Proteome Profiler Rat XL Cytokine Array ARY030: R&D Systems

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id="content_column"> <div class="ds_title_table"> <h1 class="ds_title">Proteome Profiler Rat XL Cytokine Array </h1> <div class="dsSprite_rnd ds_brand_logo ds_rnd_logo"></div> </div> <div class="product_meta"> <span class="category_number">Catalog #: ARY030</span> <br/> <span class="citations"> <a href="#product-citations" id="citation_count" class="jump_to" data-tab="3" data-tabname="product-citations"> 13 Citations </a> </span> <span class="reviews review_stars_5"> <a href="#product-reviews" id="product_reviews" class="jump_to" data-tab="6" data-tabname="product-reviews"> 2 Reviews </a> </span> <a href="/reviews/ARY030" rel="nofollow"><span class="submit_review"><button class="btn btn-quaternary">Submit a Review</button></span></a> <span class="datasheet_link"> <a href="#product-datasheets">Datasheet / COA / SDS</a> </span> </div> <div class="product_info">Contains 4 membranes-each spotted in duplicate with 79 different cytokine antibodies</div>  <div class="product_wrapper row"> <div class="product_ordering_wrapper col-xs-12 col-md-8 col-md-push-4"> <div class="product_ordering"> <form action="/products/proteome-profiler-rat-xl-cytokine-array_ary030" method="post" id="atc-datasheet-form" accept-charset="UTF-8"><div><div id="atc_datasheet_block">     <table class="add_to_cart"> <thead> <tr> <th class="ds_catalog">Catalog #</th> <th class="ds_availability_column mobile-hide">Availability</th> <th class="ds_size_price_column">Size / Price</th> <th class="ds_quantity_column">Qty</th> </tr> </thead> <tbody> <tr class="et_atc_product" data-sku="ARY030"> <td class="dat_catalog_column">ARY030</td> <td class="et_atc_results" colspan="2"></td> <td class="ds_quantity ds_quantity_column"><div class="form-item form-item-catnum-ary030 form-type-textfield form-group"><input class="atc_quantity atc_hidden atc_qty form-control form-text" placeholder="0" style="display:none;" type="text" id="edit-catnum-ary030" name="catnum-ARY030" value="" size="5" maxlength="3" /></div></td> </tr> </tbody> </table> <div class="ds_atc_pre_buttons"></div> <div class="ds_atc_buttons"> <a href="/quote/instruments/ella-automated-immunoassay-system" class="btn btn-secondary atc_request_quote_simple_plex_assay" style="display:none" rel="nofollow">Request a Quote</a> <a href="/services/bulk-quote-request?catnum=ARY030&product=Proteome Profiler Rat XL Cytokine Array" class="btn btn-secondary atc_hidden bulk_btn" style="display:none;" rel="nofollow" title="Competitive discounts on products purchased in bulk quantities">Bulk Orders</a> <button class="btn btn-primary atc_hidden atc_btn form-submit icon-before" style="display:none;" title="Enter quantities above and click to add to cart" type="submit" id="edit-add-to-cart" name="add_to_cart_btn" value="Add to Cart"><span class="icon glyphicon glyphicon-plus" aria-hidden="true"></span> Add to Cart</button> </div> <div class="ds_atc_post_buttons"></div> </div> <input type="hidden" name="form_build_id" value="form-CRY9faDKa6vJLS379o4kgJG4-R2bYhZAbD3IQ7xTv6k" /> <input type="hidden" name="form_id" value="atc_datasheet_form" /> </div></form> </div> </div> <div class="product_image_wrapper col-xs-12 col-md-4 col-md-pull-8"> <div class="product_image"> <span class="product_image_label"> </span> <a class="ds-image overview-images" data-toggle="lightbox" data-gallery="overview-images" onClick="event.preventDefault();" data-title="The Mouse XL Cytokine Array detects multiple cytokines, chemokines, growth factors and other soluble proteins in cell culture supernates." data-footer="The Mouse XL Cytokine Array detects multiple cytokines, chemokines, growth factors and other soluble proteins in cell culture supernates." title="Cat. No. ARY030 - Proteome Profiler Rat XL Cytokine Array" href="https://resources.rndsystems.com/images/datasheets/ary030_proteome-profiler-rat-xl-cytokine-array-5112020143855.png"> <img fetchpriority="high" src="https://resources.rndsystems.com/images/datasheets/ary030_proteome-profiler-rat-xl-cytokine-array-5112020143855.png" class="img-fluid" alt="The Mouse XL Cytokine Array detects multiple cytokines, chemokines, growth factors and other soluble proteins in cell culture supernates." title="The Mouse XL Cytokine Array detects multiple cytokines, chemokines, growth factors and other soluble proteins in cell culture supernates."> </a> <div class="search_image_other_count"> <span class="search_more_images">4 Images</span> </div> </div> </div> <div id="extra_images overview-images" class="hidden"> <a class="ds-image" data-toggle="lightbox" data-gallery="overview-images" data-footer="The Mouse XL Cytokine Array detects multiple cytokines, chemokines, growth factors and other soluble proteins in cell culture supernates." data-title="The Mouse XL Cytokine Array detects multiple cytokines, chemokines, growth factors and other soluble proteins in cell culture supernates." title="Cat. No. ARY030 - Proteome Profiler Rat XL Cytokine Array" onClick="event.preventDefault();" href="https://resources.rndsystems.com/images/datasheets/ary030_proteome-profiler-rat-xl-cytokine-array-5112020143958.png"> <img src="https://resources.rndsystems.com/images/datasheets/ary030_proteome-profiler-rat-xl-cytokine-array-5112020143958.png" class="img-fluid" loading="lazy" alt="The Mouse XL Cytokine Array detects multiple cytokines, chemokines, growth factors and other soluble proteins in cell culture supernates." title="The Mouse XL Cytokine Array detects multiple cytokines, chemokines, growth factors and other soluble proteins in cell culture supernates."