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Timidilat sintaza — Википедија

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href=\"/wiki/%D0%92%D0%B8%D0%BA%D0%B8%D0%BF%D0%B5%D0%B4%D0%B8%D1%98%D0%B0:%D0%A2%D0%B0%D0%BA%D0%BC%D0%B8%D1%87%D0%B5%D1%9A%D0%B5_%D1%83_%D0%BF%D0%B8%D1%81%D0%B0%D1%9A%D1%83_%D1%87%D0%BB%D0%B0%D0%BD%D0%B0%D0%BA%D0%B0/%D0%A3_%D1%81%D0%B2%D0%B5%D1%82%D1%83_%D0%A4%D0%BB%D0%BE%D1%80%D0%B5_%D0%B8_%D0%A4%D0%B0%D1%83%D0%BD%D0%B5\" title=\"Википедија:Такмичење у писању чланака/У свету Флоре и Фауне\"\u003EФлоре и фауне\u003C/a\u003E\u003C/b\u003E.\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\n\u003Cdiv class=\"noticebanner\"\u003E\u003Cdiv class=\"plainlinks\" style=\"background-color: #FBEBEA; border-radius:5px; margin-top:10px; position:relative; border: 1px solid #aaa; font-family: \u0026#39;Helvetica\u0026#39;, \u0026#39;Arial\u0026#39;, sans-serif; line-height: 18px; box-shadow: 0 1px 1px rgba( 0, 0, 0, 0.15 ); overflow:hidden;\"\u003E\u003Cdiv style=\"display:block; top:4px; width:100%; text-align:center;;\"\u003E\u003Cdiv style=\"color:#000085; font-size:25px; line-height:25px\"\u003E\u003Cdiv style=\"padding-left:50px;\"\u003E\u003C/div\u003E\u003C/div\u003E\u003Cdiv style=\"padding-top:2px; color:#444; font-size:1.15em; line-height:1.5;\"\u003E\u003Cdiv style=\"padding-left:8px; padding-right:8px;\"\u003EПридружите се \u003Cb\u003E\u003Ca href=\"/wiki/%D0%92%D0%B8%D0%BA%D0%B8%D0%BF%D0%B5%D0%B4%D0%B8%D1%98%D0%B0:%D0%A3%D1%80%D0%B5%D1%92%D0%B8%D0%B2%D0%B0%D1%87%D0%BA%D0%B8_%D0%BC%D0%B0%D1%80%D0%B0%D1%82%D0%BE%D0%BD_%D0%92%D0%B8%D0%BA%D0%B8_%D0%B2%D0%BE%D0%BB%D0%B8_%D1%98%D0%B0%D0%B2%D0%BD%D1%83_%D1%83%D0%BC%D0%B5%D1%82%D0%BD%D0%BE%D1%81%D1%82_%D0%B8_%D0%B3%D1%80%D0%BE%D0%B1%D0%BD%D0%B0_%D0%BE%D0%B1%D0%B5%D0%BB%D0%B5%D0%B6%D1%98%D0%B0_2024.\" title=\"Википедија:Уређивачки маратон Вики воли јавну уметност и гробна обележја 2024.\"\u003EУређивачком маратону Вики воли јавну уметност и гробна обележја 2024\u003C/a\u003E\u003C/b\u003E.\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\n\u003Cdiv 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значајних жена\u003C/a\u003E\u003C/b\u003E на Викицитату.\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\n\u003Cdiv class=\"noticebanner\"\u003E\u003Cdiv class=\"plainlinks\" style=\"background-color: #FBEBEA; border-radius:5px; margin-top:10px; position:relative; border: 1px solid #aaa; font-family: \u0026#39;Helvetica\u0026#39;, \u0026#39;Arial\u0026#39;, sans-serif; line-height: 18px; box-shadow: 0 1px 1px rgba( 0, 0, 0, 0.15 ); overflow:hidden;\"\u003E\u003Cdiv style=\"display:block; top:4px; width:100%; text-align:center;;\"\u003E\u003Cdiv style=\"color:#000085; font-size:25px; line-height:25px\"\u003E\u003Cdiv style=\"padding-left:50px;\"\u003E\u003C/div\u003E\u003C/div\u003E\u003Cdiv style=\"padding-top:2px; color:#444; font-size:1.15em; line-height:1.5;\"\u003E\u003Cdiv style=\"padding-left:8px; padding-right:8px;\"\u003EПридружите се \u003Cb\u003E\u003Ca href=\"/wiki/%D0%92%D0%B8%D0%BA%D0%B8%D0%BF%D0%B5%D0%B4%D0%B8%D1%98%D0%B0:%D0%90%D0%BA%D1%86%D0%B8%D1%98%D0%B0_%D0%BF%D1%80%D0%BE%D1%88%D0%B8%D1%80%D0%B8%D0%B2%D0%B0%D1%9A%D0%B0_%D0%BA%D0%BB%D0%B8%D1%86%D0%B0\" title=\"Википедија:Акција проширивања клица\"\u003Eакцији проширивања клица\u003C/a\u003E\u003C/b\u003E.\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E";}}());</script></div> </div> <div class="vector-column-start"> <div class="vector-main-menu-container"> <div id="mw-navigation"> <nav id="mw-panel" class="vector-main-menu-landmark" aria-label="Сајт"> <div id="vector-main-menu-pinned-container" class="vector-pinned-container"> </div> </nav> </div> </div> <div class="vector-sticky-pinned-container"> <nav id="mw-panel-toc" aria-label="Садржај" data-event-name="ui.sidebar-toc" class="mw-table-of-contents-container vector-toc-landmark"> <div id="vector-toc-pinned-container" class="vector-pinned-container"> <div id="vector-toc" class="vector-toc vector-pinnable-element"> <div class="vector-pinnable-header vector-toc-pinnable-header vector-pinnable-header-pinned" data-feature-name="toc-pinned" data-pinnable-element-id="vector-toc" > <h2 class="vector-pinnable-header-label">Садржај</h2> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-toc.pin">помери на страну</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-toc.unpin">сакриј</button> </div> <ul class="vector-toc-contents" id="mw-panel-toc-list"> <li id="toc-mw-content-text" class="vector-toc-list-item vector-toc-level-1"> <a href="#" class="vector-toc-link"> <div class="vector-toc-text">Почетак</div> </a> </li> <li id="toc-Reference" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Reference"> <div class="vector-toc-text"> <span class="vector-toc-numb">1</span> <span>Reference</span> </div> </a> <ul id="toc-Reference-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Literatura" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Literatura"> <div class="vector-toc-text"> <span class="vector-toc-numb">2</span> <span>Literatura</span> </div> </a> <ul id="toc-Literatura-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Spoljašnje_veze" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Spoljašnje_veze"> <div class="vector-toc-text"> <span class="vector-toc-numb">3</span> <span>Spoljašnje veze</span> </div> </a> <ul id="toc-Spoljašnje_veze-sublist" class="vector-toc-list"> </ul> </li> </ul> </div> </div> </nav> </div> </div> <div class="mw-content-container"> <main id="content" class="mw-body"> <header class="mw-body-header vector-page-titlebar"> <nav aria-label="Садржај" class="vector-toc-landmark"> <div id="vector-page-titlebar-toc" class="vector-dropdown vector-page-titlebar-toc vector-button-flush-left" > <input type="checkbox" id="vector-page-titlebar-toc-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-titlebar-toc" class="vector-dropdown-checkbox " aria-label="Прикажи/сакриј садржај" > <label id="vector-page-titlebar-toc-label" for="vector-page-titlebar-toc-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-listBullet mw-ui-icon-wikimedia-listBullet"></span> <span class="vector-dropdown-label-text">Прикажи/сакриј