Research and Development

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class="field-basiccontentrichtext"><p>We are in a new era of medicine where breakthrough science is transforming care and our approach to treating patients. Robust investment in research and development (R&D) by biopharmaceutical companies is resulting in advances and discoveries unlike anything we’ve seen before. The application of genomics to develop personalized medicines is enabling physicians to tailor treatments to the unique needs of the patient, and immunotherapies are harnessing patients’ own immune systems to fight off various conditions, including cancer and rare diseases.</p> <p> Over the last decade, PhRMA member companies have invested more than $800 billion in the search for new treatments and cures. While these investments continue to build upon previous medical advances, they are just beginning to yield results on the latest breakthroughs, opening the door to entirely new ways to tackle some of the most complex and difficult to treat diseases of our time. </p> <p>America’s biopharmaceutical sector is the most R&D-intensive industry in the U.S. economy. In fact, the biopharmaceutical industry invests on average six times more in R&D as a percentage of sales than all other manufacturing industries. </p> <p>The progress we see today is revolutionizing how we diagnose, treat and cure disease, saving patients’ lives and improving quality of life across a broad range of chronic and rare conditions. In this new era of medicine, many diseases previously regarded as deadly are now manageable and potentially curable. Today, there are more than 8,000 medicines in clinical development around the world. The future has never been brighter as researchers explore new frontiers that just a few years ago may have been regarded as science fiction, but now transform patients’ lives.</p></div></div><div class="col-sm-12 col-md-5 col-lg-4"> <div class="component phrma-content-promo feature-item side-bar"> <div class="component-content"> <a title="Industry Profile 2022" href="/resource-center/Topics/Research-and-Development/Industry-Profile-2022"><div><div class="feature-image-container"><img src="/-/media/Project/PhRMA/PhRMA-Org/PhRMA-Refresh/Industry-Profile-2022/Teaser-Images/2022ProfileCover_635.jpg?w=403&hash=EBBD044FAB9C74F741D774E2B7414BCB" alt="Teaser image for 2022 Industry Profile Report" sizes="(max-width: 767px) 707px, (max-width: 991px) 451px, 403px" srcset="/-/media/Project/PhRMA/PhRMA-Org/PhRMA-Refresh/Industry-Profile-2022/Teaser-Images/2022ProfileCover_635.jpg?w=707&hash=925C149BE9B94769E134026C3B29DAF6 707w,/-/media/Project/PhRMA/PhRMA-Org/PhRMA-Refresh/Industry-Profile-2022/Teaser-Images/2022ProfileCover_635.jpg?w=+451&hash=26F219542ED99CB53A86A1B98EDB51D2 451w,/-/media/Project/PhRMA/PhRMA-Org/PhRMA-Refresh/Industry-Profile-2022/Teaser-Images/2022ProfileCover_635.jpg?w=+403&hash=7B698E34C34A043EB34E476B0E06222F 403w"></img></div><div class="feature-content-area bg-sky-blue-l10-clear"><div class="rf-btn-link"><span class="pr-2 field-markup"><i class="icon-paragraph-left"></i><p class="d-none">-</p></span><span class="text-uppercase neusa-next-medium field-title"></span></div><p class="feature-title text-gray-5 field-contenttitle">Industry Profile 2022</p></div></div></a> </div> </div> <div class="component phrma-content-promo feature-item side-bar"> <div class="component-content"> <a title="The Biopharmaceutical Research Ecosystem Five Things You Need to Know" href="/Coronavirus/The-Biopharmaceutical-Research-Ecosystem-Five-Things-You-Need-to-Know"><div><div class="feature-image-container"><img