> </a> <a class="ds-image" data-toggle="lightbox" data-gallery="overview-images" data-footer="The Mouse XL Cytokine Array detects multiple cytokines, chemokines, growth factors and other soluble proteins in cell culture supernates." data-title="The Mouse XL Cytokine Array detects multiple cytokines, chemokines, growth factors and other soluble proteins in cell culture supernates." title="Cat. No. ARY030 - Proteome Profiler Rat XL Cytokine Array" onClick="event.preventDefault();" href="https://resources.rndsystems.com/images/datasheets/ary030_proteome-profiler-rat-xl-cytokine-array-5112020144051.png"> <img src="https://resources.rndsystems.com/images/datasheets/ary030_proteome-profiler-rat-xl-cytokine-array-5112020144051.png" class="img-fluid" loading="lazy" alt="The Mouse XL Cytokine Array detects multiple cytokines, chemokines, growth factors and other soluble proteins in cell culture supernates." title="The Mouse XL Cytokine Array detects multiple cytokines, chemokines, growth factors and other soluble proteins in cell culture supernates."> </a> <a class="ds-image" data-toggle="lightbox" data-gallery="overview-images" data-footer="The Mouse XL Cytokine Array detects multiple cytokines, chemokines, growth factors and other soluble proteins in cell culture supernates." data-title="The Mouse XL Cytokine Array detects multiple cytokines, chemokines, growth factors and other soluble proteins in cell culture supernates." title="Cat. No. ARY030 - Proteome Profiler Rat XL Cytokine Array" onClick="event.preventDefault();" href="https://resources.rndsystems.com/images/datasheets/ary030_proteome-profiler-rat-xl-cytokine-array-5112020144155.png"> <img src="https://resources.rndsystems.com/images/datasheets/ary030_proteome-profiler-rat-xl-cytokine-array-5112020144155.png" class="img-fluid" loading="lazy" alt="The Mouse XL Cytokine Array detects multiple cytokines, chemokines, growth factors and other soluble proteins in cell culture supernates." title="The Mouse XL Cytokine Array detects multiple cytokines, chemokines, growth factors and other soluble proteins in cell culture supernates."> </a> </div> </div> <div class="product_info_wrapper"> </div> <div id="view-more-target" class="datasheet_section_element"> View <a href="/target/multiplex-cytokine-assay-kits">All Products for Multiplex Cytokine Assay Kits</a> </div> </div>  <div class="tabbed_content" id="rnd_atlantabio">  <div id="ds_tabs" class="tab_menu"> <div class="tab tab_1 tab_open" data-tab="1" data-tabname="product-details" id="dsTabs_product-details"> <span>Product Details</span> </div> <div class="tab tab_3" data-tab="3" data-tabname="product-citations" id="dsTabs_product-citations"> <span>Citations (13)</span> </div> <div class="tab tab_4" data-tab="4" data-tabname="faqs" id="dsTabs_faqs"> <span>FAQs</span> </div> <div class="tab tab_6" data-tab="6" data-tabname="product-reviews" id="dsTabs_product-reviews"> <span> Reviews (2) </span> </div> </div>  <div class="tab_content tab_1 tab_open" data-tab="1" data-tabname="product-details" id="product-details"> <div class="datasheet_section_element"> <a class="btn btn-quaternary scroll_to anchor-link" href="#ds_summary" id="product-anchor-ds_summary">Summary</a> <a class="btn btn-quaternary scroll_to anchor-link" href="#ds_datasheets" id="product-anchor-ds_datasheets">Product Datasheets</a> <a class="btn btn-quaternary scroll_to anchor-link" href="#ds_data_examples" id="product-anchor-ds_data_examples">Data Images</a> </div> <div id="ds_summary" class="datasheet_section"> <h2>Proteome Profiler Rat XL Cytokine Array Summary</h2> <div id="ds_product_details" class="datasheet_section"> <style type="text/css">table.detect tr:nth-child(even) {background-color: #e7e7e7;} </style> <div class="ds_lightBlueBar">Kit Summary</div> <h2>A membrane-based antibody array for the parallel determination of the relative levels of selected rat cytokines and chemokines. Validated for analyte detection in cell culture supernates, cell lysates, tissue lysates, serum, and urine.</h2> <div class="grid_6"> <h3>Key Benefits</h3> <ul> <li><strong>Detects 79 rat cytokines simultaneously</strong></li> <li><strong>Requires no specialized equipment</strong></li> <li><strong>Compatible with LI-COR and chemiluminescence detection</strong></li> </ul> </div> <h3>Principle of the Assay</h3> <p>The Proteome Profiler Rat XL Cytokine Array Kit is a membrane-based sandwich immunoassay. Capture antibodies spotted in duplicate on nitrocellulose membranes bind to specific target proteins present in the sample (Step 1). Captured proteins are detected with biotinylated detection antibodies (Step 2) and then visualized using chemiluminescent detection reagents (Step 3). The signal produced is proportional to the amount of analyte bound.</p> <h3>Why Use an Antibody Array to Detect Multiple Cytokines?