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accesskey="z"><span>メインページ</span></a></li><li id="n-portal" class="mw-list-item"><a href="/wiki/Wikipedia:%E3%82%B3%E3%83%9F%E3%83%A5%E3%83%8B%E3%83%86%E3%82%A3%E3%83%BB%E3%83%9D%E3%83%BC%E3%82%BF%E3%83%AB" title="このプロジェクトについて、できること、情報を入手する場所"><span>コミュニティ・ポータル</span></a></li><li id="n-currentevents" class="mw-list-item"><a href="/wiki/Portal:%E6%9C%80%E8%BF%91%E3%81%AE%E5%87%BA%E6%9D%A5%E4%BA%8B" title="最近の出来事の背景を知る"><span>最近の出来事</span></a></li><li id="n-newpages" class="mw-list-item"><a href="/wiki/%E7%89%B9%E5%88%A5:%E6%96%B0%E3%81%97%E3%81%84%E3%83%9A%E3%83%BC%E3%82%B8" title="最近新規に作成されたページの一覧"><span>新しいページ</span></a></li><li id="n-recentchanges" class="mw-list-item"><a href="/wiki/%E7%89%B9%E5%88%A5:%E6%9C%80%E8%BF%91%E3%81%AE%E6%9B%B4%E6%96%B0" title="このウィキにおける最近の更新の一覧 [r]" accesskey="r"><span>最近の更新</span></a></li><li id="n-randompage" class="mw-list-item"><a href="/wiki/%E7%89%B9%E5%88%A5:%E3%81%8A%E3%81%BE%E3%81%8B%E3%81%9B%E8%A1%A8%E7%A4%BA" title="無作為に選択されたページを読み込む [x]" 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0.875em;"> </span> </a> </div> <div class="vector-header-end"> <div id="p-search" role="search" class="vector-search-box-vue vector-search-box-collapses vector-search-box-show-thumbnail vector-search-box-auto-expand-width vector-search-box"> <a href="/wiki/%E7%89%B9%E5%88%A5:%E6%A4%9C%E7%B4%A2" class="cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only search-toggle" title="Wikipedia内を検索 [f]" accesskey="f"><span class="vector-icon mw-ui-icon-search mw-ui-icon-wikimedia-search"></span> <span>検索</span> </a> <div class="vector-typeahead-search-container"> <div class="cdx-typeahead-search cdx-typeahead-search--show-thumbnail cdx-typeahead-search--auto-expand-width"> <form action="/w/index.php" id="searchform" class="cdx-search-input cdx-search-input--has-end-button"> <div id="simpleSearch" class="cdx-search-input__input-wrapper" data-search-loc="header-moved"> <div class="cdx-text-input cdx-text-input--has-start-icon"> <input class="cdx-text-input__input" type="search" name="search" placeholder="Wikipedia内を検索" aria-label="Wikipedia内を検索" autocapitalize="sentences" title="Wikipedia内を検索 [f]" accesskey="f" id="searchInput" > <span class="cdx-text-input__icon cdx-text-input__start-icon"></span> </div> <input type="hidden" name="title" value="特別:検索"> </div> <button class="cdx-button cdx-search-input__end-button">検索</button> </form> </div> </div> </div> <nav class="vector-user-links vector-user-links-wide" aria-label="個人用ツール"> <div class="vector-user-links-main"> <div id="p-vector-user-menu-preferences" class="vector-menu mw-portlet emptyPortlet" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> </ul> </div> </div> <div id="p-vector-user-menu-userpage" class="vector-menu mw-portlet emptyPortlet" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> </ul> </div> </div> <nav class="vector-appearance-landmark" aria-label="表示"> <div id="vector-appearance-dropdown" class="vector-dropdown " title="ページのフォントサイズ、幅、色の外観を変更する" > <input type="checkbox" id="vector-appearance-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-appearance-dropdown" class="vector-dropdown-checkbox " aria-label="表示" > <label id="vector-appearance-dropdown-label" for="vector-appearance-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-appearance mw-ui-icon-wikimedia-appearance"></span> <span class="vector-dropdown-label-text">表示</span> </label> <div class="vector-dropdown-content"> <div id="vector-appearance-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <div id="p-vector-user-menu-notifications" class="vector-menu mw-portlet emptyPortlet" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> </ul> </div> </div> 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href="/w/index.php?title=%E7%89%B9%E5%88%A5:%E3%83%AD%E3%82%B0%E3%82%A4%E3%83%B3&returnto=%E3%83%94%E3%83%9A%E3%83%A9%E3%82%B7%E3%83%AA%E3%83%B3" title="ログインすることを推奨します。ただし、必須ではありません。 [o]" accesskey="o" class=""><span>ログイン</span></a> </li> </ul> </div> </div> </div> <div id="vector-user-links-dropdown" class="vector-dropdown vector-user-menu vector-button-flush-right vector-user-menu-logged-out" title="その他の操作" > <input type="checkbox" id="vector-user-links-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-user-links-dropdown" class="vector-dropdown-checkbox " aria-label="個人用ツール" > <label id="vector-user-links-dropdown-label" for="vector-user-links-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-ellipsis mw-ui-icon-wikimedia-ellipsis"></span> <span class="vector-dropdown-label-text">個人用ツール</span> </label> <div class="vector-dropdown-content"> <div id="p-personal" class="vector-menu mw-portlet mw-portlet-personal user-links-collapsible-item" title="利用者メニュー" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="pt-sitesupport" class="user-links-collapsible-item mw-list-item"><a href="//donate.wikimedia.org/wiki/Special:FundraiserRedirector?utm_source=donate&utm_medium=sidebar&utm_campaign=C13_ja.wikipedia.org&uselang=ja"><span>寄付</span></a></li><li id="pt-createaccount" class="user-links-collapsible-item mw-list-item"><a href="/w/index.php?title=%E7%89%B9%E5%88%A5:%E3%82%A2%E3%82%AB%E3%82%A6%E3%83%B3%E3%83%88%E4%BD%9C%E6%88%90&returnto=%E3%83%94%E3%83%9A%E3%83%A9%E3%82%B7%E3%83%AA%E3%83%B3" title="アカウントを作成してログインすることをお勧めしますが、必須ではありません"><span class="vector-icon mw-ui-icon-userAdd mw-ui-icon-wikimedia-userAdd"></span> <span>アカウント作成</span></a></li><li id="pt-login" class="user-links-collapsible-item mw-list-item"><a href="/w/index.php?title=%E7%89%B9%E5%88%A5:%E3%83%AD%E3%82%B0%E3%82%A4%E3%83%B3&returnto=%E3%83%94%E3%83%9A%E3%83%A9%E3%82%B7%E3%83%AA%E3%83%B3" title="ログインすることを推奨します。ただし、必須ではありません。 [o]" accesskey="o"><span class="vector-icon mw-ui-icon-logIn mw-ui-icon-wikimedia-logIn"></span> <span>ログイン</span></a></li> </ul> </div> </div> <div id="p-user-menu-anon-editor" class="vector-menu mw-portlet mw-portlet-user-menu-anon-editor" > <div class="vector-menu-heading"> ログアウトした編集者のページ <a href="/wiki/Wikipedia:%E3%82%A6%E3%82%A3%E3%82%AD%E3%83%9A%E3%83%87%E3%82%A3%E3%82%A2%E3%81%B8%E3%82%88%E3%81%86%E3%81%93%E3%81%9D" aria-label="編集の詳細"><span>もっと詳しく</span></a> </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="pt-anoncontribs" class="mw-list-item"><a href="/wiki/%E7%89%B9%E5%88%A5:%E8%87%AA%E5%88%86%E3%81%AE%E6%8A%95%E7%A8%BF%E8%A8%98%E9%8C%B2" title="このIPアドレスからなされた編集の一覧 [y]" accesskey="y"><span>投稿記録</span></a></li><li id="pt-anontalk" class="mw-list-item"><a href="/wiki/%E7%89%B9%E5%88%A5:%E3%83%88%E3%83%BC%E3%82%AF%E3%83%9A%E3%83%BC%E3%82%B8" title="このIPアドレスからなされた編集についての議論 [n]" accesskey="n"><span>トーク</span></a></li> </ul> </div> </div> </div> </div> </nav> </div> </header> </div> <div