Childhood Cancer - Cancer Currents Blog

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Topics include new treatments, issues facing childhood cancer survivors, and findings on the biology of cancer in children.</p> </div> </div> <div class="slot-item last-SI"> <div class="dynamic list has-images"> <ul> <div class="views-element-container"><div class="js-view-dom-id-feceb16a47df391351e28927afbc2e220d4f3c095be5f2475aa23eda948d7d34"> <div class="item-list"> <ul> <li> <li class="general-list-item general list-item"> <div class="list-item-image image container"> <a class="item-image image" href="/news-events/cancer-currents-blog/2024/pediatric-low-grade-glioma-tovorafenib-braf"> <img loading="lazy" src="/sites/g/files/xnrzdm211/files/styles/cgov_thumbnail/public/cgov_image/media_image/2024-05/occ-cc-tumor-open-access-image-edit-052024.png?h=1e6eb8d0&itok=UHQxEA6i" width="228" height="171" alt="An MRI scan showing a side view of a child with a low-grade glioma in the lower back of the brain. " /> </a> </div> <div class="title-and-desc title desc container"> <a class="title" href="/news-events/cancer-currents-blog/2024/pediatric-low-grade-glioma-tovorafenib-braf" onclick=""> <span>Tovorafenib Approved for Some Children with Low-Grade Glioma</span> </a> <div class="description"> <div class="date-author"> <time datetime="2024-05-28T12:00:00Z">May 28, 2024</time>, by Sharon Reynolds </div> <p>FDA has granted an accelerated approval to tovorafenib (Ojemda) for kids and teens who have low-grade glioma with changes in the BRAF gene. In a small clinical trial, the drug shrank or completely eliminated tumors in nearly 70% of patients.</p> <p><a href="/news-events/cancer-currents-blog/2024/pediatric-low-grade-glioma-tovorafenib-braf">Continue Reading ></a></p> </div> </div> </li> </li> <li> <li class="general-list-item general list-item"> <div class="list-item-image image container"> <a class="item-image image" href="/news-events/cancer-currents-blog/2024/childhood-cancer-latin-america-catching-treatment-complications"> <img loading="lazy" src="/sites/g/files/xnrzdm211/files/styles/cgov_thumbnail/public/cgov_image/media_image/2024-02/CC-LMIC-Children-Factoid_0.png?h=44d2104c&itok=dfoo_Tly" width="228" height="171" alt="About 1 in 15 children with cancer in lower-income countries die from treatment-related complications" /> </a> </div> <div class="title-and-desc title desc container"> <a class="title" href="/news-events/cancer-currents-blog/2024/childhood-cancer-latin-america-catching-treatment-complications" onclick=""> <span>How a Simple Tool Is Saving Lives of Children with Cancer in Latin America</span> </a> <div class="description"> <div class="date-author"> <time datetime="2024-02-15T12:00:00Z">February 15, 2024</time>, by Nadia Jaber </div> <p>A system for catching treatment-related complications in children with cancer has proven to be highly effective in many Latin American hospitals. An NCI-funded study aims to help make these early warning systems sustainable.</p> <p><a href="/news-events/cancer-currents-blog/2024/childhood-cancer-latin-america-catching-treatment-complications">Continue Reading ></a></p> </div> </div> </li> </li> <li> <li class="general-list-item general list-item"> <div class="list-item-image image container"> <a class="item-image image" href="/news-events/cancer-currents-blog/2023/blinatumomab-infant-leukemia-survival"> <img loading="lazy" src="/sites/g/files/xnrzdm211/files/styles/cgov_thumbnail/public/cgov_image/media_image/2023-05/blinatumomab-infant-ALL-Cancer-Currents.jpg?h=9fc5c908&itok=194QRIU6" width="228" height="171" alt="Photo of an infant lying on an exam table with an adult holding a stethoscope to the baby's chest." /> </a> </div> <div class="title-and-desc title desc container"> <a class="title" href="/news-events/cancer-currents-blog/2023/blinatumomab-infant-leukemia-survival" onclick=""> <span>Blinatumomab Increases Survival for Infants with an Aggressive Type of ALL</span> </a> <div class="description"> <div class="date-author"> <time datetime="2023-06-08T12:00:00Z">June 8, 2023</time>, by Shana Spindler </div> <p>Giving the drug blinatumomab (Blincyto) after standard chemotherapy substantially increased survival for infants with an aggressive form of acute lymphoblastic leukemia (ALL), a recent study showed. If confirmed in larger studies, the treatment may become standard therapy for infants with ALL caused by KMT2A rearrangements.