садржај</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-titlebar-toc-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <h1 id="firstHeading" class="firstHeading mw-first-heading"><span class="mw-page-title-main">Timidilat sintaza</span></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" > <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="Чланак на другим језицима. Доступан на: 10" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-10" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">10 језика</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-cy mw-list-item"><a href="https://cy.wikipedia.org/wiki/TYMS" title="TYMS — велшки" lang="cy" hreflang="cy" data-title="TYMS" data-language-autonym="Cymraeg" data-language-local-name="велшки" class="interlanguage-link-target"><span>Cymraeg</span></a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/Thymidylat-Synthase" title="Thymidylat-Synthase — немачки" lang="de" hreflang="de" data-title="Thymidylat-Synthase" data-language-autonym="Deutsch" data-language-local-name="немачки" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-en mw-list-item"><a href="https://en.wikipedia.org/wiki/Thymidylate_synthase" title="Thymidylate synthase — енглески" lang="en" hreflang="en" data-title="Thymidylate synthase" data-language-autonym="English" data-language-local-name="енглески" class="interlanguage-link-target"><span>English</span></a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/Timidilato_sintasa" title="Timidilato sintasa — шпански" lang="es" hreflang="es" data-title="Timidilato sintasa" data-language-autonym="Español" data-language-local-name="шпански" class="interlanguage-link-target"><span>Español</span></a></li><li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/Thymidylate_synthase" title="Thymidylate synthase — француски" lang="fr" hreflang="fr" data-title="Thymidylate synthase" data-language-autonym="Français" data-language-local-name="француски" class="interlanguage-link-target"><span>Français</span></a></li><li class="interlanguage-link interwiki-it mw-list-item"><a href="https://it.wikipedia.org/wiki/Timidilato_sintasi" title="Timidilato sintasi — италијански" lang="it" hreflang="it" data-title="Timidilato sintasi" data-language-autonym="Italiano" data-language-local-name="италијански" class="interlanguage-link-target"><span>Italiano</span></a></li><li class="interlanguage-link interwiki-pl mw-list-item"><a href="https://pl.wikipedia.org/wiki/Syntaza_tymidylanowa" title="Syntaza tymidylanowa — пољски" lang="pl" hreflang="pl" data-title="Syntaza tymidylanowa" data-language-autonym="Polski" data-language-local-name="пољски" class="interlanguage-link-target"><span>Polski</span></a></li><li class="interlanguage-link interwiki-pt mw-list-item"><a href="https://pt.wikipedia.org/wiki/Timidilato_sintetase" title="Timidilato sintetase — португалски" lang="pt" hreflang="pt" data-title="Timidilato sintetase" data-language-autonym="Português" data-language-local-name="португалски" class="interlanguage-link-target"><span>Português</span></a></li><li class="interlanguage-link interwiki-sh mw-list-item"><a href="https://sh.wikipedia.org/wiki/Timidilatna_sintaza" title="Timidilatna sintaza — српскохрватски" lang="sh" hreflang="sh" data-title="Timidilatna sintaza" data-language-autonym="Srpskohrvatski / српскохрватски" data-language-local-name="српскохрватски" class="interlanguage-link-target"><span>Srpskohrvatski / српскохрватски</span></a></li><li class="interlanguage-link interwiki-uk mw-list-item"><a href="https://uk.wikipedia.org/wiki/TYMS" title="TYMS — украјински" lang="uk" hreflang="uk" data-title="TYMS" data-language-autonym="Українська" data-language-local-name="украјински" 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dir="ltr"><style data-mw-deduplicate="TemplateStyles:r28440203">.mw-parser-output .infobox-subbox{padding:0;border:none;margin:-3px;width:auto;min-width:100%;font-size:100%;clear:none;float:none;background-color:transparent}.mw-parser-output .infobox-3cols-child{margin:auto}.mw-parser-output .infobox .navbar{font-size:100%}body.skin-minerva .mw-parser-output .infobox-header,body.skin-minerva .mw-parser-output .infobox-subheader,body.skin-minerva .mw-parser-output .infobox-above,body.skin-minerva .mw-parser-output .infobox-title,body.skin-minerva .mw-parser-output .infobox-image,body.skin-minerva .mw-parser-output .infobox-full-data,body.skin-minerva .mw-parser-output .infobox-below{text-align:center}@media screen{html.skin-theme-clientpref-night .mw-parser-output .infobox-full-data:not(.notheme)>div:not(.notheme)[style]{background:#1f1f23!important;color:#f8f9fa}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .infobox-full-data:not(.notheme) div:not(.notheme){background:#1f1f23!important;color:#f8f9fa}}@media(min-width:640px){body.skin--responsive .mw-parser-output .infobox-table{display:table!important}body.skin--responsive .mw-parser-output .infobox-table>caption{display:table-caption!important}body.skin--responsive .mw-parser-output .infobox-table>tbody{display:table-row-group}body.skin--responsive .mw-parser-output .infobox-table tr{display:table-row!important}body.skin--responsive .mw-parser-output .infobox-table th,body.skin--responsive .mw-parser-output .infobox-table td{padding-left:inherit;padding-right:inherit}}</style><table class="infobox"><tbody><tr><th colspan="2" class="infobox-above">Timidilat sintaza</th></tr><tr><td colspan="2" class="infobox-image"><span typeof="mw:File"><a href="/wiki/%D0%94%D0%B0%D1%82%D0%BE%D1%82%D0%B5%D0%BA%D0%B0:5x5d.jpg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/5/58/5x5d.jpg/270px-5x5d.jpg" decoding="async" width="270" height="215" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/5/58/5x5d.jpg/405px-5x5d.