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<meta property='og:description' content='Overview A UK-based lab that provides genomic testing for infectious diseases worked with Automata to take its lab automation to the next level by automating the bottleneck in their workflow. Automata’s solution will result in a significant reduction in manual interactions, allowing staff to focus on other activities. 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.wiki-anchor-links--wrapper ul li { list-style: none; } /* twa-list-none doesn't work for some reason. Temporarily implemented */ </style> <ul class="md:twa-pt-7.5 md:twa-pr-7.5 md:twa-list-none"> <li class="anchor-link has-p-body-font-size twa-pb-7.5 md:twa-pb-0 md:twa-bg-blockquote twa-cursor-pointer md:hover:twa-bg-pink-500 md:hover:twa-text-white md:twa-mb-5" data-anchor-id="h-overview"><button class="md:twa-px-5 md:twa-py-4 twa-text-left twa-w-full twa-underline md:twa-no-underline" onclick="window.triggerAnchor(event);" role="button" title="Overview">Overview</button></li><li class="anchor-link has-p-body-font-size twa-pb-7.5 md:twa-pb-0 md:twa-bg-blockquote twa-cursor-pointer md:hover:twa-bg-pink-500 md:hover:twa-text-white md:twa-mb-5" data-anchor-id="h-the-brief"><button class="md:twa-px-5 md:twa-py-4 twa-text-left twa-w-full twa-underline md:twa-no-underline" onclick="window.triggerAnchor(event);" role="button" title="The brief">The brief</button></li><li class="anchor-link has-p-body-font-size twa-pb-7.5 md:twa-pb-0 md:twa-bg-blockquote twa-cursor-pointer md:hover:twa-bg-pink-500 md:hover:twa-text-white md:twa-mb-5" data-anchor-id="h-the-challenge"><button class="md:twa-px-5 md:twa-py-4 twa-text-left twa-w-full twa-underline md:twa-no-underline" onclick="window.triggerAnchor(event);" role="button" title="The challenge">The challenge</button></li><li class="anchor-link has-p-body-font-size twa-pb-7.5 md:twa-pb-0 md:twa-bg-blockquote twa-cursor-pointer md:hover:twa-bg-pink-500 md:hover:twa-text-white md:twa-mb-5" data-anchor-id="h-automata-s-solution"><button class="md:twa-px-5 md:twa-py-4 twa-text-left twa-w-full twa-underline md:twa-no-underline" onclick="window.triggerAnchor(event);" role="button" title="Automata's solution">Automata's solution</button></li><li class="anchor-link has-p-body-font-size twa-pb-7.5 md:twa-pb-0 md:twa-bg-blockquote twa-cursor-pointer md:hover:twa-bg-pink-500 md:hover:twa-text-white md:twa-mb-5" data-anchor-id="h-estimated-impact"><button class="md:twa-px-5 md:twa-py-4 twa-text-left twa-w-full twa-underline md:twa-no-underline" onclick="window.triggerAnchor(event);" role="button" title="Estimated impact">Estimated impact</button></li><li class="anchor-link has-p-body-font-size twa-pb-7.5 md:twa-pb-0 md:twa-bg-blockquote twa-cursor-pointer md:hover:twa-bg-pink-500 md:hover:twa-text-white md:twa-mb-5" data-anchor-id="h-download-the-full-case-study-for-free"><button class="md:twa-px-5 md:twa-py-4 twa-text-left twa-w-full twa-underline md:twa-no-underline" onclick="window.triggerAnchor(event);" role="button" title="Download the full case study for free">Download the full case study for free</button></li> </ul> </div> </div> </div> <div class="md:twa-pb-5 md:twa-pt-7.5 twa-bg-white twa-flex-col md:twa-flex-row twa-flex"> <div class='au-container--copy-narrow md:twa-mr-0 md:twa-pb-15'> <h2 class="wp-block-heading" id="h-overview">Overview</h2> <p>A UK-based lab that provides genomic testing for infectious diseases worked with Automata to take its lab automation to the next level by automating the bottleneck in their workflow. Automata’s solution will result in a significant reduction in manual interactions, allowing staff to focus on other activities.