CINXE.COM
Human Phospho-STAT3 (S727) Antibody MAB4934: R&D Systems
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class="ds_title">Human Phospho-STAT3 (S727) Antibody </h1> <div class="dsSprite_rnd ds_brand_logo ds_rnd_logo"></div> </div> <div class="product_meta"> <span class="category_number">Catalog #: MAB4934</span> <br/> <span class="citations"> <a href="#product-citations" id="citation_count" class="jump_to" data-tab="3" data-tabname="product-citations"> 4 Citations </a> </span> <a href="/reviews/MAB4934" rel="nofollow"><span class="submit_review"><button class="btn btn-quaternary">Submit a Review</button></span></a> <span class="datasheet_link"> <a href="#product-datasheets">Datasheet / COA / SDS</a> </span> </div> <!--<div class="formulations_row row"> <div class="formulations_wrapper col-xs-12"> </div> </div>--> <div class="product_wrapper row"> <div class="product_ordering_wrapper col-xs-12 col-md-8 col-md-push-4"> <div class="product_ordering"> <form action="/products/human-phospho-stat3-s727-antibody-788335_mab4934" method="post" id="atc-datasheet-form" accept-charset="UTF-8"><div><div id="atc_datasheet_block"> <!-- Carrier Free Section --> <!-- Single Use Lyophilized Section --> <!-- Liquid Section --> <!-- Regular Products Section --> <table class="add_to_cart"> <thead> <tr> <th class="ds_catalog">Catalog #</th> <th class="ds_availability_column mobile-hide">Availability</th> <th class="ds_size_price_column">Size / Price</th> <th class="ds_quantity_column">Qty</th> </tr> </thead> <tbody> <tr class="et_atc_product" data-sku="MAB4934"> <td class="dat_catalog_column">MAB4934</td> <td class="et_atc_results" colspan="2"></td> <td class="ds_quantity ds_quantity_column"><div class="form-item form-item-catnum-mab4934 form-type-textfield form-group"><input class="atc_quantity atc_hidden atc_qty form-control form-text" placeholder="0" style="display:none;" type="text" id="edit-catnum-mab4934" name="catnum-MAB4934" value="" size="5" maxlength="3" /></div></td> </tr> <tr class="et_atc_product" data-sku="MAB4934-SP"> <td class="dat_catalog_column">MAB4934-SP</td> <td 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No. MAB4934 - Human Phospho-STAT3 (S727) Antibody" href="https://resources.rndsystems.com/images/datasheets/antibody/STAT3_MAB4934_Western_Blot_12408.jpg"> <img fetchpriority="high" src="https://resources.rndsystems.com/images/datasheets/antibody/STAT3_MAB4934_Western_Blot_12408.jpg" class="img-fluid" alt="Detection of Human Phospho-STAT3 (S727) by Western Blot." title="Detection of Human Phospho-STAT3 (S727) by Western Blot."> </a> <div class="search_image_other_count"> <span class="search_more_images">4 Images</span> </div> </div> </div> <div id="extra_images overview-images" class="hidden"> <a class="ds-image" data-toggle="lightbox" data-gallery="overview-images" data-footer="Detection of Phospho-STAT3 (S727) in IFN alpha-treated Daudi Human Cell Line by Flow Cytometry." data-title="Detection of Phospho-STAT3 (S727) in IFN alpha-treated Daudi Human Cell Line by Flow Cytometry." title="Cat. No. MAB4934 - Human Phospho-STAT3 (S727) Antibody" onClick="event.preventDefault();" href="https://resources.rndsystems.com/images/datasheets/antibody/STAT3_MAB4934_Flow_Cytometry_23565.jpg"> <img src="https://resources.rndsystems.com/images/datasheets/antibody/STAT3_MAB4934_Flow_Cytometry_23565.jpg" class="img-fluid" loading="lazy" alt="Detection of Phospho-STAT3 (S727) in IFN alpha-treated Daudi Human Cell Line by Flow Cytometry." title="Detection of Phospho-STAT3 (S727) in IFN alpha-treated Daudi Human Cell Line by Flow Cytometry."