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Investigating the Impact of Treatment on New HIV Infections - PLOS Collections
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In November 2011 the HIV Modelling Consortium held a meeting in South Africa to focus on the cross-cutting issues of the impact of new scientific findings about HIV treatment preventing new infections. The group considered the feasibility of interventions, potential epidemiological impact, affordability, and new scientific observational studies and community trials. The nine reviews and one research article which comprise this collection arose from that meeting and provide insights into the factors which will support evidence-based decision-making in HIV prevention, with a focus on the use of antiretroviral treatment to prevent HIV transmission." /> <link rel="canonical" href="https://collections.plos.org/collection/tasp2012/" /> <meta property="og:locale" content="en_US" /> <meta property="og:type" content="article" /> <meta property="og:title" content="Investigating the Impact of Treatment on New HIV Infections - PLOS Collections" /> <meta property="og:description" content="The HIV Modelling Consortium aims to strengthen the support that mathematical modelling and related quantitative disciplines can provide to global decision-making in HIV. In November 2011 the HIV Modelling Consortium held a meeting in South Africa to focus on the cross-cutting issues of the impact of new scientific findings about HIV treatment preventing new infections. The group considered the feasibility of interventions, potential epidemiological impact, affordability, and new scientific observational studies and community trials. 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class="single-collection-header"> <div class="single-collection-header__text"> <span class="single-collection-header__label">Medicine & Health</span> <h1 class="single-collection-header__title">Investigating the Impact of Treatment on New HIV Infections</h1> <div class="single-collection-header__meta"> <time class="single-collection-header__post-date" datetime="2021-11-03T22:07:27+00:00">Published June 8, 2016</time> <span class="single-collection-header__terms">Partnered Collections, Special Issues</span> </div> <div class="single-collection-header__description"> <p>The <a href="http://www.hivmodelling.org/" target="_blank">HIV Modelling Consortium</a> aims to strengthen the support that mathematical modelling and related quantitative disciplines can provide to global decision-making in HIV. In November 2011 the HIV Modelling Consortium held a meeting in South Africa to focus on the cross-cutting issues of the impact of new scientific findings about HIV treatment preventing new infections. The group considered the feasibility of interventions, potential epidemiological impact, affordability, and new scientific observational studies and community trials. The nine reviews and one research article which comprise this collection arose from that meeting and provide insights into the factors which will support evidence-based decision-making in HIV prevention, with a focus on the use of antiretroviral treatment to prevent HIV transmission.</p> <p class="single-collection-header__image-credit">Image Credit: Psyberartist at flickr.com, Manta Ray Media/HIV Modelling Consortium</p> </div> </div> <div class="single-collection-header__featured-image" style="background-image: url('https://collections.plos.org/wp-content/uploads/sites/16/2020/10/9c471804e920b2f85d8f76fbb4138ef7bb8f697a3d09278a341c78237322ff06211.jpeg');"></div> </header> <div class="single-collection-content"> </div> <div class="single-collection-content__navigation"> <div class="single-collection-content__navigation-container"> <a class="single-collection-content__navigation-title" href="#"><span class="single-collection-content__navigation-hamburger"></span><span class="single-collection-content__navigation-title-text">Jump to section</span></a> <ul class="single-collection-content__navigation-list"> <li class="single-collection-content__navigation-item"> <a href="#reviews">Reviews</a> </li> <li class="single-collection-content__navigation-item"> <a href="#research-article">Research Article</a> </li> </ul> </div> </div> <div class="single-collection-container"> <div class="single-collection-sections"> <div class="single-collection-sections__section" id="reviews"> <span class="single-collection-sections__section-title">Reviews</span> <ul