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ProteinSimple Maurice - CE-SDS & icIEF Instrument | Bio-Techne
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<li> Products </li> <li> <a href="/search?keywords=Imaged%20Capillary%20Electrophoresis%20%28iCE%29&category_attr=Imaged%20Capillary%20Electrophoresis%20%28iCE%29">Imaged Capillary Electrophoresis (iCE)</a> </li> <li> Maurice (090-000) </li> </ol> </nav> </div> </div> </div> </div> <div class="row"> <div class="col-md-12"> <main> <section class="section"> <div> <div id="block-bio-techne-global-content" class="system_main_block"> <div class="top_region"><div class="o___product-summary mb-3 border-bottom"><div id="pp-page-title-brand-wrapper"> <div id="header-subheader" data-section="section-base--header-subheader"> <div class="row" id="pp-page-title-brand-wrapper"> <div class="col-lg-9 col-md-12"> <h1 class="font-weight-bold"> Maurice CE-SDS and icIEF Instrument </h1> <h2 class="font-weight-normal h4"> ProteinSimple, part of Bio-Techne | Catalog # <span id="product-code" class="font-weight-bold">090-000</span> </h2> <div id="pp-reviews-citations-row"> <div id="header_left" class="row"> <div class="col-auto d-flex align-self-center"> <div> <a href="#product-documents" class="arena_link product-documents" rel="nofollow">Product Documents</a> </div> </div> </div> </div> <div id="new_version_available"> </div> </div> <div class="col-lg-3 col-md-12"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/logos/bio-techne-proteinsimple.svg" alt="ProteinSimple, part of Bio-Techne" class="d-flex h-100 w-100"> </div> </div> </div> </div> </div> <div class="row mb-4"><div class="col-xl-3 order-xl-first" id="image_wrapper"><div id="images_summary"><article class="product-data-wrapper"> <div class="image-slider-container"> <div class="product-image-lightbox" data-brand="proteinsimple"> <div class="text-center border rounded p-2 item d-flex align-items-center justify-content-center bg-white active"> <img src="https://resources.rndsystems.com/images/datasheets/090-000_maurice-1372020131552.png" data-src=https://resources.rndsystems.com/images/datasheets/090-000_maurice-1372020131552.png data-srcset=https://resources.rndsystems.com/images/datasheets/090-000_maurice-1372020131552.png alt="Maurice - Your workhorse station for purity, identity and heterogeneity analysis" title="Maurice - CE-SDS & icIEF iCE Platform | ProteinSimple" data-caption=" Maurice from ProteinSimple, a Bio-Techne brand, innovates capillary electrophoresis technology to automate protein profiling by size or charge. Get cIEF & CE-SDS data in minutes." data-badges="" data-application="N/A" data-header="Maurice, Catalog # 090-000" width="250" height="250" fetchpriority=high as=image class="search_result_thumbnail_image" /> <div class="slider-open"> <div class="count-container text-center px-2 py-2 border-top border-left rounded-left"> <span class="icon-icon-image-camera-plus align-middle"></span> <span class="image-count-text align-middle">(5)</span> </div> </div> </div> <i data-src="https://resources.rndsystems.com/images/datasheets/090-000_ice-capillary-electropheresis-maurice-fusion-protein-and-adc-graphs.png" data-alt="My molecule has complicated charge profiles that are difficult to resolve" title="My molecule has complicated charge profiles that are difficult to resolve" data-caption="Maurice affords high-resolution characterization of charge variants by preserving our proprietary imaged capillary isoelectric focusing (icIEF) technology, which has been the go-to method for measuring charge heterogeneity. The whole-column detection eliminates the post-focusing mobilization step needed with traditional cIEF, and can resolve your most challenging molecules including fusion proteins and hydrophobic ADCs." data-badges="" data-application="" data-header="Maurice, Catalog # 090-000" data-width="250" data-height="250" class="none"></i> <i data-src="https://resources.rndsystems.com/images/datasheets/090-000_ice-capillary-electropheresis-maurice-fig-2a.png" data-alt="My current method is not reproducible and error-prone" title="My current method is not reproducible and error-prone" data-caption="Maurice employs a prequalified, ready-to-use cartridge design which fully automates column conditioning and clean up. No laborious capillary assembly or maintenance is required. The on-board sample mixing feature further enhances the ease-of-use, and reduces operator-dependent variability commonly encountered with other systems." data-badges="" data-application="" data-header="Maurice, Catalog # 090-000" data-width="250" data-height="250" class="none"></i> <i data-src="https://resources.rndsystems.com/images/datasheets/090-000_ice-capillary-electropheresis-maurice-fig-1a.png" data-alt="I have many samples and my schedule is tight" title="I have many samples and my schedule is tight" data-caption="Maurice produces pI and charge heterogeneity data in less than 10 minutes, and size-based CE-SDS data in 35 minutes. The fast separation time, flexible workflow and high reproducibility makes Maurice a true lab workhorse. In one day you can complete your method development, or analyze 48 to 100 samples in one batch. The