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href="http://blogs.dnalc.org/2012/02/06/tumor-treatment-whether-to-shrink-or-not-to-shrink/"><img width="72" height="72" src="http://blogs.dnalc.org/wp-content/uploads/2012/02/angio.jpg" class="attachment-post-thumbnail" alt="angio" /></a> <h2 class="title"><a href="http://blogs.dnalc.org/2012/02/06/tumor-treatment-whether-to-shrink-or-not-to-shrink/" rel="bookmark" title="Permanent Link: Tumor Treatment: Whether to Shrink or Not to Shrink">Tumor Treatment: Whether to Shrink or Not to Shrink</a></h2> <div class="post-date"> <p class="day">Feb 6th</p> </div> <div class="post-info clear-block with-thumbs"> <p class="author alignleft">Posted by <a href="http://blogs.dnalc.org/author/nash/" title="Posts by Bruce Nash ">Bruce Nash</a> in <a href="http://blogs.dnalc.org/category/sitetopics/insidecancer/">Inside Cancer</a> </p> <p class="comments alignright"><a href="http://blogs.dnalc.org/2012/02/06/tumor-treatment-whether-to-shrink-or-not-to-shrink/#comments" class="no comments">No comments</a></p> </div> <div class="post-content clear-block"> <p>Just like normal tissue, tumors need blood vessels to grow. Because of this, drugs that stop angiogenesis, or the formation of new blood vessels, are one important approach to treating cancers. These angiogenesis inhibitors stop tumor growth by starving them of oxygen and nutrients, usually by interfering with signals from the tumor cells that promote blood vessel formation in the surrounding tissue. Angiog<a href="http://blogs.dnalc.org/wp-content/uploads/2012/02/angio.jpg"></a>enesis inhibitors have been shown to be effective in the treatment of several cancer types, but the results aren鈥檛 always as expected. Several recent studies show how complicated this can be. For instance, FDA approval of the drug <a class="more-link" href="http://blogs.dnalc.org/2012/02/06/tumor-treatment-whether-to-shrink-or-not-to-shrink/">More ></a></p> </div> <div class="post-tags"> <a href="http://blogs.dnalc.org/tag/angiogenesis/" rel="tag" title="angiogenesis (1 topics)">angiogenesis</a>, <a href="http://blogs.dnalc.org/tag/biology/" rel="tag" title="biology (4 topics)">biology</a>, <a href="http://blogs.dnalc.org/tag/blood-vessels/" rel="tag" title="blood vessels (1 topics)">blood vessels</a>, <a href="http://blogs.dnalc.org/tag/breast/" rel="tag" title="breast (1 topics)">breast</a>, <a href="http://blogs.dnalc.org/tag/cancer/" rel="tag" title="Cancer (25 topics)">Cancer</a>, <a href="http://blogs.dnalc.org/tag/drugs/" rel="tag" title="drugs (4 topics)">drugs</a> </div> </div> <!-- /post --> <!-- post --> <div id="post-1493" class="hentry post post-2 even alt author-mckechni category-dnafromthebeginning post_tag-bacteria post_tag-biology post_tag-cockroach post_tag-medicine post_tag-microbes clear-block"> <a class="post-thumb size-post-thumbnail alignleft" href="http://blogs.dnalc.org/2010/09/22/cockroach-brains-as-medicine/"><img width="100" height="100" src="http://blogs.dnalc.org/wp-content/uploads/2010/09/cockroach-150x150-100x100.jpg" class="attachment-post-thumbnail wp-post-image" alt="cockroach-150x150" /></a> <h2 class="title"><a href="http://blogs.dnalc.org/2010/09/22/cockroach-brains-as-medicine/" rel="bookmark" title="Permanent Link: Cockroach Brains as Medicine">Cockroach Brains as Medicine</a></h2> <div class="post-date"> <p class="day">Sep 22nd</p> </div> <div class="post-info clear-block with-thumbs"> <p class="author alignleft">Posted by <a href="http://blogs.dnalc.org/author/mckechni/" title="Posts by Erin McKechnie ">Erin McKechnie</a> in <a href="http://blogs.dnalc.org/category/sitetopics/dnafromthebeginning/">DNA From The Beginning</a> </p> <p class="comments alignright"><a href="http://blogs.dnalc.org/2010/09/22/cockroach-brains-as-medicine/#comments" class="no comments">No comments</a></p> </div> <div class="post-content clear-block"> <p><a href="http://blogs.dnalc.org/wp-content/uploads/2010/09/cockroach-150x150.jpg"></a>Each day your body works to defend you against invaders.