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/5/58/5x5d.jpg/540px-5x5d.jpg 2x" data-file-width="1000" data-file-height="797" /></a></span><div class="infobox-caption">Timidilat sintaza dimer, Human</div></td></tr><tr><th colspan="2" class="infobox-header" style="background-color: #ddd">Identifikatori</th></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3"><a href="/wiki/Klasifikacija_enzima" title="Klasifikacija enzima">EC broj</a></th><td class="infobox-data" style="background-color: #eee"><a rel="nofollow" class="external text" href="http://www.chem.qmul.ac.uk/iubmb/enzyme/EC2/1/1/45.html">2.1.1.45</a></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3"><a href="/wiki/%D0%A6%D0%90%D0%A1_%D1%80%D0%B5%D0%B3%D0%B8%D1%81%D1%82%D0%B0%D1%80%D1%81%D0%BA%D0%B8_%D0%B1%D1%80%D0%BE%D1%98" title="ЦАС регистарски број">CAS broj</a></th><td class="infobox-data" style="background-color: #eee"><a rel="nofollow" class="external text" href="https://commonchemistry.cas.org/detail?cas_rn=9031-61-2&amp;title=">9031-61-2 </a></td></tr><tr><th colspan="2" class="infobox-header" style="background-color: #ddd">Baze podataka</th></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3"><a href="/wiki/IntEnz" title="IntEnz">IntEnz</a></th><td class="infobox-data" style="background-color: #eee"><a rel="nofollow" class="external text" href="http://www.ebi.ac.uk/intenz/query?cmd=SearchEC&amp;ec=2.1.1.45">IntEnz pregled</a></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3"><a href="/wiki/BRENDA" title="BRENDA">BRENDA</a></th><td class="infobox-data" style="background-color: #eee"><a rel="nofollow" class="external text" href="http://www.brenda-enzymes.org/enzyme.php?ecno=2.1.1.45">BRENDA pristup</a></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3"><a href="/wiki/ExPASy" title="ExPASy">ExPASy</a></th><td class="infobox-data" style="background-color: #eee"><a rel="nofollow" class="external text" href="http://www.expasy.org/enzyme/2.1.1.45">NiceZyme pregled</a></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3"><a href="/wiki/KEGG" title="KEGG">KEGG</a></th><td class="infobox-data" style="background-color: #eee"><a rel="nofollow" class="external text" href="http://www.genome.ad.jp/dbget-bin/www_bget?enzyme+2.1.1.45">KEGG pristup</a></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3"><a href="/wiki/MetaCyc" title="MetaCyc">MetaCyc</a></th><td class="infobox-data" style="background-color: #eee"><a rel="nofollow" class="external text" href="http://biocyc.org/META/substring-search?type=NIL&amp;object=2.1.1.45">metabolički put</a></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3"><a href="/wiki/PRIAM_enzim_specifi%C4%8Dni_profili" title="PRIAM enzim specifični profili">PRIAM</a></th><td class="infobox-data" style="background-color: #eee"><a rel="nofollow" class="external text" href="http://priam.prabi.fr/cgi-bin/PRIAM_profiles_CurrentRelease.pl?EC=2.1.1.45">profil</a></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3">Strukture <a href="/wiki/Proteinska_banka_podataka" title="Proteinska banka podataka">PBP</a></th><td class="infobox-data" style="background-color: #eee"><small><a rel="nofollow" class="external text" href="https://www.rcsb.org/search?q=rcsb_polymer_entity.rcsb_ec_lineage.id:2.1.1.45">RCSB PDB</a> <a rel="nofollow" class="external text" href="https://www.ebi.ac.uk/pdbe/entry/search/index?ec_number:2.1.1.45">PDBe</a> <a rel="nofollow" class="external text" href="https://pdbj.org/mine/sql?query=SELECT+DISTINCT+pdbid+FROM+entity+WHERE+entity.pdbx_ec%3D%272.1.1.45%27">PDBj</a> <a rel="nofollow" class="external text" href="https://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/enzymes/GetPage.pl?ec_number=2.1.1.45">PDBsum</a></small></td></tr><tr><td colspan="2" class="infobox-full-data" style="background-color: #eee"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r28440203"><table class="infobox collapsible collapsed" style="float:none; clear:none; margin:0; border-width:0; border-collapse:collapse; text-align:left; width:100%"><tbody><tr><th colspan="2" class="infobox-header" style="background-color: #ddd">Pretraga</th></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3; border:#fafafa 2px solid; border-width:3px 2px 0 0;"><a href="/wiki/PubMed_Central" title="PubMed Central">PMC</a></th><td class="infobox-data" style="background-color: #eee; border:#fafafa 2px solid; border-width:3px 0 0 2px;"><a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&amp;term=2.1.1.45%5BEC/RN%20Number%5D%20AND%20pubmed%20pmc%20local%5Bsb%5D">članci</a></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3; border:#fafafa 2px solid; border-width:3px 2px 0 0;"><a href="/wiki/PubMed" title="PubMed">PubMed</a></th><td class="infobox-data" style="background-color: #eee; border:#fafafa 2px solid; border-width:3px 0 0 2px;"><a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&amp;term=2.1.1.45%5BEC/RN%20Number%5D">članci</a></td></tr><tr><th scope="row" class="infobox-label" style="background-color: #e7dcc3; border:#fafafa 2px solid; border-width:3px 2px 0 0;"><a href="/wiki/Nacionalni_centar_za_biotehnolo%C5%A1ke_informacije" title="Nacionalni centar za biotehnološke informacije">NCBI</a></th><td class="infobox-data" style="background-color: #eee; border:#fafafa 2px solid; border-width:3px 0 0 2px;"><a rel="nofollow" class="external text" href="http://www.ncbi.nlm.nih.gov/protein?term=2.1.1.45%5BEC/RN%20Number%5D">proteini</a></td></tr></tbody></table></td></tr></tbody></table> <p><b>Timidilat sintaza</b> (<a href="/wiki/Klasifikacija_enzima" title="Klasifikacija enzima">EC</a> <a rel="nofollow" class="external text" href="http://enzyme.expasy.org/EC/2.1.1.45">2.1.1.45</a>, <i>dTMP sintaza</i>, <i>timidilatna sintetaza</i>, <i>metilintetrahidrofolat:dUMP C-metiltransferaza</i>, <i>TMP sintetaza</i>) je <a href="/wiki/%D0%95%D0%BD%D0%B7%D0%B8%D0%BC" title="Ензим">enzim</a> sa sistematskim imenom <i>5,10-metilintetrahidrofolat:dUMP C-metiltransferaza</i>.<sup id="cite_ref-1" class="reference"><a href="#cite_note-1"><span class="cite-bracket">&#91;</span>1<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-2" class="reference"><a href="#cite_note-2"><span class="cite-bracket">&#91;</span>2<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-3" class="reference"><a href="#cite_note-3"><span class="cite-bracket">&#91;</span>3<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-4" class="reference"><a href="#cite_note-4"><span class="cite-bracket">&#91;</span>4<span class="cite-bracket">&#93;</span></a></sup> Ovaj enzim <a href="/wiki/%D0%9A%D0%B0%D1%82%D0%B0%D0%BB%D0%B8%D0%B7%D0%B0" title="Катализа">katalizuje</a> sledeću <a href="/wiki/%D0%A5%D0%B5%D0%BC%D0%B8%D1%98%D1%81%D0%BA%D0%B0_%D1%80%D0%B5%D0%B0%D0%BA%D1%86%D0%B8%D1%98%D0%B0" title="Хемијска реакција">hemijsku reakciju</a> </p> <dl><dd>5,10-metilintetrahidrofolat + dUMP <span class="mwe-math-element"><span class="mwe-math-mathml-inline mwe-math-mathml-a11y" style="display: none;"><math xmlns="http://www.w3.org/1998/Math/MathML" alttext="{\displaystyle \rightleftharpoons }"> <semantics> <mrow class="MJX-TeXAtom-ORD"> <mstyle displaystyle="true" scriptlevel="0"> <mo class="MJX-variant" stretchy="false">&#x21CC;<!