CINXE.COM
Clinical Results - Certis Oncology
<!doctype html> <html lang="en"> <head> <meta charset="utf-8" /> <title>Clinical Results - Certis Oncology</title> <meta name="viewport" content="width=device-width, initial-scale=1.0, maximum-scale=1.0, user-scalable=no" /> <link rel="stylesheet" media="all" href="/wp-content/themes/certis/dist/css/style.css?v2"/> <!-- google tag manager --> <script>(function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start': new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0], j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src= 'https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f); })(window,document,'script','dataLayer','GTM-K5GS2LR');</script> <meta name='robots' content='index, follow, max-image-preview:large, max-snippet:-1, max-video-preview:-1' /> <!-- This site is optimized with the Yoast SEO Premium plugin v21.6 (Yoast SEO v23.8) - https://yoast.com/wordpress/plugins/seo/ --> <meta name="description" content="Clinical trials performed at UCLA concluded that pharmacology studies using Certis Orthotopic PDX can rule out ineffective drugs and identify effective drugs for patients." /> <link rel="canonical" href="https://www.certisoncology.com/resources/clinical-results/" /> <meta property="og:locale" content="en_US" /> <meta property="og:type" content="article" /> <meta property="og:title" content="Clinical Results" /> <meta property="og:description" content="Clinical trials performed at UCLA concluded that pharmacology studies using Certis Orthotopic PDX can rule out ineffective drugs and identify effective drugs for patients." /> <meta property="og:url" content="https://www.certisoncology.com/resources/clinical-results/" /> <meta property="og:site_name" content="Certis Oncology" /> <meta property="article:publisher" content="https://www.facebook.com/CertisOncology/" /> <meta property="article:modified_time" content="2024-03-28T23:40:04+00:00" /> <meta name="twitter:card" content="summary_large_image" /> <meta name="twitter:site" content="@CertisOncology" /> <script type="application/ld+json" class="yoast-schema-graph">{"@context":"https://schema.org","@graph":[{"@type":"WebPage","@id":"https://www.certisoncology.com/resources/clinical-results/","url":"https://www.certisoncology.com/resources/clinical-results/","name":"Clinical Results - Certis Oncology","isPartOf":{"@id":"https://www.certisoncology.com/#website"},"datePublished":"2020-09-25T22:03:15+00:00","dateModified":"2024-03-28T23:40:04+00:00","description":"Clinical trials performed at UCLA concluded that pharmacology studies using Certis Orthotopic PDX can rule out ineffective drugs and identify effective drugs for patients.","breadcrumb":{"@id":"https://www.certisoncology.com/resources/clinical-results/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https://www.certisoncology.com/resources/clinical-results/"]}]},{"@type":"BreadcrumbList","@id":"https://www.certisoncology.com/resources/clinical-results/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https://www.certisoncology.com/"},{"@type":"ListItem","position":2,"name":"Resources","item":"https://www.certisoncology.com/resources/"},{"@type":"ListItem","position":3,"name":"Clinical Results"}]},{"@type":"WebSite","@id":"https://www.certisoncology.com/#website","url":"https://www.certisoncology.com/","name":"Certis Oncology","description":"","publisher":{"@id":"https://www.certisoncology.com/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https://www.certisoncology.com/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https://www.certisoncology.com/#organization","name":"Certis Oncology","url":"https://www.certisoncology.com/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https://www.certisoncology.com/#/schema/logo/image/","url":"https://www.certisoncology.com/wp-content/uploads/certis-color.svg","contentUrl":"https://www.certisoncology.com/wp-content/uploads/certis-color.svg","width":1,"height":1,"caption":"Certis Oncology"},"image":{"@id":"https://www.certisoncology.com/#/schema/logo/image/"},"sameAs":["https://www.facebook.com/CertisOncology/","https://x.com/CertisOncology","https://www.linkedin.com/company/certis-oncology","https://www.facebook.com/CertisOncology","https://www.instagram.com/certis_oncology","https://www.youtube.com/channel/UCeX4_jh3RlNKxQxZ89_utjg","https://www.certisoncology.com/for-drug-developers/cancer-model-database-request/"]}]}</script> <!-- / Yoast SEO Premium plugin. --> <style id='classic-theme-styles-inline-css' type='text/css'> /*! This file is auto-generated */ .wp-block-button__link{color:#fff;background-color:#32373c;border-radius:9999px;box-shadow:none;text-decoration:none;padding:calc(.667em + 2px) calc(1.333em + 2px);font-size:1.125em}.wp-block-file__button{background:#32373c;color:#fff;text-decoration:none} </style> <style id='global-styles-inline-css' type='text/css'> :root{--wp--preset--aspect-ratio--square: 1;--wp--preset--aspect-ratio--4-3: 4/3;--wp--preset--aspect-ratio--3-4: 3/4;--wp--preset--aspect-ratio--3-2: 3/2;--wp--preset--aspect-ratio--2-3: 2/3;--wp--preset--aspect-ratio--16-9: 16/9;--wp--preset--aspect-ratio--9-16: 9/16;--wp--preset--color--black: #000000;--wp--preset--color--cyan-bluish-gray: #abb8c3;--wp--preset--color--white: #ffffff;--wp--preset--color--pale-pink: #f78da7;--wp--preset--color--vivid-red: #cf2e2e;--wp--preset--color--luminous-vivid-orange: #ff6900;--wp--preset--color--luminous-vivid-amber: #fcb900;--wp--preset--color--light-green-cyan: #7bdcb5;--wp--preset--color--vivid-green-cyan: #00d084;--wp--preset--color--pale-cyan-blue: #8ed1fc;--wp--preset--color--vivid-cyan-blue: #0693e3;--wp--preset--color--vivid-purple: #9b51e0;--wp--preset--gradient--vivid-cyan-blue-to-vivid-purple: linear-gradient(135deg,rgba(6,147,227,1) 0%,rgb(155,81,224) 100%);--wp--preset--gradient--light-green-cyan-to-vivid-green-cyan: linear-gradient(135deg,rgb(122,220,180) 0%,rgb(0,208,130) 100%);--wp--preset--gradient--luminous-vivid-amber-to-luminous-vivid-orange: linear-gradient(135deg,rgba(252,185,0,1) 0%,rgba(255,105,0,1) 100%);--wp--preset--gradient--luminous-vivid-orange-to-vivid-red: linear-gradient(135deg,rgba(255,105,0,1) 0%,rgb(207,46,46) 100%);--wp--preset--gradient--very-light-gray-to-cyan-bluish-gray: linear-gradient(135deg,rgb(238,238,238) 0%,rgb(169,184,195) 100%);--wp--preset--gradient--cool-to-warm-spectrum: linear-gradient(135deg,rgb(74,234,220) 0%,rgb(151,120,209) 20%,rgb(207,42,186) 40%,rgb(238,44,130) 60%,rgb(251,105,98) 80%,rgb(254,248,76) 100%);--wp--preset--gradient--blush-light-purple: linear-gradient(135deg,rgb(255,206,236) 0%,rgb(152,150,240) 100%);--wp--preset--gradient--blush-bordeaux: linear-gradient(135deg,rgb(254,205,165) 0%,rgb(254,45,45) 50%,rgb(107,0,62) 100%);--wp--preset--gradient--luminous-dusk: linear-gradient(135deg,rgb(255,203,112) 0%,rgb(199,81,192) 50%,rgb(65,88,208) 100%);--wp--preset--gradient--pale-ocean: linear-gradient(135deg,rgb(255,245,203) 0%,rgb(182,227,212) 50%,rgb(51,167,181) 100%);--wp--preset--gradient--electric-grass: linear-gradient(135deg,rgb(202,248,128) 0%,rgb(113,206,126) 100%);--wp--preset--gradient--midnight: linear-gradient(135deg,rgb(2,3,129) 0%,rgb(40,116,252) 100%);--wp--preset--font-size--small: 13px;--wp--preset--font-size--medium: 20px;--wp--preset--font-size--large: 36px;--wp--preset--font-size--x-large: 42px;--wp--preset--spacing--20: 0.44rem;--wp--preset--spacing--30: 0.67rem;--wp--preset--spacing--40: 1rem;--wp--preset--spacing--50: 1.5rem;--wp--preset--spacing--60: 2.25rem;--wp--preset--spacing--70: 3.38rem;--wp--preset--spacing--80: 5.06rem;--wp--preset--shadow--natural: 6px 6px 9px rgba(0, 0, 0, 0.2);--wp--preset--shadow--deep: 12px 12px 50px rgba(0, 