class="mw-page-container"> <div class="mw-page-container-inner"> <div class="vector-sitenotice-container"> <div id="siteNotice"></div> </div> <div class="vector-column-start"> <div class="vector-main-menu-container"> <div id="mw-navigation"> <nav id="mw-panel" class="vector-main-menu-landmark" aria-label="サイト"> <div id="vector-main-menu-pinned-container" class="vector-pinned-container"> </div> </nav> </div> </div> <div class="vector-sticky-pinned-container"> <nav id="mw-panel-toc" aria-label="目次" data-event-name="ui.sidebar-toc" class="mw-table-of-contents-container vector-toc-landmark"> <div id="vector-toc-pinned-container" class="vector-pinned-container"> <div id="vector-toc" class="vector-toc vector-pinnable-element"> <div class="vector-pinnable-header vector-toc-pinnable-header vector-pinnable-header-pinned" data-feature-name="toc-pinned" data-pinnable-element-id="vector-toc" > <h2 class="vector-pinnable-header-label">目次</h2> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-toc.pin">サイドバーに移動</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-toc.unpin">非表示</button> </div> <ul class="vector-toc-contents" id="mw-panel-toc-list"> <li id="toc-mw-content-text" class="vector-toc-list-item vector-toc-level-1"> <a href="#" class="vector-toc-link"> <div class="vector-toc-text">ページ先頭</div> </a> </li> <li id="toc-薬理" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#薬理"> <div class="vector-toc-text"> <span class="vector-toc-numb">1</span> <span>薬理</span> </div> </a> <ul id="toc-薬理-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-適応" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#適応"> <div class="vector-toc-text"> <span class="vector-toc-numb">2</span> <span>適応</span> </div> </a> <button aria-controls="toc-適応-sublist" class="cdx-button cdx-button--weight-quiet cdx-button--icon-only vector-toc-toggle"> <span class="vector-icon mw-ui-icon-wikimedia-expand"></span> <span>適応サブセクションを切り替えます</span> </button> <ul id="toc-適応-sublist" class="vector-toc-list"> <li id="toc-適応菌種" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#適応菌種"> <div class="vector-toc-text"> <span class="vector-toc-numb">2.1</span> <span>適応菌種</span> </div> </a> <ul id="toc-適応菌種-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-適応症" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#適応症"> <div class="vector-toc-text"> <span class="vector-toc-numb">2.2</span> <span>適応症</span> </div> </a> <ul id="toc-適応症-sublist" class="vector-toc-list"> </ul> </li> </ul> </li> <li id="toc-副作用" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#副作用"> <div class="vector-toc-text"> <span class="vector-toc-numb">3</span> <span>副作用</span> </div> </a> <ul id="toc-副作用-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-投与" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#投与"> <div class="vector-toc-text"> <span class="vector-toc-numb">4</span> <span>投与</span> </div> </a> <ul id="toc-投与-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-脚注" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#脚注"> <div class="vector-toc-text"> <span class="vector-toc-numb">5</span> <span>脚注</span> </div> </a> <ul id="toc-脚注-sublist" class="vector-toc-list"> </ul> </li> </ul> </div> </div> </nav> </div> </div> <div class="mw-content-container"> <main id="content" class="mw-body"> <header class="mw-body-header vector-page-titlebar"> <nav aria-label="目次" class="vector-toc-landmark"> <div id="vector-page-titlebar-toc" class="vector-dropdown vector-page-titlebar-toc vector-button-flush-left" > <input type="checkbox" id="vector-page-titlebar-toc-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-titlebar-toc" class="vector-dropdown-checkbox " aria-label="目次の表示・非表示を切り替え" > <label id="vector-page-titlebar-toc-label" for="vector-page-titlebar-toc-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-listBullet mw-ui-icon-wikimedia-listBullet"></span> <span class="vector-dropdown-label-text">目次の表示・非表示を切り替え</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-titlebar-toc-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <h1 id="firstHeading" class="firstHeading mw-first-heading"><span class="mw-page-title-main">ピペラシリン</span></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" > <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="特定の記事の別の言語版に移動します。利用可能な言語25件" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-25" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">25の言語版</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-ar mw-list-item"><a href="https://ar.wikipedia.org/wiki/%D8%A8%D8%A7%D9%8A%D8%A8%D9%8A%D8%B1%D8%B3%D9%8A%D9%84%D9%8A%D9%86" title="アラビア語: بايبيرسيلين" lang="ar" hreflang="ar" data-title="بايبيرسيلين" data-language-autonym="العربية" data-language-local-name="アラビア語" class="interlanguage-link-target"><span>العربية</span></a></li><li class="interlanguage-link interwiki-azb mw-list-item"><a href="https://azb.wikipedia.org/wiki/%D9%BE%DB%8C%D9%BE%D8%B1%D8%A7%D8%B3%DB%8C%D9%84%DB%8C%D9%86" title="South Azerbaijani: پیپراسیلین" lang="azb" hreflang="azb" data-title="پیپراسیلین" data-language-autonym="تۆرکجه" data-language-local-name="South Azerbaijani" class="interlanguage-link-target"><span>تۆرکجه</span></a></li><li class="interlanguage-link interwiki-cy mw-list-item"><a href="https://cy.wikipedia.org/wiki/Piperasilin" title="ウェールズ語: Piperasilin" lang="cy" hreflang="cy" data-title="Piperasilin" data-language-autonym="Cymraeg" data-language-local-name="ウェールズ語" class="interlanguage-link-target"><span>Cymraeg</span></a></li><li class="interlanguage-link interwiki-da mw-list-item"><a href="https://da.wikipedia.org/wiki/Piperacillin" title="デンマーク語: Piperacillin" lang="da" hreflang="da" data-title="Piperacillin" data-language-autonym="Dansk" data-language-local-name="デンマーク語" class="interlanguage-link-target"><span>Dansk</span></a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/Piperacillin" title="ドイツ語: Piperacillin" lang="de" hreflang="de" data-title="Piperacillin" data-language-autonym="Deutsch" data-language-local-name="ドイツ語" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-el mw-list-item"><a href="https://el.wikipedia.org/wiki/%CE%A0%CE%B9%CF%80%CE%B5%CF%81%CE%B1%CE%BA%CE%B9%CE%BB%CE%BB%CE%AF%CE%BD%CE%B7" title="ギリシャ語: Πιπερακιλλίνη" lang="el" hreflang="el" data-title="Πιπερακιλλίνη" data-language-autonym="Ελληνικά" data-language-local-name="ギリシャ語" class="interlanguage-link-target"><span>Ελληνικά</span></a></li><li class="interlanguage-link interwiki-en mw-list-item"><a href="https://en.wikipedia.org/wiki/Piperacillin" title="英語: Piperacillin" lang="en" hreflang="en" data-title="Piperacillin" data-language-autonym="English" data-language-local-name="英語" class="interlanguage-link-target"><span>English</span></a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/Piperacilina" title="スペイン語: Piperacilina" lang="es" hreflang="es" data-title="Piperacilina" data-language-autonym="Español" data-language-local-name="スペイン語" class="interlanguage-link-target"><span>Español</span></a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/%D9%BE%DB%8C%D9%BE%D8%B1%D8%A7%D8%B3%DB%8C%D9%84%DB%8C%D9%86" title="ペルシア語: پیپراسیلین" lang="fa" hreflang="fa" data-title="پیپراسیلین" data-language-autonym="فارسی" data-language-local-name="ペルシア語" class="interlanguage-link-target"><span>فارسی</span></a></li><li class="interlanguage-link interwiki-fi mw-list-item"><a href="https://fi.wikipedia.org/wiki/Piperasilliini" title="フィンランド語: Piperasilliini" lang="fi" hreflang="fi" data-title="Piperasilliini" data-language-autonym="Suomi" data-language-local-name="フィンランド語" class="interlanguage-link-target"><span>Suomi</span></a></li><li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/Pip%C3%A9racilline" title="フランス語: Pipéracilline" lang="fr" hreflang="fr" data-title="Pipéracilline" data-language-autonym="Français" data-language-local-name="フランス語" class="interlanguage-link-target"><span>Français</span></a></li><li class="interlanguage-link interwiki-he mw-list-item"><a href="https://he.wikipedia.org/wiki/%D7%A4%D7%99%D7%A4%D7%A8%D7%A6%D7%99%D7%9C%D7%99%D7%9F" title="ヘブライ語: פיפרצילין" lang="he" hreflang="he" data-title="פיפרצילין" data-language-autonym="עברית" data-language-local-name="ヘブライ語" class="interlanguage-link-target"><span>עברית</span></a></li><li class="interlanguage-link interwiki-id mw-list-item"><a href="https://id.wikipedia.org/wiki/Piperasilin" title="インドネシア語: Piperasilin" lang="id" hreflang="id" data-title="Piperasilin" data-language-autonym="Bahasa Indonesia" data-language-local-name="インドネシア語" class="interlanguage-link-target"><span>Bahasa Indonesia</span></a></li><li class="interlanguage-link interwiki-it mw-list-item"><a href="https://it.wikipedia.org/wiki/Piperacillina" title="イタリア語: Piperacillina" lang="it" hreflang="it" data-title="Piperacillina" data-language-autonym="Italiano" data-language-local-name="イタリア語" class="interlanguage-link-target"><span>Italiano</span></a></li><li class="interlanguage-link interwiki-pl mw-list-item"><a href="https://pl.wikipedia.org/wiki/Piperacylina" title="ポーランド語: Piperacylina" lang="pl" hreflang="pl" data-title="Piperacylina" data-language-autonym="Polski" data-language-local-name="ポーランド語" class="interlanguage-link-target"><span>Polski</span></a></li><li class="interlanguage-link interwiki-ro mw-list-item"><a href="https://ro.wikipedia.org/wiki/Piperacilin%C4%83" title="ルーマニア語: Piperacilină" lang="ro" hreflang="ro" data-title="Piperacilină" data-language-autonym="Română" data-language-local-name="ルーマニア語" class="interlanguage-link-target"><span>Română</span></a></li><li class="interlanguage-link interwiki-sh mw-list-item"><a href="https://sh.wikipedia.org/wiki/Piperacilin" title="セルボ・クロアチア語: Piperacilin" lang="sh" hreflang="sh" data-title="Piperacilin" data-language-autonym="Srpskohrvatski / српскохрватски" data-language-local-name="セルボ・クロアチア語" class="interlanguage-link-target"><span>Srpskohrvatski / српскохрватски</span></a></li><li class="interlanguage-link interwiki-sl mw-list-item"><a href="https://sl.wikipedia.org/wiki/Piperacilin" title="スロベニア語: Piperacilin" lang="sl" hreflang="sl" data-title="Piperacilin" data-language-autonym="Slovenščina" data-language-local-name="スロベニア語" class="interlanguage-link-target"><span>Slovenščina</span></a></li><li class="interlanguage-link interwiki-sr mw-list-item"><a href="https://sr.wikipedia.org/wiki/Piperacilin" title="セルビア語: Piperacilin" lang="sr" hreflang="sr" data-title="Piperacilin" data-language-autonym="Српски / srpski" data-language-local-name="セルビア語" class="interlanguage-link-target"><span>Српски / srpski</span></a></li><li class="interlanguage-link interwiki-sv mw-list-item"><a href="https://sv.wikipedia.org/wiki/Piperacillin" title="スウェーデン語: Piperacillin" lang="sv" hreflang="sv" data-title="Piperacillin" data-language-autonym="Svenska" data-language-local-name="スウェーデン語" class="interlanguage-link-target"><span>Svenska</span></a></li><li class="interlanguage-link interwiki-th mw-list-item"><a href="https://th.wikipedia.org/wiki/%E0%B8%9B%E0%B8%B4%E0%B8%9B%E0%B9%80%E0%B8%9B%E0%B8%AD%E0%B8%A3%E0%B8%B2%E0%B8%8B%E0%B8%B4%E0%B8%A5%E0%B8%A5%E0%B8%B4%E0%B8%99" title="タイ語: ปิปเปอราซิลลิน" lang="th" hreflang="th" data-title="ปิปเปอราซิลลิน" data-language-autonym="ไทย" data-language-local-name="タイ語" class="interlanguage-link-target"><span>ไทย</span></a></li><li class="interlanguage-link interwiki-tr mw-list-item"><a href="https://tr.wikipedia.org/wiki/Piperasilin" title="トルコ語: Piperasilin" lang="tr" hreflang="tr" data-title="Piperasilin" data-language-autonym="Türkçe" data-language-local-name="トルコ語" class="interlanguage-link-target"><span>Türkçe</span></a></li><li class="interlanguage-link interwiki-uk mw-list-item"><a href="https://uk.wikipedia.org/wiki/%D0%9F%D1%96%D0%BF%D0%B5%D1%80%D0%B0%D1%86%D0%B8%D0%BB%D1%96%D0%BD" title="ウクライナ語: Піперацилін" lang="uk" hreflang="uk" data-title="Піперацилін" data-language-autonym="Українська" data-language-local-name="ウクライナ語" class="interlanguage-link-target"><span>Українська</span></a></li><li class="interlanguage-link interwiki-wuu mw-list-item"><a href="https://wuu.wikipedia.org/wiki/%E5%93%8C%E6%8B%89%E8%A5%BF%E6%9E%97" title="呉語: 哌拉西林" lang="wuu" hreflang="wuu" data-title="哌拉西林" data-language-autonym="吴语" data-language-local-name="呉語" class="interlanguage-link-target"><span>吴语</span></a></li><li class="interlanguage-link interwiki-zh mw-list-item"><a href="https://zh.wikipedia.org/wiki/%E5%93%8C%E6%8B%89%E8%A5%BF%E6%9E%97" title="中国語: 哌拉西林" lang="zh" hreflang="zh" data-title="哌拉西林" data-language-autonym="中文" data-language-local-name="中国語" class="interlanguage-link-target"><span>中文</span></a></li> </ul> <div class="after-portlet after-portlet-lang"><span class="wb-langlinks-edit wb-langlinks-link"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q423787#sitelinks-wikipedia" title="言語間リンクを編集" class="wbc-editpage">リンクを編集</a></span></div> </div> </div> </div> </header> <div class="vector-page-toolbar"> <div class="vector-page-toolbar-container"> <div id="left-navigation"> <nav aria-label="名前空間"> <div id="p-associated-pages" class="vector-menu vector-menu-tabs mw-portlet mw-portlet-associated-pages" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-nstab-main" class="selected vector-tab-noicon mw-list-item"><a href="/wiki/%E3%83%94%E3%83%9A%E3%83%A9%E3%82%B7%E3%83%AA%E3%83%B3" title="本文を閲覧 [c]" accesskey="c"><span>ページ</span></a></li><li id="ca-talk" class="new vector-tab-noicon mw-list-item"><a