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Shanker</title> <meta name="description" content="Search results for: Kalakotla Shanker"> <meta name="keywords" content="Kalakotla Shanker"> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1, maximum-scale=1, user-scalable=no"> <meta charset="utf-8"> <link href="https://cdn.waset.org/favicon.ico" type="image/x-icon" rel="shortcut icon"> <link href="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/css/bootstrap.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/plugins/fontawesome/css/all.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/css/site.css?v=150220211555" rel="stylesheet"> </head> <body> <header> <div class="container"> <nav class="navbar navbar-expand-lg navbar-light"> <a class="navbar-brand" href="https://waset.org"> <img src="https://cdn.waset.org/static/images/wasetc.png" alt="Open Science Research Excellence" title="Open Science Research Excellence" /> </a> <button class="d-block d-lg-none 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action="https://publications.waset.org/abstracts/search"> <div id="custom-search-input"> <div class="input-group"> <i class="fas fa-search"></i> <input type="text" class="search-query" name="q" placeholder="Author, Title, Abstract, Keywords" value="Kalakotla Shanker"> <input type="submit" class="btn_search" value="Search"> </div> </div> </form> </div> </div> <div class="row mt-3"> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Commenced</strong> in January 2007</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Frequency:</strong> Monthly</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Edition:</strong> International</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Paper Count:</strong> 16</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: Kalakotla Shanker</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">16</span> In vivo Therapeutic Potential of Biologically Synthesized Silver Nanoparticles</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Kalakotla%20Shanker">Kalakotla Shanker</a>, <a href="https://publications.waset.org/abstracts/search?q=G.%20Krishna%20Mohan"> G. Krishna Mohan</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Nowadays, nanoparticles are being used in pharmacological studies for their exclusive properties such as small size, more surface area, biocompatibility and enhanced solubility. In view of this, the present study aimed to evaluate the antihyperglycemic potential of biologically synthesized silver nanoparticles (BSSNPs) and <em>Gymnema sylvestre</em> (<em>GS) </em>extract. The SEM and SEM analysis divulges that the BSSNPs were spherical in shape. EDAX spectrum exhibits peaks for the presence of silver, carbon, and oxygen atoms in the range of 1.0-3.1 keV. FT-IR reveals the binding properties of active bio-constituents responsible for capping and stabilizing BSSNPs. The results showed increased blood glucose, huge loss in body weight and downturn in plasma insulin. The <em>GS</em> extract (200 mg/kg, 400 mg/kg), BSSNPs (100 mg/kg, 200 mg/kg) and metformin 50 mg/kg were administered to the diabetic rats. BSSNPs at a dose level of 200 mg/kg (b.wt.p.o.) showed significant inhibition of (p<0.001) blood glucose levels as compared with <em>GS</em> extract treated group. The results obtained from study indicate that the BSSNP shows potent anti-diabetic activity. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=biological%20silver%20nanoparticles" title="biological silver nanoparticles">biological silver nanoparticles</a>, <a href="https://publications.waset.org/abstracts/search?q=G.%20sylvetre" title=" G. sylvetre"> G. sylvetre</a>, <a href="https://publications.waset.org/abstracts/search?q=gymnemic%20acid" title=" gymnemic acid"> gymnemic acid</a>, <a href="https://publications.waset.org/abstracts/search?q=streptozotocin" title=" streptozotocin"> streptozotocin</a>, <a href="https://publications.waset.org/abstracts/search?q=Wistar%20rats" title=" Wistar rats"> Wistar rats</a>, <a href="https://publications.waset.org/abstracts/search?q=antihyperglycemic%20activity" title=" antihyperglycemic activity"> antihyperglycemic activity</a>, <a href="https://publications.waset.org/abstracts/search?q=anti-hyperlipidemic%20activity" title=" anti-hyperlipidemic activity"> anti-hyperlipidemic activity</a> </p> <a href="https://publications.waset.org/abstracts/68131/in-vivo-therapeutic-potential-of-biologically-synthesized-silver-nanoparticles" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/68131.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">302</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">15</span> Assessment of Acute Oral Toxicity Studies and Anti Diabetic Activity of Herbal Mediated Nanomedicine</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Shanker%20Kalakotla">Shanker Kalakotla</a>, <a href="https://publications.waset.org/abstracts/search?q=Krishna%20Mohan%20Gottumukkala"> Krishna Mohan Gottumukkala</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Diabetes is a metabolic disorder characterized by hyperglycemia, carbohydrates, altered lipids and proteins metabolism. In recent research nanotechnology is a blazing field for the researchers; latterly there has been prodigious excitement in the nanomedicine and nano pharmacological area for the study of silver nanoparticles synthesis using natural products. Biological methods have been used to synthesize silver nanoparticles in presence of medicinally active antidiabetic plants, and this intention made us assess the biologically synthesized silver nanoparticles from the seed extract of Psoralea corylfolia using 1 mM silver nitrate solution. The synthesized herbal mediated silver nanoparticles (HMSNP’s) then subjected to various characterization techniques such as XRD, SEM, EDX, TEM, DLS, UV and FT-IR respectively. In current study, the silver nanoparticles tested for in-vitro anti-diabetic activity and possible toxic effects in healthy female albino mice by following OECD guidelines-425. Herbal mediated silver nanoparticles were successfully obtained from bioreduction of silver nitrate using Psoralea corylifolia plant extract. Silver nanoparticles have been appropriately characterized and confirmed using different types of equipment viz., UV-vis spectroscopy, XRD, FTIR, DLS, SEM and EDX analysis. From the behavioral observations of the study, the female albino mice did not show sedation, respiratory arrest, and convulsions. Test compounds did not cause any mortality at the dose level tested (i.e., 2000 mg/kg body weight) doses till the end of 14 days of observation and were considered safe. It may be concluded that LD50 of the HMSNPs was 2000mg/kg body weight. Since LD50 of the HMSNPs was 2000mg/kg body weight, so the preferred dose range for HMSNPs falls between the levels of 200 and 400 mg/kg. Further In-vivo pharmacological models and biochemical investigations will clearly elucidate the mechanism of action and will be helpful in projecting the currently synthesized silver nanoparticles as a therapeutic target in treating chronic ailments. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=herbal%20mediated%20silver%20nanoparticles" title="herbal mediated silver nanoparticles">herbal mediated silver nanoparticles</a>, <a href="https://publications.waset.org/abstracts/search?q=HMSNPs" title=" HMSNPs"> HMSNPs</a>, <a href="https://publications.waset.org/abstracts/search?q=toxicity%20of%20silver%20nanoparticles" title=" toxicity of silver nanoparticles"> toxicity of silver nanoparticles</a>, <a href="https://publications.waset.org/abstracts/search?q=PTP1B%20in-vitro%20anti-diabetic%20assay%20female%20albino%20mice" title=" PTP1B in-vitro anti-diabetic assay female albino mice"> PTP1B in-vitro anti-diabetic assay female albino mice</a>, <a href="https://publications.waset.org/abstracts/search?q=425%20OECD%20guidelines" title=" 425 OECD guidelines"> 425 OECD guidelines</a> </p> <a href="https://publications.waset.org/abstracts/52640/assessment-of-acute-oral-toxicity-studies-and-anti-diabetic-activity-of-herbal-mediated-nanomedicine" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/52640.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">273</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">14</span> Novel Uses of Discarded Work Rolls of Cold Rolling Mills in Hot Strip Mill of Tata Steel India</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Uday%20Shanker%20Goel">Uday Shanker Goel</a>, <a href="https://publications.waset.org/abstracts/search?q=Vinay%20Vasant%20Mahashabde"> Vinay Vasant Mahashabde</a>, <a href="https://publications.waset.org/abstracts/search?q=Biswajit%20Ghosh"> Biswajit Ghosh</a>, <a href="https://publications.waset.org/abstracts/search?q=Arvind%20Jha"> Arvind Jha</a>, <a href="https://publications.waset.org/abstracts/search?q=Amit%20Kumar"> Amit Kumar</a>, <a href="https://publications.waset.org/abstracts/search?q=Sanjay%20Kumar%20Patel"> Sanjay Kumar Patel</a>, <a href="https://publications.waset.org/abstracts/search?q=Uma%20Shanker%20Pattanaik"> Uma Shanker Pattanaik</a>, <a href="https://publications.waset.org/abstracts/search?q=Vinit%20Kumar%20Shah"> Vinit Kumar Shah</a>, <a href="https://publications.waset.org/abstracts/search?q=Chaitanya%20Bhanu"> Chaitanya Bhanu</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Pinch rolls of the Hot Mills must possess resistance to wear, thermal stability, high thermal conductivity and through hardness. Conventionally, pinch rolls have been procured either as new ones or refurbished ones. Discarded Work Rolls from the Cold Mill were taken and machined inhouse at Tata Steel to be used subsequently as the bottom pinch rolls of the Hot Mill. The hardness of the scrapped work rolls from CRM is close to 55HRC and the typical composition is ( C - 0.8% , Mn - 0.40 % , Si - 0.40% , Cr - 3.5% , Mo - 0.5% & V - 0.1% ).The Innovation was the use of a roll which would otherwise have been otherwise discarded as scrap. Also, the innovation helped in using the scrapped roll which had better wear and heat resistance. In a conventional Pinch roil (Hardness 50 HRC and typical chemistry - C - 10% , Mo+Co+V+Nb ~ 5 % ) , Pick-up is a condition whereby foreign material becomes adhered to the surface of the pinch roll during service. The foreign material is usually adhered metal from the actual product being rolled. The main attributes of the weld overlay rolls are wear resistance and crack resistance. However, the weld overlay roll has a strong tendency for strip pick-up particularly in the area of bead overlap. However, the greatest disadvantage is the depth of weld deposit, which is less than half of the usable shell thickness in most mills. Because of this, the stainless rolls require re-welding on a routine basis. By providing a significantly cheaper in house and more robust alternative of the existing bottom pinch rolls , this innovation results in significant lower worries for the roll shop. Pinch rolls now don't have to be sent outside Jamshedpur for refurbishment or for procuring new ones. Scrapped rolls from adjacent Cold Mill are procured and sent for machining to our Machine Shop inside Tata Steel works in Jamshedpur. This is far more convenient than the older methodology. The idea is also being deployed to the other hot mills of Tata Steel. Multiple campaigns have been tried out at both down coilers of Hot Strip with significantly lower wear. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=hot%20rolling%20flat" title="hot rolling flat">hot rolling flat</a>, <a href="https://publications.waset.org/abstracts/search?q=cold%20mill%20work%20roll" title=" cold mill work roll"> cold mill work roll</a>, <a href="https://publications.waset.org/abstracts/search?q=hot%20strip%20pinch%20roll" title=" hot strip pinch roll"> hot strip pinch roll</a>, <a href="https://publications.waset.org/abstracts/search?q=strip%20surface" title=" strip surface"> strip surface</a> </p> <a href="https://publications.waset.org/abstracts/166767/novel-uses-of-discarded-work-rolls-of-cold-rolling-mills-in-hot-strip-mill-of-tata-steel-india" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/166767.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">128</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">13</span> Synthesis and Characterization of Some Nano-Structured Metal Hexacyanoferrates Using Sapindus mukorossi, a Natural Surfactant</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Uma%20Shanker">Uma Shanker</a>, <a href="https://publications.waset.org/abstracts/search?q=Vidhisha%20Jassal"> Vidhisha Jassal</a> </p> <p class="card-text"><strong>Abstract:</strong></p> A novel green route was used to synthesize few metal hexacyanoferrates (FeHCF, NiHCF, CoHCF and CuHCF) nanoparticles using Sapindus mukorossias a natural surfactant and water as a solvent. The synthesized nanoparticles were characterized by Powder X-ray diffraction (PXRD), Scanning electron microscopy (SEM), Transmission electron microscopy (TEM), Fourier Transform Infrared Spectroscopy (FTIR) and Thermo gravimetric techniques. Trasmission electron microscopic images showed that synthesized MHCF nanoparticles exhibited cubic and spherical shapes with exceptionally small sizes ranging from 3nm - 186 nm. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=metal%20hexacyanoferrates" title="metal hexacyanoferrates">metal hexacyanoferrates</a>, <a href="https://publications.waset.org/abstracts/search?q=natural%20surfactant" title=" natural surfactant"> natural surfactant</a>, <a href="https://publications.waset.org/abstracts/search?q=Sapindus%20mukorossias" title=" Sapindus mukorossias"> Sapindus mukorossias</a>, <a href="https://publications.waset.org/abstracts/search?q=nanoparticles" title=" nanoparticles "> nanoparticles </a> </p> <a href="https://publications.waset.org/abstracts/17815/synthesis-and-characterization-of-some-nano-structured-metal-hexacyanoferrates-using-sapindus-mukorossi-a-natural-surfactant" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/17815.