</p> <p><a href="/news-events/cancer-currents-blog/2023/blinatumomab-infant-leukemia-survival">Continue Reading ></a></p> </div> </div> </li> </li> <li> <li class="general-list-item general list-item"> <div class="list-item-image image container"> <a class="item-image image" href="/news-events/cancer-currents-blog/2023/liquid-biopsy-children-solid-cancers"> <img loading="lazy" src="/sites/g/files/xnrzdm211/files/styles/cgov_thumbnail/public/cgov_image/media_image/2023-04/child%20giving%20blood%20sample.jpg?h=71600fbf&itok=33v8LO-a" width="228" height="171" alt="A young girl with her arm out and gloved hands cleaning a spot on her arm with a swab." /> </a> </div> <div class="title-and-desc title desc container"> <a class="title" href="/news-events/cancer-currents-blog/2023/liquid-biopsy-children-solid-cancers" onclick=""> <span>Liquid Biopsies on the Horizon for Children with Solid Cancers</span> </a> <div class="description"> <div class="date-author"> <time datetime="2023-04-11T12:00:00Z">April 11, 2023</time>, by Elia Ben-Ari </div> <p>Results from a new study highlight the progress being made toward developing liquid biopsies specifically for use in children with solid cancers like Ewing sarcoma and Wilms tumor. The tests can help detect and diagnose cancer and monitor for response to treatment and recurrence.</p> <p><a href="/news-events/cancer-currents-blog/2023/liquid-biopsy-children-solid-cancers">Continue Reading ></a></p> </div> </div> </li> </li> <li> <li class="general-list-item general list-item"> <div class="list-item-image image container"> <a class="item-image image" href="/news-events/cancer-currents-blog/2023/childhood-cancer-dexrazoxane-protects-heart-doxorubicin"> <img loading="lazy" src="/sites/g/files/xnrzdm211/files/styles/cgov_thumbnail/public/cgov_image/media_image/2023-03/ECG%20heart%20failure.jpg?h=88a2628e&itok=LUIA73ad" width="228" height="171" alt="A representative example of a Doppler ECG" /> </a> </div> <div class="title-and-desc title desc container"> <a class="title" href="/news-events/cancer-currents-blog/2023/childhood-cancer-dexrazoxane-protects-heart-doxorubicin" onclick=""> <span>Dexrazoxane Protects the Heart Long Term for Kids Being Treated for Cancer</span> </a> <div class="description"> <div class="date-author"> <time datetime="2023-03-16T12:00:00Z">March 16, 2023</time>, by Shana Spindler </div> <p>Doxorubicin is used to treat many types of childhood cancer, but it can damage the heart. Giving dexrazoxane (Zinecard) before each dose substantially decreases a child鈥檚 risk of treatment-related heart problems in adulthood, new study results show.</p> <p><a href="/news-events/cancer-currents-blog/2023/childhood-cancer-dexrazoxane-protects-heart-doxorubicin">Continue Reading ></a></p> </div> </div> </li> </li> <li> <li class="general-list-item general list-item"> <div class="list-item-image image container"> <a class="item-image image" href="/news-events/cancer-currents-blog/2022/fda-brentuximab-children-hodgkin-lymphoma"> <img loading="lazy" src="/sites/g/files/xnrzdm211/files/styles/cgov_thumbnail/public/cgov_image/media_image/2022-12/DCTD-brentuximab.png?h=8901dc45&itok=qEnopPOK" width="228" height="171" alt="An illustration of brentuximab's mechanism of action." /> </a> </div> <div class="title-and-desc title desc container"> <a class="title" href="/news-events/cancer-currents-blog/2022/fda-brentuximab-children-hodgkin-lymphoma" onclick=""> <span>Brentuximab Approved for High-Risk Hodgkin Lymphoma in Children and Adolescents</span> </a> <div class="description"> <div class="date-author"> <time datetime="2022-12-15T12:00:00Z">December 15, 2022</time>, by Edward Winstead </div> <p>Based on an NCI-sponsored clinical trial conducted by the Children鈥檚 Oncology Group, FDA has approved the drug brentuximab vedotin (Adcetris) in combination with chemotherapy for some children and adolescents with Hodgkin lymphoma.