href="/w/index.php?title=%E3%83%8E%E3%83%BC%E3%83%88:%E3%83%94%E3%83%9A%E3%83%A9%E3%82%B7%E3%83%AA%E3%83%B3&action=edit&redlink=1" rel="discussion" class="new" title="「本文ページについての議論」 (存在しないページ) [t]" accesskey="t"><span>ノート</span></a></li> </ul> </div> </div> <div id="vector-variants-dropdown" class="vector-dropdown emptyPortlet" > <input type="checkbox" id="vector-variants-dropdown-checkbox" role="button" aria-haspopup="true" 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for="vector-page-tools-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet" aria-hidden="true" ><span class="vector-dropdown-label-text">ツール</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-tools-unpinned-container" class="vector-unpinned-container"> <div id="vector-page-tools" class="vector-page-tools vector-pinnable-element"> <div class="vector-pinnable-header vector-page-tools-pinnable-header vector-pinnable-header-unpinned" data-feature-name="page-tools-pinned" data-pinnable-element-id="vector-page-tools" data-pinned-container-id="vector-page-tools-pinned-container" data-unpinned-container-id="vector-page-tools-unpinned-container" > <div class="vector-pinnable-header-label">ツール</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-page-tools.pin">サイドバーに移動</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-page-tools.unpin">非表示</button> </div> <div id="p-cactions" class="vector-menu mw-portlet mw-portlet-cactions emptyPortlet vector-has-collapsible-items" title="その他の操作" > <div class="vector-menu-heading"> 操作 </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-more-view" class="selected vector-more-collapsible-item mw-list-item"><a href="/wiki/%E3%83%94%E3%83%9A%E3%83%A9%E3%82%B7%E3%83%AA%E3%83%B3"><span>閲覧</span></a></li><li id="ca-more-edit" class="vector-more-collapsible-item mw-list-item"><a href="/w/index.php?title=%E3%83%94%E3%83%9A%E3%83%A9%E3%82%B7%E3%83%AA%E3%83%B3&action=edit" title="このページのソースコードを編集する [e]" accesskey="e"><span>編集</span></a></li><li id="ca-more-history" class="vector-more-collapsible-item mw-list-item"><a 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href="/w/index.php?title=%E7%89%B9%E5%88%A5:%E3%81%93%E3%81%AE%E3%83%9A%E3%83%BC%E3%82%B8%E3%82%92%E5%BC%95%E7%94%A8&page=%E3%83%94%E3%83%9A%E3%83%A9%E3%82%B7%E3%83%AA%E3%83%B3&id=101978455&wpFormIdentifier=titleform" title="このページの引用方法"><span>このページを引用</span></a></li><li id="t-urlshortener" class="mw-list-item"><a href="/w/index.php?title=%E7%89%B9%E5%88%A5:UrlShortener&url=https%3A%2F%2Fja.wikipedia.org%2Fwiki%2F%25E3%2583%2594%25E3%2583%259A%25E3%2583%25A9%25E3%2582%25B7%25E3%2583%25AA%25E3%2583%25B3"><span>短縮URLを取得する</span></a></li><li id="t-urlshortener-qrcode" class="mw-list-item"><a href="/w/index.php?title=%E7%89%B9%E5%88%A5:QrCode&url=https%3A%2F%2Fja.wikipedia.org%2Fwiki%2F%25E3%2583%2594%25E3%2583%259A%25E3%2583%25A9%25E3%2582%25B7%25E3%2583%25AA%25E3%2583%25B3"><span>QRコードをダウンロード</span></a></li> </ul> </div> </div> <div id="p-coll-print_export" class="vector-menu mw-portlet mw-portlet-coll-print_export" > <div class="vector-menu-heading"> 印刷/書き出し </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="coll-create_a_book" class="mw-list-item"><a href="/w/index.php?title=%E7%89%B9%E5%88%A5:%E3%83%96%E3%83%83%E3%82%AF&bookcmd=book_creator&referer=%E3%83%94%E3%83%9A%E3%83%A9%E3%82%B7%E3%83%AA%E3%83%B3"><span>ブックの新規作成</span></a></li><li id="coll-download-as-rl" class="mw-list-item"><a href="/w/index.php?title=%E7%89%B9%E5%88%A5:DownloadAsPdf&page=%E3%83%94%E3%83%9A%E3%83%A9%E3%82%B7%E3%83%AA%E3%83%B3&action=show-download-screen"><span>PDF 形式でダウンロード</span></a></li><li id="t-print" class="mw-list-item"><a href="/w/index.php?title=%E3%83%94%E3%83%9A%E3%83%A9%E3%82%B7%E3%83%AA%E3%83%B3&printable=yes" title="このページの印刷用ページ [p]" accesskey="p"><span>印刷用バージョン</span></a></li> </ul> </div> </div> <div id="p-wikibase-otherprojects" class="vector-menu mw-portlet mw-portlet-wikibase-otherprojects" > <div class="vector-menu-heading"> 他のプロジェクト </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="wb-otherproject-link wb-otherproject-commons mw-list-item"><a href="https://commons.wikimedia.org/wiki/Category:Piperacillin" hreflang="en"><span>コモンズ</span></a></li><li id="t-wikibase" class="wb-otherproject-link wb-otherproject-wikibase-dataitem mw-list-item"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q423787" title="関連付けられたデータリポジトリ項目へのリンク [g]" accesskey="g"><span>ウィキデータ項目</span></a></li> </ul> </div> </div> </div> </div> </div> </div> </nav> </div> </div> </div> <div class="vector-column-end"> <div class="vector-sticky-pinned-container"> <nav class="vector-page-tools-landmark" aria-label="ページツール"> <div id="vector-page-tools-pinned-container" class="vector-pinned-container"> </div> </nav> <nav class="vector-appearance-landmark" aria-label="表示"> <div id="vector-appearance-pinned-container" class="vector-pinned-container"> <div id="vector-appearance" class="vector-appearance vector-pinnable-element"> <div class="vector-pinnable-header vector-appearance-pinnable-header vector-pinnable-header-pinned" data-feature-name="appearance-pinned" data-pinnable-element-id="vector-appearance" data-pinned-container-id="vector-appearance-pinned-container" data-unpinned-container-id="vector-appearance-unpinned-container" > <div class="vector-pinnable-header-label">表示</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-appearance.pin">サイドバーに移動</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-appearance.unpin">非表示</button> </div> </div> </div> </nav> </div> </div> <div id="bodyContent" class="vector-body" aria-labelledby="firstHeading" data-mw-ve-target-container> <div class="vector-body-before-content"> <div class="mw-indicators"> </div> <div id="siteSub" class="noprint">出典: フリー百科事典『ウィキペディア（Wikipedia）』</div> </div> <div id="contentSub"><div id="mw-content-subtitle"></div></div> <div id="mw-content-text" class="mw-body-content"><div class="mw-content-ltr mw-parser-output" lang="ja" dir="ltr"><table class="infobox" style="width:22em; border-spacing:2px;"><caption itemprop="name" class="" style="">ピペラシリン</caption><tbody><tr class="" style="" itemprop=""><td colspan="2" class="" style="text-align:center;" itemprop=""> <span class="mw-default-size" typeof="mw:File/Frameless"><a href="/wiki/%E3%83%95%E3%82%A1%E3%82%A4%E3%83%AB:Piperacillin.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/8/87/Piperacillin.svg/220px-Piperacillin.svg.png" decoding="async" width="220" height="243" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/8/87/Piperacillin.svg/330px-Piperacillin.