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KEGG COMPOUND: C06868
<!doctype html> <html><head> <title>KEGG COMPOUND: C06868</title> <link type="text/css" rel="stylesheet" href="/css/gn2.css?1744226200"> <link type="text/css" rel="stylesheet" href="/css/bget.css?1744226200"> <meta name="viewport" content="width=device-width, initial-scale=1.0"> <link type="text/css" rel="stylesheet" href="/css/bgetm.css?1744226200" media="only screen and (max-width: 768px)"> <style>.kcfd{display:none;}</style> <script> <!-- var getElementsByClassName = document.getElementsByClassName ? function (cl){ return document.getElementsByClassName(cl); } : function (cl){ var elms = []; var objs = document.getElementsByTagName('*'); for(var i=0;i<objs.length;i++){ var obj = objs[i]; if(obj.className == cl){ elms.push(obj); } } return elms; }; function toggleField(clk,cl,show,hide){ var objs = getElementsByClassName(cl); for(var i=0;i<objs.length;i++){ var obj = objs[i]; if(!obj.style.display||obj.style.display == 'none'){ obj.style.display = 'block'; clk.innerHTML = ' « '+hide; 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id="form1" name="form1"></form><table class="w1" width="650"> <tr> <td class="fr2 w1"> <table width="650" class="w2"> <tr><th class="th20 deft tal vmid"><span class="nowrap">Entry</span></th> <td class="td20 defd"><table class="w1" width="100%"><tr><td class="tal pd0"><code><span class="nowrap">C06868 Compound <br> </span></code></td></tr></table></td></tr> <tr><th class="th21 deft tal vtop"><span class="nowrap">Name</span></th> <td class="td21 defd"><div class="cel"><div class="cel">Carbamazepine<br> </div></div></td></tr> <tr><th class="th20 deft tal vtop"><span class="nowrap">Formula</span></th> <td class="td20 defd"><div class="cel">C15H12N2O<br> </div></td></tr> <tr><th class="th21 deft tal vtop"><span class="nowrap">Exact mass</span></th> <td class="td21 defd"><div class="cel">236.0950<br> </div></td></tr> <tr><th class="th20 deft tal vtop"><span class="nowrap">Mol weight</span></th> <td class="td20 defd"><div class="cel">236.27<br> </div></td></tr> <tr><th class="th21 deft tal vtop"><span class="nowrap">Structure</span></th> <td class="td21 defd"><a href="/Fig/compound/C06868.gif"><img name="img0" src="/Fig/compound/C06868.gif" style="max-width:600px" border=0></a><br> <button class="btn" onclick="location.href='/entry/-f+m+C06868';return false;">Mol file</button><button class="btn" onclick="location.href='/entry/-f+k+C06868';return false;">KCF file</button><button class="btn" onclick="location.href='/tools-bin/strsearch_view?ENTRY=C06868&PROGRAM=simcomp&DATABASE=compound';return false;">DB search</button></td></tr> <tr><th class="th20 deft tal vtop"><span class="nowrap">Remark</span></th> <td class="td20 defd"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap">Same as: </span></td><td><a href="/entry/D00252">D00252</a></td></tr></table></td></tr> <tr><th class="th21 deft tal vtop"><span class="nowrap">Reaction</span></th> <td class="td21 defd"><div class="cel"><a href="/entry/R08312">R08312</a> <a href="/entry/R08313">R08313</a> <a href="/entry/R08317">R08317</a><br> </div></td></tr> <tr><th class="th20 deft tal vtop"><span class="nowrap">Pathway</span></th> <td class="td20 defd"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap"><a href="/pathway/map00982+C06868">map00982</a> </span></td><td>Drug metabolism - cytochrome P450</td></tr></table></td></tr> <tr><th class="th21 deft tal vtop"><span class="nowrap">Enzyme</span></th> <td class="td21 defd"><div class="cel"><a href="/entry/1.14.14.1">1.14.14.1</a> 1.14.14.