icing? You can develop platform methods and use them for multiple molecules too." data-badges="" data-application="" data-header="Maurice, Catalog # 090-000" data-width="250" data-height="250" class="none"></i> <i data-src="https://resources.rndsystems.com/images/datasheets/090-000_ice-capillary-electropheresis-maurice_fig_3.png" data-alt="My sample is limited and they tend to aggregate at high concentration" title="My sample is limited and they tend to aggregate at high concentration" data-caption="Maurice's native fluorescence detection for cIEF provides 3-5X higher sensitivity than UV absorption, which means you can now measure sample at concentration as low as 0.7 µg/ml. And because proteins tend to aggregate less at lower concentrations you can reduce or even eliminate urea completely in some of your methods. Baselines are also significantly cleaner and less sensitive to ampholyte interference, giving you more options when optimizing your pH gradient." data-badges="" data-application="" data-header="Maurice, Catalog # 090-000" data-width="250" data-height="250" class="none"></i> </div> </div> </article> </div> </div> <div class="col-xl-9 order-xl-first" id="key_benefits_buttoon_wrapper"> <h3>Your workhorse station for purity, identity and heterogeneity analysis</h3> <article class="product-data-wrapper "> Maurice innovates the conventional capillary electrophoresis technology to automate your protein profiling either by size or charge. Need cIEF and CE-SDS data for your mAbs, ADCs, vaccines or virus-like particles? Maurice does it all. Just pop in one of the preassembled cartridges, drop in your sample vials or a 96-well plate, and hit start. You'll complete your method development in a day and get high-resolution, reproducible data in minutes. Get compliant data with either Compass for iCE or Waters Empower software. </article> <div id="pp-orderblock-buttons"><div class="float-right mt-3"> <a class="btn a___button-primary m-1 mt-3 col-xs-4" href="/p/instruments/imaged-capillary-electrophoresis-ice/request-quote?productName=Maurice&catalogNumber=090-000" target="_self"> Request Pricing </a> </div> </div> </div> <div class="col-xl-3" id="product_ads_wrapper"><article class="product-data-wrapper"> </article> </div> </div> </div> <div><div id="instrument_meet_section"><div id="instrument_meet_section" class="top_region"> <div class="row"> <div class="col-md-6"> <h3 class="mb-2">Purity, identity and heterogeneity</h3> Still spending weeks or months on method development for your biologics? This new advanced CE platform lets you easily switch between cIEF and CE-SDS applications and develop platform methods within a day. In this short video, the people behind the gold-standard iCE technology highlight the key benefits of the new platform for CE analysts. Find out how Maurice makes CE easy with his streamlined workflow and delivers identity, purity and heterogeneity data on your biologics fast. </div> <div class="col-md-6" > <div class="embed-responsive embed-responsive-16by9"> <iframe width="560" height="315" src="https://www.youtube.com/embed/UxfqnBD4VLA" allow="accelerometer; encrypted-media; gyroscope; picture-in-picture" allowfullscreen> </iframe> </div> </div> </div> </div> </div> </div> <div><div id="instrument_additional_section"> <div class="paragraph paragraph--type--product-page-content paragraph--view-mode--full"> </div> </div> </div> <div class="tab-content"><div id="about-data-tab-tab"></div> <ul class="nav nav-tabs nav-fill " id="productTab" role="tablist"> <li class="nav-item"> <a class="nav-link active" id="about-maurice-tab-tab" href="#about-maurice-tab" data-toggle="tab" role="tab" aria-controls="region-4171591922717" aria-selected="true" >About Maurice</a> </li> <li class="nav-item"> <a class="nav-link" id="citations-tab-tab" href="#citations-tab" data-toggle="tab" role="tab" aria-controls="region-8961620056042" aria-selected="false" >Citations / Testimonials (4)</a> </li> </ul> <div class="tab-content rounded-bottom border-left border-right border-bottom mb-3" id="ProductTabContent"><div class="tab-pane fade show active mx-4" id="about-maurice-tab" data-tab-label="About Maurice" role="tabpanel" aria-labelledby="about-maurice-tab-tab"><div class="product_details_anchors"><div class="product-pages-anchors nav mx-0 pt-4 pb-2 m___nav-anchors d-none d-lg-flex"><li id="how-can-maurice-help-you_li" class="nav-item m-0"> <a class="nav-link py-0 px-2 jump-anchor active" href="#how-can-maurice-help-you" id="how-can-maurice-help-you_li" >How Can Maurice Help You?</a> </li> <li id="how-does-maurice-work_li" class="nav-item m-0"> <a class="nav-link py-0 px-2 jump-anchor" href="#how-does-maurice-work" id="how-does-maurice-work_li" >How Does Maurice Work?</a> </li> <li id="applications_li" class="nav-item m-0"> <a class="nav-link py-0 px-2 jump-anchor" href="#applications" id="applications_li" >Applications</a> </li> <li id="products-compatible-with-maurice_li" class="nav-item m-0"> <a class="nav-link py-0 px-2 jump-anchor" href="#products-compatible-with-maurice" id="products-compatible-with-maurice_li" >Products Compatible with Maurice</a> </li> <li id="specifications_li" class="nav-item m-0"> <a class="nav-link py-0 px-2 jump-anchor" href="#specifications" id="specifications_li" >Specifications</a> </li> <li id="product-documents_li" class="nav-item m-0"> <a class="nav-link py-0 px-2 product-documents" href="#product-documents" id="product-documents_li" >Product Documents</a> </li> </div> <div id="how-can-maurice-help-you" class="nav-link px-0" data-anchor-label="How Can Maurice Help You?"