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">526</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">12</span> Effect of Viscous Dissipation on 3-D MHD Casson Flow in Presence of Chemical Reaction: A Numerical Study</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Bandari%20Shanker">Bandari Shanker</a>, <a href="https://publications.waset.org/abstracts/search?q=Alfunsa%20Prathiba"> Alfunsa Prathiba</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The influence of viscous dissipation on MHD Casson 3-D fluid flow in two perpendicular directions past a linearly stretching sheet in the presence of a chemical reaction is explored in this work. For exceptional circumstances, self-similar solutions are obtained and compared to the given data. The enhancement in the values Ecert number the temperature boundary layer increases. Further, the current findings are observed to be in great accord with the existing data. In both directions, non - dimensional velocities and stress distribution are achieved. The relevant data are graphed and explained quantitatively in relation to changes in the Casson fluid parameter as well as other fluid flow parameters. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=viscous%20dissipation" title="viscous dissipation">viscous dissipation</a>, <a href="https://publications.waset.org/abstracts/search?q=3-D%20Casson%20flow" title=" 3-D Casson flow"> 3-D Casson flow</a>, <a href="https://publications.waset.org/abstracts/search?q=chemical%20reaction" title=" chemical reaction"> chemical reaction</a>, <a href="https://publications.waset.org/abstracts/search?q=Ecert%20number" title=" Ecert number"> Ecert number</a> </p> <a href="https://publications.waset.org/abstracts/144926/effect-of-viscous-dissipation-on-3-d-mhd-casson-flow-in-presence-of-chemical-reaction-a-numerical-study" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/144926.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">193</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">11</span> Sensor Data Analysis for a Large Mining Major</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sudipto%20Shanker%20Dasgupta">Sudipto Shanker Dasgupta</a> </p> <p class="card-text"><strong>Abstract:</strong></p> One of the largest mining companies wanted to look at health analytics for their driverless trucks. These trucks were the key to their supply chain logistics. The automated trucks had multi-level sub-assemblies which would send out sensor information. The use case that was worked on was to capture the sensor signal from the truck subcomponents and analyze the health of the trucks from repair and replacement purview. Open source software was used to stream the data into a clustered Hadoop setup in Amazon Web Services cloud and Apache Spark SQL was used to analyze the data. All of this was achieved through a 10 node amazon 32 core, 64 GB RAM setup real-time analytics was achieved on ‘300 million records’. To check the scalability of the system, the cluster was increased to 100 node setup. This talk will highlight how Open Source software was used to achieve the above use case and the insights on the high data throughput on a cloud set up. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=streaming%20analytics" title="streaming analytics">streaming analytics</a>, <a href="https://publications.waset.org/abstracts/search?q=data%20science" title=" data science"> data science</a>, <a href="https://publications.waset.org/abstracts/search?q=big%20data" title=" big data"> big data</a>, <a href="https://publications.waset.org/abstracts/search?q=Hadoop" title=" Hadoop"> Hadoop</a>, <a href="https://publications.waset.org/abstracts/search?q=high%20throughput" title=" high throughput"> high throughput</a>, <a href="https://publications.waset.org/abstracts/search?q=sensor%20data" title=" sensor data"> sensor data</a> </p> <a href="https://publications.waset.org/abstracts/32352/sensor-data-analysis-for-a-large-mining-major" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/32352.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">404</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">10</span> Biogenic Synthesis of ZnO Nanoparticles Using Annona muricata Plant Leaf Extract and Its Anti-Cancer Efficacy</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Siva%20Chander%20Chabattula">Siva Chander Chabattula</a>, <a href="https://publications.waset.org/abstracts/search?q=Piyush%20Kumar%20Gupta"> Piyush Kumar Gupta</a>, <a href="https://publications.waset.org/abstracts/search?q=Debashis%20Chakraborty"> Debashis Chakraborty</a>, <a href="https://publications.waset.org/abstracts/search?q=Rama%20Shanker%20Verma"> Rama Shanker Verma</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Green nanoparticles have gotten a lot of attention because of their potential applications in tissue regeneration, bioimaging, wound healing, and cancer therapy. The physical and chemical methods to synthesize metal oxide nanoparticles have an environmental impact, necessitating the development of an environmentally friendly green strategy for nanoparticle synthesis. In this study, we used Annona muricata plant leaf extract to synthesize Zinc Oxide nanoparticles (Am-ZnO NPs), which were evaluated using UV/Visible spectroscopy, FTIR spectroscopy, X-Ray Diffraction, DLS, and Zeta potential. Nanoparticles had an optical absorbance of 355 nm and a net negative surface charge of ~ - 2.59 mV. Transmission Electron Microscope characterizes the Shape and size of the nanoparticles. The obtained Am-ZnO NPs are biocompatible and hemocompatible in nature. These nanoparticles caused an anti-cancer therapeutic effect in MIA PaCa2 and MOLT4 cancer cells by inducing oxidative stress, and a change in mitochondrial membrane potential leads to programmed cell death. Further, we observed a reduction in the size of lung cancer spheroids (act as tumor micro-environment) with doxorubicin as a positive control. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Biomaterials" title="Biomaterials">Biomaterials</a>, <a href="https://publications.waset.org/abstracts/search?q=nanoparticle" title="nanoparticle">nanoparticle</a>, <a href="https://publications.waset.org/abstracts/search?q=anticancer%20activity" title="anticancer activity">anticancer activity</a>, <a href="https://publications.waset.org/abstracts/search?q=ZnO%20nanoparticles" title="ZnO nanoparticles">ZnO nanoparticles</a> </p> <a href="https://publications.waset.org/abstracts/147874/biogenic-synthesis-of-zno-nanoparticles-using-annona-muricata-plant-leaf-extract-and-its-anti-cancer-efficacy" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/147874.