</p> <p><a href="/news-events/cancer-currents-blog/2022/fda-brentuximab-children-hodgkin-lymphoma">Continue Reading ></a></p> </div> </div> </li> </li> <li> <li class="general-list-item general list-item"> <div class="list-item-image image container"> <a class="item-image image" href="/news-events/cancer-currents-blog/2022/rhabdomyosarcoma-trametinib-ganitumab-shrinks-tumors"> <img loading="lazy" src="/sites/g/files/xnrzdm211/files/styles/cgov_thumbnail/public/cgov_image/media_image/2022-12/ganitumab%20trametinib%20combo.PNG?h=4dd3e1e4&itok=SJ1YOQao" width="228" height="171" alt="A diagram of the signaling pathway in cells blocked by ganitumab and trametinib." /> </a> </div> <div class="title-and-desc title desc container"> <a class="title" href="/news-events/cancer-currents-blog/2022/rhabdomyosarcoma-trametinib-ganitumab-shrinks-tumors" onclick=""> <span>Drug Combination Shows Promise for Rhabdomyosarcoma, but Can It Get to Clinical Trials?</span> </a> <div class="description"> <div class="date-author"> <time datetime="2022-12-09T12:00:00Z">December 9, 2022</time>, by Linda Wang </div> <p>An NCI study in mice has identified a drug combination that may help treat children with rhabdomyosarcoma. But one of the drugs, ganitumab, is no longer being made. Based on the study's promising results, the NCI researchers who led the study want to test the combination in humans.</p> <p><a href="/news-events/cancer-currents-blog/2022/rhabdomyosarcoma-trametinib-ganitumab-shrinks-tumors">Continue Reading ></a></p> </div> </div> </li> </li> <li> <li class="general-list-item general list-item"> <div class="list-item-image image container"> <a class="item-image image" href="/news-events/cancer-currents-blog/2022/fda-sodium-thiosulfate-cisplatin-hearing-loss-children"> <img loading="lazy" src="/sites/g/files/xnrzdm211/files/styles/cgov_thumbnail/public/cgov_image/media_image/2022-10/child-hearing-test.jpg?h=df6faf29&itok=KPfQXzTM" width="228" height="171" alt="" /> </a> </div> <div class="title-and-desc title desc container"> <a class="title" href="/news-events/cancer-currents-blog/2022/fda-sodium-thiosulfate-cisplatin-hearing-loss-children" onclick=""> <span>Sodium Thiosulfate Approved to Reduce Chemo-Related Hearing Loss in Children with Cancer</span> </a> <div class="description"> <div class="date-author"> <time datetime="2022-10-06T12:00:00Z">October 6, 2022</time>, by Edward Winstead </div> <p>The chemotherapy cisplatin often causes permanent hearing loss. Sodium thiosulfate (Pedmark) is the first treatment approved by FDA that can reduce the risk of hearing loss and the severity of damage to the inner ear in children treated with cisplatin.</p> <p><a href="/news-events/cancer-currents-blog/2022/fda-sodium-thiosulfate-cisplatin-hearing-loss-children">Continue Reading ></a></p> </div> </div> </li> </li> <li> <li class="general-list-item general list-item"> <div class="list-item-image image container"> <a class="item-image image" href="/news-events/cancer-currents-blog/2022/childhood-cancer-research-advances-cog-hawkins"> <img loading="lazy" src="/sites/g/files/xnrzdm211/files/styles/cgov_thumbnail/public/cgov_image/media_image/2022-09/child%20with%20cancer%20and%20mother.jpg?h=78517eb0&itok=prhziQMJ" width="228" height="171" alt="A child with cancer and his mother talking with family via a tablet computer." /> </a> </div> <div class="title-and-desc title desc container"> <a class="title" href="/news-events/cancer-currents-blog/2022/childhood-cancer-research-advances-cog-hawkins" onclick=""> <span>Making Transformative Advances against Childhood Cancer: A Conversation with Dr. Doug Hawkins</span> </a> <div class="description"> <div class="date-author"> <time datetime="2022-09-28T12:00:00Z">September 28, 2022</time>, by Carmen Phillips </div> <p>Dr. Doug Hawkins, chair of the NCI-funded Children鈥檚 Oncology Group, discusses advances in treating children with cancer, COG鈥檚 role in conducting clinical trials, and efforts like the Childhood Cancer Data Initiative and Molecular Characterization Initiative.