><table class="product-data-wrapper tablesaw tablesaw-stack table" id="data_image_table_wrapper"><h3>How Can Maurice Help You?</h3><article class="product-data-wrapper"> <tr class="row m___product-data-examples"> <td class="border-0"> <div class="image-slider-container"> <div class="product-image-lightbox" data-brand=""> <div class="text-center border rounded p-2 item d-flex align-items-center justify-content-center bg-white active"> <img src="data:image/png;base64,R0lGODlhAQABAAD/ACwAAAAAAQABAAACADs=" data-src="https://resources.rndsystems.com/images/datasheets/090-000_ice-capillary-electropheresis-maurice-fusion-protein-and-adc-graphs.png" data-srcset="https://resources.rndsystems.com/images/datasheets/090-000_ice-capillary-electropheresis-maurice-fusion-protein-and-adc-graphs.png" alt="My molecule has complicated charge profiles that are difficult to resolve" title="My molecule has complicated charge profiles that are difficult to resolve" data-caption="Maurice affords high-resolution characterization of charge variants by preserving our proprietary imaged capillary isoelectric focusing (icIEF) technology, which has been the go-to method for measuring charge heterogeneity. The whole-column detection eliminates the post-focusing mobilization step needed with traditional cIEF, and can resolve your most challenging molecules including fusion proteins and hydrophobic ADCs." data-badges="" data-application="" data-header="Maurice, Catalog # 090-000" width="250" height="250" class="search_result_thumbnail_image lazy" /> <div class="slider-open"> <div class="count-container text-center px-2 py-2 border-top border-left rounded-left"> <span class="icon-icon-image-camera-plus align-middle"></span> </div> </div> </div> </div> </div> </td> <td class="w-75 border-0 align-top"> <h4>My molecule has complicated charge profiles that are difficult to resolve</h4> <p> Maurice affords high-resolution characterization of charge variants by preserving our proprietary imaged capillary isoelectric focusing (icIEF) technology, which has been the go-to method for measuring charge heterogeneity. The whole-column detection eliminates the post-focusing mobilization step needed with traditional cIEF, and can resolve your most challenging molecules including fusion proteins and hydrophobic ADCs. </p> </td> </tr> <tr class="row m___product-data-examples"> <td class="border-0"> <div class="image-slider-container"> <div class="product-image-lightbox" data-brand=""> <div class="text-center border rounded p-2 item d-flex align-items-center justify-content-center bg-white active"> <img src="data:image/png;base64,R0lGODlhAQABAAD/ACwAAAAAAQABAAACADs=" data-src="https://resources.rndsystems.com/images/datasheets/090-000_ice-capillary-electropheresis-maurice-fig-2a.png" data-srcset="https://resources.rndsystems.com/images/datasheets/090-000_ice-capillary-electropheresis-maurice-fig-2a.png" alt="My current method is not reproducible and error-prone" title="My current method is not reproducible and error-prone" data-caption="Maurice employs a prequalified, ready-to-use cartridge design which fully automates column conditioning and clean up. No laborious capillary assembly or maintenance is required. The on-board sample mixing feature further enhances the ease-of-use, and reduces operator-dependent variability commonly encountered with other systems." data-badges="" data-application="" data-header="Maurice, Catalog # 090-000" width="250" height="250" class="search_result_thumbnail_image lazy" /> <div class="slider-open"> <div class="count-container text-center px-2 py-2 border-top border-left rounded-left"> <span class="icon-icon-image-camera-plus align-middle"></span> </div> </div> </div> </div> </div> </td> <td class="w-75 border-0 align-top"> <h4>My current method is not reproducible and error-prone</h4> <p> Maurice employs a prequalified, ready-to-use cartridge design which fully automates column conditioning and clean up. No laborious capillary assembly or maintenance is required. The on-board sample mixing feature further enhances the ease-of-use, and reduces operator-dependent variability commonly encountered with other systems. </p> </td> </tr> <tr class="row m___product-data-examples"> <td class="border-0"> <div class="image-slider-container"> <div class="product-image-lightbox" data-brand=""> <div class="text-center border rounded p-2 item d-flex align-items-center justify-content-center bg-white active"> <img src="data:image/png;base64,R0lGODlhAQABAAD/ACwAAAAAAQABAAACADs=" data-src="https://resources.rndsystems.com/images/datasheets/090-000_ice-capillary-electropheresis-maurice-fig-1a.png" data-srcset="https://resources.rndsystems.com/images/datasheets/090-000_ice-capillary-electropheresis-maurice-fig-1a.png" alt="I have many samples and my schedule is tight" title="I have