src="/-/media/Project/PhRMA/PhRMA-Org/PhRMA-Org/A---C/The-Biopharmaceutical-Ecosystem_1000x635.jpg?w=403&hash=3455E32CB5A5F0EFF79429FCF96963FE" alt="A teaser image of the first page of a recent PhRMA report, reading "The Biopharmaceutical Research Ecosystem—Five Things You Need to Know"" sizes="(max-width: 767px) 707px, (max-width: 991px) 451px, 403px" srcset="/-/media/Project/PhRMA/PhRMA-Org/PhRMA-Org/A---C/The-Biopharmaceutical-Ecosystem_1000x635.jpg?w=707&hash=08448EF506A16528467A6D1F0263F051 707w,/-/media/Project/PhRMA/PhRMA-Org/PhRMA-Org/A---C/The-Biopharmaceutical-Ecosystem_1000x635.jpg?w=+451&hash=F4630C3768B9215CAB0AF153A072533D 451w,/-/media/Project/PhRMA/PhRMA-Org/PhRMA-Org/A---C/The-Biopharmaceutical-Ecosystem_1000x635.jpg?w=+403&hash=FCF8C44BA682123AC60A7D00212BA571 403w"></img></div><div class="feature-content-area bg-sky-blue-l10-clear"><div class="rf-btn-link"><span class="pr-2 field-markup"><i class="icon-pie-chart"></i><p class="d-none">-</p></span><span class="text-uppercase neusa-next-medium field-title"></span></div><p class="feature-title text-gray-5 field-contenttitle">The Biopharmaceutical Research Ecosystem – Five Things You Need to Know</p></div></div></a> </div> </div> <div class="component phrma-content-promo feature-item side-bar ico-secondary-orange text-secondary-orange"> <div class="component-content"> <a title="2024 PhRMA Annual Membership Survey" href="/resource-center/Topics/Research-and-Development/2024-PhRMA-Annual-Membership-Survey"><div><div class="feature-image-container"><img src="/-/media/Project/PhRMA/PhRMA-Org/PhRMA-Refresh/Teaser-Image/P-R/2024PhRMAAnnualMembershipSurvey_Teaser_635.png?w=403&hash=6E69615A0CEACF42CC91AE6BC37F4BD0" sizes="(max-width: 767px) 707px, (max-width: 991px) 451px, 403px" srcset="/-/media/Project/PhRMA/PhRMA-Org/PhRMA-Refresh/Teaser-Image/P-R/2024PhRMAAnnualMembershipSurvey_Teaser_635.png?w=707&hash=640BEE7FAD7BB817F1BD07131D469A4F 707w,/-/media/Project/PhRMA/PhRMA-Org/PhRMA-Refresh/Teaser-Image/P-R/2024PhRMAAnnualMembershipSurvey_Teaser_635.png?w=+451&hash=990F335DB85541EA13F875C35B792E4C 451w,/-/media/Project/PhRMA/PhRMA-Org/PhRMA-Refresh/Teaser-Image/P-R/2024PhRMAAnnualMembershipSurvey_Teaser_635.png?w=+403&hash=37D4A8C74FF0FBBDE8D865ECB2BA5812 403w"></img></div><div class="feature-content-area bg-sky-blue-l10-clear"><div class="rf-btn-link"><span class="pr-2 field-markup"><i class="icon-file-text"></i><p class="d-none">-</p></span><span class="text-uppercase neusa-next-medium field-title"></span></div><p class="feature-title text-gray-5 field-contenttitle">2024 PhRMA Annual Membership Survey</p></div></div></a> </div> </div> <div class="component phrma-content-promo feature-item side-bar"> <div class="component-content"> <a title="Innovation in the Biopharmaceutical Pipeline" href="/resource-center/Topics/Innovation/Innovation-in-the-Biopharmaceutical-Pipeline"><div><div class="feature-image-container"><img src="/-/media/Project/PhRMA/PhRMA-Org/PhRMA-Org/P---R/Resource-Thumbnail.png?w=403&hash=5CA83C7BCAACA8A511E90FEDF46B3F92" alt="Innovation in the Biopharmaceutical Pipeline" sizes="(max-width: 767px) 707px, (max-width: 991px) 451px, 403px" srcset="/-/media/Project/PhRMA/PhRMA-Org/PhRMA-Org/P---R/Resource-Thumbnail.png?w=707&hash=8AF756862C0587D153FDCA27C95EFA75 707w,/-/media/Project/PhRMA/PhRMA-Org/PhRMA-Org/P---R/Resource-Thumbnail.png?w=+451&hash=768C0FAB53181FA7A6B9AB9034E1FD30 451w,/-/media/Project/PhRMA/PhRMA-Org/PhRMA-Org/P---R/Resource-Thumbnail.png?w=+403&hash=95520BDBDFF9C0BF1232BE606E7B95EF 403w"></img></div><div class="feature-content-area bg-sky-blue-l10-clear"><div class="rf-btn-link"><span class="pr-2 field-markup"><i class="icon-file-text"></i><p