CINXE.COM
Genome Research
<!DOCTYPE html PUBLIC "-//W3C//DTD XHTML 1.0 Strict//EN" "http://www.w3.org/TR/xhtml1/DTD/xhtml1-strict.dtd"> <html xmlns="http://www.w3.org/1999/xhtml" xml:lang="en" lang="en"> <head> <meta http-equiv="Content-Type" content="text/html; charset=UTF-8" /> <title>Genome Research </title> <meta name="googlebot" content="NOODP" /> <meta name="description" content="An international, peer-reviewed genome sciences journal featuring outstanding original research that offers novel insights into the biology of all organisms" /> <link rel="stylesheet" type="text/css" media="all" href="/shared/css/hw-global.css" /> <link rel="stylesheet" type="text/css" media="all" href="/shared/css/standard-designs/design2/main.css" /> <link rel="stylesheet" type="text/css" media="all" href="/publisher/css/hw-cshljnls-global.css" /> <link rel="stylesheet" type="text/css" media="all" href="/local/css/hw-journal-global.css" /> <link rel="stylesheet" type="text/css" media="all" href="/shared/css/hw-citation-2.0-hacks.css" /> <link rel="stylesheet" type="text/css" media="all" href="/publisher/css/hw-cshljnls-page-home.css" /> <link rel="stylesheet" type="text/css" media="all" href="/site/misc/custom-global.css" /> <link rel="alternate" type="application/rss+xml" title="Genome Research Current RSS" href="/rss/current.xml" /><script type="text/javascript" id="session-d7134676e1">var callbackToken='5157FE1EF6F9A86';</script><script type="text/javascript" src="/shared/js/jquery-min.js"></script><script type="text/javascript" src="/shared/js/fingerprint.js"></script><script type="text/javascript" src="/shared/js/hw-shared.js"></script><script type="text/javascript" src="/shared/js/design/hw-design1.js"></script><script type="text/javascript" src="/publisher/js/cshl-shared.js"></script><script type="text/javascript" src="/publisher/js/cshljnls-home.js"></script><script type="text/javascript" src="/site/misc/custom-global.js"></script></head> <body> <div class="hw-gen-page" id="pageid-home"> <div id="header"> <a href="http://www.cshlpress.com" rel="external-nw"><img src="/local/img/society_logo.gif" width="74" height="83" alt="Publisher Logo" id="main-logo" /></a><a href="/"></a><img title="Genome Research" alt="Genome Research" width="313" height="83" src="/local/img/journal_logo.gif" /> <p id="skip-link"> <a href="#content-block">Skip to main page content</a> </p> <ul class="button-list header-buttons"> <li class="no-link first"><span>HOME</span></li> <li><a href="/site/misc/about.xhtml" title="ABOUT"><span>ABOUT</span></a></li> <li><a href="/content/by/year" title="ARCHIVE"><span>ARCHIVE</span></a></li> <li><a href="http://submit.genome.org/" title="SUBMIT"><span>SUBMIT</span></a></li> <li><a href="/site/subscriptions/" title="SUBSCRIBE"><span>SUBSCRIBE</span></a></li> <li><a href="/site/misc/adinfo.xhtml" title="ADVERTISE"><span>ADVERTISE</span></a></li> <li><a href="/site/misc/ifora.xhtml" title="AUTHOR INFO"><span>AUTHOR INFO</span></a></li> <li><a href="/feedback" title="CONTACT"><span>CONTACT</span></a></li> <li class="last"><a href="/help/" title="HELP"><span>HELP</span></a></li> </ul> <div class="header-qs"> <form class="searchbox" action="/search" method="get"> <div> <label for="header-qs-input" id="header-qs-search-label">Search for Keyword:</label> <input value="" title="Search Genome Research" type="text" name="fulltext" id="header-qs-input" /><input type="hidden" name="submit" value="yes" /><label for="header-qs-search" id="header-qs-search-label">GO</label><input value="GO" alt="Link: Go" type="image" id="header-qs-search-go" src="/shared/img/standard-design/design2/go.gif" /> </div> <div class="adv-search-link"><a href="/search">Advanced Search</a></div> </form> </div> <div class="header-ac-elements"> <div class="inst-branding"> </div> <div id="authstring" class="suppress-header-login"> </div> <div