> </a> <a class="ds-image" data-toggle="lightbox" data-gallery="overview-images" data-footer="Detection of Human STAT3 by Western Blot" data-title="Detection of Human STAT3 by Western Blot" title="Cat. No. MAB4934 - Human Phospho-STAT3 (S727) Antibody" onClick="event.preventDefault();" href="https://resources.rndsystems.com/images/datasheets/mab4934_human-phospho-stat3-s727-mab-clone-788335-41202412505399.jpg"> <img src="https://resources.rndsystems.com/images/datasheets/mab4934_human-phospho-stat3-s727-mab-clone-788335-41202412505399.jpg" class="img-fluid" loading="lazy" alt="Detection of Human STAT3 by Western Blot" title="Detection of Human STAT3 by Western Blot"> </a> <a class="ds-image" data-toggle="lightbox" data-gallery="overview-images" data-footer="Detection of Human STAT3 by Western Blot" data-title="Detection of Human STAT3 by Western Blot" title="Cat. No. MAB4934 - Human Phospho-STAT3 (S727) Antibody" onClick="event.preventDefault();" href="https://resources.rndsystems.com/images/datasheets/mab4934_human-phospho-stat3-s727-mab-clone-788335-4120241252116.jpg"> <img src="https://resources.rndsystems.com/images/datasheets/mab4934_human-phospho-stat3-s727-mab-clone-788335-4120241252116.jpg" class="img-fluid" loading="lazy" alt="Detection of Human STAT3 by Western Blot" title="Detection of Human STAT3 by Western Blot"> </a> </div> </div> <div class="product_info_wrapper"> </div> <div id="view-more-target" class="datasheet_section_element"> <a href="/target/stat3?category=Primary Antibodies" class="btn btn-secondary">All STAT3 Antibodies</a> </div> </div> <div class="tabbed_content" id="rnd_antibody"> <div id="ds_tabs" class="tab_menu"> <div class="tab tab_1 tab_open" data-tab="1" data-tabname="product-details" id="dsTabs_product-details"> <span>Product Details</span> </div> <div class="tab tab_3" data-tab="3" data-tabname="product-citations" id="dsTabs_product-citations"> <span>Citations (4)</span> </div> <div class="tab tab_4" data-tab="4" data-tabname="faqs" id="dsTabs_faqs"> <span>FAQs</span> </div> <div class="tab tab_5" data-tab="5" data-tabname="supplemental-products" id="dsTabs_supplemental-products"> <span>Supplemental Products</span> </div> <div class="tab tab_6" data-tab="6" data-tabname="product-reviews" id="dsTabs_product-reviews"> <span> Reviews </span> </div> </div> <div class="tab_content tab_1 tab_open" data-tab="1" data-tabname="product-details" id="product-details"> <div class="datasheet_section_element"> <a class="btn btn-quaternary scroll_to anchor-link" href="#ds_summary" id="product-anchor-ds_summary">Summary</a> <a class="btn btn-quaternary scroll_to anchor-link" href="#ds_data_examples" id="product-anchor-ds_data_examples">Data Examples</a> <a class="btn btn-quaternary scroll_to anchor-link" href="#ds_preparation_storage" id="product-anchor-ds_preparation_storage">Preparation and Storage</a> <a class="btn btn-quaternary scroll_to anchor-link" href="#ds_calculator" id="product-anchor-ds_calculator">Reconstitution Calculator</a> <a class="btn btn-quaternary scroll_to anchor-link" href="#ds_background" id="product-anchor-ds_background">Background</a> <a class="btn btn-quaternary scroll_to anchor-link" href="#ds_datasheets" id="product-anchor-ds_datasheets">Product Datasheets</a> <a class="btn btn-quaternary scroll_to anchor-link" href="#ds_related_research_areas" id="product-anchor-ds_related_research_areas">Related Research Areas</a> </div> <h2 id="ds_summary">Human Phospho-STAT3 (S727) Antibody Summary</h2> <div class="datasheet_section"> <div class="ds_table summary_table"> <div class="ds_table_body"> <!