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">204</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9</span> Photocatalytic Degradation of Toxic Phenols Using Zinc Oxide Doped Prussian Blue Nanocomposite</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Rachna">Rachna</a>, <a href="https://publications.waset.org/abstracts/search?q=Uma%20Shanker"> Uma Shanker</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Aromatic phenols, being priority pollutants, are found in various industrial effluents and seeking the attention of environmentalists worldwide, owing to their life-threatening effects. In the present study, the coupling of zinc oxide with Prussian blue was achieved involving co-precipitation synthesis process using Azadirachta indica plant extract. The fabricated nanocatalyst was employed for the sunlight mediated photodegradation of various phenols (Phenol, 3-Aminophenol, and 2,4-Dinitrophenol). Doping of zinc oxide with Prussian blue caused an increase in the surface area to value 80.109 m²g⁻¹ and also enhanced the semiconducting tendency of the nanocomposite with band gap energy 1.101 eV. The experiment was performed at different parameters of phenols concentration, catalyst amount, pH, time, and exposure of sunlight. The obtained results showed a lower elimination of 2,4-DNP (93%) than 3-AP (97%) and phenol (95%) owing to their molecular weight and basicity differences. In comparison to the starting material (zinc oxide and Prussian blue), nanocomposite was more capable in degrading the phenols and lowered the t1/2 value of phenol (4.405 h), 3-AP (4.04 h) and 2,4-DNP (4.68 h) to a greater extent. Effect of different foreign anions was also studied to check nanocomposite’s liability under natural conditions. The extent of charge recombination being the most limiting factor in the photodegradation of pollutants was determined through the photoluminescence. Sunlight active ZnO@FeHCF nanocomposite was proven to exhibit good catalytic ability up to 10 cycles. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=nanocomposite" title="nanocomposite">nanocomposite</a>, <a href="https://publications.waset.org/abstracts/search?q=phenols" title=" phenols"> phenols</a>, <a href="https://publications.waset.org/abstracts/search?q=photodegradation" title=" photodegradation"> photodegradation</a>, <a href="https://publications.waset.org/abstracts/search?q=sunlight" title=" sunlight"> sunlight</a>, <a href="https://publications.waset.org/abstracts/search?q=water" title=" water"> water</a> </p> <a href="https://publications.waset.org/abstracts/112289/photocatalytic-degradation-of-toxic-phenols-using-zinc-oxide-doped-prussian-blue-nanocomposite" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/112289.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">126</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">8</span> Effect of Shrinkage on Heat and Mass Transfer Parameters of Solar Dried Potato Samples of Variable Diameter</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Kshanaprava%20Dhalsamant">Kshanaprava Dhalsamant</a>, <a href="https://publications.waset.org/abstracts/search?q=Punyadarshini%20P.%20Tripathy"> Punyadarshini P. Tripathy</a>, <a href="https://publications.waset.org/abstracts/search?q=Shanker%20L.%20Shrivastava"> Shanker L. Shrivastava</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Potato is chosen as the food product for carrying out the natural convection mixed-mode solar drying experiments since they are easily available and globally consumed. The convective heat and mass transfer coefficients along with effective diffusivity were calculated considering both shrinkage and without shrinkage for the potato cylinders of different geometry (8, 10 and 13 mm diameters and a constant length of 50 mm). The convective heat transfer coefficient (hc) without considering shrinkage effect were 24.28, 18.69, 15.89 W/m2˚C and hc considering shrinkage effect were 37.81, 29.21, 25.72 W/m2˚C for 8, 10 and 13 mm diameter samples respectively. Similarly, the effective diffusivity (Deff) without considering shrinkage effect were 3.20×10-9, 4.82×10-9, 2.48×10-8 m2/s and Deff considering shrinkage effect were 1.68×10-9, 2.56×10-9, 1.34×10-8 m2/s for 8, 10 and 13 mm diameter samples respectively and the mass transfer coefficient (hm) without considering the shrinkage effect were 5.16×10-7, 2.93×10-7, 2.59×10-7 m/s and hm considering shrinkage effect were 3.71×10-7, 2.04×10-7, 1.80×10-7 m/s for 8, 10 and 13 mm diameter samples respectively. Increased values of hc were obtained by considering shrinkage effect in all diameter samples because shrinkage results in decreasing diameter with time achieving in enhanced rate of water loss. The average values of Deff determined without considering the shrinkage effect were found to be almost double that with shrinkage effect. The reduction in hm values is due to the fact that with increasing sample diameter, the exposed surface area per unit mass decreases, resulting in a slower moisture removal. It is worth noting that considering shrinkage effect led to overestimation of hc values in the range of 55.72-61.86% and neglecting the shrinkage effect in the mass transfer analysis, the values of Deff and hm are overestimated in the range of 85.02-90.27% and 39.11-45.11%, respectively, for the range of sample diameter investigated in the present study. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=shrinkage" title="shrinkage">shrinkage</a>, <a href="https://publications.waset.org/abstracts/search?q=convective%20heat%20transfer%20coefficient" title=" convective heat transfer coefficient"> convective heat transfer coefficient</a>, <a href="https://publications.waset.org/abstracts/search?q=effectivive%20diffusivity" title=" effectivive diffusivity"> effectivive diffusivity</a>, <a href="https://publications.waset.org/abstracts/search?q=convective%20mass%20transfer%20coefficient" title=" convective mass transfer coefficient"> convective mass transfer coefficient</a> </p> <a href="https://publications.waset.org/abstracts/83081/effect-of-shrinkage-on-heat-and-mass-transfer-parameters-of-solar-dried-potato-samples-of-variable-diameter" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/83081.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">258</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">7</span> Effect of Pretreatment on Quality Parameters of Natural Convection Mixed-Mode Solar Dried Potato</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Kshanaprava%20Dhalsamant">Kshanaprava Dhalsamant</a>, <a href="https://publications.waset.org/abstracts/search?q=Punyadarshini%20P.%20Tripathy"> Punyadarshini P. Tripathy</a>, <a href="https://publications.waset.org/abstracts/search?q=Shanker%20L.