class="d-none">-</p></span><span class="text-uppercase neusa-next-medium field-title"></span></div><p class="feature-title text-gray-5 field-contenttitle">Innovation in the Biopharmaceutical Pipeline</p></div></div></a> </div> </div> </div></section></div> </div> </div> <div class="component cmp-basic-content container-fluid pt-0 ico-primary-red"> <div class="component-content"> <div class="jump-link-text d-none field-jump-nav-link-text"></div><div class="container"><div class="basic-content-header text-center"><span class="large-icon text-magenta field-markup"><i class="icon-medicine"></i><p class="d-none">-</p></span><h2 class="headline field-basiccontentheadline">Progress toward New Medicines and Vaccines</h2><h4 class="sub-headline text-gray-300 field-basiccontentsubheadline"></h4></div><section class="row mx-0 px-0 px-lg-3 px-xl-0 py-0"><div class="field-basiccontentrichtext"><p>The biopharmaceutical industry utilizes its scientific and industrial expertise to build on and advance basic science research into safe and effective treatments and vaccines that can be made available to patients. The biopharmaceutical industry is uniquely positioned to take on the necessary risk to advance research into safe and effective treatments. For example: </p> <ul> <li>On average, it takes 10-15 years and costs $2.6 billion to develop one new medicine, including the cost of the many failures.</li> <li>Only 12% of new molecular entities that enter clinical trials eventually receive U.S. Food and Drug Administration (FDA) approval. </li> <li>Approximately 7,000 rare diseases exist today yet only 5% have an available treatment.</li> <li>The decades-long investments biopharmaceutical companies have made in new technologies, research and previous vaccines prepared the industry to act swiftly to respond to the COVID-19 pandemic.</li> <li>A vast array of public-private <a href="/resource-center/Topics/Science/Public-Private-Collaboration-Fuels-the-US-Biopharmaceutical-Ecosystem" target="_blank">partnerships</a> between the biopharmaceutical industry, academia and public sector enables us to expand the frontier of science. Importantly, the biopharmaceutical industry spends on average three times the amount on R&D each year than the total annual budget of the NIH.</li> </ul></div></section></div> </div> </div> <div> <section class="component cmp-carousel " id=""> <div class="container"> <div class="row"> <div class="col-12 text-center"> <h2>Related Resources</h2> </div> <div class="owl-carousel owl-theme"> <div class="component phrma-content-promo"> <div class="component-content"> <div><div class="feature-item"><a title="Medicines in Development" href="/Scientific-Innovation/In-The-Pipeline/Medicines-in-Development"><div class="feature-image-container"><img src="/-/media/Project/PhRMA/PhRMA-Org/PhRMA-Org/Teaser-Image/meds-in-dev_1000x635_mid_copy.jpg?w=416&hash=DD607B495575F4F25081CE3FF51C11A9" sizes="(max-width: 767px) 737px, 416px" srcset="/-/media/Project/PhRMA/PhRMA-Org/PhRMA-Org/Teaser-Image/meds-in-dev_1000x635_mid_copy.jpg?w=737&hash=B7FFDBF8CCDE91FE124C5616FDD4E9A0 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href="/resource-center/Topics/Access-to-Medicines/Accelerated-approval-Bringing-patients-access-to-needed-medicines">Accelerated approval: Bringing patients access to needed medicines</a></h3><p class="feature-type"><em class="feature-type field-title"></em></p><div class="mb-3"><a title="Accelerated approval Bringing patients access to needed medicines" href="/resource-center/Topics/Access-to-Medicines/Accelerated-approval-Bringing-patients-access-to-needed-medicines"><span class="rf-btn-link