class="single-collection-sections__items"> <li class="single-collection-sections__article single-collection-sections__article--plos_article single-collection-sections__article--has-image-yes single-collection-sections__article--image-right single-collection-sections__article--image-size-large"> <a class="single-collection-sections__article-anchor" id="hiv-treatment-as-prevention-principles-of-good-hiv-epidemiology-modelling-for-public-health-decisionmaking-in-all-modes-of-prevention-and-evaluation"></a> <div class="single-collection-sections__article-image-container"> <a class="single-collection-sections__article-image" href="http://dx.plos.org/10.1371/journal.pmed.1001239" data-src="/wp-content/uploads/sites/16/indirect/c1d33623802e87345642e2fadbcc5977.jpg" title="10.1371/journal.pmed.1001239"></a> <div class="image-credit image-credit--tooltip"> <span class="image-credit__label">Image credit</span> <div class="image-credit__content">10.1371/journal.pmed.1001239</div> </div> </div> <div class="single-collection-sections__article-text"> <span class="single-collection-sections__article-label">PLOS Medicine</span> <span class="single-collection-sections__article-title"> <a href="http://dx.plos.org/10.1371/journal.pmed.1001239">HIV Treatment as Prevention: Principles of Good HIV Epidemiology Modelling for Public Health Decision-Making in All Modes of Prevention and Evaluation</a> </span> <div class="single-collection-sections__article-meta"> <span class="single-collection-sections__article-date">July 10, 2012</span> <span class="single-collection-sections__article-additional-meta-info">Wim Delva, David Wilson, Laith Abu-Raddad, Marelize Gorgens, David Wilson, Timothy Hallett, Alex Welte</span> </div> </div> </li> <li class="single-collection-sections__article single-collection-sections__article--plos_article single-collection-sections__article--has-image-yes single-collection-sections__article--image-right single-collection-sections__article--image-size-large"> <a class="single-collection-sections__article-anchor" id="hiv-treatment-as-prevention-considerations-in-the-design-conduct-and-analysis-of-cluster-randomized-controlled-trials-of-combination-hiv-prevention"></a> <div class="single-collection-sections__article-image-container"> <a class="single-collection-sections__article-image" href="http://dx.plos.org/10.1371/journal.pmed.1001250" data-src="/wp-content/uploads/sites/16/indirect/7ef7e1484f2a1b351207723a8639d017.jpg" title="10.1371/journal.pmed.1001250"></a> <div class="image-credit image-credit--tooltip"> <span class="image-credit__label">Image credit</span> <div class="image-credit__content">10.1371/journal.pmed.1001250</div> </div> </div> <div class="single-collection-sections__article-text"> <span class="single-collection-sections__article-label">PLOS Medicine</span> <span class="single-collection-sections__article-title"> <a href="http://dx.plos.org/10.1371/journal.pmed.1001250">HIV Treatment as Prevention: Considerations in the Design, Conduct, and Analysis of Cluster Randomized Controlled Trials of Combination HIV Prevention</a> </span> <div class="single-collection-sections__article-meta"> <span class="single-collection-sections__article-date">July 10, 2012</span> <span class="single-collection-sections__article-additional-meta-info">Marie-Claude Boily, Benoit M芒sse, Ramzi Alsallaq, Nancy Padian, Jeffrey Eaton, Juan Vesga, Timothy Hallett</span> </div> </div> </li> <li class="single-collection-sections__article single-collection-sections__article--plos_article single-collection-sections__article--has-image-yes single-collection-sections__article--image-right single-collection-sections__article--image-size-large"> <a class="single-collection-sections__article-anchor" id="hiv-treatment-as-prevention-natural-experiments-highlight-limits-of-antiretroviral-treatment-as-hiv-prevention"></a> <div class="single-collection-sections__article-image-container"> <a class="single-collection-sections__article-image" href="http://dx.plos.org/10.1371/journal.pmed.1001231" data-src="/wp-content/uploads/sites/16/indirect/eebb1b149c690ddff04ac64406dd141c.jpg" title="10.1371/journal.pmed.1001231"></a> <div class="image-credit image-credit--tooltip"> <span class="image-credit__label">Image credit</span> <div class="image-credit__content">10.1371/journal.pmed.1001231</div> </div> </div> <div class="single-collection-sections__article-text"> <span class="single-collection-sections__article-label">PLOS Medicine</span> <span class="single-collection-sections__article-title"> <a