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It is a versatile molecule with a wide variety of practical applications such as medical, dentistry, veterinary, food, and agrochemicals, among others. Its pharmacological applications have been the most investigated and reported, focusing on its prominent antimicrobial, antioxidant, anti-inflammatory, cicatrizing activities. Furthermore, it is noteworthy that the research on its agricultural applications has increased, highlighting its uses as a natural agrochemical and preservative to safeguard foods from pathogenic microorganisms both in sowing and storage, which could have a beneficial effect on human health and the environment. Research has also been reported on its activity as an insecticide, acaricide, and animal repellent. This review summarizes important aspects of thymol such as its bioavailability, synthesis, and biological activities, with special interest in practical applications." xml:lang="es" /> <meta name="DC.format" content="application/pdf" xml:lang="es" /> <meta name="DC.language" content="eng" xml:lang="es" scheme="DCTERMS.RFC1766" /> <meta name="DC.publisher" content="Elsevier" xml:lang="es" /> <meta name="DC.rights" content="info:eu-repo/semantics/openAccess" xml:lang="*" /> <meta name="DC.rights" content="https://creativecommons.org/licenses/by-nc-nd/2.5/ar/" xml:lang="*" scheme="DCTERMS.URI" /> <meta name="DC.subject" content="BIOACTIVITY" xml:lang="es" /> <meta name="DC.subject" content="MECHANISM OF ACTION" xml:lang="es" /> <meta name="DC.subject" content="SYNTHESIS" xml:lang="es" /> <meta name="DC.subject" content="THYMOL" xml:lang="es" /> <meta name="DC.subject" content="Química Orgánica" xml:lang="es" /> <meta name="DC.subject" content="Ciencias Químicas" xml:lang="es" /> <meta name="DC.subject" content="CIENCIAS NATURALES Y EXACTAS" xml:lang="es" /> <meta name="DC.title" content="Thymol bioactivity: A review focusing on practical applications" xml:lang="es" /> <meta name="DC.type" content="info:eu-repo/semantics/article" /> <meta name="DC.type" content="info:ar-repo/semantics/artículo" /> <meta name="DC.type" content="info:eu-repo/semantics/publishedVersion" /> <meta name="DC.date" content="2021-08-20T19:54:34Z" scheme="DCTERMS.W3CDTF" /> <meta name="DC.description" content="Fil: Escobar Caicedo, Angélica María. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Investigación y Desarrollo en Ciencias Aplicadas "Dr. Jorge J. Ronco". Universidad Nacional de la Plata. Facultad de Ciencias Exactas. Centro de Investigación y Desarrollo en Ciencias Aplicadas; Argentina" /> <meta name="DC.description" content="Fil: Perez, Miriam Cristina. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Centro de Investigaciones en Tecnología de Pinturas. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Investigaciones en Tecnología de Pinturas; Argentina" /> <meta name="DC.description" content="Fil: Romanelli, Gustavo Pablo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Investigación y Desarrollo en Ciencias Aplicadas "Dr. Jorge J. Ronco". Universidad Nacional de la Plata. Facultad de Ciencias Exactas. Centro de Investigación y Desarrollo en Ciencias Aplicadas; Argentina" /> <meta name="DC.description" content="Fil: Blustein, Guillermo. Provincia de Buenos Aires. Gobernación. Comisión de Investigaciones Científicas. Centro de Investigaciones en Tecnología de Pinturas. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Centro de Investigaciones en Tecnología de Pinturas; Argentina" /> <meta name="DC.identifier" content="CONICET Digital" /> <meta name="DC.identifier" content="CONICET" /> <meta name="DC.relation" content="info:eu-repo/semantics/altIdentifier/url/https://linkinghub.elsevier.com/retrieve/pii/S1878535220304561" /> <meta name="DC.relation" content="info:eu-repo/semantics/altIdentifier/doi/http://dx.doi.org/10.1016/j.arabjc.2020.11.009" /> <meta name="citation_doi" content="10.1016/j.arabjc.2020.11.009" /> <meta content="BIOACTIVITY; MECHANISM OF ACTION; SYNTHESIS; THYMOL; info:eu-repo/semantics/article; info:ar-repo/semantics/artículo; info:eu-repo/semantics/publishedVersion" name="citation_keywords" /> <meta content="Thymol bioactivity: A review focusing on practical applications" name="citation_title" /> <meta content="1878-5352" name="citation_issn" /> <meta content="Elsevier" name="citation_publisher" /> <meta content="eng" name="citation_language" /> <meta content="Escobar Caicedo, Angélica María" name="citation_author" /> <meta content="Perez, Miriam Cristina" name="citation_author" /> <meta content="Romanelli, Gustavo Pablo" name="citation_author" /> <meta