.64 1.18L.3 50.62a2.706 2.706 0 0 0 1.18 3.64 2.711 2.711 0 0 0 3.65-1.18l18.28-35.85c.68-1.33.15-2.96-1.18-3.64Zm6.57 10.96A2.707 2.707 0 1 0 23.97 27l7.76 15.34H16.2c-1.28 0-2.32 1.04-2.32 2.32s1.04 2.32 2.32 2.32h17.88l3.09 6.1a2.72 2.72 0 0 0 2.42 1.49A2.705 2.705 0 0 0 42 50.64L28.81 24.56Z"/><path fill="#2ba0da" d="M279.55 16v35.96c0 1.5-1.21 2.71-2.71 2.71s-2.71-1.21-2.71-2.71V16c0-1.5 1.21-2.71 2.71-2.71s2.71 1.21 2.71 2.71Zm-30.13-2.41a2.706 2.706 0 0 0-3.64 1.18l-18.29 35.85a2.706 2.706 0 0 0 1.18 3.64 2.711 2.711 0 0 0 3.65-1.18l18.29-35.85c.68-1.33.15-2.96-1.18-3.64Zm6.57 10.96a2.71 2.71 0 0 0-3.64-1.19c-1.33.67-1.87 2.3-1.19 3.64l7.76 15.34h-15.53c-1.28 0-2.32 1.04-2.32 2.32s1.04 2.32 2.32 2.32h17.88l3.09 6.1a2.72 2.72 0 0 0 2.42 1.49 2.705 2.705 0 0 0 2.41-3.93L256 24.56Zm47.07-23.1v12.71c0 .8-.65 1.45-1.45 1.45h-12.72c-.8 0-1.45-.65-1.45-1.45V1.45c0-.8.65-1.45 1.45-1.45h12.72c.8 0 1.45.65 1.45 1.45Zm-2.9 1.45h-9.82v9.82h9.82V2.9Z"/></svg> <p>We coupled our high-quality DEL data and medicinal chemistry expertise with the innovative artificial intelligence capabilities of <a href="https://www.x-chemrx.com/artemisai/">ArtemisAI</a> to provide machine learning-driven drug discovery. We accelerate drug discovery programs and get medicines to patients faster by unlocking the full potential of rich datasets to identify and optimize high-quality starting points.</p> <p style="text-align:center;margin:0;"><a href="https://www.x-chemrx.com/artemisai/" class="btn reverse">Learn More</a></p> </div> </div> <div id="del-content" class="xd3-content"> <div class="xd3-content-inside"> <div class="xd3-close close"></div> <h2>DEL Technologies</h2> <p>X-Chem leverages its expertise as a DEL pioneer via <a href="https://www.x-chemrx.com/delcore/">DELcore</a>, our full-service discovery partnership, or with <a href="https://www.x-chemrx.com/delflex/">DELflex</a>, our popular easy access model. With nearly 100 programs licensed, we have an unrivaled track record of delivering value to our partners and clients. Wielding over 125 billion molecules and proprietary tagging approaches, we enable you to investigate a hugely diverse range of molecules. Our game-changing DEL platform and decade of experience in DEL-driven discovery yields unrivaled performance and success — with unprecedented speed and clarity.</p> <p style="text-align:center;margin:0;"><a href="https://www.x-chemrx.com/del-overview/" class="btn reverse">Learn More</a></p> </div> </div> <div id="medchem-content" class="xd3-content"> <div class="xd3-content-inside"> <div class="xd3-close close"></div> <h2>Medicinal Chemistry</h2> <p>The X-Chem medicinal chemistry teams — with facilities in the United States, Canada and Europe — put their extensive experience to work, converting screening results into outstanding drug leads and candidates. We know from experience that successful medicinal chemistry is about more than chasing potency. Our teams focus on the physical properties, DMPK and developability of your hits from Day One — transitioning from hit to candidate in record time.</p> <p style="text-align:center;margin:0;"><a href="https://www.x-chemrx.com/medicinal-chemistry/" class="btn reverse">Learn More</a></p> </div> </div> </div> </div> </div> </div> </div> <div class="wp-block-kadence-rowlayout alignwide" id="HITMiner"><div id="kt-layout-id_c9fe07-b3" class="kt-row-layout-inner kt-layout-id_c9fe07-b3"><div class="kt-row-column-wrap kt-has-2-columns kt-gutter-default kt-v-gutter-default kt-row-valign-top kt-row-layout-equal kt-tab-layout-inherit kt-m-colapse-left-to-right kt-mobile-layout-row"> <div class="wp-block-kadence-column inner-column-1 kadence-column_9d0b9a-af"><div class="kt-inside-inner-col"><div class="wp-block-image"> <figure class="aligncenter size-large is-resized"><img