Reagents - Lunaphore Technologies

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style="background-image:url('https://lunaphore.com/wp-content/uploads/2023/03/CRC_3-1920x716.jpg')"> <div class="container "> <div class="row "> <div class="col"> <h1 class="display-2 text-white">Reagents</h1> <p class="lead text-white">Tools for spatial biology research.</p> </div> </div> </div> </header>  <section class="section-subheader" > <div class="container"> <div class="row justify-content-lg-between justify-content-center"> <div class="col-lg-12 mt-5 mt-lg-0 mb-3" > <h4 class="h2 mb-4"> Robust and reliable spatial biology data requires trusted reagents. </h4> <div> <p>The journey of scientific discovery and development can be an overwhelming challenge. Streamline and accelerate your research with Lunaphore’s complete product offering, which includes solutions to execute your workflow from A to Z.</p> <p>We offer a wide selection of dedicated reagents for optimal results with our spatial biology platforms. With lot-to-lot consistency and strict quality control testing you can generate highly reproducible data. Choose from the selection below to ensure fast and scalable results.</p> </div> </div> </div> </div> </section>  <section class="section-subheader" > <div class="container"> <div class="row justify-content-lg-between justify-content-center"> <div class="col-lg-5"> <h4 class="h3 mb-4"> Explore spatial context with the right tools </h4> </div> <div class="col-lg-6"> <div class="row mb-5"> <div class="col-lg-12 d-flex align-items-start "> <img class="mr-3" width="30" src="https://lunaphore.com/wp-content/themes/mokatheme/assets/img/checkmark.svg" alt=""> <div class="mb-4"> <h6 class="pt-1"> High-quality reagents with reproducible performance </h6> </div> </div> <div class="col-lg-12 d-flex align-items-start "> <img class="mr-3" width="30" src="https://lunaphore.com/wp-content/themes/mokatheme/assets/img/checkmark.svg" alt=""> <div class="mb-4"> <h6 class="pt-1"> Supported by extensive data </h6> </div> </div> <div class="col-lg-12 d-flex align-items-start "> <img class="mr-3" width="30" src="https://lunaphore.com/wp-content/themes/mokatheme/assets/img/checkmark.svg" alt=""> <div class="mb-4"> <h6 class="pt-1"> Ready-to-use </h6> </div> </div> </div> </div> </div> </div> </section>  <section class="section-subheader" > <div class="container"> <div class="row justify-content-lg-between justify-content-center"> <div class="col-lg-12 mt-5 mt-lg-0 mb-3" > <h4 class="h3 mb-4"> Importance of antibody validation </h4> <div> <p><span class="TextRun Highlight SCXW235494464 BCX0" lang="EN-GB" xml:lang="EN-GB" data-contrast="none"><span class="NormalTextRun SCXW235494464 BCX0" data-ccp-charstyle="normaltextrun" data-ccp-charstyle-defn="{"ObjectId":"22145183-8d30-44f6-a834-da8f52abd0f3|120","ClassId":1073872969,"Properties":[469775450,"normaltextrun",201340122,"1",134233614,"true",469778129,"normaltextrun",335572020,"1",469778324,"Default Paragraph Font"]}">Antibody and assay validation ensures the reliability, accuracy, and reproducibility of multiplexed immunofluorescence results. </span></span><span class="TextRun SCXW235494464 BCX0" lang="EN-GB" xml:lang="EN-GB" data-contrast="auto"><span class="NormalTextRun SCXW235494464 BCX0">The validation of antibodies is of utmost importance as it serves as a foundation for scientific progress in antibody-based assays. Antibody validation is the experimental evidence and documentation demonstrating a specific antibody’s</span><span class="NormalTextRun SCXW235494464 BCX0"> suitability for its intended application or purpose<sup>1</sup>. Consequently, antibodies must </span><span class="NormalTextRun SCXW235494464 BCX0">exhibit</span><span class="NormalTextRun SCXW235494464 BCX0"> specificity, sensitivity, and reproducibility. They should detect only the antigens of interest, even at low expression levels, while consistently performing across different batches of the same antibody clone. At Lunaphore, by </span><span class="NormalTextRun SCXW235494464 BCX0">establishing</span><span class="NormalTextRun SCXW235494464 BCX0"> standardized protocols, sharing validated reagents and reference samples, and conducting inter-</span><span class="NormalTextRun SCXW235494464 BCX0">laboratory comparisons, we can improve the reproducibility of assays and </span><span class="NormalTextRun SCXW235494464 BCX0">facilitate</span><span class="NormalTextRun SCXW235494464 BCX0"> result comparisons across </span><span class="NormalTextRun SCXW235494464 BCX0">various studies</span><span class="NormalTextRun SCXW235494464 BCX0">.