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/8/87/Piperacillin.svg/440px-Piperacillin.svg.png 2x" data-file-width="706" data-file-height="781" /></a></span></td></tr><tr style=""><th scope="col" colspan="2" class="" style="text-align:center; background:#ddd"><a href="/wiki/IUPAC%E5%91%BD%E5%90%8D%E6%B3%95" title="IUPAC命名法">IUPAC命名法</a>による物質名</th></tr><tr class="" style="" itemprop=""><td colspan="2" class="" style="text-align:center;" itemprop=""> <div class="NavFrame collapsed" style="border: none; padding: 0;"> <div class="NavHead" style="font-size: 105%; background: transparent; text-align: left;"><a href="/wiki/IUPAC%E5%91%BD%E5%90%8D%E6%B3%95" title="IUPAC命名法">IUPAC名</a></div> <ul class="NavContent" style="list-style: none none; margin-left: 0; font-size: 0.95em!important; padding-left:2em; text-align: left; text-indent:-2em; word-break:break-all; font-size: 105%; margin-top: 0; margin-bottom: 0; line-height: inherit;"><li style="line-height: inherit; margin: 0">(2<i>S</i>,5<i>R</i>,6<i>R</i>)-6-{[(2<i>R</i>)-2-[(4-ethyl-2,3-dioxo-piperazine-1-carbonyl)amino]-2-phenyl-acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid</li></ul> </div></td></tr><tr style=""><th scope="col" colspan="2" class="" style="text-align:center; background:#ddd">臨床データ</th></tr><tr class="" style="" itemprop=""><th scope="row" style="text-align:left; white-space:nowrap; padding:0.1em 0;line-height:1.2em; white-space:nowrap;"><a href="/wiki/%E5%95%86%E5%8F%B7" title="商号">販売名</a></th><td class="" style="" itemprop=""> ペントシリン, Pipracil</td></tr><tr class="" style="" itemprop=""><th scope="row" style="text-align:left; white-space:nowrap; padding:0.1em 0;line-height:1.2em; white-space:nowrap;"><a href="https://en.wikipedia.org/wiki/Drugs.com" class="extiw" title="en:Drugs.com">Drugs.com</a></th><td class="" style="" itemprop=""> <span class="reflink plainlinks nourlexpansion"><a rel="nofollow" class="external text" href="https://www.drugs.com/cdi/piperacillin.html">患者向け情報(英語)<br />Consumer Drug Information</a></span></td></tr><tr class="" style="" itemprop=""><th scope="row" style="text-align:left; white-space:nowrap; padding:0.1em 0;line-height:1.2em; white-space:nowrap;"><a href="/wiki/%E8%83%8E%E5%85%90%E5%8D%B1%E9%99%BA%E5%BA%A6%E5%88%86%E9%A1%9E" title="胎児危険度分類">胎児危険度分類</a></th><td class="" style="" itemprop=""> <div class="plainlist"> <ul><li>B</li></ul> </div></td></tr><tr class="" style="" itemprop=""><th scope="row" style="text-align:left; white-space:nowrap; padding:0.1em 0;line-height:1.2em; white-space:nowrap;"><a href="/wiki/%E5%8C%BB%E7%99%82%E5%93%81%E8%A6%8F%E5%88%B6" title="医療品規制">法的規制</a></th><td class="" style="" itemprop=""> <div class="plainlist"> <ul><li><small><abbr title="日本">JP</abbr></small>: 処方箋医薬品 </li> <li><small><abbr title="イギリス">UK</abbr>:</small> <a href="/wiki/%E5%87%A6%E6%96%B9%E7%AE%8B%E5%8C%BB%E8%96%AC%E5%93%81" title="処方箋医薬品">処方箋のみ</a> (POM) </li> <li><small><abbr title="アメリカ合衆国">US</abbr>:</small> <a href="/wiki/%E5%87%A6%E6%96%B9%E7%AE%8B%E5%8C%BB%E8%96%AC%E5%93%81" title="処方箋医薬品"><span lang="en"><span class="Unicode">℞</span>-only</span></a> </li></ul></div></td></tr><tr style=""><th scope="col" colspan="2" class="" style="text-align:center; background:#ddd"><a href="/wiki/%E8%96%AC%E7%89%A9%E5%8B%95%E6%85%8B%E5%AD%A6" title="薬物動態学">薬物動態</a>データ</th></tr><tr><th scope="row" style="text-align:left;white-space:nowrap;padding:0.1em 0; line-height:1.2em; white-space:nowrap;"><a href="/wiki/%E7%94%9F%E7%89%A9%E5%AD%A6%E7%9A%84%E5%88%A9%E7%94%A8%E8%83%BD" class="mw-redirect" title="生物学的利用能">生物学的利用能</a></th><td>経口投与では0%</td></tr><tr><th scope="row" style="text-align:left;white-space:nowrap;padding:0.1em 0; line-height:1.2em; white-space:nowrap;"><a href="/wiki/%E8%A1%80%E6%BC%BF%E3%82%BF%E3%83%B3%E3%83%91%E3%82%AF%E7%B5%90%E5%90%88" title="血漿タンパク結合">血漿タンパク結合</a></th><td>30%</td></tr><tr><th scope="row" style="text-align:left;white-space:nowrap;padding:0.1em 0; line-height:1.2em; white-space:nowrap;"><a href="/wiki/%E8%96%AC%E7%89%A9%E4%BB%A3%E8%AC%9D" title="薬物代謝">代謝</a></th><td>多くが代謝されない</td></tr><tr><th scope="row" style="text-align:left;white-space:nowrap;padding:0.1em 0; line-height:1.2em; white-space:nowrap;"><a href="/wiki/%E5%8D%8A%E6%B8%9B%E6%9C%9F_(%E8%96%AC%E5%AD%A6)" title="半減期 (薬学)">半減期</a></th><td>36–72 分</td></tr><tr><th scope="row" style="text-align:left;white-space:nowrap;padding:0.1em 0; line-height:1.2em; white-space:nowrap;"><a href="/wiki/%E6%8E%92%E6%B3%84" title="排泄">排泄</a></th><td>20% 胆汁, 80% が未変化体で尿中</td></tr><tr style=""><th scope="col" colspan="2" class="" style="text-align:center; background:#ddd">データベースID</th></tr><tr class="" style="" itemprop=""><th scope="row" style="text-align:left; white-space:nowrap; padding:0.1em 0;line-height:1.2em; white-space:nowrap;"><a href="/wiki/CAS%E7%99%BB%E9%8C%B2%E7%95%AA%E5%8F%B7" title="CAS登録番号">CAS番号</a><br /></th><td class="" style="" itemprop=""> <span title="www.commonchemistry.org"><a rel="nofollow" class="external text" href="https://commonchemistry.cas.org/detail?cas_rn=61477-96-1">61477-96-1</a></span><sup> <span typeof="mw:File"><a href="/wiki/%E3%83%95%E3%82%A1%E3%82%A4%E3%83%AB:Antu_mail-mark-notjunk.svg" class="mw-file-description" title="チェック"><img alt="チェック" src="//upload.wikimedia.org/wikipedia/commons/thumb/b/b1/Antu_mail-mark-notjunk.svg/7px-Antu_mail-mark-notjunk.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/b/b1/Antu_mail-mark-notjunk.svg/11px-Antu_mail-mark-notjunk.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/b/b1/Antu_mail-mark-notjunk.svg/14px-Antu_mail-mark-notjunk.svg.png 2x" data-file-width="512" data-file-height="512" /></a></span></sup></td></tr><tr class="" style="" itemprop=""><th scope="row" style="text-align:left; white-space:nowrap; padding:0.1em 0;line-height:1.2em; white-space:nowrap;"><a href="/wiki/%E8%A7%A3%E5%89%96%E6%B2%BB%E7%99%82%E5%8C%96%E5%AD%A6%E5%88%86%E9%A1%9E%E6%B3%95" title="解剖治療化学分類法">ATCコード</a></th><td class="" style="" itemprop=""> <a href="https://en.wikipedia.org/wiki/ATC_code_J01" class="extiw" title="en:ATC code J01">J01CA12</a> (<span title="www.whocc.no"><a rel="nofollow" class="external text" href="https://atcddd.fhi.no/atc_ddd_index/?code=J01CA12">WHO</a></span>) </td></tr><tr class="" style="" itemprop=""><th scope="row" style="text-align:left; white-space:nowrap; padding:0.1em 0;line-height:1.2em; white-space:nowrap;"><a href="/wiki/PubChem" title="PubChem">PubChem</a></th><td class="" style="" itemprop=""> CID: <span class="reflink plainlinks nourlexpansion"><a rel="nofollow" class="external text" href="https://pubchem.ncbi.nlm.nih.gov/compound/43672">43672</a></span></td></tr><tr class="" style="" itemprop=""><th scope="row" style="text-align:left; white-space:nowrap; padding:0.1em 0;line-height:1.2em; white-space:nowrap;"><span title="リンク先の項目はまだありません。新規の執筆や他言語版からの翻訳が望まれます。"