-<br> </div></td></tr> <tr><th class="th20 deft tal vtop"><span class="nowrap">Brite</span></th> <td class="td20 defd"><div class="cel"><span class="nowrap">Anatomical Therapeutic Chemical (ATC) classification [BR:<a href="/brite/br08303+D00252">br08303</a>]<br> N NERVOUS SYSTEM<br> N03 ANTIEPILEPTICS<br> N03A ANTIEPILEPTICS<br> N03AF Carboxamide derivatives<br> N03AF01 Carbamazepine<br> D00252 Carbamazepine (JP18/USP/INN) <JP/US><br> USP drug classification [BR:<a href="/brite/br08302+D00252">br08302</a>]<br> Anticonvulsants<br> Sodium Channel Agents<br> Carbamazepine<br> D00252 Carbamazepine (JP18/USP/INN)<br> Bipolar Agents<br> Mood Stabilizers<br> Carbamazepine<br> D00252 Carbamazepine (JP18/USP/INN)<br> Central Nervous System Agents<br> Central Nervous System, Other<br> Carbamazepine<br> D00252 Carbamazepine (JP18/USP/INN)<br> Therapeutic category of drugs in Japan [BR:<a href="/brite/br08301+D00252">br08301</a>]<br> 1 Agents affecting nervous system and sensory organs<br> 11 Agents affecting central nervous system<br> 113 Antiepileptics<br> 1139 Others<br> D00252 Carbamazepine (JP18/USP/INN)<br> 117 Psychotropics<br> 1179 Others<br> D00252 Carbamazepine (JP18/USP/INN)<br> Drug groups [BR:<a href="/brite/br08330+D00252">br08330</a>]<br> Neuropsychiatric agent<br> DG03199 Antiepileptic agent<br> DG02034 Carboxamide antiepileptic<br> D00252 Carbamazepine<br> Metabolizing enzyme substrate<br> DG01633 CYP3A/CYP3A4 substrate<br> DG02913 CYP3A4 substrate<br> D00252 Carbamazepine<br> Metabolizing enzyme inducer<br> DG02853 CYP3A/CYP3A4 inducer<br> DG01635 CYP3A4 inducer<br> D00252 Carbamazepine<br> Transporter inducer<br> DG01893 ABCB1 inducer<br> D00252 Carbamazepine<br> Drug classes [BR:<a href="/brite/br08332+D00252">br08332</a>]<br> Neuropsychiatric agent<br> DG03199 Antiepileptic agent<br> D00252 Carbamazepine<br> Target-based classification of drugs [BR:<a href="/brite/br08310+D00252">br08310</a>]<br> Ion channels<br> Voltage-gated ion channels<br> Sodium channels<br> SCN1A<br> D00252 Carbamazepine (JP18/USP/INN) <JP/US><br> SCN2A<br> D00252 Carbamazepine (JP18/USP/INN) <JP/US><br> SCN3A<br> D00252 Carbamazepine (JP18/USP/INN) <JP/US><br> SCN4A<br> D00252 Carbamazepine (JP18/USP/INN) <JP/US><br> SCN5A<br> D00252 Carbamazepine (JP18/USP/INN) <JP/US><br> SCN8A<br> D00252 Carbamazepine (JP18/USP/INN) <JP/US><br> SCN9A<br> D00252 Carbamazepine (JP18/USP/INN) <JP/US><br> SCN10A<br> D00252 Carbamazepine (JP18/USP/INN) <JP/US><br> SCN11A<br> D00252 Carbamazepine (JP18/USP/INN) <JP/US><br> Drugs listed in the Japanese Pharmacopoeia [BR:<a href="/brite/br08311+D00252">br08311</a>]<br> Chemicals<br> D00252 Carbamazepine<br> Drug metabolizing enzymes and transporters [<a href="/kegg/drug/br08309.html?id=D00252">br08309.html</a>]<br> Drug metabolizing enzymes<br> D00252<br> Drug transporters<br> D00252<br> Pharmacogenomic biomarkers [<a href="/kegg/drug/br08341.html?id=D00252">br08341.html</a>]<br> Polymorphisms and mutations affecting drug