0, 0, 0.4);--wp--preset--shadow--sharp: 6px 6px 0px rgba(0, 0, 0, 0.2);--wp--preset--shadow--outlined: 6px 6px 0px -3px rgba(255, 255, 255, 1), 6px 6px rgba(0, 0, 0, 1);--wp--preset--shadow--crisp: 6px 6px 0px rgba(0, 0, 0, 1);}:where(.is-layout-flex){gap: 0.5em;}:where(.is-layout-grid){gap: 0.5em;}body .is-layout-flex{display: flex;}.is-layout-flex{flex-wrap: wrap;align-items: center;}.is-layout-flex > :is(*, div){margin: 0;}body .is-layout-grid{display: grid;}.is-layout-grid > :is(*, div){margin: 0;}:where(.wp-block-columns.is-layout-flex){gap: 2em;}:where(.wp-block-columns.is-layout-grid){gap: 2em;}:where(.wp-block-post-template.is-layout-flex){gap: 1.25em;}:where(.wp-block-post-template.is-layout-grid){gap: 1.25em;}.has-black-color{color: var(--wp--preset--color--black) !important;}.has-cyan-bluish-gray-color{color: var(--wp--preset--color--cyan-bluish-gray) !important;}.has-white-color{color: var(--wp--preset--color--white) !important;}.has-pale-pink-color{color: var(--wp--preset--color--pale-pink) !important;}.has-vivid-red-color{color: var(--wp--preset--color--vivid-red) !important;}.has-luminous-vivid-orange-color{color: var(--wp--preset--color--luminous-vivid-orange) !important;}.has-luminous-vivid-amber-color{color: var(--wp--preset--color--luminous-vivid-amber) !important;}.has-light-green-cyan-color{color: var(--wp--preset--color--light-green-cyan) !important;}.has-vivid-green-cyan-color{color: var(--wp--preset--color--vivid-green-cyan) !important;}.has-pale-cyan-blue-color{color: var(--wp--preset--color--pale-cyan-blue) !important;}.has-vivid-cyan-blue-color{color: var(--wp--preset--color--vivid-cyan-blue) !important;}.has-vivid-purple-color{color: var(--wp--preset--color--vivid-purple) !important;}.has-black-background-color{background-color: var(--wp--preset--color--black) !important;}.has-cyan-bluish-gray-background-color{background-color: var(--wp--preset--color--cyan-bluish-gray) !important;}.has-white-background-color{background-color: var(--wp--preset--color--white) !important;}.has-pale-pink-background-color{background-color: var(--wp--preset--color--pale-pink) !important;}.has-vivid-red-background-color{background-color: var(--wp--preset--color--vivid-red) !important;}.has-luminous-vivid-orange-background-color{background-color: var(--wp--preset--color--luminous-vivid-orange) !important;}.has-luminous-vivid-amber-background-color{background-color: var(--wp--preset--color--luminous-vivid-amber) !important;}.has-light-green-cyan-background-color{background-color: var(--wp--preset--color--light-green-cyan) !important;}.has-vivid-green-cyan-background-color{background-color: var(--wp--preset--color--vivid-green-cyan) !important;}.has-pale-cyan-blue-background-color{background-color: var(--wp--preset--color--pale-cyan-blue) !important;}.has-vivid-cyan-blue-background-color{background-color: var(--wp--preset--color--vivid-cyan-blue) !important;}.has-vivid-purple-background-color{background-color: var(--wp--preset--color--vivid-purple) !important;}.has-black-border-color{border-color: var(--wp--preset--color--black) !important;}.has-cyan-bluish-gray-border-color{border-color: var(--wp--preset--color--cyan-bluish-gray) !important;}.has-white-border-color{border-color: var(--wp--preset--color--white) !important;}.has-pale-pink-border-color{border-color: var(--wp--preset--color--pale-pink) !important;}.has-vivid-red-border-color{border-color: var(--wp--preset--color--vivid-red) !important;}.has-luminous-vivid-orange-border-color{border-color: var(--wp--preset--color--luminous-vivid-orange) !important;}.has-luminous-vivid-amber-border-color{border-color: var(--wp--preset--color--luminous-vivid-amber) !important;}.has-light-green-cyan-border-color{border-color: var(--wp--preset--color--light-green-cyan) !important;}.has-vivid-green-cyan-border-color{border-color: var(--wp--preset--color--vivid-green-cyan) !important;}.has-pale-cyan-blue-border-color{border-color: var(--wp--preset--color--pale-cyan-blue) !important;}.has-vivid-cyan-blue-border-color{border-color: var(--wp--preset--color--vivid-cyan-blue) !important;}.has-vivid-purple-border-color{border-color: var(--wp--preset--color--vivid-purple) !important;}.has-vivid-cyan-blue-to-vivid-purple-gradient-background{background: var(--wp--preset--gradient--vivid-cyan-blue-to-vivid-purple) !important;}.has-light-green-cyan-to-vivid-green-cyan-gradient-background{background: var(--wp--preset--gradient--light-green-cyan-to-vivid-green-cyan) !important;}.has-luminous-vivid-amber-to-luminous-vivid-orange-gradient-background{background: var(--wp--preset--gradient--luminous-vivid-amber-to-luminous-vivid-orange) !important;}.has-luminous-vivid-orange-to-vivid-red-gradient-background{background: var(--wp--preset--gradient--luminous-vivid-orange-to-vivid-red) !important;}.has-very-light-gray-to-cyan-bluish-gray-gradient-background{background: var(--wp--preset--gradient--very-light-gray-to-cyan-bluish-gray) !important;}.has-cool-to-warm-spectrum-gradient-background{background: var(--wp--preset--gradient--cool-to-warm-spectrum) !important;}.has-blush-light-purple-gradient-background{background: var(--wp--preset--gradient--blush-light-purple) !important;}.has-blush-bordeaux-gradient-background{background: var(--wp--preset--gradient--blush-bordeaux) !important;}.has-luminous-dusk-gradient-background{background: var(--wp--preset--gradient--luminous-dusk) !important;}.has-pale-ocean-gradient-background{background: var(--wp--preset--gradient--pale-ocean) !important;}.has-electric-grass-gradient-background{background: var(--wp--preset--gradient--electric-grass) !important;}.has-midnight-gradient-background{background: var(--wp--preset--gradient--midnight) !important;}.has-small-font-size{font-size: var(--wp--preset--font-size--small) !important;}.has-medium-font-size{font-size: var(--wp--preset--font-size--medium) !important;}.has-large-font-size{font-size: var(--wp--preset--font-size--large) !important;}.has-x-large-font-size{font-size: var(--wp--preset--font-size--x-large) !important;} :where(.wp-block-post-template.is-layout-flex){gap: 1.25em;}:where(.wp-block-post-template.is-layout-grid){gap: 1.25em;} :where(.wp-block-columns.is-layout-flex){gap: 2em;}:where(.wp-block-columns.is-layout-grid){gap: 2em;} :root :where(.wp-block-pullquote){font-size: 1.5em;line-height: 1.6;} </style> <link rel="https://api.w.org/" href="https://www.certisoncology.com/wp-json/" /><link rel="alternate" title="JSON" type="application/json" href="https://www.certisoncology.com/wp-json/wp/v2/pages/145" /><link rel="alternate" title="oEmbed (JSON)" type="application/json+oembed" href="https://www.certisoncology.com/wp-json/oembed/1.0/embed?url=https%3A%2F%2Fwww.certisoncology.com%2Fresources%2Fclinical-results%2F" /> <link rel="alternate" title="oEmbed (XML)" type="text/xml+oembed" href="https://www.certisoncology.com/wp-json/oembed/1.0/embed?url=https%3A%2F%2Fwww.certisoncology.com%2Fresources%2Fclinical-results%2F&format=xml" /> </head> <body> <noscript><iframe src="https://www.googletagmanager.com/ns.html?id=GTM-K5GS2LR" height="0" width="0" style="display:none;visibility:hidden"></iframe></noscript> <div class="app" post="145" :browser="browser" :style="style" v-cloak><!