many samples and my schedule is tight" data-caption="Maurice produces pI and charge heterogeneity data in less than 10 minutes, and size-based CE-SDS data in 35 minutes. The fast separation time, flexible workflow and high reproducibility makes Maurice a true lab workhorse. In one day you can complete your method development, or analyze 48 to 100 samples in one batch. The icing? You can develop platform methods and use them for multiple molecules too." data-badges="" data-application="" data-header="Maurice, Catalog # 090-000" width="250" height="250" class="search_result_thumbnail_image lazy" /> <div class="slider-open"> <div class="count-container text-center px-2 py-2 border-top border-left rounded-left"> <span class="icon-icon-image-camera-plus align-middle"></span> </div> </div> </div> </div> </div> </td> <td class="w-75 border-0 align-top"> <h4>I have many samples and my schedule is tight</h4> <p> Maurice produces pI and charge heterogeneity data in less than 10 minutes, and size-based CE-SDS data in 35 minutes. The fast separation time, flexible workflow and high reproducibility makes Maurice a true lab workhorse. In one day you can complete your method development, or analyze 48 to 100 samples in one batch. The icing? You can develop platform methods and use them for multiple molecules too. </p> </td> </tr> <tr class="row m___product-data-examples"> <td class="border-0"> <div class="image-slider-container"> <div class="product-image-lightbox" data-brand=""> <div class="text-center border rounded p-2 item d-flex align-items-center justify-content-center bg-white active"> <img src="data:image/png;base64,R0lGODlhAQABAAD/ACwAAAAAAQABAAACADs=" data-src="https://resources.rndsystems.com/images/datasheets/090-000_ice-capillary-electropheresis-maurice-lp-03-16-17-figure2.png" data-srcset="https://resources.rndsystems.com/images/datasheets/090-000_ice-capillary-electropheresis-maurice-lp-03-16-17-figure2.png" alt="I am concerned about cross-contamination between applications" title="I am concerned about cross-contamination between applications" data-caption="Maurice employs completely separate fluid paths for cIEF and CE-SDS applications. Waste is collected inside the cartridge which removes the concern about cross-contamination between experiments. In addition, when dealing with molecules such as ADCs, no more hassle about handling the toxic waste." data-badges="" data-application="" data-header="Maurice, Catalog # 090-000" width="250" height="250" class="search_result_thumbnail_image lazy" /> <div class="slider-open"> <div class="count-container text-center px-2 py-2 border-top border-left rounded-left"> <span class="icon-icon-image-camera-plus align-middle"></span> </div> </div> </div> </div> </div> </td> <td class="w-75 border-0 align-top"> <h4>I am concerned about cross-contamination between applications</h4> <p> Maurice employs completely separate fluid paths for cIEF and CE-SDS applications. Waste is collected inside the cartridge which removes the concern about cross-contamination between experiments. In addition, when dealing with molecules such as ADCs, no more hassle about handling the toxic waste. </p> </td> </tr> <tr class="row m___product-data-examples"> <td class="border-0"> <div class="image-slider-container"> <div class="product-image-lightbox" data-brand=""> <div class="text-center border rounded p-2 item d-flex align-items-center justify-content-center bg-white active"> <img src="data:image/png;base64,R0lGODlhAQABAAD/ACwAAAAAAQABAAACADs=" data-src="https://resources.rndsystems.com/images/datasheets/090-000_ice-capillary-electropheresis-maurice_fig_3.png" data-srcset="https://resources.rndsystems.com/images/datasheets/090-000_ice-capillary-electropheresis-maurice_fig_3.png" alt="My sample is limited and they tend to aggregate at high concentration" title="My sample is limited and they tend to aggregate at high concentration" data-caption="Maurice's native fluorescence detection for cIEF provides 3-5X higher sensitivity than UV absorption, which means you can now measure sample at concentration as low as 0.7 µg/ml. And because proteins tend to aggregate less at lower concentrations you can reduce or even eliminate urea completely in some of your methods. Baselines are also significantly cleaner and less sensitive to ampholyte interference, giving you more options when optimizing your pH gradient." data-badges="" data-application="" data-header="Maurice, Catalog # 090-000" width="250" height="250" class="search_result_thumbnail_image lazy" /> <div class="slider-open"> <div class="count-container text-center px-2 py-2 border-top border-left rounded-left"> <span class="icon-icon-image-camera-plus align-middle"></span> </div> </div> </div> </div> </div> </td> <td class="w-75 border-0 align-top"> <h4>My sample is limited and they tend to aggregate at high concentration</h4> <p> Maurice's native fluorescence detection for cIEF provides 3-5X higher sensitivity than UV absorption, which means you can now measure sample at concentration as low as 0.7 µg/ml. And because proteins tend to aggregate less at lower concentrations you can reduce or even eliminate urea completely in some of your methods. Baselines are also