response<br> D00252<br> </span></div><button class="btn" onclick="location.href='/kegg-bin/search_brite?option=-a&search_string=C06868';return false;">BRITE hierarchy</button></td></tr> <tr><th class="th21 deft tal vtop"><span class="nowrap">Other DBs</span></th> <td class="td21 defd"><table class="w1"><tr><td class="vtop pd0"><span class="nowrap">CAS: </span></td><td>298-46-4</td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap">PubChem: </span></td><td><a href="https://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=9085">9085</a></td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap">ChEBI: </span></td><td><a href="https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:3387">3387</a></td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap">PDB-CCD: </span></td><td><a href="https://www.ebi.ac.uk/pdbe-srv/pdbechem/chemicalCompound/show/N6W">N6W</a>[<a href="https://pdbj.org/mine/summary/N6W">PDBj</a>] </td></tr></table><table class="w1"><tr><td class="vtop pd0"><span class="nowrap">NIKKAJI: </span></td><td><a href="https://jglobal.jst.go.jp/en/redirect?Nikkaji_No=J8.590A">J8.590A</a></td></tr></table></td></tr> <tr><th class="th20 deft tal vtop"><span class="nowrap">KCF data</span></th> <td class="td20 defd"><button class="btn" id="kcfb1">Show</button><div class="kcfd" id="kcfd1"><br>ATOM 18<br> 1 C8y C 25.8139 -16.0918<br> 2 N1y N 27.0679 -15.4768<br> 3 C8y C 28.3385 -16.0677<br> 4 C8y C 28.6646 -17.4200<br> 5 C8y C 25.5184 -17.4703<br> 6 C2x C 27.8110 -18.5337<br> 7 C2x C 26.4090 -18.5521<br> 8 C8x C 24.7745 -15.1529<br> 9 C8x C 23.4416 -15.5834<br> 10 C8x C 23.1462 -16.9619<br> 11 C8x C 24.1856 -17.9009<br> 12 C8x C 30.0177 -17.7825<br> 13 C8x C 31.0081 -16.7920<br> 14 C8x C 30.6456 -15.4389<br> 15 C8x C 29.2926 -15.0764<br> 16 C5a C 27.1235 -14.0772<br> 17 O5a O 25.8857 -13.3793<br> 18 N1a N 28.3127 -13.3740<br> BOND 20<br> 1 3 4 1<br> 2 1 5 1<br> 3 4 6 1<br> 4 2 3 1<br> 5 5 7 1<br> 6 1 2 1<br> 7 6 7 2<br> 8 1 8 2<br> 9 8 9 1<br> 10 9 10 2<br> 11 10 11 1<br> 12 5 11 2<br> 13 4 12 2<br> 14 12 13 1<br> 15 13 14 2<br> 16 14 15 1<br> 17 15 3 2<br> 18 2 16 1<br> 19 16 17 2<br> 20 16 18 1<br> </div></td></tr> </table></td></tr></table> <br><span style="font-size:12px"><a href="/entry/cpd_ja:C06868">» Japanese version</a></span><br><br></td><td class="vtop"><div class="aw" style="margin-top:46px;"><div class="fm at th20"> All links </div> <div class="fm"><pre class="fm" style="margin-left:1em"> <span style="color:#006"><a href="/dbget-bin/get_linkdb?-t+6+cpd:C06868">Chemical substance (11)</a></span> <a href="/dbget-bin/get_linkdb?-t+pubchem+cpd:C06868">PubChem (1)</a> <a href="/dbget-bin/get_linkdb?-t+chebi+cpd:C06868">ChEBI (1)</a> <a href="/dbget-bin/get_linkdb?-t+hmdb+cpd:C06868">HMDB (1)</a> <a href="/dbget-bin/get_linkdb?-t+hsdb+cpd:C06868">HSDB (1)</a> <a href="/dbget-bin/get_linkdb?-t+massbank+cpd:C06868">MASSBANK (5)</a> <a href="/dbget-bin/get_linkdb?-t+nikkaji+cpd:C06868">NIKKAJI (1)</a> <a href="/dbget-bin/get_linkdb?-t+pdb-ccd+cpd:C06868">PDB-CCD (1)</a> <a href="/dbget-bin/get_linkdb?-t+alldb+cpd:C06868">All databases (11)</a> <br><a href="/dbget-bin/get_linkdb?-N+cpd:C06868">Download RDF</a> </pre> </div></div> </td></tr></table> <a href="/dbget/">DBGET</a> integrated database retrieval system</div> </body> </html>