-- vue app --> <navigation :items="{"featured":{"image":{"ID":5534,"id":5534,"title":"CTA_KRAS-CertiScreen-824x424","filename":"CTA_KRAS-CertiScreen-824x424-1.jpg","filesize":49609,"url":"https:\/\/www.certisoncology.com\/wp-content\/uploads\/CTA_KRAS-CertiScreen-824x424-1.jpg","link":"https:\/\/www.certisoncology.com\/observational-clinical-research-study-testing-kras-targeting-therapies\/cta_kras-certiscreen-824x424\/","alt":"","author":"6","description":"","caption":"","name":"cta_kras-certiscreen-824x424","status":"inherit","uploaded_to":5651,"date":"2023-08-24 19:54:06","modified":"2023-10-03 19:51:30","menu_order":0,"mime_type":"image\/jpeg","type":"image","subtype":"jpeg","icon":"https:\/\/www.certisoncology.com\/wp-includes\/images\/media\/default.png","width":824,"height":424,"sizes":{"thumbnail":"https:\/\/www.certisoncology.com\/wp-content\/uploads\/CTA_KRAS-CertiScreen-824x424-1-150x150.jpg","thumbnail-width":150,"thumbnail-height":150,"medium":"https:\/\/www.certisoncology.com\/wp-content\/uploads\/CTA_KRAS-CertiScreen-824x424-1-720x370.jpg","medium-width":300,"medium-height":154,"medium_large":"https:\/\/www.certisoncology.com\/wp-content\/uploads\/CTA_KRAS-CertiScreen-824x424-1-768x395.jpg","medium_large-width":768,"medium_large-height":395,"large":"https:\/\/www.certisoncology.com\/wp-content\/uploads\/CTA_KRAS-CertiScreen-824x424-1.jpg","large-width":824,"large-height":424,"1536x1536":"https:\/\/www.certisoncology.com\/wp-content\/uploads\/CTA_KRAS-CertiScreen-824x424-1.jpg","1536x1536-width":824,"1536x1536-height":424,"2048x2048":"https:\/\/www.certisoncology.com\/wp-content\/uploads\/CTA_KRAS-CertiScreen-824x424-1.jpg","2048x2048-width":824,"2048x2048-height":424,"small":"https:\/\/www.certisoncology.com\/wp-content\/uploads\/CTA_KRAS-CertiScreen-824x424-1-540x278.jpg","small-width":540,"small-height":278,"square-sm":"https:\/\/www.certisoncology.com\/wp-content\/uploads\/CTA_KRAS-CertiScreen-824x424-1-540x424.jpg","square-sm-width":540,"square-sm-height":424,"square-md":"https:\/\/www.certisoncology.com\/wp-content\/uploads\/CTA_KRAS-CertiScreen-824x424-1-720x424.jpg","square-md-width":720,"square-md-height":424,"portrait":"https:\/\/www.certisoncology.com\/wp-content\/uploads\/CTA_KRAS-CertiScreen-824x424-1-640x424.jpg","portrait-width":640,"portrait-height":424,"landscape":"https:\/\/www.certisoncology.com\/wp-content\/uploads\/CTA_KRAS-CertiScreen-824x424-1.jpg","landscape-width":824,"landscape-height":424}},"title":"VALIDATE YOUR KRAS-TARGETING STRATEGY ","content":"<p>Combining Predictive AI + Advanced Cancer Models to Help Direct Oncology Drug Development and Clinic Research Studies.<\/p>\n","link":{"title":"Learn More","url":"https:\/\/www.certisoncology.com\/kras-targeted-oncology-drug-development\/","target":""}},"login":"https:\/\/oncointel.certisoncology.com","navigation":[{"ID":6826,"post_author":"2","post_date":"2024-04-09 20:02:43","post_date_gmt":"2024-02-15 16:53:06","post_content":" ","post_title":"","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"6826","to_ping":"","pinged":"","post_modified":"2024-04-09 20:02:43","post_modified_gmt":"2024-04-09 20:02:43","post_content_filtered":"","post_parent":0,"guid":"https:\/\/www.certisoncology.com\/?p=6826","menu_order":1,"post_type":"nav_menu_item","post_mime_type":"","comment_count":"0","filter":"raw","db_id":6826,"menu_item_parent":"0","object_id":"5","object":"page","type":"post_type","type_label":"Page","url":"https:\/\/www.certisoncology.com\/","title":"Home","target":"","attr_title":"","description":"","classes":[""],"xfn":""},{"ID":5867,"post_author":"1","post_date":"2024-04-09 20:02:43","post_date_gmt":"2024-01-13 00:10:52","post_content":"","post_title":"Drug Developers","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"drug-developers","to_ping":"","pinged":"","post_modified":"2024-04-09 20:02:43","post_modified_gmt":"2024-04-09 20:02:43","post_content_filtered":"","post_parent":0,"guid":"https:\/\/www.certisoncology.com\/?p=5867","menu_order":2,"post_type":"nav_menu_item","post_mime_type":"","comment_count":"0","filter":"raw","db_id":5867,"menu_item_parent":"0","object_id":"5867","object":"custom","type":"custom","type_label":"Custom Link","title":"Drug Developers","url":"#","target":"","attr_title":"","description":"","classes":[""],"xfn":"","children":[{"ID":5872,"post_author":"1","post_date":"2024-04-09 20:02:43","post_date_gmt":"2024-01-13 00:10:52","post_content":"","post_title":"CertisAI\u2122\ufe0f","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"certis-ai","to_ping":"","pinged":"","post_modified":"2024-04-09 20:02:43","post_modified_gmt":"2024-04-09 20:02:43","post_content_filtered":"","post_parent":28,"guid":"https:\/\/www.certisoncology.com\/?p=5872","menu_order":3,"post_type":"nav_menu_item","post_mime_type":"","comment_count":"0","filter":"raw","db_id":5872,"menu_item_parent":"5867","object_id":"5060","object":"page","type":"post_type","type_label":"Page","url":"https:\/\/www.certisoncology.com\/for-drug-developers\/predictive-oncology-intelligence\/","title":"CertisAI\u2122\ufe0f","target":"","attr_title":"","description":"","classes":[""],"xfn":""},{"ID":5930,"post_author":"2","post_date":"2024-04-09 20:02:43","post_date_gmt":"2024-01-13 17:36:22","post_content":" ","post_title":"","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"5930","to_ping":"","pinged":"","post_modified":"2024-04-09 20:02:43","post_modified_gmt":"2024-04-09 20:02:43","post_content_filtered":"","post_parent":28,"guid":"https:\/\/www.certisoncology.com\/?p=5930","menu_order":4,"post_type":"nav_menu_item","post_mime_type":"","comment_count":"0","filter":"raw","db_id":5930,"menu_item_parent":"5867","object_id":"221","object":"page","type":"post_type","type_label":"Page","url":"https:\/\/www.certisoncology.com\/for-drug-developers\/cancer-models-preclinical-studies\/","title":"Cancer Models","target":"","attr_title":"","description":"","classes":[""],"xfn":""},{"ID":5873,"post_author":"1","post_date":"2024-04-09 20:02:43","post_date_gmt":"2024-01-13 00:10:52","post_content":"","post_title":"Custom Models","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"custom-models","to_ping":"","pinged":"","post_modified":"2024-04-09 20:02:43","post_modified_gmt":"2024-04-09 20:02:43","post_content_filtered":"","post_parent":28,"guid":"https:\/\/www.certisoncology.com\/?p=5873","menu_order":5,"post_type":"nav_menu_item","post_mime_type":"","comment_count":"0","filter":"raw","db_id":5873,"menu_item_parent":"5867","object_id":"137","object":"page","type":"post_type","type_label":"Page","url":"https:\/\/www.certisoncology.com\/for-drug-developers\/custom-model-development\/","title":"Custom Models","target":"","attr_title":"","description":"","classes":[""],"xfn":""},{"ID":5932,"post_author":"2","post_date":"2024-04-09 20:02:43","post_date_gmt":"2024-01-13 17:36:22","post_content":"","post_title":"In Vitro\/Ex Vivo","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"in-vitro-ex-vivo","to_ping":"","pinged":"","post_modified":"2024-04-09 20:02:43","post_modified_gmt":"2024-04-09 20:02:43","post_content_filtered":"","post_parent":28,"guid":"https:\/\/www.certisoncology.com\/?p=5932","menu_order":6,"post_type":"nav_menu_item","post_mime_type":"","comment_count":"0","filter":"raw","db_id":5932,"menu_item_parent":"5867","object_id":"5912","object":"page","type":"post_type","type_label":"Page","url":"https:\/\/www.certisoncology.com\/for-drug-developers\/in-vitro-ex-vivo-pharmacology\/","title":"In Vitro\/Ex Vivo","target":"","attr_title":"","description":"","classes":[""],"xfn":""},{"ID":5933,"post_author":"2","post_date":"2024-04-09 20:02:43","post_date_gmt":"2024-01-13 17:36:22","post_content":"","post_title":"In Vivo","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"in-vivo","to_ping":"","pinged":"","post_modified":"2024-04-09 20:02:43","post_modified_gmt":"2024-04-09 20:02:43","post_content_filtered":"","post_parent":28,"guid":"https:\/\/www.certisoncology.com\/?p=5933","menu_order":7,"post_type":"nav_menu_item","post_mime_type":"","comment_count":"0","filter":"raw","db_id":5933,"menu_item_parent":"5867","object_id":"5914","object":"page","type":"post_type","type_label":"Page","url":"https:\/\/www.certisoncology.com\/for-drug-developers\/in-vivo-pharmacology\/","title":"In