significantly cleaner and less sensitive to ampholyte interference, giving you more options when optimizing your pH gradient. </p> </td> </tr> <tr class="row m___product-data-examples"> <td class="border-0"> <div class="image-slider-container"> <div class="product-image-lightbox" data-brand=""> <div class="text-center border rounded p-2 item d-flex align-items-center justify-content-center bg-white active"> <img src="data:image/png;base64,R0lGODlhAQABAAD/ACwAAAAAAQABAAACADs=" data-src="https://resources.rndsystems.com/images/datasheets/090-000_ice-capillary-electropheresis-maurice-21cfr.png" data-srcset="https://resources.rndsystems.com/images/datasheets/090-000_ice-capillary-electropheresis-maurice-21cfr.png" alt="I work in a GMP lab and data integrity is key to my compliance requirement" title="I work in a GMP lab and data integrity is key to my compliance requirement" data-caption="Compass for iCE, the software package Maurice uses to acquire, manage and analyze data, has all the tools required for 21 CFR compliance so you'll have no issue analyzing biotherapeutics on Maurice in a regulated environment." data-badges="" data-application="" data-header="Maurice, Catalog # 090-000" width="250" height="250" class="search_result_thumbnail_image lazy" /> <div class="slider-open"> <div class="count-container text-center px-2 py-2 border-top border-left rounded-left"> <span class="icon-icon-image-camera-plus align-middle"></span> </div> </div> </div> </div> </div> </td> <td class="w-75 border-0 align-top"> <h4>I work in a GMP lab and data integrity is key to my compliance requirement</h4> <p> Compass for iCE, the software package Maurice uses to acquire, manage and analyze data, has all the tools required for 21 CFR compliance so you'll have no issue analyzing biotherapeutics on Maurice in a regulated environment. </p> </td> </tr> </article> </table> </div> <div id="how_does_work-anchor" class="nav-link static-anchor p-0" data-anchor-label="How Does Maurice Work?"></div> <div id="applications-anchor" class="nav-link static-anchor p-0" data-anchor-label="Applications"></div> <div id="products_compatible-anchor" class="nav-link static-anchor p-0" data-anchor-label="Products Compatible with Maurice"></div> <div id="specifications-anchor" class="nav-link static-anchor p-0" data-anchor-label="Specifications"></div> <div id="product-datasheet-anchor" class="nav-link static-anchor p-0" data-anchor-label="Product Documents"></div> </div> </div> <div class="tab-pane fade mx-4 py-4" id="citations-tab" data-tab-label="Citations / Testimonials (4)" role="tabpanel" aria-labelledby="citations-tab-tab"><div class="product_details_anchors mb-2"> <div class="nav mx-0 pt-4 pb-2 m___nav-anchors d-none d-lg-flex"> <li class="nav-item m-0"> <a class="nav-link jump-anchor active" href="#citations"> Citations </a> </li> <li class="nav-item m-0"> <a class="nav-link jump-anchor active" href="#testimonials"> Testimonials </a> </li> </div> </div> <div class="mb-4" id="citations_section"> <div class="pp_filter_list border-bottom mb-4 pb-3"> <h2>Citations for Maurice</h2> <p><a href="/resources/instrument-citations?instrument-platform=imaged%20capillary%20electrophoresis%20%28ice%29" rel="nofollow noopener noreferrer" target="_blank">View all citations for the Imaged Capillary Electrophoresis (iCE) platform.</a><br> Please visit our Instrument Citation Database to search our collection of scientific articles that feature our instruments. </p> </div> </div> <div class="testimonials" id="testimonials"><article class="product-data-wrapper"> <div class="pp_filter_list mt-4 pt-4 border-bottom mb-4 pb-3"> <h2>Testimonials from your Peers for Imaged Capillary Electrophoresis (iCE)</h2> <div class="testimonials_showing pp_filters_showing row col-md-12 mb-2"> <span class="less">Showing <span class="testimonials_show_min font-weight-bold">1</span> <span class="font-weight-bold">-</span> <span class="testimonials_show_max font-weight-bold">4</span> of <span class="testimonials_count font-weight-bold">4</span> testimonials </span> <span class="more font-weight-bold">Showing All</span> </div> <article role="article" class="contextual-region"> <div class="testimonial py-4"> <div class="row"> <aside class="col-lg-2 m___testimonial-aside-search text-center"> <article class="contextual-region"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/sara-carillo-headshot-200x200.png" alt="Sara Carillo Headshot" loading="lazy"> </article> </aside> <section class="col-lg-10"> <div class="testimonial__quote"> <p>"Adding fractionation capabilities can really help in simplifying the workflow to assess peak identity, especially if paired with state-of-the-art mass spectrometry techniques. On top of this, the experience of working with the Bio-Techne family has been a pleasure so far and they helped us throughout our first work, beyond the training aspect of the installation."