</h3> <p>Determining the expression of multiple cytokines in a single sample can be expensive, time consuming and can require specialized equipment. Performing multiple immunoprecipitations and Western blots requires time, labor, and reagents. The use of a multiplex antibody array to detect multiple cytokines in a single sample can be cost-effective and also save time and sample</p> <p>Kit Contents</p> <ul> <li>Rectangular 4-Well Multi-dish</li> <li>4 Rat XL Cytokine Array nitrocellulose membranes spotted with 79 different antibodies to rat cytokines</li> <li>Array Buffer 4</li> <li>Array Buffer 6</li> <li>Chemi Reagent 1</li> <li>Chemi Reagent 2</li> <li>Detection Antibody Cocktail, Rat XL Cytokine Array</li> <li>Streptavidin-HRP</li> <li>Transparency Overlay Template</li> <li>Wash Buffer Concentrate (25X)</li> </ul> <p>For a complete list of the kit contents and necessary materials, please see the Materials Provided/Other Supplies Required sections of the <a href="//resources.rndsystems.com/pdfs/datasheets/ary030.pdf">product datasheet.</a></p> <div> <table cellpadding="3" cellspacing="0" class="border detect" width="100%"> <tbody> <tr> <td class="blue_high" colspan="3" width="33%">Simultaneously detect the levels of these proteins in a single sample.</td> </tr> <tr> <td class="blue_high" width="33%">Adiponectin</td> <td class="blue_high" width="33%">Galectin-3</td> <td class="blue_high" width="33%">LIX</td> </tr> <tr> <td>CCL2/JE/MCP-1</td> <td>G-CSF</td> <td>MAG/Siglec-4a</td> </tr> <tr> <td>CCL3/CCL4/MIP-1α/β</td> <td>GDF-15</td> <td>MMP-2</td> </tr> <tr> <td>CCL5/RANTES</td> <td>GM-CSF</td> <td>MMP-3</td> </tr> <tr> <td>CCL11/Eotaxin</td> <td>Hepassocin</td> <td>MMP-9</td> </tr> <tr> <td>CCL17/TARC</td> <td>HGF</td> <td>Neprilysin/CD10</td> </tr> <tr> <td>CCL20/MIP-3α</td> <td>ICAM-1/CD54</td> <td>NOV/CCN3</td> </tr> <tr> <td>CCL21/6Ckine</td> <td>IFN-γ</td> <td>NT-3</td> </tr> <tr> <td>CCL22/MDC</td> <td>IGF-I</td> <td>NT-4</td> </tr> <tr> <td>Clusterin</td> <td>IGFBP-2</td> <td>Osteopontin (OPN)</td> </tr> <tr> <td>CNTF</td> <td>IGFBP-3</td> <td>Osteoprotegerin/TNFRSF11B</td> </tr> <tr> <td>CX3CL1/Fractalkine</td> <td>IGFBP-5</td> <td>PDGF-BB</td> </tr> <tr> <td>CXCL2/GROβ/MIP-2/CINC-3</td> <td>IGFBP-6</td> <td>Pref-1/DLK1/FA1</td> </tr> <tr> <td>CXCL7/Thymus Chemokine-1</td> <td> IL-1α/IL-1F1</td> <td>Prolactin</td> </tr> <tr> <td>Cyr61/CCN1</td> <td>IL-1β/IL-1F2</td> <td>RAGE</td> </tr> <tr> <td>Cystatin C</td> <td> IL-1ra/IL-1F3</td> <td>RBP4</td> </tr> <tr> <td>DPPIV/CD26</td> <td>IL-2</td> <td>Resistin</td> </tr> <tr> <td>EGF</td> <td>IL-3</td> <td>RGM-A</td> </tr> <tr> <td>EG-VEGF</td> <td>IL-4</td> <td>SCF</td> </tr> <tr> <td>Endostatin</td> <td>IL-6</td> <td>Serpin E1/PAI-1</td> </tr> <tr> <td>Fetuin A</td> <td>IL-13</td> <td>TIM-1/KIM-1/HAVCR</td> </tr> <tr> <td>FGF acidic</td> <td>IL-17A</td> <td>TNF-α</td> </tr> <tr> <td>FGF-7</td> <td>IL-22</td> <td>TWEAK/TNFSF12</td> </tr> <tr> <td>FGF-21</td> <td>Jagged 1</td> <td>VCAM-1/CD106</td> </tr> <tr> <td>Fibulin 3</td> <td>LIF</td> <td>VEGF</td> </tr> <tr> <td>Flt-3 Ligand</td> <td>Lipocalin-2/NGAL</td> <td>WISP-1/CCN</td> </tr> <tr> <td>Galectin-1</td> <td> </td> <td> </td> </tr> </tbody> </table> </div> <div> <h3>Assays for Analytes represented in the Rat XL Cytokine Array</h3> <table cellpadding="3" cellspacing="0" class="border detect" width="100%"> <tbody> <tr> <td class="blue_high" width="33%">Analyte</td> <td class="blue_high" width="33%">Quantikine<sup>®</sup> ELISA Kits</td> <td class="blue_high" width="33%">DuoSet<sup>® </sup>ELISA Development System</td> </tr> <tr> <td>Adiponectin</td> <td><a href="/search?keywords=RRP300" target="_parent">RRP300</a></td> <td><a href="/search?keywords=DY3100-05" target="_parent">DY3100-05</a></td> </tr> <tr> <td>CCL2/JE/MCP-1</td> <td><a href="/search?keywords=MJE00" target="_parent">MJE00</a></td> <td> </td> </tr> <tr> <td>CCL3/CCL4/MIP-1α/β</td> <td> </td> <td> </td> </tr> <tr> <td>CCL5/RANTES</td> <td> </td> <td> </td> </tr> <tr> <td>CCL11/Eotaxin</td> <td> </td> <td> </td> </tr> <tr> <td>CCL17/TARC</td> <td> </td> <td> </td> </tr> <tr> <td>CCL20/MIP-3α</td> <td> </td> <td><a href="/search?keywords=DY540" target="_parent">DY540</a></td> </tr> <tr> <td>CCL21/6Ckine</td> <td> </td> <td> </td> </tr> <tr> <td>CCL22/MDC</td> <td> </td> <td> </td> </tr> <tr> <td>Clusterin</td> <td> </td> <td> </td> </tr> <tr> <td>CNTF</td> <td> </td> <td><a href="/search?keywords=DY557" target="_parent">DY557</a></td> </tr> <tr> <td>CX3CL1/Fractalkine</td> <td> </td> <td><a href="/search?keywords=DY537" target="_parent">DY537</a></td> </tr> <tr> <td>CXCL2/GROβ/MIP-2/CINC-3</td> <td><a href="/search?keywords=RCN300" target="_parent">RCN300</a></td> <td><a href="/search?keywords=DY525" target="_parent">DY525</a></td> </tr> <tr> <td>CXCL7/Thymus Chemokine-1</td> <td> </td> <td><a href="/search?keywords=DY1116" target="_parent">DY1116</a></td> </tr> <tr> <td>Cyr61/CCN1</td> <td> </td> <td> </td> </tr> <tr> <td>Cystatin C</td> <td> </td> <td> </td> </tr> <tr> <td>DPPIV/CD26</td> <td> </td> <td> </td> </tr> <tr> <td>EGF</td> <td> </td> <td><a href="/search?keywords=DY3214" target="_parent">DY3214</a></td> </tr> <tr> <td>EG-VEGF</td> <td> </td> <td> </td> </tr> <tr> <td>Endostatin</td> <td> </td> <td> </td> </tr> <tr> <td>Fetuin A</td> <td> </td> <td> </td> </tr> <tr> <td>FGF acidic</td> <td> </td> <td> </td> </tr> <tr> <td>FGF-7</td> <td> </td> <td> </td> </tr> <tr> <td>FGF-21</td> <td> </td> <td> </td> </tr> <tr> <td>Fibulin 3</td> <td> </td> <td> </td> </tr> <tr> <td>Flt-3 Ligand</td> <td> </td> <td> </td> </tr> <tr> <td>Galectin-1</td> <td> </td> <td> </td> </tr> <tr> <td>Galectin-3</td> <td> </td> <td> </td> </tr> <tr> <td>G-CSF</td> <td> </td> <td> </td> </tr> <tr> <td>GDF-15</td> <td><a href="/search?keywords=MGD150" target="_parent">MGD150</a></td> <td> </td> </tr> <tr> <td>GM-CSF</td> <td> </td> <td><a