Vivo","target":"","attr_title":"","description":"","classes":[""],"xfn":""},{"ID":5934,"post_author":"2","post_date":"2024-04-09 20:02:43","post_date_gmt":"2024-01-13 17:36:22","post_content":"","post_title":"Imaging\/Endpoints","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"imaging-endpoint","to_ping":"","pinged":"","post_modified":"2024-04-09 20:02:43","post_modified_gmt":"2024-04-09 20:02:43","post_content_filtered":"","post_parent":28,"guid":"https:\/\/www.certisoncology.com\/?p=5934","menu_order":8,"post_type":"nav_menu_item","post_mime_type":"","comment_count":"0","filter":"raw","db_id":5934,"menu_item_parent":"5867","object_id":"5916","object":"page","type":"post_type","type_label":"Page","url":"https:\/\/www.certisoncology.com\/for-drug-developers\/imaging-endpoint-analysis\/","title":"Imaging\/Endpoints","target":"","attr_title":"","description":"","classes":[""],"xfn":""},{"ID":5935,"post_author":"2","post_date":"2024-04-09 20:02:44","post_date_gmt":"2024-01-13 17:36:22","post_content":" ","post_title":"","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"5935","to_ping":"","pinged":"","post_modified":"2024-04-09 20:02:44","post_modified_gmt":"2024-04-09 20:02:44","post_content_filtered":"","post_parent":28,"guid":"https:\/\/www.certisoncology.com\/?p=5935","menu_order":9,"post_type":"nav_menu_item","post_mime_type":"","comment_count":"0","filter":"raw","db_id":5935,"menu_item_parent":"5867","object_id":"5918","object":"page","type":"post_type","type_label":"Page","url":"https:\/\/www.certisoncology.com\/for-drug-developers\/immuno-oncology\/","title":"Immuno-Oncology","target":"","attr_title":"","description":"","classes":[""],"xfn":""}]},{"ID":5868,"post_author":"1","post_date":"2024-04-09 20:02:44","post_date_gmt":"2024-01-13 00:10:52","post_content":"","post_title":"Oncologists","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"oncologists","to_ping":"","pinged":"","post_modified":"2024-04-09 20:02:44","post_modified_gmt":"2024-04-09 20:02:44","post_content_filtered":"","post_parent":0,"guid":"https:\/\/www.certisoncology.com\/?p=5868","menu_order":10,"post_type":"nav_menu_item","post_mime_type":"","comment_count":"0","filter":"raw","db_id":5868,"menu_item_parent":"0","object_id":"5868","object":"custom","type":"custom","type_label":"Custom Link","title":"Oncologists","url":"#","target":"","attr_title":"","description":"","classes":[""],"xfn":"","children":[{"ID":5937,"post_author":"2","post_date":"2024-04-09 20:02:44","post_date_gmt":"2024-01-13 17:42:17","post_content":"","post_title":"Order YourPDX<sup>\u00ae<\/sup>","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"5937","to_ping":"","pinged":"","post_modified":"2024-04-09 20:02:44","post_modified_gmt":"2024-04-09 20:02:44","post_content_filtered":"","post_parent":389,"guid":"https:\/\/www.certisoncology.com\/?p=5937","menu_order":11,"post_type":"nav_menu_item","post_mime_type":"","comment_count":"0","filter":"raw","db_id":5937,"menu_item_parent":"5868","object_id":"26","object":"page","type":"post_type","type_label":"Page","url":"https:\/\/www.certisoncology.com\/for-oncologists\/order-yourpdx\/","title":"Order YourPDX<sup>\u00ae<\/sup>","target":"","attr_title":"","description":"","classes":[""],"xfn":""},{"ID":5938,"post_author":"2","post_date":"2024-04-09 20:02:44","post_date_gmt":"2024-01-13 17:42:17","post_content":" ","post_title":"","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"5938","to_ping":"","pinged":"","post_modified":"2024-04-09 20:02:44","post_modified_gmt":"2024-04-09 20:02:44","post_content_filtered":"","post_parent":389,"guid":"https:\/\/www.certisoncology.com\/?p=5938","menu_order":12,"post_type":"nav_menu_item","post_mime_type":"","comment_count":"0","filter":"raw","db_id":5938,"menu_item_parent":"5868","object_id":"5923","object":"page","type":"post_type","type_label":"Page","url":"https:\/\/www.certisoncology.com\/for-oncologists\/clinical-research\/","title":"Clinical Research","target":"","attr_title":"","description":"","classes":[""],"xfn":""},{"ID":5876,"post_author":"1","post_date":"2024-04-09 20:02:44","post_date_gmt":"2024-01-13 00:10:52","post_content":" ","post_title":"","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"5876","to_ping":"","pinged":"","post_modified":"2024-04-09 20:02:44","post_modified_gmt":"2024-04-09 20:02:44","post_content_filtered":"","post_parent":389,"guid":"https:\/\/www.certisoncology.com\/?p=5876","menu_order":13,"post_type":"nav_menu_item","post_mime_type":"","comment_count":"0","filter":"raw","db_id":5876,"menu_item_parent":"5868","object_id":"215","object":"page","type":"post_type","type_label":"Page","url":"https:\/\/www.certisoncology.com\/for-oncologists\/patient-education\/","title":"Patient Education","target":"","attr_title":"","description":"","classes":[""],"xfn":""}]},{"ID":5869,"post_author":"1","post_date":"2024-04-09 20:02:44","post_date_gmt":"2024-01-13 00:10:52","post_content":"","post_title":"About","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"about","to_ping":"","pinged":"","post_modified":"2024-04-09 20:02:44","post_modified_gmt":"2024-04-09 20:02:44","post_content_filtered":"","post_parent":0,"guid":"https:\/\/www.certisoncology.com\/?p=5869","menu_order":14,"post_type":"nav_menu_item","post_mime_type":"","comment_count":"0","filter":"raw","db_id":5869,"menu_item_parent":"0","object_id":"5869","object":"custom","type":"custom","type_label":"Custom Link","title":"About","url":"#","target":"","attr_title":"","description":"","classes":[""],"xfn":"","children":[{"ID":5882,"post_author":"1","post_date":"2024-04-09 20:02:44","post_date_gmt":"2024-01-13 00:10:52","post_content":" ","post_title":"","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"5882","to_ping":"","pinged":"","post_modified":"2024-04-09 20:02:44","post_modified_gmt":"2024-04-09 20:02:44","post_content_filtered":"","post_parent":120,"guid":"https:\/\/www.certisoncology.com\/?p=5882","menu_order":15,"post_type":"nav_menu_item","post_mime_type":"","comment_count":"0","filter":"raw","db_id":5882,"menu_item_parent":"5869","object_id":"124","object":"page","type":"post_type","type_label":"Page","url":"https:\/\/www.certisoncology.com\/about-us\/mission-vision-values\/","title":"Mission, Vision & Values","target":"","attr_title":"","description":"","classes":[""],"xfn":""},{"ID":5883,"post_author":"1","post_date":"2024-04-09 20:02:44","post_date_gmt":"2024-01-13 00:10:52","post_content":" ","post_title":"","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"team","to_ping":"","pinged":"","post_modified":"2024-04-09 20:02:44","post_modified_gmt":"2024-04-09 20:02:44","post_content_filtered":"","post_parent":120,"guid":"https:\/\/www.certisoncology.com\/?p=5883","menu_order":16,"post_type":"nav_menu_item","post_mime_type":"","comment_count":"0","filter":"raw","db_id":5883,"menu_item_parent":"5869","object_id":"126","object":"page","type":"post_type","type_label":"Page","url":"https:\/\/www.certisoncology.com\/about-us\/our-team\/","title":"Team","target":"","attr_title":"","description":"","classes":[""],"xfn":""},{"ID":5884,"post_author":"1","post_date":"2024-04-09 20:02:44","post_date_gmt":"2024-01-13 00:10:52","post_content":" ","post_title":"","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"5884","to_ping":"","pinged":"","post_modified":"2024-04-09 20:02:44","post_modified_gmt":"2024-04-09 