rf-btn-link-magenta with-caret text-uppercase">fact sheet</span></a></div></div></div></div> </div> </div> <div class="component phrma-content-promo"> <div class="component-content"> <div><div class="feature-item"><a title="Development of new medicines relies on private sector expertise and investment" href="/Coronavirus/Development-of-new-medicines-relies-on-private-sector-expertise-and-investment"><div class="feature-image-container"><img src="/-/media/Project/PhRMA/PhRMA-Org/PhRMA-Org/cov/Screenshot-2021-10-08-144648.png?w=416&hash=96AF55F4D07C960D7DA587E92F629E92" alt="Illustration of a scientist looking through a microscope" sizes="(max-width: 767px) 737px, 416px" srcset="/-/media/Project/PhRMA/PhRMA-Org/PhRMA-Org/cov/Screenshot-2021-10-08-144648.png?w=737&hash=11C697B33672CFB0FD2C051C5DC40669 737w,/-/media/Project/PhRMA/PhRMA-Org/PhRMA-Org/cov/Screenshot-2021-10-08-144648.png?w=+416&hash=98A9A266C927F9CE3EAD476EECE50F00 416w"></img></div></a><div class="feature-content-area d-flex justify-content-end flex-column align-items-center"><h3 class="feature-title field-contenttitle"><a title="Development of new medicines relies on private sector expertise and investment" href="/Coronavirus/Development-of-new-medicines-relies-on-private-sector-expertise-and-investment">Development of new medicines relies on private sector expertise and investment</a></h3><p class="feature-type"><em class="feature-type field-title"></em></p><div class="mb-3"><a title="Development of new medicines relies on private sector expertise and investment" href="/Coronavirus/Development-of-new-medicines-relies-on-private-sector-expertise-and-investment"><span class="rf-btn-link rf-btn-link-magenta with-caret text-uppercase">fact sheet</span></a></div></div></div></div> </div> </div> <div class="component phrma-content-promo"> <div class="component-content"> <div><div class="feature-item"><a title="The Unique R and D Ecosystem Delivering New Treatments and Cures to Patients" href="/resource-center/Topics/Research-and-Development/The-Unique-R-and-D-Ecosystem-Delivering-New-Treatments-and-Cures-to-Patients"><div class="feature-image-container"><img src="/-/media/Project/PhRMA/PhRMA-Org/PhRMA-Org/S---U/unique_ecosystem_1000x635.jpg?w=416&hash=13C285F176DCF12C5CAC4A1658D86FBF" alt="A photograph of a woman and child speaking to a male doctor, who is holding an inhaler" sizes="(max-width: 767px) 737px, 416px" srcset="/-/media/Project/PhRMA/PhRMA-Org/PhRMA-Org/S---U/unique_ecosystem_1000x635.jpg?w=737&hash=C1E212711A953B583BA4B3B2BE6A31A4 737w,/-/media/Project/PhRMA/PhRMA-Org/PhRMA-Org/S---U/unique_ecosystem_1000x635.jpg?w=+416&hash=30E0AF588BAD8F2DDB6DD64329FFBB6B 416w"></img></div></a><div class="feature-content-area d-flex justify-content-end flex-column align-items-center"><h3 class="feature-title field-contenttitle"><a title="The Unique R and D Ecosystem Delivering New Treatments and Cures to Patients" href="/resource-center/Topics/Research-and-Development/The-Unique-R-and-D-Ecosystem-Delivering-New-Treatments-and-Cures-to-Patients">The Unique R&D Ecosystem: Delivering New Treatments and Cures to Patients</a></h3><p class="feature-type"><em class="feature-type field-title">Video</em></p><a title="The Unique R and D Ecosystem Delivering New Treatments and Cures to Patients" href="/resource-center/Topics/Research-and-Development/The-Unique-R-and-D-Ecosystem-Delivering-New-Treatments-and-Cures-to-Patients"><span class="rf-btn-link text-uppercase mb-3"><span class="field-markup pr-1"><i class="icon-play"></i></span><span class="field-linktext">Watch Video</span></span></a></div></div></div> </div> </div> <div class="component phrma-content-promo"> <div