-- ⇌ --></mo> </mstyle> </mrow> <annotation encoding="application/x-tex">{\displaystyle \rightleftharpoons }</annotation> </semantics> </math></span><img src="https://wikimedia.org/api/rest_v1/media/math/render/svg/1c37b981df851b9e54e489e017b1481e37d418f3" class="mwe-math-fallback-image-inline mw-invert skin-invert" aria-hidden="true" style="vertical-align: -0.338ex; width:2.324ex; height:1.843ex;" alt="{\displaystyle \rightleftharpoons }"></span> dihidrofolat + dTMP</dd></dl> <div class="mw-heading mw-heading2"><h2 id="Reference">Reference</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Timidilat_sintaza&amp;veaction=edit&amp;section=1" title="Уредите одељак „Reference”" class="mw-editsection-visualeditor"><span>уреди</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Timidilat_sintaza&amp;action=edit&amp;section=1" title="Уреди извор одељка: Reference"><span>уреди извор</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r28440201">.mw-parser-output .reflist{margin-bottom:0.5em;list-style-type:decimal}@media screen{.mw-parser-output .reflist{font-size:90%}}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output .reflist-columns-2{column-width:30em}.mw-parser-output .reflist-columns-3{column-width:25em}.mw-parser-output .reflist-columns{margin-top:0.3em}.mw-parser-output .reflist-columns ol{margin-top:0}.mw-parser-output .reflist-columns li{page-break-inside:avoid;break-inside:avoid-column}.mw-parser-output .reflist-upper-alpha{list-style-type:upper-alpha}.mw-parser-output .reflist-upper-roman{list-style-type:upper-roman}.mw-parser-output .reflist-lower-alpha{list-style-type:lower-alpha}.mw-parser-output .reflist-lower-greek{list-style-type:lower-greek}.mw-parser-output .reflist-lower-roman{list-style-type:lower-roman}</style><div class="reflist"> <div class="mw-references-wrap"><ol class="references"> <li id="cite_note-1"><span class="mw-cite-backlink"><b><a href="#cite_ref-1">^</a></b></span> <span class="reference-text"><cite class="citation journal">Blakley, R.L. (1963). <a rel="nofollow" class="external text" href="https://archive.org/details/sim_journal-of-biological-chemistry_1963-06_238_6/page/2113">„The biosynthesis of thymidylic acid. IV. Further studies on thymidylate synthase”</a>. <i>J. Biol. Chem</i>. <b>238</b>: 2113—2118.</cite><span title="ctx_ver=Z39.88-2004&amp;rfr_id=info%3Asid%2Fsr.wikipedia.org%3ATimidilat+sintaza&amp;rft.atitle=The+biosynthesis+of+thymidylic+acid.+IV.+Further+studies+on+thymidylate+synthase&amp;rft.au=Blakley%2C+R.L.&amp;rft.date=1963&amp;rft.genre=article&amp;rft.jtitle=J.+Biol.+Chem.&amp;rft.pages=2113-2118&amp;rft.volume=238&amp;rft_id=https%3A%2F%2Farchive.org%2Fdetails%2Fsim_journal-of-biological-chemistry_1963-06_238_6%2Fpage%2F2113&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;">&#160;</span></span></span> </li> <li id="cite_note-2"><span class="mw-cite-backlink"><b><a href="#cite_ref-2">^</a></b></span> <span class="reference-text"><cite class="citation journal">Lockshin, A., Moran, R.G. and Danenberg, P.V. (1979). „Thymidylate synthetase purified to homogeneity from human leukemic cells”. <i>Proc. Natl. Acad. Sci. USA</i>. <b>76</b>: 750—754. <a href="/wiki/PMID" title="PMID">PMID</a>&#160;<a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/34155">34155</a>.</cite><span title="ctx_ver=Z39.88-2004&amp;rfr_id=info%3Asid%2Fsr.wikipedia.org%3ATimidilat+sintaza&amp;rft.atitle=Thymidylate+synthetase+purified+to+homogeneity+from+human+leukemic+cells&amp;rft.au=Lockshin%2C+A.%2C+Moran%2C+R.G.+and+Danenberg%2C+P.V.&amp;rft.date=1979&amp;rft.genre=article&amp;rft.jtitle=Proc.+Natl.+Acad.+Sci.+USA&amp;rft.pages=750-754&amp;rft.volume=76&amp;rft_id=info%3Apmid%2F34155&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;">&#160;</span></span><span class="citation-comment" style="display:none; color:#33aa33; margin-left:0.3em">CS1 одржавање: Вишеструка имена: списак аутора (<a href="/wiki/%D0%9A%D0%B0%D1%82%D0%B5%D0%B3%D0%BE%D1%80%D0%B8%D1%98%D0%B0:CS1_%D0%BE%D0%B4%D1%80%D0%B6%D0%B0%D0%B2%D0%B0%D1%9A%D0%B5:_%D0%92%D0%B8%D1%88%D0%B5%D1%81%D1%82%D1%80%D1%83%D0%BA%D0%B0_%D0%B8%D0%BC%D0%B5%D0%BD%D0%B0:_%D1%81%D0%BF%D0%B8%D1%81%D0%B0%D0%BA_%D0%B0%D1%83%D1%82%D0%BE%D1%80%D0%B0" title="Категорија:CS1 одржавање: Вишеструка имена: списак аутора">веза</a>)</span></span> </li> <li id="cite_note-3"><span class="mw-cite-backlink"><b><a href="#cite_ref-3">^</a></b></span> <span class="reference-text"><cite class="citation journal">Slavik, K. &amp; Slavikova, V. (1980). „Purification of thymidylate synthetase from enzyme-poor sources by affinity chromatography”. <i>Methods Enzymol</i>. <b>66</b>: 709—723. <a href="/wiki/PMID" title="PMID">PMID</a>&#160;<a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/6990200">6990200</a>.</cite><span title="ctx_ver=Z39.88-2004&amp;rfr_id=info%3Asid%2Fsr.wikipedia.org%3ATimidilat+sintaza&amp;rft.atitle=Purification+of+thymidylate+synthetase+from+enzyme-poor+sources+by+affinity+chromatography&amp;rft.au=Slavik%2C+K.&amp;rft.au=Slavikova%2C+V.&amp;rft.date=1980&amp;rft.genre=article&amp;rft.jtitle=Methods+Enzymol.&amp;rft.pages=709-723&amp;rft.volume=66&amp;rft_id=info%3Apmid%2F6990200&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;">&#160;</span></span></span> </li> <li id="cite_note-4"><span class="mw-cite-backlink"><b><a href="#cite_ref-4">^</a></b></span> <span class="reference-text"><cite class="citation journal">Wahba, A.J. &amp; Friedkin, M. (1962). <a rel="nofollow" class="external text" href="https://archive.org/details/sim_journal-of-biological-chemistry_1962-12_237_6/page/3794">„The enzymatic synthesis of thymidylate. I. Early steps in the purification of thymidylate synthetase of <i>Escherichia coli</i>”</a>. <i>J. Biol. Chem</i>. <b>237</b>: 3794—3801. <a href="/wiki/PMID" title="PMID">PMID</a>&#160;<a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/13998281">13998281</a>.