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Advancing discovery, medicine and health | Donnelly Centre for Cellular and Biomolecular Research

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srcset="/sites/default/files/styles/masthead_crop_to_right_900_650_1x/public/assets/layout_page/banner_img/Donnelly%20Centre%20and%20CN%20Tower_cropped%20for%20homepage_0.jpg?h=a9a7ed8e&amp;itok=kG1gJ3md 1x" media="(min-width: 0px)" type="image/jpeg" width="900" height="650"/> <img loading="lazy" src="/sites/default/files/styles/masthead_crop_to_right_1200_800_1x/public/assets/layout_page/banner_img/Donnelly%20Centre%20and%20CN%20Tower_cropped%20for%20homepage_0.jpg?h=a9a7ed8e&amp;itok=LrqOdSkK" width="1200" height="700" alt="donnelly centre building" typeof="foaf:Image" /> </picture> </div> <div class="m-banner--overlay__content-wrapper"> <div class="m-banner--overlay__content-width-limiter"> <div class="m-banner--overlay__title-wrapper " > <h1 class="a-heading__t1--overlay " > Advancing discovery, medicine and health </h1> </div> </div> </div> </div> </div> </div> <div class="l-main__utility"> <div data-drupal-messages-fallback class="hidden"></div> </div> <div class="ed-layout-section"> <div class="l-section-bg--white l-section-1--|1-zone| l-section-spacing-top--standard l-section-spacing-bottom--standard"> <div class="l-section-1--|1-zone|__zone-1 l-flex--2col " > <div class="paragraph--published"> <blockquote class="m-quote m-quote--highlight"> <div class="m-quote__text-wrapper--highlight"> <div class="m-quote__body--highlight"> <div class="s-wysiwyg">Donnelly Centre is a global&nbsp;research hub where scientists from diverse fields explore the power of genomic technology to advance discovery, medicine and health.</div> </div> </div> </blockquote> </div> <div class="paragraph--published"> <figure class="m-image"> <div class="m-image-wrap width--100"> <div class="a-duotone--white-teal"> <picture> <source srcset="/sites/default/files/styles/landscape_4_3_400/public/assets/images/hairball%20inversed_greyed_landscape.webp?itok=g4p9LQNW 400w, /sites/default/files/styles/landscape_4_3_600/public/assets/images/hairball%20inversed_greyed_landscape.webp?itok=j-pxmSPu 600w, /sites/default/files/styles/landscape_4_3_900/public/assets/images/hairball%20inversed_greyed_landscape.webp?itok=j5In8Ira 900w, /sites/default/files/styles/landscape_4_3_1200/public/assets/images/hairball%20inversed_greyed_landscape.webp?itok=nPNXwQ-_ 1200w, /sites/default/files/styles/landscape_4_3_1500/public/assets/images/hairball%20inversed_greyed_landscape.webp?itok=ji1T86Fg 1500w, /sites/default/files/styles/landscape_4_3_1800/public/assets/images/hairball%20inversed_greyed_landscape.webp?itok=WPradOc5 1800w" type="image/webp" sizes="(min-width:1280px) 820px, (min-width:900px) 70vw, 100vw - 48px" width="900" height="675"/> <source srcset="/sites/default/files/styles/landscape_4_3_400/public/assets/images/hairball%20inversed_greyed_landscape.jpg?itok=g4p9LQNW 400w, /sites/default/files/styles/landscape_4_3_600/public/assets/images/hairball%20inversed_greyed_landscape.jpg?itok=j-pxmSPu 600w, /sites/default/files/styles/landscape_4_3_900/public/assets/images/hairball%20inversed_greyed_landscape.jpg?itok=j5In8Ira 900w, /sites/default/files/styles/landscape_4_3_1200/public/assets/images/hairball%20inversed_greyed_landscape.jpg?itok=nPNXwQ-_ 1200w, /sites/default/files/styles/landscape_4_3_1500/public/assets/images/hairball%20inversed_greyed_landscape.jpg?itok=ji1T86Fg 1500w, /sites/default/files/styles/landscape_4_3_1800/public/assets/images/hairball%20inversed_greyed_landscape.jpg?itok=WPradOc5 1800w" type="image/jpeg" sizes="(min-width:1280px) 820px, (min-width:900px) 70vw, 100vw - 48px" width="900" height="675"/> <img width="900" height="675" srcset="/sites/default/files/styles/landscape_4_3_400/public/assets/images/hairball%20inversed_greyed_landscape.jpg?itok=g4p9LQNW 400w, /sites/default/files/styles/landscape_4_3_600/public/assets/images/hairball%20inversed_greyed_landscape.jpg?itok=j-pxmSPu 600w, /sites/default/files/styles/landscape_4_3_900/public/assets/images/hairball%20inversed_greyed_landscape.jpg?itok=j5In8Ira 900w, /sites/default/files/styles/landscape_4_3_1200/public/assets/images/hairball%20inversed_greyed_landscape.jpg?itok=nPNXwQ-_ 1200w, /sites/default/files/styles/landscape_4_3_1500/public/assets/images/hairball%20inversed_greyed_landscape.jpg?itok=ji1T86Fg 1500w, /sites/default/files/styles/landscape_4_3_1800/public/assets/images/hairball%20inversed_greyed_landscape.jpg?itok=WPradOc5 1800w" sizes="(min-width:1280px) 820px, (min-width:900px) 70vw, 100vw - 48px" src="/sites/default/files/styles/landscape_4_3_1800/public/assets/images/hairball%20inversed_greyed_landscape.jpg?itok=WPradOc5" alt="map of genetic