20:02:44","post_content_filtered":"","post_parent":120,"guid":"https:\/\/www.certisoncology.com\/?p=5884","menu_order":17,"post_type":"nav_menu_item","post_mime_type":"","comment_count":"0","filter":"raw","db_id":5884,"menu_item_parent":"5869","object_id":"4361","object":"page","type":"post_type","type_label":"Page","url":"https:\/\/www.certisoncology.com\/about-us\/our-story\/","title":"Our Story","target":"","attr_title":"","description":"","classes":[""],"xfn":""},{"ID":5885,"post_author":"1","post_date":"2024-04-09 20:02:44","post_date_gmt":"2024-01-13 00:10:52","post_content":" ","post_title":"","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"5885","to_ping":"","pinged":"","post_modified":"2024-04-09 20:02:44","post_modified_gmt":"2024-04-09 20:02:44","post_content_filtered":"","post_parent":120,"guid":"https:\/\/www.certisoncology.com\/?p=5885","menu_order":18,"post_type":"nav_menu_item","post_mime_type":"","comment_count":"0","filter":"raw","db_id":5885,"menu_item_parent":"5869","object_id":"19","object":"page","type":"post_type","type_label":"Page","url":"https:\/\/www.certisoncology.com\/about-us\/careers\/","title":"Careers","target":"","attr_title":"","description":"","classes":[""],"xfn":""},{"ID":7286,"post_author":"6","post_date":"2024-04-09 20:02:44","post_date_gmt":"2024-03-25 15:53:53","post_content":" ","post_title":"","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"7286","to_ping":"","pinged":"","post_modified":"2024-04-09 20:02:44","post_modified_gmt":"2024-04-09 20:02:44","post_content_filtered":"","post_parent":120,"guid":"https:\/\/www.certisoncology.com\/7286\/","menu_order":19,"post_type":"nav_menu_item","post_mime_type":"","comment_count":"0","filter":"raw","db_id":7286,"menu_item_parent":"5869","object_id":"149","object":"page","type":"post_type","type_label":"Page","url":"https:\/\/www.certisoncology.com\/about-us\/news\/","title":"Company News","target":"","attr_title":"","description":"","classes":[""],"xfn":""},{"ID":5939,"post_author":"2","post_date":"2024-04-09 20:02:44","post_date_gmt":"2024-01-13 17:42:17","post_content":" ","post_title":"","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"5939","to_ping":"","pinged":"","post_modified":"2024-04-09 20:02:44","post_modified_gmt":"2024-04-09 20:02:44","post_content_filtered":"","post_parent":0,"guid":"https:\/\/www.certisoncology.com\/?p=5939","menu_order":20,"post_type":"nav_menu_item","post_mime_type":"","comment_count":"0","filter":"raw","db_id":5939,"menu_item_parent":"5869","object_id":"364","object":"page","type":"post_type","type_label":"Page","url":"https:\/\/www.certisoncology.com\/contact-us\/","title":"Contact Us","target":"","attr_title":"","description":"","classes":[""],"xfn":""}]},{"ID":5870,"post_author":"1","post_date":"2024-04-09 20:02:44","post_date_gmt":"2024-01-13 00:10:52","post_content":"","post_title":"Resource Library","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"resource-library","to_ping":"","pinged":"","post_modified":"2024-04-09 20:02:44","post_modified_gmt":"2024-04-09 20:02:44","post_content_filtered":"","post_parent":0,"guid":"https:\/\/www.certisoncology.com\/?p=5870","menu_order":21,"post_type":"nav_menu_item","post_mime_type":"","comment_count":"0","filter":"raw","db_id":5870,"menu_item_parent":"0","object_id":"5870","object":"custom","type":"custom","type_label":"Custom Link","title":"Resource Library","url":"#","target":"","attr_title":"","description":"","classes":[""],"xfn":"","children":[{"ID":5878,"post_author":"1","post_date":"2024-04-09 20:02:44","post_date_gmt":"2024-01-13 00:10:52","post_content":" ","post_title":"","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"5878","to_ping":"","pinged":"","post_modified":"2024-04-09 20:02:44","post_modified_gmt":"2024-04-09 20:02:44","post_content_filtered":"","post_parent":141,"guid":"https:\/\/www.certisoncology.com\/?p=5878","menu_order":22,"post_type":"nav_menu_item","post_mime_type":"","comment_count":"0","filter":"raw","db_id":5878,"menu_item_parent":"5870","object_id":"143","object":"page","type":"post_type","type_label":"Page","url":"https:\/\/www.certisoncology.com\/resources\/cancer-market-facts\/","title":"Cancer Facts","target":"","attr_title":"","description":"","classes":[""],"xfn":""},{"ID":5879,"post_author":"1","post_date":"2024-04-09 20:02:44","post_date_gmt":"2024-01-13 00:10:52","post_content":" ","post_title":"","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"5879","to_ping":"","pinged":"","post_modified":"2024-04-09 20:02:44","post_modified_gmt":"2024-04-09 20:02:44","post_content_filtered":"","post_parent":141,"guid":"https:\/\/www.certisoncology.com\/?p=5879","menu_order":23,"post_type":"nav_menu_item","post_mime_type":"","comment_count":"0","filter":"raw","db_id":5879,"menu_item_parent":"5870","object_id":"145","object":"page","type":"post_type","type_label":"Page","url":"https:\/\/www.certisoncology.com\/resources\/clinical-results\/","title":"Clinical Results","target":"","attr_title":"","description":"","classes":[""],"xfn":""},{"ID":5880,"post_author":"1","post_date":"2024-04-09 20:02:44","post_date_gmt":"2024-01-13 00:10:52","post_content":" ","post_title":"","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"5880","to_ping":"","pinged":"","post_modified":"2024-04-09 20:02:44","post_modified_gmt":"2024-04-09 20:02:44","post_content_filtered":"","post_parent":141,"guid":"https:\/\/www.certisoncology.com\/?p=5880","menu_order":24,"post_type":"nav_menu_item","post_mime_type":"","comment_count":"0","filter":"raw","db_id":5880,"menu_item_parent":"5870","object_id":"147","object":"page","type":"post_type","type_label":"Page","url":"https:\/\/www.certisoncology.com\/resources\/supporting-research\/","title":"Supporting Research","target":"","attr_title":"","description":"","classes":[""],"xfn":""},{"ID":7243,"post_author":"1","post_date":"2024-04-09 20:02:44","post_date_gmt":"2024-02-29 01:36:09","post_content":" ","post_title":"","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"7243","to_ping":"","pinged":"","post_modified":"2024-04-09 20:02:44","post_modified_gmt":"2024-04-09 20:02:44","post_content_filtered":"","post_parent":141,"guid":"https:\/\/www.certisoncology.com\/?p=7243","menu_order":25,"post_type":"nav_menu_item","post_mime_type":"","comment_count":"0","filter":"raw","db_id":7243,"menu_item_parent":"5870","object_id":"7237","object":"page","type":"post_type","type_label":"Page","url":"https:\/\/www.certisoncology.com\/resources\/media\/","title":"Media","target":"","attr_title":"","description":"","classes":[""],"xfn":""},{"ID":7296,"post_author":"6","post_date":"2024-04-09 20:02:44","post_date_gmt":"2024-03-25 20:25:22","post_content":"","post_title":"White Papers","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"white-papers","to_ping":"","pinged":"","post_modified":"2024-04-09 20:02:44","post_modified_gmt":"2024-04-09 20:02:44","post_content_filtered":"","post_parent":0,"guid":"https:\/\/www.certisoncology.com\/?p=7296","menu_order":26,"post_type":"nav_menu_item","post_mime_type":"","comment_count":"0","filter":"raw","db_id":7296,"menu_item_parent":"5870","object_id":"7296","object":"custom","type":"custom","type_label":"Custom Link","title":"White Papers","url":"https:\/\/whitepapers.certisoncology.com\/","target":"","attr_title":"","description":"","classes":[""],"xfn":""}]},{"ID":5871,"post_author":"1","post_date":"2024-04-09 20:02:44","post_date_gmt":"2024-01-13 00:10:52","post_content":"","post_title":"Contact","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"contact","to_ping":"","pinged":"","post_modified":"2024-04-09 20:02:44","post_modified_gmt":"2024-04-09 