-- Merging fb_description into details_list to use it keys as the label for the row. --> <div class="ds_table_row"> <div class="ds_table_cell summary_table_name">Species Reactivity</div> <div class="ds_table_cell summary_table_data"> Human </div> </div> <div class="ds_table_row"> <div class="ds_table_cell summary_table_name">Specificity</div> <div class="ds_table_cell summary_table_data"> Detects human STAT3 when phosphorylated at S727. </div> </div> <div class="ds_table_row"> <div class="ds_table_cell summary_table_name">Source</div> <div class="ds_table_cell summary_table_data"> Monoclonal Mouse IgG<sub>2B</sub> Clone # 788335 </div> </div> <div class="ds_table_row"> <div class="ds_table_cell summary_table_name">Purification</div> <div class="ds_table_cell summary_table_data"> Protein A or G purified from hybridoma culture supernatant </div> </div> <div class="ds_table_row"> <div class="ds_table_cell summary_table_name">Immunogen</div> <div class="ds_table_cell summary_table_data"> Phosphopeptide containing the human STAT3 S727 site </div> </div> <div class="ds_table_row"> <div class="ds_table_cell summary_table_name">Formulation</div> <div class="ds_table_cell summary_table_data"> Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS. </div> </div> <div class="ds_table_row"> <div class="ds_table_cell summary_table_name">Label</div> <div class="ds_table_cell summary_table_data"> Unconjugated </div> </div> </div> </div> </div> <div id="customer_also_purchased_block" class="loader" data-catalogId="MAB4934"></div> <div id="ds_applications" class="datasheet_section"> <h2>Applications</h2> <div class="ds_table app_table"> <div class="ds_table_head"> <div class="ds_table_head_row"> <div class="ds_table_head_cell app_table_blank"></div> <div class="ds_table_head_cell app_table_rec_conc">Recommended Concentration</div> <div class="ds_table_head_cell app_table_sample">Sample</div> </div> </div> <div class="ds_table_body"> <div class="ds_table_row"> <div class="ds_table_cell app_table_name">Western Blot</div> <div class="ds_table_cell app_table_dilution">1 µg/mL</div> <div class="ds_table_cell app_table_sample">See below</div> </div> <div class="ds_table_row"> <div class="ds_table_cell app_table_name">Intracellular Staining by Flow Cytometry</div> <div class="ds_table_cell app_table_dilution">0.25 µg/10<sup>6</sup> cells</div> <div class="ds_table_cell app_table_sample">See below</div> </div> </div> </div> <p>Please Note: Optimal dilutions should be determined by each laboratory for each application. <a href="/resources/protocols-troubleshooting-guides">General Protocols</a> are available in the Technical Information section on our website. </p> </div> <div id="ds_scientific_data" class="datasheet_section"> <div id="ds_data_examples"> <h2>Scientific Data</h2> <div id="data_examples"> <div class="row data_ex_row"> <a id="ds_image_0" class="pageAnchor"></a> <div class="data_ex_image_wrapper col-xs-12 col-sm-5 col-md-4"> <div class="data_ex_image"> <span class="data_ex_image_label"> Western Blot </span> <a class="ds-image overview-images data_ex_image_link" data-toggle="lightbox" data-gallery="overview-images-0" data-title="Detection of Human Phospho-STAT3 (S727) by Western Blot." data-footer="Detection of Human Phospho-STAT3 (S727) antibody by Western Blot." title="Cat. No. MAB4934 - Detection of Human Phospho-STAT3 (S727) antibody by Western Blot." href="https://resources.rndsystems.com/images/datasheets/antibody/STAT3_MAB4934_Western_Blot_12408.jpg"> <img loading="lazy" src="https://resources.rndsystems.com/images/datasheets/antibody/STAT3_MAB4934_Western_Blot_12408.jpg" class="img-fluid" alt="Detection of Human Phospho-STAT3 (S727) antibody by Western Blot." title="Detection of Human Phospho-STAT3 (S727) antibody by Western Blot."> <span class="data_ex_image_larger">View Larger</span> </a> </div> </div> <div class="data_ex_description col-xs-12 col-sm-7 col-md-8"> <p> <span class="data_ex_description_title">Detection of Human Phospho-STAT3 (S727) by Western Blot.