</p> <p><a href="/news-events/cancer-currents-blog/2022/childhood-cancer-research-advances-cog-hawkins">Continue Reading ></a></p> </div> </div> </li> </li> <li> <li class="general-list-item general list-item"> <div class="list-item-image image container"> <a class="item-image image" href="/news-events/cancer-currents-blog/2022/study-confirms-dinutiximab-high-risk-neuroblastoma"> <img loading="lazy" src="/sites/g/files/xnrzdm211/files/styles/cgov_thumbnail/public/cgov_image/media_image/2022-08/neuroblastoma%20fluorescence%20microscope.jpg?h=10c8fbfb&itok=df0lgDcr" width="228" height="171" alt="A fluorescence micrograph of neuroblastoma cells, with cell nuclei stained red. " /> </a> </div> <div class="title-and-desc title desc container"> <a class="title" href="/news-events/cancer-currents-blog/2022/study-confirms-dinutiximab-high-risk-neuroblastoma" onclick=""> <span>Study Confirms Dinutuximab Extends Life for Children with High-Risk Neuroblastoma</span> </a> <div class="description"> <div class="date-author"> <time datetime="2022-09-06T12:00:00Z">September 6, 2022</time>, by Linda Wang </div> <p>Researchers have confirmed that the immunotherapy drug dinutuximab (Unituxin) can help children with high-risk neuroblastoma live longer. The finding is based on a trial of nearly 1,200 children with the disease.</p> <p><a href="/news-events/cancer-currents-blog/2022/study-confirms-dinutiximab-high-risk-neuroblastoma">Continue Reading ></a></p> </div> </div> </li> </li> <li> <li class="general-list-item general list-item"> <div class="list-item-image image container"> <a class="item-image image" href="/news-events/cancer-currents-blog/2022/rhabdomyosarcoma-targeting-fusion-protein-kdm4b"> <img loading="lazy" src="/sites/g/files/xnrzdm211/files/styles/cgov_thumbnail/public/cgov_image/media_image/2022-07/Rhabdo%20fusion%20protein%20KDM4B-high%20res.png?h=0f3c8652&itok=r251ozvw" width="228" height="171" alt="An illustration with two panels. On the left, PAX3-FOXO1 interacts with KDM4B in front of stretched-out DNA. On the right, KDM4B is crossed out and the DNA is wound up." /> </a> </div> <div class="title-and-desc title desc container"> <a class="title" href="/news-events/cancer-currents-blog/2022/rhabdomyosarcoma-targeting-fusion-protein-kdm4b" onclick=""> <span>Targeting the Accomplice: A Potential Treatment Approach for Rhabdomyosarcoma </span> </a> <div class="description"> <div class="date-author"> <time datetime="2022-08-03T12:00:00Z">August 3, 2022</time>, by Nadia Jaber </div> <p>The fusion protein that drives the growth and survival of some rhabdomyosarcoma tumors relies on the KDM4B enzyme, researchers have found. Treating mice with a KDM4B-blocking drug and chemotherapy nearly eliminated rhabdomyosarcoma tumors with the fusion protein.</p> <p><a href="/news-events/cancer-currents-blog/2022/rhabdomyosarcoma-targeting-fusion-protein-kdm4b">Continue Reading ></a></p> </div> </div> </li> </li> <li> <li class="general-list-item general list-item"> <div class="list-item-image image container"> <a class="item-image image" href="/news-events/cancer-currents-blog/2022/fda-dabrafenib-trametinib-braf-solid-tumors"> <img loading="lazy" src="/sites/g/files/xnrzdm211/files/styles/cgov_thumbnail/public/cgov_image/media_image/2022-07/Magnetic-Resonance-Imaging.jpg?h=ac20a923&itok=BfGH1Vg9" width="228" height="171" alt="MRI scans of BRAF-positive brain tumors after dabrafenib and trametinib treatment." /> </a> </div> <div class="title-and-desc title desc container"> <a class="title" href="/news-events/cancer-currents-blog/2022/fda-dabrafenib-trametinib-braf-solid-tumors" onclick=""> <span>Dabrafenib鈥揟rametinib Combination Approved for Solid Tumors with BRAF Mutations</span> </a> <div class="description"> <div class="date-author"> <time datetime="2022-07-21T12:00:00Z">July 21, 2022</time>, by Edward Winstead </div> <p>FDA has approved the combination of the targeted drugs dabrafenib (Tafinlar) and trametinib (Mekinist) for nearly any type of advanced solid tumor with a specific mutation in the BRAF gene. Data from the NCI-MATCH trial informed the approval.</p> <p><a href="/news-events/cancer-currents-blog/2022/fda-dabrafenib-trametinib-braf-solid-tumors">Continue Reading ></a></p> </div> </div> </li> </li> <li> <li class="general-list-item general list-item"> <div class="list-item-image image container"> <a class="item-image image" href="/news-events/cancer-currents-blog/2022/glioma-brain-cancer-dabrafenib-trametinib"> <img loading="lazy" src="/sites/g/files/xnrzdm211/files/styles/cgov_thumbnail/public/cgov_image/media_image/2022-06/dabrafenic-trametinib-liquid.jpg?h=1b6673a4&itok=a6nHcFk0" width="228" height="171" alt="" /> </a> </div> <div class="title-and-desc title desc container"> <a class="title" href="/news-events/cancer-currents-blog/2022/glioma-brain-cancer-dabrafenib-trametinib" onclick=""> <span>For Some Kids with Brain Cancer, Targeted Therapy Is Better than Chemo</span> </a> <div class="description"> <div class="date-author"> <time datetime="2022-06-29T12:00:00Z">June 29, 2022</time>, by Nadia Jaber </div> <p>The combination of dabrafenib (Tafinlar) and trametinib (Mekinist) shrank more brain tumors, kept the tumors at bay for longer, and caused fewer side effects than chemotherapy, trial results showed. The children all had glioma with a BRAF V600 mutation that could not be surgically removed or came back after surgery.