interactions" loading="lazy" typeof="foaf:Image" /> </picture> </div> <span class="m-image__credit"> Michael Costanzo </span> </div> <figcaption class="m-image__caption"> <div class="m-caption-wrap width--100"> A global map of genetic interactions showing how thousands of genes work together to sustain cellular fitness. </div> </figcaption> </figure> </div> </div> </div> </div> <div class="ed-layout-section"> <div class="l-section-bg--white l-section-1--|1-zone--8| l-section-spacing-top--standard l-section-spacing-bottom--standard"> <div class="l-section-1--|1-zone--8|__zone-1 l-flex " > </div> </div> </div> <div class="ed-layout-section"> <div class="l-section-bg--grey-light l-section-1--|1-zone--8| l-section-spacing-top--standard l-section-spacing-bottom--standard"> <div class="l-section-1--|1-zone--8|__zone-1 l-flex " > </div> </div> </div> <div class="ed-layout-section"> <div class="l-section-bg--white l-section-1--|1-zone| l-section-spacing-top--standard l-section-spacing-bottom--standard"> <div class="l-section-1--|1-zone|__zone-1 l-flex " > <div class="paragraph--published"> <div id="2050"> <div> <div 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<img loading="lazy" srcset="/sites/default/files/styles/landscape_3_2_200/public/assets/news/image/CRC2024fallBME-1155x770.jpg?itok=PnEICk3s 200w, /sites/default/files/styles/landscape_3_2_400/public/assets/news/image/CRC2024fallBME-1155x770.jpg?itok=7YW4Q6Ki 400w, /sites/default/files/styles/landscape_3_2_600/public/assets/news/image/CRC2024fallBME-1155x770.jpg?itok=Wc9NNTbP 600w, /sites/default/files/styles/landscape_3_2_860/public/assets/news/image/CRC2024fallBME-1155x770.jpg?itok=OfCAPUFp 900w, /sites/default/files/styles/landscape_3_2_1200/public/assets/news/image/CRC2024fallBME-1155x770.jpg?itok=q3jybyOi 1200w, /sites/default/files/styles/landscape_3_2_1500/public/assets/news/image/CRC2024fallBME-1155x770.jpg?itok=d_oZVl57 1500w, /sites/default/files/styles/landscape_3_2_1800/public/assets/news/image/CRC2024fallBME-1155x770.jpg?itok=E31AfLZ5 1800w, /sites/default/files/styles/landscape_3_2_2000/public/assets/news/image/CRC2024fallBME-1155x770.jpg?itok=j2nFhy3l 2000w, /sites/default/files/styles/landscape_3_2_2500/public/assets/news/image/CRC2024fallBME-1155x770.jpg?itok=Gew88ZnR 2500w, /sites/default/files/styles/landscape_3_2_2800/public/assets/news/image/CRC2024fallBME-1155x770.jpg?itok=noNAXSe- 2800w, /sites/default/files/styles/landscape_3_2_3000/public/assets/news/image/CRC2024fallBME-1155x770.jpg?itok=0qJH1M83 3000w" sizes="(min-width:1280px) 372px, (min-width:900px) 33vw - 40px, (min-width:600px) 50vw - 40px, 100vw - 40px" width="900" height="600" src="/sites/default/files/styles/landscape_3_2_600/public/assets/news/image/CRC2024fallBME-1155x770.jpg?itok=Wc9NNTbP" alt="Headshots of Michael Garton, Azadeh Kushki and Warren Chan" typeof="foaf:Image" /> </picture> </a> <div class="m-card__main"> <div class="m-card__date"> <span class="a-date"> <span class="a-date__start"> Nov 20, 2024 </span> </span> </div> <div class="m-card__title"> <h2 class="a-heading__h3 has-link " > <a href="/news/three-u-t-biomedical-engineers-awarded-canada-research-chairs-innovations-synthetic-biology" id="card-nid-1567" > Three U of T biomedical engineers awarded Canada Research Chairs for innovations in synthetic biology, neurodiversity health, and nanobioengineering <span class="a-heading__last-word"> <svg class="a-heading__icon"> <use xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="/themes/webpac/assets/svg/sprite-ui.svg#ico-chevron-right"> </use> </svg> </span> </a> </h2> </div> <div class="m-card__body s-wysiwyg"> Three faculty members at the University of Toronto鈥檚 Institute of Biomedical Engineering (BME) have been awarded Canada Research Chairs (CRCs) by the Canadian Institutes of Health Research (CIHR) and the Natural Sciences and Engineering Research Council (NSERC). Professors Michael Garton, Azadeh Kushki, and Warren Chan have each received CRC funding to drive forward-thinking research in synthetic biology, personalized neurodevelopmental health, and nanotechnology. </div> </div> </div> <div class="m-card u-shadow__box--focus contextual-region"> <a href="/news/professor-milica-radisic-earns-nsercs-john-c-polanyi-award" class="m-card__banner--link" aria-labelledby="card-nid-1555" aria-hidden="true" tabindex="-1"> <picture> <source srcset="/sites/default/files/styles/landscape_3_2_200/public/assets/news/image/1A4A4423_1500x1000.webp?itok=T7HqCxcw 200w, /sites/default/files/styles/landscape_3_2_400/public/assets/news/image/1A4A4423_1500x1000.webp?itok=bFgk4T0Z 400w, /sites/default/files/styles/landscape_3_2_600/public/assets/news/image/1A4A4423_1500x1000.webp?itok=1tA6eVLE 600w, /sites/default/files/styles/landscape_3_2_860/public/assets/news/image/1A4A4423_1500x1000.webp?itok=Q-UcBwBz 