href="http://dx.plos.org/10.1371/journal.pmed.1001231">HIV Treatment as Prevention: Natural Experiments Highlight Limits of Antiretroviral Treatment as HIV Prevention</a> </span> <div class="single-collection-sections__article-meta"> <span class="single-collection-sections__article-date">July 10, 2012</span> <span class="single-collection-sections__article-additional-meta-info">David Wilson</span> </div> </div> </li> <li class="single-collection-sections__article single-collection-sections__article--plos_article single-collection-sections__article--has-image-yes single-collection-sections__article--image-right single-collection-sections__article--image-size-large"> <a class="single-collection-sections__article-anchor" id="hiv-treatment-as-prevention-the-utility-and-limitations-of-ecological-observation"></a> <div class="single-collection-sections__article-image-container"> <a class="single-collection-sections__article-image" href="http://dx.plos.org/10.1371/journal.pmed.1001260" data-src="/wp-content/uploads/sites/16/indirect/3e34ab0180f0e160fcda1bd88c7ff1c7.jpg" title="10.1371/journal.pmed.1001260"></a> <div class="image-credit image-credit--tooltip"> <span class="image-credit__label">Image credit</span> <div class="image-credit__content">10.1371/journal.pmed.1001260</div> </div> </div> <div class="single-collection-sections__article-text"> <span class="single-collection-sections__article-label">PLOS Medicine</span> <span class="single-collection-sections__article-title"> <a href="http://dx.plos.org/10.1371/journal.pmed.1001260">HIV Treatment as Prevention: The Utility and Limitations of Ecological Observation</a> </span> <div class="single-collection-sections__article-meta"> <span class="single-collection-sections__article-date">July 10, 2012</span> <span class="single-collection-sections__article-additional-meta-info">M Smith, Kimberly Powers, Kathryn Meussig, William Miller, Myron Cohen</span> </div> </div> </li> <li class="single-collection-sections__article single-collection-sections__article--plos_article single-collection-sections__article--has-image-yes single-collection-sections__article--image-right single-collection-sections__article--image-size-large"> <a class="single-collection-sections__article-anchor" id="hiv-treatment-as-prevention-debate-and-commentary鈥攚ill-early-infection-compromise-treatmentasprevention-strategies"></a> <div class="single-collection-sections__article-image-container"> <a class="single-collection-sections__article-image" href="http://dx.plos.org/10.1371/journal.pmed.1001232" data-src="/wp-content/uploads/sites/16/indirect/0283e11903606d6dde696920e185c0f3.jpg" title="10.1371/journal.pmed.1001232"></a> <div class="image-credit image-credit--tooltip"> <span class="image-credit__label">Image credit</span> <div class="image-credit__content">10.1371/journal.pmed.1001232</div> </div> </div> <div class="single-collection-sections__article-text"> <span class="single-collection-sections__article-label">PLOS Medicine</span> <span class="single-collection-sections__article-title"> <a href="http://dx.plos.org/10.1371/journal.pmed.1001232">HIV Treatment as Prevention: Debate and Commentary鈥擶ill Early Infection Compromise Treatment-as-Prevention Strategies?</a> </span> <div class="single-collection-sections__article-meta"> <span class="single-collection-sections__article-date">July 10, 2012</span> <span class="single-collection-sections__article-additional-meta-info">Myron Cohen, Christopher Dye, Christopher Fraser, William Miller, Kimberly Powers, Brian Williams</span> </div> </div> </li> <li class="single-collection-sections__article single-collection-sections__article--plos_article single-collection-sections__article--has-image-yes single-collection-sections__article--image-right single-collection-sections__article--image-size-large"> <a class="single-collection-sections__article-anchor" id="hiv-treatment-as-prevention-optimising-the-impact-of-expanded-hiv-treatment-programmes"></a> <div class="single-collection-sections__article-image-container"> <a class="single-collection-sections__article-image" href="http://dx.plos.org/10.1371/journal.pmed.1001258" data-src="/wp-content/uploads/sites/16/indirect/bbeb8081a447f592ba7f291260fdb6ed.jpg" title="10.1371/journal.pmed.1001258"></a> <div class="image-credit image-credit--tooltip"> <span class="image-credit__label">Image credit</span> <div class="image-credit__content">10.1371/journal.pmed.1001258</div> </div> </div> <div class="single-collection-sections__article-text"> <span