%20Shrivastava"> Shanker L. Shrivastava</a> </p> <p class="card-text"><strong>Abstract:</strong></p> With present high global population, the need for rising food usage by minimizing food wastage and investment is highly necessary to achieve food security. The purpose of this study is to enlighten the effect of pre-drying treatment on rehydration, color, texture, nanohardness, microstructure and surface morphology of solar dried potato samples dried in the mixed-mode solar dryer. Locally bought potatoes were cleaned and cut into cylindrical pieces and pretreated with sodium metabisulfite (0.5%) for 10 min before placing them in natural convection solar dryer designed and developed in Indian Institute of Technology Kharagpur, India. Advanced quality characteristics were studied using Atomic Force Microscope (AFM), Scanning Electron Microscopy (SEM) and nanoindentation method, along with color, texture and water activity. The rehydration indices of solar dried potatoes were significantly biased by pretreatment followed by rehydration temperature. A lower redness index (a*) with a higher value of yellowness index (b*), chroma (C*) and hue angle (h*) were obtained for pretreated samples. Also, the average nanohardness (H) of untreated samples exhibited substantial lower value (18.46%) compared to pretreated samples. Additionally, a creep displacement of 43.27 nm during 20 s dwell time under constant load of 200 <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=pretreatment" title="pretreatment">pretreatment</a>, <a href="https://publications.waset.org/abstracts/search?q=nanohardness" title=" nanohardness"> nanohardness</a>, <a href="https://publications.waset.org/abstracts/search?q=microstructure" title=" microstructure"> microstructure</a>, <a href="https://publications.waset.org/abstracts/search?q=surface%20morphology" title=" surface morphology"> surface morphology</a> </p> <a href="https://publications.waset.org/abstracts/83034/effect-of-pretreatment-on-quality-parameters-of-natural-convection-mixed-mode-solar-dried-potato" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/83034.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">165</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">6</span> Correlation Analysis between the Corporate Governance and Financial Performance of Banking Sectors Using Parameter Estimation</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Vishwa%20Nath%20Maurya">Vishwa Nath Maurya</a>, <a href="https://publications.waset.org/abstracts/search?q=Rama%20Shanker%20Sharma"> Rama Shanker Sharma</a>, <a href="https://publications.waset.org/abstracts/search?q=Saad%20Talib%20Hasson%20Aljebori"> Saad Talib Hasson Aljebori</a>, <a href="https://publications.waset.org/abstracts/search?q=Avadhesh%20Kumar%20Maurya"> Avadhesh Kumar Maurya</a>, <a href="https://publications.waset.org/abstracts/search?q=Diwinder%20Kaur%20Arora"> Diwinder Kaur Arora</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Present paper deals with problems of determining the relationship between the variables of corporate governance and financial performance of Islamic banks. Here, we dealt with the corporate governance in the banking sector, where increasing the importance of corporate governance, due to their special nature, as the bankruptcy of banks affects not only the relevant parties from customers, depositors and lenders, but also affect financial stability and then the economy as a whole. Through this paper we dealt to the specificity of governance in Islamic banks, which face double governance: Anglo-Saxon governance system and Islamic governance system. In addition, we focused our attention to measure the impact of corporate governance variables on financial performance through an empirical study on a sample of Islamic banks during the period 2005-2012 in the GCC region. Our present study implies that there is a very strong relationship between the variables of governance and financial performance of Islamic banks, where there is a positive relationship between return on assets and the composition of the Board of Directors, the size of the Board of Directors, the number of committees in the Council, as well as the number of members of the Sharia Supervisory Board, while it is clear that there is a negative relationship between return on assets and concentration ownership. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=correlation%20analysis" title="correlation analysis">correlation analysis</a>, <a href="https://publications.waset.org/abstracts/search?q=parametric%20estimation" title=" parametric estimation"> parametric estimation</a>, <a href="https://publications.waset.org/abstracts/search?q=corporate%20governance" title=" corporate governance"> corporate governance</a>, <a href="https://publications.waset.org/abstracts/search?q=financial%20performance" title=" financial performance"> financial performance</a>, <a href="https://publications.waset.org/abstracts/search?q=financial%20stability" title=" financial stability"> financial stability</a>, <a href="https://publications.waset.org/abstracts/search?q=conventional%20banks" title=" conventional banks"> conventional banks</a>, <a href="https://publications.waset.org/abstracts/search?q=bankruptcy" title=" bankruptcy"> bankruptcy</a>, <a href="https://publications.waset.org/abstracts/search?q=Islamic%20governance%20system" title=" Islamic governance system "> Islamic governance system </a> </p> <a href="https://publications.waset.org/abstracts/22632/correlation-analysis-between-the-corporate-governance-and-financial-performance-of-banking-sectors-using-parameter-estimation" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/22632.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">516</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">5</span> Concrete Mix Design Using Neural Network</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Rama%20Shanker">Rama Shanker</a>, <a href="https://publications.waset.org/abstracts/search?q=Anil%20Kumar%20Sachan"> Anil Kumar Sachan</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Basic ingredients of concrete are cement, fine aggregate, coarse aggregate and water. To produce a concrete of certain specific properties, optimum proportion of these ingredients are mixed. The important factors which govern the mix design are grade of concrete, type of cement and size, shape and grading of aggregates. Concrete mix design method is based on experimentally evolved empirical relationship between the factors in the choice of mix design. Basic draw backs of this method are that it does not produce desired strength, calculations are cumbersome and a number of tables are to be referred for arriving at trial mix proportion moreover, the variation in attainment of desired strength is uncertain below the target strength and may even fail. To solve this problem, a lot of cubes of standard grades were prepared and attained 28 days strength determined for different combination of cement, fine aggregate, coarse aggregate and water. An artificial neural network (ANN) was prepared using these data. The input of ANN were grade of concrete, type of cement, size, shape and grading of aggregates and output were proportions of various ingredients. With the help of these inputs and outputs, ANN was trained using feed forward back proportion model. Finally trained ANN was validated, it was seen that it gave the result with/ error of maximum 4 to 5%. Hence, specific type of concrete can be prepared from given material properties and proportions of these materials can be quickly evaluated using the proposed ANN. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=aggregate%20proportions" title="aggregate proportions">aggregate proportions</a>, <a href="https://publications.waset.org/abstracts/search?q=artificial%20neural%20network" title=" artificial neural network"> artificial neural network</a>, <a href="https://publications.waset.org/abstracts/search?q=concrete%20grade" title=" concrete grade"> concrete grade</a>, <a href="https://publications.waset.org/abstracts/search?q=concrete%20mix%20design" title=" concrete mix design"> concrete mix design</a> </p> <a href="https://publications.waset.org/abstracts/13191/concrete-mix-design-using-neural-network" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/13191.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">389</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">4</span> Impact of Stress on Physical-Mental Wellbeing of Working Women in India: Awareness and Acceptability</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Meera%20Shanker">Meera Shanker</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Excellent education and financial need have encouraged Indian women to go out and work in well-paid and high-status occupations. In the era of cutthroat competition, women are expected to work hard to produce the desired result; hence, workload and expectations haveincreased. At home, they are anticipated to take care of family members, children, and household work. Women are stretching themselves mechanically to remain in the job competition and try to give their best at home. Consequentially, they are under tremendous pressure, stressed, and having issues related to physical-mental wellness. Mental healthcare is often ignored and not accepted due to a lack of awareness and cultural barriers. These further compounds the problem, resulting in decreased productivity in economic terms and an increase in stress-related physical-mental ailments. The main objective of the study was to find out the impact of stress on the physical-mental wellbeing of working women in India, along with their awareness and acceptability related to mental health. Six hundred and one woman working at various levels took part in this study, responding to the items related to stress and physical-mental illness. Finally, 21 items were retained under four meaningful factors measuring stress dimensions along with 17 items with three factors measuring physical-mental wellbeing. Confirmatory Factor Analysis (CFA), path analysis, in Structural Equation Modeling (SEM), was used to get a relationship, validity of the instruments. The psychometric properties of items and Cronbach’s Alpha reliabilities calculated for the subscales were relatively acceptable. The subscale correlations, regression, and path analysis of stress dimensions with physical-mental illness were found to be positive, indicating the growing stress among working women in India, which is impacting their physical-mental health. Single item analysis revealed that 77 percent of women have never visited psychologists. However, 70 percent of working women were not ready to seek the help of a psychologist. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=working%20women" title="working women">working women</a>, <a href="https://publications.waset.org/abstracts/search?q=stress" title=" stress"> stress</a>, <a href="https://publications.waset.org/abstracts/search?q=physical-mental%20well-being" title=" physical-mental well-being"> physical-mental well-being</a>, <a href="https://publications.waset.org/abstracts/search?q=confirmatory%20factor%20analysis" title=" confirmatory factor analysis"> confirmatory factor analysis</a> </p> <a href="https://publications.waset.org/abstracts/142678/impact-of-stress-on-physical-mental-wellbeing-of-working-women-in-india-awareness-and-acceptability" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/142678.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">185</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3</span> The Implications of Instrumental Animal Protection for the Legal and Moral Status of Animals</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ankita%20Shanker">Ankita Shanker</a>, <a href="https://publications.waset.org/abstracts/search?q=Angus%20Nurse"> Angus Nurse</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The notion of animal rights is an emerging trend in various spaces, including judicial and societal discourse. But one of the key purposes of recognizing the fundamental rights of anyone is their de-objectification. Animals are a prime example of a group that has rights that are neither recognized nor protected in any meaningful way, and anything that purports differently fails to ameliorate this because it still objectifies animals. Animals are currently treated by law and society as commodities with primarily (though not exclusively) instrumental value to some other rights-holder, such as humans or nature. So most protections that are afforded to them are done so in furtherance of the interests that they allegedly further, be it social morality or environmental protection. Animal rights are thus often seen as an application or extension of the rights of humans or, more commonly, the rights of nature. What this means is that animal rights are not always protected or even recognized in their own regard, but as stemming from some other reason, or worse, instrumentally as means to some other ends. This has two identifiable effects from a legal perspective: animal rights are not seen as inherently justified and are not seen as inherently valuable. Which in turn means that there can be no fundamental protection of animal rights. In other words, judicial protection does not always entail protection of animal ‘rights’ qua animal rights, which is needed for any meaningful protections to be afforded to animals. But the effects of this legal paradigm do not end at the legal status of animals. Because this status, in turn, affects how persons and the societies of which they form part see animals as a part of the rights of others, such as humans or nature, or as valuable only insofar as they further these rights, as opposed to as individuals with inherent worth and value deserving of protection regardless of their instrumental usefulness to these other objectives. This does nothing to truly de-objectify animals. Because even though most people would agree that animals are not objects, they continue to treat them as such wherever it serves them. For individuals and society to resolve, this inconsistency between stance and actions is for them to believe that animals are more than objects on a psychological and societal level. In this paper, we examine the implications of this perception of animals and their rights on the legal protections afforded to them and on the minds of individuals and civil society. We also argue that a change in the legal and societal status of animals can be brought about only through judicial, psychological, and sociological acknowledgment that animals have inherent value and deserve protection on this basis. Animal rights derived in such a way would not need to place reliance on other justifications and would not be subject to subjugation to other rights should a conflict arise. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=animal%20rights%20law" title="animal rights law">animal rights law</a>, <a href="https://publications.waset.org/abstracts/search?q=animal%20protection%20laws" title=" animal protection laws"> animal protection laws</a>, <a href="https://publications.waset.org/abstracts/search?q=psycho-socio-legal%20studies" title=" psycho-socio-legal studies"> psycho-socio-legal studies</a>, <a href="https://publications.waset.org/abstracts/search?q=animal%20rights" title=" animal rights"> animal rights</a>, <a href="https://publications.waset.org/abstracts/search?q=human%20rights" title=" human rights"> human rights</a>, <a href="https://publications.waset.org/abstracts/search?q=rights%20of%20nature" title=" rights of nature"> rights of nature</a> </p> <a href="https://publications.waset.org/abstracts/165219/the-implications-of-instrumental-animal-protection-for-the-legal-and-moral-status-of-animals" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/165219.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">108</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2</span> The Mediation Impact of Demographic and Clinical Characteristics on the Relationship between Trunk Control and Quality of Life among the Sub-Acute Stroke Population: A Cross-Sectional Study</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Kumar%20Gular">Kumar Gular</a>, <a href="https://publications.waset.org/abstracts/search?q=Viswanathan%20S."> Viswanathan S.</a>, <a href="https://publications.waset.org/abstracts/search?q=Mastour%20Saeed%20Alshahrani"> Mastour Saeed Alshahrani</a>, <a href="https://publications.waset.org/abstracts/search?q=Ravi%20Shankar%20Reddy"> Ravi Shankar Reddy</a>, <a href="https://publications.waset.org/abstracts/search?q=Jaya%20Shanker%20Tedla"> Jaya Shanker Tedla</a>, <a href="https://publications.waset.org/abstracts/search?q=Snehil%20Dixit"> Snehil Dixit</a>, <a href="https://publications.waset.org/abstracts/search?q=Ajay%20Prasad%20Gautam"> Ajay Prasad Gautam</a>, <a href="https://publications.waset.org/abstracts/search?q=Venkata%20Nagaraj%20Kakaraparthi"> Venkata Nagaraj Kakaraparthi</a>, <a href="https://publications.waset.org/abstracts/search?q=Devika%20Rani%20Sangadala"> Devika Rani Sangadala</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Despite trunk control’s significant contribution to improving various functional activity components, the independent effect of trunk performance on quality of life is yet to be estimated in stroke survivors. Ascertaining the correlation between trunk control and self-reported quality of life while evaluating the effect of demographic and clinical characteristics on their relationship will guide concerned healthcare professionals in designing ideal rehabilitation protocols during the late sub-acute stroke stage of recovery. The aims of the present research were to (1) investigate the associations of trunk performance with self-rated quality of life and (2) evaluate if age, body mass index (BMI), and clinical characteristics mediate the relationship between trunk motor performance and perceived quality of life in the sub-acute stroke population. Methods: Trunk motor functions and quality of life among the late sub-acute stroke population aged 57.53 ± 6.42 years were evaluated through the trunk Impairment Scale (TIS) and Stroke specific quality of life (SSQOL) questionnaire, respectively. Pearson correlation coefficients and mediation analysis were performed to elucidate the relationship of trunk motor function with quality of life and determine the mediation impact of demographic and clinical characteristics on their association, respectively. Results: The current study observed significant correlations between trunk motor functions (TIS) and quality of life (SSQOL) with r=0.68 (p<0.001). Age, BMI, and type of stroke were detected as potential mediating factors in the association between trunk performance and quality of life. Conclusion: Validated associations between trunk motor functions and perceived quality of life among the late sub-acute stroke population emphasize the importance of comprehensive evaluation of trunk control. Rehabilitation specialists should focus on appropriate strategies to enhance trunk performance anticipating the potential effects of age, BMI, and type of stroke to improve health-related quality of life in stroke survivors. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=sub-acute%20stroke" title="sub-acute stroke">sub-acute stroke</a>, <a href="https://publications.waset.org/abstracts/search?q=quality%20of%20life" title=" quality of life"> quality of life</a>, <a href="https://publications.waset.org/abstracts/search?q=functional%20independence" title=" functional independence"> functional independence</a>, <a href="https://publications.waset.org/abstracts/search?q=trunk%20control" title=" trunk control"> trunk control</a> </p> <a href="https://publications.waset.org/abstracts/166149/the-mediation-impact-of-demographic-and-clinical-characteristics-on-the-relationship-between-trunk-control-and-quality-of-life-among-the-sub-acute-stroke-population-a-cross-sectional-study" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/166149.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">78</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1</span> Application of Mesenchymal Stem Cells in Diabetic Therapy</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=K.%20J.%20Keerthi">K. J. Keerthi</a>, <a href="https://publications.waset.org/abstracts/search?q=Vasundhara%20Kamineni"> Vasundhara Kamineni</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Ravi%20Shanker"> A. Ravi Shanker</a>, <a href="https://publications.waset.org/abstracts/search?q=T.%20Rammurthy"> T. Rammurthy</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Vijaya%20Lakshmi"> A. Vijaya Lakshmi</a>, <a href="https://publications.waset.org/abstracts/search?q=Q.