href="/search?keywords=DY518" target="_parent">DY518</a></td> </tr> <tr> <td>Hepassocin</td> <td> </td> <td> </td> </tr> <tr> <td>HGF</td> <td> </td> <td> </td> </tr> <tr> <td>ICAM-1/CD54</td> <td><a href="/search?keywords=RIC100" target="_parent">RIC100</a></td> <td><a href="/search?keywords=DY583" target="_parent">DY583</a></td> </tr> <tr> <td>IFN-γ</td> <td><a href="/search?keywords=PRIF00" target="_parent">PRIF00</a></td> <td><a href="/search?keywords=DY585" target="_parent">DY585</a></td> </tr> <tr> <td>IGF-I</td> <td> </td> <td> </td> </tr> <tr> <td>IGFBP-2</td> <td> </td> <td> </td> </tr> <tr> <td>IGFBP-3</td> <td> </td> <td> </td> </tr> <tr> <td>IGFBP-5</td> <td> </td> <td> </td> </tr> <tr> <td>IGFBP-6</td> <td> </td> <td> </td> </tr> <tr> <td> IL-1α/IL-1F1</td> <td><a href="/search?keywords=RRA00" target="_parent">RRA00</a></td> <td><a href="/search?keywords=DY500" target="_parent">DY500</a></td> </tr> <tr> <td>IL-1β/IL-1F2</td> <td><a href="/search?keywords=PRLB00" target="_parent">PRLB00</a></td> <td><a href="/search?keywords=DY501" target="_parent">DY501</a></td> </tr> <tr> <td> IL-1ra/IL-1F3</td> <td> </td> <td> </td> </tr> <tr> <td>IL-2</td> <td><a href="/search?keywords=PR2000" target="_parent">PR2000</a></td> <td><a href="/search?keywords=DY502" target="_parent">DY502</a></td> </tr> <tr> <td>IL-3</td> <td> </td> <td> </td> </tr> <tr> <td>IL-4</td> <td><a href="/search?keywords=R4000" target="_parent">R4000</a></td> <td><a href="/search?keywords=DY504" target="_parent">DY504</a></td> </tr> <tr> <td>IL-6</td> <td><a href="/search?keywords=PR6000B" target="_parent">PR6000B</a></td> <td><a href="/search?keywords=DY506" target="_parent">DY506</a></td> </tr> <tr> <td>IL-13</td> <td> </td> <td> </td> </tr> <tr> <td>IL-17A</td> <td> </td> <td> </td> </tr> <tr> <td>IL-22</td> <td> </td> <td> </td> </tr> <tr> <td>Jagged 1</td> <td> </td> <td><a href="/search?keywords=DY599" target="_parent">DY599</a></td> </tr> <tr> <td>LIF</td> <td> </td> <td> </td> </tr> <tr> <td>Lipocalin-2/NGAL</td> <td> </td> <td><a href="/search?keywords=DY3508" target="_parent">DY3508</a></td> </tr> <tr> <td>LIX</td> <td> </td> <td><a href="/search?keywords=DY543" target="_parent">DY543</a></td> </tr> <tr> <td>MAG/Siglec-4a</td> <td> </td> <td><a href="/search?keywords=DY538" target="_parent">DY538</a></td> </tr> <tr> <td>MMP-2</td> <td> </td> <td> </td> </tr> <tr> <td>MMP-3</td> <td> </td> <td> </td> </tr> <tr> <td>MMP-9</td> <td><a href="/search?keywords=RMP900" target="_parent">RMP900</a></td> <td><a href="/search?keywords=DY8174-05" target="_parent">DY8174-05</a></td> </tr> <tr> <td>Neprilysin/CD10</td> <td> </td> <td> </td> </tr> <tr> <td>NOV/CCN3</td> <td> </td> <td> </td> </tr> <tr> <td>NT-3</td> <td> </td> <td> </td> </tr> <tr> <td>NT-4</td> <td> </td> <td> </td> </tr> <tr> <td>Osteopontin (OPN)</td> <td> </td> <td> </td> </tr> <tr> <td>Osteoprotegerin/TNFRSF11B</td> <td> </td> <td> </td> </tr> <tr> <td>PDGF-BB</td> <td><a href="/search?keywords=MBB00" target="_parent">MBB00</a></td> <td><a href="/search?keywords=DY8464-05" target="_parent">DY8464-05</a></td> </tr> <tr> <td>Pref-1/DLK1/FA1</td> <td> </td> <td> </td> </tr> <tr> <td>Prolactin</td> <td> </td> <td> </td> </tr> <tr> <td>RAGE</td> <td> </td> <td><a href="/search?keywords=DY1616" target="_parent">DY1616</a></td> </tr> <tr> <td>RBP4</td> <td> </td> <td> </td> </tr> <tr> <td>Resistin</td> <td> </td> <td> </td> </tr> <tr> <td>RGM-A</td> <td> </td> <td> </td> </tr> <tr> <td>SCF</td> <td> </td> <td> </td> </tr> <tr> <td>Serpin E1/PAI-1</td> <td> </td> <td> </td> </tr> <tr> <td>TIM-1/KIM-1/HAVCR</td> <td> </td> <td> </td> </tr> <tr> <td>TNF-α</td> <td><a href="/search?keywords=PRTA00" target="_parent">PRTA00</a></td> <td><a href="/search?keywords=DY510" target="_parent">DY510</a></td> </tr> <tr> <td>TWEAK/TNFSF12</td> <td> </td> <td> </td> </tr> <tr> <td>VCAM-1/CD106</td> <td> </td> <td> </td> </tr> <tr> <td>VEGF</td> <td><a href="/search?keywords=RRV00" target="_parent">RRV00</a></td> <td><a href="/search?keywords=DY564" target="_parent">DY564</a></td> </tr> <tr> <td>WISP-1/CCN</td> <td> </td> <td> </td> </tr> </tbody> </table> </div> </div> <h3 class="subheader18 mt-1">Specifications</h3> <div class="ds_table summary_table"> <div 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Do not use past expiration date.</div> </div> <div class="ds_table_row"> <div class="ds_table_cell summary_table_name">Species</div> <div class="ds_table_cell summary_table_data">Rat</div> </div> </div> </div> </div> <div class="datasheet_section" id="product-datasheets"> <h2 id="ds_datasheets">Product Datasheets</h2> <div class="product_datasheets"> <span class="sds-message hide"> <p class="sds-label">You must select a language.