聽 Harmful bacteria, viruses, and fungi can enter your system and cause diseases.聽 In addition to relying on your immune system, it is helpful to avoid contact with germs by thoroughly washing your hands and keeping your environment clean.</p> <p>How is it possible that some organisms have the ability to survive in some of the dirtiest places on earth?聽 What survival mechanisms do they have that differ from ours?</p> <p>Scientists ground up the brains and other nerve tissues from two species of insects, the American cockroach and the desert locust.聽 Material extracted from <a class="more-link" href="http://blogs.dnalc.org/2010/09/22/cockroach-brains-as-medicine/">More ></a></p> </div> <div class="post-tags"> <a href="http://blogs.dnalc.org/tag/bacteria/" rel="tag" title="bacteria (3 topics)">bacteria</a>, <a href="http://blogs.dnalc.org/tag/biology/" rel="tag" title="biology (4 topics)">biology</a>, <a href="http://blogs.dnalc.org/tag/cockroach/" rel="tag" title="cockroach (1 topics)">cockroach</a>, <a href="http://blogs.dnalc.org/tag/medicine/" rel="tag" title="medicine (6 topics)">medicine</a>, <a href="http://blogs.dnalc.org/tag/microbes/" rel="tag" title="microbes (1 topics)">microbes</a> </div> </div> <!-- /post --> <!-- post --> <div id="post-655" class="hentry post post-3 odd author-connolly category-g2conline post_tag-biology post_tag-genetics post_tag-genomics post_tag-imaging post_tag-neuroimaging post_tag-psychology post_tag-psychosis post_tag-schizophrenia clear-block"> <a class="post-thumb size-post-thumbnail alignleft" href="http://blogs.dnalc.org/2009/05/12/psychosis-new-study-links-gene-variant-to-brain-structures/"><img width="100" height="100" src="http://blogs.dnalc.org/wp-content/uploads/2009/05/g2cblog_psychosis_thumb-100x100.jpg" class="attachment-post-thumbnail wp-post-image" alt="g2cblog_psychosis_thumb" /></a> <h2 class="title"><a href="http://blogs.dnalc.org/2009/05/12/psychosis-new-study-links-gene-variant-to-brain-structures/" rel="bookmark" title="Permanent Link: Psychosis – New Study Links Gene Variant to Brain Structures">Psychosis – New Study Links Gene Variant to Brain Structures</a></h2> <div class="post-date"> <p class="day">May 12th</p> </div> <div class="post-info clear-block with-thumbs"> <p class="author alignleft">Posted by <a href="http://blogs.dnalc.org/author/connolly/" title="Posts by connolly ">connolly</a> in <a href="http://blogs.dnalc.org/category/sitetopics/g2conline/">G2C Online</a> </p> <p class="comments alignright"><a href="http://blogs.dnalc.org/2009/05/12/psychosis-new-study-links-gene-variant-to-brain-structures/#comments" class="no comments">No comments</a></p> </div> <div class="post-content clear-block"> <p><a href="http://blogs.dnalc.org/wp-content/uploads/2009/05/g2cblog_psychosis_thumb.jpg"></a>A <a title="Esslinger, Walter et al. Psychosis" href="http://www.sciencemag.org/cgi/content/abstract/324/5927/605" target="_blank">study published in last week’s <em>Science </em>magazine</a> shows how genomic science and neuroimaging can be combined to deliver insights into cognitive disorders. As well as providing an intriguing look into the neurobiology of psychosis, the study reflects a growing trend toward