><a href="/w/index.php?title=IUPHAR/BPS_Guide_to_PHARMACOLOGY&action=edit&redlink=1" class="new" title="「IUPHAR/BPS Guide to PHARMACOLOGY」 (存在しないページ)">IUPHAR/BPS</a><span style="font-size: 0.77em; font-weight: normal;" class="noprint">（<a href="https://en.wikipedia.org/wiki/Guide_to_Pharmacology" class="extiw" title="en:Guide to Pharmacology">英語版</a>）</span></span></th><td class="" style="" itemprop=""> <span class="reflink plainlinks nourlexpansion"><a rel="nofollow" class="external text" href="https://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=422">422</a></span></td></tr><tr class="" style="" itemprop=""><th scope="row" style="text-align:left; white-space:nowrap; padding:0.1em 0;line-height:1.2em; white-space:nowrap;"><a href="/wiki/DrugBank" title="DrugBank">DrugBank</a></th><td class="" style="" itemprop=""> <span class="reflink plainlinks nourlexpansion"><a rel="nofollow" class="external text" href="https://go.drugbank.com/drugs/DB00319">DB00319</a></span><sup> <span typeof="mw:File"><a href="/wiki/%E3%83%95%E3%82%A1%E3%82%A4%E3%83%AB:Antu_mail-mark-notjunk.svg" class="mw-file-description" title="チェック"><img alt="チェック" src="//upload.wikimedia.org/wikipedia/commons/thumb/b/b1/Antu_mail-mark-notjunk.svg/7px-Antu_mail-mark-notjunk.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/b/b1/Antu_mail-mark-notjunk.svg/11px-Antu_mail-mark-notjunk.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/b/b1/Antu_mail-mark-notjunk.svg/14px-Antu_mail-mark-notjunk.svg.png 2x" data-file-width="512" data-file-height="512" /></a></span></sup></td></tr><tr class="" style="" itemprop=""><th scope="row" style="text-align:left; white-space:nowrap; padding:0.1em 0;line-height:1.2em; white-space:nowrap;"><a href="/wiki/ChemSpider" title="ChemSpider">ChemSpider</a></th><td class="" style="" itemprop=""> <span class="reflink plainlinks nourlexpansion"><a rel="nofollow" class="external text" href="https://www.chemspider.com/Chemical-Structure.39798.html">39798</a></span><sup> <span typeof="mw:File"><a href="/wiki/%E3%83%95%E3%82%A1%E3%82%A4%E3%83%AB:Antu_mail-mark-notjunk.svg" class="mw-file-description" title="チェック"><img alt="チェック" src="//upload.wikimedia.org/wikipedia/commons/thumb/b/b1/Antu_mail-mark-notjunk.svg/7px-Antu_mail-mark-notjunk.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/b/b1/Antu_mail-mark-notjunk.svg/11px-Antu_mail-mark-notjunk.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/b/b1/Antu_mail-mark-notjunk.svg/14px-Antu_mail-mark-notjunk.svg.png 2x" data-file-width="512" data-file-height="512" /></a></span></sup></td></tr><tr class="" style="" itemprop=""><th scope="row" style="text-align:left; white-space:nowrap; padding:0.1em 0;line-height:1.2em; white-space:nowrap;"><a href="/wiki/Unique_Ingredient_Identifier" title="Unique Ingredient Identifier">UNII</a></th><td class="" style="" itemprop=""> <span class="reflink plainlinks nourlexpansion"><a rel="nofollow" class="external text" href="https://precision.fda.gov/uniisearch/srs/unii/9I628532GX">9I628532GX</a></span><sup> <span typeof="mw:File"><a href="/wiki/%E3%83%95%E3%82%A1%E3%82%A4%E3%83%AB:Antu_mail-mark-notjunk.svg" class="mw-file-description" title="チェック"><img alt="チェック" src="//upload.wikimedia.org/wikipedia/commons/thumb/b/b1/Antu_mail-mark-notjunk.svg/7px-Antu_mail-mark-notjunk.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/b/b1/Antu_mail-mark-notjunk.svg/11px-Antu_mail-mark-notjunk.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/b/b1/Antu_mail-mark-notjunk.svg/14px-Antu_mail-mark-notjunk.svg.png 2x" data-file-width="512" data-file-height="512" /></a></span></sup></td></tr><tr class="" style="" itemprop=""><th scope="row" style="text-align:left; white-space:nowrap; padding:0.1em 0;line-height:1.2em; white-space:nowrap;"><a href="/wiki/KEGG" title="KEGG">KEGG</a></th><td class="" style="" itemprop=""> <span class="reflink plainlinks nourlexpansion"><a rel="nofollow" class="external text" href="https://www.kegg.jp/entry/D08380">D08380</a> </span> <sup> <span typeof="mw:File"><a href="/wiki/%E3%83%95%E3%82%A1%E3%82%A4%E3%83%AB:Antu_mail-mark-notjunk.svg" class="mw-file-description" title="チェック"><img alt="チェック" src="//upload.wikimedia.org/wikipedia/commons/thumb/b/b1/Antu_mail-mark-notjunk.svg/7px-Antu_mail-mark-notjunk.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/b/b1/Antu_mail-mark-notjunk.svg/11px-Antu_mail-mark-notjunk.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/b/b1/Antu_mail-mark-notjunk.svg/14px-Antu_mail-mark-notjunk.svg.png 2x" data-file-width="512" data-file-height="512" /></a></span></sup></td></tr><tr class="" style="" itemprop=""><th scope="row" style="text-align:left; white-space:nowrap; padding:0.1em 0;line-height:1.2em; white-space:nowrap;"><a href="/wiki/ChEBI" title="ChEBI">ChEBI</a></th><td class="" style="" itemprop=""> <span class="reflink plainlinks nourlexpansion"><a rel="nofollow" class="external text" href="https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:8232">CHEBI:8232</a></span><sup> <span typeof="mw:File"><a href="/wiki/%E3%83%95%E3%82%A1%E3%82%A4%E3%83%AB:Antu_mail-mark-notjunk.svg" class="mw-file-description" title="チェック"><img alt="チェック" src="//upload.wikimedia.org/wikipedia/commons/thumb/b/b1/Antu_mail-mark-notjunk.svg/7px-Antu_mail-mark-notjunk.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/b/b1/Antu_mail-mark-notjunk.svg/11px-Antu_mail-mark-notjunk.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/b/b1/Antu_mail-mark-notjunk.svg/14px-Antu_mail-mark-notjunk.svg.png 2x" data-file-width="512" data-file-height="512" /></a></span></sup></td></tr><tr class="" style="" itemprop=""><th scope="row" style="text-align:left; white-space:nowrap; padding:0.1em 0;line-height:1.2em; white-space:nowrap;"><a href="/wiki/%E3%82%B1%E3%83%B3%E3%83%96%E3%83%AB" title="ケンブル">ChEMBL</a></th><td class="" style="" itemprop=""> <span class="reflink plainlinks nourlexpansion"><a rel="nofollow" class="external text" href="https://www.ebi.ac.uk/chembldb/index.php/compound/inspect/CHEMBL702">CHEMBL702</a></span></td></tr><tr style=""><th scope="col" colspan="2" class="" style="text-align:center; background:#ddd">化学的データ</th></tr><tr><th scope="row" style="text-align:left;white-space:nowrap;padding:0.1em 0; line-height:1.2em; white-space:nowrap;"><a href="/wiki/%E5%88%86%E5%AD%90%E9%87%8F" title="分子量">分子量</a></th><td>517.555 g/mol</td></tr><tr><td colspan="2" style="text-align:center"><div class="NavFrame collapsed" style="border: none; padding: 0;"> <div class="NavHead" style="font-size: 105%; background: transparent; text-align: left;"><a href="/wiki/SMILES%E8%A8%98%E6%B3%95" title="SMILES記法">SMILES</a></div> <ul class="NavContent" style="list-style: none none; margin-left: 0; font-size: 0.95em!important; padding-left:2em; text-align: left; text-indent:-2em; word-break:break-all; font-size: 