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openSNP | rs4481887
<!DOCTYPE html> <html lang="en"> <head> <meta charset="utf-8" http-equiv="X-UA-Compatible" content="IE=edge"> <title>openSNP | rs4481887</title> <link rel="shortcut icon" href="/favicon.ico" /> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1, maximum-scale=1" /> <link rel="stylesheet" media="screen" href="/assets/application-103f393d66a70948281b7e5ee5659703b79fd7135f25a81ff020a9d69d493174.css" /> <script src="/assets/application-51914e357728cb5c966cbb431070efbf663f9e10e48f2eacf29fde995217a149.js"></script> <meta name="csrf-param" content="authenticity_token" /> <meta name="csrf-token" content="XTJTWGbLR7inAkxx3pqgNOyFhuPmrH/YqEELNfZ5OLw6MMyKpg2qXpkBUY4yrbpszb8RRTn6NPWaRKjVCNsuXQ==" /> </head> <body> <nav class="navbar-default navbar-menu"> <div class="container"> <div class="navbar-header"> <a class="navbar-brand navbar-menu__brand" href="/">openSNP</a> <button type="button" class="navbar-toggle navbar-menu__hamburger-menu" data-toggle="collapse" data-target=".navbar-collapse"> <span class="sr-only">Toggle</span> <span class="navbar-menu__hamburger-menu-icon icon-bar"></span> <span class="navbar-menu__hamburger-menu-icon icon-bar"></span> <span class="navbar-menu__hamburger-menu-icon icon-bar"></span> </button> </div> <ul class="nav navbar-nav navbar-right collapse navbar-collapse"> <li><a class="navbar-menu__options" href="/news">News</a></li> <li class="dropdown"> <a href="#" class="navbar-menu__options dropdown-toggle" data-toggle="dropdown" role="button" aria-haspopup="true" aria-expanded="false">Data<span class="caret"></span></a> <ul class="dropdown-menu navbar-menu__info-menu"> <li><a class="navbar-menu__options" href="/snps">SNPs</a></li> <li><a class="navbar-menu__options" href="/genotypes">Genotypes</a></li> <li><a class="navbar-menu__options" href="/phenotypes">Phenotypes</a></li> <li><a class="navbar-menu__options" href="/picture_phenotypes">Phenotypes Pictures</a></li> <li role="separator" class="divider"></li> <li><a class="navbar-menu__options" href="/openhumans">Open Humans Connections</a></li> </ul> </li> <li><a class="navbar-menu__options" href="/updates">Latest Data</a></li> <li class="dropdown"> <a href="#" class="navbar-menu__options dropdown-toggle" data-toggle="dropdown" role="button" aria-haspopup="true" aria-expanded="false">About<span class="caret"></span></a> <ul class="dropdown-menu navbar-menu__info-menu"> <li><a class="navbar-menu__options" href="/about-us">About Us</a></li> <li><a class="navbar-menu__options" href="/statistics">Statistics</a></li> <li role="separator" class="divider"></li> <li><a class="navbar-menu__options" href="/faq">FAQ</a></li> </ul> </li> <li><a class="navbar-menu__options" href="/signin">Sign In</a></li> <li> <a class="navbar-menu__options hidden-xs" href="#" data-js='search-button'> <span class="glyphicon glyphicon-search" aria-hidden="true"></span> </a> </li> </ul> </div> </nav> <form class="navbar-form navbar-left navbar-menu__search-input" data-js="search-form" action="/search" accept-charset="UTF-8" method="get"><input name="utf8" type="hidden" value="✓" /> <div class="input-group input-group-sm navbar-menu__search-input-content"> <span class="input-group-addon" id="basic-addon1"><span class="glyphicon glyphicon-search" aria-hidden="true"></span></span> <input type="text" name="search" id="search" placeholder="Search" class="form-control" /> </div> </form> <div class="container-fluid warnings_container" id="alert-messages"> <div class="warning__alert alert alert-danger text-center center-block" data-dismiss="alert"> <button type="button" class="close" data-dismiss="alert">x</button> <strong> openSNP is sunsetting, we will remove this website and delete all data on April 30, 2025. You can <a href="https://tzovar.as/sunsetting-opensnp/">read more about the reasons here</a>. </strong> </div> </div> <noscript> <div class="container-fluid warnings_container" id="alert-messages"> <div class="warning__alert alert alert-danger text-center center-block" data-dismiss="alert"> <button type="button" class="close" data-dismiss="alert">x</button> <strong>It seems like you have JavaScript disabled. This will make some features of openSNP.org, like the drop-down menus, break.