</span> Western blot shows lysates of HepG2 human hepatocellular carcinoma cell line untreated (-) or treated (+) with 100 ng/mL Recombinant Human IL-6 (Catalog # <a class="NoLineLink" href="https://www.rndsystems.com/products/recombinant-human-il-6-protein_206-il">206-IL</a>) for 15 minutes. PVDF membrane was probed with 1 µg/mL of Mouse Anti-Human Phospho-STAT3 (S727) Monoclonal Antibody (Catalog # MAB4934) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # <a class="NoLineLink" href="https://www.rndsystems.com/products/mouse-igg-hrp-conjugated-antibody_haf018">HAF018</a>). A specific band was detected for Phospho-STAT3 (S727) at approximately 95 kDa (as indicated). This experiment was conducted under reducing conditions and using <a class="NoLineLink" href="https://www.rndsystems.com/resources/technical/western-blot-conditions">Immunoblot Buffer Group 1</a>. </p> </div> </div> <div class="row data_ex_row"> <a id="ds_image_1" class="pageAnchor"></a> <div class="data_ex_image_wrapper col-xs-12 col-sm-5 col-md-4"> <div class="data_ex_image"> <span class="data_ex_image_label"> Intracellular Staining by Flow Cytometry </span> <a class="ds-image overview-images data_ex_image_link" data-toggle="lightbox" data-gallery="overview-images-1" data-title="Detection of Phospho-STAT3 (S727) in IFN alpha-treated Daudi Human Cell Line by Flow Cytometry." data-footer="Detection of Phospho-STAT3 (S727) antibody in IFN alpha-treated Daudi Human Cell Line antibody by Flow Cytometry." title="Cat. No. MAB4934 - Detection of Phospho-STAT3 (S727) antibody in IFN alpha-treated Daudi Human Cell Line antibody by Flow Cytometry." href="https://resources.rndsystems.com/images/datasheets/antibody/STAT3_MAB4934_Flow_Cytometry_23565.jpg"> <img loading="lazy" src="https://resources.rndsystems.com/images/datasheets/antibody/STAT3_MAB4934_Flow_Cytometry_23565.jpg" class="img-fluid" alt="Detection of Phospho-STAT3 (S727) antibody in IFN alpha-treated Daudi Human Cell Line antibody by Flow Cytometry." title="Detection of Phospho-STAT3 (S727) antibody in IFN alpha-treated Daudi Human Cell Line antibody by Flow Cytometry."> <span class="data_ex_image_larger">View Larger</span> </a> </div> </div> <div class="data_ex_description col-xs-12 col-sm-7 col-md-8"> <p> <span class="data_ex_description_title">Detection of Phospho-STAT3 (S727) in IFN alpha-treated Daudi Human Cell Line by Flow Cytometry.</span> Daudi human Burkitt's lymphoma cell line was unstimulated (open histogram) or treated with 500 U/mL rhIFN-alpha for 20 minutes (filled histogram) and stained with Mouse anti-Human Phospho-STAT3 (S727) Molyclonal Antibody (Catalog # MAB4934) followed by APC-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # <a class="NoLineLink" href="https://www.rndsystems.com/products/mouse-f-ab-2-igg-h-l-apc-conjugated-antibody_f0101b">F0101B</a>). To facilitate intracellular staining, cells were fixed with paraformaldehyde and permeabilized with methanol. View our protocol for <a class="NoLineLink" href="https://www.rndsystems.com/literature_flow_cytometry_detergents.aspx">Staining Intracellular Molecules</a>. </p> </div> </div> <div class="row data_ex_row"> <a id="ds_image_2" class="pageAnchor"></a> <div class="data_ex_image_wrapper col-xs-12 col-sm-5 col-md-4"> <div class="data_ex_image"> <span class="data_ex_image_label"> Western Blot </span> <a class="ds-image overview-images data_ex_image_link" data-toggle="lightbox" data-gallery="overview-images-2" data-title="Detection of Human STAT3 by Western Blot" data-footer="Detection of Human STAT3 by Western Blot" title="Cat. No. MAB4934 - Detection of Human STAT3 by Western Blot" href="https://resources.rndsystems.com/images/datasheets/mab4934_human-phospho-stat3-s727-mab-clone-788335-41202412505399.jpg"> <img