900w, /sites/default/files/styles/landscape_3_2_1200/public/assets/news/image/1A4A4423_1500x1000.webp?itok=bTR_k_vp 1200w, /sites/default/files/styles/landscape_3_2_1500/public/assets/news/image/1A4A4423_1500x1000.webp?itok=zi0FD3xr 1500w, /sites/default/files/styles/landscape_3_2_1800/public/assets/news/image/1A4A4423_1500x1000.webp?itok=_-oe79M_ 1800w, /sites/default/files/styles/landscape_3_2_2000/public/assets/news/image/1A4A4423_1500x1000.webp?itok=Mhod9xOm 2000w, /sites/default/files/styles/landscape_3_2_2500/public/assets/news/image/1A4A4423_1500x1000.webp?itok=IiJaTJB3 2500w, /sites/default/files/styles/landscape_3_2_2800/public/assets/news/image/1A4A4423_1500x1000.webp?itok=WjTeyW68 2800w, /sites/default/files/styles/landscape_3_2_3000/public/assets/news/image/1A4A4423_1500x1000.webp?itok=Ypp_Q2rX 3000w" type="image/webp" sizes="(min-width:1280px) 372px, (min-width:900px) 33vw - 40px, (min-width:600px) 50vw - 40px, 100vw - 40px" width="900" height="600"/> <source srcset="/sites/default/files/styles/landscape_3_2_200/public/assets/news/image/1A4A4423_1500x1000.jpg?itok=T7HqCxcw 200w, /sites/default/files/styles/landscape_3_2_400/public/assets/news/image/1A4A4423_1500x1000.jpg?itok=bFgk4T0Z 400w, /sites/default/files/styles/landscape_3_2_600/public/assets/news/image/1A4A4423_1500x1000.jpg?itok=1tA6eVLE 600w, /sites/default/files/styles/landscape_3_2_860/public/assets/news/image/1A4A4423_1500x1000.jpg?itok=Q-UcBwBz 900w, /sites/default/files/styles/landscape_3_2_1200/public/assets/news/image/1A4A4423_1500x1000.jpg?itok=bTR_k_vp 1200w, /sites/default/files/styles/landscape_3_2_1500/public/assets/news/image/1A4A4423_1500x1000.jpg?itok=zi0FD3xr 1500w, /sites/default/files/styles/landscape_3_2_1800/public/assets/news/image/1A4A4423_1500x1000.jpg?itok=_-oe79M_ 1800w, /sites/default/files/styles/landscape_3_2_2000/public/assets/news/image/1A4A4423_1500x1000.jpg?itok=Mhod9xOm 2000w, /sites/default/files/styles/landscape_3_2_2500/public/assets/news/image/1A4A4423_1500x1000.jpg?itok=IiJaTJB3 2500w, /sites/default/files/styles/landscape_3_2_2800/public/assets/news/image/1A4A4423_1500x1000.jpg?itok=WjTeyW68 2800w, /sites/default/files/styles/landscape_3_2_3000/public/assets/news/image/1A4A4423_1500x1000.jpg?itok=Ypp_Q2rX 3000w" type="image/jpeg" sizes="(min-width:1280px) 372px, (min-width:900px) 33vw - 40px, (min-width:600px) 50vw - 40px, 100vw - 40px" width="900" height="600"/> <img loading="lazy" srcset="/sites/default/files/styles/landscape_3_2_200/public/assets/news/image/1A4A4423_1500x1000.jpg?itok=T7HqCxcw 200w, /sites/default/files/styles/landscape_3_2_400/public/assets/news/image/1A4A4423_1500x1000.jpg?itok=bFgk4T0Z 400w, /sites/default/files/styles/landscape_3_2_600/public/assets/news/image/1A4A4423_1500x1000.jpg?itok=1tA6eVLE 600w, /sites/default/files/styles/landscape_3_2_860/public/assets/news/image/1A4A4423_1500x1000.jpg?itok=Q-UcBwBz 900w, /sites/default/files/styles/landscape_3_2_1200/public/assets/news/image/1A4A4423_1500x1000.jpg?itok=bTR_k_vp 1200w, /sites/default/files/styles/landscape_3_2_1500/public/assets/news/image/1A4A4423_1500x1000.jpg?itok=zi0FD3xr 1500w, /sites/default/files/styles/landscape_3_2_1800/public/assets/news/image/1A4A4423_1500x1000.jpg?itok=_-oe79M_ 1800w, /sites/default/files/styles/landscape_3_2_2000/public/assets/news/image/1A4A4423_1500x1000.jpg?itok=Mhod9xOm 2000w, /sites/default/files/styles/landscape_3_2_2500/public/assets/news/image/1A4A4423_1500x1000.jpg?itok=IiJaTJB3 2500w, /sites/default/files/styles/landscape_3_2_2800/public/assets/news/image/1A4A4423_1500x1000.jpg?itok=WjTeyW68 2800w, /sites/default/files/styles/landscape_3_2_3000/public/assets/news/image/1A4A4423_1500x1000.jpg?itok=Ypp_Q2rX 3000w" sizes="(min-width:1280px) 372px, (min-width:900px) 33vw - 40px, (min-width:600px) 50vw - 40px, 100vw - 40px" width="900" height="600" src="/sites/default/files/styles/landscape_3_2_600/public/assets/news/image/1A4A4423_1500x1000.jpg?itok=1tA6eVLE" alt="Milica Radisic standing inside glass building" typeof="foaf:Image" /> </picture> </a> <div class="m-card__main"> <div class="m-card__date"> <span class="a-date"> <span class="a-date__start"> Nov 6, 2024 </span> </span> </div> <div class="m-card__title"> <h2 class="a-heading__h3 has-link " > <a href="/news/professor-milica-radisic-earns-nsercs-john-c-polanyi-award" id="card-nid-1555" > Professor Milica Radisic earns NSERC鈥檚 John C. Polanyi <span class="a-heading__last-word">Award <svg class="a-heading__icon"> <use xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="/themes/webpac/assets/svg/sprite-ui.svg#ico-chevron-right"> </use> </svg> </span> </a> </h2> </div> <div class="m-card__body s-wysiwyg"> Professor&nbsp;<strong>Milica Radisic</strong>&nbsp;(BME, ChemE) has received this year鈥檚 John C. Polanyi Award from the Natural Sciences and Engineering Research