Search results for: Keping Zuo

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Zuo</title> <meta name="description" content="Search results for: Keping Zuo"> <meta name="keywords" content="Keping Zuo"> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1, maximum-scale=1, user-scalable=no"> <meta charset="utf-8"> <link href="https://cdn.waset.org/favicon.ico" type="image/x-icon" rel="shortcut icon"> <link href="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/css/bootstrap.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/plugins/fontawesome/css/all.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/css/site.css?v=150220211555" rel="stylesheet"> </head> <body> <header> <div class="container"> <nav class="navbar navbar-expand-lg navbar-light"> <a class="navbar-brand" href="https://waset.org"> <img src="https://cdn.waset.org/static/images/wasetc.png" alt="Open Science Research Excellence" title="Open Science Research Excellence" /> </a> <button class="d-block d-lg-none navbar-toggler ml-auto" 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id="custom-search-input"> <div class="input-group"> <i class="fas fa-search"></i> <input type="text" class="search-query" name="q" placeholder="Author, Title, Abstract, Keywords" value="Keping Zuo"> <input type="submit" class="btn_search" value="Search"> </div> </div> </form> </div> </div> <div class="row mt-3"> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Commenced</strong> in January 2007</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Frequency:</strong> Monthly</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Edition:</strong> International</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Paper Count:</strong> 2</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: Keping Zuo</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2</span> The Effect of Stent Coating on the Stent Flexibility: Comparison of Covered Stent and Bare Metal Stent</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Keping%20Zuo">Keping Zuo</a>, <a href="https://publications.waset.org/abstracts/search?q=Foad%20Kabinejadian"> Foad Kabinejadian</a>, <a href="https://publications.waset.org/abstracts/search?q=Gideon%20Praveen%20Kumar%20Vijayakumar"> Gideon Praveen Kumar Vijayakumar</a>, <a href="https://publications.waset.org/abstracts/search?q=Fangsen%20Cui"> Fangsen Cui</a>, <a href="https://publications.waset.org/abstracts/search?q=Pei%20Ho"> Pei Ho</a>, <a href="https://publications.waset.org/abstracts/search?q=Hwa%20Liang%20Leo"> Hwa Liang Leo</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Carotid artery stenting (CAS) is the standard procedure for patients with severe carotid stenosis at high risk for carotid endarterectomy (CAE). A major drawback of CAS is the higher incidence of procedure-related stroke compared with traditional open surgical treatment for carotid stenosis - CEA, even with the use of the embolic protection devices (EPD). As the currently available bare metal stents cannot address this problem, our research group developed a novel preferential covered-stent for carotid artery aims to prevent friable fragments of atherosclerotic plaques from flowing into the cerebral circulation, and yet maintaining the flow of the external carotid artery. The preliminary animal studies have demonstrated the potential of this novel covered-stent design for the treatment of carotid atherosclerotic stenosis. The purpose of this study is to evaluate the effect of membrane coating on the stent flexibility in order to improve the clinical performance of our novel covered stents. A total of 21 stents were evaluated in this study: 15 self expanding bare nitinol stents and 6 PTFE-covered stents. 10 of the bare stents were coated with 11%, 16% and 22% Polyurethane(PU), 4%, 6.25% and 11% EE, as well as 22% PU plus 5 渭m Parylene. Different laser cutting designs were performed on 4 of the PTFE covert stents. All the stents, with or without the covered membrane, were subjected to a three-point flexural test. The stents were placed on two supports that are 30 mm apart, and the actuator is applying a force in the exact middle of the two supports with a loading pin with radius 2.5 mm. The loading pin displacement change, the force and the variation in stent shape were recorded for analysis. The flexibility of the stents was evaluated by the lumen area preservation at three displacement bending levels: 5mm, 7mm, and 10mm. All the lumen areas in all stents decreased with the increase of the displacement from 0 to 10 mm. The bare stents were able to maintain 0.864 卤 0.015, 0.740 卤 0.025 and 0.597 卤 0.031of original lumen area at 5 mm, 7 mm and 10mm displacement respectively. For covered stents, the stents with EE coating membrane showed the best lumen area preservation (0.839 卤 0.005, 0.7334 卤 0.043 and 0.559 卤 0.014), whereas, the stents with PU and Parylene coating were only 0.662, 0.439 and 0.305. Bending stiffness was also calculated and compared. These results provided optimal material information and it was crucial for enhancing clinical performance of our novel covered stents. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=carotid%20artery" title="carotid artery">carotid artery</a>, <a href="https://publications.waset.org/abstracts/search?q=covered%20stent" title=" covered stent"> covered stent</a>, <a href="https://publications.waset.org/abstracts/search?q=nonlinear" title=" nonlinear"> nonlinear</a>, <a href="https://publications.waset.org/abstracts/search?q=hyperelastic" title=" hyperelastic"> hyperelastic</a>, <a href="https://publications.waset.org/abstracts/search?q=stress" title=" stress"> stress</a>, <a href="https://publications.waset.org/abstracts/search?q=strain" title=" strain"> strain</a> </p> <a href="https://publications.waset.org/abstracts/41357/the-effect-of-stent-coating-on-the-stent-flexibility-comparison-of-covered-stent-and-bare-metal-stent" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/41357.