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Pathways and Diagrams by Research Area | Cell Signaling Technology
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aria-hidden="true"></i> </div> </form> </div> </div> <div class="shield"></div> </header> <main class="container-fluid "> <span class="hide" id="data-helper" data-page-id="by-research-area" data-media-url="media.cellsignal.com" data-file-version="76.5.0"></span> <div><!-- start content cartridge "content-slot" --> <!-- DEBUG: TemplateSubcategory.jsp --> <div class="row"> <div class="col-xs-12"> <!-- pathwayDiagram:pathway_522 --> <!-- Otherwise --> <div class="hide" data-NOLOG="TRUE"></div> <nav data-template="content-breadcrumb-block"> <ol class="breadcrumb"> <li> <a href="/" class="link-inverse">Home</a></li> <li> <a href="/pathways" class="link-inverse">Pathways</a></li> <li>Pathways and Diagrams by Research Area</li> </ol> </nav> <div data-template="content-page-header"> <h1>Pathways and Diagrams by Research Area</h1> </div> </div> </div> <div class="row" data-template="subcategory"> <div class="col-md-8"> <div data-template="content-html-block"> <img alt="Pathways by research area" class="img-responsive" src="//media.cellsignal.com/www/images/pathways/by-research-area-144-px.jpg" /></p> <p class="p-empty extra-top-spacing">Explore these collections of interactive signaling pathways, diagrams, research guides, relevant products, publications, and other resources organized by research area topic. The interactive pathways and diagrams have been created by CST scientists and outside experts to provide concise overviews of selected signaling pathways and cellular mechanisms. Protein nodes in each interactive diagram are linked to specific antibody product information, as well as protein-specific listings in the PhosphoSitePlus<sup>®</sup> database of post-translational modifications so you can quickly identify products for your research.<div class="showMoreWrapper"> <a id="showMoreButton" class="showMoreButtonHidden" data-toggle="contentHtmlBlockModal" onclick="showMoreModal('content')" data-toggle="modal">Show More</a> </div> </div> <div id="center-accordionGroup" role="tablist" aria-multiselectable="true" data-template="content-center-accordians-group"> <div class="centerAccordiansGroup"> <div class="openAllCheckBox" style="display:none;"> <span role="button" class="toggle-button"> <input type="checkbox" class="pcdisabled"> <span class="slider"></span> <span class="text"> <span class="open-text">Open</span> <span class="close-text">Close</span> All</span> </span> </div> <div class="accordionGroup"> <h2>Research Area</h2> <div class="accordionGroupHeading" role="tab" id="heading00"> <h3> <a role="button" data-toggle="collapse" href="#collapse00" aria-expanded="false" aria-controls="collapse00"> Adhesion/ECM/Cytoskeleton</a> </h3> </div> <div id="collapse00" class="collapse" role="tabpanel" aria-labelledby="heading00"> <div class="accordionGroupBody"> <p></p> <ul> <li><a href="/pathways/by-research/adhesion-ecm-cytoskeleton-pathways">Adhesion/ECM/Cytoskeleton</a></li> <li><a href="/pathways/adherens-junction-dynamics-pathway">Adherens Junction Dynamics</a></li> <li><a href="/pathways/contribution-extracellular-matrix-emt">Contribution of Extracellular Matrix to EMT</a></li> <li><a href="/pathways/contribution-soluble-factors-emt">Contribution of Soluble Factors to EMT</a></li> <li><a href="/pathways/tumor-angiogenesis-pathway">Tumor Angiogenesis</a></li> <li><a href="/pathways/mechanisms-of-fibrosis-pathway">Mechanisms of Fibrosis</a></li> <li><a href="/pathways/regulation-of-actin-dynamics">Regulation of Actin Dynamics</a></li> <li><a href="/pathways/regulation-of-microtubule-dynamics">Regulation of Microtubule Dynamics</a></li> </ul> </div> </div> <div class="accordionGroupHeading" role="tab" id="heading01"> <h3> <a