</strong> </div> </noscript> <div class="container-fluid warnings_container" id="alert-messages"> <div id="flash_notice" class="alert alert-success" style="display:none"></div> </div> <div class="general__container container"> <h3 class="general__title">SNP rs4481887</h3> <h5 class="text-center">Basic Information</h5> <div class="table-responsive"> <table class="table"> <tr> <td class="table-cell vertical-centered"><b>Name</b></td> <td class="table-cell vertical-centered">rs4481887</td> </tr> <tr> <td class="table-cell vertical-centered"><b>Chromosome</b></td> <td class="table-cell vertical-centered">1</td> </tr> <tr> <td class="table-cell vertical-centered"><b>Position</b></td> <td class="table-cell vertical-centered">248333561</td> </tr> <tr> <td class="table-cell vertical-centered"><b><a href="#" data-toggle="tooltip" data-placement="left" data-html="true" title="The <em>Weight of Evidence</em> reflects how much information <em>openSNP</em> has mined for this SNP. An entry in <em>SNPedia</em> is worth 5 points. A paper in the <em>PLoS</em> or on <em>Genome.gov</em> or an annotation by the <em>Personal Genome Project</em> are worth 2 points. A paper on <em>Mendeley</em> is worth 1 point.">Weight of evidence</a></b></td> <td class="table-cell vertical-centered">21</td> </tr> </table> </div> <div class="row"> <div class="col-md-3"> </div> <div class="col-md-3 snps__graphs"> <h4 class="text-center"> <a href="#" data-toggle="tooltip" data-placement="left" data-html="true" title="How the different genetic variation at this position is distributed over all <em>openSNP</em> users."> Genotype Frequency </a> </h4> <div id="freq_chart" class="center-block" style="height:200px; width:200px;"></div> </div> <div class="col-md-3 snps__graphs"> <h4 class="text-center"> <a href="#" data-toggle="tooltip" data-placement="left" data-html="true" title="How the single nucleotides on this position are distributed over all <em>openSNP</em> users."> Allele Frequency </a> </h4> <div id="allele_chart" class="center-block" style="height:200px; width:200px;"></div> </div> </div> <h5 class="text-center">Additional Information</h5> <ul class="nav nav-tabs"> <li class="active"><a href="#snpedia" aria-controls="snpedia" role="tab" data-toggle="tab">SNPedia (3)</a></li> <li><a href="#plos" aria-controls="plos" role="tab" data-toggle="tab">PLoS (1)</a></li> <li><a href="#mendeley" aria-controls="mendeley" role="tab" data-toggle="tab">Mendeley (2)</a></li> <li><a href="#pgp" aria-controls="pgp" role="tab" data-toggle="tab">Personal Genome Project (0)</a></li> <li><a href="#genomegov" aria-controls="genomegov" role="tab" data-toggle="tab">Genome.gov (1)</a></li> <li><a href="#users" aria-controls="users" role="tab" data-toggle="tab">Other users (1721)</a></li> <li><a href="#comments" aria-controls="comments" role="tab" data-toggle="tab">Comments (0)</a></li> </ul> <div class="tab-content"> <div id="snpedia" class="tab-pane clearfix active well tabs__one-tab"> <h3>Links to SNPedia</h3> <div class="table-responsive"> <table class="table"> <tr> <th>Title</th> <th>Summary</th> </tr> <tr> <td class="table-cell"> <a href="http://www.snpedia.com/index.php/Rs4481887(A;A)">rs4481887 A/A</a> </td> <td class="table-cell"><b>Most likely to smell asparagus metabolites in urine</b></td> </tr> <tr> <td