</p> </div> <div class="testimonial-link"> <a href="/resources/testimonials/streamlining-charge-variant-analysis-with-mauriceflex">Streamlining Charge Variant Analysis with MauriceFlex</a> </div> <p class="testimonial__profile mt-3"> <span class="font-weight-bold"> Dr. Sara Carillo, </span> Bioanalytical Research Lead, NIBRT </p> </section> </div> </div> </article> <article role="article" class="contextual-region"> <div class="testimonial py-4"> <div class="row"> <aside class="col-lg-2 m___testimonial-aside-search text-center"> <article class="contextual-region"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/lg-amreen-jonas-mersana-headshot.png" alt="Discover how Amreen Jonas and the team at Mersana Therapeutics are using MauriceFlex to streamline fraction collection." loading="lazy"> </article> </aside> <section class="col-lg-10"> <div class="testimonial__quote"> <p>"Replacing preparative chromatography with MauriceFlex has made the process of fraction collection more efficient."</p> </div> <div class="testimonial-link"> <a href="/resources/literature/fyp-mersana-accelerating-charge-variant-characterization">The MauriceFlex™ System in Action: Accelerating Protein Charge Variant Characterization</a> </div> <p class="testimonial__profile mt-3"> <span class="font-weight-bold"> Amreen Jonas, </span> Principal Associate Scientist, Mersana Therapeutics </p> </section> </div> </div> </article> <article role="article" class="contextual-region"> <div class="testimonial py-4"> <div class="row"> <aside class="col-lg-2 m___testimonial-aside-search text-center"> <article class="contextual-region"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/testimonials/ice-watzig-hermann.png" alt="Dr. Watzig discusses benefits of capillary electrophoresis" loading="lazy"> </article> </aside> <section class="col-lg-10"> <div class="testimonial__quote"> <p>"I think that the data we produced [on Maurice] shows excellent quality, due to the precise and reliable Maurice instrument."</p> </div> <div class="testimonial-link"> <a href="/resources/testimonials/automated-capillary-electrophoresis-technological-renaissance-biopharmaceuticals">Automated Capillary Electrophoresis: A Technological Renaissance at the Heart of Biopharmaceuticals</a> </div> <p class="testimonial__profile mt-3"> <span class="font-weight-bold"> Professor Hermann Wätzig, </span> Technical University of Braunschweig in Germany </p> </section> </div> </div> </article> <article role="article" class="contextual-region"> <div class="testimonial py-4"> <div class="row"> <aside class="col-lg-2 m___testimonial-aside-search text-center"> <article class="contextual-region"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/testimonials/ice-joan-garrison.png" alt="Joan Garrison testimonial for method development with iCE3" loading="lazy"> </article> </aside> <section class="col-lg-10"> <div class="testimonial__quote"> <p>"The short run times and easy sample preparation allowed for method development within a day or two. The versatility of the instrument allows the possibility of offering clients rapid alternatives to traditional ID and charge heterogeneity assays."</p> </div> <div class="testimonial-link"> <a href="/resources/testimonials/joan-garrison-ice-kicks-method-development-into-high-gear">Joan Kicks Her Method Development into High Gear with iCE3</a> </div> <p class="testimonial__profile mt-3"> <span class="font-weight-bold"> Joan Garrison, </span> QC Method Transfer Scientist, Cook Pharmica </p> </section> </div> </div> </article> <span id="more-testimonials" style="display:none"> </span> <div id="testimonial_counts" data-max="4" data-min="5"> <div class="testimonials_showing pp_filters_showing row col-md-12 mb-2"> <span class="less">Showing <span class="testimonials_show_min font-weight-bold">1</span> <span class="font-weight-bold">-</span> <span class="testimonials_show_max font-weight-bold">4</span> of <span class="testimonials_count font-weight-bold">4</span> testimonials </span> <span class="more font-weight-bold">Showing All</span> </div> </div> <div class="text-center"> </div> </div> </article> </div> </div> </div> </div> <div><div id="accordion" class="border mb-4"> <div class="rounded-top bg-white"> <h3 class="m-0 p-3">More Information About Maurice</h3> </div> <div class="vtab-section" data-section="How Does Maurice Work?" id="how-does-maurice-work"> <div class="card-header rounded-top"> <a id="how-does-maurice-work-link" class="collapsed" data-toggle="collapse" data-target="#collapse_region-5781592502255" aria-expanded="false" aria-controls="collapse_region-5781592502255"> <h5 class="mb-0"> How Does Maurice Work? </h5> </a> </div> <div id="collapse_region-5781592502255" class="collapse " aria-labelledby="heading_region-5781592502255" data-parent="#accordion"> <div class="card-body"> <div id="how-does-maurice-work-vtab" data-tab-label="How Does Maurice Work?" role="tabpanel" aria-labelledby="how-does-maurice-work-vtab-tab"><div id="instrument_how_work_content"> <div class="paragraph paragraph--type--product-page-content paragraph--view-mode--full"> </div> </div> </div> </div> </div> </div> <div class="vtab-section" data-section="Applications" id="applications"> <div class="card-header rounded-top"> <a id="applications-link" class="collapsed" data-toggle="collapse" data-target="#collapse_region-4951592502294" aria-expanded="false" aria-controls="collapse_region-4951592502294"> <h5 class="mb-0"> Applications </h5> </a> </div> <div id="collapse_region-4951592502294" class="collapse " aria-labelledby="heading_region-4951592502294" data-parent="#accordion"> <div class="card-body"> <div id="applications-vtab" data-tab-label="Applications" role="tabpanel" aria-labelledby="applications-vtab-tab"><div id="applications_wrapper"> <div class="paragraph paragraph--type--product-page-content paragraph--view-mode--full"> </div> </div> </div> </div> </div> </div> <div class="vtab-section" data-section="Products Compatible with Maurice" id="products-compatible-with-maurice"> <div class="card-header rounded-top"> <a id="products-compatible-with-maurice-link" class="collapsed" data-toggle="collapse" data-target="#collapse_region-7641628092667" aria-expanded="false" aria-controls="collapse_region-7641628092667"> <h5 class="mb-0"> Products Compatible with Maurice </h5> </a> </div> <div id="collapse_region-7641628092667" class="collapse " aria-labelledby="heading_region-7641628092667" data-parent="#accordion"> <div class="card-body"> <div id="products-compatible-with-maurice-vtab" data-tab-label="Products Compatible with Maurice" role="tabpanel" aria-labelledby="products-compatible-with-maurice-vtab-tab"><div id="products_compatible_with_instrument"><article class="product-data-wrapper"> <ul class="compatible_instruments list-unstyled m-0"> <li class="py-2"><a href="/search?keywords=iCE%20CE-SDS%20Kits&sub_category=iCE%20CE-SDS%20Kits&compatible_instrument=Maurice&view=condensed">iCE CE-SDS Kits</a></li> <li class="py-2"><a href="/search?keywords=iCE%20Consumables&sub_category=iCE%20Consumables&compatible_instrument=Maurice&view=condensed">iCE Consumables</a></li> <li class="py-2"><a href="/search?keywords=iCE%20Reagents&sub_category=iCE%20Reagents&compatible_instrument=Maurice&view=condensed">iCE Reagents</a></li> <li class="py-2"><a href="/search?keywords=iCE%20cIEF%20Kits&sub_category=iCE%20cIEF%20Kits&compatible_instrument=Maurice&view=condensed">iCE cIEF Kits</a></li> <li class="py-2"><a href="/search?keywords=imaged%20capillary%20electrophoresis%20%28ice%29&compatible_instrument=Maurice&view=condensed">View All Products Compatible with Maurice</a></li> </ul> </article> </div> </div> </div> </div> </div> <div class="vtab-section" data-section="Specifications" id="specifications"> <div class="card-header rounded-top"> <a id="specifications-link" class="collapsed" data-toggle="collapse" data-target="#collapse_region-9701592502350" aria-expanded="false" aria-controls="collapse_region-9701592502350"> <h5 class="mb-0"> Specifications </h5> </a> </div> <div id="collapse_region-9701592502350" class="collapse " aria-labelledby="heading_region-9701592502350" data-parent="#accordion"> <div class="card-body"> <div id="specifications-vtab" data-tab-label="Specifications" role="tabpanel" aria-labelledby="specifications-vtab-tab"><div id="instrument_specifications"><table class="tablesaw tablesaw-stack app_table my-3 table-bordered" data-tablesaw-mode="stack"> <thead class="ds_table_head bg-light-gray"> <th class="ds_table_head_cell w-25 p-3">Feature</th> <th class="ds_table_head_cell w-25 p-3">cIEF Specification</th> <th class="ds_table_head_cell w-25 p-3">CE-SDS Specificiation</th> </thead> <tbody class="bg-white"> <tr class="ds_table_row"> <td>Minimum Sample Volume</td> <td colspan="1" class="text-left"> 50 µL </td> <td colspan="1" class="text-left"> 50 µL </td> </tr> <tr class="ds_table_row"> <td>Sample Delivery</td> <td colspan="1" class="text-left"> Vacuum </td> <td colspan="1" class="text-left"> Electrokinetic </td> </tr> <tr class="ds_table_row"> <td>Typical Separation Time</td> <td colspan="1" class="text-left"> 6–10 min (molecule-dependent) </td> <td colspan="1" class="text-left"> Reduced IgG: 25 min, Non-reduced IgG: 35 min </td> </tr> <tr class="ds_table_row"> <td>Detection Capability</td> <td colspan="1" class="text-left"> UV Absorbance at 280 nm<br />Fluorescence: Ex 280 nm, Em 320– 450 nm </td> <td colspan="1" class="text-left"> UV Absorbance at 220 nm </td> </tr> <tr class="ds_table_row"> <td>Typical Voltage</td> <td colspan="1" class="text-left"> Pre-focusing: 1500 V, focusing: 3000 V </td> <td colspan="1" class="text-left"> Separation: 5750 V </td> </tr> <tr class="ds_table_row"> <td>Sample Injections per Cartridge</td> <td colspan="1" class="text-left"> 100 guaranteed, 200 maximum </td> <td colspan="1" class="text-left"> 100 guaranteed, 200 maximum for CE-SDS, 500 maximum for CE-SDS PLUS </td> </tr> <tr class="ds_table_row"> <td>Maximum Sample Injections per Batch</td> <td colspan="1" class="text-left"> 100 </td> <td colspan="1" class="text-left"> 48 </td> </tr> <tr class="ds_table_row"> <td>pI/Size Range</td> <td colspan="1" class="text-left"> 2.85–10.45 </td> <td colspan="1" class="text-left"> 10–270 kDa </td> </tr> <tr class="ds_table_row"> <td>pI/Sizing CV</td> <td colspan="1" class="text-left"> 0.01 </td> <td colspan="1" class="text-left"> ≤2% </td> </tr> <tr class="ds_table_row"> <td>CV for Peaks >10% Composition</td> <td colspan="1" class="text-left"> ≤5% (Intra-batch), ≤6% (Inter-batch) </td> <td colspan="1" class="text-left"> N/A </td> </tr> <tr class="ds_table_row"> <td>Relative Migration Time CV</td> <td colspan="1" class="text-left"> N/A </td> <td colspan="1" class="text-left"> <1% for