105%; margin-top: 0; margin-bottom: 0; line-height: inherit;"><li style="line-height: inherit; margin: 0">O=C(O)[C@@H]3N4C(=O)[C@@H](NC(=O)[C@@H](c1ccccc1)NC(=O)N2C(=O)C(=O)N(CC)CC2)[C@H]4SC3(C)C</li></ul> </div></td></tr><tr><td colspan="2" style="text-align:center"><div class="NavFrame collapsed" style="border: none; padding: 0;"> <div class="NavHead" style="font-size: 105%; background: transparent; text-align: left;"><a href="/wiki/InChI" title="InChI">InChI</a></div> <ul class="NavContent" style="list-style: none none; margin-left: 0; font-size: 0.95em!important; padding-left:2em; text-align: left; text-indent:-2em; word-break:break-all; font-size: 105%; margin-top: 0; margin-bottom: 0; line-height: inherit;"><li style="line-height: inherit; margin: 0">InChI=1S/C23H27N5O7S/c1-4-26-10-11-27(19(32)18(26)31)22(35)25-13(12-8-6-5-7-9-12)16(29)24-14-17(30)28-15(21(33)34)23(2,3)36-20(14)28/h5-9,13-15,20H,4,10-11H2,1-3H3,(H,24,29)(H,25,35)(H,33,34)/t13-,14-,15+,20-/m1/s1<sup> <span typeof="mw:File"><a href="/wiki/%E3%83%95%E3%82%A1%E3%82%A4%E3%83%AB:Antu_mail-mark-notjunk.svg" class="mw-file-description" title="チェック"><img alt="チェック" src="//upload.wikimedia.org/wikipedia/commons/thumb/b/b1/Antu_mail-mark-notjunk.svg/7px-Antu_mail-mark-notjunk.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/b/b1/Antu_mail-mark-notjunk.svg/11px-Antu_mail-mark-notjunk.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/b/b1/Antu_mail-mark-notjunk.svg/14px-Antu_mail-mark-notjunk.svg.png 2x" data-file-width="512" data-file-height="512" /></a></span></sup></li><li style="line-height: inherit; margin: 0">Key:IVBHGBMCVLDMKU-GXNBUGAJSA-N<sup> <span typeof="mw:File"><a href="/wiki/%E3%83%95%E3%82%A1%E3%82%A4%E3%83%AB:Antu_mail-mark-notjunk.svg" class="mw-file-description" title="チェック"><img alt="チェック" src="//upload.wikimedia.org/wikipedia/commons/thumb/b/b1/Antu_mail-mark-notjunk.svg/7px-Antu_mail-mark-notjunk.svg.png" decoding="async" width="7" height="7" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/b/b1/Antu_mail-mark-notjunk.svg/11px-Antu_mail-mark-notjunk.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/b/b1/Antu_mail-mark-notjunk.svg/14px-Antu_mail-mark-notjunk.svg.png 2x" data-file-width="512" data-file-height="512" /></a></span></sup></li></ul> </div></td></tr><tr class="noprint"><td colspan="2" style="text-align:right; font-size:85%;"><a href="/wiki/Template:Drugbox" title="Template:Drugbox">テンプレートを表示</a></td></tr></tbody></table> <p><b>ピペラシリン</b>(Piperacillin)は広域スペクトラムの <a href="/wiki/%CE%92-%E3%83%A9%E3%82%AF%E3%82%BF%E3%83%A0%E7%B3%BB%E6%8A%97%E7%94%9F%E7%89%A9%E8%B3%AA" title="Β-ラクタム系抗生物質">β-ラクタム抗生物質</a> 、中でも<a href="/w/index.php?title=%E3%82%A6%E3%83%AC%E3%82%A4%E3%83%89%E3%83%9A%E3%83%8B%E3%82%B7%E3%83%AA%E3%83%B3&action=edit&redlink=1" class="new" title="「ウレイドペニシリン」 (存在しないページ)">ウレイドペニシリン</a>・クラスのひとつ<sup id="cite_ref-1" class="reference"><a href="#cite_note-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup>。日本での製品名は「ペントシリン」(<a href="/wiki/%E5%AF%8C%E5%B1%B1%E5%8C%96%E5%AD%A6%E5%B7%A5%E6%A5%AD" title="富山化学工業">富山化学工業</a>が開発・富士フイルム富山化学が製造販売)。ピペラシリンとその他のウレイドペニシリンの化学構造は、極性側鎖を持つ。これは<a href="/wiki/%E3%82%B0%E3%83%A9%E3%83%A0%E9%99%B0%E6%80%A7%E8%8F%8C" title="グラム陰性菌">グラム陰性菌</a>に対して高い浸透性と、グラム陰性菌βラクタマーゼによる分解感受性を低下させる。これらの性質は病院での重要な病原菌である<a href="/wiki/%E7%B7%91%E8%86%BF%E8%8F%8C" title="緑膿菌">緑膿菌</a>に対する活性を持つ。このような性質から、ピペラシリンはときに「抗緑膿菌ペニシリン」と呼ばれる。 </p><p>ピペラシリンは単独で用いられる時には <a href="/wiki/%E9%BB%84%E8%89%B2%E3%83%96%E3%83%89%E3%82%A6%E7%90%83%E8%8F%8C" title="黄色ブドウ球菌">黄色ブドウ球菌</a>のなどの<a href="/wiki/%E3%82%B0%E3%83%A9%E3%83%A0%E9%99%BD%E6%80%A7%E8%8F%8C" title="グラム陽性菌">グラム陽性菌</a>への強い活性を持たない。またβ-ラクタム構造は細菌の <a href="/wiki/%CE%92-%E3%83%A9%E3%82%AF%E3%82%BF%E3%83%9E%E3%83%BC%E3%82%BC" title="Β-ラクタマーゼ">β-ラクタマーゼ</a>で加水分解される。<sup id="cite_ref-2" class="reference"><a href="#cite_note-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> </p><p>ピペラシリンは最も一般的には β-ラクタマーゼ阻害剤である<a href="/wiki/%E3%82%BF%E3%82%BE%E3%83%90%E3%82%AF%E3%82%BF%E3%83%A0" title="タゾバクタム">タゾバクタム</a>(Piperacillin/Tazobactam)(製品名「ゾシン」「タゾシン」「Zosyn」または「Tazocin」)とピペラシリンとの組み合わせで用いられる。タゾバクタムは多くのβラクタマーゼを阻害する。<a href="/wiki/%E3%83%94%E3%83%9A%E3%83%A9%E3%82%B7%E3%83%AA%E3%83%B3%E3%83%BB%E3%82%BF%E3%82%BE%E3%83%90%E3%82%AF%E3%82%BF%E3%83%A0" title="ピペラシリン・タゾバクタム">ピペラシリン・タゾバクタム</a>の合剤は <a href="/wiki/%E3%83%A1%E3%83%81%E3%82%B7%E3%83%AA%E3%83%B3%E8%80%90%E6%80%A7%E9%BB%84%E8%89%B2%E3%83%96%E3%83%89%E3%82%A6%E7%90%83%E8%8F%8C" title="メチシリン耐性黄色ブドウ球菌">MRSA</a>に対しては投与されない。他のペニシリン／βラクタム系抗生物質同様、MRSAのペニシリン結合蛋白に結合しないからである。<sup id="cite_ref-3" class="reference"><a href="#cite_note-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup> </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="薬理"><span id=".E8.96.AC.E7.90.86"></span>薬理</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E3%83%94%E3%83%9A%E3%83%A9%E3%82%B7%E3%83%AA%E3%83%B3&action=edit&section=1" title="節を編集: 薬理"><span>編集</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li>抗菌作用<sup id="cite_ref-4" class="reference"><a href="#cite_note-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup></li></ul> <dl><dd>ピペラシリンは緑膿菌を含むグラム陰性菌、腸球菌属を含むグラム陽性菌、また<a href="/wiki/%E3%83%90%E3%82%AF%E3%83%86%E3%83%AD%E3%82%A4%E3%83%87%E3%82%B9" class="mw-redirect" title="バクテロイデス">バクテロイデス</a>属を含む嫌気性菌に対し効果があり、幅広い抗菌スペクトルを有する。グラム陰性の<a href="/wiki/%E3%82%A4%E3%83%B3%E3%83%95%E3%83%AB%E3%82%A8%E3%83%B3%E3%82%B6%E8%8F%8C" title="インフルエンザ菌">インフルエンザ菌</a>に対するMIC90は2μg／mL、グラム陽性の<a href="/wiki/%E8%82%BA%E7%82%8E%E7%90%83%E8%8F%8C" class="mw-redirect" title="肺炎球菌">肺炎球菌</a>に対するMIC90は2μg／mLであり、セフェム系の<a href="/wiki/%E3%83%95%E3%83%AD%E3%83%A2%E3%82%AD%E3%82%BB%E3%83%95" title="フロモキセフ">フロモキセフ</a>より優れた抗菌力を示した(in vitro)。</dd></dl> <ul><li>作用機序<sup id="cite_ref-5" class="reference"><a href="#cite_note-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup></li></ul> <dl><dd>細菌の<a href="/wiki/%E7%B4%B0%E8%83%9E%E5%A3%81" title="細胞壁">細胞壁</a>合成を阻害し、殺菌作用を有する。</dd></dl> <div class="mw-heading mw-heading2"><h2 id="適応"><span id=".E9.81.A9.E5.BF.9C"></span>適応</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E3%83%94%E3%83%9A%E3%83%A9%E3%82%B7%E3%83%AA%E3%83%B3&action=edit&section=2" title="節を編集: 適応"><span>編集</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>ピペラシリンは、βラクタマーゼ阻害剤タゾバクタムとの合剤で、重症の院内感染症でしばしば用いられる。この合剤は、米国の連邦政府以外の病院で最も広く使用されている薬物療法の一つであり、低価格の<a href="/wiki/%E3%82%B8%E3%82%A7%E3%83%8D%E3%83%AA%E3%83%83%E3%82%AF%E5%8C%BB%E8%96%AC%E5%93%81" class="mw-redirect" title="ジェネリック医薬品">ジェネリック医薬品</a>であるにもかかわらず、3億8800万ドルの支出を占める<sup id="cite_ref-6" class="reference"><a href="#cite_note-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup> </p><p>ピペラシリン・タゾバクタムは、<a href="/wiki/%E5%A4%9A%E5%89%A4%E8%80%90%E6%80%A7%E8%8F%8C" class="mw-redirect" title="多剤耐性菌">多剤耐性菌</a>の<a href="/wiki/%E9%99%A2%E5%86%85%E6%84%9F%E6%9F%93" title="院内感染">院内感染</a>が疑われる<a href="/wiki/%E9%99%A2%E5%86%85%E8%82%BA%E7%82%8E" title="院内肺炎">院内肺炎</a>の治療において、3剤併用レジメンの一部として推奨されている<sup id="cite_ref-7" class="reference"><a href="#cite_note-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup>。