inter-disciplinary research in the neurosciences,</p> <p><strong>What did the study show? </strong></p> <p>Psychosis is a disordered cognitive state that can include disorganized thoughts, delusions, or hallucinations. It is a common symptom of schizophrenia and has been linked to a number of brain areas, including the the dorsolateral <a title="G2C Online - Prefronal Cortex" href="http://www.g2conline.org/1251" target="_blank">prefrontal cortex</a> (DLPFC) and the <a title="G2C Online - Hippocampus" href="http://www.g2conline.org/1164" target="_self">hippocampus</a>. Schizophrenia is also strongly associated with a<a title="G2C Online - Schizophrneia Genes" href="http://www.g2conline.org/1243" target="_blank"> number of genes</a>, and <a class="more-link" href="http://blogs.dnalc.org/2009/05/12/psychosis-new-study-links-gene-variant-to-brain-structures/">More ></a></p> </div> <div class="post-tags"> <a href="http://blogs.dnalc.org/tag/biology/" rel="tag" title="biology (4 topics)">biology</a>, <a href="http://blogs.dnalc.org/tag/genetics/" rel="tag" title="genetics (12 topics)">genetics</a>, <a href="http://blogs.dnalc.org/tag/genomics/" rel="tag" title="genomics (5 topics)">genomics</a>, <a href="http://blogs.dnalc.org/tag/imaging/" rel="tag" title="imaging (2 topics)">imaging</a>, <a href="http://blogs.dnalc.org/tag/neuroimaging/" rel="tag" title="neuroimaging (3 topics)">neuroimaging</a>, <a href="http://blogs.dnalc.org/tag/psychology/" rel="tag" title="psychology (3 topics)">psychology</a>, <a href="http://blogs.dnalc.org/tag/psychosis/" rel="tag" title="psychosis (1 topics)">psychosis</a>, <a href="http://blogs.dnalc.org/tag/schizophrenia/" rel="tag" title="schizophrenia (8 topics)">schizophrenia</a> </div> </div> <!-- /post --> <!-- post --> <div id="post-656" class="hentry post post-4 even alt author-connolly category-g2conline post_tag-biology post_tag-brain post_tag-fmri post_tag-functional-magnetic-resonance-imaging post_tag-neuroimaging post_tag-posttraumatic-stress-disorder post_tag-psychology post_tag-ptsd clear-block"> <a class="post-thumb size-post-thumbnail alignleft" href="http://blogs.dnalc.org/2009/04/18/can-we-diagnose-ptsd-with-brain-scans/"><img width="100" height="100" src="http://blogs.dnalc.org/wp-content/uploads/2009/04/g2cblog_ptsd_thumb-100x100.jpg" class="attachment-post-thumbnail wp-post-image" alt="g2cblog_ptsd_thumb" /></a> <h2 class="title"><a href="http://blogs.dnalc.org/2009/04/18/can-we-diagnose-ptsd-with-brain-scans/" rel="bookmark" title="Permanent Link: Can We Diagnose PTSD with Brain Scans?">Can We Diagnose PTSD with Brain Scans?</a></h2> <div class="post-date"> <p class="day">Apr 18th</p> </div> <div class="post-info clear-block with-thumbs"> <p class="author alignleft">Posted by <a href="http://blogs.dnalc.org/author/connolly/" title="Posts by connolly ">connolly</a> in <a href="http://blogs.dnalc.org/category/sitetopics/g2conline/">G2C Online</a> </p> <p class="comments alignright"><a href="http://blogs.dnalc.org/2009/04/18/can-we-diagnose-ptsd-with-brain-scans/#comments" class="no comments">No comments</a></p> </div> <div class="post-content clear-block"> <p><a href="http://blogs.dnalc.org/wp-content/uploads/2009/04/g2cblog_ptsd_thumb.jpg"></a>Duke University’s Rajendra Morey was in the news this week following a presentation at the World Psychiatric Association Congress in Italy. Dr Morey’s group recently <a title="Morey et al. 2008" href="http://www.ncbi.nlm.nih.gov/pubmed/19091328?log$=activity" target="_blank">published a paper</a> equating symptoms of post posttraumatic stress disorder (PTSD) with “markedly different