</p> <span class="close_sds_message">x</span> </span> <div class="ds_document"> <a id="cfpdf" href="//resources.rndsystems.com/pdfs/datasheets/ary030.pdf?v=20241126" class="datasheets-link " target="_blank" rel="noreferrer nofollow">Product Datasheet</a> </div> <div class="ds_document"> <div class="ds_pdfData"><a class="datasheets-link" href="https://www.rndsystems.com/cofas/proteome-profiler-rat-xl-cytokine-array_ary030">COA</a> </div> </div> <div class="ds_document sds_link"> <a class="sds_non_cf datasheets-link non_cf_download_link" target="_blank" rel="noreferrer" data-path="//resources.rndsystems.com/pdfs/msds/ary030.pdf?v=20241126">SDS</a> </div> </div> </div> <div id="customer_also_purchased_block" class="loader" data-catalogId="ARY030"></div> <div id="ds_scientific_data" class="datasheet_section"> <div id="ds_data_examples"> <h2>Scientific Data</h2> <div id="data_examples"> <div class="row data_ex_row"> <a id="ds_image_0" class="pageAnchor"></a> <div class="data_ex_image_wrapper col-xs-12 col-sm-5 col-md-4"> <div class="data_ex_image"> <span class="data_ex_image_label"> N/A </span> <a class="ds-image overview-images data_ex_image_link" data-toggle="lightbox" data-gallery="overview-images-0" data-title="The Mouse XL Cytokine Array detects multiple cytokines, chemokines, growth factors and other soluble proteins in cell culture supernates." data-footer="The Mouse XL Cytokine Array detects multiple cytokines, chemokines, growth factors and other soluble proteins in cell culture supernates." title="Cat. No. - The Mouse XL Cytokine Array detects multiple cytokines, chemokines, growth factors and other soluble proteins in cell culture supernates." href="https://resources.rndsystems.com/images/datasheets/ary030_proteome-profiler-rat-xl-cytokine-array-5112020143855.png"> <img loading="lazy" src="https://resources.rndsystems.com/images/datasheets/ary030_proteome-profiler-rat-xl-cytokine-array-5112020143855.png" class="img-fluid" alt="The Mouse XL Cytokine Array detects multiple cytokines, chemokines, growth factors and other soluble proteins in cell culture supernates." title="The Mouse XL Cytokine Array detects multiple cytokines, chemokines, growth factors and other soluble proteins in cell culture supernates."> <span class="data_ex_image_larger">View Larger</span> </a> </div> </div> <div class="data_ex_description col-xs-12 col-sm-7 col-md-8"> <p> <span class="data_ex_description_title">The Mouse XL Cytokine Array detects multiple cytokines, chemokines, growth factors and other soluble proteins in cell culture supernates.</span> Cells were untreated or treated as indicated below. 500 µL of cell culture supernate was run on each array. Data shown are from a 10 minute exposure to X-ray film. Profiles of mean spot pixel density were created using a transmission-mode scanner and image analysis software. Figure 1A: NR8383 normal rat lung cells were left untreated or treated with 1 μg/mL LPS for 24 hours (500 μL of cell culture supernate, 5 minute exposure). </p> </div> </div> <div class="row data_ex_row"> <a id="ds_image_1" class="pageAnchor"></a> <div class="data_ex_image_wrapper col-xs-12 col-sm-5 col-md-4"> <div class="data_ex_image"> <span class="data_ex_image_label"> N/A </span> <a class="ds-image overview-images data_ex_image_link" data-toggle="lightbox" data-gallery="overview-images-1" data-title="The Mouse XL Cytokine Array detects multiple cytokines, chemokines, growth factors and other soluble proteins in cell culture supernates." data-footer="The Mouse XL Cytokine Array detects multiple cytokines, chemokines, growth factors and other soluble proteins in cell culture supernates." title="Cat. No. - The Mouse XL Cytokine Array detects multiple cytokines, chemokines, growth factors and other soluble proteins in cell culture supernates." href="https://resources.rndsystems.com/images/datasheets/ary030_proteome-profiler-rat-xl-cytokine-array-5112020143958.png"> <img loading="lazy" src="https://resources.rndsystems.com/images/datasheets/ary030_proteome-profiler-rat-xl-cytokine-array-5112020143958.png" class="img-fluid" alt="The Mouse XL Cytokine Array detects multiple cytokines, chemokines, growth factors and other soluble proteins in cell culture supernates." title="The Mouse XL Cytokine Array detects multiple cytokines, chemokines, growth factors and other soluble proteins in cell culture supernates."> <span class="data_ex_image_larger">View Larger</span> </a> </div> </div> <div class="data_ex_description col-xs-12 col-sm-7 col-md-8"> <p> <span class="data_ex_description_title">The Mouse XL Cytokine Array detects multiple cytokines, chemokines, growth factors and other soluble proteins in cell culture supernates.</span> Cells were untreated or treated as indicated below. 500 µL of cell culture supernate was run on each array. Data shown are from a 10 minute exposure to X-ray film. Profiles of mean spot pixel density were created using a transmission-mode scanner and image analysis software. Figure 1B: IEC-18 rat intestinal epithelial cells were left untreated or treated with 1 μg/mL LPS for 24 hours (500 μL of cell culture supernate, 5 minute exposure). </p> </div> </div> <div class="row data_ex_row"> <a id="ds_image_2" class="pageAnchor"></a> <div class="data_ex_image_wrapper col-xs-12 col-sm-5 col-md-4"> <div class="data_ex_image"> <span class="data_ex_image_label"> N/A </span> <a class="ds-image overview-images data_ex_image_link" data-toggle="lightbox" data-gallery="overview-images-2" data-title="The Mouse XL Cytokine Array detects multiple cytokines, chemokines, growth factors and other soluble proteins in cell culture supernates." data-footer="The Mouse XL Cytokine Array detects multiple cytokines, chemokines, growth factors and other soluble proteins in cell culture supernates." title="Cat. No. - The Mouse XL Cytokine Array detects multiple cytokines, chemokines, growth factors and other soluble proteins in cell culture supernates." href="https://resources.rndsystems.com/images/datasheets/ary030_proteome-profiler-rat-xl-cytokine-array-5112020144051.png"> <img loading="lazy" src="https://resources.rndsystems.com/images/datasheets/ary030_proteome-profiler-rat-xl-cytokine-array-5112020144051.png" class="img-fluid" alt="The Mouse XL Cytokine Array detects multiple cytokines, chemokines, growth factors and other soluble proteins in cell culture supernates." title="The Mouse XL Cytokine Array detects multiple cytokines, chemokines, growth factors and other soluble proteins in cell culture supernates."