loading="lazy" src="https://resources.rndsystems.com/images/datasheets/mab4934_human-phospho-stat3-s727-mab-clone-788335-41202412505399.jpg" class="img-fluid" alt="Detection of Human STAT3 by Western Blot" title="Detection of Human STAT3 by Western Blot"> <span class="data_ex_image_larger">View Larger</span> </a> </div> </div> <div class="data_ex_description col-xs-12 col-sm-7 col-md-8"> <p> <span class="data_ex_description_title">Detection of Human STAT3 by Western Blot</span> Regulation of hepcidin by IL-10 in primary macrophages, showing (a) the effect of IL-10 on Hepcidin mRNA synthesis with and without anti-IL-10 blocking antibody; (b) Western blot of STAT3 phosphorylation 20 minutes after exposure to increasing concentrations of IL-10; (c) STAT3-P inhibition of IL-10 (30 ng/mL) by Stattic.Bar plots show data from at least 3 independent experiments and the sho Western blot shows data from a representative experiment. M = media, iso ctrl = isotype control. * P<0.05, ***P<0.01 (Mann-Whitney test, compared with Media control). Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/24520384), licensed under a CC-BY license. Not internally tested by R&D Systems. </p> </div> </div> <div class="row data_ex_row"> <a id="ds_image_3" class="pageAnchor"></a> <div class="data_ex_image_wrapper col-xs-12 col-sm-5 col-md-4"> <div class="data_ex_image"> <span class="data_ex_image_label"> Western Blot </span> <a class="ds-image overview-images data_ex_image_link" data-toggle="lightbox" data-gallery="overview-images-3" data-title="Detection of Human STAT3 by Western Blot" data-footer="Detection of Human STAT3 by Western Blot" title="Cat. No. MAB4934 - Detection of Human STAT3 by Western Blot" href="https://resources.rndsystems.com/images/datasheets/mab4934_human-phospho-stat3-s727-mab-clone-788335-4120241252116.jpg"> <img loading="lazy" src="https://resources.rndsystems.com/images/datasheets/mab4934_human-phospho-stat3-s727-mab-clone-788335-4120241252116.jpg" class="img-fluid" alt="Detection of Human STAT3 by Western Blot" title="Detection of Human STAT3 by Western Blot"> <span class="data_ex_image_larger">View Larger</span> </a> </div> </div> <div class="data_ex_description col-xs-12 col-sm-7 col-md-8"> <p> <span class="data_ex_description_title">Detection of Human STAT3 by Western Blot</span> Regulation of hepcidin by IL-10 in primary macrophages, showing (a) the effect of IL-10 on Hepcidin mRNA synthesis with and without anti-IL-10 blocking antibody; (b) Western blot of STAT3 phosphorylation 20 minutes after exposure to increasing concentrations of IL-10; (c) STAT3-P inhibition of IL-10 (30 ng/mL) by Stattic.Bar plots show data from at least 3 independent experiments and the sho Western blot shows data from a representative experiment. M = media, iso ctrl = isotype control. * P<0.05, ***P<0.01 (Mann-Whitney test, compared with Media control). Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/24520384), licensed under a CC-BY license. Not internally tested by R&D Systems. </p> </div> </div> </div> </div> </div> <div id="ds_calculator" class="datasheet_section"> <div id="btn_calculator_wrapper"><div class="datasheet_calculator_toggle btn btn-secondary" id="btn_reconstitution">Reconstitution Calculator</div></div><div id="datasheet_calculators"><div id="btn_reconstitution_calc" class="datasheet_calculator"><h2>Reconstitution Calculator</h2><div id="reconstitution_calculator" class="calculator"> <form id="recCalc"> <div class="reconstitution_calculator_text" id="reconstitution_calculator_instructions"> <p>The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.