Council (NSERC). </div> </div> </div> <div class="m-card u-shadow__box--focus contextual-region"> <a href="/news/researchers-home-tumour-vulnerabilities-improve-odds-treating-glioblastoma" class="m-card__banner--link" aria-labelledby="card-nid-1552" aria-hidden="true" tabindex="-1"> <picture> <source srcset="/sites/default/files/styles/landscape_3_2_200/public/assets/news/image/MacLeod_Molaei_Angers.webp?itok=Yx18VTZN 200w, /sites/default/files/styles/landscape_3_2_400/public/assets/news/image/MacLeod_Molaei_Angers.webp?itok=0sbJjz_q 400w, /sites/default/files/styles/landscape_3_2_600/public/assets/news/image/MacLeod_Molaei_Angers.webp?itok=fOQ-becm 600w, /sites/default/files/styles/landscape_3_2_860/public/assets/news/image/MacLeod_Molaei_Angers.webp?itok=SSgm0Kbe 900w, /sites/default/files/styles/landscape_3_2_1200/public/assets/news/image/MacLeod_Molaei_Angers.webp?itok=kS7vFku_ 1200w, /sites/default/files/styles/landscape_3_2_1500/public/assets/news/image/MacLeod_Molaei_Angers.webp?itok=ummPxXBX 1500w, /sites/default/files/styles/landscape_3_2_1800/public/assets/news/image/MacLeod_Molaei_Angers.webp?itok=5xaqJAoF 1800w, /sites/default/files/styles/landscape_3_2_2000/public/assets/news/image/MacLeod_Molaei_Angers.webp?itok=83YGoNrW 2000w, /sites/default/files/styles/landscape_3_2_2500/public/assets/news/image/MacLeod_Molaei_Angers.webp?itok=vDwOg5wQ 2500w, /sites/default/files/styles/landscape_3_2_2800/public/assets/news/image/MacLeod_Molaei_Angers.webp?itok=2bdDyFa9 2800w, /sites/default/files/styles/landscape_3_2_3000/public/assets/news/image/MacLeod_Molaei_Angers.webp?itok=xqAx-N8f 3000w" type="image/webp" sizes="(min-width:1280px) 372px, (min-width:900px) 33vw - 40px, (min-width:600px) 50vw - 40px, 100vw - 40px" width="900" height="600"/> <source srcset="/sites/default/files/styles/landscape_3_2_200/public/assets/news/image/MacLeod_Molaei_Angers.jpg?itok=Yx18VTZN 200w, /sites/default/files/styles/landscape_3_2_400/public/assets/news/image/MacLeod_Molaei_Angers.jpg?itok=0sbJjz_q 400w, /sites/default/files/styles/landscape_3_2_600/public/assets/news/image/MacLeod_Molaei_Angers.jpg?itok=fOQ-becm 600w, /sites/default/files/styles/landscape_3_2_860/public/assets/news/image/MacLeod_Molaei_Angers.jpg?itok=SSgm0Kbe 900w, /sites/default/files/styles/landscape_3_2_1200/public/assets/news/image/MacLeod_Molaei_Angers.jpg?itok=kS7vFku_ 1200w, /sites/default/files/styles/landscape_3_2_1500/public/assets/news/image/MacLeod_Molaei_Angers.jpg?itok=ummPxXBX 1500w, /sites/default/files/styles/landscape_3_2_1800/public/assets/news/image/MacLeod_Molaei_Angers.jpg?itok=5xaqJAoF 1800w, /sites/default/files/styles/landscape_3_2_2000/public/assets/news/image/MacLeod_Molaei_Angers.jpg?itok=83YGoNrW 2000w, /sites/default/files/styles/landscape_3_2_2500/public/assets/news/image/MacLeod_Molaei_Angers.jpg?itok=vDwOg5wQ 2500w, /sites/default/files/styles/landscape_3_2_2800/public/assets/news/image/MacLeod_Molaei_Angers.jpg?itok=2bdDyFa9 2800w, /sites/default/files/styles/landscape_3_2_3000/public/assets/news/image/MacLeod_Molaei_Angers.jpg?itok=xqAx-N8f 3000w" type="image/jpeg" sizes="(min-width:1280px) 372px, (min-width:900px) 33vw - 40px, (min-width:600px) 50vw - 40px, 100vw - 40px" width="900" height="600"/> <img loading="lazy" srcset="/sites/default/files/styles/landscape_3_2_200/public/assets/news/image/MacLeod_Molaei_Angers.jpg?itok=Yx18VTZN 200w, /sites/default/files/styles/landscape_3_2_400/public/assets/news/image/MacLeod_Molaei_Angers.jpg?itok=0sbJjz_q 400w, /sites/default/files/styles/landscape_3_2_600/public/assets/news/image/MacLeod_Molaei_Angers.jpg?itok=fOQ-becm 600w, /sites/default/files/styles/landscape_3_2_860/public/assets/news/image/MacLeod_Molaei_Angers.jpg?itok=SSgm0Kbe 900w, /sites/default/files/styles/landscape_3_2_1200/public/assets/news/image/MacLeod_Molaei_Angers.jpg?itok=kS7vFku_ 1200w, /sites/default/files/styles/landscape_3_2_1500/public/assets/news/image/MacLeod_Molaei_Angers.jpg?itok=ummPxXBX 1500w, /sites/default/files/styles/landscape_3_2_1800/public/assets/news/image/MacLeod_Molaei_Angers.jpg?itok=5xaqJAoF 1800w, /sites/default/files/styles/landscape_3_2_2000/public/assets/news/image/MacLeod_Molaei_Angers.jpg?itok=83YGoNrW 2000w, /sites/default/files/styles/landscape_3_2_2500/public/assets/news/image/MacLeod_Molaei_Angers.jpg?itok=vDwOg5wQ 2500w, /sites/default/files/styles/landscape_3_2_2800/public/assets/news/image/MacLeod_Molaei_Angers.jpg?itok=2bdDyFa9 2800w, /sites/default/files/styles/landscape_3_2_3000/public/assets/news/image/MacLeod_Molaei_Angers.jpg?itok=xqAx-N8f 3000w" sizes="(min-width:1280px) 372px, (min-width:900px) 33vw - 40px, (min-width:600px) 50vw - 40px, 100vw - 40px" width="900" height="600" src="/sites/default/files/styles/landscape_3_2_600/public/assets/news/image/MacLeod_Molaei_Angers.jpg?itok=fOQ-becm" alt="Composite