class="component-content"> <div><div class="feature-item"><a title="Public Private Collaboration Fuels the US Biopharmaceutical Ecosystem" href="/resource-center/Topics/Science/Public-Private-Collaboration-Fuels-the-US-Biopharmaceutical-Ecosystem"><div class="feature-image-container"><img src="/-/media/Project/PhRMA/PhRMA-Org/PhRMA-Org/G---I/Helix_infographic_92320_1000_x_635.jpg?w=416&hash=E0D009E9848D860810154EDEDA94A2FE" alt="An image featuring PhRMA's infographic on Public-Private Collaboration in the biopharmaceutical ecosystem" sizes="(max-width: 767px) 737px, 416px" srcset="/-/media/Project/PhRMA/PhRMA-Org/PhRMA-Org/G---I/Helix_infographic_92320_1000_x_635.jpg?w=737&hash=DD0E917982FF06F1B1FAABC094D0DAE6 737w,/-/media/Project/PhRMA/PhRMA-Org/PhRMA-Org/G---I/Helix_infographic_92320_1000_x_635.jpg?w=+416&hash=9B36BE6CD25F1530873F4B51CC567D6D 416w"></img></div></a><div class="feature-content-area d-flex justify-content-end flex-column align-items-center"><h3 class="feature-title field-contenttitle"><a title="Public Private Collaboration Fuels the US Biopharmaceutical Ecosystem" href="/resource-center/Topics/Science/Public-Private-Collaboration-Fuels-the-US-Biopharmaceutical-Ecosystem">Public-Private Collaboration Fuels the US Biopharmaceutical Ecosystem</a></h3><p class="feature-type"><em class="feature-type field-title">Graphic</em></p><div class="mb-3"><a title="Public Private Collaboration Fuels the US Biopharmaceutical Ecosystem" href="/resource-center/Topics/Science/Public-Private-Collaboration-Fuels-the-US-Biopharmaceutical-Ecosystem"><span class="rf-btn-link rf-btn-link-magenta with-caret text-uppercase">Read More</span></a></div></div></div></div> </div> </div> <div class="component phrma-content-promo"> <div class="component-content"> <div><div class="feature-item"><a title="Biopharmaceutical Innovation in Fighting HIV-AIDS" href="/resource-center/Topics/Disease/Biopharmaceutical-Innovation-in-Fighting-HIV-AIDS"><div class="feature-image-container"><img src="/-/media/Project/PhRMA/PhRMA-Org/PhRMA-Org/G---I/HIV-one-pager_TeaserWeb_1000x635.png?w=416&hash=69FED1E29395DD7D48A2CE06D57E90DF" alt="Chemist in laboratory examining a test tube of red liquid" sizes="(max-width: 767px) 737px, 416px" srcset="/-/media/Project/PhRMA/PhRMA-Org/PhRMA-Org/G---I/HIV-one-pager_TeaserWeb_1000x635.png?w=737&hash=A6B679CB521658CB10EC1E440EE56971 737w,/-/media/Project/PhRMA/PhRMA-Org/PhRMA-Org/G---I/HIV-one-pager_TeaserWeb_1000x635.png?w=+416&hash=C5310BD5E4A014DEBA2D2C70A3722DFA 416w"></img></div></a><div class="feature-content-area d-flex justify-content-end flex-column align-items-center"><h3 class="feature-title field-contenttitle"><a title="Biopharmaceutical Innovation in Fighting HIV-AIDS" href="/resource-center/Topics/Disease/Biopharmaceutical-Innovation-in-Fighting-HIV-AIDS">Biopharmaceutical Innovation in Fighting HIV/AIDS</a></h3><p class="feature-type"><em class="feature-type field-title"></em></p><div class="mb-3"><a title="Biopharmaceutical Innovation in Fighting HIV-AIDS" href="/resource-center/Topics/Disease/Biopharmaceutical-Innovation-in-Fighting-HIV-AIDS"><span class="rf-btn-link rf-btn-link-magenta with-caret text-uppercase">Fact sheet</span></a></div></div></div></div> </div> </div> <div class="component phrma-content-promo"> <div class="component-content"> <div><div class="feature-item"><a title="Medicine Development in a Complex Collaborative Ecosystem" href="/resource-center/Topics/Medicine-in-Development/Medicine-Development-in-a-Complex-Collaborative-Ecosystem"><div class="feature-image-container"><img