20:02:44","post_content_filtered":"","post_parent":0,"guid":"https:\/\/www.certisoncology.com\/?p=5871","menu_order":27,"post_type":"nav_menu_item","post_mime_type":"","comment_count":"0","filter":"raw","db_id":5871,"menu_item_parent":"0","object_id":"364","object":"page","type":"post_type","type_label":"Page","url":"https:\/\/www.certisoncology.com\/contact-us\/","title":"Contact","target":"","attr_title":"","description":"","classes":[""],"xfn":""}]}"></navigation> <div class="page"> <component-5f6e4af53220e :arr="{"default":false,"group":{"image":{"ID":1655,"id":1655,"title":"hero-banner_about","filename":"hero-banner_about.jpg","filesize":40868,"url":"https:\/\/www.certisoncology.com\/wp-content\/uploads\/hero-banner_about.jpg","link":"https:\/\/www.certisoncology.com\/about-us\/who-we-are\/hero-banner_about\/","alt":"","author":"2","description":"","caption":"","name":"hero-banner_about","status":"inherit","uploaded_to":122,"date":"2020-11-18 15:53:29","modified":"2020-11-18 15:56:15","menu_order":0,"mime_type":"image\/jpeg","type":"image","subtype":"jpeg","icon":"https:\/\/www.certisoncology.com\/wp-includes\/images\/media\/default.png","width":1280,"height":320,"sizes":{"thumbnail":"https:\/\/www.certisoncology.com\/wp-content\/uploads\/hero-banner_about-150x150.jpg","thumbnail-width":150,"thumbnail-height":150,"medium":"https:\/\/www.certisoncology.com\/wp-content\/uploads\/hero-banner_about-720x180.jpg","medium-width":300,"medium-height":75,"medium_large":"https:\/\/www.certisoncology.com\/wp-content\/uploads\/hero-banner_about-768x192.jpg","medium_large-width":768,"medium_large-height":192,"large":"https:\/\/www.certisoncology.com\/wp-content\/uploads\/hero-banner_about-960x240.jpg","large-width":960,"large-height":240,"1536x1536":"https:\/\/www.certisoncology.com\/wp-content\/uploads\/hero-banner_about.jpg","1536x1536-width":1280,"1536x1536-height":320,"2048x2048":"https:\/\/www.certisoncology.com\/wp-content\/uploads\/hero-banner_about.jpg","2048x2048-width":1280,"2048x2048-height":320,"small":"https:\/\/www.certisoncology.com\/wp-content\/uploads\/hero-banner_about-540x135.jpg","small-width":540,"small-height":135,"square-sm":"https:\/\/www.certisoncology.com\/wp-content\/uploads\/hero-banner_about-540x320.jpg","square-sm-width":540,"square-sm-height":320,"square-md":"https:\/\/www.certisoncology.com\/wp-content\/uploads\/hero-banner_about-720x320.jpg","square-md-width":720,"square-md-height":320,"portrait":"https:\/\/www.certisoncology.com\/wp-content\/uploads\/hero-banner_about-640x320.jpg","portrait-width":640,"portrait-height":320,"landscape":"https:\/\/www.certisoncology.com\/wp-content\/uploads\/hero-banner_about-960x320.jpg","landscape-width":960,"landscape-height":320}},"text-overlay":{"ID":400,"id":400,"title":"hero-headline_certainty-saves-lives","filename":"hero-headline_certainty-saves-lives.svg","filesize":4262,"url":"https:\/\/www.certisoncology.com\/wp-content\/uploads\/hero-headline_certainty-saves-lives.svg","link":"https:\/\/www.certisoncology.com\/certis-oncology-home\/hero-headline_certainty-saves-lives\/","alt":"Hero Tagline","author":"1","description":"","caption":"","name":"hero-headline_certainty-saves-lives","status":"inherit","uploaded_to":5,"date":"2020-10-02 16:31:37","modified":"2020-10-09 18:05:15","menu_order":0,"mime_type":"image\/svg+xml","type":"image","subtype":"svg+xml","icon":"https:\/\/www.certisoncology.com\/wp-includes\/images\/media\/default.png","width":0,"height":0,"sizes":{"thumbnail":"https:\/\/www.certisoncology.com\/wp-content\/uploads\/hero-headline_certainty-saves-lives.svg","thumbnail-width":1,"thumbnail-height":1,"medium":"https:\/\/www.certisoncology.com\/wp-content\/uploads\/hero-headline_certainty-saves-lives.svg","medium-width":1,"medium-height":1,"medium_large":"https:\/\/www.certisoncology.com\/wp-content\/uploads\/hero-headline_certainty-saves-lives.svg","medium_large-width":1,"medium_large-height":1,"large":"https:\/\/www.certisoncology.com\/wp-content\/uploads\/hero-headline_certainty-saves-lives.svg","large-width":1,"large-height":1,"1536x1536":"https:\/\/www.certisoncology.com\/wp-content\/uploads\/hero-headline_certainty-saves-lives.svg","1536x1536-width":1,"1536x1536-height":1,"2048x2048":"https:\/\/www.certisoncology.com\/wp-content\/uploads\/hero-headline_certainty-saves-lives.svg","2048x2048-width":1,"2048x2048-height":1,"small":"https:\/\/www.certisoncology.com\/wp-content\/uploads\/hero-headline_certainty-saves-lives.svg","small-width":1,"small-height":1,"square-sm":"https:\/\/www.certisoncology.com\/wp-content\/uploads\/hero-headline_certainty-saves-lives.svg","square-sm-width":1,"square-sm-height":1,"square-md":"https:\/\/www.certisoncology.com\/wp-content\/uploads\/hero-headline_certainty-saves-lives.svg","square-md-width":1,"square-md-height":1,"portrait":"https:\/\/www.certisoncology.com\/wp-content\/uploads\/hero-headline_certainty-saves-lives.svg","portrait-width":1,"portrait-height":1,"landscape":"https:\/\/www.certisoncology.com\/wp-content\/uploads\/hero-headline_certainty-saves-lives.svg","landscape-width":1,"landscape-height":1}}}}"></component-5f6e4af53220e><component-5f7ce5112adb2 :singular="""" :arr="[{"ID":1787,"post_author":"1","post_date":"2024-04-09 20:01:55","post_date_gmt":"2020-11-19 19:55:55","post_content":" ","post_title":"","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"1787","to_ping":"","pinged":"","post_modified":"2024-04-09 20:01:55","post_modified_gmt":"2024-04-09 20:01:55","post_content_filtered":"","post_parent":141,"guid":"http:\/\/certisoncology.com\/?p=1787","menu_order":1,"post_type":"nav_menu_item","post_mime_type":"","comment_count":"0","filter":"raw","db_id":1787,"menu_item_parent":"0","object_id":"143","object":"page","type":"post_type","type_label":"Page","url":"https:\/\/www.certisoncology.com\/resources\/cancer-market-facts\/","title":"Cancer Facts","target":"","attr_title":"","description":"","classes":[""],"xfn":""},{"ID":586,"post_author":"1","post_date":"2024-04-09 20:01:55","post_date_gmt":"2020-10-08 22:07:15","post_content":" ","post_title":"","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"586","to_ping":"","pinged":"","post_modified":"2024-04-09 20:01:55","post_modified_gmt":"2024-04-09 20:01:55","post_content_filtered":"","post_parent":141,"guid":"http:\/\/certisoncology.com\/?p=586","menu_order":2,"post_type":"nav_menu_item","post_mime_type":"","comment_count":"0","filter":"raw","db_id":586,"menu_item_parent":"0","object_id":"145","object":"page","type":"post_type","type_label":"Page","url":"https:\/\/www.certisoncology.com\/resources\/clinical-results\/","title":"Clinical Results","target":"","attr_title":"","description":"","classes":[""],"xfn":""},{"ID":2710,"post_author":"1","post_date":"2024-04-09 20:01:55","post_date_gmt":"2021-05-24 20:22:05","post_content":" ","post_title":"","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"2710","to_ping":"","pinged":"","post_modified":"2024-04-09 20:01:55","post_modified_gmt":"2024-04-09 20:01:55","post_content_filtered":"","post_parent":141,"guid":"https:\/\/www.certisoncology.com\/?p=2710","menu_order":3,"post_type":"nav_menu_item","post_mime_type":"","comment_count":"0","filter":"raw","db_id":2710,"menu_item_parent":"0","object_id":"147","object":"page","type":"post_type","type_label":"Page","url":"https:\/\/www.certisoncology.com\/resources\/supporting-research\/","title":"Supporting Research","target":"","attr_title":"","description":"","classes":[""],"xfn":""},{"ID":7244,"post_author":"1","post_date":"2024-04-09 20:01:55","post_date_gmt":"2024-02-29 01:37:03","post_content":" ","post_title":"","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"7244","to_ping":"","pinged":"","post_modified":"2024-04-09 20:01:55","post_modified_gmt":"2024-04-09 