</span></span><span class="EOP SCXW235494464 BCX0" data-ccp-props="{"201341983":0,"335559739":200,"335559740":276}"> </span></p> </div> </div> </div> </div> </section>  <section class="section-subheader" > <div class="container"> <div class="row justify-content-lg-between justify-content-center"> <div class="col-lg-5"> <h4 class="h3 mb-4"> Our antibody validation process </h4> </div> <div class="col-lg-6"> <div class="row mb-5"> <div class="col-lg-12 d-flex align-items-start "> <img class="mr-3" width="65" src="https://lunaphore.com/wp-content/uploads/2023/10/icon-1.png" alt=""> <div class="mb-4"> <h6 class="pt-1"> Antibody scouting </h6> <p><span class="TextRun Highlight SCXW238689613 BCX0" lang="EN-GB" xml:lang="EN-GB" data-contrast="none"><span class="NormalTextRun SCXW238689613 BCX0" data-ccp-charstyle="normaltextrun" data-ccp-charstyle-defn="{"ObjectId":"22145183-8d30-44f6-a834-da8f52abd0f3|120","ClassId":1073872969,"Properties":[469775450,"normaltextrun",201340122,"1",134233614,"true",469778129,"normaltextrun",335572020,"1",469778324,"Default Paragraph Font"]}">S</span><span class="NormalTextRun SCXW238689613 BCX0" data-ccp-charstyle="normaltextrun">elect</span><span class="NormalTextRun SCXW238689613 BCX0" data-ccp-charstyle="normaltextrun">ing</span><span class="NormalTextRun SCXW238689613 BCX0" data-ccp-charstyle="normaltextrun"> an antibody clone that was previously well-referenced in the literature or tested in-house to assess its suitability for the </span></span><a class="Hyperlink SCXW238689613 BCX0" href="https://lunaphore.com/our-technology/" target="_blank" rel="noreferrer noopener"><span class="TextRun Highlight Underlined SCXW238689613 BCX0" lang="EN-GB" xml:lang="EN-GB" data-contrast="none"><span class="NormalTextRun SCXW238689613 BCX0" data-ccp-charstyle="Hyperlink">sequential immunofluorescence (</span><span class="NormalTextRun SCXW238689613 BCX0" data-ccp-charstyle="Hyperlink">seqIF™</span><span class="NormalTextRun SCXW238689613 BCX0" data-ccp-charstyle="Hyperlink">)</span></span></a><span class="TextRun Highlight SCXW238689613 BCX0" lang="EN-GB" xml:lang="EN-GB" data-contrast="none"> <span class="NormalTextRun SCXW238689613 BCX0" data-ccp-charstyle="normaltextrun">application on </span></span><a class="Hyperlink SCXW238689613 BCX0" href="https://lunaphore.com/products/comet/" target="_blank" rel="noreferrer noopener"><span class="TextRun Highlight Underlined SCXW238689613 BCX0" lang="EN-GB" xml:lang="EN-GB" data-contrast="none"><span class="NormalTextRun SCXW238689613 BCX0" data-ccp-charstyle="Hyperlink">COMET™</span></span></a><span class="TextRun Highlight SCXW238689613 BCX0" lang="EN-GB" xml:lang="EN-GB" data-contrast="none"><span class="NormalTextRun SCXW238689613 BCX0" data-ccp-charstyle="normaltextrun">.</span></span><span class="EOP SCXW238689613 BCX0" data-ccp-props="{"201341983":0,"335559739":200,"335559740":276}"> </span></p> </div> </div> <div class="col-lg-12 d-flex align-items-start "> <img class="mr-3" width="65" src="https://lunaphore.com/wp-content/uploads/2023/10/icon-2.png" alt=""> <div class="mb-4"> <h6 class="pt-1"> Specificity verification </h6> <p><span class="TextRun SCXW75613333 BCX0" lang="EN-GB" xml:lang="EN-GB" data-contrast="auto"><span class="NormalTextRun SCXW75613333 BCX0">Compar</span><span class="NormalTextRun SCXW75613333 BCX0">ing</span><span class="NormalTextRun SCXW75613333 BCX0"> staining performance of primary antibody candidates on COMET™ with positive organ. Assessing specific staining patterns by comparing positive and negative tissue.</span></span><span class="EOP SCXW75613333 BCX0" data-ccp-props="{"201341983":0,"335559739":200,"335559740":276}"> </span></p> </div> </div> <div class="col-lg-12 d-flex align-items-start "> <img class="mr-3" width="65" src="https://lunaphore.com/wp-content/uploads/2023/10/icon-3.png" alt=""> <div class="mb-4"> <h6 class="pt-1"> Sensitivity verification </h6> <p><span class="TextRun SCXW216957269 BCX0" lang="EN-GB" xml:lang="EN-GB" data-contrast="auto"><span class="NormalTextRun SCXW216957269 BCX0">Testing antibody on heterogenous tissue and confirming dynamic range across different cells and tissue regions.