src="/-/media/Project/PhRMA/PhRMA-Org/PhRMA-Org/M---O/Medicine-Development-in-a-Complex-Collaborative-Ecosystem-Image.jpg?w=416&hash=8AF7E928C7D7FF04A82B9B4630017146" alt="Medicine Development in a Complex, Collaborative Ecosystem teaser graphic" sizes="(max-width: 767px) 737px, 416px" srcset="/-/media/Project/PhRMA/PhRMA-Org/PhRMA-Org/M---O/Medicine-Development-in-a-Complex-Collaborative-Ecosystem-Image.jpg?w=737&hash=24930C6985345CF31B0939F60906BB9A 737w,/-/media/Project/PhRMA/PhRMA-Org/PhRMA-Org/M---O/Medicine-Development-in-a-Complex-Collaborative-Ecosystem-Image.jpg?w=+416&hash=C78A0A16EEDDBD69EE45C2380EB9D6EC 416w"></img></div></a><div class="feature-content-area d-flex justify-content-end flex-column align-items-center"><h3 class="feature-title field-contenttitle"><a title="Medicine Development in a Complex Collaborative Ecosystem" href="/resource-center/Topics/Medicine-in-Development/Medicine-Development-in-a-Complex-Collaborative-Ecosystem">Medicine Development in a Complex, Collaborative Ecosystem</a></h3><p class="feature-type"><em class="feature-type field-title">Graphic</em></p><div class="mb-3"><a title="Medicine Development in a Complex Collaborative Ecosystem" href="/resource-center/Topics/Medicine-in-Development/Medicine-Development-in-a-Complex-Collaborative-Ecosystem"><span class="rf-btn-link rf-btn-link-magenta with-caret text-uppercase">Read More</span></a></div></div></div></div> </div> </div> </div> </div> </div> </section> </div> <div class="component cmp-basic-content container-fluid"> <div class="component-content"> <div class="jump-link-text d-none field-jump-nav-link-text"></div><div class="container"><div class="basic-content-header text-center"><span class="large-icon text-magenta field-markup"><i class="icon-flask"></i><p class="d-none">-</p></span><h2 class="headline field-basiccontentheadline">Advances in Treatment</h2><h4 class="sub-headline text-gray-300 field-basiccontentsubheadline"></h4></div><section class="row mx-0 px-0 px-lg-3 px-xl-0 py-0"><div class="field-basiccontentrichtext"><ul style="list-style-type: disc;"> <li><strong><span style="color: #252727;">Progress in the fight against cancer: </span></strong><span style="color: #252727;">Since peaking in 1991, the cancer death rate in the United States has decreased by more than 33%. This progress is due in large part to new treatment advances in oncology like precision medicine, immunotherapy and CAR-T cell therapy.</span></li> <li><strong><span style="color: #252727;">Turning HIV/AIDs into a treatable chronic condition. </span></strong><span style="color: #252727;">The introduction of highly active antiretroviral therapy (HAART) in the mid-1990s, which transformed treatment leading to over 90% decline in death rates and preventing an estimated 862,000 premature deaths.</span></li> <li><strong><span style="color: #252727;">Harnessing the medical power of the genome</span></strong><span style="color: #252727;">. In recent years, biopharmaceutical scientists have been harnessing the power of cell and gene therapies to treat and potentially cure a range of diseases from cancer to disorders of the blood.</span></li> </ul></div></section></div> </div> </div> <div class="component cmp-basic-content container-fluid ico-primary-red"> <div class="component-content"> <div class="jump-link-text d-none field-jump-nav-link-text"></div><div class="container"><div class="basic-content-header text-center"><span class="large-icon text-magenta field-markup"><i class="icon-beaker-alt"></i><p class="d-none">-</p></span><h2 class="headline field-basiccontentheadline">Committed to Research</h2><h4 class="sub-headline text-gray-300 field-basiccontentsubheadline"></h4></div><section class="row mx-0 px-0 px-lg-3 px-xl-0 py-0"><div class="field-basiccontentrichtext"><p>All of PhRMA’s member companies meet the following criteria:</p> <ul style="list-style-type: disc;"> <li>A three-year average global R&D to global sales ratio of 10% or greater; and</li> <li>A three-year average global R&D spending of at least $200 million per year.