</p> <p><a href="/news-events/cancer-currents-blog/2022/glioma-brain-cancer-dabrafenib-trametinib">Continue Reading ></a></p> </div> </div> </li> </li> <li> <li class="general-list-item general list-item"> <div class="list-item-image image container"> <a class="item-image image" href="/news-events/cancer-currents-blog/2022/childhood-cancer-survivors-pregnancy-baby-health"> <img loading="lazy" src="/sites/g/files/xnrzdm211/files/styles/cgov_thumbnail/public/cgov_image/media_image/2022-03/Mom%20and%20baby.jpg?h=bcd2ccb0&itok=WJ0oMfH_" width="228" height="171" alt="Mother reclining in hospital bed with newborn infant resting on her chest." /> </a> </div> <div class="title-and-desc title desc container"> <a class="title" href="/news-events/cancer-currents-blog/2022/childhood-cancer-survivors-pregnancy-baby-health" onclick=""> <span>Good News and Cautions about Pregnancy for Childhood Cancer Survivors</span> </a> <div class="description"> <div class="date-author"> <time datetime="2022-03-04T12:00:00Z">March 4, 2022</time>, by Sharon Reynolds </div> <p>As adults, survivors of childhood cancer aren鈥檛 any less likely to have healthy babies than those without a history of cancer, a new study shows. However, they may have more health risks during pregnancy, warranting more intensive obstetric care.</p> <p><a href="/news-events/cancer-currents-blog/2022/childhood-cancer-survivors-pregnancy-baby-health">Continue Reading ></a></p> </div> </div> </li> </li> <li> <li class="general-list-item general list-item"> <div class="list-item-image image container"> <a class="item-image image" href="/news-events/cancer-currents-blog/2021/medulloblastoma-children-test-residual-disease"> <img loading="lazy" src="/sites/g/files/xnrzdm211/files/styles/cgov_thumbnail/public/cgov_image/media_image/2021-12/medulloblastoma-cfDNA-minimal-residual-disease.jpg?h=1fb463c3&itok=1FHzgUk7" width="228" height="171" alt="MRI of a medulloblastoma in the brain." /> </a> </div> <div class="title-and-desc title desc container"> <a class="title" href="/news-events/cancer-currents-blog/2021/medulloblastoma-children-test-residual-disease" onclick=""> <span>Test Detects Early Signs of Remaining Cancer in Kids Treated for Medulloblastoma</span> </a> <div class="description"> <div class="date-author"> <time datetime="2021-12-08T12:00:00Z">December 8, 2021</time>, by Linda Wang </div> <p>A new test could potentially be used to identify children treated for medulloblastoma who are at high risk of their cancer returning. The test detects evidence of remaining cancer in DNA shed from medulloblastoma tumor cells into cerebrospinal fluid.</p> <p><a href="/news-events/cancer-currents-blog/2021/medulloblastoma-children-test-residual-disease">Continue Reading ></a></p> </div> </div> </li> </li> <li> <li class="general-list-item general list-item"> <div class="list-item-image image container"> <a class="item-image image" href="/news-events/cancer-currents-blog/2021/childhood-cancer-accelerating-progress-sharpless"> <img loading="lazy" src="/sites/g/files/xnrzdm211/files/styles/cgov_thumbnail/public/cgov_image/media_image/2021-09/Sharpless%20with%20campers%20cropped%204x3.png?h=07d01bad&itok=kdjtqnQF" width="228" height="171" alt="NCI Director Dr. Norman E. Sharpless with two campers" /> </a> </div> <div class="title-and-desc title desc container"> <a class="title" href="/news-events/cancer-currents-blog/2021/childhood-cancer-accelerating-progress-sharpless" onclick=""> <span>Seeing a Promising Future for Progress against Childhood Cancer</span> </a> <div class="description"> <div class="date-author"> <time datetime="2021-09-16T12:00:00Z">September 16, 2021</time>, by Norman E. Sharpless, M.D. </div> <p>NCI Director Dr. Ned Sharpless discusses progress against childhood cancers, like CAR T-cell therapy and collecting more comprehensive data on children and adolescents with cancer, and the need to better address disparities in childhood cancer.