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">295</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1</span> Polyurethane Membrane Mechanical Property Study for a Novel Carotid Covered Stent</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Keping%20Zuo">Keping Zuo</a>, <a href="https://publications.waset.org/abstracts/search?q=Jia%20Yin%20Chia"> Jia Yin Chia</a>, <a href="https://publications.waset.org/abstracts/search?q=Gideon%20Praveen%20Kumar%20Vijayakumar"> Gideon Praveen Kumar Vijayakumar</a>, <a href="https://publications.waset.org/abstracts/search?q=Foad%20Kabinejadian"> Foad Kabinejadian</a>, <a href="https://publications.waset.org/abstracts/search?q=Fangsen%20Cui"> Fangsen Cui</a>, <a href="https://publications.waset.org/abstracts/search?q=Pei%20Ho"> Pei Ho</a>, <a href="https://publications.waset.org/abstracts/search?q=Hwa%20Liang%20Leo"> Hwa Liang Leo</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Carotid artery is the major vessel supplying blood to the brain. Carotid artery stenosis is one of the three major causes of stroke and the stroke is the fourth leading cause of death and the first leading cause of disability in most developed countries. Although there is an increasing interest in carotid artery stenting for treatment of cervical carotid artery bifurcation therosclerotic disease, currently available bare metal stents cannot provide an adequate protection against the detachment of the plaque fragments over diseased carotid artery, which could result in the formation of micro-emboli and subsequent stroke. Our research group has recently developed a novel preferential covered-stent for carotid artery aims to prevent friable fragments of atherosclerotic plaques from flowing into the cerebral circulation, and yet retaining the ability to preserve the flow of the external carotid artery. The preliminary animal studies have demonstrated the potential of this novel covered-stent design for the treatment of carotid therosclerotic stenosis. The purpose of this study is to evaluate the biomechanical property of PU membrane of different concentration configurations in order to refine the stent coating technique and enhance the clinical performance of our novel carotid covered stent. Results from this study also provide necessary material property information crucial for accurate simulation analysis for our stents. Method: Medical grade Polyurethane (ChronoFlex AR) was used to prepare PU membrane specimens. Different PU membrane configurations were subjected to uniaxial test: 22%, 16%, and 11% PU solution were made by mixing the original solution with proper amount of the Dimethylacetamide (DMAC). The specimens were then immersed in physiological saline solution for 24 hours before test. All specimens were moistened with saline solution before mounting and subsequent uniaxial testing. The specimens were preconditioned by loading the PU membrane sample to a peak stress of 5.5 Mpa for 10 consecutive cycles at a rate of 50 mm/min. The specimens were then stretched to failure at the same loading rate. Result: The results showed that the stress-strain response curves of all PU membrane samples exhibited nonlinear characteristic. For the ultimate failure stress, 22% PU membrane was significantly higher than 16% (p<0.05). In general, our preliminary results showed that lower concentration PU membrane is stiffer than the higher concentration one. From the perspective of mechanical properties, 22% PU membrane is a better choice for the covered stent. Interestingly, the hyperelastic Ogden model is able to accurately capture the nonlinear, isotropic stress-strain behavior of PU membrane with R2 of 0.9977 卤 0.00172. This result will be useful for future biomechanical analysis of our stent designs and will play an important role for computational modeling of our covered stent fatigue study. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=carotid%20artery" title="carotid artery">carotid artery</a>, <a href="https://publications.waset.org/abstracts/search?q=covered%20stent" title=" covered stent"> covered stent</a>, <a href="https://publications.waset.org/abstracts/search?q=nonlinear" title=" nonlinear"> nonlinear</a>, <a href="https://publications.waset.org/abstracts/search?q=hyperelastic" title=" hyperelastic"> hyperelastic</a>, <a href="https://publications.waset.org/abstracts/search?q=stress" title=" stress"> stress</a>, <a href="https://publications.waset.org/abstracts/search?q=strain" title=" strain"> strain</a> </p> <a href="https://publications.waset.org/abstracts/41343/polyurethane-membrane-mechanical-property-study-for-a-novel-carotid-covered-stent" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/41343.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">310</span> </span> </div> </div> </div> </main> <footer> <div id="infolinks" class="pt-3 pb-2"> <div class="container"> <div style="background-color:#f5f5f5;" class="p-3"> <div class="row"> <div class="col-md-2"> <ul class="list-unstyled"> About <li><a href="https://waset.org/page/support">About Us</a></li> <li><a href="https://waset.org/page/support#legal-information">Legal</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/WASET-16th-foundational-anniversary.pdf">WASET celebrates its 16th foundational anniversary</a></li> </ul> </div> <div 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Search results for: Keping Zuo