> <span class="data_ex_image_larger">View Larger</span> </a> </div> </div> <div class="data_ex_description col-xs-12 col-sm-7 col-md-8"> <p> <span class="data_ex_description_title">The Mouse XL Cytokine Array detects multiple cytokines, chemokines, growth factors and other soluble proteins in cell culture supernates.</span> Cells were untreated or treated as indicated below. 500 µL of cell culture supernate was run on each array. Data shown are from a 10 minute exposure to X-ray film. Profiles of mean spot pixel density were created using a transmission-mode scanner and image analysis software. Figure 2A: Lysates from IEC-18 rat intestinal epithelial cells were left untreated or treated with 100 ng/mL PMA for 24 hours (200 μg lysate, 5 minute exposure. </p> </div> </div> <div class="row data_ex_row"> <a id="ds_image_3" class="pageAnchor"></a> <div class="data_ex_image_wrapper col-xs-12 col-sm-5 col-md-4"> <div class="data_ex_image"> <span class="data_ex_image_label"> N/A </span> <a class="ds-image overview-images data_ex_image_link" data-toggle="lightbox" data-gallery="overview-images-3" data-title="The Mouse XL Cytokine Array detects multiple cytokines, chemokines, growth factors and other soluble proteins in cell culture supernates." data-footer="The Mouse XL Cytokine Array detects multiple cytokines, chemokines, growth factors and other soluble proteins in cell culture supernates." title="Cat. No. - The Mouse XL Cytokine Array detects multiple cytokines, chemokines, growth factors and other soluble proteins in cell culture supernates." href="https://resources.rndsystems.com/images/datasheets/ary030_proteome-profiler-rat-xl-cytokine-array-5112020144155.png"> <img loading="lazy" src="https://resources.rndsystems.com/images/datasheets/ary030_proteome-profiler-rat-xl-cytokine-array-5112020144155.png" class="img-fluid" alt="The Mouse XL Cytokine Array detects multiple cytokines, chemokines, growth factors and other soluble proteins in cell culture supernates." title="The Mouse XL Cytokine Array detects multiple cytokines, chemokines, growth factors and other soluble proteins in cell culture supernates."> <span class="data_ex_image_larger">View Larger</span> </a> </div> </div> <div class="data_ex_description col-xs-12 col-sm-7 col-md-8"> <p> <span class="data_ex_description_title">The Mouse XL Cytokine Array detects multiple cytokines, chemokines, growth factors and other soluble proteins in cell culture supernates.</span> Cells were untreated or treated as indicated below. 500 µL of cell culture supernate was run on each array. Data shown are from a 10 minute exposure to X-ray film. Profiles of mean spot pixel density were created using a transmission-mode scanner and image analysis software. Figure 2B: Lysates from NR8383 normal rat lung cells were left untreated or treated with 5 μg/mL zymosan for 24 hours (200 μg lysate, 5 minute exposure). </p> </div> </div> </div> </div> </div> </div>   <div class="tab_content tab_3" data-tab="3" data-tabname="product-citations" id="citations"> <a id="citations_section"></a> <h2><span class="citations">Citations for Proteome Profiler Rat XL Cytokine Array</h2> <div id="citation"> <a id="dsTabCitations"></a> <p> R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. </p> <p> <strong><span id="maxcitations">13</span> Citations: Showing <span id="showfrom">1</span> - <span id="showto">10</span> </strong> <br/><strong>Filter your results:</strong> </p> <div class="row"> <div class="col-sm-12"> <div class="citations_filters"> <p style="display:inline;"><b>Filter by:</b></p> <div class="select_wrapper filter_select"> <select id="selSpecies" title="Species"> <option value="All">All Species</option> <option class="citation_filterRadio" value="species" data-filter="Rat"> Rat </option> </select> </div> <input type="hidden" id="selAntibody" value="All"> <div class="select_wrapper filter_select"> <select id="selSampleType" title="Sample Types"> <option value="All">All Sample Types</option> <option class="citation_filterRadio" value="sampletype" data-filter="Cell Culture Supernates"> Cell Culture Supernates </option> <option class="citation_filterRadio" value="sampletype" data-filter="Cell culture supernate"> Cell culture supernate </option> <option class="citation_filterRadio" value="sampletype" data-filter="Complex Sample Type"> Complex Sample Type </option> <option class="citation_filterRadio" value="sampletype" data-filter="Serum"> Serum </option> <option class="citation_filterRadio" value="sampletype" data-filter="Tissue Culture Supernates"> Tissue Culture Supernates </option> <option class="citation_filterRadio" value="sampletype" data-filter="Tissue Homogenates"> Tissue Homogenates </option> </select> </div> </div> </div> </div> <div class="row"> <ol id="citations" class="col-xs-12" data-expandall="false" data-max-citations="13" data-max-show="10"> <li class="top-lined" data-species="Rat" data-application="" data-sampletype="Cell Culture Supernates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/38474123"> Early