</p> <div style="height:60px" aria-hidden="true" class="wp-block-spacer"></div> <h2 class="wp-block-heading" id="h-the-brief">The brief</h2> <p>The lab had previously used <a href="https://automata.tech/applications/genomics/" class="ek-link">automated systems for their genomic testing workflow</a>. However, when they made the decision to reduce reagent costs by changing their DNA library preparation process to use 384-well microplates rather than 96-well microplates, they found that the existing system was not sufficiently flexible. </p> <p>Staff now had to manually move plates from one piece of equipment to another during library preparation, and this had a detrimental effect on both throughput and walkaway time. </p> <p>Automata was asked to provide an <a href="https://automata.tech/applications/genomics/automated-library-prep/" class="ek-link"><span style="text-decoration: underline;" class="ek-underline">automated library preparation system</span></a> capable of handling 384-well microplates, in order to streamline the genomic testing process and provide the capacity for upscaling.</p> <p>It was important that traceability was maintained for the whole process, and that this data was exported to LIMS.</p> <div style="height:60px" aria-hidden="true" class="wp-block-spacer"></div> <h2 class="wp-block-heading" id="h-the-challenge">The challenge</h2> <p>The current library preparation process required significant manual interaction throughout the day, and a key requirement was to fully automate the process, freeing up lab staff to work on more value-added activities.</p> <div style="height:60px" aria-hidden="true" class="wp-block-spacer"></div> <h2 class="wp-block-heading" id="h-automata-s-solution">Automata's solution</h2> <h3 class="wp-block-heading has-titles-font-size" id="h-automata-worked-with-the-lab-to-design-an-automated-dna-library-preparation-system-which-would-slot-in-between-their-existing-automated-processes">Automata worked with the lab to design an automated DNA library preparation system which would slot in-between their existing automated processes</h3> <p>Automata is a <a href="https://automata.tech/linq/">lab automation platform</a> that combines specialised lab benches with open, integrated orchestration software. This turns labour-intensive workflows into streamlined automated systems, providing true ‘walkaway’ time for staff. Automata’s solutions are achieved through combined robotic and digital integration of multiple devices, many of which a lab may already have.</p> <div style="height:24px" aria-hidden="true" class="wp-block-spacer"></div> <figure class="wp-block-image aligncenter size-full"><img alt="" data-src="https://automata.tech/wp-content/uploads/2023/03/Reducing-human-interaction-flow-1@3x.png" class="wp-image-6872 lazyload" src="data:image/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==" /><noscript><img src="https://automata.tech/wp-content/uploads/2023/03/Reducing-human-interaction-flow-1@3x.png" alt="" class="wp-image-6872"/></noscript></figure> <div style="height:24px" aria-hidden="true" class="wp-block-spacer"></div> <p>Built on the Automata LINQ <a href="https://automata.tech/linq/bench/">robotic lab bench</a>, the automated library preparation system could be expanded or adapted over time, with the addition of new lab equipment, or by adding further LINQ modules. </p> <p>Automata’s <a href="https://automata.tech/linq/cloud/">cloud-based laboratory orchestrator</a> was used to provide a software platform that seamlessly connected each activity in the library prep workflow, providing full traceability for each sample, and entering test data into the lab’s LIMS. </p> <p>With a piece of equipment able to operate concurrently, the lab was able to parallelise activity, maximising the capacity of each system.</p> <p>The following equipment was integrated into the system:</p> <ul class="wp-block-list"> <li>Microplate shaker</li> <li>Microplate vortex</li> <li>Microplate  reader</li> <li>Liquid handlers</li> <li>Magnetic bead separation block</li> <li>Cooling block</li> <li>Microplate incubator</li> <li>Microplate sealer</li> <li>Microplate peeler</li> <li>Microplate centrifuge</li> <li>Thermocycler</li> <li>Automata LINQ modules</li> <li>Automata Scara Robots</li> </ul> <figure class="wp-block-image aligncenter size-large"><img alt="" data-src="https://automata.tech/wp-content/uploads/2023/03/Reducing-human-interaction-Render-3_edited-1024x639.jpg" class="wp-image-6873 lazyload" src="data:image/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==" /><noscript><img