</p> </div> <div class="calc_section"> <label for="reconstitution_calculator_volume" class="calculator_label">Volume (to add to vial)</label> <input id="reconstitution_calculator_volume" name="reconstitution_calculator_volume" type="text" maxlength="16" placeholder="volume" class="calculator_input calculator_text"/> <span class="select_wrapper"> <select id="reconstitution_calculator_volume_unit" class="calculator_input calculator_select"> <option value="ml">ml</option> <option value="ul" selected="selected">ul</option> </select> </span> </div> <span class="calculator_equals calculator_operator">=</span> <div class="calc_section"> <label for="reconstitution_calculator_mass" class="calculator_label">Mass (in vial)</label> <input id="reconstitution_calculator_mass" name="reconstitution_calculator_mass" type="text" maxlength="16" placeholder="mass" class="calculator_input calculator_text"/> <span class="select_wrapper"> <select id="reconstitution_calculator_mass_unit" class="calculator_input calculator_select"> <option value="mg">mg</option> <option value="ug" selected="selected">ug</option> <option value="ng">ng</option> </select> </span> </div> <span class="calculator_divide calculator_operator">÷</span> <div class="calc_section"> <label for="reconstitution_calculator_concentration" class="calculator_label">Desired Reconstitution Concentration</label> <input id="reconstitution_calculator_concentration" name="reconstitution_calculator_concentration" type="text" maxlength="16" placeholder="conc." class="calculator_input calculator_text"/> <span class="select_wrapper"> <select id="reconstitution_calculator_concentration_unit" class="calculator_input calculator_select"> <option value="mg/ml">mg/ml</option> <option value="ug/ml" selected="selected">ug/ml</option> <option value="ng/ml">ng/ml</option> </select> </span> </div> <div id="reconstitution_foot" class="calc_section"> <input type="submit" value="Calculate" id="button_reconstitution_calculator_calculate" class="calculator_button btn btn-secondary"/> </div> </form> </div> </div></div> </div> <div id="ds_preparation_storage" class="datasheet_section"> <h2>Preparation and Storage</h2> <div class="ds_table prep_table"> <div class="ds_table_body"> <div class="ds_table_row"> <div class="ds_table_cell prep_table_name">Reconstitution</div> <div class="ds_table_cell prep_table_data">Sterile PBS to a final concentration of 0.5 mg/mL. <div id="reconstitution-buffer"> <div id="reconstitution-buffer-placeholder"> <div class="et_spinner_small"></div> Loading... </div> </div> </div> </div> <div class="ds_table_row"> <div class="ds_table_cell prep_table_name">Shipping</div> <div class="ds_table_cell prep_table_data">Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below. </div> </div> <div class="ds_table_row"> <div class="ds_table_cell prep_table_name">Stability & Storage</div> <div class="ds_table_cell prep_table_data"><b>Use a manual defrost freezer and avoid repeated freeze-thaw cycles. </b><UL><LI>12 months from date of receipt, -20 to -70 °C as supplied.</LI><LI>1 month, 2 to 8 °C under sterile conditions after reconstitution.</LI><LI>6 months, -20 to -70 °C under sterile conditions after reconstitution.</LI></UL> </div> </div> </div> </div> </div> <div id="ds_background" class="datasheet_section"> <h2>Background: STAT3</h2> <p>Signal Transducer and Activator of Transcription (STAT) proteins are transcription factors activated in response to cytokine, growth factor, or hormone receptor signaling. Janus kinases (JAKs) phosphorylate STAT proteins and induce dimerization. Homo- or heterodimers translocate to the nucleus where they bind to DNA and activate transcription.