Impairment of Paracrine and Phenotypic Features in Resident Cardiac Mesenchymal Stromal Cells after Thoracic Radiotherapy </a> </span><br/> Authors: Picchio, V;Gaetani, R;Pagano, F;Derevyanchuk, Y;Pagliarosi, O;Floris, E;Cozzolino, C;Bernava, G;Bordin, A;Rocha, F;Pereira, ARS;Ministro, A;Pinto, AT;De Falco, E;Serino, G;Massai, D;Tamarat, R;Pesce, M;Santos, SCR;Messina, E;Chimenti, I;<br/> International journal of molecular sciences  2024-03-01 <br/> </li> <li class="top-lined" data-species="Rat" data-application="" data-sampletype="Cell Culture Supernates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/38266090"> Time-dependent effects of BRAF-V600E on cell cycling, metabolism, and function in engineered myocardium </a> </span><br/> Authors: Strash, N;DeLuca, S;Janer Carattini, GL;Chen, Y;Wu, T;Helfer, A;Scherba, J;Wang, I;Jain, M;Naseri, R;Bursac, N;<br/> Science advances  2024-01-26 <br/> </li> <li class="top-lined" data-species="Rat" data-application="" data-sampletype="Tissue Culture Supernates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/38069130"> CXCR2-Blocking Has Context-Sensitive Effects on Rat Glioblastoma Cell Line Outgrowth (S635) in an Organotypic Rat Brain Slice Culture Depending on Microglia-Depletion (PLX5622) and Dexamethasone Treatment </a> </span><br/> Authors: Falter, J;Lohmeier, A;Eberl, P;Stoerr, EM;Koskimäki, J;Falter, L;Rossmann, J;Mederer, T;Schmidt, NO;Proescholdt, M;<br/> International journal of molecular sciences  2023-11-27 <br/> </li> <li class="top-lined" data-species="Rat" data-application="" data-sampletype="Cell Culture Supernates"> <span class="ctitle"> <a target="_blank" rel="noreferrer nofollow" class="safe_link" href="//www.ncbi.nlm.nih.gov/pubmed/36674885"> The Application of Adipose Tissue-Derived Mesenchymal Stem Cells (ADMSCs) and a Twin-Herb Formula to the Rodent Wound Healing Model: Use Alone or Together? 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Pathways</span> <img class="pathway_image" loading="lazy" alt="IL-17 Family Signaling Pathways" src="//resources.rndsystems.com/images/Pathways/Thumbnails/il-17-signaling-pathways.png"> </a> </li> <li class="pathway_wrapper"> <a class="pathway_link" href="https://www.rndsystems.com/pathways/il2-signaling-biological-effects-different-immune-cell-types"> <span class="pathway_title">IL-2 Signaling and its Primary Biological Effects in Different Immune Cell Types</span> <img class="pathway_image" loading="lazy" alt="IL-2 Signaling and its Primary Biological Effects in Different Immune Cell Types" src="//resources.rndsystems.com/images/Pathways/Thumbnails/il-2-signaling-pathways-effects.png"> </a> </li> <li class="pathway_wrapper"> <a class="pathway_link" href="https://www.rndsystems.com/pathways/il2-signaling-pathways"> <span class="pathway_title">IL-2 Signaling Pathways</span> <img class="pathway_image" loading="lazy" alt="IL-2 Signaling Pathways" src="//resources.rndsystems.com/images/Pathways/Thumbnails/il-2-signaling-pathways.png"> </a> </li> <li class="pathway_wrapper"> <a class="pathway_link" href="https://www.rndsystems.com/pathways/il21-signaling-biological-effects-different-immune-cell-types"> <span class="pathway_title">IL-21 Signaling and its Primary Biological Effects in Different Immune Cell Types</span> <img class="pathway_image" loading="lazy" alt="IL-21 Signaling and its Primary Biological Effects in Different Immune Cell Types" src="//resources.rndsystems.com/images/Pathways/Thumbnails/il-21-signaling-pathways-effects.png"> </a> </li> <li class="pathway_wrapper"> <a class="pathway_link" href="https://www.rndsystems.com/pathways/il4-signaling-biological-effects-different-immune-cell-types"> <span class="pathway_title">IL-4 Signaling and its Primary Biological Effects in Different Immune Cell Types</span> <img class="pathway_image" loading="lazy" alt="IL-4 Signaling and its Primary Biological Effects in Different Immune Cell Types" src="//resources.rndsystems.com/images/Pathways/Thumbnails/il-4-signaling-pathways-effects.png"> </a> </li> <li class="pathway_wrapper"> <a class="pathway_link" href="https://www.rndsystems.com/pathways/il4-signaling-pathways"> <span class="pathway_title">IL-4 Signaling Pathways</span> <img class="pathway_image" loading="lazy" alt="IL-4 Signaling Pathways" src="//resources.rndsystems.com/images/Pathways/Thumbnails/il-4-signaling-pathways.png"> </a> </li> <li class="pathway_wrapper"> <a class="pathway_link" href="https://www.rndsystems.com/pathways/il9-signaling-biological-effects-different-immune-cell-types"> <span class="pathway_title">IL-9 Signaling and its Primary Biological Effects in Different Immune Cell Types</span> <img class="pathway_image" loading="lazy" alt="IL-9 Signaling and its Primary Biological Effects in Different Immune Cell Types" src="//resources.rndsystems.com/images/Pathways/Thumbnails/il-9-signaling-pathways-effects.png"> </a> </li> <li class="pathway_wrapper"> <a class="pathway_link" href="https://www.rndsystems.com/pathways/inflammasome-activation-pathways"> <span class="pathway_title">Inflammasome Activation Pathways</span> <img class="pathway_image" loading="lazy" alt="Inflammasome Activation Pathways" src="//resources.rndsystems.com/images/Pathways/Thumbnails/inflammasome-activation-pathways.png"> </a> </li> <li class="pathway_wrapper"> <a class="pathway_link" href="https://www.rndsystems.com/pathways/innate-lymphoid-cells-differentiation"> <span