</li> </ul> <p>PhRMA member companies have invested over $1 trillion dollars in R&D since 2000, establishing the biopharmaceutical sector as the most R&D-intensive industry in the U.S. economy. In fact, the biopharmaceutical industry invests on average six times more in R&D as a percentage of sales than all other manufacturing industries.</p> <p>Through investment in R&D, biopharmaceutical researchers and scientists have gained a better understanding of diseases and a greater ability to harness new scientific advances, leading to tremendous progress in the development of treatments and cures for some of the most debilitating diseases patients face. </p> <p><em>Updated as of September 2024.</em></p></div></section></div> </div> </div> <div class="component container"> <div class="component-content" > <div class="component cmp-basic-content section-tile-gallery bg-stripe"> <div class="component-content"> <div class="basic-content-header text-center tile-gallery-header pb-0"><h4 class="text-magenta sup-headline field-basiccontentsupheadline">Read more about</h4><h2 class="headline text-navy field-basiccontentheadline">Research & Development</h2></div><div class="component 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href="/policy-issues/Research-and-Development-Policy-Framework/Biologics-Biosimilars"><span class="rf-btn-link with-caret text-uppercase"><span class="field-linktext">Learn More</span></span></a></div></div> </li> <li class="item"> <div class="gallery-tile col-md-4"><div class="gallery-image"><img src="/-/media/Project/PhRMA/PhRMA-Org/PhRMA-Org/Teaser-Image/mid_meds4.jpg?w=403&hash=A108B88B53A9C227BEBC071714686A1E" alt="Man taking an orange pill" sizes="(max-width: 650px) 590px, (max-width: 1020px) 480px, 403px" srcset="/-/media/Project/PhRMA/PhRMA-Org/PhRMA-Org/Teaser-Image/mid_meds4.jpg?w=590&hash=B50FF82873EB22C8C39E46A550975A39 590w,/-/media/Project/PhRMA/PhRMA-Org/PhRMA-Org/Teaser-Image/mid_meds4.jpg?w=+480&hash=ADD368E6166C947F39E2468D277441DE 480w,/-/media/Project/PhRMA/PhRMA-Org/PhRMA-Org/Teaser-Image/mid_meds4.jpg?w=+403&hash=66365D4D2A9C9AC5C6B6106719B965EE 403w"></img></div><div class="feature-content-area bg-sky-blue-l10-clear"><p class="text-navy neusa-next-regular mb-0 field-contenttitle">Clinical Trials</p><a title="Clinical Trials" href="/policy-issues/Research-and-Development-Policy-Framework/Clinical-Trials"><span class="rf-btn-link with-caret text-uppercase"><span class="field-linktext">Learn More</span></span></a></div></div> </li> <li class="item"> <div class="gallery-tile col-md-4"><div class="gallery-image"><img src="/-/media/Project/PhRMA/PhRMA-Org/PhRMA-Org/Teaser-Image/md_1000x635_pediatrics.jpg?w=403&hash=78E2AD578F2D29FF80770E09D44610F5" alt="Doctor looking through a stethoscope to check a young girls ears." sizes="(max-width: 650px) 590px, (max-width: 1020px) 480px, 403px" srcset="/-/media/Project/PhRMA/PhRMA-Org/PhRMA-Org/Teaser-Image/md_1000x635_pediatrics.jpg?w=590&hash=787DF725DE26CC319BAFA10708AA0F85 590w,/-/media/Project/PhRMA/PhRMA-Org/PhRMA-Org/Teaser-Image/md_1000x635_pediatrics.jpg?w=+480&hash=F4DAEE957C09F22EFFB04420B4206D62 480w,/-/media/Project/PhRMA/PhRMA-Org/PhRMA-Org/Teaser-Image/md_1000x635_pediatrics.jpg?w=+403&hash=A2EAA6DEAD7D804EAC00F788BB75FA61 403w"></img></div><div class="feature-content-area bg-sky-blue-l10-clear"><p class="text-navy