neural activity”. Dr. Morey raised the possibility of using brain scans to diagnose PTSD, thereby catapulting herself into the science pages of <a title="Forbes PTSD" href="http://www.forbes.com/feeds/hscout/2009/04/03/hscout625693.html" target="_blank">Forbes</a>, <a title="Reuters PTSD" href="http://uk.reuters.com/article/healthNewsMolt/idUKTRE53200T20090403" target="_blank">Reuters</a> <em>et al</em>. She joins a lengthy list of researchers that have whetted our appetite with tantalizing suggestions about the predictive power of neuroimaging. Sadly, the list of those who have followed through on this promise is not quite so <a class="more-link" href="http://blogs.dnalc.org/2009/04/18/can-we-diagnose-ptsd-with-brain-scans/">More ></a></p> </div> <div class="post-tags"> <a href="http://blogs.dnalc.org/tag/biology/" rel="tag" title="biology (4 topics)">biology</a>, <a href="http://blogs.dnalc.org/tag/brain/" rel="tag" title="brain (19 topics)">brain</a>, <a href="http://blogs.dnalc.org/tag/fmri/" rel="tag" title="fmri (1 topics)">fmri</a>, <a href="http://blogs.dnalc.org/tag/functional-magnetic-resonance-imaging/" rel="tag" title="functional magnetic resonance imaging (1 topics)">functional magnetic resonance imaging</a>, <a href="http://blogs.dnalc.org/tag/neuroimaging/" rel="tag" title="neuroimaging (3 topics)">neuroimaging</a>, <a href="http://blogs.dnalc.org/tag/posttraumatic-stress-disorder/" rel="tag" title="posttraumatic stress disorder (1 topics)">posttraumatic stress disorder</a>, <a href="http://blogs.dnalc.org/tag/psychology/" rel="tag" title="psychology (3 topics)">psychology</a>, <a href="http://blogs.dnalc.org/tag/ptsd/" rel="tag" title="ptsd (1 topics)">ptsd</a> </div> </div> <!-- /post --> </div> </div> <!-- /primary content --> <div id="sidebar"> <ul class="blocks"> <li class="block"><div class="block-widget_search clear-block" id="instance-search-3"> <!-- search form --> <div class="search-form"> <form method="get" id="searchform" action="http://blogs.dnalc.org/" class="clear-block"> <fieldset> <div id="searchfield"> <input type="text" name="s" id="searchbox" class="text clearField" value="Search" /> </div> <input type="submit" value="" class="submit" /> </fieldset> </form> </div> <!-- /search form --> </div></li><li class="block"><div class="block-sidebar_tabs clear-block" id="instance-sidebartabswidget-3"> <!-- tabbed content --> <div class="tabbed-content sidebar-tabs clear-block" id="sidebartabswidget-3"> <!-- tab navigation (items must be in reverse 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class="box-top-left"><div class="box-top-right"></div></div> <div class="box-main"> <div class="box-content"> <ul class="menuList recentcomm"> <li class="clear-block"><a title="Posted in: DNA DAY 2010: What, me worry about my DNA?" class="fadeThis" href="http://blogs.dnalc.org/2010/04/29/dna-day-2010-what-me-worry-about-my-dna/#comment-8491"><span class="avatar"><img alt='' src='http://1.gravatar.com/avatar/d378d3a40a3590dd63b538282ae6b78a?s=32&d=http%3A%2F%2F1.gravatar.com%2Favatar%2Fad516503a11cd5ca435acc9bb6523536%3Fs%3D32&r=G' class='avatar avatar-32 photo' height='32' width='32' /></span><span class="entry">Mohammed Khalfan: <span class="details"> Hi Traci, you should check this website out http://www.23andme.com/ - just might be what you're...