class="pathway_title">Innate Lymphoid Cells Differentiation</span> <img class="pathway_image" loading="lazy" alt="Innate Lymphoid Cells Differentiation" src="//resources.rndsystems.com/images/Pathways/Thumbnails/innate-lymphoid-cells-differentiation.jpg"> </a> </li> <li class="pathway_wrapper"> <a class="pathway_link" href="https://www.rndsystems.com/pathways/jak-stat-signaling-pathway"> <span class="pathway_title">Jak/STAT Signaling Pathway</span> <img class="pathway_image" loading="lazy" alt="Jak/STAT Signaling Pathway" src="//resources.rndsystems.com/images/Pathways/Thumbnails/jak-stat-signaling-pathways.png"> </a> </li> <li class="pathway_wrapper"> <a class="pathway_link" href="https://www.rndsystems.com/pathways/mesenchymal-stem-cells-lineage-specific-markers"> <span class="pathway_title">Mesenchymal Stem Cells & Lineage-specific Markers</span> <img class="pathway_image" loading="lazy" alt="Mesenchymal Stem Cells &amp; Lineage-specific Markers" src="//resources.rndsystems.com/images/Pathways/Thumbnails/mesenchymal-stem-cells.png"> </a> </li> <li class="pathway_wrapper"> <a class="pathway_link" href="https://www.rndsystems.com/pathways/mtor-signaling"> <span class="pathway_title">mTOR Signaling</span> <img class="pathway_image" loading="lazy" alt="mTOR Signaling" src="//resources.rndsystems.com/images/Pathways/Thumbnails/mtor-signaling.png"> </a> </li> <li class="pathway_wrapper"> <a class="pathway_link" href="https://www.rndsystems.com/pathways/neural-stem-cells-lineage-specific-markers"> <span class="pathway_title">Neural Stem Cells & Lineage-specific Markers</span> <img class="pathway_image" loading="lazy" alt="Neural Stem Cells &amp; Lineage-specific Markers" src="//resources.rndsystems.com/images/Pathways/Thumbnails/neural-stem-cells.png"> </a> </li> <li class="pathway_wrapper"> <a class="pathway_link" href="https://www.rndsystems.com/pathways/nod-like-receptor-signaling-pathway"> <span class="pathway_title">NOD-like Receptor Signaling Pathways</span> <img class="pathway_image" loading="lazy" alt="NOD-like Receptor Signaling Pathways" src="//resources.rndsystems.com/images/Pathways/Thumbnails/nod-like-receptors.png"> </a> </li> <li class="pathway_wrapper"> <a class="pathway_link" href="https://www.rndsystems.com/pathways/notch-signaling-pathway"> <span class="pathway_title">Notch Signaling Pathways</span> <img class="pathway_image" loading="lazy" alt="Notch Signaling Pathways" src="//resources.rndsystems.com/images/Pathways/Thumbnails/notch-signaling-pathways.png"> </a> </li> <li class="pathway_wrapper"> <a class="pathway_link" href="https://www.rndsystems.com/pathways/th1-differentiation"> <span class="pathway_title">Th1 Differentiation</span> <img class="pathway_image" loading="lazy" alt="Th1 Differentiation" src="//resources.rndsystems.com/images/Pathways/Thumbnails/th1-differentiation.png"> </a> </li> <li class="pathway_wrapper"> <a class="pathway_link" href="https://www.rndsystems.com/pathways/th17-differentiation"> <span class="pathway_title">Th17 Differentiation</span> <img class="pathway_image" loading="lazy" alt="Th17 Differentiation" src="//resources.rndsystems.com/images/Pathways/Thumbnails/th17-differentiation.png"> </a> </li> <li class="pathway_wrapper"> <a class="pathway_link" href="https://www.rndsystems.com/pathways/th2-differentiation"> <span class="pathway_title">Th2 Differentiation</span> <img class="pathway_image" loading="lazy" alt="Th2 Differentiation" src="//resources.rndsystems.com/images/Pathways/Thumbnails/th2-differentiation.png"> </a> </li> <li class="pathway_wrapper"> <a class="pathway_link" href="https://www.rndsystems.com/pathways/tnf-superfamily-human-ligand-receptor-interactions-associated-functions"> <span class="pathway_title">TNF Superfamily - Human Ligand-Receptor Interactions & their Associated Functions</span> <img class="pathway_image" loading="lazy" alt="TNF Superfamily - Human Ligand-Receptor Interactions &amp; their Associated Functions" src="//resources.rndsystems.com/images/Pathways/Thumbnails/tnf-superfamily.png"> </a> </li> <li class="pathway_wrapper"> <a class="pathway_link" href="https://www.rndsystems.com/pathways/toll-like-receptor-signaling-pathways"> <span class="pathway_title">Toll-Like receptor Signaling Pathways</span> <img class="pathway_image" loading="lazy" alt="Toll-Like receptor Signaling Pathways" src="//resources.rndsystems.com/images/Pathways/Thumbnails/toll-like-receptor.png"> </a> </li> <li class="pathway_wrapper"> <a class="pathway_link" href="https://www.rndsystems.com/pathways/vegf-vegf-r2-signaling-pathways"> <span class="pathway_title">VEGF - VEGF R2 Signaling Pathways</span> <img class="pathway_image" loading="lazy" alt="VEGF - VEGF R2 Signaling Pathways" src="//resources.rndsystems.com/images/Pathways/Thumbnails/vegf-vegf-r2-signaling-pathways.png"> </a> </li> </ul> </div> </div> </div>  <div class="widget"> <div class="widget_title">R&D Systems Guarantee</div> <div class="widget_content" id="guarantee_area"> <div class="row"> <div class="guarantee_left col-xs-6 col-sm-12 col-lg-6"> <a href="/guarantee"><img loading="lazy" class="guarantee_image" alt="Product Performance Pledge" src="//resources.rndsystems.com/images/site/rndguarantee.png"></a> </div> <div class="guarantee_right col-xs-6 col-sm-12 col-lg-6"> <p>We offer a 100% guarantee on all our products.</p> <a 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Proteome Profiler Rat XL Cytokine Array ARY030: R&D Systems