</p> <div class="ds_table background_table"> <div class="ds_table_body"> <div class="ds_table_row"> <div class="ds_table_cell background_table_name">Long Name</div> <div class="ds_table_cell background_table_data">Signal Transducer and Activator of Transcription 3</div> </div> <div class="ds_table_row"> <div class="ds_table_cell background_table_name">Entrez Gene IDs</div> <div class="ds_table_cell background_table_data">6774 (Human); 20848 (Mouse); 25125 (Rat)</div> </div> <div class="ds_table_row"> <div class="ds_table_cell background_table_name">Alternate Names</div> <div class="ds_table_cell background_table_data">Acute-phase response factor; APRFMGC16063; DNA-binding protein APRF; FLJ20882; HIES; signal transducer and activator of transcription 3 (acute-phase responsefactor); signal transducer and activator of transcription 3; STAT3</div> </div> </div> </div> </div> <div class="datasheet_section" id="product-datasheets"> <h2 id="ds_datasheets">Product Datasheets</h2> <div class="product_datasheets"> <span class="sds-message hide"> <p class="sds-label">You must select a language.</p> <span class="close_sds_message">x</span> </span> <div class="ds_document"> <a id="cfpdf" href="//resources.rndsystems.com/pdfs/datasheets/mab4934.pdf?v=20241130" class="datasheets-link " target="_blank" rel="noreferrer nofollow">Product Datasheet</a> </div> <div class="ds_document"> <div class="ds_pdfData"><a class="datasheets-link" href="https://www.rndsystems.com/cofas/human-phospho-stat3-s727-antibody-788335_mab4934">COA</a> </div> </div> <div class="ds_document sds_link"> <a class="sds_non_cf datasheets-link non_cf_download_link" target="_blank" rel="noreferrer" data-path="//aero.bio-techne.com/sds/pdf/mab4934?v=20241130">SDS</a> </div> </div> </div> <div id="ds_related_research_areas" class="datasheet_section"> <h2>Related Research Areas</h2> <ul class="ds_details"> <li> <a href="/research-area/apoptosis-transcription-factors-and-regulators">Apoptosis Transcription Factors and Regulators</a> </li> <li> <a href="/research-area/b-cell-markers">B Cell Markers</a> </li> <li> <a href="/research-area/cancer-stem-cell-transcription-factors">Cancer Stem Cell Transcription Factors</a> </li> <li> <a href="/research-area/chemokine-receptor-intracellular-signaling">Chemokine Receptor Intracellular Signaling</a> </li> <li> <a href="/research-area/common-gamma-chain-receptor-family">Common gamma Chain Receptor Family</a> </li> <li> <a href="/research-area/dendritic-cell-development">Dendritic Cell Development</a> </li> <li> <a href="/research-area/embryonic-and-induced-pluripotent-stem-cell-markers">Embryonic and Induced Pluripotent Stem Cell Markers</a> </li> <li> <a href="/research-area/epithelial-stem-cell-transcription-factors">Epithelial Stem Cell Transcription Factors</a> </li> <li> <a href="/research-area/focal-adhesions">Focal Adhesions</a> </li> <li> <a href="/research-area/gametes-and-fertilization">Gametes and Fertilization</a> </li> <li> <a href="/research-area/gdnf-family">GDNF Family</a> </li> <li> <a href="/research-area/hematopoietic-stem-cell-transcription-factors-and-regulators">Hematopoietic Stem Cell Transcription Factors and Regulators</a> </li> <li> <a href="/research-area/il--10-and-interferon-family-regulators">IL-10 and Interferon Family Regulators</a> </li> <li> <a href="/research-area/il--10-family">IL-10 Family</a> </li> <li> <a href="/research-area/il--12-family">IL-12 Family</a> </li> <li> <a href="/research-area/immunoglobulin--like-domain-transcription-factors">Immunoglobulin-Like Domain Transcription Factors</a> </li> <li> <a href="/research-area/interferons">Interferons</a> </li> <li> <a href="/research-area/intracellular-signaling-molecules-in-angiogenesis">Intracellular Signaling Molecules in Angiogenesis</a> </li> <li> <a href="/research-area/jak-and-stat-proteins">Jak and STAT Proteins</a> </li> <li> <a 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href="/research-area/transcription-factors-in-the-akt-pathway">Transcription