id="hdr-login" class="suppress-header-login"></div> </div> <div class="banner-ads"> <ul> <li><a href="/cgi/adclick/?ad=57879&adclick=true&url=https%3A%2F%2Fbit.ly%2F3XReZAs" target="_blank"><img class="adborder0" title="Oxford Nanopore" src="//genome.cshlp.org/adsystem/graphics/19192250508037556/genome/ONT%20LB%20Bolder.jpg?ad=57879&adview=true" alt="Oxford Nanopore" /></a></li> </ul> </div> <div class="bar"> <div class="bar-inner"></div> </div> </div> <div id="content-block"> <div class="main-block"> <div class="cover-img-wrap"> <a id="cover-image" href="/content/current"> <img src="/content/vol34/issue11/home_cover.gif" title="Current Issue Cover" alt="Current Issue Cover" /> </a> </div> <h2 class="under-cover-info"><a title="Current Issue" href="/content/current" id="current-issue-label" class="current-link"><span class="current-date">November 2024</span></a></h2> <div class="cshl-announcements"> <p> <a href="/site/misc/top.xhtml">Top 10 Most Read Articles</a> </p> <p> <a href="/site/misc/terms.xhtml">Creative Commons Licensing</a> </p> <p> <a href="https://genome.cshlp.org/site/misc/open_access.xhtml">Open Access Publishing</a> </p> <div style="margin-left:0px;margin-top:27px;"> <h2 class="under-cover-info" style="margin-left:0px;margin-bottom:11px;"> <img alt="@genomeresearch" src="/site/misc/images1/icon_gr5.jpg" height="18px;" /> </h2> <table class="tpad0 tspace0" cellpadding="0" cellspacing="0"> <tr> <td class="cshlsm"> <a href="https://bsky.app/profile/genomeresearch.bsky.social" rel="external-nw" title="Bluesky"> <img alt="Bluesky" src="/site/misc/images1/icon_bs.png" /> </a> </td> <td class="cshlsm"> <a href="https://twitter.com/genomeresearch" rel="external-nw" title="X"> <img alt="X" src="/site/misc/images1/icon_tw.png" /> </a> </td> <td class="cshlsm"> <a href="https://genomic.social/@genomeresearch" rel="external-nw" title="Mastodon"> <img alt="Mastodon" src="/site/misc/images1/icon_ms.png" /> </a> </td> <td class="cshlsm"> <a href="https://www.linkedin.com/company/genome-research" rel="external-nw" title="LinkedIn"> <img alt="LinkedIn" src="/site/misc/images1/icon_ln.jpg" /> </a> </td> <td class="cshlsm"> <a href="https://www.instagram.com/genomeresearch/" rel="external-nw" title="Instagram"> <img alt="Instagram" src="/site/misc/images1/icon_ig.png" /> </a> </td> <td class="cshlsm"> <a href="https://www.threads.net/@genomeresearch" rel="external-nw" title="Threads"> <img alt="Threads" src="/site/misc/images1/icon_th.jpg" /> </a> </td> <td class="cshlsm"> <a href="https://www.facebook.com/genomeresearch/" rel="external-nw" title="Facebook"> <img alt="Facebook" src="/site/misc/images1/icon_fb.png" /> </a> </td> </tr> </table> </div> </div> <div class="other-pub"> <table style="padding:0;"> <tr> <td style="vertical-align:top;padding-right:10px;"> <img src="/site/misc/images/logo_sm.gif" alt="Other Cold Spring Harbor Publications" /> </td> <td> <table style="padding:0;"> <tr> <td> <img src="/site/misc/images/otherpub.gif" alt="Other Cold Spring Harbor Publications" /> </td> </tr> <tr> <td> <div id="mypubs"> <a href="http://molecularcasestudies.cshlp.org" rel="external-nw">Cold Spring Harbor Molecular Case Studies</a> <img src="site/misc/images/dot.gif" alt="" /> <a href="http://perspectivesinmedicine.cshlp.org" rel="external-nw">Cold Spring Harbor Perspectives in Medicine</a> <img src="site/misc/images/dot.gif" alt="" /> <a href="http://cshperspectives.cshlp.org" rel="external-nw">Cold Spring Harbor Perspectives in Biology</a> <img src="site/misc/images/dot.gif" alt="" /> <a href="http://cshprotocols.cshlp.org" rel="external-nw">Cold Spring Harbor Protocols</a> <img src="site/misc/images/dot.gif" alt="" /> <a href="http://symposium.cshlp.org" rel="external-nw">Cold Spring Harbor Symposia</a> <img src="site/misc/images/dot.gif" alt="" /> <a href="http://genesdev.cshlp.org" rel="external-nw">Genes & Development</a> <img