neusa-next-regular mb-0 field-contenttitle">Pediatrics</p><a href="/Scientific-Innovation/Pediatrics"><span class="rf-btn-link with-caret text-uppercase"><span class="field-linktext">Learn More</span></span></a></div></div> </li> <li class="item"> <div class="gallery-tile col-md-4"><div class="gallery-image"><img src="/-/media/Project/PhRMA/PhRMA-Org/PhRMA-Org/Teaser-Image/mid_molecule4.jpg?w=403&hash=EE9CEE7FA4463335C2AEFFAE88E617FF" alt="Model of molecules" sizes="(max-width: 650px) 590px, (max-width: 1020px) 480px, 403px" srcset="/-/media/Project/PhRMA/PhRMA-Org/PhRMA-Org/Teaser-Image/mid_molecule4.jpg?w=590&hash=E33D1CE931748DFADB65A2CDCF0E5E68 590w,/-/media/Project/PhRMA/PhRMA-Org/PhRMA-Org/Teaser-Image/mid_molecule4.jpg?w=+480&hash=10E9F939371C1D5F015DD01F90E6BF9E 480w,/-/media/Project/PhRMA/PhRMA-Org/PhRMA-Org/Teaser-Image/mid_molecule4.jpg?w=+403&hash=31A236FDF990CC68022D7027D37C5AB8 403w"></img></div><div class="feature-content-area bg-sky-blue-l10-clear"><p class="text-navy neusa-next-regular mb-0 field-contenttitle">Regulatory Harmonization</p><a title="Regulatory Harmonization" href="/policy-issues/Research-and-Development-Policy-Framework/Regulatory-Harmonization"><span class="rf-btn-link with-caret text-uppercase"><span class="field-linktext">Learn More</span></span></a></div></div> </li> <li class="item"> <div class="gallery-tile col-md-4"><div class="gallery-image"><img src="/-/media/Project/PhRMA/PhRMA-Org/PhRMA-Org/S---U/stem_1000x635_mid.jpg?w=403&hash=9A8D4F19F8AFD529EC1A9F074F4F31A5" alt="STEM Education" sizes="(max-width: 650px) 590px, (max-width: 1020px) 480px, 403px" srcset="/-/media/Project/PhRMA/PhRMA-Org/PhRMA-Org/S---U/stem_1000x635_mid.jpg?w=590&hash=04A945B5C138D6624BF16E23F71B0AEA 590w,/-/media/Project/PhRMA/PhRMA-Org/PhRMA-Org/S---U/stem_1000x635_mid.jpg?w=+480&hash=8DD4B6109FCB434250ECA65429FA5F6F 480w,/-/media/Project/PhRMA/PhRMA-Org/PhRMA-Org/S---U/stem_1000x635_mid.jpg?w=+403&hash=2FBD04FEE32977B31EB68B0140C2E948 403w"></img></div><div class="feature-content-area bg-sky-blue-l10-clear"><p class="text-navy neusa-next-regular mb-0 field-contenttitle">STEM: Growing Our Next Generation of Innovators</p><a href="/resource-center/Topics/STEM/STEM-Growing-Our-Next-Generation-of-Innovators"><span class="rf-btn-link with-caret text-uppercase"><span class="field-linktext">Learn More</span></span></a></div></div> </li> <li class="item"> <div class="gallery-tile col-md-4"><div class="gallery-image"><img src="/-/media/Project/PhRMA/PhRMA-Org/PhRMA-Org/V---Z/Vaccines-2-md.jpg?w=403&hash=644E17D500A678FE685B41446CF05662" alt="Close up view of vaccines shots" sizes="(max-width: 650px) 590px, (max-width: 1020px) 480px, 403px" srcset="/-/media/Project/PhRMA/PhRMA-Org/PhRMA-Org/V---Z/Vaccines-2-md.jpg?w=590&hash=EF6C1F655B4CC30EADEBDBFA96D474C2 590w,/-/media/Project/PhRMA/PhRMA-Org/PhRMA-Org/V---Z/Vaccines-2-md.jpg?w=+480&hash=423A72367D1C6AF1DFD3683B6C083EA9 480w,/-/media/Project/PhRMA/PhRMA-Org/PhRMA-Org/V---Z/Vaccines-2-md.jpg?w=+403&hash=BBF997BC00B113E020214605CE37ED73 403w"></img></div><div class="feature-content-area bg-sky-blue-l10-clear"><p class="text-navy neusa-next-regular mb-0 field-contenttitle">Vaccines</p><a href="/resource-center/Topics/Science/New-Era-of-Medicine-Vaccines"><span class="rf-btn-link with-caret text-uppercase"><span class="field-linktext">Learn More</span></span></a></div></div> </li> </ul> </div> </div> </div> </div> </div> </div> <div class="component cmp-basic-content bg-gray-1"> <div class="component-content"> <div class="container"><div class="basic-content-header text-center latest-blog-heading"><h2 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