of headshots of Graham MacLeod, Fatemeh Molaei and Stephane Angers" typeof="foaf:Image" /> </picture> </a> <div class="m-card__main"> <div class="m-card__date"> <span class="a-date"> <span class="a-date__start"> Nov 4, 2024 </span> </span> </div> <div class="m-card__title"> <h2 class="a-heading__h3 has-link " > <a href="/news/researchers-home-tumour-vulnerabilities-improve-odds-treating-glioblastoma" id="card-nid-1552" > Researchers home in on tumour vulnerabilities to improve odds of treating <span class="a-heading__last-word">glioblastoma <svg class="a-heading__icon"> <use xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="/themes/webpac/assets/svg/sprite-ui.svg#ico-chevron-right"> </use> </svg> </span> </a> </h2> </div> <div class="m-card__body s-wysiwyg"> A team led by researchers at the University of Toronto has uncovered new targets that could be the key to effectively treating glioblastoma, a lethal type of brain cancer. 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href="https://pubmed.ncbi.nlm.nih.gov/39568440/?utm_source=Other&amp;utm_medium=rss&amp;utm_campaign=pubmed-2&amp;utm_content=1RQQ955biveyjus1jlTwIQvqWKM-3A2BPWAVd6c8OVPdwkY5wk&amp;fc=20220307105038&amp;ff=20241121073827&amp;v=2.18.0.post9%20e462414" id="card-nid-1570" > Acute myeloid leukemia drug tolerant persister cells survive chemotherapy by transiently increasing plasma membrane rigidity, that also increases their sensitivity to immune cell <span class="a-heading__last-word">killing <svg class="a-heading__icon"> <use xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="/themes/webpac/assets/svg/sprite-ui.svg#ico-chevron-right"> </use> </svg> </span> </a> </h2> </div> <div class="m-card--feed-item__journal"> Haematologica </div> <div class="m-card--feed-item__authors"> Yael Morgenstern, JongBok Lee, Yoosu Na, Brandon Y Lieng, Nicholas S L... </div> </div> <div class="m-card--feed-item"> <div class="m-card--feed-item__date"> <span class="a-date"> <span class="a-date__start"> Nov 20, 2024 </span> </span> </div> <div class="m-card--feed-item__title"> <h2 class="a-heading__h3 has-link " > <a href="https://pubmed.ncbi.nlm.nih.gov/39565292/?utm_source=Other&amp;utm_medium=rss&amp;utm_campaign=pubmed-2&amp;utm_content=1zOrwYPa_1RZ6jdKeD1mqTEl4dhic5VVXsDz2YrUyNKqZUt9Fc&amp;fc=20220307105912&amp;ff=20241120124153&amp;v=2.18.0.post9%20e462414" id="card-nid-1568" > A multimodal digital microfluidic testing platform for antibody-producing cell <span class="a-heading__last-word">lines <svg class="a-heading__icon"> <use xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="/themes/webpac/assets/svg/sprite-ui.svg#ico-chevron-right"> </use> </svg> </span> </a> </h2> </div> <div class="m-card--feed-item__journal"> Lab on a chip </div> <div class="m-card--feed-item__authors"> Jeremy T Lant, Jurgen Frasheri, Taehong Kwon, Camille M N Tsang, Bingy... </div> </div> <div class="m-card--feed-item"> <div class="m-card--feed-item__date"> <span class="a-date"> <span class="a-date__start"> Nov 20, 2024 </span> </span> </div> <div class="m-card--feed-item__title"> <h2 class="a-heading__h3 has-link " > <a href="https://pubmed.ncbi.nlm.nih.gov/39567491/?utm_source=Other&amp;utm_medium=rss&amp;utm_campaign=pubmed-2&amp;utm_content=1bCr63ThlO23Eh5HwBjFL02CInvOYXOM5i6V-PmoqexzGtEsx9&amp;fc=20220307103834&amp;ff=20241121013858&amp;v=2.18.0.post9%20e462414" id="card-nid-1569" > The commitment of the human cell atlas to <span class="a-heading__last-word">humanity <svg class="a-heading__icon"> <use xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="/themes/webpac/assets/svg/sprite-ui.svg#ico-chevron-right"> </use> </svg> </span> </a> </h2> </div> <div class="m-card--feed-item__journal"> Nature communications </div> <div class="m-card--feed-item__authors"> Ido Amit, Kristin Ardlie, Fabiana Arzuaga, Gordon Awandare, Gary Bader... </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div class="ed-layout-section"> <div 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(Rafa)</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/faculty/john-morris" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/1410">Morris, John</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/faculty/cindi-morshead" title="" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/253">Morshead, Cindi</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/faculty/milica-radisic" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/1056">Radisic, Milica</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/faculty/hannes-rost" title="" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/266">R枚st, Hannes</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/faculty/frederick-roth" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/255">Roth, Frederick (Fritz)</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/faculty/peter-roy" title="" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/237">Roy, Peter</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/faculty/william-ryu" title="" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/256">Ryu, William</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/faculty/michael-sefton" title="" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/257">Sefton, Michael</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/faculty/molly-shoichet" title="" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/258">Shoichet, Molly</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/faculty/igor-stagljar" title="" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/260">Stagljar, Igor</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/faculty/mikko-taipale" title="" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/261">Taipale, Mikko</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/faculty/derek-van-der-kooy" title="" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/250">van der Kooy, Derek</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/faculty/shu-wang" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/1346">Wang, Shu</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/faculty/aaron-wheeler" title="" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/262">Wheeler, Aaron</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/faculty/christopher-yip" title="" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/263">Yip, Christopher</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/faculty/zhaolei-zhang" title="" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/265">Zhang, Zhaolei</a> </li> </ul> </li> <li class="menu-firstchild m-menu-mobile__item--level-1 has-submenu"> <a href="/our-research-0" class="m-menu-mobile__link--level-1 is-toggle">Research</a> <ul class="m-menu-mobile__list--level-2"> <li class="m-menu-mobile__item--level-2"> <a href="/our-research-0" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/411">Our Research</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/pubmed" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/383">Publications (RSS feed)</a> </li> </ul> </li> <li class="m-menu-mobile__item--level-1 has-submenu"> <a href="/platforms" class="m-menu-mobile__link--level-1 is-toggle" data-drupal-link-system-path="node/402">Platforms</a> <ul class="m-menu-mobile__list--level-2"> <li class="m-menu-mobile__item--level-2"> <a href="/accelerator-donnelly-collaboration" title="" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/376">Accelerator for Donnelly Collaboration</a> </li> <li class="m-menu-mobile__item--level-2 has-submenu"> <a href="/donnelly-sequencing-centre" class="m-menu-mobile__link--level-2 is-toggle" data-drupal-link-system-path="node/307">Donnelly Sequencing Centre</a> <ul class="m-menu-mobile__list--level-3"> <li class="m-menu-mobile__item--level-3"> <a href="/what-we-offer" class="m-menu-mobile__link--level-3" data-drupal-link-system-path="node/365">What We Offer</a> </li> <li class="m-menu-mobile__item--level-3"> <a href="/getting-started" class="m-menu-mobile__link--level-3" data-drupal-link-system-path="node/366">Getting Started</a> </li> <li class="m-menu-mobile__item--level-3"> <a href="/dsc-team" class="m-menu-mobile__link--level-3" data-drupal-link-system-path="node/367">The DSC Team</a> </li> <li class="m-menu-mobile__item--level-3"> <a href="/selected-publications" class="m-menu-mobile__link--level-3" data-drupal-link-system-path="node/368">Publications</a> </li> <li class="m-menu-mobile__item--level-3"> <a href="/academic-outreach" class="m-menu-mobile__link--level-3" data-drupal-link-system-path="node/369">Academic Outreach</a> </li> <li class="m-menu-mobile__item--level-3"> <a href="/world-sequencing" class="m-menu-mobile__link--level-3" data-drupal-link-system-path="node/371">The World of Sequencing</a> </li> </ul> </li> <li class="m-menu-mobile__item--level-2"> <a href="/donnelly-mass-spec-facility" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/364">Donnelly Mass Spec Facility</a> </li> </ul> </li> <li class="m-menu-mobile__item--level-1 has-submenu"> <a href="/students" class="m-menu-mobile__link--level-1 is-toggle" data-drupal-link-system-path="node/401">Students</a> <ul class="m-menu-mobile__list--level-2"> <li class="m-menu-mobile__item--level-2 has-submenu"> <a href="/student-awards" class="m-menu-mobile__link--level-2 is-toggle" data-drupal-link-system-path="node/294">Student Awards</a> <ul class="m-menu-mobile__list--level-3"> <li class="m-menu-mobile__item--level-3"> <a href="/cecil-yip-doctoral-research-award" class="m-menu-mobile__link--level-3" data-drupal-link-system-path="node/297">Cecil Yip Doctoral Research Award</a> </li> <li