role="button" data-toggle="collapse" href="#collapse01" aria-expanded="false" aria-controls="collapse01"> Cell Cycle Regulation</a> </h3> </div> <div id="collapse01" class="collapse" role="tabpanel" aria-labelledby="heading01"> <div class="accordionGroupBody"> <p></p> <ul> <li><a href="/pathways/by-research/cell-cycle-regulation-pathways">Cell Cycle Regulation</a></li> <li><a href="/pathways/dna-damage-response-pathway">DNA Damage Response</a></li> <li><a href="/pathways/g2m-dna-damage-checkpoint-pathway">G2M/DNA Damage Checkpoint</a></li> <li><a href="/pathways/g1-s-checkpoint-pathway">G1/S Checkpoint</a></li> <li><a href="/pathways/senescence-signaling-pathway">Senescence Signaling</a></li> </ul> </div> </div> <div class="accordionGroupHeading" role="tab" id="heading02"> <h3> <a role="button" data-toggle="collapse" href="#collapse02" aria-expanded="false" aria-controls="collapse02"> Cell Death</a> </h3> </div> <div id="collapse02" class="collapse" role="tabpanel" aria-labelledby="heading02"> <div class="accordionGroupBody"> <p></p> <ul> <li><a href="/pathways/by-research/cell-death-pathways">Cell Death</a></li> <li><a href="/pathways/regulation-of-apoptosis-pathway">Regulation of Apoptosis</a></li> <li><a href="/pathways/death-receptor-signaling">Death Receptor Signaling</a></li> <li><a href="/pathways/mitochondrial-control-of-apoptosis">Mitochondrial Control of Apoptosis</a></li> <li><a href="/pathways/inhibition-of-apoptosis-pathway">Inhibition of Apoptosis</a></li> <li><a href="/pathways/necrotic-cell-death-pathway">Necrotic Cell Death</a></li> <li><a href="/pathways/autophagy-signaling-pathway">Autophagy Signaling</a></li> <li><a href="/pathways/senescence-signaling-pathway">Senescence Signaling</a></li> </ul> </div> </div> <div class="accordionGroupHeading" role="tab" id="heading03"> <h3> <a role="button" data-toggle="collapse" href="#collapse03" aria-expanded="false" aria-controls="collapse03"> Cellular Metabolism</a> </h3> </div> <div id="collapse03" class="collapse" role="tabpanel" aria-labelledby="heading03"> <div class="accordionGroupBody"> <p></p> <ul> <li><a href="/pathways/autophagy-signaling-pathway">Autophagy Signaling</a></li> <li><a href="/pathways/insulin-receptor-signaling-pathway">Insulin Receptor Signaling</a></li> <li><a href="/pathways/warburg-effect-pathway">Warburg Effect</a></li> <li><a href="/pathways/hypoxia-signaling-pathway">Hypoxia Signaling</a></li> <li><a href="/pathways/glutamine-metabolism">Glutamine Metabolism</a></li> <li><a href="/pathways/mtor-signaling-pathway">mTOR Signaling</a></li> <li><a href="/pathways/ampk-signaling-pathway">AMPK Signaling</a></li> <li><a href="/pathways/senescence-signaling-pathway">Senescence Signaling</a></li> <li><a href="/pathways/mechanisms-of-fibrosis-pathway">Mechanisms of Fibrosis</a></li> </ul> </div> </div> <div class="accordionGroupHeading" role="tab" id="heading04"> <h3> <a role="button" data-toggle="collapse" href="#collapse04" aria-expanded="false" aria-controls="collapse04"> Developmental Biology Signaling</a> </h3> </div> <div id="collapse04" class="collapse" role="tabpanel" aria-labelledby="heading04"> <div class="accordionGroupBody"> <p></p> <ul> <li><a href="/pathways/by-research/developmental-biology-signaling-pathways">Developmental Biology Signaling</a></li> <li><a href="/pathways/wnt-beta-catenin-signaling-pathway">Wnt/β-Catenin Signaling</a></li> <li><a href="/pathways/tgf-beta-signaling-pathway">TGF-β Signaling</a></li> <li><a href="/pathways/hedgehog-signaling-pathway">Hedgehog Signaling</a></li> <li><a href="/pathways/notch-signaling-pathway">Notch Signaling</a></li> <li><a href="/pathways/hippo-signaling-pathway">Hippo Signaling</a></li> <li><a href="/pathways/angiogenesis-pathway">Angiogenesis</a></li> <li><a href="/pathways/pluripotency-and-differentiation-pathway">Pluripotency and Differentiation</a></li> </ul> </div> </div> <div