</p> <p><a href="/news-events/cancer-currents-blog/2021/childhood-cancer-accelerating-progress-sharpless">Continue Reading ></a></p> </div> </div> </li> </li> <li> <li class="general-list-item general list-item"> <div class="list-item-image image container"> <a class="item-image image" href="/news-events/cancer-currents-blog/2021/aya-cancer-patient-reported-quality-of-life"> <img loading="lazy" src="/sites/g/files/xnrzdm211/files/styles/cgov_thumbnail/public/cgov_image/media_image/2021-08/AYA%20using%20a%20smartphone.jpg?h=1b6673a4&itok=IMLltF_r" width="228" height="171" alt="AYA using a smartphone" /> </a> </div> <div class="title-and-desc title desc container"> <a class="title" href="/news-events/cancer-currents-blog/2021/aya-cancer-patient-reported-quality-of-life" onclick=""> <span>New Task Force Focuses on Quality of Life for AYAs with Cancer</span> </a> <div class="description"> <div class="date-author"> <time datetime="2021-08-04T12:00:00Z">August 4, 2021</time>, by Elia Ben-Ari </div> <p>Cancer can greatly disrupt life for adolescents and young adults, who are already going through major life changes. Gathering data on how cancer and its treatment affect this age group will improve their quality of life during and beyond treatment.</p> <p><a href="/news-events/cancer-currents-blog/2021/aya-cancer-patient-reported-quality-of-life">Continue Reading ></a></p> </div> </div> </li> </li> <li> <li class="general-list-item general list-item"> <div class="list-item-image image container"> <a class="item-image image" href="/news-events/cancer-currents-blog/2021/fda-rylaze-asparaginase-childhood-leukemia"> <img loading="lazy" src="/sites/g/files/xnrzdm211/files/styles/cgov_thumbnail/public/cgov_image/media_image/2021-07/Female%20doctor%20with%20patient.jpg?h=57e10d92&itok=Wcv5h9xI" width="228" height="171" alt="A female doctor talks with a child laying in a hospital bed." /> </a> </div> <div class="title-and-desc title desc container"> <a class="title" href="/news-events/cancer-currents-blog/2021/fda-rylaze-asparaginase-childhood-leukemia" onclick=""> <span>FDA Approval of Rylaze Will Address Drug Shortage for Childhood ALL</span> </a> <div class="description"> <div class="date-author"> <time datetime="2021-07-29T12:00:00Z">July 29, 2021</time>, by Elia Ben-Ari </div> <p>FDA has approved a new form of asparaginase called Rylaze. The drug was developed to help alleviate shortages of Erwinia asparaginase, a key part of treatment for children and adults with acute lymphoblastic leukemia.</p> <p><a href="/news-events/cancer-currents-blog/2021/fda-rylaze-asparaginase-childhood-leukemia">Continue Reading ></a></p> </div> </div> </li> </li> <li> <li class="general-list-item general list-item"> <div class="list-item-image image container"> <a class="item-image image" href="/news-events/cancer-currents-blog/2021/medulloblastoma-low-dose-volume-radiation"> <img loading="lazy" src="/sites/g/files/xnrzdm211/files/styles/cgov_thumbnail/public/cgov_image/media_image/2021-07/Medulloblastoma%20radiation.jpg?h=17b7f6a2&itok=Q6PpQ1TL" width="228" height="171" alt="CT image of radiation plan for child with medulloblastoma" /> </a> </div> <div class="title-and-desc title desc container"> <a class="title" href="/news-events/cancer-currents-blog/2021/medulloblastoma-low-dose-volume-radiation" onclick=""> <span>For Kids with Medulloblastoma, Trial Suggests Radiation Can Be Tailored</span> </a> <div class="description"> <div class="date-author"> <time datetime="2021-07-16T12:00:00Z">July 16, 2021</time>, by Nadia Jaber </div> <p>Standard radiation for medulloblastoma can cause long-term damage to a child鈥檚 developing brain. A new clinical trial suggests that the volume and dose of radiation could be safely tailored based on genetic features in the patient鈥檚 tumor.