20:01:55","post_content_filtered":"","post_parent":141,"guid":"https:\/\/www.certisoncology.com\/?p=7244","menu_order":4,"post_type":"nav_menu_item","post_mime_type":"","comment_count":"0","filter":"raw","db_id":7244,"menu_item_parent":"0","object_id":"7237","object":"page","type":"post_type","type_label":"Page","url":"https:\/\/www.certisoncology.com\/resources\/media\/","title":"Media","target":"","attr_title":"","description":"","classes":[""],"xfn":""},{"ID":7297,"post_author":"6","post_date":"2024-04-09 20:01:55","post_date_gmt":"2024-03-25 20:25:59","post_content":"","post_title":"White Papers","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"white-papers-2","to_ping":"","pinged":"","post_modified":"2024-04-09 20:01:55","post_modified_gmt":"2024-04-09 20:01:55","post_content_filtered":"","post_parent":0,"guid":"https:\/\/www.certisoncology.com\/?p=7297","menu_order":5,"post_type":"nav_menu_item","post_mime_type":"","comment_count":"0","filter":"raw","db_id":7297,"menu_item_parent":"0","object_id":"7297","object":"custom","type":"custom","type_label":"Custom Link","title":"White Papers","url":"https:\/\/whitepapers.certisoncology.com\/","target":"","attr_title":"","description":"","classes":[""],"xfn":""}]"></component-5f7ce5112adb2> <component-5f8f34d69d36a :arr="{"items":[{"ID":1599,"post_author":"6","post_date":"2020-11-16 19:04:21","post_date_gmt":"2020-11-16 19:04:21","post_content":"<!-- wp:paragraph -->\n<p>The parents of a 14-year-old female patient engaged Certis to perform O-PDX pharmacology testing to inform her treatment plan. She had been recently diagnosed with Rhabdomyosarcoma (RMS), a rare type of cancer that forms in skeletal muscle tissue and sometimes hollow organs such as the bladder or uterus. RMS can occur at any age, but it most often affects children. The patient\u2019s family, together with her oncologist, elected to test ten combination therapies using an O-PDX model of the patient\u2019s tumor.<\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:heading -->\n<h2 class=\"wp-block-heading\" id=\"h-methods-results\">Methods & Results<\/h2>\n<!-- \/wp:heading -->\n\n<!-- wp:paragraph -->\n<p>Primary tumor fragments were orthotopically implanted into the right biceps femoris of specialized immunodeficient mice, which were randomized into five animals per therapy and treated for a period of four weeks. The study indicated that six of the ten selected therapies induced tumor regression. The most efficacious treatment, a combination of Mocetinostat and Vinorelbine, reduced tumor volume by 96.5%. By contrast, study cohorts in the control group (which received no treatment), tumor volume increased nearly 700%. The table below compares tumor size over time given all ten therapies and the control.<\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:image {\"id\":1757,\"sizeSlug\":\"medium\",\"className\":\"img-responsive\"} -->\n<figure class=\"wp-block-image size-medium img-responsive\"><img src=\"https:\/\/www.certisoncology.com\/wp-content\/uploads\/XM008-Standard-web-720x482.png\" alt=\"\" class=\"wp-image-1757\"\/><\/figure>\n<!-- \/wp:image -->","post_title":"Extensive, 10-Arm O-PDX Study Predicts Clear \"Therapeutic Winners\" for Pediatric Patient","post_excerpt":"<p>The parents of a 14-year-old female patient engaged Certis to perform O-PDX testing to inform her treatment plan. The extensive, ten-arm O-PDX pharmacology study yielded a clear therapeutic \u201cwinner\u201d.<\/p>\n","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"orthotopic-pdx-pharmacology-study","to_ping":"","pinged":"","post_modified":"2023-05-15 23:24:28","post_modified_gmt":"2023-05-15 23:24:28","post_content_filtered":"","post_parent":0,"guid":"http:\/\/certisoncology.com\/?post_type=type-cl-results&p=1599","menu_order":0,"post_type":"type-cl-results","post_mime_type":"","comment_count":"0","filter":"raw","permalink":"https:\/\/www.certisoncology.com\/clinical-results\/orthotopic-pdx-pharmacology-study\/"},{"ID":1600,"post_author":"6","post_date":"2020-11-16 19:04:10","post_date_gmt":"2020-11-16 19:04:10","post_content":"<!-- wp:paragraph -->\n<p>Rachel, a previously healthy, 46-year-old woman, visited her family doctor in October of 2014, concerned about pain in her right chest wall. Her doctor ordered a CT scan, which revealed a 5.6 cm soft tissue mass with bony destruction in her eleventh rib; she was referred to an oncologist. A biopsy found that Rachel had a rare tumor in the Ewing Sarcoma family.<\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:paragraph -->\n<p><strong>Genetic Profiling Yields No Leads<\/strong><\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:paragraph -->\n<p>Genetic sequencing performed by a third party identified a FUS-ERG gene translocation and CDKN2A mutation in Rachel\u2019s tumor\u2014a condition so rare that bioinformatics algorithms often used to suggest potentially efficacious drugs returned no results.<\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:image {\"align\":\"center\",\"id\":2035,\"sizeSlug\":\"large\"} -->\n<figure class=\"wp-block-image aligncenter size-large\"><img src=\"https:\/\/www.certisoncology.com\/wp-content\/uploads\/PET-12.2016-e1606781687716.png\" alt=\"PET Scan showing diffuse bony metastasis\" class=\"wp-image-2035\"\/><figcaption class=\"wp-element-caption\">PET Scan, 12\/2016. First recurrence with diffuse bony metastasis and bone marrow involvement (ongoing O-PDX testing)<\/figcaption><\/figure>\n<!-- \/wp:image -->\n\n<!-- wp:paragraph -->\n<p>Rachel\u2019s oncologist, a prominent Sarcoma specialist, treated her with two rounds of vincristine, doxorubicin (Adriamycin), and cyclophosphamide (VDC)\u2014the first-line standard of care for Ewings tumors. Several weeks later, she underwent surgery, removing pieces of rib bone, abdominal wall muscle and diaphragm. Certis orthotopically engrafted this tissue in immunocompromised mice, creating O-PDX replicates of Rachel\u2019s cancer in preparation for a pharmacology study.<\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:paragraph -->\n<p>The post-surgical pathology report indicated treatment with VDC had regressed Rachel\u2019s tumors by 10% and that no cancer cells were found at the edge of the tissue (typically reported in medical terms as \u201cnegative margins\u201d). Encouraged by this news, her oncologist recommended 12 cycles of VDC in combination with iFOSFamide, Etoposide, (VDC\/IE). Seven months passed. A follow-up PET scan showed no evidence of disease. Rachel and her family were elated!<\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:paragraph -->\n<p>Simultaneous to Rachel\u2019s treatment, Certis scientists had completed Rachel\u2019s pharmacology study. The results raised concerns about drug resistance, as her O-PDX models had stopped responding to doxorubicin. But the study also gave insight into Rachel\u2019s possible next line of treatment, as her mice also showed sensitivity to CDK4\/6 and IGF-IR inhibitors.<\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:image {\"align\":\"center\",\"id\":2039,\"sizeSlug\":\"large\"} -->\n<figure class=\"wp-block-image aligncenter size-large\"><img src=\"https:\/\/www.certisoncology.com\/wp-content\/uploads\/Tumor-Volume-over-Time-960x637.png\" alt=\"Study Results-Compassionate Use of IGF-1R Inhibitor\" class=\"wp-image-2039\"\/><figcaption class=\"wp-element-caption\">First round of drug testing in an O-PDX model reveals doxorubicin resistance<\/figcaption><\/figure>\n<!-- \/wp:image -->\n\n<!