src="site/misc/images/dot.gif" alt="" /> <a href="http://learnmem.cshlp.org" rel="external-nw">Learning & Memory</a> <img src="/site/misc/images/dot.gif" alt="" /> <a href="http://life-science-alliance.org" rel="external-nw">Life Science Alliance</a> <img src="/site/misc/images/dot.gif" alt="" /> <a href="http://rnajournal.cshlp.org" rel="external-nw">RNA</a> <img src="/site/misc/images/dot.gif" alt="" /> <a href="http://cshlpress.com" rel="external-nw">Books and Other Media</a> </div> </td> </tr> </table> </td> </tr> </table> </div> </div> <div class="main-block"> <h2 class="current-issue"><a title="Current Issue" href="/content/current" id="current-issue-label" class="current-link">Current Issue<span class="sep">:</span> <span class="current-date">November 2024</span></a></h2> <ul class="jnl-links"> <li> <h3><a title="Advance Online Articles" href="/content/early/recent" class="early-link">Advance Online Articles</a></h3> <p> <span>Last updated:</span> <span class="early-date">November 26, 2024</span> </p> </li> <li> <h3><a href="/content/by/year">Archive</a></h3> <p>August 1991<span class="sep"> - </span><span class="to-date"> November 2024 </span></p> </li> <li> <h3><a href="/site/press/Announcements.xhtml">GR in the News</a></h3> </li> <li> <h3><a href="/site/misc/ifora.xhtml">Author Information</a></h3> </li> <li> <h3><a href="/site/misc/alertland.xhtml">E-mail Alerts & RSS Feeds</a></h3> </li> <li> <h3><a href="/site/subscriptions/sample.dtl">Free Online Issue</a></h3> </li> <li> <h3><a href="/site/misc/classifieds.xhtml">Job Opportunities</a></h3> </li> </ul> <div class="in-this-issue"> <h2> In This Issue </h2> <table></table> <table> <tbody> <tr> <td style="vertical-align: middle; padding-right: 5px; font-size: 90%;" class="covlinesi"> <a href="/site/cl/CL_34_11_dis_canc.xhtml"> <img alt="" src="/site/misc/images/34_11_cl1.gif" /> </a> </td> <td class="covlines"> <a href="/site/cl/CL_34_11_dis_canc.xhtml">Rare disease and cancer genomics</a> </td> </tr> <tr> <td style="vertical-align: middle; padding-right: 5px; font-size: 90%;" class="covlinesi"> <a href="/site/cl/CL_34_11_long_read.xhtml"> <img alt="" src="/site/misc/images/34_11_cl2.gif" /> </a> </td> <td class="covlines"> <a href="/site/cl/CL_34_11_long_read.xhtml">Long-read RNA sequencing</a> </td> </tr> <tr> <td style="vertical-align: middle; padding-right: 5px; font-size: 90%;" class="covlinesi"> <a href="/site/cl/CL_34_11_chrom_lev.xhtml"> <img alt="" src="/site/misc/images/34_11_cl3.gif" /> </a> </td> <td class="covlines"> <a href="/site/cl/CL_34_11_chrom_lev.xhtml">T2T and chromosome-level assemblies</a> </td> </tr> <tr> <td style="vertical-align: middle; padding-right: 5px; font-size: 90%;" class="covlinesi"> <a href="/site/cl/CL_34_11_data_app.xhtml"> <img alt="" src="/site/misc/images/34_11_cl4.gif" /> </a> </td> <td class="covlines"> <a href="/site/cl/CL_34_11_data_app.xhtml">Novel long-read sequencing data approaches</a> </td> </tr> <tr> <td style="vertical-align: middle; padding-right: 5px; font-size: 90%;" class="covlinesi"> <a href="/site/cl/CL_34_11_det_char.xhtml"> <img alt="" src="/site/misc/images/34_11_cl5.gif" /> </a> </td> <td class="covlines"> <a href="/site/cl/CL_34_11_det_char.xhtml">Rapid pathogen detection and characterization</a> </td> </tr> </tbody> </table> <div class="in-this-issue" style="padding-top: 20px;"> <p style="margin-top: 8px; padding-top: 8px; font-size: 90%; line-height: 115%;"> <span style="color: rgb(51, 51, 102);"> <em>Genome Research</em> </span> is an international, continuously published, peer-reviewed journal that features outstanding original research providing novel insights into the genome biology of all organisms, including significant advances in genomic medicine. The journal also provides high-quality reviews and perspectives written by respected leaders in the field and reports cutting-edge computational