class="table-cell"> <a href="http://www.snpedia.com/index.php/Rs4481887(G;G)">rs4481887 G/G</a> </td> <td class="table-cell"><b>Least likely to be able to smell asparagus metabolites in urine</b></td> </tr> <tr> <td class="table-cell"> <a href="http://www.snpedia.com/index.php/Rs4481887(A;G)">rs4481887 A/G</a> </td> <td class="table-cell"><b>More likely to be able to smell asparagus metabolites in urine</b></td> </tr> </table> </div> <div class="small"> Note: For some SNPs, testing providers detect the genotype from the opposite strand of DNA, so that the genotypes listed on openSNP don't appear here. In those cases, please replace "A" by "T" or "G" by "C" (and vice-versa). </div> </div> <div id="plos" class="tab-pane clearfix well tabs__one-tab"> <h3>Publications on this SNP on the Public Library of Science:</h3> <div class="table-responsive"> <table class="table table-hover" id="PaperPlos"> <thead> <tr> <th>First Author</th> <th>Title</th> <th>Year of Publication</th> <th># of readers</th> </tr> </thead> <tbody> <tr> <td class="table-cell vertical-centered">Nicholas Eriksson</td> <td class="table-cell vertical-centered"><a href="https://doi.org/10.1371/journal.pgen.1000993">Web-Based, Participant-Driven Studies Yield Novel Genetic Associations for Common Traits</a></td> <td class="table-cell vertical-centered">2010</td> <td class="table-cell vertical-centered">71111</td> </tr> </tbody> </table> </div> </div> <div id="mendeley" class="tab-pane clearfix well tabs__one-tab"> <h3>Publications on this SNP on Mendeley</h3> <div class="table-responsive"> <table class="table table-hover" id="PaperMendeley"> <thead> <tr> <th>First Author</th> <th>Title</th> <th>Pub. Year</th> <th># of Readers</th> <th>DOI</th> </tr> </thead> <tbody> <tr> <td class="table-cell vertical-centered">Marcia Levin Pelchat</td> <td class="table-cell vertical-centered"><a href="http://www.mendeley.com/catalog/excretion-perception-characteristic-odor-urine-after-asparagus-ingestion-psychophysical-genetic-stud/">Excretion and perception of a characteristic odor in urine after asparagus ingestion: a psychophysical and genetic study.</a></td> <td class="table-cell vertical-centered">2011</td> <td class="table-cell vertical-centered">16</td> <td class="table-cell vertical-centered"><a href="https://doi.org/10.1093/chemse/bjq081">10.1093/chemse/bjq081</a><img src="/assets/oa_logo-3fe7f006c5ef1789206c801af1f0d0538300f10d15d3a6c1285e1dfe3e8d62b5.png" alt="Oa logo" /></td> </tr> <tr> <td class="table-cell vertical-centered">Marcia Levin Pelchat</td> <td class="table-cell vertical-centered"><a href="http://www.mendeley.com/research/excretion-perception-characteristic-odor-urine-after-asparagus-ingestion-psychophysical-genetic-study/">Excretion and Perception of a Characteristic Odor in Urine after Asparagus Ingestion: a Psychophysical and Genetic Study</a></td> <td class="table-cell vertical-centered">2011</td> <td class="table-cell vertical-centered">12</td> <td class="table-cell vertical-centered"><a href="https://doi.org/10.1093/chemse/bjq081">10.1093/chemse/bjq081</a></td> </tr> </tbody> </table> </div> </div> <div id="pgp" class="tab-pane clearfix well tabs__one-tab"> <h3>Evidence compiled by the <em>Personal Genome Project</em></h3> There are no results from the <em>Personal Genome Project</em> yet. Please come back later. </div> <div id="genomegov" class="tab-pane clearfix well tabs__one-tab"> <h3>Publications listed by <em>Genome.gov</em></h3> <div class="table-responsive"> <table class="table table-hover" id="PaperGenomeGov"> <thead> <tr> <th>First Author</th> <th>Title</th> <th>Journal</th> <th>Publication Date</th> <th>Trait</th> <th>p-value</th> <th>Confidence Interval</th> </tr> </thead> <tbody> <tr> <td class="table-cell vertical-centered">Eriksson N</td> <td class="table-cell vertical-centered"><a href="http://www.ncbi.nlm.nih.gov/pubmed/20585627">Web-based, participant-driven studies yield novel genetic associations for common traits.