reduced IgG </td> </tr> <tr class="ds_table_row"> <td>pI/Sizing Resolution</td> <td colspan="1" class="text-left"> 0.05 pI units (for wide range 3–10 ampholytes) </td> <td colspan="1" class="text-left"> ≥1.5 for NGHC/HC IgG Standard </td> </tr> <tr class="ds_table_row"> <td>Dynamic Range</td> <td colspan="1" class="text-left"> 2 logs </td> <td colspan="1" class="text-left"> 2 logs </td> </tr> <tr class="ds_table_row"> <td>Linearity</td> <td colspan="1" class="text-left"> >0.995 </td> <td colspan="1" class="text-left"> >0.995 </td> </tr> <tr class="ds_table_row"> <td>Sensitivity (LOD)</td> <td colspan="1" class="text-left"> 0.7 µg/mL (Native fluorescence) 3.0 µg / mL(Absorbance) (Values based on a monoclonal antibody) </td> <td colspan="1" class="text-left"> 0.3 µg/mL (Value based on Internal Standard) </td> </tr> <tr class="ds_table_row"> <td>Sample Tray Options</td> <td colspan="2" class="text-center"> 96-well plates or 48 vials </td> </tr> <tr class="ds_table_row"> <td>Dimensions</td> <td colspan="2" class="text-center"> 44cm H x 42cm W x 61cm D </td> </tr> <tr class="ds_table_row"> <td>Weight</td> <td colspan="2" class="text-center"> 46 kg (100 lb) </td> </tr> </tbody> </table> </div> </div> </div> </div> </div> </div> </div> <div id="product-documents"> <div id="accordion-arena-documents" class="accordion border mb-4"> <div class="rounded-top bg-white"> <h3 class="m-0 p-3">Product Documents for Maurice</h3> </div> <div class="accordion-item vtab-section"> <div class="card-header rounded-top" id="document-heading1"> <a class="collapsed arena-document-title" id="product-documents-link" data-toggle="collapse" data-target="#document-collapse1" aria-expanded="false" aria-controls="document-collapse1"> <h5>Datasheet</h5> </a> </div> <div id="document-collapse1" class="collapse" aria-labelledby="document-heading1" data-parent="#accordion-arena-documents"> <div class="card-body"> <div class="row"> <div class="col-md-6"> <div id="arena-document-95-5004-00"> <a href="/" class="arena_link download_arena_document" data-category_id="21" data-document_id="95-5004-00" data-document_type="datasheet" target="_blank" rel="nofollow">Download 95-5004-00 Maurice datasheet revF DIGITAL</a> </div> </div> <div class="col-md-6 datasheet-pdf-result"></div> </div> </div> </div> </div> <div class="accordion-item vtab-section"> <div class="card-header rounded-top" id="document-heading2"> <a class="collapsed arena-document-title" data-toggle="collapse" data-target="#document-collapse2" aria-expanded="false" aria-controls="document-collapse2"> <h5>Protocols & Manuals</h5> </a> </div> <div id="document-collapse2" class="collapse" aria-labelledby="document-heading2" data-parent="#accordion-arena-documents"> <div class="card-body"> <div class="row"> <div class="col-md-6"> <div id="arena-document-046-295"> <a href="/" class="arena_link download_arena_document" data-category_id="21" data-document_id="046-295" data-document_type="user-manual" target="_blank" rel="nofollow">Download 046-295 revE Maurice User Guide</a> </div> </div> <div class="col-md-6 datasheet-pdf-result"></div> </div> <div class="row"> <div class="col-md-6"> <div id="arena-document-046-296"> <a href="/" class="arena_link download_arena_document" data-category_id="21" data-document_id="046-296" data-document_type="user-manual" target="_blank" rel="nofollow">Download 046-296 RevD Maurice cIEF Method Development Guide web</a> </div> </div> <div class="col-md-6 datasheet-pdf-result"></div> </div> <div class="row"> <div class="col-md-6"> <div id="arena-document-046-297"> <a href="/" class="arena_link download_arena_document" data-category_id="21" data-document_id="046-297" data-document_type="user-manual" target="_blank" rel="nofollow">Download 046-297 Maurice CE-SDS Application Guide RevH DIGITAL</a> </div> </div> <div class="col-md-6 datasheet-pdf-result"></div> </div> <div class="row"> <div class="col-md-6"> <div id="arena-document-pl2-0022"> <a href="/" class="arena_link download_arena_document" data-category_id="21" data-document_id="pl2-0022" data-document_type="user-manual" target="_blank" rel="nofollow">Download PL2-0022 RevB Maurice Chromeleon User Guide</a> </div> </div> <div class="col-md-6 datasheet-pdf-result"></div> </div> </div> </div> </div> </div> </div> <div id="product-page-details" data-time-Total="0" data-time-ToCompile="0" data-time-ToBuild="0" data-time-Datapoints="0" data-time-Template="0" data-time-Post-EPCC="0" data-time-EPCC="0" data-renderTime="Tuesday 26th of November 2024 07:17:05 PM" data-template="instrument"></div> </div> </div> </section> </main> </div> </div> </div><!-- end main --> <div id="brandsbar-footer" class="bg-bt-primary"> <div class="container-wide container-fluid text-white"> <div class="row py-5"> <div class="footer-logo col-xl-3 col-lg-auto d-flex"> <img class="brand-bar-footer-logo" src="/themes/custom/bio_techne_global/logo.svg" alt="Bio-techne logo"> </div> <div class="col-xl-9 col-lg-auto"> <p class="ml-xl-4 bt-px_groteskbold footer-tagline">Global Developer, Manufacturer, and Supplier of High-Quality Reagents, Analytical Instruments, and Precision Diagnostics.</p> </div> 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