%20Hasan"> Q. Hasan </a> </p> <p class="card-text"><strong>Abstract:</strong></p> Pancreatic β-cells are the predominant insulin-producing cell types within the Islets of Langerhans and insulin is the primary hormone which regulates carbohydrate and fat metabolism. Apoptosis of β-cells or insufficient insulin production leads to Diabetes Mellitus (DM). Current therapy for diabetes includes either medical management or insulin replacement and regular monitoring. Replacement of β- cells is an attractive treatment option for both Type-1 and Type-2 DM in view of the recent paper which indicates that β-cells apoptosis is the common underlying cause for both the Types of DM. With the development of Edmonton protocol, pancreatic β-cells allo-transplantation became possible, but this is still not considered as standard of care due to subsequent requirement of lifelong immunosuppression and the scarcity of suitable healthy organs to retrieve pancreatic β-cell. Fetal pancreatic cells from abortuses were developed as a possible therapeutic option for Diabetes, however, this posed several ethical issues. Hence, in the present study Mesenchymal stem cells (MSCs) were differentiated into insulin producing cells which were isolated from Human Umbilical cord (HUC) tissue. MSCs have already made their mark in the growing field of regenerative medicine, and their therapeutic worth has already been validated for a number of conditions. HUC samples were collected with prior informed consent as approved by the Institutional ethical committee. HUC (n=26) were processed using a combination of both mechanical and enzymatic (collagenase-II, 100 U/ml, Gibco ) methods to obtain MSCs which were cultured in-vitro in L-DMEM (Low glucose Dulbecco's Modified Eagle's Medium, Sigma, 4.5 mM glucose/L), 10% FBS in 5% CO2 incubator at 37°C. After reaching 80-90% confluency, MSCs were characterized with Flowcytometry and Immunocytochemistry for specific cell surface antigens. Cells expressed CD90+, CD73+, CD105+, CD34-, CD45-, HLA-DR-/Low and Vimentin+. These cells were differentiated to β-cells by using H-DMEM (High glucose Dulbecco's Modified Eagle's Medium,25 mM glucose/L, Gibco), β-Mercaptoethanol (0.1mM, Hi-Media), basic Fibroblast growth factor (10 µg /L,Gibco), and Nicotinamide (10 mmol/L, Hi-Media). Pancreatic β-cells were confirmed by positive Dithizone staining and were found to be functionally active as they released 8 IU/ml insulin on glucose stimulation. Isolating MSCs from usually discarded, abundantly available HUC tissue, expanding and differentiating to β-cells may be the most feasible cell therapy option for the millions of people suffering from DM globally. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=diabetes%20mellitus" title="diabetes mellitus">diabetes mellitus</a>, <a href="https://publications.waset.org/abstracts/search?q=human%20umbilical%20cord" title=" human umbilical cord"> human umbilical cord</a>, <a href="https://publications.waset.org/abstracts/search?q=mesenchymal%20stem%20cells" title=" mesenchymal stem cells"> mesenchymal stem cells</a>, <a href="https://publications.waset.org/abstracts/search?q=differentiation" title=" differentiation"> differentiation</a> </p> <a href="https://publications.waset.org/abstracts/62087/application-of-mesenchymal-stem-cells-in-diabetic-therapy" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/62087.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">259</span> </span> </div> </div> </div> </main> <footer> <div id="infolinks" class="pt-3 pb-2"> <div class="container"> <div style="background-color:#f5f5f5;" class="p-3"> <div class="row"> <div class="col-md-2"> <ul class="list-unstyled"> About <li><a href="https://waset.org/page/support">About Us</a></li> <li><a href="https://waset.org/page/support#legal-information">Legal</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/WASET-16th-foundational-anniversary.pdf">WASET celebrates its 16th foundational anniversary</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Account <li><a href="https://waset.org/profile">My Account</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Explore <li><a href="https://waset.org/disciplines">Disciplines</a></li> <li><a href="https://waset.org/conferences">Conferences</a></li> <li><a href="https://waset.org/conference-programs">Conference Program</a></li> <li><a href="https://waset.org/committees">Committees</a></li> <li><a href="https://publications.waset.org">Publications</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Research <li><a href="https://publications.waset.org/abstracts">Abstracts</a></li> <li><a href="https://publications.waset.org">Periodicals</a></li> <li><a href="https://publications.waset.org/archive">Archive</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Open Science <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Science-Philosophy.pdf">Open Science Philosophy</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Science-Award.pdf">Open Science Award</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Society-Open-Science-and-Open-Innovation.pdf">Open Innovation</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Postdoctoral-Fellowship-Award.pdf">Postdoctoral Fellowship Award</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Scholarly-Research-Review.pdf">Scholarly Research Review</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Support <li><a href="https://waset.org/page/support">Support</a></li> <li><a href="https://waset.org/profile/messages/create">Contact Us</a></li> <li><a href="https://waset.org/profile/messages/create">Report Abuse</a></li> </ul> </div> </div> </div> </div> </div> <div class="container text-center"> <hr style="margin-top:0;margin-bottom:.3rem;"> <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank" class="text-muted small">Creative Commons Attribution 4.0 International License</a> <div id="copy" class="mt-2">© 2024 World Academy of Science, Engineering and Technology</div> </div> </footer> <a href="javascript:" id="return-to-top"><i class="fas fa-arrow-up"></i></a> <div class="modal" id="modal-template"> <div class="modal-dialog"> <div class="modal-content"> <div class="row m-0 mt-1"> <div class="col-md-12"> <button type="button" class="close" data-dismiss="modal" aria-label="Close"><span aria-hidden="true">×</span></button> </div> </div> <div class="modal-body"></div> </div> </div> </div> <script src="https://cdn.waset.org/static/plugins/jquery-3.3.1.min.js"></script> <script src="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/js/bootstrap.bundle.min.js"></script> <script src="https://cdn.waset.org/static/js/site.js?v=150220211556"></script> <script> jQuery(document).ready(function() { /*jQuery.get("https://publications.waset.org/xhr/user-menu", function (response) { jQuery('#mainNavMenu').append(response); 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