src="https://automata.tech/wp-content/uploads/2023/03/Reducing-human-interaction-Render-3_edited-1024x639.jpg" alt="" class="wp-image-6873"/></noscript></figure> <div style="height:70px" aria-hidden="true" class="wp-block-spacer"></div> <div class="kb-row-layout-wrap kb-row-layout-id6864_184398-2c alignnone has-grey-50-background-color kt-row-has-bg wp-block-kadence-rowlayout"><div class="kt-row-column-wrap kt-has-2-columns kt-row-layout-equal kt-tab-layout-inherit kt-mobile-layout-row kt-row-valign-top"> <div class="wp-block-kadence-column kadence-column6864_512a4e-0d"><div class="kt-inside-inner-col"> <figure class="wp-block-kadence-image kb-image6864_8a0932-5e"><img alt="A dark image of the Automata LINQ bench that shows the name 'LINQ' on the front of it. There is a light blue LED light around the edge of the bench." data-src="https://automata.tech/wp-content/uploads/2024/11/AUTOMATA-LINQ-BENCH_DARK-2-edited.jpg" class="kb-img wp-image-16934 lazyload" src="data:image/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==" /><noscript><img src="https://automata.tech/wp-content/uploads/2024/11/AUTOMATA-LINQ-BENCH_DARK-2-edited.jpg" alt="A dark image of the Automata LINQ bench that shows the name 'LINQ' on the front of it. There is a light blue LED light around the edge of the bench." class="kb-img wp-image-16934"/></noscript></figure> </div></div> <div class="wp-block-kadence-column kadence-column6864_ab0031-5d"><div class="kt-inside-inner-col"> <h5 class="kt-adv-heading6864_fd8baa-5f wp-block-kadence-advancedheading has-primary-color has-text-color" data-kb-block="kb-adv-heading6864_fd8baa-5f">Ready to Scale Up Your Lab’s Efficiency?</h5> <p class="has-primary-color has-text-color has-link-color wp-elements-5b45bd7b61b291831f00d7039a1e5b05">Unlock seamless, scalable automation with LINQ, connecting instruments and workflows to adapt as your lab grows.</p> <div style="height:0px" aria-hidden="true" class="wp-block-spacer"></div> <div class="wp-block-kadence-column kadence-column6864_9f1aac-d1"><div class="kt-inside-inner-col"> <div class="wp-block-kadence-advancedbtn kb-buttons-wrap kb-btns6864_adaf4a-40"><a class="kb-button kt-button button kb-btn6864_1e5a4b-24 kt-btn-size-standard kt-btn-width-type-auto kb-btn-global-fill kt-btn-has-text-true kt-btn-has-svg-false wp-block-kadence-singlebtn" href="https://automata.tech/linq/"><span class="kt-btn-inner-text">Find Out More</span></a></div> </div></div> </div></div> </div></div> <div style="height:70px" aria-hidden="true" class="wp-block-spacer"></div> <h2 class="wp-block-heading" id="h-estimated-impact">Estimated impact</h2> <p>Based on the final solution that will be installed, the new, <a href="https://automata.tech/applications/genomics/automated-library-prep/">fully automated library preparation</a> process is expected to achieve:</p> <p>95% reduction in manual interaction</p> <p>Reduced risk of manual errors</p> <p>Increased data quality as all actions will be fully traceable</p> <figure class="wp-block-image aligncenter size-large"><img alt="" data-src="https://automata.tech/wp-content/uploads/2023/03/Reducing-human-interaction-reduction@3x-1024x342.png" class="wp-image-6874 lazyload" src="data:image/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==" /><noscript><img src="https://automata.tech/wp-content/uploads/2023/03/Reducing-human-interaction-reduction@3x-1024x342.png" alt="" class="wp-image-6874"/></noscript></figure> <p class="has-small-print-font-size">*The lab first engaged with Automata in Q3 of 2022, and the final system is due to be installed in Q3 of 2023, an end-to-end process of about one year.</p> <div style="height:60px" aria-hidden="true" class="wp-block-spacer"></div> <h2 class="wp-block-heading" id="h-download-the-full-case-study-for-free">Download the full case study for free</h2> <div class="wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex"> <div class="wp-block-button"><a class="wp-block-button__link wp-element-button" title="click here for your free download" href="https://automata.tech/wp-content/uploads/2023/02/Automata-genomics-reducing-manual-interactions-case-study.pdf" target="_blank" rel="noreferrer 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