</span></span></a></li> <li class="clear-block"><a title="Posted in: IQ Tests as a Measure of Intelligence" class="fadeThis" href="http://blogs.dnalc.org/2011/09/28/iq-tests-as-a-measure-of-intelligence/#comment-5440"><span class="avatar"><img alt='' src='http://0.gravatar.com/avatar/6b23915f2fdd2da3dc5c657112de54a5?s=32&d=http%3A%2F%2F0.gravatar.com%2Favatar%2Fad516503a11cd5ca435acc9bb6523536%3Fs%3D32&r=G' class='avatar avatar-32 photo' height='32' width='32' /></span><span class="entry">Sue: <span class="details"> I agree. IQ tests are overated. They are based on assumptions about the nature of intelligence,...</span></span></a></li> <li class="clear-block"><a title="Posted in: Cancer Overtreatment. When the solution is worse than the problem." class="fadeThis" href="http://blogs.dnalc.org/2011/12/13/cancer-overtreatment-when-the-solution-is-worse-than-the-problem/#comment-5439"><span class="avatar"><img alt='' src='http://0.gravatar.com/avatar/ad516503a11cd5ca435acc9bb6523536?s=32' class='avatar avatar-32 photo avatar-default' height='32' width='32' /></span><span class="entry">points of view: <span class="details"> On My Twitter Feed... Then I checked my personal feed and saw somebody posting the link to the...</span></span></a></li> <li class="clear-block"><a title="Posted in: Tag…You’re It!" class="fadeThis" href="http://blogs.dnalc.org/2012/01/19/tag-youre-it/#comment-5359"><span class="avatar"><img alt='' src='http://1.gravatar.com/avatar/52935aba909ed59a5789008268b14fdb?s=32&d=http%3A%2F%2F1.gravatar.com%2Favatar%2Fad516503a11cd5ca435acc9bb6523536%3Fs%3D32&r=G' class='avatar avatar-32 photo' height='32' width='32' /></span><span class="entry">talha: <span class="details"> the wonders of science i wanna be performing this epigenetic tag therapy.</span></span></a></li> <li class="clear-block"><a title="Posted in: Merry Christmas to Hemophilia Patients" class="fadeThis" href="http://blogs.dnalc.org/2011/12/15/merry-christmas-to-hemophilia-patients/#comment-5358"><span class="avatar"><img alt='' src='http://1.gravatar.com/avatar/52935aba909ed59a5789008268b14fdb?s=32&d=http%3A%2F%2F1.gravatar.com%2Favatar%2Fad516503a11cd5ca435acc9bb6523536%3Fs%3D32&r=G' class='avatar avatar-32 photo' height='32' width='32' /></span><span class="entry">talha: <span class="details"> this is just a tip of an iceberg whats gonna happen more and more can only be expected from gene...</span></span></a></li> <li class="clear-block"><a title="Posted in: DNA DAY 2010: What, me worry about my DNA?" class="fadeThis" href="http://blogs.dnalc.org/2010/04/29/dna-day-2010-what-me-worry-about-my-dna/#comment-4616"><span class="avatar"><img alt='' src='http://1.gravatar.com/avatar/fe0f32261332c54b99b24c06881c2573?s=32&d=http%3A%2F%2F1.gravatar.com%2Favatar%2Fad516503a11cd5ca435acc9bb6523536%3Fs%3D32&r=G' class='avatar avatar-32 photo' height='32' width='32' /></span><span class="entry">Traci: <span class="details"> How would I go about getting my DNA tested? Being an adopted child, we have exhausted legal alleys...</span></span></a></li> <li class="clear-block"><a title="Posted in: AIDS Cure UPDATE" class="fadeThis" href="http://blogs.dnalc.org/2011/10/15/aids-cure-update/#comment-1607"><span class="avatar"><img alt='' src='http://1.gravatar.com/avatar/997a441b2802e625590c2adc4ea2545f?s=32&d=http%3A%2F%2F1.gravatar.com%2Favatar%2Fad516503a11cd5ca435acc9bb6523536%3Fs%3D32&r=G' class='avatar avatar-32 photo' height='32' width='32' /></span><span class="entry">Heaven: <span class="details"> This is really amazing. This is just another step to curing some of the most devastating diseases...</span></span></a></li> <li class="clear-block"><a title="Posted in: Compulsive Hoarding" class="fadeThis" href="http://blogs.dnalc.org/2011/11/10/compulsive-hoarding/#comment-1245"><span class="avatar"><img alt='' src='http://0.gravatar.com/avatar/cf95176c58575d503b402764e9710135?s=32&d=http%3A%2F%2F0.gravatar.com%2Favatar%2Fad516503a11cd5ca435acc9bb6523536%3Fs%3D32&r=G' class='avatar avatar-32 photo' height='32' width='32' /></span><span class="entry">Eileen @ Space Matters: <span class="details"> You've got some very interesting info here! Here's some places to go to get do some more...