content="Blustein, Guillermo" name="citation_author" /> <meta content="https://ri.conicet.gov.ar/bitstream/11336/139451/2/CONICET_Digital_Nro.5ce914b7-c61b-44c5-a136-4742b95517e9_A.pdf" name="citation_pdf_url" /> <meta content="2020-12" name="citation_date" /> <meta content="https://ri.conicet.gov.ar/handle/11336/139451" name="citation_abstract_html_url" /> <link rel="stylesheet" href="/themes/CONICETDigital/lib/css/style.css?v=1.01" media="all" type="text/css" /> <link rel="stylesheet" href="/static/css/autoptimize_859ecb60158b41ba29193deb026da47e.css?ver=1.2.2" media="all" type="text/css" /> <link rel="stylesheet" href="/static/css/autoptimize_859ecb60158b41ba29193deb026da47e.css?ver=1.2.2" media="all" type="text/css" /> <script src="/themes/CONICETDigital/lib/js/jquery.js?ver=1.12.4" type="text/javascript">;</script> <script src="/static/wp-includes/js/jquery/jquery-migrate.min.js?ver=1.4.1" type="text/javascript">;</script> <script src="/themes/CONICETDigital/lib/js/bootstrap.min.js?ver=5.0.4" type="text/javascript">;</script> <style> .ordenFecha select{ position: relative; 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} </script> <nav class="navbar fixed-left hidden-xs hidden-sm colIzqItem"> <script> window.onload = function() { var lis=jQuery(".colIzqItem li"); for(i=0;i <lis.length;i++){ jQuery(lis[i]).removeClass("active"); } jQuery(lis[0]).addClass("active"); } </script> <ul class="nav navbar-nav"> <li class="nav-item active"> <a href="#ds-main"> INFORMACIÓN GENERAL</a> </li> <li class="nav-item"> <a href="#anchorAbstract">RESUMEN</a> </li> <li class="nav-item"> <a href="/handle/11336/139451/statistics">ESTADISTICAS</a> </li> </ul> </nav> <div class="container-item site-content" id="content"> <div class="content-area-" id="primary"> <div class="imagenItem"> </div> <main style="max-width: 1214px" class="site-main-item" id="main"> <div class="row row-eq-height"> <div style="background-color: #f9f9f9;font-weight: 300;" class="col-md-12 col-sd-12 col-xs-12"> <div class="colItem"> <div data-target=".colIzqItem" data-spy="scroll"> <div id="aspect_artifactbrowser_ItemViewer_div_item-view" class="ds-static-div primary">  <div xmlns:oreatom="http://www.openarchives.org/ore/atom/" xmlns:ore="http://www.openarchives.org/ore/terms/" xmlns:atom="http://www.w3.org/2005/Atom" class="col-md-8 "> <div class="item-summary-view-metadata"> <span style="padding-left: 8px; background-color: #00BEE6; color: #fff; padding-right: 8px; padding-top:3px; padding-bottom:3px;font-weight: 500;"> Artículo</span> <h1 style="font-size:150%;font-weight: 500;font-family: 'Roboto'; margin-top: 3px;">Thymol bioactivity: A review focusing on practical applications</h1> <style>.noexiste{ color: #000; } .imagenItem{background-image: url('/static/images/item/CENFisica.jpg');} .imagenItem{background-image: url('/static/images/item/CENFisica.jpg');} </style> <div class="simple-item-view-authors"> <a style="text-decoration:none; font-weight: 400; " href="/author/49163">Escobar Caicedo, Angélica María<img src="/themes/CONICETDigital/images/conicet.png" alt="Icon" /> </a>; <a style="text-decoration:none; font-weight: 400; " href="/author/20602">Perez, Miriam Cristina<img src="/themes/CONICETDigital/images/conicet.png" alt="Icon" /> </a>; <a style="text-decoration:none; font-weight: 400; " href="/author/5890">Romanelli, Gustavo Pablo<img src="/themes/CONICETDigital/images/conicet.png" alt="Icon" /> </a>; <a style="text-decoration:none; font-weight: 400; " href="/author/2643">Blustein, Guillermo<img src="/themes/CONICETDigital/images/conicet.png" alt="Icon" /> </a> </div> <div class="simple-item-view-other"> <span class="bold">Fecha de publicación:</span> <span>12/2020</span> </div> <div class="simple-item-view-other"> <span class="bold">Editorial:</span> <span>Elsevier<br /> </span> </div> <div class="simple-item-view-other"> <span class="bold">Revista:</span> <span>Arabian Journal of Chemistry<br /> </span> </div> <div class="simple-item-view-other"> <span class="bold">ISSN:</span> <span>1878-5352<br /> </span> </div> <div class="simple-item-view-other"> <span class="bold">Idioma:</span> <span> Inglés <br /> </span> </div> <div class="simple-item-view-other"> <span class="bold">Tipo de recurso:</span> <span> Artículo publicado </span> </div> <div class="simple-item-view-description"> <span class="bold">Clasificación temática:</span> <div> <a href="/discover?filtertype=subjectClassification&filter_relational_operator=authority&filter=18">Química Orgánica</a> </div> </div> <div class="simple-item-view-description"> <h3 style=" font-size: 1.2em; color: #747474;" id="anchorAbstract">Resumen</h3> <div