</cite><span title="ctx_ver=Z39.88-2004&amp;rfr_id=info%3Asid%2Fsr.wikipedia.org%3ATimidilat+sintaza&amp;rft.atitle=The+enzymatic+synthesis+of+thymidylate.+I.+Early+steps+in+the+purification+of+thymidylate+synthetase+of+Escherichia+coli&amp;rft.au=Friedkin%2C+M.&amp;rft.au=Wahba%2C+A.J.&amp;rft.date=1962&amp;rft.genre=article&amp;rft.jtitle=J.+Biol.+Chem.&amp;rft.pages=3794-3801&amp;rft.volume=237&amp;rft_id=https%3A%2F%2Farchive.org%2Fdetails%2Fsim_journal-of-biological-chemistry_1962-12_237_6%2Fpage%2F3794&amp;rft_id=info%3Apmid%2F13998281&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;">&#160;</span></span></span> </li> </ol></div></div> <div class="mw-heading mw-heading2"><h2 id="Literatura">Literatura</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Timidilat_sintaza&amp;veaction=edit&amp;section=2" title="Уредите одељак „Literatura”" class="mw-editsection-visualeditor"><span>уреди</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Timidilat_sintaza&amp;action=edit&amp;section=2" title="Уреди извор одељка: Literatura"><span>уреди извор</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r28440192">.mw-parser-output .refbegin{margin-bottom:0.5em}.mw-parser-output .refbegin-hanging-indents>ul{margin-left:0}.mw-parser-output .refbegin-hanging-indents>ul>li{margin-left:0;padding-left:3.2em;text-indent:-3.2em}.mw-parser-output .refbegin-hanging-indents ul,.mw-parser-output .refbegin-hanging-indents ul li{list-style:none}@media(max-width:720px){.mw-parser-output .refbegin-hanging-indents>ul>li{padding-left:1.6em;text-indent:-1.6em}}.mw-parser-output .refbegin-columns{margin-top:0.3em}.mw-parser-output .refbegin-columns ul{margin-top:0}.mw-parser-output .refbegin-columns li{page-break-inside:avoid;break-inside:avoid-column}@media screen{.mw-parser-output .refbegin{font-size:90%}}</style><div class="refbegin" style=""> <ul><li><cite class="citation book">Nicholas C. Price; Lewis Stevens (1999). <a rel="nofollow" class="external text" href="http://books.google.com/books/about/Fundamentals_of_enzymology.html?id=8uvwAAAAMAAJ"><i>Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins</i></a> (Third изд.). USA: Oxford University Press. <a href="/wiki/Me%C4%91unarodni_standardni_broj_knjige" title="Međunarodni standardni broj knjige">ISBN</a>&#160;<a href="/wiki/%D0%9F%D0%BE%D1%81%D0%B5%D0%B1%D0%BD%D0%BE:%D0%A8%D1%82%D0%B0%D0%BC%D0%BF%D0%B0%D0%BD%D0%B8_%D0%B8%D0%B7%D0%B2%D0%BE%D1%80%D0%B8/019850229X" title="Посебно:Штампани извори/019850229X">019850229X</a>.</cite><span title="ctx_ver=Z39.88-2004&amp;rfr_id=info%3Asid%2Fsr.wikipedia.org%3ATimidilat+sintaza&amp;rft.au=Lewis+Stevens&amp;rft.au=Nicholas+C.+Price&amp;rft.btitle=Fundamentals+of+Enzymology%3A+The+Cell+and+Molecular+Biology+of+Catalytic+Proteins&amp;rft.date=1999&amp;rft.edition=Third&amp;rft.genre=book&amp;rft.isbn=019850229X&amp;rft.place=USA&amp;rft.pub=Oxford+University+Press&amp;rft_id=http%3A%2F%2Fbooks.google.com%2Fbooks%2Fabout%2FFundamentals_of_enzymology.html%3Fid%3D8uvwAAAAMAAJ&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook" class="Z3988"><span style="display:none;">&#160;</span></span></li> <li><cite class="citation book">Eric J. Toone (2006). <a rel="nofollow" class="external text" href="http://books.google.com/books/about/Advances_in_Enzymology_and_Related_Areas.html?id=Pmh8yToeuloC"><i>Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution</i></a> (Volume 75 изд.). Wiley-Interscience. <a href="/wiki/Me%C4%91unarodni_standardni_broj_knjige" title="Međunarodni standardni broj knjige">ISBN</a>&#160;<a href="/wiki/%D0%9F%D0%BE%D1%81%D0%B5%D0%B1%D0%BD%D0%BE:%D0%A8%D1%82%D0%B0%D0%BC%D0%BF%D0%B0%D0%BD%D0%B8_%D0%B8%D0%B7%D0%B2%D0%BE%D1%80%D0%B8/0471205036" title="Посебно:Штампани извори/0471205036">0471205036</a>.</cite><span title="ctx_ver=Z39.88-2004&amp;rfr_id=info%3Asid%2Fsr.wikipedia.org%3ATimidilat+sintaza&amp;rft.au=Eric+J.+Toone&amp;rft.btitle=Advances+in+Enzymology+and+Related+Areas+of+Molecular+Biology%2C+Protein+Evolution&amp;rft.date=2006&amp;rft.edition=Volume+75&amp;rft.genre=book&amp;rft.isbn=0471205036&amp;rft.pub=Wiley-Interscience&amp;rft_id=http%3A%2F%2Fbooks.google.com%2Fbooks%2Fabout%2FAdvances_in_Enzymology_and_Related_Areas.html%3Fid%3DPmh8yToeuloC&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook" class="Z3988"><span style="display:none;">&#160;</span></span></li> <li><cite class="citation book">Branden C; Tooze J. <a rel="nofollow" class="external text" href="http://www.garlandscience.com/textbooks/0815323042.asp?type=reviews"><i>Introduction to Protein Structure</i></a>. New York, NY: Garland Publishing. <a href="/wiki/Me%C4%91unarodni_standardni_broj_knjige" title="Međunarodni standardni broj knjige">ISBN</a>&#160;<a href="/wiki/%D0%9F%D0%BE%D1%81%D0%B5%D0%B1%D0%BD%D0%BE:%D0%A8%D1%82%D0%B0%D0%BC%D0%BF%D0%B0%D0%BD%D0%B8_%D0%B8%D0%B7%D0%B2%D0%BE%D1%80%D0%B8/0-8153-2305-0" title="Посебно:Штампани извори/0-8153-2305-0">0-8153-2305-0</a>.</cite><span title="ctx_ver=Z39.88-2004&amp;rfr_id=info%3Asid%2Fsr.wikipedia.org%3ATimidilat+sintaza&amp;rft.au=Branden+C&amp;rft.au=Tooze+J.&amp;rft.btitle=Introduction+to+Protein+Structure&amp;rft.genre=book&amp;rft.isbn=0-8153-2305-0&amp;rft.place=New+York%2C+NY&amp;rft.pub=Garland+Publishing&amp;rft_id=http%3A%2F%2Fwww.garlandscience.com%2Ftextbooks%2F0815323042.asp%3Ftype%3Dreviews&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook" class="Z3988"><span style="display:none;">&#160;</span></span></li> <li><cite class="citation book">Irwin H. Segel. <a rel="nofollow" class="external text" href="http://books.google.com/books/about/Enzyme_Kinetics.html?id=T60oAAAAYAAJ"><i>Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems</i></a> (Book 44 изд.). Wiley Classics Library. <a href="/wiki/Me%C4%91unarodni_standardni_broj_knjige" title="Međunarodni standardni broj knjige">ISBN</a>&#160;<a href="/wiki/%D0%9F%D0%BE%D1%81%D0%B5%D0%B1%D0%BD%D0%BE:%D0%A8%D1%82%D0%B0%D0%BC%D0%BF%D0%B0%D0%BD%D0%B8_%D0%B8%D0%B7%D0%B2%D0%BE%D1%80%D0%B8/0471303097" title="Посебно:Штампани извори/0471303097">0471303097</a>.