biology and high-throughput methodologies. </p> </div> </div> </div> <div class="content-block-clear sb-div"></div> </div> <div id="col-3"> <ul class="tower-ads"> <li><a href="/cgi/adclick/?ad=57881&adclick=true&url=https%3A%2F%2Fbit.ly%2F3XReZAs" target="_blank"><img class="adborder0" title="Oxford Nanopore" src="//genome.cshlp.org/adsystem/graphics/09114706754487034/genome/ONT%20Tower%20Bolder.jpg?ad=57881&adview=true" alt="Oxford Nanopore" /></a></li> </ul> <div id="col-3-widget-placeholder" style="padding-top:12px;"></div> </div> <div id="footer"> <div class="bar"> <div class="footer-group footer-col-left"> <ul class="button-list footer-buttons"> <li class="no-link first"><span>Home</span></li> <li><a href="/site/misc/about.xhtml" title="About"><span>About</span></a></li> <li><a href="/content/by/year" title="Archive"><span>Archive</span></a></li> <li><a href="http://submit.genome.org/" title="Submit"><span>Submit</span></a></li> <li><a href="/site/subscriptions/" title="Subscribe"><span>Subscribe</span></a></li> <li><a href="/site/misc/adinfo.xhtml" title="Advertise"><span>Advertise</span></a></li> <li><a href="/site/misc/ifora.xhtml" title="Author Info"><span>Author Info</span></a></li> <li><a href="/feedback" title="Contact"><span>Contact</span></a></li> <li class="last"><a href="/help/" title="Help"><span>Help</span></a></li> </ul> <p class="copyright"><a href="http://www.cshlpress.com/" rel="external-nw">Copyright 漏 2024 by Cold Spring Harbor Laboratory Press</a></p> </div> <div class="footer-group footer-col-right"> <ul class="issns"> <li> <span>Print ISSN: </span> <span class="issn">1088-9051</span> </li> <li> <span>Online ISSN: </span> <span class="issn">1549-5469</span> </li> </ul> </div> </div> <div id="sub-footer"> <div id="intl-content" class="intl-content"> <p><span id="intl-header">For an alternate route to Genome Research use this URL:</span> <a href="http://intl-genome.cshlp.org" title="Alternate Route">http://intl-genome.cshlp.org</a> <span class="intl-help">[<a href="/help/using/alternate-route">More Information</a>]</span></p> </div> <ul class="footer-icon-group"> <li> <a target="_blank" href="http://www.projectcounter.org/"> <img border="0" alt="COUNTER Project" height="24" width="75" src="/publisher/icons/counter.gif" /> </a> </li> <li> <a target="_blank" href="http://www.dcprinciples.org/"> <img border="0" alt="DC Principles" height="57" width="75" src="/publisher/icons/dcprinciples.gif" /> </a> </li> <li> <a target="_blank" href="http://www.aginternetwork.org/en/"> <img border="0" alt="AGORA" height="20" width="89" src="/publisher/icons/logo_agora.gif" /> </a> </li> <li> <a target="_blank" href="http://www.who.int/hinari/en/"> <img border="0" alt="HINARI" height="20" width="94" src="/publisher/icons/logo_hinari.gif" /> </a> </li> <li> <a target="_blank" href="http://home.highwire.org/"> <img border="0" alt="HighWire Press" height="51" width="55" src="/shared/img/common/hplogo.gif" /> </a> </li> <li> <a target="_blank" href="http://www.crossref.org/fundref/index.html"> <img border="0" alt="CSHL" height="52px" width="115px" src="/publisher/icons/FundRef_logo.png" /> </a> </li> </ul> </div> <div class="block-2 sb-div"></div> <script type="text/javascript"> document.write(unescape("%3Cscript async src='https://www.googletagmanager.com/gtag/js?id=G-R8GM9H68DV'%3E%3C/script%3E")); </script><script> window.dataLayer = window.dataLayer || []; function gtag(){dataLayer.push(arguments);} gtag('js', new Date()); gtag('config', 'G-R8GM9H68DV'); </script> </div><script type="text/javascript"> document.write(unescape("%3Cscript async src='https://www.googletagmanager.com/gtag/js?id=G-1CWXPJ6EVC'%3E%3C/script%3E")); </script><script> window.dataLayer = window.dataLayer || []; function gtag(){dataLayer.push(arguments);} gtag('js', new Date()); gtag('config', 'G-1CWXPJ6EVC'); </script></div> </body> </html>