</span></span></a></li> </ul> </div> </div> </div> </div> </div> <!-- tabbed content --> </div></li><li class="block"><div class="block-twitter clear-block" id="instance-twitterwidget-3"><h3 class="title"><span>DNALC Twitter Feed</span></h3><div class="block-div"></div><div class="block-div-arrow"></div> <div class="twitter-content clear-block" id="twitterwidget-3"> <script type="text/javascript"> /* <![CDATA[ */ // init jQuery(document).ready(function(){ jQuery.ajax({ // load tweets trough ajax to avoid waiting for twitter's response type: "GET",url: "http://blogs.dnalc.org",data: { widget_id: '3', twituser: 'dnalc', twitcount: '4', get_twitter_data: 1 }, beforeSend: function() {jQuery("#twitterwidget-3 .loading").show("slow");}, complete: function() { jQuery("#twitterwidget-3 .loading").hide("fast");}, success: function(html){ jQuery("#twitterwidget-3").html(html); jQuery("#twitterwidget-3").show("slow"); } }); }); /* ]]> */ </script> <div class="loading">Loading tweets...</div> </div> <a class="followMe" href="http://www.twitter.com/dnalc"><span>Follow me on Twitter!</span></a> </div></li><li class="block"><div class="block-jetpack_subscription_widget clear-block" id="instance-blog_subscription-3"><h3 class="title"><span><label for="subscribe-field">Subscribe to Blog via Email</label></span></h3><div class="block-div"></div><div class="block-div-arrow"></div> <a name="subscribe-blog"></a> <form action="" method="post" accept-charset="utf-8" id="subscribe-blog"> <p>Enter your email address to subscribe to this blog and receive notifications of new posts by email.</p> <p><input type="text" name="email" style="width: 95%; padding: 1px 2px" value="Email Address" id="subscribe-field" onclick="if ( this.value == 'Email Address' ) { this.value = ''; }" onblur="if ( this.value == '' ) { this.value = 'Email Address'; }" /></p> <p> <input type="hidden" name="action" value="subscribe" /> <input type="hidden" name="source" value="http://blogs.dnalc.org/tag/biology/" /> <input type="hidden" name="sub-type" value="widget" /> <input type="hidden" name="redirect_fragment" value="blog_subscription-3" /> <input type="hidden" id="_wpnonce" name="_wpnonce" value="56d7425289" /> <input type="submit" value="Subscribe" name="jetpack_subscriptions_widget" /> </p> </form> </div></li><li class="block"><div class="block-widget_meta clear-block" id="instance-meta-3"><h3 class="title"><span>Meta</span></h3><div class="block-div"></div><div class="block-div-arrow"></div> <ul> <li><a href="http://blogs.dnalc.org/wp-login.php">Log in</a></li> <li><a href="http://blogs.dnalc.org/feed/" title="Syndicate this site using RSS 2.0">Entries <abbr title="Really Simple Syndication">RSS</abbr></a></li> <li><a href="http://blogs.dnalc.org/comments/feed/" title="The latest comments to all posts in RSS">Comments <abbr title="Really Simple Syndication">RSS</abbr></a></li> <li><a href="http://wordpress.org/" title="Powered by WordPress, state-of-the-art semantic personal publishing platform.">WordPress.org</a></li> </ul> </div></li> </ul> </div> </div> </div> <!-- /main content --> <!-- footer --> <div id="footer"> <div class="page-content"> <div id="copyright"> 漏 2011, <a href="http://www.dnalc.org">DNA Learning Center</a>, <a href="http://www.cshl.edu">Cold Spring Harbor Laboratory</a>. 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