</cite><span title="ctx_ver=Z39.88-2004&amp;rfr_id=info%3Asid%2Fsr.wikipedia.org%3ATimidilat+sintaza&amp;rft.au=Irwin+H.+Segel&amp;rft.btitle=Enzyme+Kinetics%3A+Behavior+and+Analysis+of+Rapid+Equilibrium+and+Steady-State+Enzyme+Systems&amp;rft.edition=Book+44&amp;rft.genre=book&amp;rft.isbn=0471303097&amp;rft.pub=Wiley+Classics+Library&amp;rft_id=http%3A%2F%2Fbooks.google.com%2Fbooks%2Fabout%2FEnzyme_Kinetics.html%3Fid%3DT60oAAAAYAAJ&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook" class="Z3988"><span style="display:none;">&#160;</span></span></li> <li><cite class="citation book">William P. Jencks (1987). <a rel="nofollow" class="external text" href="http://books.google.com/books/about/Catalysis_in_Chemistry_and_Enzymology.html?id=LLkSzP-ct0wC"><i>Catalysis in Chemistry and Enzymology</i></a>. Dover Publications. <a href="/wiki/Me%C4%91unarodni_standardni_broj_knjige" title="Međunarodni standardni broj knjige">ISBN</a>&#160;<a href="/wiki/%D0%9F%D0%BE%D1%81%D0%B5%D0%B1%D0%BD%D0%BE:%D0%A8%D1%82%D0%B0%D0%BC%D0%BF%D0%B0%D0%BD%D0%B8_%D0%B8%D0%B7%D0%B2%D0%BE%D1%80%D0%B8/0486654605" title="Посебно:Штампани извори/0486654605">0486654605</a>.</cite><span title="ctx_ver=Z39.88-2004&amp;rfr_id=info%3Asid%2Fsr.wikipedia.org%3ATimidilat+sintaza&amp;rft.au=William+P.+Jencks&amp;rft.btitle=Catalysis+in+Chemistry+and+Enzymology&amp;rft.date=1987&amp;rft.genre=book&amp;rft.isbn=0486654605&amp;rft.pub=Dover+Publications&amp;rft_id=http%3A%2F%2Fbooks.google.com%2Fbooks%2Fabout%2FCatalysis_in_Chemistry_and_Enzymology.html%3Fid%3DLLkSzP-ct0wC&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook" class="Z3988"><span style="display:none;">&#160;</span></span></li></ul> </div> <div class="mw-heading mw-heading2"><h2 id="Spoljašnje_veze"><span id="Spolja.C5.A1nje_veze"></span>Spoljašnje veze</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Timidilat_sintaza&amp;veaction=edit&amp;section=3" title="Уредите одељак „Spoljašnje veze”" class="mw-editsection-visualeditor"><span>уреди</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Timidilat_sintaza&amp;action=edit&amp;section=3" title="Уреди извор одељка: Spoljašnje veze"><span>уреди извор</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a rel="nofollow" class="external text" href="https://meshb.nlm.nih.gov/record/ui?name=Thymidylate%20synthase">Thymidylate+synthase</a> на <i>US National Library of Medicine Medical Subject Headings</i> (<a href="/wiki/MeSH" title="MeSH">MeSH</a>)</li></ul> <div class="navbox-styles"><style data-mw-deduplicate="TemplateStyles:r25469611">.mw-parser-output .hlist dl,.mw-parser-output .hlist ol,.mw-parser-output .hlist ul{margin:0;padding:0}.mw-parser-output .hlist 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2.1)</div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Spisak_EC_brojeva_(EC_2)#EC_2.1.1:_Methyltransferases" title="Spisak EC brojeva (EC 2)">2.1.1</a>: <a href="/wiki/Metiltransferaza" title="Metiltransferaza">Metil-</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%">N-</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Histamin_N-metiltransferaza" title="Histamin N-metiltransferaza">Histamin N-metiltransferaza</a></li> <li><a href="/wiki/Feniletanolamin_N-metiltransferaza" title="Feniletanolamin N-metiltransferaza">Feniletanolamin N-metiltransferaza</a></li> <li><a href="/wiki/Amin_N-metiltransferaza" title="Amin N-metiltransferaza">Amin N-metiltransferaza</a></li> <li><a href="/wiki/Fosfatidiletanolamin_N-metiltransferaza" title="Fosfatidiletanolamin N-metiltransferaza">fosfatidiletanolamin N-metiltransferaza</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">O-</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Acetilserotonin_O-metiltransferaza" title="Acetilserotonin O-metiltransferaza">5-hidroksiindol-O-metiltransferaza</a>/<a href="/wiki/Acetilserotonin_O-metiltransferaza" title="Acetilserotonin O-metiltransferaza">acetilserotonin O-metiltransferaza</a></li> <li><a href="/wiki/Katehol_O-metiltransferaza" title="Katehol O-metiltransferaza">Katehol O-metiltransferaza</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Homocistein" title="Homocistein">Homocistein</a></th><td class="navbox-list-with-group navbox-list navbox-odd" 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href="/wiki/Fosforibozilglicinamid_formiltransferaza" title="Fosforibozilglicinamid formiltransferaza">Fosforibozilglicinamid formiltransferaza</a></li> <li><a href="/wiki/Inozin_monofosfat_sintaza" class="mw-redirect" title="Inozin monofosfat sintaza">Inozin monofosfat sintaza</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Drugi</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Glutamat_formiminotransferaza" title="Glutamat formiminotransferaza">Glutamat formiminotransferaza</a></li> <li><a href="/wiki/Aminometiltransferaza" title="Aminometiltransferaza">Aminometiltransferaza</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Spisak_EC_brojeva_(EC_2)#EC_2.1.3:_Carboxy-_and_Carbamoyltransferases" title="Spisak EC brojeva (EC 2)">2.1.3</a>: <a href="/wiki/%D0%9A%D0%B0%D1%80%D0%B1%D0%BE%D0%BA%D1%81%D0%B8%D0%BB%D0%BD%D0%B0_%D0%BA%D0%B8%D1%81%D0%B5%D0%BB%D0%B8%D0%BD%D0%B0" title="Карбоксилна киселина">Karboksi</a>-<br />i <a href="/wiki/Karbamoil" class="mw-redirect" title="Karbamoil">karbamoil</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%">Karboksi</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Metilmalonil-KoA_karboksitransferaza" title="Metilmalonil-KoA karboksitransferaza">metilmalonil-KoA karboksitransferaza</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Karbamoil</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Aspartat_karbamoiltransferaza" title="Aspartat karbamoiltransferaza">Aspartat karbamoiltransferaza</a></li> <li><a href="/wiki/Ornitin_karbamoiltransferaza" title="Ornitin karbamoiltransferaza">Ornitin karbamoiltransferaza</a></li> <li><a href="/wiki/Oksamat_karbamoiltransferaza" title="Oksamat karbamoiltransferaza">Oksamat karbamoiltransferaza</a></li> <li><a href="/wiki/Putrescin_karbamoiltransferaza" title="Putrescin