</p> <p><a href="/news-events/cancer-currents-blog/2021/medulloblastoma-low-dose-volume-radiation">Continue Reading ></a></p> </div> </div> </li> </li> <li> <li class="general-list-item general list-item"> <div class="list-item-image image container"> <a class="item-image image" href="/news-events/cancer-currents-blog/2021/brentuximab-hodgkin-lymphoma-less-radiation-children-teens"> <img loading="lazy" src="/sites/g/files/xnrzdm211/files/styles/cgov_thumbnail/public/cgov_image/media_image/2021-05/dividing%20cell.jpg?h=3eabf0d3&itok=slMX9ZKr" width="228" height="171" alt="" /> </a> </div> <div class="title-and-desc title desc container"> <a class="title" href="/news-events/cancer-currents-blog/2021/brentuximab-hodgkin-lymphoma-less-radiation-children-teens" onclick=""> <span>Brentuximab May Mean Less Radiation for Children, Teens with Hodgkin Lymphoma</span> </a> <div class="description"> <div class="date-author"> <time datetime="2021-05-07T12:00:00Z">May 7, 2021</time>, by Elia Ben-Ari </div> <p>In a recent study, a treatment regimen using brentuximab vedotin (Adcetris) instead of the chemotherapy drug vincristine allowed some children and teens with advanced Hodgkin lymphoma to avoid radiation therapy鈥攁nd the long-term health problems that can come with it.</p> <p><a href="/news-events/cancer-currents-blog/2021/brentuximab-hodgkin-lymphoma-less-radiation-children-teens">Continue Reading ></a></p> </div> </div> </li> </li> </ul> </div> <div class="blog-pager clearfix"> <a class="older" href="/news-events/cancer-currents-blog?topic=childhood-cancer&page=1">< Older Posts</a> </div> </div> </div> </ul> </div> </div> </div> </div> <footer class="article-footer"> </footer> </article>  </div> </main> </div>   <div class="cgdpl desktop:grid-col-3"> <div id="nvcgSlListBlogRTRail" class="right-rail"> <div class="slot-item"> <div 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href="/news-events/cancer-currents-blog?year=2024&month=08"> August </a> (9) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2024&month=07"> July </a> (6) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2024&month=06"> June </a> (5) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2024&month=05"> May </a> (9) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2024&month=04"> April </a> (6) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2024&month=03"> March </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2024&month=02"> February </a> (6) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2024&month=01"> January </a> (6) </li> </ul> <h3> 2023 </h3> <ul class="ui-helper-reset"> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2023&month=12"> December </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2023&month=11"> November </a> (6) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2023&month=10"> October </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2023&month=09"> September </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2023&month=08"> August </a> (6) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2023&month=07"> July </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2023&month=06"> June </a> (8) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2023&month=05"> May </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2023&month=04"> April </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2023&month=03"> March </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2023&month=02"> February </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2023&month=01"> January </a> (6) </li> </ul> <h3> 2022 </h3> <ul class="ui-helper-reset"> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2022&month=12"> December </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2022&month=11"> November </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2022&month=10"> October </a> (5) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2022&month=09"> September </a> (6) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2022&month=08"> August </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2022&month=07"> July </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2022&month=06"> June </a> (8) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2022&month=05"> May </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2022&month=04"> April </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2022&month=03"> March </a> (8) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2022&month=02"> February </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2022&month=01"> January </a> (6) </li> </ul> <h3> 2021 </h3> <ul class="ui-helper-reset"> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2021&month=12"> December </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2021&month=11"> November </a> (4) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2021&month=10"> October </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2021&month=09"> September </a> (9) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2021&month=08"> August </a> (6) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2021&month=07"> July </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2021&month=06"> June </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2021&month=05"> May </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2021&month=04"> April </a> (8) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2021&month=03"> March </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2021&month=02"> February </a> (5) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2021&month=01"> January </a> (6) </li> </ul> <h3> 2020 </h3> <ul class="ui-helper-reset"> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2020&month=12"> December </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2020&month=11"> November </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2020&month=10"> October </a> (8) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2020&month=09"> September </a> (6) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2020&month=08"> August </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2020&month=07"> July </a> (9) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2020&month=06"> June </a> (8) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2020&month=05"> May </a> (8) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2020&month=04"> April </a> (10) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2020&month=03"> March </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2020&month=02"> February </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2020&month=01"> January </a> (7) </li> </ul> <h3> 2019 </h3> <ul class="ui-helper-reset"> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2019&month=12"> December </a> (6) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2019&month=11"> November </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2019&month=10"> October </a> (8) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2019&month=09"> September </a> (8) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2019&month=08"> August </a> (6) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2019&month=07"> July </a> (8) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2019&month=06"> June </a> (6) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2019&month=05"> May </a> (9) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2019&month=04"> April </a> (7) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2019&month=03"> March </a> (10) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2019&month=02"> February </a> (9) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2019&month=01"> January </a> (6) </li> </ul> <h3> 2018 </h3> <ul class="ui-helper-reset"> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2018&month=12"> December </a> (9) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2018&month=11"> November </a> (9) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2018&month=10"> October </a> (9) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2018&month=09"> September </a> (11) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2018&month=08"> August </a> (9) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2018&month=07"> July </a> (9) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2018&month=06"> June </a> (12) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2018&month=05"> May </a> (9) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2018&month=04"> April </a> (10) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2018&month=03"> March </a> (11) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2018&month=02"> February </a> (11) </li> <li class="month"> <a href="/news-events/cancer-currents-blog?year=2018&month=01"> January </a> (10) </li> </ul> </div> </div> </div> </div> </div> </div>  </div> <section class="cgdp-page-options cgdp-page-options--bottom" aria-label="Page options bottom"> <button 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