</span></span><span class="EOP SCXW216957269 BCX0" data-ccp-props="{"201341983":0,"335559739":200,"335559740":276}"> </span></p> </div> </div> <div class="col-lg-12 d-flex align-items-start "> <img class="mr-3" width="65" src="https://lunaphore.com/wp-content/uploads/2023/10/icon-4.png" alt=""> <div class="mb-4"> <h6 class="pt-1"> Cross-validation seqIF™-IHC </h6> <p><span class="TextRun SCXW193004361 BCX0" lang="EN-GB" xml:lang="EN-GB" data-contrast="auto"><span class="NormalTextRun SCXW193004361 BCX0">Performing </span><span class="NormalTextRun SpellingErrorV2Themed SCXW193004361 BCX0">seqIF</span><span class="NormalTextRun SCXW193004361 BCX0">™ with the selected antibody and IHC with the pathology-routine antibody on the same slide. Comparing staining pattern and intensity.</span></span><span class="EOP SCXW193004361 BCX0" data-ccp-props="{"201341983":0,"335559739":200,"335559740":276}"> </span></p> </div> </div> </div> </div> </div> </div> </section>  <section class="section-subheader" id='8029027679'> <div class="container"> <h2 class="h1 mb-5">Products</h2> <div class="row"> <div class="col-lg-4 mb-3"> <div class="banner-product"> <div> <h4>Primary antibodies</h4> <p class="display-text"></p> </div> <img src="https://lunaphore.com/wp-content/uploads/2024/07/6tubes_2-transparent-backgroung.png" alt="Primary antibodies's product front view"> <div class="section-buttons-hover"> <p class="display-text"> </p> <div class="buttons-box"> <a href="https://lunaphore.com/spyre-antibody-panels/" class="btn btn-xs btn-primary" aria-label="Learn more about Primary antibodies" target="" > Learn more </a> </div> </div> </div> </div> <div class="col-lg-4 mb-3"> <div class="banner-product"> <div> <h4>Detection reagents</h4> <p class="display-text"></p> </div> <img src="https://lunaphore.com/wp-content/uploads/2023/03/SecAb-renders.png" alt="Detection reagents's product front view"> <div class="section-buttons-hover"> <p class="display-text"> </p> <div class="buttons-box"> <a href="https://lunaphore.com/secondary-antibodies/" class="btn btn-xs btn-primary" aria-label="Learn more about Detection reagents" target="" > Learn more </a> </div> </div> </div> </div> <div class="col-lg-4 mb-3"> <div class="banner-product"> <div> <h4>SPYRE™ Signal Amplification Kit</h4> <p class="display-text"></p> </div> <img src="https://lunaphore.com/wp-content/uploads/2024/10/sigAmpRender-1.png" alt="SPYRE™ Signal Amplification Kit's product front view"> <div class="section-buttons-hover"> <p class="display-text"> </p> <div class="buttons-box"> <a href="https://lunaphore.com/spyre-signal-amplification-kit/" class="btn btn-xs btn-primary" aria-label="Learn more about SPYRE™ Signal Amplification Kit" target="" > Learn more </a> </div> </div> </div> </div> </div> </section>  <section class="section-default" id='wysiwyg-1732380745'> <div class="container my-5"> <div class="row justify-content-center"> <div class="col-11 col-md-10 col-lg-8"> <div class="mt-4"> <div class="wysiwyg-box"> <p><em><span style="font-size: 8pt;"><sup>1</sup> Weller MG. Ten Basic Rules of Antibody Validation. Anal Chem Insights. 2018; 13. doi: 10.1177/1177390118757462.</span></em></p> </div> </div> </div> </div> </div> </section> <section class="section-subheader" > <div class="container"> <div class="carousel-banners"> <div class="banner banner-big"> <div class="row justify-content-between"> <div class="col-md-5 pr-md-0"> <div class="banner-image image-cover" style="background-image:url('https://lunaphore.com/wp-content/uploads/2023/10/NL_Banner-Large-38.png')"></div> </div> <div class="col-md-7 col-lg-6"> <div class="banner-content"> <div> <h5 class="banner-title h4 mb-5"> Explore robust antibody and panel validation for unmatched research reliability. </h5> </div> <div> <a class="btn-link link-arrow" href="https://lunaphore.com/resource-center/white-paper/antibody-and-panel-validation-to-advance-spatial-biology-research/" aria-label="Download the White Paper Explore robust antibody and panel validation for unmatched research reliability."> <span>Download the White Paper</span> </a> </div> </div> </div> </div> </div> </div> </div> </section> <footer class="main-footer mt-5"> <div class="container-fluid mw-1600"> <div class="row justify-content-between"> <div class="col-lg-3 mb-4 text-center text-lg-left pr-lg-4"> <img width="40" class="mb-4" src="https://lunaphore.com/wp-content/themes/mokatheme/assets/img/lunaphore.svg" alt="Lunaphore's logo"> <p>COMET™ is CE/UKCA/UL marked and is For Research Use Only. 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