karbamoiltransferaza">Putrescin karbamoiltransferaza</a></li> <li><a href="/wiki/3-hidroksimetilcefem_karbamoiltransferaza" title="3-hidroksimetilcefem karbamoiltransferaza">3-hidroksimetilcefem karbamoiltransferaza</a></li> <li><a href="/wiki/Lizin_karbamoiltransferaza" title="Lizin karbamoiltransferaza">Lizin karbamoiltransferaza</a></li> <li><a href="/wiki/N-acetilornitin_karbamoiltransferaza" title="N-acetilornitin karbamoiltransferaza">N-acetilornitin karbamoiltransferaza</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Spisak_EC_brojeva_(EC_2)#EC_2.1.4:_Amidinotransferases" title="Spisak EC brojeva (EC 2)">2.1.4</a>: <a href="/wiki/Amidin" title="Amidin">Amidin</a></th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Arginin:glicin_amidinotransferaza" class="mw-redirect" title="Arginin:glicin amidinotransferaza">Arginin:glicin amidinotransferaza</a></li></ul> </div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r25469611"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r24365370"></div><div role="navigation" class="navbox" aria-labelledby="Enzimi" style="padding:3px"><table class="nowraplinks hlist mw-collapsible mw-collapsed navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r25469611"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r24365379"><div class="navbar plainlinks hlist navbar-mini"><ul><li class="nv-прикажи"><a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Enzimi-lat" title="Шаблон:Enzimi-lat"><abbr title="Погледајте шаблон" style=";;background:none transparent;color:inherit;border:none;box-shadow:none;padding:0;">п</abbr></a></li><li class="nv-разговор"><a href="/wiki/%D0%A0%D0%B0%D0%B7%D0%B3%D0%BE%D0%B2%D0%BE%D1%80_%D0%BE_%D1%88%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD%D1%83:Enzimi-lat" title="Разговор о шаблону:Enzimi-lat"><abbr title="Разговарајте о шаблону" style=";;background:none transparent;color:inherit;border:none;box-shadow:none;padding:0;">р</abbr></a></li><li class="nv-уреди"><a href="/wiki/%D0%9F%D0%BE%D1%81%D0%B5%D0%B1%D0%BD%D0%BE:%D0%A3%D1%80%D0%B5%D0%B4%D0%B8_%D1%81%D1%82%D1%80%D0%B0%D0%BD%D0%B8%D1%86%D1%83/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Enzimi-lat" title="Посебно:Уреди страницу/Шаблон:Enzimi-lat"><abbr title="Уредите шаблон" style=";;background:none transparent;color:inherit;border:none;box-shadow:none;padding:0;">у</abbr></a></li></ul></div><div id="Enzimi" style="font-size:114%;margin:0 4em"><a href="/wiki/%D0%95%D0%BD%D0%B7%D0%B8%D0%BC" title="Ензим">Enzimi</a></div></th></tr><tr><th scope="row" class="navbox-group" style="width:1%">Teme</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Aktivno_mesto" title="Aktivno mesto">Aktivno mesto</a></li> <li><a href="/wiki/Alosterna_regulacija" title="Alosterna regulacija">Alosterna regulacija</a></li> <li><a href="/wiki/Mesto_vezivanja" title="Mesto vezivanja">Mesto vezivanja</a></li> <li><a href="/wiki/Kataliti%C4%8Dki_perfektan_enzim" title="Katalitički perfektan enzim">Katalitički perfektan enzim</a></li> <li><a href="/wiki/Kofaktor_(biohemija)" title="Kofaktor (biohemija)">Koenzim</a></li> <li><a href="/wiki/Kofaktor_(biohemija)" title="Kofaktor (biohemija)">Kofaktor</a></li> <li><a href="/wiki/Kooperativnost_(biohemija)" title="Kooperativnost (biohemija)">Kooperativnost</a></li> <li><a href="/wiki/Klasifikacija_enzima" title="Klasifikacija enzima">EC broj</a></li> <li><a href="/wiki/Enzimska_kataliza" title="Enzimska kataliza">Enzimska kataliza</a></li> <li><a href="/wiki/Inhibitor_enzima" title="Inhibitor enzima">Inhibicija enzima</a></li> <li><a href="/wiki/%D0%95%D0%BD%D0%B7%D0%B8%D0%BC%D1%81%D0%BA%D0%B0_%D0%BA%D0%B8%D0%BD%D0%B5%D1%82%D0%B8%D0%BA%D0%B0" title="Ензимска кинетика">Enzimska kinetika</a></li> <li><a href="/wiki/%D0%9B%D0%B0%D1%98%D0%BD%D0%B2%D0%B8%D0%B2%D0%B5%D1%80%E2%80%94%D0%91%D0%B5%D1%80%D0%BA%D0%BE%D0%B2_%D0%B4%D0%B8%D1%98%D0%B0%D0%B3%D1%80%D0%B0%D0%BC" title="Лајнвивер—Берков дијаграм">Lajnviver—Berkov dijagram</a></li> <li><a href="/wiki/%D0%9C%D0%B8%D1%85%D0%B0%D0%B5%D0%BB%D0%B8%D1%81%E2%80%94%D0%9C%D0%B5%D0%BD%D1%82%D0%B5%D0%BD%D0%B8%D0%BD%D0%B0_%D0%BA%D0%B8%D0%BD%D0%B5%D1%82%D0%B8%D0%BA%D0%B0" title="Михаелис—Ментенина кинетика">Mihaelis—Mentenina kinetika</a></li> <li><a href="/wiki/Spisak_enzima" title="Spisak enzima">Spisak enzima</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%">Tipovi</th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><b>EC1 <a href="/wiki/Oksidoreduktaza" title="Oksidoreduktaza">Oksidoreduktaze</a></b> /<a href="/wiki/Spisak_EC_brojeva_(EC_1)" title="Spisak EC brojeva (EC 1)">spisak</a></li> <li><b>EC2 <a href="/wiki/Transferaza" title="Transferaza">Transferaze</a></b> /<a href="/wiki/Spisak_EC_brojeva_(EC_2)" title="Spisak EC brojeva (EC 2)">spisak</a></li> <li><b>EC3 <a href="/wiki/Hidrolaza" title="Hidrolaza">Hidrolaze</a></b> /<a href="/wiki/Spisak_EC_brojeva_(EC_3)" title="Spisak EC brojeva (EC 3)">spisak</a></li> <li><b>EC4 <a href="/wiki/Lijaza" title="Lijaza">Lijaze</a></b> /<a href="/wiki/Spisak_EC_brojeva_(EC_4)" title="Spisak EC brojeva (EC 4)">spisak</a></li> <li><b>EC5 <a href="/wiki/Izomeraza" title="Izomeraza">Izomeraze</a></b> /<a href="/wiki/Spisak_EC_brojeva_(EC_5)" title="Spisak EC brojeva (EC 5)">spisak</a></li> <li><b>EC6 <a href="/wiki/DNK_ligaza" title="DNK ligaza">Ligaze</a></b> /<a href="/wiki/Spisak_EC_brojeva_(EC_6)" title="Spisak EC brojeva (EC 6)">spisak</a></li></ul> </div></td></tr><tr><td class="navbox-abovebelow" colspan="2"><div> <ul><li><i><a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Biohemija_metanavs-lat" title="Шаблон:Biohemija metanavs-lat">B</a> <a href="/wiki/%D0%95%D0%BD%D0%B7%D0%B8%D0%BC" title="Ензим">enzm</a>: <a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Alkoholne_oksidoreduktaze-lat" title="Шаблон:Alkoholne oksidoreduktaze-lat">1.1</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Aldehid/Okso_oksidoreduktaze-lat" title="Шаблон:Aldehid/Okso oksidoreduktaze-lat">2</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:CH-CH_oksidoreduktaze-lat" title="Шаблон:CH-CH oksidoreduktaze-lat">3</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:CH-NH2_oksidoreduktaze-lat" title="Шаблон:CH-NH2 