</a></td> <td class="table-cell vertical-centered">PLoS Genet</td> <td class="table-cell vertical-centered">06/24/2010</td> <td class="table-cell vertical-centered">Common traits (Other)</td> <td class="table-cell vertical-centered">7.0e-24 (asparagus anosmia)</td> <td class="table-cell vertical-centered">[NR] </td> </tr> </tbody> </table> </div> </div> <div id="users" class="tab-pane clearfix well tabs__one-tab"> <h3>Users who share this SNP:</h3> <div id="user-list"></div> <script type="text/javascript"> $.ajax({ url: "/user_snps", data: { snp_name: 'rs4481887', local_genotype: '' }, success: function (html) { $("#user-list").append(html); } }); </script> </div> <div id="comments" class="tab-pane clearfix well tabs__one-tab"> </div> </div> <div class="well snps__genome-browser"> <h5 class="text-center">Genome Browser</h5> <script type="text/javascript"> new Browser({ chr: '1', viewStart: 248323561, viewEnd: 248343561, cookieKey: 'rs4481887', pageName: 'rs4481887', coordSystem: { speciesName: 'Human', taxon: 9606, auth: 'GrCh', version: '38', ucscName: 'hg38' }, sources: [{name: 'Genome', twoBitURI: 'https://www.biodalliance.org/datasets/hg38.2bit', tier_type: 'sequence'}, {name: 'Genes', desc: 'Gene structures from GENCODE 21', bwgURI: 'https://www.biodalliance.org/datasets/GRCh38/gencode.v21.annotation.bb', stylesheet_uri: 'https://www.biodalliance.org/stylesheets/gencode2.xml', collapseSuperGroups: true, trixURI: 'https://www.biodalliance.org/datasets/GRCh38/gencode.v21.annotation.ix'} ], searchEndpoint: new DASSource('https://www.biodalliance.org/das/hsa_59_37d'), browserLinks: { Ensembl: 'http://www.ensembl.org/Homo_sapiens/Location/View?r=${chr}:${start}-${end}', UCSC: 'http://genome.ucsc.edu/cgi-bin/hgTracks?db=hg19&position=chr${chr}:${start}-${end}', }, forceWidth: 900, noPersist: true, disablePoweredBy: true }); </script> <div id="rs4481887"></div> <script type="text/javascript"> $(document).ready(function () { var freq_data=[ ['GG',0.59], ['AG',0.35], ['AA',0.05], ['--',0.00], ['00',0.00] ]; var plot1 = jQuery.jqplot ('freq_chart', [freq_data], { /*seriesColors: ["#B0EDFF","#8EB5E8","#6E7CDB","#5F4DD6","#4823AD"],*/ seriesDefaults: { renderer: jQuery.jqplot.PieRenderer, rendererOptions: { showDataLabels: true, fill: false } }, legend: { show:true, location: 'e',drawBorder: false }, grid: { shadow:false, borderWidth: 0, background: '#ffffff'} } ); var allele_data=[ ['A', 0.22], ['T', 0.0], ['G', 0.76], ['C', 0.0], ['-', 0.00], ['0', 0.00] ]; var plot2 = jQuery.jqplot ('allele_chart', [allele_data], { /*seriesColors: ["#B0EDFF","#8EB5E8","#6E7CDB","#5F4DD6","#4823AD"],*/ seriesDefaults: { dataLabelPositionFactor: 3, renderer: jQuery.jqplot.PieRenderer, rendererOptions: { showDataLabels: true, fill: false } }, legend: { show:true, location: 'e' }, grid: { shadow:false, borderWidth: 0, background: '#ffffff'} } ); }); </script> </div> </div> <div class="footer"> <div class="container"> <div class="row"> <div class="col-md-2 col-xs-2"> <h4>Contacts</h4> <ul class="list-unstyled"> <li><a href="http://opensnp.wordpress.com">Blog</a></li> <li><a href="http://www.twitter.com/openSNPorg">Twitter</a></li> <li><a href="mailto:info@opensnp.org">Mail</a></li> <li><a href="https://github.com/openSNP/snpr">GitHub</a></li> </ul> </div> <div class="col-md-4 col-md-offset-2 col-xs-6 col-xs-offset-3" style="margin-bottom: 10px;"> <p class="footer__texts"> Our hosting is made possible thanks to the kind support of <b><a href="https://patreon.com/openSNP">our patrons on Patreon</a></b>. 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