width="350" height="211" decoding="async" src="data:image/svg+xml,%3Csvg%20xmlns='http://www.w3.org/2000/svg'%20viewBox='0%200%20350%20211'%3E%3C/svg%3E" alt="HITMiner" class="wp-image-21573" data-lazy-src="https://www.x-chemrx.com/wp-content/uploads/2022/03/HITMiner.svg"/><noscript><img width="350" height="211" decoding="async" src="https://www.x-chemrx.com/wp-content/uploads/2022/03/HITMiner.svg" alt="HITMiner" class="wp-image-21573"/></noscript></figure></div></div></div> <div class="wp-block-kadence-column inner-column-2 kadence-column_dd2afa-28"><div class="kt-inside-inner-col"> <h2 class="wp-block-heading"><strong>AI With DNA-Encoded Library (DEL) Data</strong></h2> <p>By applying <a href="https://www.x-chemrx.com/artemisai/">ArtemisAI’s</a> leading AI platform to the depth of DNA-Encoded Library (DEL) screening data, we can predict new binders and expand the scope of chemical space accessed for hit generation.</p> <p>Drug discovery is a process based on attrition. Having multiple starting points provides more information and increases the odds of finding clinical candidates faster. HITMiner maximizes the scope of hit generation, supplying our partners with the maximum number of shots on goal.</p> <p>We were the first to demonstrate and publish on the generation and use of DEL-trained AI models for hit identification (<a href="https://dx.doi.org/10.1021/acs.jmedchem.0c00452" target="_blank" rel="noreferrer noopener">see 2020 paper</a>). We can apply that same powerful capability to partner programs.</p> <p>Our scientists are <a href="https://www.x-chemrx.com/del-track-record/">widely recognized leaders in DEL</a> and <a href="https://www.x-chemrx.com/artemisai/">AI for drug discovery</a>. We have pushed the boundaries in DEL technology and AI for small molecule discovery. HITMiner combines these fields into one powerful solution to jump-start your small molecule discovery.</p> <p>Accelerate your drug discovery program by getting more hits, faster, using HITMiner<strong>.</strong></p> <p><a href="https://www.x-chemrx.com/resources/hitminer-benefits-of-ai-with-del-data/">Learn more</a> about the Benefits of AI with DEL Data</p> </div></div> </div></div></div> <div class="wp-block-kadence-rowlayout alignwide" id="LEADChaser"><div id="kt-layout-id_5d539a-22" class="kt-row-layout-inner kt-layout-id_5d539a-22"><div class="kt-row-column-wrap kt-has-2-columns kt-gutter-default kt-v-gutter-default kt-row-valign-top kt-row-layout-equal kt-tab-layout-inherit kt-m-colapse-left-to-right kt-mobile-layout-row"> <div class="wp-block-kadence-column inner-column-1 kadence-column_ed4ee1-d6"><div class="kt-inside-inner-col"><div class="wp-block-image"> <figure class="aligncenter size-large is-resized"><img width="350" height="211" decoding="async" src="data:image/svg+xml,%3Csvg%20xmlns='http://www.w3.org/2000/svg'%20viewBox='0%200%20350%20211'%3E%3C/svg%3E" alt="LEADChaser" class="wp-image-21574" data-lazy-src="https://www.x-chemrx.com/wp-content/uploads/2022/03/LEADChaser.svg"/><noscript><img width="350" height="211" decoding="async" src="https://www.x-chemrx.com/wp-content/uploads/2022/03/LEADChaser.svg" alt="LEADChaser" class="wp-image-21574"/></noscript></figure></div></div></div> <div class="wp-block-kadence-column inner-column-2 kadence-column_8229a4-94"><div class="kt-inside-inner-col"> <h2 class="wp-block-heading"><strong>Fusing DNA-Encoded Library (DEL) Screening and Medicinal Chemistry</strong></h2> <p>Combine DNA-Encoded Library (DEL) screening with medicinal chemistry to streamline progression from hit to lead to candidate. Discovering high-quality hits from DEL screening is only the first step in drug discovery; LEADChaser taps into X-Chem’s medicinal chemistry expertise to rapidly progress hits into leads and candidates.</p> <p>X-Chem’s <a href="https://www.x-chemrx.com/del-overview/">DEL</a> platform has been deployed extensively in support of pharmaceutical discovery. X-Chem’s <a href="https://www.x-chemrx.com/medicinal-chemistry/">medicinal chemistry</a> team is a renowned group of experienced researchers with a strong track record of success. Putting these two capabilities together streamlines your drug discovery.