class="m-menu-mobile__item--level-3"> <a href="/donnelly-centre-research-thesis-prize" class="m-menu-mobile__link--level-3" data-drupal-link-system-path="node/298">Donnelly Centre Research Thesis Prize</a> </li> <li class="m-menu-mobile__item--level-3"> <a href="/jennifer-comyn-graduate-award-cancer-research" class="m-menu-mobile__link--level-3" data-drupal-link-system-path="node/1244">Jennifer Comyn Graduate Award for Cancer Research</a> </li> <li class="m-menu-mobile__item--level-3"> <a href="/jennifer-dorrington-graduate-research-award" class="m-menu-mobile__link--level-3" data-drupal-link-system-path="node/296">Jennifer Dorrington Graduate Research Award</a> </li> </ul> </li> <li class="m-menu-mobile__item--level-2"> <a href="/donnelly-centre-graduate-student-association" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/326">Donnelly Centre Graduate Student Association</a> </li> <li class="m-menu-mobile__item--level-2 has-submenu"> <a href="/summer-undergraduate-research-program" class="m-menu-mobile__link--level-2 is-toggle" data-drupal-link-system-path="node/355">Summer Undergraduate Research Program</a> <ul class="m-menu-mobile__list--level-3"> <li class="m-menu-mobile__item--level-3"> <a href="/donnelly-centre-summer-student-research-award" class="m-menu-mobile__link--level-3" data-drupal-link-system-path="node/1358">Donnelly Centre Summer Student Research Award</a> </li> </ul> </li> </ul> </li> <li class="m-menu-mobile__item--level-1 has-submenu"> <a href="/postdocs" class="m-menu-mobile__link--level-1 is-toggle" data-drupal-link-system-path="node/403">Postdocs</a> <ul class="m-menu-mobile__list--level-2"> <li class="m-menu-mobile__item--level-2"> <a href="/charles-h-best-postdoctoral-fellowship" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/295">Charles H. Best Postdoctoral Fellowship</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/donnelly-centre-home-fellowship" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/1353">Donnelly Centre Home Fellowship</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/donnelly-centre-research-excellence-award" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/356">Donnelly Centre Research Excellence Award</a> </li> </ul> </li> <li class="menu-firstchild m-menu-mobile__item--level-1 has-submenu"> <a href="/news" class="m-menu-mobile__link--level-1 is-toggle">News</a> <ul class="m-menu-mobile__list--level-2"> <li class="m-menu-mobile__item--level-2"> <a href="/news" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/381">News</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/donnelly-centre-magazine" title="" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/374">Donnelly Centre Magazine</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/annual-reports" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/400">Annual Reports</a> </li> <li class="m-menu-mobile__item--level-2 has-submenu"> <a href="/donnelly-media" class="m-menu-mobile__link--level-2 is-toggle" data-drupal-link-system-path="node/316">Donnelly in the Media</a> <ul class="m-menu-mobile__list--level-3"> <li class="m-menu-mobile__item--level-3"> <a href="/media-archive-2008-2020" class="m-menu-mobile__link--level-3" data-drupal-link-system-path="node/426">In the Media Archive (2008-2020)</a> </li> </ul> </li> </ul> </li> <li class="menu-firstchild m-menu-mobile__item--level-1 has-submenu"> <a href="/current-opportunities" class="m-menu-mobile__link--level-1 is-toggle">Careers</a> <ul class="m-menu-mobile__list--level-2"> <li class="m-menu-mobile__item--level-2"> <a href="/current-opportunities" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/283">Current Opportunities</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/working-and-living-toronto" title="" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/299">Working and Living in Toronto</a> </li> </ul> </li> <li class="m-menu-mobile__item--level-1 has-submenu"> <a href="/events" class="m-menu-mobile__link--level-1 is-toggle" data-drupal-link-system-path="node/1249">Events</a> <ul class="m-menu-mobile__list--level-2"> <li class="m-menu-mobile__item--level-2"> <a href="/events" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/1249">Events</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/postdoctoral-fellow-and-research-associate-seminars" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/323">Postdoctoral Fellow and Research Associate Seminars</a> </li> </ul> </li> <li class="menu-firstchild m-menu-mobile__item--level-1 has-submenu"> <a href="/welcome-director" class="m-menu-mobile__link--level-1 is-toggle">About Us</a> <ul class="m-menu-mobile__list--level-2"> <li class="m-menu-mobile__item--level-2"> <a href="/welcome-director" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/455">Director&#039;s Welcome