oksidoreduktaze-lat">4</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:CH-NH_oksidoreduktaze-lat" title="Шаблон:CH-NH oksidoreduktaze-lat">5</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:NADH_ili_NADPH_oksidoreduktaze-lat" title="Шаблон:NADH ili NADPH oksidoreduktaze-lat">6</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Azotni_donor_oksidoreduktaze-lat" title="Шаблон:Azotni donor oksidoreduktaze-lat">7</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Sumporne_oksidoreduktaze-lat" title="Шаблон:Sumporne oksidoreduktaze-lat">8</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Difenolna_familija_oksidoreduktaza-lat" title="Шаблон:Difenolna familija oksidoreduktaza-lat">10</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Peroksidaze-lat" title="Шаблон:Peroksidaze-lat">11</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Monooksigenaze-lat" title="Шаблон:Monooksigenaze-lat">13</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Dioksigenaze-lat" title="Шаблон:Dioksigenaze-lat">14</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Druge_oksidoreduktaze-lat" title="Шаблон:Druge oksidoreduktaze-lat">15-18</a>, <a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Jedan_ugljenik_transferaze-lat" class="mw-redirect" title="Шаблон:Jedan ugljenik transferaze-lat">2.1</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Aldehid-keton_transferaze-lat" title="Шаблон:Aldehid-keton transferaze-lat">2</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Aciltransferaze-lat" title="Шаблон:Aciltransferaze-lat">3</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Glikoziltransferaze-lat" title="Шаблон:Glikoziltransferaze-lat">4</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Alkil_i_aril_transferaze-lat" title="Шаблон:Alkil i aril transferaze-lat">5</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Azotne_transferaze-lat" title="Шаблон:Azotne transferaze-lat">6</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Kinaze-lat" title="Шаблон:Kinaze-lat">7</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Sumpor-sadr%C5%BEavaju%C4%87e-grupe_transferaze-lat" class="mw-redirect" title="Шаблон:Sumpor-sadržavajuće-grupe transferaze-lat">8</a>, <a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Tirozinske_kinaze-lat" title="Шаблон:Tirozinske kinaze-lat">2.7.10</a>, <a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Serin/treonin_specifi%C4%8Dne_proteinske_kinaze-lat" class="mw-redirect" title="Шаблон:Serin/treonin specifične proteinske kinaze-lat">2.7.11-12</a>, <a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Esteraze-lat" title="Шаблон:Esteraze-lat">3.1</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:%C5%A0e%C4%87erne_hidrolaze-lat" title="Шаблон:Šećerne hidrolaze-lat">2</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Etarska_veza_hidrolaze-lat" title="Шаблон:Etarska veza hidrolaze-lat">3</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Proteaze-lat" title="Шаблон:Proteaze-lat">4</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Ugljenik-azot_ne-peptidne_hidrolaze-lat" class="mw-redirect" title="Шаблон:Ugljenik-azot ne-peptidne hidrolaze-lat">5</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Hidrolaze_kiselinskih_anhidrida-lat" title="Шаблон:Hidrolaze kiselinskih anhidrida-lat">6</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Ugljenik-ugljenik_hidrolaze-lat" class="mw-redirect" title="Шаблон:Ugljenik-ugljenik hidrolaze-lat">7</a>, <a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Proteinske_tirozinske_fosfataze-lat" title="Шаблон:Proteinske tirozinske fosfataze-lat">3.1.3.48</a>, <a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Serinske_endopeptidaze-lat" title="Шаблон:Serinske endopeptidaze-lat">3.4.21</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Cisteinske_proteaze-lat" title="Шаблон:Cisteinske proteaze-lat">22</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Proteaze_asparaginske_kiseline-lat" class="mw-redirect" title="Шаблон:Proteaze asparaginske kiseline-lat">23</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Metaloendopeptidaze-lat" title="Шаблон:Metaloendopeptidaze-lat">24</a>, <a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Ugljenik-ugljenik_liaze-lat" class="mw-redirect" title="Шаблон:Ugljenik-ugljenik liaze-lat">4.1</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Ugljenik-kiseonik_liaze-lat" class="mw-redirect" title="Шаблон:Ugljenik-kiseonik liaze-lat">2</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Ugljenik-azot_liaze-lat" title="Шаблон:Ugljenik-azot liaze-lat">3</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Ugljenik-sumpor_liaze-lat" class="mw-redirect" title="Шаблон:Ugljenik-sumpor liaze-lat">4</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Ugljenik-halid_liaze-lat" class="mw-redirect" title="Шаблон:Ugljenik-halid liaze-lat">5</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Fosfor-kiseonik_liaze-lat" title="Шаблон:Fosfor-kiseonik liaze-lat">6</a>, <a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Racemaze_i_epimeraze-lat" title="Шаблон:Racemaze i epimeraze-lat">5.1</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Geometrijske_izomeraze-lat" title="Шаблон:Geometrijske izomeraze-lat">2</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Intramolekularne_oksidoreduktaze-lat" title="Шаблон:Intramolekularne oksidoreduktaze-lat">3</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Mutaze-lat" title="Шаблон:Mutaze-lat">4</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Topoizomeraze-lat" title="Шаблон:Topoizomeraze-lat">99</a>, <a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Ligaze_CO_CS_i_CN-lat" title="Шаблон:Ligaze CO CS i CN-lat">6.1-3</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Ugljenik-ugljenik_ligaze-lat" class="mw-redirect" title="Шаблон:Ugljenik-ugljenik ligaze-lat">4</a>/<a href="/wiki/%D0%A8%D0%B0%D0%B1%D0%BB%D0%BE%D0%BD:Fosforni_estar_i_azot-metal_ligaze-lat" title="Шаблон:Fosforni estar i azot-metal ligaze-lat">5-6</a></i></li></ul> </div></td></tr></tbody></table></div> <style data-mw-deduplicate="TemplateStyles:r26481770">.mw-parser-output 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