Innovative CAR T Therapy | PEGS Europe

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The generation of chimeric antigen receptor (CAR) T cells <i>in vivo</i> can be achieved by delivering mRNA in T cell-targeted lipid nanoparticles (LNPs) and in vivo programming. This exciting area will be featured at in the Innovative CAR T Therapy conference at PEGS Europe and will review innovative CAR structures, gene-editing tools, and gene delivery techniques to help design and develop new CAR constructs and engineer therapies in vivo. Various approaches and technologies will be assessed for their immunogenicity, potency, and modes of CAR delivery, both permanent and transient. This conference will examine what it will take to transform new CAR constructs and <i>in vivo</i> CAR therapy from proof-of-concept to a robust technology for clinical use.</p><p><b>Scientific Advisory Board: </b></p><div><b>Melita Irving</b>, PhD, Group Leader, Ludwig Institute for Cancer Research, University of Lausanne </div><div><b>Astero Klampatsa</b>, PhD, Team Leader, Cancer Therapeutics, Institute of Cancer Research</div><p><b></b><b></b></p></div> </div> <div > <div class="sf-Long-text" ><div style="margin-top: 5px;" class="TextBlock schTextBlock Shaded"> <p><b>Recommended Short Course*</b><br /> <b>Monday, 4 November, 14:00 – 17:00</b><br /> <b>SC6: Introduction to Immunogenicity of Biotherapeutics</b><br /> <i>*Separate registration required. See <a href="/short-courses#6" data-sf-ec-immutable="">short courses page</a> for details. 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Innovative CAR T Therapy | PEGS Europe | 5-7 November 2024