-- wp:paragraph -->\n<p>In December 2016, Rachel again became ill, and a follow-up MRI confirmed that her aggressive cancer had returned and metastasized throughout her skeletal system, leading to severe cytopenia, a condition marked by deficiency of mature blood cells. Rachel\u2019s oncologist drew on data from the O-PDX pharmacology study completed several months before, which showed sensitivity to other types of drugs. He used this data to request compassionate use of an IGF-IR inhibitor, ganiturnab. <\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:paragraph -->\n<p>As Rachel underwent treatment, Certis initiated a second O-PDX study, orthotopically engrafting fresh tumor tissue into a new group of mice. Her oncologist introduced four new test therapies in this second study. In four of the five arms, Rachel\u2019s tumors grew rapidly. But one therapy--a combination of irinotecan and temozolomide\u2014showed a significant reduction in tumor volume. This was all Rachel and her oncologist needed to move forward with certainty. Rachel began treatment in May 2017, and just as her mouse avatars had done, she responded very positively to irinotecan\/temozolomide in the months ahead.<\/p>\n<!-- \/wp:paragraph -->\n\n<!-- wp:paragraph -->\n<p><em>Elliott IA, Russell TA, Graham D, K Miyake, JG Crompton, Eckardt MA, Brackert S, Federman NC, Yanagawa J, Chmielowski BC, Hoffman RM, Eilber FC, Singh AS<\/em><\/p>\n<!-- \/wp:paragraph -->","post_title":"O-PDX Pharmacology Study Predicts Drug Resistance, Leads to Compassionate Use of IGF-IR Inhibitor","post_excerpt":"<p>O-PDX technique demonstrates condordance in a 46 year-old female diagnosed with rare Ewing\u2019s Sarcoma. Certis Oncology Intelligence can predict drug resistance and improve patient outcomes.<\/p>\n","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"orthotopic-pdx-technique-demonstrates-concordance","to_ping":"","pinged":"","post_modified":"2023-05-15 23:25:26","post_modified_gmt":"2023-05-15 23:25:26","post_content_filtered":"","post_parent":0,"guid":"http:\/\/certisoncology.com\/?post_type=type-cl-results&p=1600","menu_order":0,"post_type":"type-cl-results","post_mime_type":"","comment_count":"0","filter":"raw","permalink":"https:\/\/www.certisoncology.com\/clinical-results\/orthotopic-pdx-technique-demonstrates-concordance\/"}]}"></component-5f8f34d69d36a> </div> <footer> <div class="container"> <div class="d-flex flex-wrap flex-md-nowrap"> <div class="mb-4 mb-md-2 mb-lg-0 mr-sm-4"> <figure class="mb-3 mr-lg-6"> <img class="img-fluid d-block" src="/wp-content/themes/certis/images/certis-logo-lockup-white.svg"> </figure> <address> <div> <span class="street-address d-block">5626 Oberlin Drive, Suite 110</span> <span class="city state zip d-block mb-3">San Diego, CA 92121</span> </div> <div> <span class="phone d-block">Drug Development: 858-988-1033</span> <span class="phone d-block">Patients & Oncologists: 858-228-4110</span> <span class="phone d-block">Main: 858-952-1820</span> </div> </address> </div> <nav class="flex-grow-1"> <ul class="sections ml-0 ml-md-4"> <li> <h4 style="text-transform: uppercase;">Drug Developers</h4> <ul class="child-pages"> <li><a href="https://www.certisoncology.com/for-drug-developers/predictive-oncology-intelligence/">CertisAI™</a></li> <li><a href="https://www.certisoncology.com/for-drug-developers/cancer-models-preclinical-studies/">Cancer Models</a></li> <li><a href="https://www.certisoncology.com/for-drug-developers/custom-model-development/">Custom Model Development</a></li> <li><a href="https://www.certisoncology.com/for-drug-developers/in-vitro-ex-vivo-pharmacology/">In Vitro/Ex Vivo Pharmacology</a></li> <li><a href="https://www.certisoncology.com/for-drug-developers/in-vivo-pharmacology/">In Vivo Pharmacology</a></li> <li><a href="https://www.certisoncology.com/for-drug-developers/imaging-endpoint-analysis/">Imaging/Endpoint Analysis</a></li> <li><a href="https://www.certisoncology.com/for-drug-developers/immuno-oncology/">Immuno-Oncology</a></li> </ul> </li> <li> <h4 style="text-transform: uppercase;">Oncologists</h4> <ul class="child-pages"> <li><a href="https://www.certisoncology.com/for-oncologists/order-yourpdx/">Order YourPDX<sup>®</sup></a></li> <li><a href="https://www.certisoncology.com/for-oncologists/clinical-research/">Clinical Research</a></li> <li><a href="https://www.certisoncology.com/for-oncologists/patient-education/">Patient Education</a></li> </ul> </li> <li> <h4 style="text-transform: uppercase;">Resource Library</h4> <ul class="child-pages"> <li><a href="https://www.certisoncology.com/resources/cancer-market-facts/">Cancer Facts</a></li> <li><a href="https://www.certisoncology.com/resources/clinical-results/">Clinical Results</a></li> <li><a href="https://www.certisoncology.com/resources/supporting-research/">Supporting Research</a></li> <li><a href="https://www.certisoncology.com/resources/media/">Media</a></li> <li><a href="https://whitepapers.certisoncology.com/">White Papers</a></li> </ul> </li> <li> <h4 style="text-transform: uppercase;">About</h4> <ul class="child-pages"> <li><a href="https://www.certisoncology.com/about-us/mission-vision-values/">Mission, Vision & Values</a></li> <li><a href="https://www.certisoncology.com/about-us/our-team/">Team</a></li> <li><a href="https://www.certisoncology.com/about-us/our-story/">Our Story</a></li> <li><a href="https://www.certisoncology.com/about-us/careers/">Careers</a></li> <li><a href="https://www.certisoncology.com/about-us/news/">Company News</a></li> <li><a href="https://www.certisoncology.com/contact-us/">Contact Us</a></li> <li><a href="https://oncointel.certisoncology.com/">Login</a></li> <li><a href="https://www.certisoncology.com/privacy-policy/">Privacy Policy</a></li> </ul> </li> </ul> </nav> </div> <div class="d-flex justify-content-between align-items-end mt-2"> <div class="social-media icons"> <ul> <li><a href="https://www.facebook.com/CertisOncology" target="_blank" class="facebook"></a></li> <li><a href="https://www.linkedin.com/company/certis-oncology" target="_blank" class="linkedin"></a></li> <li><a href="https://twitter.com/CertisOncology" target="_blank" class="twitter"></a></li> <li><a href="https://www.instagram.com/certis_oncology" target="_blank" class="instagram"></a></li> <li><a href="https://www.youtube.com/channel/UCeX4_jh3RlNKxQxZ89_utjg" target="_blank" class="youtube"></a></li> <li><a href="https://blog.certisoncology.com/" target="_blank" class="blog"></a></li> </ul> </div> <div class="d-flex justify-content-end"> <figure class="mouse mx-auto"> <img class="img-fluid d-block" src="/wp-content/themes/certis/images/certis-footer-mouse.svg"> </figure> </div> </div> <hr /> <div class="row"> <div class="col"> <div class="copyright mb-2 mb-sm-0"> <span class="d-block">©2024 Certis Oncology Solutions. All rights reserved.</span> <span class="font-italic">Testimonials appearing on this site reflect real-life experiences of those who have used our services. To protect their privacy, photos feature models.</span> </div> </div> </div> </div> </footer> <cookie-consent :content=""<p>We may use \u201ccookies,\u201d log files, clear gifs or other technologies to help personalize your online experience. For example, a cookie can help us to recall your specific information on subsequent visits. Other technologies allow us to determine which email subscribers click through and read our newsletters. For more information see our <a href=\"\/privacy-policy\/\">Privacy Policy and <\/a><a href=\"\/privacy-policy\/#cookie-statement\">Cookie Statement<\/a><a href=\"\/privacy-policy\/\">.<\/a><\/p>\n""></cookie-consent> </div><!-- end vue app --> <!-- app --> <script crossorigin="anonymous" src="https://polyfill.io/v3/polyfill.min.js?features=es6%2Ces5%2CURL%2Ces7"></script> <script src="https://maps.googleapis.com/maps/api/js?key=AIzaSyCO3sLhHX6ZWiN5jQAYrGQk_7nXYBhBJac"></script> <script src="/wp-content/themes/certis/dist/js/app.js?v2"></script> </body> </html>