Factors in the Akt Pathway</a> </li> <li> <a href="/research-area/transcriptional-regulators-in-allergy-and-asthma">Transcriptional Regulators in Allergy and Asthma</a> </li> <li> <a href="/research-area/vegf-family">VEGF Family</a> </li> </ul> </div> </div> <div class="tab_content tab_3" data-tab="3" data-tabname="product-citations" id="citations"> <a id="citations_section"></a> <h2><span class="citations">Citations for Human Phospho-STAT3 (S727) Antibody</h2> <div id="citation"> <a id="dsTabCitations"></a> <p> R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. </p> <p> <strong><span id="maxcitations">4</span> Citations: Showing <span id="showfrom">1</span> - <span id="showto">4</span> </strong> <br/><strong>Filter your results:</strong> </p> <div class="row"> <div class="col-sm-12"> <div class="citations_filters"> <p style="display:inline;"><b>Filter by:</b></p> <div class="select_wrapper filter_select"> <select id="selSpecies" title="Species"> <option value="All">All Species</option> <option class="citation_filterRadio" value="species" data-filter="Human"> Human </option> <option class="citation_filterRadio" value="species" data-filter="Mouse"> Mouse </option> </select> </div> <div class="select_wrapper filter_select"> <select id="selAntibody" title="Applications"> <option value="All">All Applications</option> <option class="citation_filterRadio" value="application" data-filter="Western Blot"> Western Blot </option> </select> </div> <div class="select_wrapper filter_select"> <select id="selSampleType" title="Sample Types"> <option value="All">All Sample Types</option> <option class="citation_filterRadio" value="sampletype" data-filter="Cell Lysates"> Cell Lysates </option> </select> </div> </div> </div> </div> <div class="row"> <ol id="citations" class="col-xs-12" data-expandall="false" data-max-citations="4" data-max-show="10"> <li class="top-lined" data-species="Human" data-application="Western Blot" data-sampletype="Cell Lysates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/37055381"> Galectin-3 promotes secretion of proteases that decrease epithelium integrity in human colon cancer cells </a> </span><br/> Authors: S Li, DM Pritchard, LG Yu<br/> Cell Death & Disease, 2023-04-13;14(4):268.<br/> Species: Human<br/> Sample Types: Cell Lysates<br/> Applications: Western Blot </li> <li class="top-lined" data-species="Mouse" data-application="Western Blot" data-sampletype="Cell Lysates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/35684106"> Piceatannol, a Dietary Polyphenol, Alleviates Adipose Tissue Loss in Pre-Clinical Model of Cancer-Associated Cachexia via Lipolysis Inhibition </a> </span><br/> Authors: JC Kershaw, BD Elzey, XX Guo, KH Kim<br/> Nutrients, 2022-05-31;14(11):.<br/> Species: Mouse<br/> Sample Types: Cell Lysates<br/> Applications: Western Blot </li> <li class="top-lined" data-species="Human" data-application="Western Blot" data-sampletype="Cell Lysates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/24520384"> Interleukin-10 regulates hepcidin in Plasmodium falciparum malaria. </a> </span><br/> Authors: Huang H, Lamikanra A, Alkaitis M, Thezenas M, Ramaprasad A, Moussa E, Roberts D, Casals-Pascual C<br/> PLoS ONE, 2014-02-10;9(2):e88408.<br/> Species: Human<br/> Sample Types: Cell Lysates<br/> Applications: Western Blot </li> <li class="top-lined" data-species="" data-application="" data-sampletype=""> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/33065253"> Demonstration of intracellular trafficking, cytosolic bioavailability, and target manipulation of an antibody delivery platform </a> </span><br/> Authors: Wei Lv, Julie A. 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