class="single-collection-sections__article-label">PLOS Medicine</span> <span class="single-collection-sections__article-title"> <a href="http://dx.plos.org/10.1371/journal.pmed.1001258">HIV Treatment as Prevention: Optimising the Impact of Expanded HIV Treatment Programmes</a> </span> <div class="single-collection-sections__article-meta"> <span class="single-collection-sections__article-date">July 10, 2012</span> <span class="single-collection-sections__article-additional-meta-info">Wim Delva, Jeffrey Eaton, Fei Meng, Christophe Fraser, Richard White, Peter Vickerman, Marie-Claude Boily, Timothy Hallett</span> </div> </div> </li> <li class="single-collection-sections__article single-collection-sections__article--plos_article single-collection-sections__article--has-image-yes single-collection-sections__article--image-right single-collection-sections__article--image-size-large"> <a class="single-collection-sections__article-anchor" id="hiv-treatment-as-prevention-issues-in-economic-evaluation"></a> <div class="single-collection-sections__article-image-container"> <a class="single-collection-sections__article-image" href="http://dx.plos.org/10.1371/journal.pmed.1001263" data-src="/wp-content/uploads/sites/16/indirect/c106735c9717b9dc9fbd0ca62770473c.jpg" title="Psyberartist at flickr.com, Manta Ray Media/HIV Modelling Consortium"></a> <div class="image-credit image-credit--tooltip"> <span class="image-credit__label">Image credit</span> <div class="image-credit__content">Psyberartist at flickr.com, Manta Ray Media/HIV Modelling Consortium</div> </div> </div> <div class="single-collection-sections__article-text"> <span class="single-collection-sections__article-label">PLOS Medicine</span> <span class="single-collection-sections__article-title"> <a href="http://dx.plos.org/10.1371/journal.pmed.1001263">HIV Treatment as Prevention: Issues in Economic Evaluation</a> </span> <div class="single-collection-sections__article-meta"> <span class="single-collection-sections__article-date">July 10, 2012</span> <span class="single-collection-sections__article-additional-meta-info">Till B盲rnighausen, Joshua Salomon, Nalinee Sangrujee</span> </div> </div> </li> <li class="single-collection-sections__article single-collection-sections__article--plos_article single-collection-sections__article--has-image-yes single-collection-sections__article--image-right single-collection-sections__article--image-size-large"> <a class="single-collection-sections__article-anchor" id="hiv-treatment-as-prevention-modelling-the-cost-of-antiretroviral-treatment鈥攕tate-of-the-art-and-future-directions"></a> <div class="single-collection-sections__article-image-container"> <a class="single-collection-sections__article-image" href="http://dx.plos.org/10.1371/journal.pmed.1001247" data-src="/wp-content/uploads/sites/16/indirect/36ee02b4794f4e487dea8aec840017e9.jpg" title="10.1371/journal.pmed.1001247"></a> <div class="image-credit image-credit--tooltip"> <span class="image-credit__label">Image credit</span> <div class="image-credit__content">10.1371/journal.pmed.1001247</div> </div> </div> <div class="single-collection-sections__article-text"> <span class="single-collection-sections__article-label">PLOS Medicine</span> <span class="single-collection-sections__article-title"> <a href="http://dx.plos.org/10.1371/journal.pmed.1001247">HIV Treatment as Prevention: Modelling the Cost of Antiretroviral Treatment鈥擲tate of the Art and Future Directions</a> </span> <div class="single-collection-sections__article-meta"> <span class="single-collection-sections__article-date">July 10, 2012</span> <span class="single-collection-sections__article-additional-meta-info">Gesine Meyer-Rath, Mead Over</span> </div> </div> </li> <li class="single-collection-sections__article single-collection-sections__article--plos_article single-collection-sections__article--has-image-yes single-collection-sections__article--image-right single-collection-sections__article--image-size-large"> <a class="single-collection-sections__article-anchor" id="hiv-treatment-as-prevention-models-data-and-questions鈥攖owards-evidencebased-decisionmaking"></a> <div class="single-collection-sections__article-image-container"> <a class="single-collection-sections__article-image" href="http://dx.plos.org/10.1371/journal.pmed.1001259" data-src="/wp-content/uploads/sites/16/indirect/aab29dc13f32dcc6cec15d2a9d5ce753.jpg" title="10.1371/journal.pmed.1001259"></a> <div class="image-credit image-credit--tooltip"> <span class="image-credit__label">Image