class="accordionGroupHeading" role="tab" id="heading05"> <h3> <a role="button" data-toggle="collapse" href="#collapse05" aria-expanded="false" aria-controls="collapse05"> Epigenetics</a> </h3> </div> <div id="collapse05" class="collapse" role="tabpanel" aria-labelledby="heading05"> <div class="accordionGroupBody"> <p></p> <ul> <li><a href="/pathways/by-research/epigenetics-pathways">Epigenetics</a></li> <li><a href="/pathways/dna-methylation-pathway">DNA Methylation</a></li> <li><a href="/pathways/chromatin-methylation-pathway">Histone Methylation</a></li> <li><a href="/pathways/chromatin-acetylation-pathway">Protein Acetylation</a></li> <li><a href="/pathways/chromatin-crosstalk-pathway">Crosstalk Between Post-translational Modifications</a></li> <li><a href="/pathways/epigenetic-histone-h2a-h2b-h4-pathway">Writers & Erasers of Histones H2A, H2B, and H4</a></li> <li><a href="/pathways/epigenetic-histone-h3-pathway">Epigenetic Writers and Erasers of Histone H3</a></li> <li><a href="/pathways/atpdependent-chromatin-remodeling">ATP-dependent Chromatin Remodeling</a></li> <li><a href="/pathways/nuclear-receptors">Nuclear Receptors</a></li> </ul> </div> </div> <div class="accordionGroupHeading" role="tab" id="heading06"> <h3> <a role="button" data-toggle="collapse" href="#collapse06" aria-expanded="false" aria-controls="collapse06"> GPCR, Calcium, cAMP</a> </h3> </div> <div id="collapse06" class="collapse" role="tabpanel" aria-labelledby="heading06"> <div class="accordionGroupBody"> <p></p> <ul> <li><a href="/pathways/by-research/gpcr-calcium-camp-pathways">GPCR, Calcium, cAMP</a></li> <li><a href="/pathways/protein-kinase-c-signaling">Protein Kinase C Signaling</a></li> <li><a href="/pathways/phospholipase-signaling-pathway">Phospholipase Signaling</a></li> <li><a href="/pathways/receptors-signaling-to-mapk-erk">G-Protein-Coupled Receptors Signaling to MAPK/Erk</a></li> </ul> </div> </div> <div class="accordionGroupHeading" role="tab" id="heading07"> <h3> <a role="button" data-toggle="collapse" href="#collapse07" aria-expanded="false" aria-controls="collapse07"> Immunology/Inflammation</a> </h3> </div> <div id="collapse07" class="collapse" role="tabpanel" aria-labelledby="heading07"> <div class="accordionGroupBody"> <p></p> <ul> <li><a href="/pathways/by-research/immunology-inflammation-pathways">Immunology/Inflammation</a></li> <li><a href="/pathways/toll-like-receptor-signaling-pathway">Toll-Like Receptor Signaling</a></li> <li><a href="/pathways/jak-stat-il6-receptor-signaling">Jak/Stat: IL-6 Receptor Signaling</a></li> <li><a href="/pathways/t-cell-receptor-signaling">T Cell Receptor Signaling</a></li> <li><a href="/pathways/nfkb-signaling-pathway">NF-κB Signaling</a></li> <li><a href="/pathways/cell-intrinsic-innate-immunity-signaling">Cell Intrinsic Innate Immunity Signaling</a></li> <li><a href="/pathways/b-cell-receptor-signaling">B Cell Receptor Signaling</a></li> <li><a href="/pathways/inflammasome-signaling">Inflammasome Signaling</a></li> <li><a href="/pathways/immune-cell-markers-human">Human Immune Cell Marker Guide</a></li> <li><a href="/pathways/immune-cell-markers-mouse">Mouse Immune Cell Marker Guide</a></li> <li><a href="/pathways/immune-checkpoint-signaling-pathway">Checkpoint Signaling in the Tumor Microenvironment</a></li> <li><a href="/pathways/mechanisms-of-fibrosis-pathway">Mechanisms of Fibrosis</a></li> <li><a href="/pathways/car-signaling-networks">CAR Signaling Networks</a></li> <li><a href="/pathways/rheumatoid-arthritis">Rheumatoid Arthritis Pathogenesis</a></li> </ul> </div> </div> <div class="accordionGroupHeading" role="tab" id="heading08"> <h3> <a role="button" data-toggle="collapse" href="#collapse08" aria-expanded="false" aria-controls="collapse08"> Kinase Signaling</a> </h3> </div> <div id="collapse08" class="collapse" role="tabpanel" aria-labelledby="heading08"> <div