</p> <p>X-Chem has delivered over 90 hit programs with multiple series to our pharma partners. Our team members have led or contributed to 14 clinical candidates. Our medicinal chemistry team is responsible for delivering two candidates and 10 patents in 2021 alone.</p> <p>Avoid handoffs and move through hit-to-lead, faster, by using LEADChaser.</p> </div></div> </div></div></div> <div class="wp-block-kadence-rowlayout alignwide" id="DRUGFinder"><div id="kt-layout-id_4dca58-4a" class="kt-row-layout-inner kt-layout-id_4dca58-4a"><div class="kt-row-column-wrap kt-has-2-columns kt-gutter-default kt-v-gutter-default kt-row-valign-top kt-row-layout-equal kt-tab-layout-inherit kt-m-colapse-left-to-right kt-mobile-layout-row"> <div class="wp-block-kadence-column inner-column-1 kadence-column_0f6619-4a"><div class="kt-inside-inner-col"><div class="wp-block-image"> <figure class="aligncenter size-large is-resized"><img width="350" height="211" decoding="async" src="data:image/svg+xml,%3Csvg%20xmlns='http://www.w3.org/2000/svg'%20viewBox='0%200%20350%20211'%3E%3C/svg%3E" alt="DRUGFinder" class="wp-image-21572" data-lazy-src="https://www.x-chemrx.com/wp-content/uploads/2022/03/DRUGFinder.svg"/><noscript><img width="350" height="211" decoding="async" src="https://www.x-chemrx.com/wp-content/uploads/2022/03/DRUGFinder.svg" alt="DRUGFinder" class="wp-image-21572"/></noscript></figure></div></div></div> <div class="wp-block-kadence-column inner-column-2 kadence-column_9b4fde-1b"><div class="kt-inside-inner-col"> <h2 class="wp-block-heading"><strong>Combining Medicinal Chemistry and AI</strong></h2> <p>Accelerate medicinal chemistry through use of <a href="https://www.x-chemrx.com/artemisai/">ArtemisAI’s</a> predictive models for key pharmacological parameters. X-Chem combines the use of AI in drug discovery with the expertise of our medicinal chemists to enhance your drug hunting possibilities.</p> <p><a href="https://www.x-chemrx.com/medicinal-chemistry/">Medicinal chemistry</a> is a multiparameter optimization problem that gets increasingly complex as it progresses. ArtemisAI helps scientists tame the multivariable problem by giving accurate predictions across key parameters, such as physicochemical and ADME properties.</p> <p>ArtemisAI has been trained on the largest available dataset, including our diverse chemical compound libraries, and has proven accuracy. X-Chem’s med chem group builds on its extensive expertise by applying ArtemisAI to key challenges in lead optimization. The result is better compounds and faster progression to candidate.</p> <p>Our medicinal chemistry team is responsible for two candidates in 2021 that were delivered in under three years. ArtemisAI has demonstrated its power in generative designs of novel hits, and in accurate prediction of key properties. The combination of these two expert capabilities will deliver game-changing acceleration to your drug discovery.</p> <p>Accelerate multiparameter optimization by combining expert medicinal chemistry with the industry’s leading AI platform.</p> </div></div> </div></div></div> </div> </div> </article> </main> </div> </div>  </div> <div data-wpr-lazyrender="1" id="pre-foot"> <div class="pre-foot-content"> <h3 id="foot-cta">Small Molecules Hold Exponential Possibilities <strong>Find Your Next Drug Candidate With X-Chem</strong></h3> <a id="foot-cta-link" href="https://www.x-chemrx.com/contact-us/" target="" class="btn reverse">Talk To Us</a> </div> </div> <footer data-wpr-lazyrender="1" id="colophon" class="site-footer"> <div class="foot-content row"> <div id="site-info" class="site-info foot-part"> <div class="site-info-row"> <p id="copyright-statement">© 2024 X-Chem. 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