credit</span> <div class="image-credit__content">10.1371/journal.pmed.1001259</div> </div> </div> <div class="single-collection-sections__article-text"> <span class="single-collection-sections__article-label">PLOS Medicine</span> <span class="single-collection-sections__article-title"> <a href="http://dx.plos.org/10.1371/journal.pmed.1001259">HIV Treatment as Prevention: Models, Data, and Questions鈥擳owards Evidence-Based Decision-Making</a> </span> <div class="single-collection-sections__article-meta"> <span class="single-collection-sections__article-date">July 10, 2012</span> <span class="single-collection-sections__article-additional-meta-info">Timothy Hallett, Till B盲rnighausen, Stephen Becker, Eran Bendavid, Anna Bershteyn, John Blandford, Marie-Claude Boily, David Burns, Valentina Cambiano, Myron Cohen, 脥de Cremin, Wim Delva, Christopher Dye, Jeffrey Eaton, Matthias Egger, Christophe Fraser, Noya Galai, Geoff Garnett, Peter Ghys, Laura Heaton, Charles Holmes, Jan Hontelez, Britta Jewell, Olivia Keiser, Daniel Klein, Viviane Lima, Elisa Long, Rob Lyerla, Christiaan Marais, Fei Meng, Gesine Meyer-Rath, William Miller, Nicholas Muraguri, Brooke Nichols, Karima Nigmatulina, Mead Over, Nancy Padian, Andrew Phillips, Carel Pretorius, Christine Rousseau, Joshua Salomon, Nalinee Sangrujee, David Serwadda, Frank Tanser, Juan Vesga, Peter Vickerman, Damian Walker, Rui Wang, Alex Welte, Richard White, Brian Williams, David Wilson, David Wilson, Basia Zaba</span> </div> </div> </li> </ul> </div> <div class="single-collection-sections__section" id="research-article"> <span class="single-collection-sections__section-title">Research Article</span> <ul class="single-collection-sections__items"> <li class="single-collection-sections__article single-collection-sections__article--plos_article single-collection-sections__article--has-image-yes single-collection-sections__article--image-right single-collection-sections__article--image-size-large"> <a class="single-collection-sections__article-anchor" id="hiv-treatment-as-prevention-systematic-comparison-of-mathematical-models-of-the-potential-impact-of-antiretroviral-therapy-on-hiv-incidence-in-south-africa"></a> <div class="single-collection-sections__article-image-container"> <a class="single-collection-sections__article-image" href="http://dx.plos.org/10.1371/journal.pmed.1001245" data-src="/wp-content/uploads/sites/16/indirect/57430b003f1c4bdadba1023c829f9bc6.jpg" title="10.1371/journal.pmed.1001245"></a> <div class="image-credit image-credit--tooltip"> <span class="image-credit__label">Image credit</span> <div class="image-credit__content">10.1371/journal.pmed.1001245</div> </div> </div> <div class="single-collection-sections__article-text"> <span class="single-collection-sections__article-label">PLOS Medicine</span> <span class="single-collection-sections__article-title"> <a href="http://dx.plos.org/10.1371/journal.pmed.1001245">HIV Treatment as Prevention: Systematic Comparison of Mathematical Models of the Potential Impact of Antiretroviral Therapy on HIV Incidence in South Africa</a> </span> <div class="single-collection-sections__article-meta"> <span class="single-collection-sections__article-date">July 10, 2012</span> <span class="single-collection-sections__article-additional-meta-info">Jeffrey Eaton, Leigh Johnson, Joshua Salomon, Till B盲rnighausen, Eran Bendavid, Anna Bershteyn, David Bloom, Valentina Cambiano, Christophe Fraser, Jan Hontelez, Salal Humair, Daniel Klein, Elisa Long, Andrew Phillips, Carel Pretorius, John Stover, Edward Wenger, Brian Williams, Timothy Hallett</span> </div> </div> </li> </ul> </div> </div> <div class="single-collection-sidebar"> <div class="single-collection-sidebar__item single-collection-sidebar__item--rss-feeds"> <span class="single-collection-sidebar__item-title">PLOS Collections Blog - Medicine & Health Sciences</span> <div class="single-collection-sidebar__rss-feed" data-feed="http://blogs.plos.org/collections/topics/medicine-health-sciences/feed/"><div class="single-collection-sidebar__feed-loading"><p>Loading...</p></div></div> </div> <div class="single-collection-sidebar__item single-collection-sidebar__item--rich-text"> <span class="single-collection-sidebar__item-title">Collection Support</span> <p>The collection is produced with support from the HIV Modelling Consortium, which was funded by a grant from the Bill & Melinda Gates Foundation.</p> </div> </div> </div> </article> </main> </div> </div> <style 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