Message</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/terrence-j-donnelly" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/304">Terrence J. Donnelly</a> </li> <li class="m-menu-mobile__item--level-2 has-submenu"> <a href="/built-21st-century-science" class="m-menu-mobile__link--level-2 is-toggle" data-drupal-link-system-path="node/285">History of the Donnelly Centre</a> <ul class="m-menu-mobile__list--level-3"> <li class="m-menu-mobile__item--level-3"> <a href="/banting-and-best-department-medical-research-timeline" class="m-menu-mobile__link--level-3" data-drupal-link-system-path="node/347">Get to know our history through this interactive timeline</a> </li> <li class="m-menu-mobile__item--level-3"> <a href="/banting-and-best-department-medical-research" class="m-menu-mobile__link--level-3" data-drupal-link-system-path="node/344">Banting and Best Department of Medical Research</a> </li> <li class="m-menu-mobile__item--level-3"> <a href="/brenda-andrews-founding-director-donnelly-centre" class="m-menu-mobile__link--level-3" data-drupal-link-system-path="node/476">Brenda Andrews, Founding Director of Donnelly Centre</a> </li> <li class="m-menu-mobile__item--level-3"> <a href="/james-friesen-co-founder-donnelly-centre" class="m-menu-mobile__link--level-3" data-drupal-link-system-path="node/348">James Friesen, Co-Founder of Donnelly Centre</a> </li> <li class="m-menu-mobile__item--level-3"> <a href="/cecil-yip-co-founder-donnelly-centre" class="m-menu-mobile__link--level-3" data-drupal-link-system-path="node/346">Cecil Yip, Co-Founder of Donnelly Centre</a> </li> </ul> </li> <li class="m-menu-mobile__item--level-2"> <a href="/staff" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/305">Staff</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/image-gallery" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/328">Image Gallery</a> </li> <li class="m-menu-mobile__item--level-2"> <a href="/contact-us" class="m-menu-mobile__link--level-2" data-drupal-link-system-path="node/311">Contact Us</a> </li> </ul> </li> <div id="menu-mobile-header-content"> <div class="m-menu-mobile__header-content"> </div> </div> </ul> </nav> </nav> </div> </div> <script>window.dataLayer = window.dataLayer || []; window.dataLayer.push({"drupalLanguage":"en","drupalCountry":null,"siteName":"Donnelly Centre for Cellular and Biomolecular Research","entityName":"administrator","entityType":"node","entityBundle":"ed_layout_page","entityId":"1","entityTitle":"Advancing discovery, medicine and health","userUid":0,"breadcrumbLevel1":"","breadcrumbLevel2":"","breadcrumbLevel3":""});</script> <link rel="stylesheet" href="https://use.typekit.net/zls1oah.css"> <script type="application/json" data-drupal-selector="drupal-settings-json">{"path":{"baseUrl":"\/","pathPrefix":"","currentPath":"node\/1","currentPathIsAdmin":false,"isFront":true,"currentLanguage":"en"},"pluralDelimiter":"\u0003","suppressDeprecationErrors":true,"ajaxPageState":{"libraries":"eJx9kNGqAyEMRH9I9JMkaqpyYyLG7LJ_36VcaOlDX8JhJjCZJAvJfG6Y_3C5DDc9yLSFN_qBbC6bbhkRyugcBnTeyMAZI8vuGdUV2EBw4QoJGxxdlrqH8IYTVQaGD_Z6VJ8WcPm9okK9uCpSCSMw0HVHafgW3IQFdcFsGsqyCeTfijeelqhrw-L00o0jJFB0R8dTw2v6IcUI3YlpQr7PML7bdOFYlswiJ_-w4us9_34lSUBPbviGZw","theme":"webpac","theme_token":null},"ajaxTrustedUrl":[],"bu":{"_core":{"default_config_hash":"AblkqYHezKA1TuKStbuiQqvACikY5ElI-bHxMy-C25U"},"notify_ie":11,"notify_firefox":-2,"notify_opera":-2,"notify_safari":-2,"notify_chrome":-2,"insecure":false,"unsupported":false,"mobile":false,"visibility_type":"hide","visibility_pages":"admin\/*","source":"\/\/browser-update.org\/update.min.js","show_source":"","position":"top","text_override":"","reminder":4380,"reminder_closed":4380,"new_window":true,"url":"","no_close":false,"test_mode":false},"dataLayer":{"defaultLang":"en","languages":{"en":{"id":"en","name":"English","direction":"ltr","weight":0}}},"google_analytics":{"account":"UA-34496632-11","trackOutbound":true,"trackMailto":true,"trackTel":true,"trackDownload":true,"trackDownloadExtensions":"7z|aac|arc|arj|asf|asx|avi|bin|csv|doc(x|m)?|dot(x|m)?|exe|flv|gif|gz|gzip|hqx|jar|jpe?g|js|mp(2|3|4|e?g)|mov(ie)?|msi|msp|pdf|phps|png|ppt(x|m)?|pot(x|m)?|pps(x|m)?|ppam|sld(x|m)?|thmx|qtm?|ra(m|r)?|sea|sit|tar|tgz|torrent|txt|wav|wma|wmv|wpd|xls(x|m|b)?|xlt(x|m)|xlam|xml|z|zip"},"user":{"uid":0,"permissionsHash":"e5117ae9e1952bc666f6f6eded612e9062e3e550f37a6e73234d0ebf81dbff34"}}</script> <script src="/sites/default/files/js/js_vMSEPHDskVi_p9TfdYxNiqFwZ_jUvnuiJNwO6MCW38g.js?scope=footer&amp;delta=0&amp;language=en&amp;theme=webpac&amp;include=eJx9jkEOwyAMBD-E4EnIxg5BdewIQ1B-314qVT3ktjs7h8WZcMayc3lxDwQDBG7uCXmHq1n3sJkOWOx2cPrJ0a8a3aTRo4EdlDxUsyqcQUHu0YqnfxAW4wklVTEE-bbNpn4-NdNM3U6ypQ9TPljnG5FMUo4"></script> </body> </html>

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