xmlns:i18n="http://apache.org/cocoon/i18n/2.1" style="overflow-wrap: break-word;">Thymol is a natural volatile monoterpenoid phenol that is the main active ingredient of oil extracted from species Thymus vulgaris L., commonly known as thyme, and other plants such as Ocimum gratissimum L., Origanum L., Carum copticum L., different species of the genus Satureja L., Oliveria decumbens Vent, and many others. It is a versatile molecule with a wide variety of practical applications such as medical, dentistry, veterinary, food, and agrochemicals, among others. Its pharmacological applications have been the most investigated and reported, focusing on its prominent antimicrobial, antioxidant, anti-inflammatory, cicatrizing activities. Furthermore, it is noteworthy that the research on its agricultural applications has increased, highlighting its uses as a natural agrochemical and preservative to safeguard foods from pathogenic microorganisms both in sowing and storage, which could have a beneficial effect on human health and the environment. Research has also been reported on its activity as an insecticide, acaricide, and animal repellent. This review summarizes important aspects of thymol such as its bioavailability, synthesis, and biological activities, with special interest in practical applications.</div> </div> <div class="simple-item-view-description"> <span class="bold">Palabras clave:</span> <span> <a href="
	 	/discover?filtertype=subject&filter_relational_operator=equals&filter=BIOACTIVITY">BIOACTIVITY , </a> <a href="
	 	/discover?filtertype=subject&filter_relational_operator=equals&filter=MECHANISM OF ACTION">MECHANISM OF ACTION , </a> <a href="
	 	/discover?filtertype=subject&filter_relational_operator=equals&filter=SYNTHESIS">SYNTHESIS , </a> <a href="
	 	/discover?filtertype=subject&filter_relational_operator=equals&filter=THYMOL">THYMOL</a> </span> </div> </div> <div> <span class="bold"> <a href="/handle/11336/139451?show=full"> Ver el registro completo </a> </span> </div> <div id="anchorComm"> </div> </div> <div xmlns:oreatom="http://www.openarchives.org/ore/atom/" xmlns:ore="http://www.openarchives.org/ore/terms/" xmlns:atom="http://www.w3.org/2005/Atom" class="col-md-4"> <div id="anchorFiles"> <div class="side-box-header">Archivos asociados</div> <div class="side-box-body"> <div style=" min-height: 160px;" class="row"> <div class="col-md-6 col-xs-6"> <a class="image-link" href="/bitstream/handle/11336/139451/CONICET_Digital_Nro.5ce914b7-c61b-44c5-a136-4742b95517e9_A.pdf?sequence=2&isAllowed=y" target="
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		 ">http://hdl.handle.net/11336/139451</a> </div> <div class="row"> <span class="bold col-md-1">URL:</span> <a class="col-md-10" target="_blank" href="https://linkinghub.elsevier.com/retrieve/pii/S1878535220304561" style="
		 font-weight: normal;
		 	">https://linkinghub.elsevier.com/retrieve/pii/S1878535220304561</a> </div> <div class="row"> <span class="bold col-md-1">DOI:</span> <a class="col-md-10" target="_blank" href="http://dx.doi.org/10.1016/j.arabjc.2020.11.009" style="
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		 	">http://dx.doi.org/10.1016/j.arabjc.2020.11.009</a> </div> </span> </div> <div class="side-box-header"> Colecciones </div> <div class="side-box-body"> <span> <div> <a href="
		 /handle/11336/132/discover
		 ">Articulos(CIDEPINT)</a> <br />Articulos de CENTRO DE INV EN TECNOLOGIA DE PINTURAS (I)</div> <div> <a href="
		 /handle/11336/136/discover
		 ">Articulos(CINDECA)</a> <br />Articulos de CENTRO DE INV EN CS.APLICADAS "DR.JORGE J.RONCO"</div> </span> </div> <div class="side-box-header"> Citación </div> <div class="side-box-body"> <span>Escobar Caicedo, Angélica María; Perez, Miriam Cristina; Romanelli, Gustavo Pablo; Blustein, Guillermo; Thymol bioactivity: A review focusing on practical applications; Elsevier; Arabian Journal of Chemistry; 13; 12; 12-2020; 9243-9269<br /> </span> </div> <div class="side-box-header"> Compartir </div> <div class="side-box-body"> <a title="Compartir en facebook" onclick="facebook()" href="#" class="btn_social"> <i style="color:#0695d6" class="fa fa-facebook"> <span /> </i> </a> <a title="Compartir en twitter" onclick="twitter()" class="btn_social"> <i style="color:#0695d6" class="fa fa-twitter-square"> <span /> </i> </a> <a title="Compartir en Linkedin" onclick="linkedin()" class="btn_social"> <i style="color:#0695d6" class="fa fa-linkedin-square"> <span /> </i> </a> <a title="Ver citas en google scholar" target="_blank" align="middle" id="googleScholar" class="btn_social googleScholar" href="
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