class="accordionGroupBody"> <p></p> <ul> <li><a href="/pathways/by-research/kinase-signaling-pathways">Kinase Signaling</a></li> <li><a href="/pathways/erbb-her-signaling">ErbB / HER Signaling</a></li> <li><a href="/pathways/sapk-jnk-signaling-cascades">SAPK/JNK Signaling Cascades</a></li> <li><a href="/pathways/mapk-erk-in-growth-and-differentiation">MAPK/Erk in Growth and Differentiation</a></li> <li><a href="/pathways/receptors-signaling-to-mapk-erk">G-Protein-Coupled Receptors Signaling to MAPK/Erk</a></li> <li><a href="/pathways/p38-mapk-signaling">p38 MAPK Signaling</a></li> <li><a href="/pathways/ampk-signaling-pathway">AMPK Signaling</a></li> <li><a href="/pathways/mtor-signaling-pathway">mTOR Signaling</a></li> <li><a href="/pathways/pathways-akt-signaling">PI3K/Akt Signaling</a></li> <li><a href="/pathways/phosphoinositide-lipid-signaling">Phosphoinositide (Lipid) Signaling Pathway</a></li> <li><a href="/pathways/protein-kinase-c-signaling">Protein Kinase C Signaling</a></li> <li><a href="/pathways/insulin-receptor-signaling-pathway">Insulin Receptor Signaling</a></li> <li><a href="/pathways/regulation-of-eif4e-and-p70-s6-kinase">Regulation of eIF4E and p70 S6 Kinase</a></li> <li><a href="/pathways/jak-stat-il6-receptor-signaling">Jak/Stat: IL-6 Receptor Signaling</a></li> </ul> </div> </div> <div class="accordionGroupHeading" role="tab" id="heading09"> <h3> <a role="button" data-toggle="collapse" href="#collapse09" aria-expanded="false" aria-controls="collapse09"> Neuroscience</a> </h3> </div> <div id="collapse09" class="collapse" role="tabpanel" aria-labelledby="heading09"> <div class="accordionGroupBody"> <p></p> <ul> <li><a href="/pathways/by-research/neuroscience-pathways">Neuroscience</a></li> <li><a href="/pathways/receptors-signaling-to-mapk-erk">G-Protein-Coupled Receptors Signaling to MAPK/Erk</a></li> <li><a href="/pathways/trem2-signaling">TREM2 Signaling</a></li> <li><a href="/pathways/vesicle-trafficking-presynaptic-pathway">Vesicle Trafficking Presynaptic Signaling</a></li> <li><a href="/pathways/pathways-alz">Alzheimer's Disease Signaling</a></li> <li><a href="/pathways/genetics-of-alzheimers-disease">Genetics of Alzheimer’s Disease</a></li> <li><a href="/pathways/dopamine-signaling-in-parkinsons-disease">Dopamine Signaling in Parkinson's Disease</a></li> <li><a href="/pathways/neuronal-and-glial-cell-markers">Neuronal and Glial Cell Markers</a></li> <li><a href="/pathways/post-synaptic-signaling">Post-Synaptic Signaling</a></li> </ul> </div> </div> <div class="accordionGroupHeading" role="tab" id="heading010"> <h3> <a role="button" data-toggle="collapse" href="#collapse010" aria-expanded="false" aria-controls="collapse010"> PI3K/AKT/MAPK Signaling</a> </h3> </div> <div id="collapse010" class="collapse" role="tabpanel" aria-labelledby="heading010"> <div class="accordionGroupBody"> <p></p> <ul> <li><a href="/pathways/by-research/pi3k-akt-mapk-signaling-pathways">PI3K/AKT/MAPK Signaling</a></li> <li><a href="/pathways/pathways-akt-signaling">PI3K/Akt Signaling</a></li> <li><a href="/pathways/phosphoinositide-lipid-signaling">Phosphoinositide (Lipid) Signaling Pathway</a></li> <li><a href="/pathways/mapk-erk-in-growth-and-differentiation">MAPK/Erk in Growth and Differentiation</a></li> <li><a href="/pathways/p38-mapk-signaling">p38 MAPK Signaling</a></li> <li><a href="/pathways/receptors-signaling-to-mapk-erk">G-Protein-Coupled Receptors Signaling to MAPK/Erk</a></li> </ul> </div> </div> <div class="accordionGroupHeading" role="tab" id="heading011"> <h3> <a role="button" data-toggle="collapse" href="#collapse011" aria-expanded="false" aria-controls="collapse011"> RNA Regulation, Translational Control, and Protein Synthesis</a> </h3> </div> <div id="collapse011" class="collapse" role="tabpanel" 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