またこれは嫌気性グラム陰性桿菌の感染症に対する推奨される抗菌剤の一つである<sup id="cite_ref-8" class="reference"><a href="#cite_note-8"><span class="cite-bracket">[</span>8<span class="cite-bracket">]</span></a></sup>。 </p><p>ピペラシリン・タゾバクタムは<a href="/wiki/%E3%82%A2%E3%83%A1%E3%83%AA%E3%82%AB%E5%9B%BD%E7%AB%8B%E8%A1%9B%E7%94%9F%E7%A0%94%E7%A9%B6%E6%89%80" title="アメリカ国立衛生研究所">アメリカ国立衛生研究所</a>により、<a href="/wiki/%E5%A5%BD%E4%B8%AD%E7%90%83" title="好中球">好中球</a>減少に伴う<a href="/wiki/%E6%95%97%E8%A1%80%E7%97%87" title="敗血症">敗血症</a>の<a href="/wiki/%E3%82%A8%E3%83%B3%E3%83%94%E3%83%AA%E3%83%83%E3%82%AF" class="mw-redirect" title="エンピリック">エンピリック</a>治療に推奨されている<sup id="cite_ref-9" class="reference"><a href="#cite_note-9"><span class="cite-bracket">[</span>9<span class="cite-bracket">]</span></a></sup>。 </p> <div class="mw-heading mw-heading3"><h3 id="適応菌種"><span id=".E9.81.A9.E5.BF.9C.E8.8F.8C.E7.A8.AE"></span>適応菌種</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E3%83%94%E3%83%9A%E3%83%A9%E3%82%B7%E3%83%AA%E3%83%B3&action=edit&section=3" title="節を編集: 適応菌種"><span>編集</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li>ピペラシリンに感性の<a href="/wiki/%E3%83%96%E3%83%89%E3%82%A6%E7%90%83%E8%8F%8C" title="ブドウ球菌">ブドウ球菌</a>属、レンサ球菌属、<a href="/wiki/%E8%82%BA%E7%82%8E%E7%90%83%E8%8F%8C" class="mw-redirect" title="肺炎球菌">肺炎球菌</a>、腸球菌属、大腸菌、シトロバクター属、<a href="/wiki/%E3%82%AF%E3%83%AC%E3%83%96%E3%82%B7%E3%82%A8%E3%83%A9%E3%83%BB%E3%83%8B%E3%83%A5%E3%83%BC%E3%83%A2%E3%83%8B%E3%82%A8" title="クレブシエラ・ニューモニエ">肺炎桿菌</a>、エンテロバクター属、セラチア属、プロテウス属、モルガネラ・モルガニー、プロビデンシア属、<a href="/wiki/%E3%82%A4%E3%83%B3%E3%83%95%E3%83%AB%E3%82%A8%E3%83%B3%E3%82%B6%E8%8F%8C" title="インフルエンザ菌">インフルエンザ菌</a>、緑膿菌、バクテロイデス属、プレボテラ属（プレボテラ・ビビアを除く）</li></ul> <div class="mw-heading mw-heading3"><h3 id="適応症"><span id=".E9.81.A9.E5.BF.9C.E7.97.87"></span>適応症</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E3%83%94%E3%83%9A%E3%83%A9%E3%82%B7%E3%83%AA%E3%83%B3&action=edit&section=4" title="節を編集: 適応症"><span>編集</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a href="/wiki/%E6%95%97%E8%A1%80%E7%97%87" title="敗血症">敗血症</a>、急性<a href="/wiki/%E6%B0%97%E7%AE%A1%E6%94%AF%E7%82%8E" title="気管支炎">気管支炎</a>、<a href="/wiki/%E8%82%BA%E7%82%8E" title="肺炎">肺炎</a>、肺膿瘍、膿胸、慢性呼吸器病変の二次感染、<a href="/wiki/%E8%86%80%E8%83%B1%E7%82%8E" title="膀胱炎">膀胱炎</a>、腎盂腎炎、胆のう炎、胆管炎、バルトリン腺炎、子宮内感染、子宮付属器炎、子宮旁結合織炎、化膿性髄膜炎</li></ul> <div class="mw-heading mw-heading2"><h2 id="副作用"><span id=".E5.89.AF.E4.BD.9C.E7.94.A8"></span>副作用</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E3%83%94%E3%83%9A%E3%83%A9%E3%82%B7%E3%83%AA%E3%83%B3&action=edit&section=5" title="節を編集: 副作用"><span>編集</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>ピペラシリン・タゾバクタム合剤の最も一般的な副作用は、<a href="/wiki/%E4%B8%8B%E7%97%A2" title="下痢">下痢</a>、<a href="/wiki/%E4%BE%BF%E7%A7%98" title="便秘">便秘</a>、吐き気、<a href="/wiki/%E9%A0%AD%E7%97%9B" title="頭痛">頭痛</a>や<a href="/wiki/%E4%B8%8D%E7%9C%A0" class="mw-redirect" title="不眠">不眠</a>である。あまりみられない副作用には、<a href="/wiki/%E3%82%A2%E3%83%8A%E3%83%95%E3%82%A3%E3%83%A9%E3%82%AD%E3%82%B7%E3%83%BC" title="アナフィラキシー">アナフィラキシー</a>、<a href="/wiki/Stevens-Johnson%E7%97%87%E5%80%99%E7%BE%A4" class="mw-redirect" title="Stevens-Johnson症候群">Stevens-Johnson症候群</a>、 <a href="/wiki/%E3%82%AF%E3%83%AD%E3%82%B9%E3%83%88%E3%83%AA%E3%82%B8%E3%82%A6%E3%83%A0%E3%83%BB%E3%83%87%E3%82%A3%E3%83%95%E3%82%A3%E3%82%B7%E3%83%AB%E8%85%B8%E7%82%8E" title="クロストリジウム・ディフィシル腸炎"><i>Clostridium difficile</i> 関連下痢</a>等がある<sup id="cite_ref-10" class="reference"><a href="#cite_note-10"><span class="cite-bracket">[</span>10<span class="cite-bracket">]</span></a></sup>。 </p> <div class="mw-heading mw-heading2"><h2 id="投与"><span id=".E6.8A.95.E4.B8.8E"></span>投与</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E3%83%94%E3%83%9A%E3%83%A9%E3%82%B7%E3%83%AA%E3%83%B3&action=edit&section=6" title="節を編集: 投与"><span>編集</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>ピペラシリンは経口投与では吸収されず、 <a href="/wiki/%E7%82%B9%E6%BB%B4%E9%9D%99%E8%84%88%E6%B3%A8%E5%B0%84" class="mw-redirect" title="点滴静脈注射">静脈内</a> または <a href="/wiki/%E7%AD%8B%E8%82%89%E5%86%85%E6%B3%A8%E5%B0%84" title="筋肉内注射">筋肉内注射</a>により投与される。持続投与と間欠投与の特徴も検討されている。<sup id="cite_ref-11" class="reference"><a href="#cite_note-11"><span class="cite-bracket">[</span>11<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="脚注"><span id=".E8.84.9A.E6.B3.A8"></span>脚注</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=%E3%83%94%E3%83%9A%E3%83%A9%E3%82%B7%E3%83%AA%E3%83%B3&action=edit&section=7" title="節を編集: 脚注"><span>編集</span></a><span 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(2006). <a href="/wiki/Doi_(%E8%AD%98%E5%88%A5%E5%AD%90)" class="mw-redirect" title="Doi (識別子)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1128%2FAAC.00329-06">10.1128/AAC.00329-06</a>. <a href="/wiki/PMC_(%E8%AD%98%E5%88%A5%E5%AD%90)" class="mw-redirect" title="PMC (識別子)">PMC</a> <a rel="nofollow" class="external text" href="https://pmc.ncbi.nlm.nih.gov/articles/PMC1635208/">1635208</a>. <link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r101121245"><a href="/wiki/PMID_(%E8%AD%98%E5%88%A5%E5%AD%90)" class="mw-redirect" title="PMID (識別子)">PMID</a> <a rel="nofollow" class="external text" href="//pubmed.ncbi.nlm.nih.gov/16940077/">16940077</a><span style="display:none;">. <a rel="nofollow" class="external free" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635208/">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635208/</a></span>.</cite><span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Randomized%2C+open-label%2C+comparative+study+of+piperacillin-tazobactam+administered+by+continuous+infusion+versus+intermittent+infusion+for+treatment+of+hospitalized+patients+with+complicated+intra-abdominal+infection&rft.jtitle=Antimicrob+Agents+Chemother&rft.date=2006&rft.volume=50&rft.issue=11&rft.pages=3556%E2%80%9361&rft_id=info:doi/10.1128%2FAAC.00329-06&rft_id=info:pmc/1635208&rft_id=info:pmid/16940077&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC1635208%2F&rfr_id=info:sid/ja.wikipedia.org:%E3%83%94%E3%83%9A%E3%83%A9%E3%82%B7%E3%83%AA%E3%83%B3"><span style="display: none;"> </span></span></span> </li> </ol></div>    </div><noscript><img src="https://login.wikimedia.org/wiki/Special:CentralAutoLogin/start?type=1x1" alt="" width="1" height="1" style="border: none; position: absolute;"></noscript> <div class="printfooter" data-nosnippet="">「<a dir="ltr" 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